MCID: CRV069
MIFTS: 33

Cervix Disease

Categories: Reproductive diseases

Aliases & Classifications for Cervix Disease

MalaCards integrated aliases for Cervix Disease:

Name: Cervix Disease 12 14
Uterine Cervical Diseases 42
Cervix Disorders 41
Cervix Diseases 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2253
MeSH 42 D002577
NCIt 47 C40241
UMLS 69 C0007867

Summaries for Cervix Disease

MedlinePlus : 41 the cervix is the lower part of the uterus, the place where a baby grows during pregnancy. the cervix has a small opening that expands during childbirth. it also allows menstrual blood to leave a woman's body. your health care provider may perform a pap test during your health checkup to look for changes to the cells of the cervix, including cervical cancer. other problems with the cervix include: cervicitis - inflammation of the cervix. this is usually from an infection. cervical incompetence - this can happen during pregnancy. the opening of the cervix widens long before the baby is due. cervical polyps and cysts - abnormal growths on the cervix

MalaCards based summary : Cervix Disease, also known as uterine cervical diseases, is related to larynx carcinoma in situ and cervical polyp, and has symptoms including pelvic pain An important gene associated with Cervix Disease is MT-TG (Mitochondrially Encoded TRNA Glycine). The drugs Azithromycin and Doxycycline have been mentioned in the context of this disorder. Affiliated tissues include cervix, testes and lymph node, and related phenotype is cardiovascular system.

Wikipedia : 72 The cervix or cervix uteri (Latin: neck of the uterus) is the lower part of the uterus in the human... more...

Related Diseases for Cervix Disease

Diseases related to Cervix Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 150)
id Related Disease Score Top Affiliating Genes
1 larynx carcinoma in situ 10.7 CDKN2A SERPIND1
2 cervical polyp 10.7
3 cervical incompetence 10.7
4 intracranial chondrosarcoma 10.7 CD79A FLNA
5 orofaciodigital syndrome vii 10.6 FLNA MRAP
6 primary lacrimal atrophy 10.6 CD79A MRAP
7 infancy electroclinical syndrome 10.5 CXCL8 SERPINH1
8 nephrosclerosis 10.5 CD79A SERPINH1
9 fallopian tube carcinoma 10.5 CD79A CXCL8
10 inclusion conjunctivitis 10.5 CD79A MRAP
11 osteogenesis imperfecta, type x 10.5 CXCL8 SERPINH1
12 plantar wart 10.5 CD79A CXCL8
13 subglottis neoplasm 10.5 CXCL8 SERPINH1
14 carbuncle 10.4 CXCL8 SERPINH1
15 tricuspid valve prolapse 10.4 MRAP SERPINH1
16 alcoholic neuropathy 10.4 CD40LG CD79A
17 calloso-genital dysplasia 10.4 CD40LG CD79A
18 variola major 10.4 CD40LG CD79A
19 mu chain disease 10.4 CD40LG CD79A
20 rabies 10.4 CD40LG CD79A
21 familial retinoblastoma 10.4 CD40LG CD79A
22 capillary leak syndrome 10.4 CXCL8 MRAP
23 microinvasive cervical squamous cell carcinoma 10.4 CD40LG CD79A
24 fetal erythroblastosis 10.4 CD40LG CD79A
25 spinal canal and spinal cord meningioma 10.4 CD40LG CD79A
26 trichostrongyloidiasis 10.4 CD40LG CD79A
27 leukodystrophy 10.4 CD40LG CD79A
28 retinal microaneurysm 10.4 CD40LG CD79A
29 heart septal defect 10.4 CD40LG CD79A
30 cryptorchidism arachnodactyly mental retardation 10.4 CD40LG CD79A
31 acute kidney tubular necrosis 10.4 CD40LG CD79A
32 secretory meningioma 10.4 CD40LG CD79A
33 hodgkin's lymphoma, nodular sclerosis 10.4 CD40LG CD79A
34 fetal akinesia deformation sequence 10.4 CD40LG MT-TG
35 imperforate oropharynx-costo vetebral anomalies 10.4 CD40LG CD79A
36 malignant otitis externa 10.4 CD40LG CD79A
37 transient hypogammaglobulinemia 10.4 CD40LG CD79A
38 benign epilepsy with centrotemporal spikes 10.4 CD40LG CD79A
39 tongue cancer 10.4 CD40LG CD79A
40 hydrops of gallbladder 10.4 CD40LG CD79A
41 gamma heavy chain disease 10.4 CD40LG CD79A
42 diabetic angiopathy 10.4 CD40LG CD79A
43 rosacea conjunctivitis 10.4 CD40LG CD79A
44 viral meningitis 10.4 CD40LG CD79A
45 heart fibrosarcoma 10.4 CD40LG CD79A
46 alopecia areata 10.4 CD40LG CD79A
47 kidney carcinoma in situ 10.4 CD40LG CD79A
48 dumping syndrome 10.4 CD40LG CD79A
49 leiomyosarcoma 10.4 CD40LG CD79A
50 periarthritis 10.4 CD40LG CD79A

Graphical network of the top 20 diseases related to Cervix Disease:



Diseases related to Cervix Disease

Symptoms & Phenotypes for Cervix Disease

UMLS symptoms related to Cervix Disease:


pelvic pain

MGI Mouse Phenotypes related to Cervix Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.1 CD40LG CDKN2A FLNA SERPIND1 SERPINH1 YME1L1

Drugs & Therapeutics for Cervix Disease

Drugs for Cervix Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 424)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 53477736 447043
2
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2 564-25-0 54671203
3
Lymecycline Approved Phase 4 992-21-2 5280963
4
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
5
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
6
Bupropion Approved Phase 4,Phase 2 34841-39-9, 34911-55-2 444
7
Dopamine Approved Phase 4,Phase 2 51-61-6, 62-31-7 681
8
Nicotine Approved Phase 4 54-11-5 942 89594
9
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
10
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
11
Iron Approved Phase 4,Phase 1,Phase 2 7439-89-6 23925
12
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
13
Chloroprocaine Approved Phase 4 133-16-4 8612
14
Procaine Approved, Investigational, Vet_approved Phase 4 59-46-1 4914
15
Vitamin C Approved, Nutraceutical Phase 4,Phase 2 50-81-7 5785 54670067
16 Vaccines Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
17 Liver Extracts Phase 4,Phase 2,Phase 1
18 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
19 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1
20 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
21 Antimalarials Phase 4,Phase 2,Phase 1
22 Antiparasitic Agents Phase 4,Phase 2,Phase 3,Phase 1
23 Antiprotozoal Agents Phase 4,Phase 2,Phase 3,Phase 1
24 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
25 Psychotropic Drugs Phase 4,Phase 3,Phase 2
26 Epoetin alfa Phase 4,Phase 3 113427-24-0
27 Hematinics Phase 4,Phase 3,Phase 2,Phase 1
28 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Early Phase 1
29 Antidepressive Agents Phase 4,Phase 2
30 Antidepressive Agents, Second-Generation Phase 4,Phase 2
31 Cytochrome P-450 CYP2D6 Inhibitors Phase 4,Phase 2
32 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 2
33 Dopamine Agents Phase 4,Phase 2
34 Dopamine Uptake Inhibitors Phase 4,Phase 2
35 Neurotransmitter Uptake Inhibitors Phase 4,Phase 2
36 Autonomic Agents Phase 4,Phase 3,Phase 2
37 Central Nervous System Stimulants Phase 4,Phase 2
38 Cholinergic Agents Phase 4
39 Nicotinic Agonists Phase 4
40 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
41 Anesthetics Phase 4,Phase 3,Phase 2,Early Phase 1
42 Anesthetics, Local Phase 4,Phase 3,Phase 2
43 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1,Phase 2
44 Micronutrients Phase 4,Phase 1,Phase 2
45 Trace Elements Phase 4,Phase 1,Phase 2
46 Vitamins Phase 4,Phase 1,Phase 2
47 Adjuvants, Anesthesia Phase 4
48 Analgesics Phase 4,Phase 1,Phase 2,Early Phase 1
49 Analgesics, Opioid Phase 4
50 Anesthetics, General Phase 4

Interventional clinical trials:

(show top 50) (show all 1013)

id Name Status NCT ID Phase Drugs
1 Primary and Secondary Prevention of Human Papillomavirus (HPV) Disease in China Unknown status NCT01021904 Phase 4
2 Can Alternative Treatment Have an Impact on Cervical Dysplasia? Unknown status NCT00842738 Phase 4
3 Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls? Unknown status NCT01101750 Phase 4
4 Time to Eradication of Mycoplasma Genitalium and Chlamydia Trachomatis After Treatment Commenced Unknown status NCT01661985 Phase 4 Azithromycin;Doxycycline;lymecycline
5 Management of Cervical Intraepithelial Neoplasia Grade 2 Completed NCT00733109 Phase 4
6 Effect of HPV Vaccination on Women Aged 25 Years Completed NCT02296255 Phase 4
7 Alternate Dosing Schedules Study for HPV Vaccine (ADS) Completed NCT02280642 Phase 4
8 Comparing the Rate of Insufficient Cells for Diagnosis Between Surepath® and Conventional Smear in Women After Radiation Therapy for Cervical Cancer Completed NCT01988376 Phase 4
9 Delivery, Uptake and Acceptability of HPV Vaccination in Tanzanian Girls Completed NCT01173900 Phase 4
10 Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease Completed NCT01034358 Phase 4
11 Alternate Dosing Schedules Study for HPV Vaccine Completed NCT00862810 Phase 4
12 Patient Navigation in the Safety Net:CONNECTeDD Completed NCT00613275 Phase 4
13 V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110) Completed NCT01544478 Phase 4
14 Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking Completed NCT00666978 Phase 4 bupropion hydrochloride
15 Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking Completed NCT00365508 Phase 4 nicotine lozenge;nicotine patch
16 Epoetin Beta in Treating Anemia in Patients With Cervical Cancer Completed NCT00046969 Phase 4 cisplatin
17 Role of Intrauterine Cornual Block in Combination With Direct Cervical Block in Outpatient Endometrial Ablation Completed NCT01808898 Phase 4
18 A Study of Korean Society of Spine Surgery on the Outcomes of Anterior Cervical Discectomy and Fusion Recruiting NCT01911013 Phase 4
19 HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions Recruiting NCT03051516 Phase 4
20 Comparing Health Services Interventions for the Prevention of HPV-related Cancer Recruiting NCT02837926 Phase 4
21 Oral Iron vs. Placebo in Newly Diagnosed Gynecologic Oncology Patients Who Are Surgical Candidates. Recruiting NCT01953107 Phase 4
22 The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP) Active, not recruiting NCT02629510 Phase 4 Tachosil
23 Ohio Patient Navigator Research Program Active, not recruiting NCT01569672 Phase 4
24 CervIcal Cancer Screening Trial by Randomization of HPV Testing Intervention for Upcoming Screening (CITRUS Study) Active, not recruiting NCT01895517 Phase 4
25 Trial of Two Versus Three Doses of Human Papillomavirus (HPV) Vaccine in India Active, not recruiting NCT00923702 Phase 4
26 Effectiveness of Cervical Screening in HPV Vaccinated Women Enrolling by invitation NCT02149030 Phase 4
27 Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage Not yet recruiting NCT03305575 Phase 4 Chloroprocaine;Bupivacaine
28 Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal) Not yet recruiting NCT02862912 Phase 4 Chloroprocaine;Bupivacaine;Fentanyl;Saline
29 To Evaluate the Efficacy and Safety of PEG-rhG-CSF(Jinyouli®) in Reducing Neutropenia in Patients With Cervical Cancer Not yet recruiting NCT03206684 Phase 4 PEG-rhG-CSF;rhG-CSF
30 Scientific Evaluation of One or Two Doses of the Bivalent or Nonavalent Prophylactic HPV Vaccines Not yet recruiting NCT03180034 Phase 4
31 Dissemination of Cervical Cancer Screening to Primary Care Physicians in Underserved Communities Terminated NCT00629993 Phase 4
32 Impact of Erythropoietin Administration During Definitive Cervix Cancer Radiotherapy on Treatment Outcome Unknown status NCT00348738 Phase 3 Erythropoietin
33 The IMAP Study Improving Management of Mildly Abnormal Pap Smears Unknown status NCT00119509 Phase 3
34 Clinical and Experimental Studies to Improve Radiotherapy Outcome in AIDS Cancer Patients Unknown status NCT00122746 Phase 3
35 Partnership for Healthy Seniors Unknown status NCT00379743 Phase 3
36 The Assessment of Preoperative Psychological Intervention on Stress in Women With Gynecological Malignancies Unknown status NCT00726635 Phase 3
37 Randomized Trial Between Weekly and 5 Day 3 Weekly Cisplatin for Cervical Cancer Unknown status NCT00548821 Phase 3 Cisplatin
38 A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls Unknown status NCT02562508 Phase 3
39 Study on Paclitaxel Plus Topotecan in Comparison With Topotecan Plus Cisplatin in Recurrent or Persistent Cervical Carcinoma Unknown status NCT01405235 Phase 3 Paclitaxel;Cisplatin/Paclitaxel
40 Cisplatin Based Chemoradiation v.s Radiotherapy for Cervical Cancer and With Clinically Defined Good Prognosis Unknown status NCT00846508 Phase 3 Cisplatin
41 Radiotherapy With Single-Agent Cisplatin or Combination Chemotherapy in Defined Poor-Prognostic Cervical Cancer Unknown status NCT00842660 Phase 3 Gemzar (gemcitabine)
42 Hydralazine Valproate for Cervical Cancer Unknown status NCT00532818 Phase 3 Hydralazine and magnesium valproate;Placebo
43 Usefulness of FDG-PET for Advanced Cervical Cancer Unknown status NCT00146458 Phase 3
44 Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer Unknown status NCT01087268 Phase 3
45 Concurrent Chemoradiotherapy With Weekly Cisplatin Versus Concurrent Chemoradiotherapy With Weekly Cisplatin and Paclitaxel in Locally Advanced Carcinoma Cervix Unknown status NCT01593306 Phase 3 Paclitaxel, Cisplatin;Cisplatin
46 Immunogenicity Bridge Between an Investigational Monovalent Vaccine and the Equivalent Component of Gardasil (V501) a Quadrivalent Vaccine (V501-012)(COMPLETED) Completed NCT00092482 Phase 3
47 Clinical Evaluation of the APTIMA® HPV Assay Using the TIGRIS® System Completed NCT00973362 Phase 3
48 A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected Women Completed NCT00000758 Phase 3 Fluorouracil
49 Noncarious Cervical Lesion Treatment Outcomes Completed NCT00867997 Phase 3
50 Safety and Effectiveness of Giving Isotretinoin to HIV-Infected Women to Treat Cervical Tumors Completed NCT00001073 Phase 3 Isotretinoin

Search NIH Clinical Center for Cervix Disease

Cochrane evidence based reviews: uterine cervical diseases

Genetic Tests for Cervix Disease

Anatomical Context for Cervix Disease

MalaCards organs/tissues related to Cervix Disease:

39
Cervix, Testes, Lymph Node, Uterus, Breast, T Cells, Prostate

Publications for Cervix Disease

Variations for Cervix Disease

Expression for Cervix Disease

Search GEO for disease gene expression data for Cervix Disease.

Pathways for Cervix Disease

GO Terms for Cervix Disease

Biological processes related to Cervix Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 B cell proliferation GO:0042100 8.96 CD40LG CD79A
2 protein localization to cell surface GO:0034394 8.62 FLNA MRAP

Sources for Cervix Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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