MCID: CRV040
MIFTS: 53

Cervix Carcinoma malady

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Cervix Carcinoma

Aliases & Descriptions for Cervix Carcinoma:

Name: Cervix Carcinoma 12 14 69
Carcinoma of the Cervix Uteri 12
Carcinoma Cervix Uteri 12
Carcinoma of Cervix 12
Cancer of Cervix 12
Cervical Cancer 69
Cervix Cancer 29

Classifications:



External Ids:

Disease Ontology 12 DOID:2893
NCIt 47 C9039
UMLS 69 C0302592

Summaries for Cervix Carcinoma

Disease Ontology : 12 A cervical cancer that is located in the cervix uteri or located in the cervical area and that has material basis in abnormally proliferating cells derives from epithelial cells.

MalaCards based summary : Cervix Carcinoma, also known as carcinoma of the cervix uteri, is related to poorly differentiated endocrine carcinoma of the cervix uteri and glassy cell carcinoma of the cervix uteri, and has symptoms including pelvic pain An important gene associated with Cervix Carcinoma is TP53 (Tumor Protein P53), and among its related pathways/superpathways are Cellular Senescence and DNA Damage. The drugs Cisplatin and Diazepam have been mentioned in the context of this disorder. Affiliated tissues include cervix, breast and heart, and related phenotypes are Decreased viability in esophageal squamous lineage and hematopoietic system

Related Diseases for Cervix Carcinoma

Diseases related to Cervix Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 40)
id Related Disease Score Top Affiliating Genes
1 poorly differentiated endocrine carcinoma of the cervix uteri 12.1
2 glassy cell carcinoma of the cervix uteri 12.1
3 adenoid basal carcinoma of the cervix uteri 12.1
4 papillary carcinoma of the cervix uteri 12.1
5 cervix uteri carcinoma in situ 10.9
6 cervical squamous cell carcinoma 10.9
7 cervical adenocarcinoma 10.9
8 malignant peripheral neuroectodermal tumor of cervix uteri 10.9
9 malignant germ cell tumor of cervix uteri 10.9
10 cervical cancer, somatic 10.8
11 papillary transitional carcinoma 10.2 FGFR3 FHIT TP53
12 clear cell adenofibroma 10.1 CDKN2A TP53
13 lacrimal gland adenoid cystic carcinoma 10.1 CDKN2A TP53
14 nodular basal cell carcinoma 10.1 ABCB1 ABCC1
15 pericardium leiomyoma 10.1 CDKN2A TP53
16 type 1 papillary adenoma of the kidney 10.1 FGFR3 TP53
17 uterine cervix leukoplakia 10.1 CDKN2A FHIT TP53
18 spondylarthropathy 10.1 CDKN2A TP53
19 breast leiomyoma 10.0 CDKN2A FGFR3 TP53
20 testicular fibroma 10.0 ABCB1 ABCC1 CDKN2A
21 spinal muscular atrophy with progressive myoclonic epilepsy 10.0 CDKN2A FHIT TP53
22 thanatophoric dysplasia, type ii 10.0 CDKN2A FGFR3 FHIT TP53
23 sternum lymphoma 9.9 CDKN2A MAPK8IP1 TP53
24 facial dermatosis 9.9 CDKN2A FHIT TP53
25 adult acute lymphocytic leukemia 9.9 ABCB1 CDKN2A TP53
26 phosphoserine phosphatase deficiency 9.9 ABCB1 ABCC1 CDKN2A NBN
27 trachea squamous cell carcinoma 9.9 CDKN2A MAPK8IP1 TP53
28 brain stem medulloblastoma 9.8 CDKN2A STAT3 TP53
29 hypogonadotropic hypogonadism 20 with or without anosmia 9.7 CDKN2A FHIT STAT3 TP53
30 cutis laxa, autosomal recessive, type ib 9.7 ABCB1 CDKN2A FGFR3 STAT3 TP53
31 urinary tract obstruction 9.6
32 glioma 9.6
33 brain glioma 9.6
34 vulva cancer 9.6
35 thyroiditis 9.5
36 hypoxia 9.5
37 burkitt lymphoma 9.5
38 lymphoma 9.5
39 cervicitis 9.5
40 cryoglobulinemia 7.9 ABCB1 ABCC1 ARHGAP8 BECN1 CDC27 CDKN2A

Graphical network of the top 20 diseases related to Cervix Carcinoma:



Diseases related to Cervix Carcinoma

Symptoms & Phenotypes for Cervix Carcinoma

UMLS symptoms related to Cervix Carcinoma:


pelvic pain

GenomeRNAi Phenotypes related to Cervix Carcinoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in esophageal squamous lineage GR00235-A 9.32 BECN1 CDKN2A CDKN3 DUSP3 FGFR3 MAPK8IP1

MGI Mouse Phenotypes related to Cervix Carcinoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.11 ABCB1 ABCC1 BECN1 CDKN2A DUSP3 FGFR3
2 homeostasis/metabolism MP:0005376 10.1 ABCB1 ABCC1 BECN1 CDKN2A DUSP3 FGFR3
3 mortality/aging MP:0010768 10.03 ABCB1 ABCC1 BECN1 CDKN2A FGFR3 FHIT
4 digestive/alimentary MP:0005381 9.95 SLC16A1 STAT3 TP53 ABCB1 CDKN2A FGFR3
5 neoplasm MP:0002006 9.7 BECN1 CDKN2A FGFR3 FHIT NBN STAT3
6 nervous system MP:0003631 9.65 RHOA STAT3 TP53 ABCB1 ABCC1 BECN1
7 reproductive system MP:0005389 9.23 ABCB1 BECN1 CDKN2A FGFR3 MAPK8IP1 NBN

Drugs & Therapeutics for Cervix Carcinoma

Drugs for Cervix Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 447)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
2
Diazepam Approved, Illicit, Vet_approved Phase 4 439-14-5 3016
3
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3 437-38-7 3345
4
Meperidine Approved Phase 4 57-42-1 4058
5
Nicotine Approved Phase 4,Phase 1,Phase 2 54-11-5 942 89594
6
Aluminum hydroxide Approved Phase 4,Phase 3,Phase 2 21645-51-2
7
Iron Approved Phase 4 7439-89-6 23925
8
Bethanechol Approved Phase 4 674-38-4 2370
9
Vitamin C Approved, Nutraceutical Phase 4,Phase 2 50-81-7 5785 54670067
10 Vaccines Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
11 Liver Extracts Phase 4,Phase 3,Phase 2,Phase 1
12 Epoetin alfa Phase 4,Phase 3 113427-24-0
13 Hematinics Phase 4,Phase 3,Phase 2,Phase 1
14 Anesthetics Phase 4,Phase 3,Phase 2,Early Phase 1
15 Anesthetics, General Phase 4,Phase 3
16 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Early Phase 1
17 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
18 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
19 Antibodies Phase 4,Phase 3,Phase 2,Phase 1
20 Immunoglobulins Phase 4,Phase 3,Phase 2,Phase 1
21 Adjuvants, Anesthesia Phase 4,Phase 3
22 Analgesics Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1
23 Analgesics, Opioid Phase 4,Phase 3
24 Anesthetics, Intravenous Phase 4,Phase 3
25 Narcotics Phase 4,Phase 3,Early Phase 1
26 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1
27 Disinfectants Phase 4
28 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1
29 Polyhexamethylene biguanide Phase 4
30 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
31 Central Nervous System Stimulants Phase 4,Phase 1,Phase 2
32 Cholinergic Agents Phase 4,Phase 1,Phase 2
33 Nicotinic Agonists Phase 4,Phase 1,Phase 2
34 Micronutrients Phase 4,Phase 3,Phase 1,Phase 2
35 Trace Elements Phase 4,Phase 3,Phase 1,Phase 2
36 Vitamins Phase 4,Phase 3,Phase 1,Phase 2
37 Ferrous fumarate Phase 4
38 Monophosphoryl lipid A Phase 4
39 Peppermint Nutraceutical Phase 4
40 Calamus Nutraceutical Phase 4
41
Gemcitabine Approved Phase 3,Phase 2,Phase 1 95058-81-4 60750
42
Hydralazine Approved Phase 3,Phase 2 86-54-4 3637
43
Topotecan Approved, Investigational Phase 3,Phase 2,Phase 1 119413-54-6, 123948-87-8 60700
44
Valproic Acid Approved, Investigational Phase 3,Phase 2 99-66-1 3121
45
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1 33069-62-4 36314
46
Menthol Approved Phase 2, Phase 3, Phase 1 2216-51-5 16666
47
Fluorouracil Approved Phase 3,Phase 2,Phase 1 51-21-8 3385
48
Vinblastine Approved Phase 3,Phase 1 865-21-4 13342 241903
49
Vinorelbine Approved, Investigational Phase 3,Phase 2,Phase 1 71486-22-1 60780 44424639
50
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904

Interventional clinical trials:

(show top 50) (show all 1158)
id Name Status NCT ID Phase
1 Primary and Secondary Prevention of Human Papillomavirus (HPV) Disease in China Unknown status NCT01021904 Phase 4
2 Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls? Unknown status NCT01101750 Phase 4
3 The Self-Collection Study: a Study of Self-collected HPV Testing and Results Counseling Unknown status NCT01843478 Phase 4
4 Can Alternative Treatment Have an Impact on Cervical Dysplasia? Unknown status NCT00842738 Phase 4
5 Immune Response After Human Papillomavirus Vaccination in Patients With Autoimmune Disease Unknown status NCT00815282 Phase 4
6 Influence of Gum Chewing on Postoperative Bowel Activity After Complete Staging Surgery for Gynecological Malignancies Unknown status NCT01835119 Phase 4
7 Comparing the Rate of Insufficient Cells for Diagnosis Between Surepath® and Conventional Smear in Women After Radiation Therapy for Cervical Cancer Completed NCT01988376 Phase 4
8 Epoetin Beta in Treating Anemia in Patients With Cervical Cancer Completed NCT00046969 Phase 4
9 Effect of HPV Vaccination on Women Aged 25 Years Completed NCT02296255 Phase 4
10 Patient Navigation in the Safety Net:CONNECTeDD Completed NCT00613275 Phase 4
11 Delivery, Uptake and Acceptability of HPV Vaccination in Tanzanian Girls Completed NCT01173900 Phase 4
12 V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110) Completed NCT01544478 Phase 4
13 Evaluation of Long-term Immunogenicity and Safety of a Human Papillomavirus (HPV) Vaccine in Healthy Female Subjects Completed NCT00947115 Phase 4
14 Alternate Dosing Schedules Study for HPV Vaccine (ADS) Completed NCT02280642 Phase 4
15 Alternate Dosing Schedules Study for HPV Vaccine Completed NCT00862810 Phase 4
16 Reactogenicity Study of Cervarix and Gardasil in UK Adolescent Girls Completed NCT00956553 Phase 4
17 Comparison of Meperidine and Fentanyl on Pain Scale and QOL in Brachytherapy Completed NCT02684942 Phase 4
18 Effectiveness, Safety and Immunogenicity of GSK Biologicals' HPV Vaccine GSK580299 (Cervarix TM) Administered in Healthy Adolescents Completed NCT00534638 Phase 4
19 Polyhexamethylene Biguanide Increases the Regression Rate of Human Papillomavirus (HPV) Infection Completed NCT01571141 Phase 4
20 Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking Completed NCT00365508 Phase 4
21 Comparing Health Services Interventions for the Prevention of HPV-related Cancer Recruiting NCT02837926 Phase 4
22 Transmission Reduction and Prevention With HPV Vaccination (TRAP-HPV) Study Recruiting NCT01824537 Phase 4
23 Oral Iron vs. Placebo in Newly Diagnosed Gynecologic Oncology Patients Who Are Surgical Candidates. Recruiting NCT01953107 Phase 4
24 CervIcal Cancer Screening Trial by Randomization of HPV Testing Intervention for Upcoming Screening (CITRUS Study) Active, not recruiting NCT01895517 Phase 4
25 FASTER-Tlalpan Study Active, not recruiting NCT03105856 Phase 4
26 The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP) Active, not recruiting NCT02629510 Phase 4
27 Trial of Two Versus Three Doses of Human Papillomavirus (HPV) Vaccine in India Active, not recruiting NCT00923702 Phase 4
28 Evaluation of Safety and Immunogenicity of a Human Papillomavirus (HPV) Vaccine in Human Immunodeficiency Virus (HIV) Infected Females Active, not recruiting NCT01031069 Phase 4
29 Immunogenicity and Safety of Human Papilloma Virus Vaccine in Solid Organ Transplant Recipients Active, not recruiting NCT02624349 Phase 4
30 Ohio Patient Navigator Research Program Active, not recruiting NCT01569672 Phase 4
31 Scientific Evaluation of One or Two Doses of the Bivalent or Nonavalent Prophylactic HPV Vaccines Not yet recruiting NCT03180034 Phase 4
32 Effectiveness of Bethanechol Chloride and Early Bladder Training for Prevention of Bladder Dysfunction After Radical Hysterectomy in Cervical Cancer Stage IB - IIA Not yet recruiting NCT02910596 Phase 4
33 HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions Not yet recruiting NCT03051516 Phase 4
34 Dissemination of Cervical Cancer Screening to Primary Care Physicians in Underserved Communities Terminated NCT00629993 Phase 4
35 Evaluate Safety of a Vaccine Against Cervical Cancer (HPV-16/18 L1/AS04) in Healthy Filipino Females Aged 10 Yrs & Above Terminated NCT00730847 Phase 4
36 Cisplatin Based Chemoradiation v.s Radiotherapy for Cervical Cancer and With Clinically Defined Good Prognosis Unknown status NCT00846508 Phase 3
37 Randomized Trial Between Weekly and 5 Day 3 Weekly Cisplatin for Cervical Cancer Unknown status NCT00548821 Phase 3
38 Radiotherapy With Single-Agent Cisplatin or Combination Chemotherapy in Defined Poor-Prognostic Cervical Cancer Unknown status NCT00842660 Phase 3
39 Usefulness of FDG-PET for Advanced Cervical Cancer Unknown status NCT00146458 Phase 3
40 Impact of Erythropoietin Administration During Definitive Cervix Cancer Radiotherapy on Treatment Outcome Unknown status NCT00348738 Phase 3
41 Hydralazine Valproate for Cervical Cancer Unknown status NCT00532818 Phase 3
42 Study on Paclitaxel Plus Topotecan in Comparison With Topotecan Plus Cisplatin in Recurrent or Persistent Cervical Carcinoma Unknown status NCT01405235 Phase 3
43 Randomized Trial of Vaginal Self Sampling for Human Papillomavirus (HPV) Unknown status NCT01095198 Phase 2, Phase 3
44 Clinical and Experimental Studies to Improve Radiotherapy Outcome in AIDS Cancer Patients Unknown status NCT00122746 Phase 3
45 Study to Prevent Radiation Induced Damage to Bowel Using a Prebiotic Enhanced Diet. Unknown status NCT01414517 Phase 3
46 The Assessment of Preoperative Psychological Intervention on Stress in Women With Gynecological Malignancies Unknown status NCT00726635 Phase 3
47 Two-dose Schedule of Quadrivalent HPV Recombinant Vaccine in 11-year-old Boys in Mexico City Unknown status NCT02382900 Phase 3
48 Single-port Access Laparoscopic-assisted Vaginal Hysterectomy Unknown status NCT01048931 Phase 3
49 Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer Unknown status NCT01087268 Phase 3
50 Partnership for Healthy Seniors Unknown status NCT00379743 Phase 3

Search NIH Clinical Center for Cervix Carcinoma

Genetic Tests for Cervix Carcinoma

Genetic tests related to Cervix Carcinoma:

id Genetic test Affiliating Genes
1 Carcinoma of Cervix 29

Anatomical Context for Cervix Carcinoma

MalaCards organs/tissues related to Cervix Carcinoma:

39
Cervix, Breast, Heart, Thyroid

The Foundational Model of Anatomy Ontology organs/tissues related to Cervix Carcinoma:

18
The Cervix Uteri Or

Publications for Cervix Carcinoma

Articles related to Cervix Carcinoma:

(show all 45)
id Title Authors Year
1
Dosimetric influence of filtered and flattening filter free photon beam on rapid arc (RA) radiotherapy planning in case of cervix carcinoma. ( 27790073 )
2017
2
STAT3:FOXM1 and MCT1 drive uterine cervix carcinoma fitness to a lactate-rich microenvironment. ( 26563366 )
2016
3
Comparison of dosimetric parameters and acute toxicity of intensity-modulated and three-dimensional radiotherapy in patients with cervix carcinoma: A randomized prospective study. ( 27368915 )
2016
4
Image-Guided High-Dose Rate Brachytherapy in Cervix Carcinoma Using Balloon Catheter and Belt Immobilization System. ( 26868850 )
2016
5
Modulation of RhoA GTPase Activity Sensitizes Human Cervix Carcinoma Cells to I^-Radiation by Attenuating DNA Repair Pathways. ( 26649141 )
2016
6
Dosimetric study for cervix carcinoma treatment using intensity modulated radiation therapy (IMRT) compensation based on 3D intracavitary brachytherapy technique. ( 27504132 )
2016
7
RGDS- and TAT-Conjugated Upconversion of NaYF4:Yb(3+)/Er(3+)&SiO2 Nanoparticles: In Vitro Human Epithelioid Cervix Carcinoma Cellular Uptake, Imaging, and Targeting. ( 27428386 )
2016
8
SU-F-T-62: Three-Dimensional Dosimetric Gamma Analysis for Impacts of Tissue Inhomogeneity Using Monte Carlo Simulation in Intracavitary Brachytheray for Cervix Carcinoma. ( 28048200 )
2016
9
Evaluation of outcome and prognostic factors in 739 patients with uterine cervix carcinoma: a single institution experience. ( 26034391 )
2015
10
Metastatic lobular carcinoma of breast mimics primary cervix carcinoma: two case reports and a review of the literature. ( 26435744 )
2015
11
Systematic gene microarray analysis of the lncRNA expression profiles in human uterine cervix carcinoma. ( 26054679 )
2015
12
The dosimetric impact of different photon beam energy on RapidArc radiotherapy planning for cervix carcinoma. ( 26865756 )
2015
13
Synthetic racemates of abyssinone I and II induces apoptosis through mitochondrial pathway in human cervix carcinoma cells. ( 25019692 )
2014
14
Cervix carcinoma and incidental finding of medullary thyroid carcinoma by 18F-FDG PET/CT--clinical case. ( 25088110 )
2014
15
Pulsed-dose-rate brachytherapy for uterine cervix carcinoma: 10 years of experience with 226 patients at a single institution. ( 23880416 )
2013
16
Bladder-rectum spacer balloon in high-dose-rate brachytherapy in cervix carcinoma. ( 23517809 )
2013
17
Ultrasound-assisted endocavitary HDR-Ir(192) brachytherapy for unresectable locally advanced uterine cervix carcinoma: retrospective analysis focusing the efficacy and tolerability. ( 22855184 )
2013
18
Cervix carcinoma or Burkitt lymphoma metastases in meningiomas, two case reports. ( 23318021 )
2013
19
A ROS-mediated lysosomal-mitochondrial pathway is induced by a novel Amonafide analogue, 7c, in human Hela cervix carcinoma cells. ( 23376642 )
2013
20
Early clinical outcomes and toxicity of intensity modulated versus conventional pelvic radiation therapy for locally advanced cervix carcinoma: a prospective randomized study. ( 24074927 )
2013
21
Proteomic analysis reveals tanshinone IIA enhances apoptosis of advanced cervix carcinoma CaSki cells through mitochondria intrinsic and endoplasmic reticulum stress pathways. ( 24167031 )
2013
22
Impact of 3D image-based PDR brachytherapy on outcome of patients treated for cervix carcinoma in France: results of the French STIC prospective study. ( 22633469 )
2012
23
Concomitant boost plus large-field preoperative chemoradiation in locally advanced uterine cervix carcinoma: Phase II clinical trial final results (LARA-CC-1). ( 22425663 )
2012
24
Hypoxia imaging of uterine cervix carcinoma with (18)F-FETNIM PET/CT. ( 22996235 )
2012
25
Uterine cervix carcinoma: recent biological data and update for improving follow-up and treatment. ( 23240379 )
2012
26
Co-overexpression of bcl-2 and c-myc in uterine cervix carcinomas and premalignant lesions. ( 21556123 )
2011
27
Synergistic action of doxorubicin and sulindac in human cervix carcinoma cells - studies on possible mechanisms. ( 20037485 )
2010
28
Roscovitine up-regulates p53 protein and induces apoptosis in human HeLaS(3) cervix carcinoma cells. ( 18846503 )
2008
29
Reactive oxygen species and nitric oxide regulate mitochondria-dependent apoptosis and autophagy in evodiamine-treated human cervix carcinoma HeLa cells. ( 18484413 )
2008
30
Effect of NBS1 gene polymorphism on the risk of cervix carcinoma in a northern Indian population. ( 18949738 )
2008
31
Microarray analysis of normal cervix, carcinoma in situ, and invasive cervical cancer: identification of candidate genes in pathogenesis of invasion in cervical cancer. ( 18217980 )
2008
32
Cervix carcinoma is associated with an up-regulation and nuclear localization of the dual-specificity protein phosphatase VHR. ( 18505570 )
2008
33
CDC27 protein is involved in radiation response in squamous cell cervix carcinoma. ( 23923534 )
2005
34
Microarray comparative genomic hybridization detection of chromosomal imbalances in uterine cervix carcinoma. ( 16004614 )
2005
35
Keratins 8, 10, 13, and 17 are useful markers in the diagnosis of human cervix carcinomas. ( 15138927 )
2004
36
Overexpression of the c-Met/HGF receptor and its prognostic significance in uterine cervix carcinomas. ( 12586590 )
2003
37
Growth inhibition of cervix carcinoma cells in vivo by endothelin A receptor blockade. ( 12438219 )
2002
38
Stage IIa cervix carcinoma with metastasis to the heart: report of a case with immunohistochemistry, flow cytometry, and virology findings. ( 10620458 )
2000
39
Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. ( 10471491 )
1999
40
Expression of transglutaminase K in normal cervix tissue and cervix carcinomas. ( 10405818 )
1999
41
Response to radiotherapy of human uterine cervix carcinoma is not correlated with rearrangements of the Ha-ras-1 and/or c-myc genes. ( 9291819 )
1997
42
Cathepsin B in predicting the extent of the cervix carcinoma. ( 7617069 )
1995
43
[CD44 splice variants as prognostic factors in invasive cervix carcinoma]. ( 7537136 )
1995
44
c-erbB-2 oncoprotein overexpression in uterine cervix carcinoma with glandular differentiation. A frequent event but not an independent prognostic marker because it occurs late in the disease. ( 8526205 )
1995
45
Genomic alterations of the c-myc protooncogene in relation to the overexpression of c-erbB2 and Ki-67 in human breast and cervix carcinomas. ( 1683873 )
1991

Variations for Cervix Carcinoma

ClinVar genetic disease variations for Cervix Carcinoma:

6
id Gene Variation Type Significance SNP ID Assembly Location
1 FGFR3 NM_000142.4(FGFR3): c.746C> G (p.Ser249Cys) single nucleotide variant Pathogenic/Likely pathogenic rs121913483 GRCh37 Chromosome 4, 1803568: 1803568

Expression for Cervix Carcinoma

Search GEO for disease gene expression data for Cervix Carcinoma.

Pathways for Cervix Carcinoma

GO Terms for Cervix Carcinoma

Cellular components related to Cervix Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.73 ARHGAP8 BECN1 CDC27 CDKN2A CDKN3 DUSP3
2 mitochondrion GO:0005739 9.23 BECN1 CDKN2A FHIT MAPK8IP1 RHOA SLC16A1

Biological processes related to Cervix Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 phosphatidylinositol-mediated signaling GO:0048015 9.65 FGFR3 RHOA TP53
2 negative regulation of cell proliferation GO:0008285 9.65 BECN1 CDKN2A CDKN3 STAT3 TP53
3 peptidyl-tyrosine dephosphorylation GO:0035335 9.63 CDKN3 DUPD1 DUSP3
4 cell cycle GO:0007049 9.63 BECN1 CDKN2A CDKN3 NBN RHOA TP53
5 DNA damage response, signal transduction by p53 class mediator GO:0030330 9.43 NBN TP53
6 replicative senescence GO:0090399 9.4 CDKN2A TP53
7 regulation of mitochondrial membrane permeability GO:0046902 9.37 STAT3 TP53
8 xenobiotic transport GO:0042908 9.32 ABCB1 ABCC1
9 cell cycle arrest GO:0007050 9.26 CDKN2A CDKN3 NBN TP53
10 response to drug GO:0042493 9.02 ABCB1 ABCC1 BECN1 RHOA STAT3

Molecular functions related to Cervix Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transcription factor binding GO:0008134 9.67 CDKN2A NBN STAT3 TP53
2 protein tyrosine phosphatase activity GO:0004725 9.5 CDKN3 DUPD1 DUSP3
3 protein phosphatase binding GO:0019903 9.43 CDC27 STAT3 TP53
4 protein kinase binding GO:0019901 9.35 CDKN2A DUSP3 MAPK8IP1 STAT3 TP53
5 xenobiotic-transporting ATPase activity GO:0008559 9.16 ABCB1 ABCC1
6 protein tyrosine/serine/threonine phosphatase activity GO:0008138 8.8 CDKN3 DUPD1 DUSP3

Sources for Cervix Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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