Chagas Disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: CHG001 MIFTS: 67	Chagas Disease malady Categories: Rare diseases, Infectious diseases, Neuronal diseases
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Aliases & Classifications for Chagas Disease

Sources:
²CDC, ¹¹Disease Ontology, ¹³DISEASES, ³⁰ICD10, ³¹ICD10 via Orphanet, ³²ICD9CM, ³⁸MedlinePlus, ⁴⁸NIH Rare Diseases, ⁵⁰Novoseek, ⁵⁴Orphanet, ⁶²SNOMED-CT, ⁶⁸UMLS, ⁶⁹UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Chagas Disease:

Name: Chagas Disease ¹¹ ⁴⁸ ⁵⁴ ⁵⁰ ³⁸ ² ¹³ ⁶⁸

American Trypanosomiasis ¹¹ ⁴⁸ ⁵⁴ ²

Chagas' Disease with Digestive System Involvement ¹¹

Chagas' Disease with Nervous System Involvement ¹¹

Chagas' Disease with Other Organ Involvement ¹¹

South American Trypanosomiasis ⁴⁸

New World Trypanosomiasis ⁴⁸

Chagas' Disease ¹¹

Characteristics:

Orphanet epidemiological data:

⁵⁴

chagas disease:
Inheritance: Not applicable; Prevalence: 6-9/10000 (United States); Age of onset: All ages; Age of death: any age

Classifications:

MalaCards categories:
Global: Rare diseases, Infectious diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

ICD10: ³¹ ³⁰

Certain infectious and parasitic diseases

Protozoal diseases

Chagas disease

Chagas disease (chronic) with heart involvement

Chagas disease (chronic) with digestive system involvement

Chagas disease (chronic) with nervous system involvement

Chagas disease (chronic) with other organ involvement

Orphanet: ⁵⁴

Rare infectious diseases

External Ids:

Disease Ontology¹¹ DOID:12140

ICD9CM³² 086.2

Orphanet⁵⁴ ORPHA3386

SNOMED-CT⁶² 186817003, 54570006, 94371000119107

UMLS via Orphanet⁶⁹ C0041234

ICD10 via Orphanet³¹ B57.0, B57.1, B57.2 B57.3, B57.4, B57.5, more

ICD10³⁰ B57, B57.2 B57.3, B57.4, B57.5, more

UMLS⁶⁸ C0007932

Summaries for Chagas Disease

Sources:
²CDC, ¹¹Disease Ontology, ³⁶MalaCards, ³⁸MedlinePlus, ⁴⁸NIH Rare Diseases, ⁷¹Wikipedia
See all MalaCards sources

MedlinePlus:³⁸ Chagas disease is caused by a parasite. it is common in latin america but not in the united states. infected blood-sucking bugs, sometimes called kissing bugs, spread it. when the bug bites you, usually on your face, it leaves behind infected waste. you can get the infection if you rub it in your eyes or nose, the bite wound or a cut. the disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. if you notice symptoms, they might include fever flu-like symptoms a rash a swollen eyelid these early symptoms usually go away. however, if you don't treat the infection, it stays in your body. later, it can cause serious intestinal and heart problems. a physical exam and blood tests can diagnose it. you may also need tests to see whether the disease has affected your intestines and heart. medicines can kill the parasite, especially early on. you can also treat related problems. for example, a pacemaker helps with certain heart complications. there are no vaccines or medicines to prevent chagas disease. if you travel to areas where it occurs, you are at higher risk if you sleep outdoors or in poor housing conditions. it is important to use insecticides to prevent bites, and practice food safety. centers for disease control and prevention

MalaCards based summary: Chagas Disease, also known as american trypanosomiasis, is related to hepatitis and congestive heart failure, and has symptoms including fever, pruritus and Array. An important gene associated with Chagas Disease is TNF (Tumor Necrosis Factor), and among its related pathways are Downstream signaling in naive CD8+ T cells and OX40 Pathway. Affiliated tissues include heart, testes and eye, and related mouse phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and craniofacial.

NIH Rare Diseases:⁴⁸ Chagas disease is caused by the parasite, trypanosoma cruzi. when a triatomine bug (commonly known as a "kissing bug") infected with this parasite bites you, usually on your face, it leaves behind infected waste which can be spread into your eyes, nose, or a wound. chagas disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. symptoms can include fever, flu-like symptoms, a rash or swollen eyelid. early symptoms usually go away but if not treated, the infection can later cause serious intestinal and heart problems. chagas disease is common in latin america but not in the united states. last updated: 3/4/2014

CDC:² Chagas disease is named after the Brazilian physician Carlos Chagas, who discovered the disease in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors and is found only in the Americas (mainly, in rural areas of Latin America where poverty is widespread). Chagas disease (T. cruzi infection) is also referred to as American trypanosomiasis.

Disease Ontology:¹¹ A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.

Wikipedia:⁷¹ Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by the... more...

Related Diseases for Chagas Disease

Sources:
²⁰GeneAnalytics, ²¹GeneCards
See all MalaCards sources

Diseases related to Chagas Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 362)

id	Related Disease	Score	Top Affiliating Genes
1	hepatitis	29.7	IFNG, IL10, IL2, IL6, TNF
2	congestive heart failure	29.6	IFNG, IL10, IL2, IL6, TNF
3	neuropathy	29.6	CXCL8, IL1B, IL6, TLR4, TNF
4	trypanosomiasis	11.5
5	pyridoxal 5'-phosphate-dependent epilepsy	10.4	IL10, TNF
6	intussusception	10.4	IL1B, TNF
7	refractory celiac disease	10.4	IL10, TGFB1
8	cardiomyopathy	10.4
9	autosomal dominant deafness-onychodystrophy syndrome	10.4	IFNG, IL2, TNF
10	urethral intrinsic sphincter deficiency	10.4	CCL2, IFNG, TNF
11	neurotic disorder	10.4	IFNG, IL10, TNF
12	stocco dos santos syndrome	10.4	IFNG, IL1B, TNF
13	congenital hypothyroidism	10.3	IL10, TLR2, TNF
14	spotted fever	10.3	TLR2, TLR4, TNF
15	distal trisomy 14q	10.3	IFNG, TGFB1, TNF
16	parametritis	10.3	IFNG, IL2, TNF
17	steatitis	10.3	IL2, TNF
18	paralytic poliomyelitis	10.3	IFNG, IL2, TLR4
19	aseptic meningitis	10.3	TLR2, TLR4, TNF
20	rosacea	10.3	IFNG, IL10, IL1B
21	transient tic disorder	10.3	IL10, IL6, TNF
22	discharging ear	10.3	IFNG, IL10, TGFB1
23	parasitic ichthyosporea infectious disease	10.3	TLR2, TLR4, TNF
24	polyarteritis nodosa	10.3	IFNG, TLR2, TLR4
25	venezuelan hemorrhagic fever	10.3	IFNG, IL2, TNF
26	myeloid and lymphoid neoplasms with eosinophilia and abnormalities of pdgfra, pdgfrb, and fgfr1	10.3	CCR5, IFNG, TNF
27	idiopathic hypertrophic pachymeningitis	10.3	IL10, NOS2, TNF
28	pseudoainhum	10.3	IL1B, TLR2, TLR4
29	ethmoid sinus cancer	10.3	IFNG, IL1B, TLR4
30	conidiobolomycosis	10.3	CXCL8, IL10, TNF
31	tubular renal disease-cardiomyopathy syndrome	10.3	IL10, TNF
32	lepromatous leprosy	10.3	IFNG, IL10, IL6
33	phlyctenulosis	10.3	IL10, IL6, TNF
34	malignant oculomotor nerve tumor	10.3	CCL2, IFNG, TGFB1
35	megaloblastic anemia	10.3	IL10, IL1B, TLR4
36	reproductive system disease	10.3	IL10, IL6, TLR2
37	anal atresia, hypospadias, and penoscrotal inversion	10.3	CCL2, IFNG, TLR2
38	multiple mitochondrial dysfunctions syndrome	10.3	IFNG, IL10, IL6
39	primary ciliary dyskinesia	10.3	IL10, IL6, TNF
40	handl syndrome	10.3	CXCL8, TLR2, TNF
41	bipolar i disorder	10.3	IL1B, IL6, TNF
42	coronary arterial fistulas	10.3	CXCL8, IL10, TLR4
43	human immunodeficiency virus infectious disease	10.3	IL1B, IL6, TNF
44	measles	10.3	IL1B, IL6, TNF
45	leukoplakia of vagina	10.3	IL6, TLR2, TNF
46	endogenous depression	10.3	IL2, TLR2, TNF
47	preaxial polydactyly of fingers	10.3	IL6, TGFB1, TNF
48	dextrocardia	10.3	IL1B, IL6, TNF
49	oropharynx cancer	10.3	IFNG, IL10, IL2
50	severe combined immunodeficiency, t cell-negative, b-cell/natural killer-cell positive	10.3	IFNG, IL10, IL2, TNF

Graphical network of the top 20 diseases related to Chagas Disease:

Symptoms & Phenotypes for Chagas Disease

Sources:
²⁶GenomeRNAi, ⁴¹MGI, ⁵⁴Orphanet, ⁶⁴The Human Phenotype Ontology, ⁶⁸UMLS
See all MalaCards sources

Human phenotypes related to Chagas Disease:

⁵⁴ ⁶⁴ (show all 27)

id	Description	Orphanet Frequency	HPO Source Accession
1	edema⁵⁴	Frequent (79-30%)
2	pallor⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0000980
3	skin rash⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0000988
4	cardiomyopathy⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0001638
5	splenomegaly⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0001744
6	thromboembolism⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0001907
7	fever⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0001945
8	diarrhea⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0002014
9	abdominal pain⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0002027
10	dyspnea⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0002094
11	hepatomegaly⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0002240
12	headache⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0002315
13	lymphadenopathy⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0002716
14	myalgia⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0003326
15	localized skin lesion⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0011355
16	arrhythmia⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0011675
17	cough⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0012735
18	myocarditis⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0012819
19	autoimmune antibody positivity⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0030057
20	periorbital edema⁶⁴ ⁵⁴	Frequent (79-30%)	HP:0100539
21	congestive heart failure⁶⁴ ⁵⁴	Occasional (29-5%)	HP:0001635
22	aganglionic megacolon⁶⁴ ⁵⁴	Occasional (29-5%)	HP:0002251
23	achalasia⁶⁴ ⁵⁴	Occasional (29-5%)	HP:0002571
24	abnormal large intestine physiology⁶⁴ ⁵⁴	Occasional (29-5%)	HP:0012700
25	abnormality of the nervous system⁵⁴	Very rare (<4-1%)
26	encephalitis⁶⁴ ⁵⁴	Very rare (<4-1%)	HP:0002383
27	peripheral neuropathy⁶⁴ ⁵⁴	Very rare (<4-1%)	HP:0009830

UMLS symptoms related to Chagas Disease:

fever, pruritus

GenomeRNAi Phenotypes related to Chagas Disease according to GeneCards Suite gene sharing:

²⁶

id	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-1	7.7	CXCL8, IL10, IL1B, IL2, NOS2, TGFB1

MGI Mouse Phenotypes related to Chagas Disease according to GeneCards Suite gene sharing:

⁴¹ (show all 22)

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	craniofacial	MP:0005382	9.1	CYP51A1, IFNG, IL10, IL12B, NOS2, SMAD2
2	adipose tissue	MP:0005375	8.6	ADRB1, IL6, NOS2, TGFB1, TLR2, TLR4
3	reproductive system	MP:0005389	8.5	CCR5, IFNG, IL10, IL2, IL6, NOS2
4	vision/eye	MP:0005391	8.4	CCR5, IFNG, IL10, IL2, IL6, NOS2
5	integument	MP:0010771	8.4	IFNG, IL10, IL1B, IL6, NOS2, SMAD2
6	no phenotypic analysis	MP:0003012	8.3	ADRB1, CCR5, CYP51A1, IFNG, IL10, IL2
7	behavior/neurological	MP:0005386	8.2	CCR5, IFNG, IL10, IL2, IL6, NOS2
8	endocrine/exocrine gland	MP:0005379	8.2	ADRB1, IFNG, IL10, IL2, IL6, NOS2
9	respiratory system	MP:0005388	8.2	IFNG, IL10, IL12B, IL2, IL6, NOS2
10	liver/biliary system	MP:0005370	7.9	CCR5, IFNG, IL10, IL2, IL6, NOS2
11	neoplasm	MP:0002006	7.9	CCR5, IFNG, IL10, IL12B, IL1B, IL2
12	cellular	MP:0005384	7.8	CALR, CCR5, IFNG, IL10, IL2, IL6
13	muscle	MP:0005369	7.6	ADRB1, CALR, CCR5, CYP51A1, IFNG, IL10
14	skeleton	MP:0005390	7.5	ADRB1, CYP51A1, IFNG, IL10, IL12B, IL1B
15	digestive/alimentary	MP:0005381	7.5	CCR5, CYP51A1, IFNG, IL10, IL12B, IL2
16	hematopoietic system	MP:0005397	7.4	CCR5, IFNG, IL10, IL12B, IL1B, IL2
17	growth/size/body region	MP:0005378	7.4	ADRB1, CALR, CYP51A1, IFNG, IL10, IL2
18	nervous system	MP:0003631	7.2	CALR, CCR5, IFNG, IL10, IL1B, IL6
19	immune system	MP:0005387	7.2	CCL2, CCR5, CYP51A1, IFNG, IL10, IL12B
20	cardiovascular system	MP:0005385	6.8	ADRB1, CALR, CCR5, CYP51A1, IFNG, IL10
21	homeostasis/metabolism	MP:0005376	6.6	ADRB1, CALR, CCR5, CYP51A1, IFNG, IL10
22	mortality/aging	MP:0010768	6.5	ADRB1, CALR, CCR5, CYP51A1, IFNG, IL10

Drugs & Therapeutics for Chagas Disease

Sources:
¹BitterDB, ⁴ClinicalTrials, ¹⁰DGIdb, ¹⁴DrugBank, ²⁹HMDB, ³³IUPHAR, ⁴⁶NDF-RT, ⁵⁰Novoseek, ⁵⁶PharmGKB, ⁶⁸UMLS
See all MalaCards sources

Drugs for Chagas Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 176)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Rifampin

approved

Phase 4, Phase 3, Phase 2

348

13292-46-1

5458213, 5381226

Synonyms:

1-b]furan-21-yl acetate

13292-46-1

3-(((4-Methyl-1-piperazinyl)imino)-methyl)rifamycin

3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV

3-(4-Methylpiperazinyliminomethyl)-rifamycin SV

3-(4-Methylpiperazinyliminomethyl)rifamycin SV

3-([(4-Methyl-1-piperazinyl)imino]methyl)rifamycin SV

3-[(4-Methyl-1-piperazinyl)iminomethyl]rifamycin SV

3-[[(4-Methyl-1-piperazinyl)imino]-methyl]rifamycin

46713_FLUKA

46713_RIEDEL

62534-43-4

8-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV

8-(4-Methylpiperazinyliminomethyl) rifamycin SV

8-[[(4-Methyl-1-piperazinyl)imino[methyl]rifamycin

8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin sv

8-[[(4-Methylpiperazinyl)imino]methyl]rifamycin sv

83907_FLUKA

83907_SIGMA

8CI)

AZT + Rifampin

Abrifam

Archidyn

Arficin

Arzide

BA-41166E

BIDD:PXR0014

BPBio1_000561

BSPBio_000509

Ba 41166

Ba 41166/E

Benemicin

Benemycin

Bio-0621

C06688

C43H58N4O12

CAS-13292-46-1

CCRIS 551

CHEBI:28077

CHEBI:455936

CHEMBL180

CID5381226

CID5388984

CID5458213

CID5702112

CID6604339

CID6708473

CID6842115

CID6912767

CID6913622

CPD001906767

D00211

DB01045

DRG-0109

Dione 21-acetate

Dipicin

DivK1c_000550

Doloresum

EINECS 236-312-0

Eremfat

Famcin

Fenampicin

HMS1569J11

HMS1920P08

HMS2089F12

HMS2092G09

HMS501L12

HSDB 3181

KBio1_000550

KBio2_000919

KBio2_003487

KBio2_006055

KBio3_003018

KBioGR_001780

KBioSS_000919

L-5103

L-5103 Lepetit

LS-7689

MLS000028552

MLS001148237

MLS001333745

MolPort-000-767-051

MolPort-002-513-586

MolPort-003-666-281

MolPort-006-395-891

NCGC00016699-01

NCGC00017365-01

NCGC00018178-01

NCGC00022678-03

NCGC00022678-04

NCGC00022678-05

NCGC00160500-01

NCI60_000309

NINDS_000550

NSC 113926

NSC-113926

NSC113926

Piperine & Rifampicin

Prestwick0_000525

Prestwick1_000525

Prestwick2_000525

Prestwick3_000525

Prestwick_833

R-Cin

R/AMP

R0079

R3501_SIAL

R3501_SIGMA

R5777_SIGMA

R7382_SIGMA

RAMP

RFP

RMP

Ramp

Reserpine & Rifampicin

Rfamipicin

Rifa

Rifadin

Rifadin (TN)

Rifadin I.V

Rifadin I.V.

Rifadin IV

Rifadin Iv

Rifadin, Rimactane, Rifampicin, Rifampin

Rifadine

Rifagen

Rifaldazin

Rifaldazine

Rifaldin

Rifam

Rifamicin AMP

Rifamor

Rifampicin

Rifampicin & EEP

Rifampicin & Propolis

Rifampicin (JP15/INN)

Rifampicin SV

Rifampicin [INN:BAN:JAN]

Rifampicina

Rifampicina [INN-Spanish]

Rifampicine

Rifampicine [French]

Rifampicinum

Rifampicinum [INN-Latin]

Rifampin

Rifampin (USP)

Rifampin [USAN]

Rifamsolin

Rifamycin

Rifamycin AMP

Rifamycin Amp

Rifaprodin

Rifcin

Rifinah

Rifobac

Rifoldin

Rifoldine

Riforal

Rimactan

Rimactane

Rimactane (TN)

Rimactazid

Rimactin

Rimactizid

Rimazid

Rimycin

Rofact

S1764_Selleck

SAM002264646

SMR000058322

SMR000653525

SPBio_002430

SPECTRUM1500529

STK080143

Sinerdol

Spectrum3_001837

Spectrum4_001250

Spectrum5_002018

Spectrum_000439

TNP00313

Tubocin

UNII-VJT6J7R4TR

WLN: V1 WQ A&1 E&1 E1UN- AT6N DNTJ D1

nchembio884-comp4

rifampin

Ritonavir

approved, investigational

Phase 4, Phase 2, Phase 3

883

155213-67-5

392622

Synonyms:

1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate

155213-67-5

1hxw

1sh9

5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S)-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate

5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate

538, ABT

A-84538

ABBOTT-84538

ABT 538

ABT 84538

ABT-538

ABT538

AC-733

AC1L94GB

AKOS000280930

Abbott 84538

BIDD:GT0387

BIDD:PXR0023

Bio-0093

C07240

C37H48N6O5S2

CHEBI:45409

CHEMBL163

CID392622

CPD000466395

D00427

D019438

DB00503

DRG-0244

FT-0082824

HMS2051B08

HSDB 7160

LS-148860

MLS000759541

MLS001424063

MolPort-000-883-877

N-[(2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl]-N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-L-valinamide

NCGC00159462-02

NSC693184

Norvir

Norvir (TM)

Norvir (TN)

Norvir Sec

RIT

RTV

Ritonavir

Ritonavir (JAN/USAN/INN)

Ritonavir [USAN]

Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS.

Ritonavirum

S1185_Selleck

SAM001246783

SMR000466395

STK634209

ZINC03944422

ritonavir

Lopinavir

approved

Phase 4, Phase 2, Phase 3

344

192725-17-0

92727

Synonyms:

(1S-(1R*(R*),3R*,4R*))-N-(4-(((2,6-Dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide

(2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide

(alphaS)-Tetrahydro-N-((alphaS)-alpha-((2S,3S)-2-hydroxy-4-phenyl-3-(2-(2,6-xylyloxy)acetamido)butyl)phenethyl)-alpha-isopropyl-2-oxo-1(2H)-pyrimidineacetamide

1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-alpha-(1-methylethyl)-2-oxo-, (alphaS)- (9CI)

192725-17-0

1mui

2o4s

2q5k

2rkf

2rkg

A 157378

A 157378.0

A-157378-0

A-157378.0

AB1

ABT 157378

ABT 378

ABT-378

ABT-378, LOPINAVIR

AC1L3OPJ

AIDS032937

Aluviran

C12871

C37H48N4O5

CHEBI:40456

CHEMBL729

CID92727

D01425

DB01601

Koletra

LPV

LS-173766

Lopinavir

Lopinavir (JAN/USAN/INN)

Lopinavir [USAN:INN:BAN]

MolPort-003-848-410

N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide

N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE

NCGC00164576-01

NCGC00164576-02

RS-346

S1380_Selleck

UNII-2494G1JF75

Efavirenz

approved, investigational

Phase 4, Phase 3, Phase 2

409

154598-52-4

64139

Synonyms:

(-)-6-CHLORO-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one

(-)-Efavirenz

(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

(4S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one

(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one

(4S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one

(S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-ben

(S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

(S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one

(S)-6-chloro-4-(Cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

(S)-6-chloro-4-Cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[D][1,3]oxazin-2-one

154598-52-4

1ikv

1ikw

2H-3,1-Benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)- (9

6-chloro-4-(2-Cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[D][1,3]oxazin-2-one

6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one

AC-19049

AC1L20IX

BIDD:GT0383

C08088

C14H9ClF3NO2

CHEBI:119486

CHEMBL223228

CID64139

CPD000466351

D00896

DB00625

DB07709

DMP 266

DMP-266

EFV

EFZ

Efavirenz

Efavirenz (JAN/INN)

Efavirenzum

Eravirenz

HMS2051J08

HMS2090N16

HSDB 7163

L 743726

L-741211

L-743,726

L-743725

L-743726

LS-173464

MLS000759465

MLS001424087

Met-SDF-1.beta. & Efavirenz

Met-Stromal Cell-derived Factor-1.beta. (Human) & Efavirenz

MolPort-003-983-924

NSC742403

SAM001246667

SBB066062

SMR000466351

Stocrin

Strocin (TM)

Sustiva

Sustiva (TM)

Sustiva (TN)

UNII-JE6H2O27P8

ZINC02020233

efavirenz

efavirenz, (S)-isomer

zoxazin-2-one

Éfavirenz

Warfarin

approved

Phase 4

470

81-81-2

6691, 54678486

Synonyms:

(-)-Warfarin

(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone

(S)-Warfarin

(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin

(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine

1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone

200 Coumarin

200 coumarin

3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin

3-(Acetonylbenzyl)-4-hydroxycoumarin

3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin

3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin

3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin

4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine

4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin

4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine

4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin

4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one

4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one

4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin

4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine

4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine

4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine

45706_FLUKA

45706_RIEDEL

4oh-coumarin deriv.

5543-56-6

5543-57-7

81-81-2

A2250_FLUKA

A2250_SIGMA

AC-15978

AC1L1N37

AC1Q6AN3

AR-1E2310

Arab Rat Death

Arab rat death

Arab rat deth

Athrombin

Athrombin-K

Athrombin-k

Athrombine-K

Athrombine-k

BRD-A24514565-001-02-2

BRD-A24514565-236-01-6

BRN 1293536

BSPBio_002026

Bio-0586

Brumolin

C01541

C19H16O4

CBDivE_002127

CBDivE_013236

CBKinase1_000192

CBKinase1_012592

CHEBI:10033

CHEMBL1464

CID6691

CO-Rax

Caswell No. 903

Choice

Choice (TN)

Co-Rax

Co-rax

Compound 42

Coumadin

Coumadin Tabs

Coumafen

Coumafene

Coumafene [French]

Coumaphen

Coumaphene

Coumarins

Coumefene

Cov-R-Tox

Cov-R-tox

D-Con

D08682

DB00682

DL-3-(alpha-acetonylbenzyl)-4-hydroxycoumarin

Dethmor

Dethnel

Dicusat E

Dicusat e

DivK1c_000444

EINECS 201-377-6

EINECS 226-907-3

EPA Pesticide Chemical Code 086002

Eastern states duocide

Fasco fascrat powder

Frass-Ratron

Frass-ratron

HMS1921K07

HMS2092C20

HMS501G06

HSDB 1786

I14-0958

IDI1_000444

Jantoven

KBio1_000444

KBio2_000674

KBio2_003242

KBio2_005810

KBio3_001526

KBioGR_000901

KBioSS_000674

Killgerm sewarin p

Kumader

Kumadu

Kumatox

Kypfarin

LS-55083

Latka 42

Latka 42 [Czech]

Liqua-tox

MLS001304042

Maag Rattentod Cum

Maag rattentod cum

Mar-Frin

Mar-frin

Marevan

Martin'S mar-frin

Martin's mar-frin

Maveran

MolPort-001-787-822

Mouse pak

NCGC00094810-01

NCGC00094810-02

NCGC00159398-03

NCGC00178855-01

NINDS_000444

NSC 59813

NSC59813

PS104_SUPELCO

Panwarfin

Place-Pax

Place-pax

Prothromadin

RAX

RCR grey squirrel killer concentrate

RCRA waste no. P001

Rat & mice bait

Rat and mice bait

Rat-B-gon

Rat-Gard

Rat-Kill

Rat-Mix

Rat-O-cide #2

Rat-O-cide no. 2

Rat-Ola

Rat-Trol

Rat-a-way

Rat-alpha-way

Rat-b-gon

Rat-beta-gon

Rat-gard

Rat-kill

Rat-mix

Rat-o-cide #2

Rat-ola

Rat-trol

Ratorex

Ratox

Ratoxin

Ratron

Ratron G

Ratron g

Rats-no-more

Ratten-Koederrohr

Ratten-koederrohr

Rattenstreupulver Neu Schacht

Rattenstreupulver neu schacht

Rattenstreupulver new schacht

Rattentraenke

Rattunal

Rcra waste number P001

Ro-Deth

Ro-deth

Rodafarin

Rodafarin C

Rodafarin c

Rodex

Rodex blox

Rosex

Rough & ready mouse mix

Rough and ready mouse mix

SMP1_000316

SMR000718754

SPBio_000870

SPECTRUM1500613

STK364490

Sakarat

Sewarin

Sofarin

Solfarin

Sorexa Plus

Sorexa plus

Spectrum2_000935

Spectrum3_000583

Spectrum4_000381

Spectrum5_001751

Spectrum_000194

Spray-trol brand roden-trol

Temus W

Temus w

Tintorane

Tox-Hid

Tox-hid

Twin light rat away

UNII-5Q7ZVV76EI

Vampirinip II

Vampirinip III

Vampirinip iii

W.A.R.F. 42

WARF compound 42

WLN: T66 BOVJ DYR&1V1 EQ

Waran

Warf 10

Warf 42

Warfarat

Warfarin (INN)

Warfarin (and salts of)

Warfarin Plus

Warfarin Q

Warfarin [BSI:ISO]

Warfarin [INN:BAN]

Warfarin plus

Warfarin plus [discontinued]

Warfarin sodium

Warfarin titrated to an INR of 2.5-3.0

Warfarin(R)

Warfarina

Warfarina [INN-Spanish]

Warfarine

Warfarine [INN-French]

Warfarine [ISO-French]

Warfarinum

Warfarinum [INN-Latin]

Warficide

Warfilone

Zoocoumarin

Zoocoumarin [Netherlands and USSR]

Zoocoumarin [Russian]

delta-Con

nchembio.307-comp19

rac-Warfarin

warfarin

Emtricitabine

approved, investigational

Phase 4, Phase 3

457

143491-57-0

60877

Synonyms:

(-)-(2R,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

(-)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

(-)-.beta.-L-FTC

(-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine

(-)-2'-Deoxy-5-fluoro-3'-thiacytidine

(-)-FTC

(-)-beta-2',3'-Dideoxy-5-fluoro-3'-thiacytidine

(-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine

(-)-cis-4-amino-5-Fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one

(-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one

(2R-cis)-4-Amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone

(2R-cis)-4-amino-5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone

.beta.-L-(-)-(2R,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

1-(2-(Hydroxymethyl)oxathiolan-5-yl)-5-fluorocytosine

143491-54-7

143491-57-0

145213-48-5

2',3',5-FTC

2',3'-Dideoxy-5-fluoro-3'-thiacytidine

2'-Deoxy-5-fluoro-3'-oxa-4'-thiocytidine

2'-Deoxy-5-fluoro-3'-thiacytidine

2-FTC

3'-Thia-2'.3'-dideoxy-5-fluorocytidine

4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one

4-Amino-5-fluoro-1-[(2R,5S)-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

4-amino-5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one

4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine

5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine

5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)[1,3]oxathiolan-5-yl]cytosine

524W91

AC1L1U3I

AC1Q4KUB

BW 1592

BW 524W91

BW-524W91

BW524W91

C122114

C12599

C8H10FN3O3S

CHEBI:31536

CHEMBL885

CID60877

Coviracil

Coviracil(TM)

D01199

DB00879

DRG-0208

Emtricitabin

Emtricitabina

Emtricitabine

Emtricitabine (JAN/USAN/INN)

Emtricitabinum

Emtriva

Emtriva (TN)

Emtriva(TM)

FT-0080009

HMS2089I05

HSDB 7337

LS-135838

LS-173184

NCGC00164564-01

RCV

Racivir

SBB066061

TL8000958

UNII-G70B4ETF4S

ZINC03629271

beta-L-2',3'-dideoxy-5-fluoro-3'-thiacytidine

dOTFC

emtricitabine

Ethambutol

approved

Phase 4, Phase 3, Phase 2

74-55-5

3279, 14052

Synonyms:

(+)-(S,S)-2,2'-(1,2-Ethylenediimino)-di-1-butanol

(+)-2,2'-(Ethylenediimino)di-1-butanol

(+)-2,2'-(ethylenediimino)di-1-butanol

(+)-N,N'-Bis(1-(hydroxymethyl)propyl)ethylenediamine

(+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine

(+)-S,S-Ethambutol

(+)-S,S-ethambutol

(+)-ethambutol

(-)-(R,R)-2,2'-(1,2-Ethylenediimino)-di-1-butanol

(2'S)-2,2'-[Ethane-1,2-diyldi(imino)]dibutan-1-ol

(2R)-2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol

(2R)-2-[2-[[(2R)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol

(2S)-2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol

(2S)-2-[2-[[(2R)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol

(2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol

(2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol

(2S,7S)-2,7-Diethyl-3,6-diazaoctane-1,8-diol

(2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol

(R)-2,2'-(1,2-Ethanediyldiimino)bis-1-butanol

(S,R)-2,2'-(1,2-Ethylenediimino)-di-1-butanol

(S,S)-Ethambutol

(S,S)-ethambutol

1070-11-7

2,2'-(1,2-Ethylenediimino)-di-1-butanol

2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol

2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol

74-55-5

75343-56-5

AC1L1FKQ

AC1L230T

AC1L9YT2

AC1LABPH

AC1LAKIP

AC1LAKIS

AC1Q2C85

AC1Q2SHV

AC1Q77PZ

AR-1A7805

AR-1C2065

Aethambutolum

BPBio1_000105

BSPBio_000095

BSPBio_002012

C06984

C10H24N2O2

CAS-1070-11-7

CHEBI:4877

CHEMBL43824

CHEMBL44884

CID14052

CID3279

CID465436

CID470071

CID470072

CID504259

CL 40881 (dihydrochloride)

CPD000046147

D-2,2'-(Ethylenediimino)bis(1-butanol)

D-2,2'-(Ethylenediimino)di-1-butanol

D-Ethambutol

D-N,N'-Bis(1-hydroxymethylpropyl)ethylenediamine

D07925

DB00330

Dadibutol

Diambutol

DivK1c_000561

EINECS 200-810-6

EMB

Etambutol

Etambutol [INN-Spanish]

Etambutolo

Etambutolo [DCIT]

Ethambutol

Ethambutol & EEP

Ethambutol & Propolis

Ethambutol (INN)

Ethambutol HCL

Ethambutol Hydrochloride

Ethambutol [INN:BAN]

Ethambutol dihydrochloride

Ethambutol, (-)-isomer

Ethambutol, meso form

Ethambutol, racemic mixture

Ethambutolum

Ethambutolum [INN-Latin]

Etibi

HSDB 3078

IDI1_000561

KBio1_000561

KBio2_001538

KBio2_004106

KBio2_006674

KBio3_001232

KBioGR_001209

KBioSS_001538

KST-1A8084

LS-187119

LS-46537

MLS000082702

Miambutol

MolPort-002-507-956

MolPort-003-847-110

Myambutol

Myambutol (dihydrochloride)

NCGC00016560-01

NCGC00178864-01

NCGC00179661-01

NINDS_000561

NSC653313

Prestwick0_000028

Prestwick1_000028

Prestwick2_000028

Prestwick3_000028

Purderal

S,S-Ethambutol

SAM002589988

SMR000046147

SPBio_001167

SPBio_002016

STK711105

STOCK5S-98432

Servambutol

Servambutol (TN)

Spectrum2_001014

Spectrum3_000426

Spectrum4_000545

Spectrum5_000702

Spectrum_001058

Tibutol

UNII-8G167061QZ

d,N,N'-Bis(1-hydroxymethylpropyl)ethylenediamine

ethambutol

Lamivudine

approved, investigational

Phase 4, Phase 3, Phase 2

621

134678-17-4

60825

Synonyms:

(+/-) (Cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

(+/-)-3TC

(+/-)-BCH-189

(+/-)-SddC

(-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine

(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine

(-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

(-)-2'-Deoxy-3'-thiacytidine

(-)-BCH 189

(-)-BCH-189

(-)-SddC

(-)-beta-L-2',3'-Dideoxy-3'-thiacytidine

(-)NGPB-21

(2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one

.beta.-L-(-)-2',3'-dideoxy-3'-thiacytidine & Sho-Saiko-To

134678-17-4

2',3' Dideoxy 3' thiacytidine

2',3'-Dideoxy-3'-thiacytidine

2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (+/-) (Cis)

2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S)

2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Galanthus Nivalis Agglutinin (GNA)

2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Hippeastrum hybrid agglutinin( HHA)

3'-Thia-2',3'-dideoxycytidine

3TC

3TC & GNA

3TC & SST

3TC (AIDS INITIATIVE) (AIDS INITIATIVE)

3TC and NV-01

3TC, Zeffix, Heptovir, Epivir, Epivir-HBV, Lamivudine

4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone

4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one

4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

480434-79-5

AC-1416

AC1L1TZZ

AC1Q6C34

BCH 189

BCH-189

BCH-790

BCH189

BIDD:GT0033

Bio-0652

C07065

C8H11N3O3S

CCRIS 9274

CHEBI:133986

CHEMBL141

CID60825

CPD000466319

D00353

D019259

DB00709

DRG-0126

DTHC

Epivir

Epivir (TN)

Epivir(TM)

Epivir-HBV

Epzicom

FT-0082667

GG-714

GR 109714X

GR-109714X

GR109714X

HHA & 3TC

HHA & Lamivudine

HMS2051D21

HSDB 7155

Hepitec

Heptivir

Heptodin

Heptovir

L0217

LMV

LS-2107

Lamivir

Lamivudin

Lamivudina

Lamivudine

Lamivudine & GNA

Lamivudine (JAN/USP/INN)

Lamivudine [USAN:BAN:INN]

Lamivudine [USAN:INN:BAN]

Lamivudine [Usan:Ban:Inn]

Lamivudine, (2S-cis)-Isomer

Lamivudinum

MLS000759424

MLS001424097

MolPort-002-507-347

NCGC00159341-03

NCGC00159341-04

NSC620753

S1706_Selleck

SAM001246582

SAM002589994

SMR000466319

STK801940

UNII-2T8Q726O95

ZINC00012346

Zeffix

Zefix

beta-L-2',3'-Dideoxy-3'-thiacytidine

beta-L-3'-Thia-2',3'-dideoxycytidine

lamivudine

Zidovudine

approved

Phase 4, Phase 3, Phase 2

495

30516-87-1

35370

Synonyms:

-Azido-3&prime

-deoxythymidine

1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)thymine

3&prime

3' Azido 2',3' Dideoxythymidine

3' Azido 3' deoxythymidine

3'-Azido-2',3'-Dideoxythymidine

3'-Azido-3'-deoxythymidine

3'-Azido-3'-deoxythymidine & Concanavalin A

3'-Azido-3'-deoxythymidine & Erythropoietin

3'-Azido-3'-deoxythymidine & Heteropolyoxotungstate PM-19

3'-Azido-3'-deoxythymidine & Interleukin-1

3'-Azido-3'-deoxythymidine & Interleukin-2

3'-Azido-3'-deoxythymidine & Interleukin-6

3'-Azido-3'-deoxythymidine & Lithium & Erythropoietin

3'-Azido-3'-deoxythymidine & Lithium & Interleukin-1

3'-Azido-3'-deoxythymidine & Lithium & Interleukin-6

3'-Azido-3'-deoxythymidine & Lymphoblastoid Interferon

3'-Azido-3'-deoxythymidine & Sho-Saiko-To

3'-Azido-3'-deoxythymidine (AIDS)

3'-Azido-3'deoxythymidine & Interferon .alpha.

3'-Azidothymidine

3'-Deoxy-3'-azidothymidine

3'-azido-3'-deoxythymidine, AZT

3-Azido-3-deoxythymidine

30516-87-1

399024-19-2

A2169_SIGMA

AC1L1TKL

AC1Q2OEK

AZT

AZT & CD4(178)-PE 40

AZT & Colony-stimulating factor 2

AZT & Concanavalin A (ConA)

AZT & EPO

AZT & GM-CSF

AZT & HPA

AZT & IFN.alpha.

AZT & IL-1

AZT & IL-2

AZT & IL-6

AZT & Interferon-.alpha.-2

AZT & Li & EPO

AZT & Li & GM-CSF

AZT & Li & IL-1

AZT & Li & IL-6

AZT & Lymphoblastoid Interferon

AZT & NP (from PHCA or HSA)

AZT & PM-19

AZT & SST

AZT & rIFN.alpha.2

AZT & rsCD4 & rIFN.alpha.A

AZT & rsT4

AZT & sCD4

AZT & srCD4

AZT (Antiviral)

AZT Antiviral

AZT TRANSPLACENTAL CARCINOGENESIS STUDY

AZT+PRO 140

AZT, Antiviral

Antiviral AZT

Apo-Zidovudine

Azidothymidine

Aztec

BB_NC-1012

BPBio1_000403

BRD-K72903603-001-04-6

BSPBio_000365

BSPBio_003153

BW A509U

BW-A 509U

BW-A-509U

BW-A509U

BWA 509U

BWA-509U

BWA509U

C07210

CCRIS 105

CHEBI:10110

CHEBI:127307

CHEMBL129

CID35370

CPD000058351

Compound S

Cpd S

D00413

D015215

DB00495

DRG-0004

DS-4152 & AZT

DivK1c_000524

HMS1921J20

HMS2090G11

HMS2092D06

HMS501K06

HSDB 6515

IDI1_000524

Interferon AD + 3'-azido-3'-deoxythymidine

Intron A & AZT

K7 [P Ti2 W10 O40]

KBio1_000524

KBio2_001828

KBio2_004396

KBio2_006964

KBio3_002653

KBioGR_000703

KBioSS_001828

LS-1159

Liposomal AZT-SN-1

Liposomal AZT-SN-3

MLS000028548

MLS001055351

MLS001076358

MLS002153202

MLS002222249

Met-SDF-1.beta. & AZT

Met-SDF-1.beta. & Zidovudine

MolPort-002-507-286

NCGC00023945-03

NCGC00023945-04

NCGC00023945-05

NCGC00023945-08

NCGC00178237-01

NCGC00178237-02

NINDS_000524

NSC 602670

Novo-Azt

PC-SOD+AZT

Prestwick3_000333

Propolis+AZT

Racemic Liposomal AZT

Retrovir

Retrovir (TN)

Retrovir(TM)

SAM002548971

SMR000058351

SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle)

SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle)

SPBio_000834

SPECTRUM1502109

STK801891

Spectrum2_000927

Spectrum3_001507

Spectrum4_000332

Spectrum5_001101

Spectrum_001348

UNII-4B9XT59T7S

ZDV

ZIDOVUDINE [AZT]

ZINC03779042

ZVD

Zidovudin

Zidovudina

Zidovudina [Spanish]

Zidovudine (JAN/USP/INN)

Zidovudine EP III

Zidovudine [USAN:INN:BAN:JAN]

Zidovudine+PRO 140

Zidovudinum

Zidovudinum [Latin]

antiviral

azidodeoxythymidine

rIFN-beta seron & AZT

racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle)

zidovudin

zidovudine

Didanosine

approved

Phase 4, Phase 3

150

69655-05-6

50599

Synonyms:

149409-57-4

2',3'-Dideoxyinosine

2',3'-Dideoxyinosine & Granulocyte-macrophage colony-stimulating factor

2',3'-Dideoxyinosine & Interferon-.alpha.

2',3'-Dideoxyinosine & sCD4(soluble recombinant protein)

2',3'-Dideoxyinosine (AIDS Initiative)

2',3'-Dideoxyinosine (ddI)

2',3'-dideoxyinosine, DDI, NSC 612049, Didanosine

2'3'-DIDEOXYINOSINE

2,3-Dideoxyinosine

2,3-dideoxyinosine

2DI

3'-Azido-3'-deoxythymidine + 2',3'-Dideoxyinosine

69655-05-6

9-((2R,5S)-5-(Hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one

9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one

9-((2R,5S)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one

9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ol

9-(2,3-Dideoxy-beta-D-ribofuranosyl)-6-oxopurine

9-(2,3-Dideoxy-beta-D-ribofuranosyl)hypoxanthine

9-[(2R,5R)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL]-1,9-DIHYDRO-6H-PURIN-6-ONE

9-[(2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one

9-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one

9-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one

AC-12026

AC1L19ET

AC1L3OPK

BMY 40900

BMY-40900

BRN 3619529

Benzeneethanamine, 4-methoxy-3-(2-phenylethoxy)-N,N-dipropyl-, hydrochloride

Bio-0685

C06953

C083832

CCRIS 805

CHEBI:490877

CHEMBL1460

CID119381

CID50599

CPD000058576

D00296

D2I

D3066

DB00900

DB02392

DDI

DDI and rIFN.alpha.2

DIDEOXYINOSINE

DRG-0016

DS-4152 & ddI

DdIno

Didanosina

Didanosina [INN-Spanish]

Didanosine

Didanosine (JAN/USAN/INN)

Didanosine and Interferon-.alpha.-2

Didanosinum

Didanosinum [INN-Latin]

Dideoxyinosine

Dideoxyinosine (DDI)

FT-0082664

HMS2051J11

HMS2089N20

HSDB 6548

Hypoxanthine ddN

Inosine, 2',3'-dideoxy- & Recombinant Interferon-.alpha.-2

Intron A & Videx

KS-1049

LOA & ddI

Listera ovata agglutinin & 2',3'-Dideoxyinosine

MLS000759469

MLS001055350

MLS001424118

MLS002154216

MolPort-002-507-371

MolPort-002-885-819

N,N-Dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride

N,N-diethyl-2-(4-methoxy-3-phenethyloxyphenyl)ethanamine hydrochloride

NCGC00090691-01

NCGC00159514-02

NCGC00159514-03

NCGC00164280-01

NE 100

NE-100

NSC 612049

NSC-612049

NSC612049

PC-SOD+ddI

S1702_Selleck

SAM001246673

SMR000058576

Sulfated polysaccharide-peptidoglycan DS-4152 & 2',3'-Dideoxyinosine

UNII-K3GDH6OH08

Videx

Videx (TN)

Videx EC

Videx EC(TM)(slow-release capsules)

Videx(TM)

ZINC13597823

ddI & GM-CSF

ddI & IFN-.alpha.

ddI & sCD4(rsCD4)

ddI + d4T combination

ddIno

didanosine

Pyrazinamide

approved

Phase 4, Phase 3, Phase 2

98-96-4

1046

Synonyms:

2-Carbamylpyrazine

2-Pyrazinecarboxamide

2-carbamyl pyrazine

2-carbamylpyrazine

2-pyrazinecarboxamide

5-25-04-00178 (Beilstein Handbook Reference)

82612_FLUKA

98-96-4

AB00052083

AC-907/25014068

AC1L1ALT

AC1Q4ZGM

AKOS000120280

AZT + Pyrazinamide combination

Aldinamid

Aldinamide

BB_SC-1250

BIDD:GT0228

BPBio1_000515

BRN 0112306

BSPBio_000467

BSPBio_002572

Braccopiral

C01956

C5H5N3O

CAS- 98-96-4

CCRIS 545

CHEBI:45285

CHEMBL614

CID1046

CPD000036662

Corsazinmid

D-50

D-50 (VAN)

D00144

D011718

DB00339

DRG 0124

Dipimide

DivK1c_000241

EINECS 202-717-6

EU-0101011

Eprazin

Farmizina

HMS1569H09

HMS1920N08

HMS2092E09

HMS500M03

HSDB 3576

I14-6758

IDI1_000241

InChI=1/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9

Isopas

KBio1_000241

KBio2_001382

KBio2_003950

KBio2_006518

KBio3_001792

KBioGR_001851

KBioSS_001382

LS-2053

Lopac-P-7136

Lopac0_001011

Lynamide

MK 56

MLS000069730

MLS002222347

MolPort-001-770-770

NCGC00015833-01

NCGC00015833-02

NCGC00015833-05

NCGC00015833-10

NCGC00090695-01

NCGC00090695-03

NCGC00090695-04

NCGC00090695-05

NCGC00090695-06

NCGC00090695-07

NCI-C01785

NINDS_000241

NSC 14911

NSC14911

Novamid

P 7136

P ezetamid

P0633

P7136_SIGMA

PZA

Pezetamid

Pharozinamide

Piraldina

Pirazimida

Pirazinamid

Pirazinamida

Pirazinamida [INN-Spanish]

Pirazinamide

Pirazinamide [DCIT]

Pirilene

Prazina

Prestwick0_000514

Prestwick1_000514

Prestwick2_000514

Prestwick3_000514

Prestwick_811

Pyrafat

Pyramide

Pyrazide

Pyrazinamdie

Pyrazinamid

Pyrazinamida

Pyrazinamide

Pyrazinamide (JP15/USP/INN)

Pyrazinamide (TN)

Pyrazinamide BP 2000

Pyrazinamide [INN:BAN:JAN]

Pyrazinamidum

Pyrazinamidum [INN-Latin]

Pyrazine carboxamide

Pyrazine carboxylamide

Pyrazineamide

Pyrazinecarboxamide

Pyrazinecarboxylic acid amide

Pyrazinoic acid am ide

Pyrazinoic acid amide

Pyrazinoic acid amide, Pezetamid, Pyrafat, Zinamide, Tebrazid, Pyrafat, Pyrazinamide

Pyrizinamide

Rifater

Rozide

S1762_Selleck

SAM002554927

SMR000036662

SPBio_001369

SPBio_002388

SPECTRUM1500518

STK801661

Spectrum2_001305

Spectrum3_001046

Spectrum4_001186

Spectrum5_001026

Spectrum_000902

T 165

Tebrazid

Tebrazio

Tisamid

UNII-2KNI5N06TI

Unipyranamide

WLN: T6N DNJ BVZ

ZINC00002005

Zinamide

Zinastat

pms-Pyrazinamide

pyrazinamide

pyrazine carboxylamide

pyrazine-2-carboxamide

pyrazinecarboxamide

pyrazinoic acid amide

Isoniazid

approved

Phase 4, Phase 3, Phase 2

155

54-85-3

3767

Synonyms:

37271-10-6

4-pyridinecarbohydrazide

41466-07-3

5015 R.P

5015 R.P.

5015 RP

54-85-3

62229-51-0

7640-37-1

AB00052025

AC1L1GNZ

AC1Q54UP

AC1Q54UQ

AI3-23936

AKOS000119062

AZT + Isoniazid

Abdizide

Andrazide

Anidrasona

Antimicina

Antituberkulosum

Armacide

Armazid

Armazide

Atcotibine

Azuren

BB_SC-6246

BIDD:GT0140

BP 5015

BPBio1_000025

BPBio1_001322

BSPBio_000021

BSPBio_002204

Bacillin

Biomol-NT_000288

C07054

C6H7N3O

CAS-54-85-3

CCRIS 351

CHEBI:6030

CHEMBL64

CID3767

CPD000059082

Cedin

Cedin (Aerosol)

Cemidon

Chemiazid

Chemidon

Continazine

Cortinazine

Cotinazin

Cotinizin

D00346

D007538

DB00951

Defonin

Dibutin

Diforin

Dinacrin

Ditubin

DivK1c_000070

Dow-Isoniazid

EINECS 200-214-6

Ebidene

Eralon

Ertuban

Eutizon

Evalon

FRS-3

FSR 3

FSR-3

Fetefu

Fimalene

GINK

HIA

HMS1568B03

HMS1920H09

HMS2089I16

HMS2091N19

HMS500D12

HSDB 1647

Hid rasonil

Hidranizil

Hidrasonil

Hidrulta

Hidrun

Hycozid

Hydra

Hydrazid

Hydrazide

Hyozid

Hyzyd

I.A.I

I.A.I.

I0138

I14-9731

I3377_FLUKA

I3377_SIGMA

IDI1_000070

INH

INHd20

Ido-tebin

Idrazil

In-73

Inah

Inh-Burgthal

Inizid

Iscotin

Isidrina

Ismazide

Isobicina

Isocid

Isocidene

Isocotin

Isohydrazide

Isokin

Isolyn

Isonerit

Isonex

Isoniacid

Isoniazid

Isoniazid & EEP

Isoniazid & Propolis

Isoniazid SA

Isoniazida

Isoniazide

Isoniazidum

Isonicazide

Isonicid

Isonico

Isonicotan

Isonicotil

Isonicotinhydrazid

Isonicotinic acid hydrazide

Isonicotinic hydrazide

Isonicotinohydrazide

Isonicotinoyl hydrazide

Isonicotinoylhydrazide

Isonicotinsaeurehydrazid

Isonicotinyl hydrazide

Isonicotinyl hydrazine

Isonicotinylhydrazine

Isonide

Isonidrin

Isonikazid

Isonilex

Isonin

Isonindon

Isonirit

Isoniton

Isonizida

Isonizide

Isopyrin

Isotamine

Isotebe

Isotebezid

Isotinyl

Isozid

Isozide

Isozyd

KBio1_000070

KBio2_001333

KBio2_003901

KBio2_006469

KBio3_001424

KBioGR_000423

KBioSS_001333

L 1945

LANIZID

LS-205

Laniazid

Laniazid (TN)

Laniozid

MLS000069444

MLS001055327

MolPort-000-141-557

Mybasan

NCGC00016244-01

NCGC00016244-02

NCGC00022648-03

NCGC00022648-04

NCGC00022648-05

NCGC00022648-06

NINDS_000070

NSC 9659

NSC9659

Neo-Tizide

Neoteben

Neoxin

Neumandin

Nevin

Niadrin

Nicazide

Nicetal

Nicizina

Niconyl

Nicotibina

Nicotibine

Nicotisan

Nicozide

Nidaton

Nidrazid

Nikozid

Niplen

Nitadon

Niteban

Nitebannsc 9659

Nydrazid

Nyscozid

Oprea1_396155

Pelazid

Percin

Phthisen

Preparation 6424

Prestwick0_000161

Prestwick1_000161

Prestwick2_000161

Prestwick3_000161

Prestwick_578

Pycazide

Pyreazid

Pyricidin

Pyridicin

Pyridine-4-carboxylic acid hydrazide

Pyrizidin

RP 5015

RP-5015

RU-EF-Tb

RY-EF-Tb

Raumanon

Razide

Retozide

Rifamate

Rimicid

Rimifon

Rimiphone

Rimitsid

Robiselin

Robisellin

Roxifen

S1937_Selleck

SAM002554904

SMR000059082

SPBio_000094

SPBio_001942

SPECTRUM1500355

STK086288

Sanohidrazina

Sauterazid

Sauterzid

Spectrum2_000107

Spectrum3_000472

Spectrum4_000022

Spectrum5_000876

Spectrum_000853

Stanozide

TB-Phlogin

TB-Razide

TB-Vis

Tebecid

Tebenic

Tebexin

Tebilon

Tebos

Teebaconin

Tekazin

Tibazide

Tibemid

Tibiazide

Tibinide

Tibison

Tibivis

Tibizide

Tibusan

Tisin

Tisiodrazida

Tizide

Tubazid

Tubazide

Tubeco

Tubecotubercid

Tuberian

Tubicon

Tubilysin

Tubizid

Tubomel

Tyvid

UNII-V83O1VOZ8L

Unicocyde

Unicozyde

Usaf cb-2

Vazadrine

Vederon

WLN: T6NJ DVMZ

ZINC00001590

Zidafimia

Zinadon

Zonazide

bacillen

bp 5 015

isoco tin

isoniazid

isozid e

nchembio884-comp3

nidra zid

rimif on

tebemid

tubercid

Enalaprilat

approved

Phase 4

124

76420-72-9

6917719

Synonyms:

(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid

(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid dihydrate

1-((2S)-2-{[(1S)-1-CARBOXY-3-PHENYLPROPYL]AMINO}PROPANOYL)-L-PROLINE

1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate

76420-72-9

AC1NUWEA

AC1OCEK7

BIDD:GT0752

C11720

C18H24N2O5.2H2O

CHEBI:116759

CHEBI:42302

CHEBI:4786

CHEBI:59877

CHEMBL1200697

CHEMBL577

CID5462501

CID6917719

CPD000466359

D03769

EAL

ENALAPRILAT INHIBITOR

Enalapril acid

Enalapril diacid

Enalaprilat

Enalaprilat (USP)

Enalaprilat anhydrous

Enalaprilate

Enalaprilatum

Enalaprilic acid

Enalprilate hydrate

HMS2051H16

HMS2089P04

LS-118903

LS-187219

MK-422

MLS000759476

MLS001424138

MolPort-005-943-792

N-[(1S)-1-Carboxy-3-phenylpropyl]-L-alanyl-L-proline

N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline

N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline--water (1/2)

N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline—water (1/2)

NCGC00164593-01

S1657_Selleck

SAM001246684

SBB065733

SMR000466359

Vasotec I.V.

enalaprilat dihydrate

enalaprilat hydrate

enalprilat hydrate

enalprilate hydrate

Tenofovir

approved, investigational

Phase 4, Phase 3, Phase 2

759

147127-20-6

464205

Synonyms:

(R)-9-(2-Phosphonomethoxypropyl)adenine

(R)-9-(2-Phosphonylmethoxypropyl)adenine

(R)-9-(2-phosphonomethoxypropyl)adenine

(R)-PMPA

147127-20-6

206184-49-8

AC-760

AC1LA9BO

Anh. tenofovir

Anhydrous tenofovir

Apropovir

CHEBI:45809

CHEMBL483

CID464205

D,L-Tenofovir

DB00300

GNA & Tenofovir

GS 1275

GS 1278

GS1278

HHA & Tenofovir

KS-5021

MolPort-003-850-411

NCGC00167535-01

PMPA

PMPA-(R)

Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Galanthus nivalis agglutinin (GNA)

Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Hippeastrum hybrid agglutinin( HHA)

Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- (9CI)

Phosphonic acid, [[2-(6-amino-9H-purin-9

S1401_Selleck

TDF

TFV

Tenefovir

Tenofovir

Tenofovir (anh.)

Tenofovir disoproxil

Tenofovir disoproxil fumarate

UNII-99YXE507IL

Viread

Viread, Tenofovir

[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid

Enalapril

approved, vet_approved

Phase 4

124

75847-73-3

5362032, 40466924

Synonyms:

(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid

(S)-1-(N-(1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline

(S)-1-{(S)-2-[1-((S)-ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid

1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester

75847-73-3

AC1NTUS5

Analapril

BIDD:GT0751

BPBio1_000340

BSPBio_000308

BSPBio_003035

Bonuten

C06977

CAS-76095-16-4

CHEBI:116847

CHEBI:4784

CHEMBL578

CID5388962

D07892

DivK1c_000408

Enalapril

Enalapril (INN)

Enalapril (TN)

Enalapril Bp

Enalapril Maleate

Enalapril Richet

Enalaprila

Enalaprila [INN-Spanish]

Enalaprilat

Enalaprilum

Enalaprilum [INN-Latin]

Gadopril

HMS2090E08

IDI1_000408

KBio1_000408

KBio2_001787

KBio2_004355

KBio2_006923

KBio3_002535

KBioGR_000355

KBioSS_001787

Kinfil

LS-190651

MolPort-002-885-877

N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline

N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl-L-proline

NCGC00016932-01

NCGC00021569-04

NCGC00021569-05

NCGC00021569-06

NINDS_000408

Prestwick3_000314

SPBio_001349

Spectrum2_001455

Spectrum3_001478

Spectrum4_000008

Spectrum5_001107

Spectrum_001307

Vaseretic

Vasotec

Vasotec IV

enalapril

Carvedilol

approved, investigational

Phase 4

168

72956-09-3

2585

Synonyms:

(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol

(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol

(+-)-1-Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol

(+/-)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol

1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol

1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol

1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol

1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol

107741-96-8

72956-09-3

AB1004830

AC-1641

AC1L1E0B

Artist

Artist (TN)

Atlana Pharma brand of carvedilol

BM 14190

BM-14-190

BM-14.190

BM-14190

BRD-A10977446-001-04-8

BRD-A10977446-045-01-1

Bio-0014

C043211

C06875

C2260

C24H26N2O4

CHEBI:3441

CHEMBL723

CID2585

CPD000449280

Carvedilol

Carvedilol (JAN/USAN/INN)

Carvedilol [USAN:INN:BAN:JAN]

Carvedilolum

Carvedilolum [Latin]

Coreg

Coreg (TN)

Coreg CR

Coropres

Coropress

D00255

DB01136

DQ 2466

DQ-2466

Dibloc

Dilatrend

EG-P042

Eucardic

GlaxoSmithKline brand of carvedilol

HMS2051N03

HMS2089B09

HMS2093E12

HSDB 7044

I06-0064

I06-1477

KBio2_002145

KBio2_004713

KBio2_007281

KBio3_002323

KBioGR_001252

KBioSS_002145

Kredex

L001243

LS-121875

Lakeside brand of carvedilol

MLS000758299

MLS000759508

MLS001424092

MolPort-003-666-814

NCGC00167832-01

NCGC00167832-02

NCGC00167832-03

Querto

Roche brand of carvedilol

SAM001246736

SAM001247021

SK&F-105517

SKF 105517

SMR000449280

SPBio_001885

STK621453

Spectrum2_001673

Spectrum3_001182

Spectrum4_000636

Spectrum5_001436

Spectrum_001665

TL8005080

UNII-0K47UL67F2

carvedilol

carvedilol, (+-)-isomer

carvedilol, (R)-isomer

carvedilol, (S)-isomer

carvedilol, 14C-labeled

Aspirin

approved, vet_approved

Phase 4

1152

50-78-2

2244

Synonyms:

11126-35-5

11126-37-7

1oxr

2-(Acetyloxy)benzoate

2-(Acetyloxy)benzoic acid

2-Acetoxybenzenecarboxylic acid

2-Acetoxybenzoate

2-Acetoxybenzoic acid

2-Carboxyphenyl acetate

2349-94-2

26914-13-6

50-78-2

8-hour Bayer

98201-60-6

A 5376

A.S.A

A.S.A.

A.S.A. Empirin

A.S.A. empirin

A2093_SIGMA

A3160_SIGMA

A5376_SIGMA

A6810_SIGMA

AB1003266

AC 5230

AC1L1D8U

AC1Q1LA0

ACETYLSALICYLIC ACID

AI3-02956

AIN

AKOS000118884

ASA

Acenterine

Acesal

Acetal

Acetard

Aceticyl

Acetilsalicilico

Acetilum acidulatum

Acetisal

Acetol

Acetonyl

Acetophen

Acetosal

Acetosalic acid

Acetosalin

Acetoxybenzoic acid

Acetylin

Acetylsal

Acetylsalicylate

Acetylsalicylic acid

Acetylsalicylsaeure

Acetylsalicylsaure

Acetylsalicylsäure

Acetylsalycilic acid

Acetyonyl

Acetysal

Acetysalicylic acid

Acide acetylsalicylique

Acido O-acetil-benzoico

Acido acetilsalicilico

Acidum acetylsalicylicum

Acimetten

Acisal

Acylpyrin

Adiro

Aloxiprimum

Asacard

Asagran

Asatard

Ascoden-30

Aspalon

Aspec

Aspergum

Aspir-Mox

Aspirdrops

Aspirin

Aspirin (JP15/USP)

Aspirin [BAN:JAN]

Aspirina 03

Aspirine

Asprin

Aspro

Aspro Clear

Asteric

Azetylsalizylsaeure

Azetylsalizylsäure

BIDD:GT0118

BRN 0779271

Bay-e-4465

Bayer

Bayer Aspirin 8 Hour

Bayer Buffered

Bayer Extra Strength Aspirin For Migraine Pain

Bayer Plus

Benaspir

Bi-prin

Bialpirina

Bialpirinia

Bufferin

C01405

CCRIS 3243

CHEBI:15365

CHEMBL25

CID2244

Caprin

Cardioaspirin

Cardioaspirina

Cemirit

Claradin

Clariprin

Colfarit

Contrheuma retard

Coricidin

Crystar

D00109

D001241

DB00945

Decaten

Delgesic

Dispril

DivK1c_000555

Dolean pH 8

Duramax

ECM

EINECS 200-064-1

EU-0100038

Easprin

Easprin (TN)

Ecolen

Ecotrin

Empirin

Empirin with Codeine

Endosprin

Endydol

Entericin

Enterophen

Enterosarein

Enterosarine

Entrophen

Extren

Globentyl

Globoid

HMS1920E13

HMS2090G03

HMS2091K13

HMS501L17

HSDB 652

Helicon

I14-7505

IDI1_000555

Idragin

Istopirin

KBio1_000555

KBio2_001725

KBio2_002271

KBio2_004293

KBio2_004839

KBio2_006861

KBio2_007407

KBio3_002149

KBio3_002751

KBioGR_000398

KBioGR_002271

KBioSS_001725

KBioSS_002272

Kapsazal

Kyselina 2-acetoxybenzoova

Kyselina acetylsalicylova

LS-143

Levius

Lopac-A-5376

Lopac0_000038

MLS001055329

MLS001066332

MLS001336045

MLS001336046

Magnecyl

Measurin

Medisyl

Micristin

MolPort-000-871-622

NCGC00015067-01

NCGC00015067-04

NCGC00015067-09

NCGC00090977-01

NCGC00090977-02

NCGC00090977-03

NCGC00090977-04

NCGC00090977-05

NCGC00090977-06

NCGC00090977-07

NCI60_002222

NINDS_000555

NSC 27223

NSC27223

NSC406186

Neuronika

Novid

Nu-seals

Nu-seals aspirin

O-(Acetyloxy)benzoate

O-(Acetyloxy)benzoic acid

O-Acetoxybenzoate

O-Acetoxybenzoic acid

O-Acetylsalicylic acid

O-Carboxyphenyl acetate

O-accetylsalicylic acid

O-acetylsalicylic acid

PL-2200

Persistin

Pharmacin

Pirseal

Polopirin

Polopiryna

Premaspin

R16CO5Y76E [UNII]

Rheumin tabletten

Rheumintabletten

Rhodine

Rhonal

Ronal

S-211

SMR000059138

SP 189

SPBio_001838

SPECTRUM1500130

ST075414

Salacetin

Salcetogen

Saletin

Salicylic acid acetate

Salicylic acid, acetate

Salospir

Solfrin

Solprin

Solprin acid

Solpyron

Solupsan

Spectrum2_001899

Spectrum3_001295

Spectrum4_000099

Spectrum5_000740

Spectrum_001245

Spira-Dine

St. Joseph

St. Joseph Aspirin for Adults

Supac

Tasprin

Temperal

Toldex

Triaminicin

Triple-sal

UNII R16CO5Y76E

UNII-R16CO5Y76E

UNII=R16CO5Y76E

UNM-0000306102

Vanquish

WLN: QVR BOV1

XAXA

Xaxa

Yasta

ZORprin

acide 2-(acétyloxy)benzoïque

acide acétylsalicylique

aspirin

cMAP_000006

component of Midol

component of Synirin

nchem.859-comp6

o-Acetoxybenzoic acid

o-Carboxyphenyl acetate

o-acetoxybenzoic acid

o-carboxyphenyl acetate

salicylic acid acetate

ácido acetilsalicílico

Darunavir

approved

Phase 4

210

635728-49-3, 206361-99-1

213039

Synonyms:

(3-((4-aminobenzenesulfonyl)isobutylamino)-1-benzyl-2-hydroxypropyl)carbamic acid hexahydrofuro(2,3-b)furan-3-yl ester

(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE

(3R,3AS,6ar)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N(1)-isobutylsulfanilamido)propyl)carbamate

(3R,3AS,6ar)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate

(3R,3AS,6ar)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate

(3R,3AS,6ar)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-neopentylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate

(3R,3aS,6aR)-Hexahydrofuro(2,3-b)furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N1-isobutylsulfanilamido)propyl)carbamate

(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N(1)-isobutylsulfanilamido)propyl)carbamate

(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate

(3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate

(3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-neopentylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate

206361-99-1

2f80

2f81

2f8g

2hs1

2hs2

2idw

2ien

3bvb

3cyw

3d1z

3d20

618109-00-5

AC1L4U4V

AIDS073035

CHEBI:367163

CHEMBL1323

CID213039

Carbamic acid, [(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester

D03656

DB01264

Darunavir

Darunavir (USAN/INN)

Darunavir [USAN]

Darunavirum

Darunavirum [INN-Latin]

Darunavirum [INN-latin]

LS-187026

LS-187772

LS-191295

MolPort-003-846-141

N-((1S,2R)-3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6-dioxabicyclo(3.3.0)oct-2-yloxy)carboxamide

Prezista

Prezista(TM)

TMC 114

TMC-114

TMC114

UIC 94017

UIC-94017

UIC-96017

UNII-YO603Y8113

[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate

[(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-1-((R)-phenylmethyl)-propyl]-carbamic acid (3R,3aS,6aR)-(hexahydro-furo[2,3-b]furan-3-yl) ester

[(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-1-((R)-phenylmethyl)-propyl]-carbamic acid (3R,3as,6ar)-(hexahydro-furo[2,3-b]furan-3-yl) ester

{(1S,2R)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid (3R,3aS,6aR)-(hexahydro-furo[2,3-b]furan-3-yl) ester

{(1S,2R)-3-[(4-amino-benzenesulfonyl)-isobutyl-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid (3R,3as,6ar)-(hexahydro-furo[2,3-b]furan-3-yl) ester

Etravirine

approved

Phase 4

269055-15-4

193962

Synonyms:

269055-15-4

394729-17-0

4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-benzonitrile

4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE

4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile

65B

AC1L4XC5

CHEBI:213138

CHEMBL308954

CID193962

D04112

DAPY deriv

DB07191

Diaminopyrimidine deriv

Etravirine

Etravirine (JAN/USAN/INN)

I06-1887

Intelence

Intelence (TN)

Intelence(TM)

R 165335

R-165335

R165335

R165335-TMC125

ST51053273

TMC 125

TMC-125

TMC-125/R-165335

TMC125

UNII-0C50HW4FO1

ZINC00602632

Pyridoxine

approved, nutraceutical, vet_approved

Phase 4, Phase 3, Phase 2

188

65-23-6

1054

Synonyms:

(5-hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphate

12001-78-4

2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine

2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridine

2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin

2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin [German]

2-Methyl-3-hydroxy-4,5-dihydroxymethylpyridine

2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine

2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl) pyridine

2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine

2-methyl-4,5-dimethylol-pyridin-3-ol

2B3E07D2-E4CC-4CC5-B085-6070BA01F9F0

3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride

3-Hydroxy-2-Picoline-4,5-dimethanol

3-Hydroxy-4,5-dihydroxymethyl-2-methylpyridine hydrochloride

3-Hydroxy-4,5-dimethylol-.alpha.-picoline hydrochloride

3-Hydroxy-4,5-dimethylol-alpha-picoline

3-Hydroxy-4,5-dimethylol-alpha-picoline hydrochloride

3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine

4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol

4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride

4,5-bis(hydroxymethyl)-2-methyl-3-pyridinol hydrochloride

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol

4,5-bis(hydroxymethyl)-2-methylpyridine-3-ol

4-Deoxypyridoxine 5'-phosphate

47862_SUPELCO

5-Hydroxy-6-methyl-3,4-pyridinedicarbinol hydrochloride

5-Hydroxy-6-methyl-3,4-pyridinedimethanol

5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride

5-Hydroxy-6-methyl-3,4-pyridinedimethanol, hydrochloride

58-56-0

58-56-0 (HCL)

58-56-0 (hydrochloride)

65-23-6

65-23-6 (Parent)

8059-24-3

85078-23-5

AC-12024

AC-14512

AC-907/25014218

AC1L1AMH

AC1L1LMI

AC1L2XK2

AC1Q22HP

AC1Q2G66

AC1Q3F63

AI3-19016

AIDS-006784

AIDS006784

AR-1A6363

AR-1J1632

Adermin hydrochloride

Adermine

Adermine hydrochloride

Aderomine hydrochloride

Aderoxin

Aderoxine

Alestrol

BB_NC-0050

BIDD:PXR0180

BPBio1_000646

BSPBio_000586

Becilan

Beesix

Benadon

Bonasanit

C00314

C8H11NO3

CAS-58-56-0

CBDivE_015627

CCRIS 1903

CHEBI:16709

CHEBI:30961

CHEMBL1200756

CHEMBL1364

CID104817

CID1054

CID6019

CPD0-1221

Campoviton 6

Cernevit-12

D02179

D025101

D08454

DB00165

EINECS 200-386-2

EINECS 200-603-0

EINECS 232-503-8

Godabion

Gravidox

HMS1569N08

HMS2093L07

HSDB 1212

Hexa-Betalin

Hexa-Betalin (R)

Hexa-betalin (TN)

Hexabetalin

Hexabione hydrochloride

Hexavibex

Hexermin

Hexermine

Hexobion

Hydoxin

I02-1897

I02-2297

KST-1A8556

LS-134393

LS-187072

LS-2332

MLS001074329

MLS002153915

MolPort-002-137-856

MolPort-002-319-991

MolPort-005-933-330

NCGC00016261-01

NCGC00164317-01

NCGC00180946-01

NSC 36225

NSC36225

NSC36225 (HCL)

Nestrex

Oprea1_061614

P0561

P4722_SIAL

P5669_SIGMA

P6280_SIGMA

P8666_SIGMA

P9755_SIAL

PN HCl

PYRIDOXINE HYDROCHLORIDE

PYRIDOXINE HYDROCHLORIDE, U.S.P.

Paxadon

Piridossina

Piridossina [DCIT]

Piridoxina

Piridoxina [INN-Spanish]

Prestwick0_000623

Prestwick1_000623

Prestwick2_000623

Prestwick3_000623

Prestwick_925

Pydox

Pyridipca

Pyridox

Pyridoxin

Pyridoxin hydrochloride

Pyridoxine

Pyridoxine (INN)

Pyridoxine HCl

Pyridoxine Hydrochloride (B6)

Pyridoxine [INN:BAN]

Pyridoxine chloride

Pyridoxine hydrochloride (JP15/USP)

Pyridoxine hydrochloride [USAN:JAN]

Pyridoxine hydrogen chloride

Pyridoxine monohydrochloride

Pyridoxine, hydrochloride

Pyridoxine-HCl Microencapsulated

Pyridoxinium chloride

Pyridoxinum

Pyridoxinum [INN-Latin]

Pyridoxinum hydrochloricum

Pyridoxinum hydrochloricum (Hungarian)

Pyridoxol

Pyridoxol hydrochloride

Pyridoxol, hydrochloride

Pyridoxolum

Rodex

Rodex (R)

Rodex TD

SMP2_000230

SMR000674613

SPBio_002805

STK177324

STOCK1N-08684

Spondylonal

Tex Six T.R.

TimTec1_000657

UNII-68Y4CF58BV

UNII-KV2JZ1BI6Z

Vitamin B 6

Vitamin B6

Vitamin B6-hydrochloride

Vitamin V6

Vitamin V6 (TN)

Vitamin-?B6

Vitamin-?B6 hydrochloride

Vitaped

WLN: T6NJ B1 CQ D1Q E1Q &GH

ZINC00049154

ZINC21983293

bmse000288

c1302

component of Alestrol

nchembio.93-comp1

pyridoxine

vitamin B6

Pyridoxal

approved, nutraceutical

Phase 4, Phase 3, Phase 2

187

66-72-8

1050

Synonyms:

2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine

3-Hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde

3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde

3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde

3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde

Piridoxal

Pyridoxal

Pyridoxaldehyde

Immunosuppressive Agents

Phase 4, Phase 3, Phase 2

13086

Antiprotozoal Agents

Phase 4, Phase 3, Phase 2, Phase 1

2051

Antiparasitic Agents

Phase 4, Phase 3, Phase 2, Phase 1

2199

Benzonidazole

Phase 4, Phase 3, Phase 2

Anti-Infective Agents

Phase 4, Phase 3, Phase 2, Phase 1

22062

Adrenergic alpha-1 Receptor Antagonists

Phase 4

480

Adrenergic Agents

Phase 4, Phase 3

5352

Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination

Phase 4, Phase 3

Antimetabolites

Phase 4, Phase 3, Phase 2

12054

Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination

Phase 4, Phase 3

248

Reverse Transcriptase Inhibitors

Phase 4, Phase 3, Phase 2

1913

Lipid Regulating Agents

Phase 4, Phase 3, Phase 2

2766

Raltegravir Potassium

Phase 4, Phase 3, Phase 2

292

Cytochrome P-450 CYP2C9 Inhibitors

Phase 4, Phase 3, Phase 2

669

Peripheral Nervous System Agents

Phase 4, Phase 3

23689

Atazanavir Sulfate

Phase 4, Phase 3, Phase 2

223

Vitamin B 6

Phase 4, Phase 3, Phase 2

188

Integrase Inhibitors

Phase 4, Phase 3, Phase 2

418

HIV Integrase Inhibitors

Phase 4, Phase 3, Phase 2

397

Lamivudine, zidovudine drug combination

Phase 4, Phase 3

112

Hypolipidemic Agents

Phase 4, Phase 3, Phase 2

2785

HIV Protease Inhibitors

Phase 4, Phase 2, Phase 3

5470

Antibiotics, Antitubercular

Phase 4, Phase 2, Phase 3

7180

Anti-HIV Agents

Phase 4, Phase 2, Phase 3

3162

Anti-Retroviral Agents

Phase 4, Phase 2, Phase 3

3296

Natriuretic Peptide, Brain

Phase 4

182

Neurotransmitter Agents

Phase 4, Phase 3, Phase 2

18340

Anti-Bacterial Agents

Phase 4, Phase 2, Phase 3

11226

Anticoagulants

Phase 4

2623

Interventional clinical trials:

(show top 50) (show all 106)

id	Name	Status	NCT ID	Phase
1	Optimization of PCR Technique to Assess Parasitological Response for Patients With Chronic Chagas Disease	Unknown status	NCT01678599	Phase 4
2	Population Pharmacokinetics Study of Benznidazole in Children With Chagas'Disease	Unknown status	NCT01549236	Phase 4
3	Population Pharmacokinetics in Benznidazole-treated Adults With Chronic With Chagas Disease	Completed	NCT01755403	Phase 4
4	Exercise Training in Chagas Cardiomyopathy	Completed	NCT01006473	Phase 4
5	A Randomized Trial of Carvedilol in Chronic Chagas Cardiomyopathy	Completed	NCT01557140	Phase 4
6	Outcomes of an Anticoagulation Clinic in an University Hospital	Completed	NCT01006486	Phase 4
7	An Evaluation of the Pharmacological Interaction of Lopinavir/r and Rifampin	Completed	NCT00771498	Phase 4
8	Immediate Versus Deferred Start of Anti-HIV Therapy in HIV-Infected Adults Being Treated for Tuberculosis	Completed	NCT00108862	Phase 4
9	Pharmacokinetics of the Tablet Formulation of Lopinavir/r as Standard and Increased Dosage During Pregnancy	Completed	NCT00605098	Phase 4
10	HIV Treatment Reinitiation in Women Who Received Anti-HIV Drugs to Prevent Mother-to-Child Transmission of HIV	Completed	NCT00442962	Phase 4
11	REMEMBER: Reducing Early Mortality & Morbidity by Empiric Tuberculosis (TB) Treatment	Completed	NCT01380080	Phase 4
12	Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings	Completed	NCT00084136	Phase 4
13	Clinical Assessment, Neuroimaging and Immunomarkers in Chagas Disease Study (CLINICS)	Recruiting	NCT01650792	Phase 4
14	A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure	Active, not recruiting	NCT01641367	Phase 4
15	Reveal Chagas: Clinical Evidence of the Implantable Cardiac Monitor in Patients With Chagas Disease	Terminated	NCT01539161	Phase 4
16	Randomized Clinical Trial to Assess the Efficacy and Safety of Concomitant Use of Rifampicin and Efavirenz 600 X 800mg	Terminated	NCT00533390	Phase 4
17	BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' Disease	Unknown status	NCT00123916	Phase 3
18	Etiologic Treatment With Benznidazole in Adult Patients With Chronic Chagas Disease. A Randomized Clinical Trial	Completed	NCT02386358	Phase 3
19	Cardiac Rehabilitation in Chagas Heart Failure	Completed	NCT02516293	Phase 2, Phase 3
20	Chagas Cardiomyopathy Bisoprolol Intervention Study: Charity	Completed	NCT00323973	Phase 3
21	Amprenavir/Ritonavir or Saquinavir/Ritonavir in HIV-Infected Subjects Following Failure With Kaletra as Their Second Protease Inhibitor	Completed	NCT00038519	Phase 2, Phase 3
22	Preventing Sexual Transmission of HIV With Anti-HIV Drugs	Completed	NCT00074581	Phase 3
23	Quadrivalent HPV Vaccine to Prevent Anal HPV in HIV-infected Men and Women	Completed	NCT01461096	Phase 3
24	Study of Options for Second-Line Effective Combination Therapy (SELECT)	Completed	NCT01352715	Phase 3
25	A Study to Compare Two Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Previously Received Anti-HIV Treatment	Completed	NCT00004581	Phase 3
26	A Phase III Study Comparing Two Different Anti-HIV Drug Combinations in HIV-Positive Patients Without Previous Anti-HIV Drug Therapy	Completed	NCT00004583	Phase 3
27	Safety and Efficacy of COBI-boosted Atazanavir Versus Ritonavir-boosted Atazanavir Each Administered With Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults	Completed	NCT01108510	Phase 3
28	Rollover Trial Safety and Tolerability of Combination Tipranavir and Ritonavir Use in HIV 1 Infected Subjects	Completed	NCT00146328	Phase 2, Phase 3
29	Study of Immunogenicity, Reactogenicity and Safety of the Combined Measles, Mumps and Rubella Vaccine Produced by Bio-Manguinhos/Fiocruz in Children 12-15 Months of Age, Followed by Tetraviral Vaccine in Children 15-18 Months.	Completed	NCT01991899	Phase 3
30	Prospective Study of a Pediatric Nifurtimox Formulation for Chagas' Disease	Recruiting	NCT02625974	Phase 3
31	Selenium Treatment and Chagasic Cardiopathy (STCC)	Recruiting	NCT00875173	Phase 3
32	CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY)	Recruiting	NCT02369978	Phase 2, Phase 3
33	Low Antimonial Dosage in American Mucosal Leishmaniasis	Recruiting	NCT01301937	Phase 2, Phase 3
34	Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults	Recruiting	NCT02344290	Phase 3
35	TBTC Study 31: Rifapentine-containing Tuberculosis Treatment Shortening Regimens	Recruiting	NCT02410772	Phase 3
36	Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment	Recruiting	NCT02548351	Phase 3
37	Three Chemo Regimens as an Adjunct to ART for Treatment of Advanced AIDS-KS	Recruiting	NCT01435018	Phase 3
38	Physical Exercise Program in Chronic Chagas Heart Disease	Active, not recruiting	NCT02517632	Phase 3
39	Comparison of Standard and Alternative Antimonial Dosage in Patients With American Cutaneous Leishmaniasis	Active, not recruiting	NCT01301924	Phase 2, Phase 3
40	Evaluating the Safety and Effectiveness of Short-Course Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-Infected Individuals With Latent Tuberculosis Infection	Active, not recruiting	NCT01404312	Phase 3
41	Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcoma	Active, not recruiting	NCT01352117	Phase 3
42	Open-label Safety Study of E/C/F/TAF (Genvoya®) in HIV-1 Positive Patients With Mild to Moderate Renal Impairment	Active, not recruiting	NCT01818596	Phase 3
43	Can Valacyclovir Delay the Need for Initiation of Human Immunodeficiency Virus (HIV) Treatment in HIV-infected Individuals?	Active, not recruiting	NCT00860977	Phase 3
44	Switching From a TDF-Containing Combination Regimen to a TAF-Containing Fixed Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Positive Participants	Active, not recruiting	NCT01815736	Phase 3
45	Treatment of Asymptomatic Toxocariasis With Albendazole in Children	Active, not recruiting	NCT00755560	Phase 3
46	Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis	Terminated	NCT00330148	Phase 3
47	Cell Therapy in Chagas Cardiomyopathy	Terminated	NCT00349271	Phase 3
48	Proof-of-Concept Study of E1224 to Treat Adult Patients With Chagas Disease	Unknown status	NCT01489228	Phase 2
49	Safety of and Immunogenicity to an H1N1 Influenza Vaccine in HIV-infected Adults	Unknown status	NCT01155037	Phase 2
50	A Study of the Use of Oral Posaconazole (POS) in the Treatment of Asymptomatic Chronic Chagas Disease (P05267)	Completed	NCT01377480	Phase 2

Search NIH Clinical Center for Chagas Disease

Genetic Tests for Chagas Disease

Anatomical Context for Chagas Disease

Sources:
³⁶MalaCards
See all MalaCards sources

MalaCards organs/tissues related to Chagas Disease:

³⁶

Heart, Testes, Eye, Colon, Lymph node, T cells, Skin

Publications for Chagas Disease

Sources:
⁵⁷PubMed
See all MalaCards sources

Articles related to Chagas Disease:

(show top 50) (show all 806)

id	Title	Authors	Year
1	Triatoma vitticeps subcomplex (Hemiptera, Reduviidae, Triatominae): a new grouping of Chagas disease vectors from South America. (28407782)	Alevi K.C.... da Rosa J.A.	2017
2	Interdisciplinary approach at the primary healthcare level for Bolivian immigrants with Chagas disease in the city of SALo Paulo. (28333923)	Shikanai Yasuda M.A.... Carneiro N.	2017
3	Chagas disease in Europe: A review for the internist in the globalized world. (28502864)	Antinori S.... Corbellino M.	2017
4	Challenges in the management of Chagas disease in Latin-American migrants in Europe. (28428122)	Monge-Maillo B.... LA^pez-VAclez R.	2017
5	Molecular and serological detection of Trypanosoma cruzi in dogs (Canis lupus familiaris) suggests potential transmission risk in areas of recent acute Chagas disease outbreaks in Colombia. (28532988)	Jaimes-DueA+ez J.... GA^ngora-Orjuela A.	2017
6	Prevalence of Chagas Disease in a U.S. Population of Latin American Immigrants with Conduction Abnormalities on Electrocardiogram. (28056014)	Traina M.I.... Meymandi S.K.	2017
7	Chagas disease: national survey of seroprevalence in children under five years of age conducted in 2008. (28443980)	Russomando G.... Benitez L.	2017
8	Modeling Chagas disease in Chile: From vector to congenital transmission. (28435013)	Canals M.... Cattan P.E.	2017
9	Temporal Variation in the Abundance and Timing of Daily Activity of Chagas Disease Vector Triatoma gerstaeckeri (StAYl, 1859) in a Natural Habitat in the Lower Rio Grande Valley, South Texas. (28530845)	Flores A.... Fredensborg B.L.	2017
10	Ten years of Chagas disease research: Looking back to achievements, looking ahead to challenges. (28426735)	Dumonteil E.... Herrera C.	2017
11	Towards improving early diagnosis of congenital Chagas disease in an endemic setting. (28369287)	Messenger L.A.... Bern C.	2017
12	Chagas disease immunogenetics: elusive markers of disease progression. (28388241)	Ortega Zamora Y.... Gutierrez F.R.S.	2017
13	The process of lipid storage in insect oocytes: The involvement of I^-chain of ATP synthase in lipophorin-mediated lipid transfer in the chagas' disease vector Panstrongylus megistus (Hemiptera: Reduviidae). (27983943)	Fruttero L.L.... Canavoso L.E.	2017
14	Chagas disease research and development: Is there light at the end of the tunnel? (28066534)	Chatelain E.	2017
15	Participation of TLR2 and TLR4 in Cytokines Production by Patients with Symptomatic and Asymptomatic Chronic Chagas Disease. (27783847)	Mendes da Silva L.D.... Calvi S.A.	2017
16	Understanding transmissibility patterns of Chagas disease through complex vector-host networks. (28077180)	Rengifo-Correa L.... GonzA!lez-Salazar C.	2017
17	Autochthonous Chagas disease in the southern United States: A case report of suspected residential and military exposures. (28418113)	Harris N.... Garcia M.N.	2017
18	Access to Chagas disease treatment in non-endemic countries: the case of Spain. (28495262)	Navarro M.... de Los Santos J.J.	2017
19	Genetic Polymorphisms of IL17 and Chagas Disease in the South and Southeast of Brazil. (28470012)	Reis P.G.... Visentainer J.E.L.	2017
20	The Evolutionary Origin of Diversity in Chagas Disease Vectors. (27986547)	Justi S.A.... GalvALo C.	2017
21	Development of Diagnostics for Chagas Disease: Where Should We Put Our Limited Resources? (28056025)	Picado A.... Moriana S.	2017
22	The Prevalence of Trypanosoma cruzi, the Causal Agent of Chagas Disease, in Texas Rodent Populations. (28091763)	Aleman A.... Hahn D.	2017
23	Unraveling Chagas disease transmission through the oral route: Gateways to Trypanosoma cruzi infection and target tissues. (28379959)	Silva-Dos-Santos D.... Meis J.	2017
24	The Prevalence of Chagas Disease Among Latin American Immigrants with Pacemakers in Los Angeles, California. (28500812)	Park S.... Meymandi S.K.	2017
25	Automated identification of insect vectors of Chagas disease in Brazil and Mexico: the Virtual Vector Lab. (28439451)	Gurgel-GonAsalves R.... Ramsey J.M.	2017
26	Evaluation of P2X7 receptor expression in peripheral lymphocytes and immune profile from patients with indeterminate form of Chagas disease. (28062289)	Souza V.D.... Rosa Leal D.B.	2017
27	Leishmanicidal and Trypanocidal Activity of Metal Complexes with 1,2,4-Triazolo[1,5-a]pyrimidines: Insights on their Therapeutic Potential against Leishmaniasis and Chagas Disease. (28521698)	Salas J.M.... MAcndez-Arriaga J.M.	2017
28	Regarding Perspective Piece from July 2016 "What Do We Know About Chagas Disease in the United States? (28471741)	Nelson K.E.... Leiby D.A.	2017
29	Rapid diagnostic tests duo as alternative to conventional serological assays for conclusive Chagas disease diagnosis. (28369081)	EgA1ez K.E.... Pinazo M.J.	2017
30	The molecular sensory machinery of a Chagas disease vector: expression changes through imaginal moult and sexually dimorphic features. (28059141)	Latorre-Estivalis J.M.... Lorenzo M.G.	2017
31	Performance Assessment of Four Chimeric Trypanosoma cruzi Antigens Based on Antigen-Antibody Detection for Diagnosis of Chronic Chagas Disease. (27517281)	Santos F.L.... Krieger M.A.	2016
32	Advances and Progress in Chagas Disease Drug Discovery. (27072717)	Ferreira L.G.... Andricopulo A.D.	2016
33	Community resilience and Chagas disease in a rural region of Mexico. (27509012)	Rangel J.A.... Ramsey J.M.	2016
34	Serological Diagnosis of Chronic Chagas Disease: Is It Time for a Change? (27053668)	Abras A.... MuA+oz C.	2016
35	Orally-transmitted Chagas disease. (27993415)	Filigheddu M.T.... Ramos J.M.	2016
36	Acute colonic complications in a patient with Chagas disease. (27128343)	Lara Romero C.... Romero PAcrez E.	2016
37	Oesophageal motility disorders in infected immigrants with Chagas disease in a non-endemic European area. (27536373)	Roure S.... Serra J.	2016
38	IL18 Gene Variants Influence the Susceptibility to Chagas Disease. (27027876)	Leon Rodriguez D.A.... Martin J.	2016
39	Morphological and Genetic Differentiation within the Southernmost Vector of Chagas Disease: Triatoma patagonica (Hemiptera - Reduviidae). (28005972)	Nattero J.... Panzera F.	2016
40	PHARMACOKINETICS OF BENZNIDAZOLE IN CHAGAS DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS. (27550362)	Wiens M.O.... Krolewiecki A.	2016
41	Scrutinizing the Biomarkers for the Neglected Chagas Disease: How Remarkable! (27563302)	Pinho R.T.... Antas P.R.	2016
42	Trypanosoma cruzi Infection Prevalence and Bloodmeal Analysis in Triatomine Vectors of Chagas Disease From Rural Peridomestic Locations in Texas, 2013-2014. (27106934)	Gorchakov R.... Murray K.O.	2016
43	Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness. (27501246)	Khare S.... Supek F.	2016
44	New cases of Chagas disease in a rural area of Northeast Brazilian. (27192597)	EuzAcbio D.M.... Silva A.M.	2016
45	Chronic Heart Disease after Treatment of Oral Acute Chagas Disease. (27627643)	Antunes A.F.... Ferreira J.M.	2016
46	Benznidazole therapy for Chagas disease in asymptomatic Trypanosoma cruzi -seropositive former blood donors: evaluation of the efficacy of different treatment regimens. (28001218)	Antunes A.P.... Botelho A.C.	2016
47	Chagas' disease in Aboriginal and Creole communities from the Gran Chaco Region of Argentina: Seroprevalence and molecular parasitological characterization. (27057620)	Lucero R.H.... Schijman A.G.	2016
48	Flavonoids and Chagas' disease: the story so far! (27558676)	Nabavi S.F.... Nabavi S.M.	2016
49	Analysis of Regional Left Ventricular Strain in Patients with Chagas Disease and Normal Left Ventricular Systolic Function. (27086044)	Gomes V.A.... Saraiva R.M.	2016
50	A Deep Insight into the Sialome of Rhodnius neglectus, a Vector of Chagas Disease. (27129103)	Santiago P.B.... Santana J.M.	2016

Genes related to Chagas Disease

Sources:
¹³DISEASES, ²¹GeneCards, ⁵⁰Novoseek
See all MalaCards sources

Genes related to Chagas Disease:

(show all 23)

- Elite gene

- Cancer Census gene in COSMIC

id	Symbol	Description	Score	Implication	PubmedIds
1	TNF	Tumor Necrosis Factor	43.52	DISEASES inferred ¹³ GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
2	IL10	Interleukin 10	43.47	DISEASES inferred ¹³ GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
3	IFNG	Interferon Gamma	42.62	DISEASES inferred ¹³ GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
4	IL2	Interleukin 2	41.72	DISEASES inferred ¹³ GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
5	TLR2	Toll Like Receptor 2	41.72	DISEASES inferred ¹³ GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
6	CCL2	C-C Motif Chemokine Ligand 2	41.54	DISEASES inferred ¹³ GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
7	IL6	Interleukin 6	41.34	DISEASES inferred ¹³ GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
8	IL1B	Interleukin 1 Beta	40.97	DISEASES inferred ¹³ GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
9	TLR4	Toll Like Receptor 4	40.74	DISEASES inferred ¹³ GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
10	NOS2	Nitric Oxide Synthase 2	39.90	DISEASES inferred ¹³ GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
11	CYP51A1	Cytochrome P450 Family 51 Subfamily A Member 1	38.86	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders, Publications (show sections)	16321980, 20429511
12	TGFB1	Transforming Growth Factor Beta 1	36.69	GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
13	NPPB	Natriuretic Peptide B	36.58	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders, Publications (show sections)	15761636, 12241721, 17057935 more 20142028, 15710733, 15034825, 12892979, 16023747, 20090473, 12737906
14	CXCL8	C-X-C Motif Chemokine Ligand 8	36.43	GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
15	IL12B	Interleukin 12B	36.43	GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
16	SMAD2	SMAD Family Member 2	36.43	GeneCards inferred via : Disorders, Publications, Pathways & Interactions (show sections)
17	CCR5	C-C Motif Chemokine Receptor 5 (Gene/Pseudogene)	35.88	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders, Publications (show sections)	16299288, 11703822
18	CALR	Calreticulin	35.74	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders, Pathways & Interactions (show sections)	19108895, 15128045
19	ADRB1	Adrenoceptor Beta 1	35.59	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders, Publications (show sections)	19823676
20	TCFL5	Transcription Factor Like 5	26.99	GeneCards inferred via : Disorders, Publications, Proteins (show sections)
21	NTRK1	Neurotrophic Receptor Tyrosine Kinase 1	25.27	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders, Publications (show sections)	15447671, 18832578, 18410251 more 18005706
22	CD4	CD4 Molecule	18.97	Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders, Publications (show sections)	1427979
23	AMD1	Adenosylmethionine Decarboxylase 1	14.85	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Publications (show sections)	9677309

Variations for Chagas Disease

Expression for genes affiliated with Chagas Disease

Sources:
¹⁸Gene Expression Omnibus DataSets
See all MalaCards sources

Search GEO for disease gene expression data for Chagas Disease.

Pathways for genes affiliated with Chagas Disease

Sources:
³Cell Signaling Technology, ³⁴KEGG, ⁴²NCBI BioSystems Database, ⁵⁵PathCards, ⁵⁸QIAGEN, ⁵⁹R&D Systems, ⁶⁰Reactome, ⁶⁵Thomson Reuters, ⁶⁶Tocris Bioscience
See all MalaCards sources

Pathways related to Chagas Disease according to KEGG:

³⁴

id	Name	KEGG Source Accession
1	Chagas disease (American trypanosomiasis)	hsa05142

Pathways related to Chagas Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 92)

id	Super pathways	Score	Top Affiliating Genes
1	Downstream signaling in naive CD8+ T cells⁴² Show member pathways Ras signaling in the CD4+ TCR pathway⁴²	9.9	IFNG, IL2, TNF
2	OX40 Pathway⁵⁸	9.9	IFNG, IL10, IL2
3	Th2 Differentiation Pathway⁵⁹	9.9	IFNG, IL10, IL2
4	LDL Oxidation in Atherogenesis⁵⁸	9.9	CCL2, IL1B, TNF
5	Antifolate resistance³⁴	9.9	IL1B, IL6, TNF
6	Regulation of Telomerase⁴²	9.8	IFNG, IL2, TGFB1
7	IL12 signaling mediated by STAT4⁴²	9.8	IFNG, IL2, TGFB1
8	Type II interferon signaling (IFNG)⁴²	9.8	IFNG, IL1B, NOS2
9	Overview of nanoparticle effects⁴²	9.8	CXCL8, IL6, TNF
10	IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types⁵⁹	9.8	IL1B, IL6, TGFB1
11	Validated transcriptional targets of AP1 family members Fra1 and Fra2⁴²	9.8	CCL2, CXCL8, IL6
12	Photodynamic therapy-induced AP-1 survival signaling.⁴²	9.7	IFNG, IL2, IL6, TNF
13	Fluid shear stress and atherosclerosis³⁴	9.7	CCL2, IFNG, IL1B, TNF
14	IL1 and megakaryocytes in obesity⁴²	9.7	CCL2, IFNG, IL1B, TLR2
15	TNF signaling pathway³⁴	9.7	CCL2, IL1B, IL6, TNF
16	MAPK Pathway⁶⁶ Show member pathways Toll-like Receptor Pathway⁶⁶	9.6	IL1B, IL2, TLR2, TLR4
17	Calcineurin-regulated NFAT-dependent transcription in lymphocytes⁴² Show member pathways Calcium signaling in the CD4+ TCR pathway⁴²	9.6	CXCL8, IFNG, IL2, TNF
18	Osteoclast differentiation³⁴	9.6	IFNG, IL1B, TGFB1, TNF
19	HIF-1 signaling pathway³⁴	9.6	IFNG, IL6, NOS2, TLR4
20	Glucocorticoid receptor regulatory network⁴²	9.6	CXCL8, IFNG, IL2, IL6
21	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers⁵⁹	9.6	IFNG, IL10, IL2, IL6, TNF
22	NF-kappa B signaling pathway³⁴	9.6	CXCL8, IL1B, TLR4, TNF
23	Innate Lymphoid Cell Differentiation Pathways⁵⁹	9.6	IFNG, IL10, IL1B, IL2, TNF
24	ATF-2 transcription factor network⁴²	9.5	CXCL8, IFNG, IL6, NOS2
25	TGF-beta Receptor Signaling (WikiPathways)⁴² Show member pathways TGF-beta Receptor Signaling⁴²	9.5	IFNG, SMAD2, TGFB1, TNF
26	TGF-beta signaling pathway (KEGG)³⁴ Show member pathways TGF-beta signaling pathway³⁴	9.5	IFNG, SMAD2, TGFB1, TNF
27	IL-15 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types⁵⁹ Show member pathways IL-2 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types⁵⁹	9.5	IFNG, IL10, IL2, TGFB1, TNF
28	Corticotropin-releasing hormone signaling pathway⁴²	9.5	CXCL8, IL2, TGFB1, TLR4
29	FoxO signaling pathway³⁴ Show member pathways Polo-like kinase signaling events in the cell cycle⁴² PLK2 and PLK4 events⁴²	9.5	IL10, IL6, SMAD2, TGFB1
30	IL-10 Pathway⁵⁸	9.5	IL10, IL1B, IL6, TLR4, TNF
31	Hepatitis C and Hepatocellular Carcinoma⁴²	9.5	CXCL8, IL6, NOS2, TGFB1
32	Immune response NFAT in immune response⁶⁵ Show member pathways Immune response T cell receptor signaling pathway⁶⁵ Immune response CD28 signaling⁶⁵ Immune response ICOS pathway in T-helper cell⁶⁵	9.4	IFNG, IL10, IL12B, IL2, TNF
33	Jak/STAT Signaling Pathway⁵⁹	9.4	IFNG, IL10, IL12B, IL2, IL6
34	Jak-STAT signaling pathway (KEGG)³⁴ Show member pathways Jak-STAT signaling pathway³⁴ Interleukin-19, 20, 22, 24⁶⁰ IL-7 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types⁵⁹ B-Cell Development⁵⁸	9.4	IFNG, IL10, IL12B, IL2, IL6
35	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways⁴²	9.4	CXCL8, IL10, IL1B, IL6, TNF
36	Development and heterogeneity of the ILC family⁴²	9.4	IFNG, IL12B, IL1B, IL6, TNF
37	Dilated cardiomyopathy³⁴ Show member pathways Hypertrophic cardiomyopathy (HCM)³⁴	9.4	ADRB1, IL6, TGFB1, TNF
38	Diseases associated with the TLR signaling cascade⁶⁰ Show member pathways Diseases of Immune System⁶⁰ MyD88 deficiency (TLR2/4)⁶⁰ TLR4 Signaling and Tolerance⁴² Toll-like Receptor Signaling⁴² IRAK4 deficiency (TLR2/4)⁶⁰ Simplified Depiction of MYD88 Distinct Input-Output Pathway⁴² MyD88 deficiency (TLR5)⁶⁰ IRAK4 deficiency (TLR5)⁶⁰ Interleukin-1 Induced Activation of NF-kappa-B⁴² IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation⁶⁰ IRAK1 recruits IKK complex⁶⁰	9.4	CXCL8, IL6, TLR2, TLR4, TNF
39	TRAF Pathway⁵⁸ Show member pathways Toll-Like Receptors Pathway⁵⁸ TNF Superfamily Pathway⁵⁸ 14-3-3 Induced Apoptosis⁵⁸	9.3	IL12B, IL1B, TLR2, TLR4, TNF
40	Folate Metabolism⁴² Show member pathways Vitamin B12 Metabolism⁴² Selenium Micronutrient Network⁴² thioredoxin pathway⁴²	9.3	CCL2, IFNG, IL1B, IL2, IL6, TNF
41	Senescence and Autophagy in Cancer⁴²	9.3	CXCL8, IFNG, IL1B, IL6, TGFB1
42	Transcription_Role of VDR in regulation of genes involved in osteoporosis⁶⁵	9.3	CALR, IFNG, IL1B, IL6, TNF
43	African trypanosomiasis³⁴	9.2	IFNG, IL10, IL12B, IL1B, IL6, TNF
44	NF-kappaB Signaling³	9.2	CCL2, IFNG, IL10, IL1B, IL2, TLR2
45	Aryl Hydrocarbon Receptor Pathway⁴²	9.1	IFNG, IL12B, IL1B, IL2, TGFB1, TNF
46	Pathways in cancer³⁴	9.1	CXCL8, IL6, NOS2, SMAD2, TGFB1
47	Salmonella infection (KEGG)³⁴ Show member pathways Salmonella infection³⁴	9.1	CXCL8, IFNG, IL1B, IL6, NOS2, TLR4
48	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways⁶⁰ Show member pathways TRAF3-dependent IRF activation pathway⁶⁰ TRAF6 mediated IRF7 activation⁶⁰ Cytosolic DNA-sensing pathway³⁴ RIG-I-like Receptor Signaling⁴² Virus Detection and Induction of Antiviral Signaling Pathways by RIG-I-like Receptors (RLR)⁵⁹ RIG-I-like receptor signaling pathway³⁴ NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10⁶⁰ Negative regulators of RIG-I/MDA5 signaling⁶⁰	9.1	CXCL8, IFNG, IL12B, IL1B, IL6, TNF
49	Dendritic Cells Developmental Lineage Pathway⁵⁹	9.1	IFNG, IL10, IL1B, IL2, IL6, TGFB1
50	IL-17 Family Signaling Pathways⁵⁹ Show member pathways IL-17 signaling pathway³⁴ Mucin expression in CF via IL-6, IL-17 signaling pathways⁶⁵ IL17 signaling pathway⁴² Interleukin-17 signaling⁶⁰	9.0	CCL2, CXCL8, IFNG, IL1B, IL6, TLR2

GO Terms for genes affiliated with Chagas Disease

Sources:
¹⁹Gene Ontology
See all MalaCards sources

Cellular components related to Chagas Disease according to GeneCards Suite gene sharing:

id	Name	GO ID	Score	Top Affiliating Genes
1	external side of plasma membrane	GO:0009897	9.7	CALR, CCR5, IFNG, IL6, TLR4, TNF
2	cell surface	GO:0009986	9.6	CALR, CCR5, TGFB1, TLR2, TLR4, TNF
3	extracellular region	GO:0005576	8.3	CALR, CCL2, CXCL8, IFNG, IL10, IL12B
4	extracellular space	GO:0005615	7.6	CALR, CCL2, CXCL8, IFNG, IL10, IL12B

Biological processes related to Chagas Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 108)

id	Name	GO ID	Score	Top Affiliating Genes
1	endothelial cell apoptotic process	GO:0072577	10.9	IL10, TNF
2	negative regulation of cytokine secretion involved in immune response	GO:0002740	10.9	IL10, TNF
3	epithelial cell proliferation involved in salivary gland morphogenesis	GO:0060664	10.9	IL6, TNF
4	positive regulation of isotype switching to IgG isotypes	GO:0048304	10.9	IFNG, IL2
5	negative regulation of lipid storage	GO:0010888	10.9	IL6, TNF
6	neutrophil apoptotic process	GO:0001781	10.9	IFNG, IL6
7	positive regulation of fever generation	GO:0031622	10.9	IL1B, TNF
8	cellular response to lipoteichoic acid	GO:0071223	10.9	TLR2, TLR4
9	positive regulation of interleukin-8 biosynthetic process	GO:0045416	10.9	TLR4, TNF
10	receptor biosynthetic process	GO:0032800	10.9	IL10, TNF
11	positive regulation of interleukin-6 biosynthetic process	GO:0045410	10.9	IFNG, IL1B
12	positive regulation of vitamin D biosynthetic process	GO:0060557	10.9	IFNG, TNF
13	positive regulation of interleukin-12 biosynthetic process	GO:0045084	10.8	IFNG, TLR4
14	positive regulation of killing of cells of other organism	GO:0051712	10.8	IFNG, NOS2
15	positive regulation of mononuclear cell migration	GO:0071677	10.8	TGFB1, TNF
16	positive regulation of leukocyte mediated cytotoxicity	GO:0001912	10.8	CCL2, NOS2
17	regulation of establishment of endothelial barrier	GO:1903140	10.8	IL1B, TNF
18	positive regulation of regulatory T cell differentiation	GO:0045591	10.8	IL2, TGFB1
19	regulation of defense response to virus by host	GO:0050691	10.8	IFNG, IL1B
20	regulation of vascular endothelial growth factor production	GO:0010574	10.8	CCL2, IL6
21	positive regulation of smooth muscle cell apoptotic process	GO:0034393	10.7	IFNG, IL12B
22	positive regulation of tissue remodeling	GO:0034105	10.7	IL12B, IL2
23	positive regulation of granulocyte macrophage colony-stimulating factor production	GO:0032725	10.7	IL12B, IL1B
24	defense response to Gram-positive bacterium	GO:0050830	10.7	IL6, TLR2, TNF
25	cellular response to estradiol stimulus	GO:0071392	10.7	CCL2, IL10, IL6
26	positive regulation of lymphocyte proliferation	GO:0050671	10.7	IL12B, TLR4
27	positive regulation of calcidiol 1-monooxygenase activity	GO:0060559	10.7	IFNG, IL1B, TNF
28	positive regulation of heterotypic cell-cell adhesion	GO:0034116	10.7	IL10, IL1B, TNF
29	positive regulation of chemokine biosynthetic process	GO:0045080	10.7	IFNG, IL1B, TNF
30	negative regulation of interleukin-6 production	GO:0032715	10.7	IL10, TLR4, TNF
31	positive regulation of membrane protein ectodomain proteolysis	GO:0051044	10.7	IFNG, IL1B, TNF
32	common-partner SMAD protein phosphorylation	GO:0007182	10.7	SMAD2, TGFB1
33	positive regulation of MHC class II biosynthetic process	GO:0045348	10.7	IFNG, IL10, TLR4
34	extrinsic apoptotic signaling pathway	GO:0097191	10.7	IFNG, TGFB1, TNF
35	negative regulation of mitotic cell cycle	GO:0045930	10.7	IL10, TGFB1, TNF
36	positive regulation of JNK cascade	GO:0046330	10.6	IL1B, TLR4, TNF
37	positive regulation of protein complex assembly	GO:0031334	10.6	IFNG, TGFB1, TNF
38	cellular response to drug	GO:0035690	10.6	CCL2, IL1B, NOS2
39	positive regulation of nitric-oxide synthase biosynthetic process	GO:0051770	10.6	CCL2, TLR2, TLR4
40	negative regulation of fat cell differentiation	GO:0045599	10.6	IL6, TGFB1, TNF
41	cellular response to dexamethasone stimulus	GO:0071549	10.6	CCL2, IL6, TGFB1
42	positive regulation of peptidyl-serine phosphorylation	GO:0033138	10.6	IL6, TGFB1, TNF
43	protein import into nucleus, translocation	GO:0000060	10.6	IFNG, TGFB1, TNF
44	regulation of binding	GO:0051098	10.6	SMAD2, TGFB1
45	positive regulation of osteoclast differentiation	GO:0045672	10.6	IFNG, IL12B, TNF
46	cellular response to interleukin-1	GO:0071347	10.6	CCL2, CXCL8, IL6
47	cellular response to mechanical stimulus	GO:0071260	10.6	IL1B, TGFB1, TLR4
48	response to insulin	GO:0032868	10.5	IL10, IL6, TLR2
49	cellular response to interferon-gamma	GO:0071346	10.5	CCL2, IL12B, NOS2
50	humoral immune response	GO:0006959	10.5	CCL2, IFNG, IL6, TNF

Molecular functions related to Chagas Disease according to GeneCards Suite gene sharing:

id	Name	GO ID	Score	Top Affiliating Genes
1	lipopolysaccharide receptor activity	GO:0001875	10.3	TLR2, TLR4
2	type I transforming growth factor beta receptor binding	GO:0034713	9.9	SMAD2, TGFB1
3	growth factor activity	GO:0008083	9.6	IL10, IL12B, IL2, IL6, TGFB1
4	cytokine activity	GO:0005125	8.8	CCL2, CXCL8, IFNG, IL10, IL12B, IL1B