MCID: CRV002
MIFTS: 23

Cervix Uteri Carcinoma in Situ malady

Cancer category

Summaries for Cervix Uteri Carcinoma in Situ

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33MalaCards
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MalaCards: Cervix Uteri Carcinoma in Situ, also known as carcinoma in situ of uterine cervix, is related to squamous cell carcinoma and cervical intraepithelial neoplasia. An important gene associated with Cervix Uteri Carcinoma in Situ is GP6 (glycoprotein VI (platelet)), and among its related pathways are Platelet Aggregation Inhibitor Pathway, Pharmacodynamics and Formation of Fibrin Clot (Clotting Cascade). Affiliated tissues include cervix.

Aliases & Classifications for Cervix Uteri Carcinoma in Situ

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 27ICD9CM, 35MeSH, 57SNOMED-CT, 40NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer


Aliases & Descriptions:

cervix uteri carcinoma in situ 8 10
carcinoma in situ of uterine cervix 8 61
cervical intraepithelial neoplasia grade iii with severe dysplasia 8
squamous intraepithelial neoplasia, grade iii 8
cin iii - carcinoma in situ of cervix 8
severe dysplasia of the cervix uteri 8
cin iii - severe dyskaryosis 8
carcinoma in situ of cervix 8
carcinoma of cervix stage 0 8
severe dysplasia of cervix 8
malignant tumor of cervix 61
cervix ca in situ 8
cin iii 8


Related Diseases for Cervix Uteri Carcinoma in Situ

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17GeneCards, 18GeneDecks
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Diseases related to Cervix Uteri Carcinoma in Situ via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1squamous cell carcinoma10.1
2cervical intraepithelial neoplasia10.1
3adenocarcinoma in situ10.0CDKN2A
4gray platelet syndrome10.0GP5
5cervical cancer10.0CDKN2A, GP6, GP5

Graphical network of diseases related to Cervix Uteri Carcinoma in Situ:



Diseases related to cervix uteri carcinoma in situ

Clinical Features for Cervix Uteri Carcinoma in Situ

Drugs & Therapeutics for Cervix Uteri Carcinoma in Situ

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5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Cervix Uteri Carcinoma in Situ

Anatomical Context for Cervix Uteri Carcinoma in Situ

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33MalaCards
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MalaCards organs/tissues related to Cervix Uteri Carcinoma in Situ:

33
Cervix

Animal Models for Cervix Uteri Carcinoma in Situ or affiliated genes

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28inGenious Targeting Laboratory
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Publications for Cervix Uteri Carcinoma in Situ

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51PubMed
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Articles related to Cervix Uteri Carcinoma in Situ:

idTitleAuthorsYear
1
Loss of heterozygosity among tumor suppressor genes in invasive and in situ carcinoma of the uterine cervix. (11240714)
2000
2
Msh2, Mlh1, Fhit, p53, Bcl-2, and Bax expression in invasive and in situ squamous cell carcinoma of the uterine cervix. (10999751)
2000
3
Expression of bcl-2 in invasive and in situ carcinoma of the uterine cervix. (9465813)
1998
4
Small-cell neuroendocrine carcinoma of the uterine cervix associated with micro-invasive squamous cell carcinoma and adenocarcinoma in situ. (8870009)
1996
5
In situ localization of parathyroid hormone-like protein and mRNA in intraepithelial neoplasia and invasive carcinoma of the uterine cervix. (8406415)
1993
6
Invasive carcinoma of the uterine cervix following diagnosis and treatment of in situ carcinoma. Record linkage study within a National Cancer Registry. (2595011)
1989
7
Cytological criteria of the intraepithelial (in situ) carcinoma of the uterine cervix. (5230435)
1967

Genetic Variations for Cervix Uteri Carcinoma in Situ

Expression for genes affiliated with Cervix Uteri Carcinoma in Situ

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cervix Uteri Carcinoma in Situ

Search GEO for disease gene expression data for Cervix Uteri Carcinoma in Situ.

Pathways for genes affiliated with Cervix Uteri Carcinoma in Situ

Sources:
50PharmGKB, 54Reactome, 53R&D Systems
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Pathways related to Cervix Uteri Carcinoma in Situ according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8GP5, GP6
2
Hide members
9.8GP5, GP6
39.8GP5, GP6

Compounds for genes affiliated with Cervix Uteri Carcinoma in Situ

GO Terms for genes affiliated with Cervix Uteri Carcinoma in Situ

Sources:
16Gene Ontology
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Molecular functions related to Cervix Uteri Carcinoma in Situ according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1collagen bindingGO:0055189.8GP5, GP6

Products for genes affiliated with Cervix Uteri Carcinoma in Situ

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cervix Uteri Carcinoma in Situ

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet