Chagas Disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

MCID: CHG001 MIFTS: 67	Chagas Disease malady Categories: Rare diseases, Infectious diseases, Neuronal diseases
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Aliases & Classifications for Chagas Disease

Sources:
¹⁰Disease Ontology, ⁴⁵NIH Rare Diseases, ⁴⁷Novoseek, ¹²DISEASES, ⁵¹Orphanet, ³⁵MedlinePlus, ²CDC, ⁶⁵UMLS, ²⁹ICD9CM, ⁵⁹SNOMED-CT, ²⁸ICD10 via Orphanet, ⁶⁶UMLS via Orphanet, ²⁷ICD10
See all MalaCards sources

Aliases & Descriptions for Chagas Disease:

Name: Chagas Disease ¹⁰ ⁴⁵ ⁴⁷ ¹² ⁵¹ ³⁵ ² ⁶⁵

American Trypanosomiasis ¹⁰ ⁴⁵ ⁵¹ ²

Chagas' Disease with Digestive System Involvement ¹⁰

Chagas' Disease with Nervous System Involvement ¹⁰

Chagas' Disease with Other Organ Involvement ¹⁰

South American Trypanosomiasis ⁴⁵

New World Trypanosomiasis ⁴⁵

Chagas' Disease ¹⁰

Characteristics:

Orphanet epidemiological data:

⁵¹

chagas disease:
Inheritance: Not applicable; Prevalence: 6-9/10000 (United States); Age of onset: Adult

Classifications:

MalaCards categories:
Global: Rare diseases, Infectious diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

ICD10: ²⁸ ²⁷

Certain infectious and parasitic diseases

Protozoal diseases

Chagas disease

Chagas disease (chronic) with heart involvement

Chagas disease (chronic) with digestive system involvement

Chagas disease (chronic) with nervous system involvement

Chagas disease (chronic) with other organ involvement

Orphanet: ⁵¹

Rare infectious diseases

External Ids:

Disease Ontology¹⁰ DOID:12140

ICD9CM²⁹ 086.2

Orphanet⁵¹ 3386

SNOMED-CT⁵⁹ 186817003, 54570006, 94371000119107

ICD10 via Orphanet²⁸ B57.0, B57.1, B57.2 B57.3, B57.4, B57.5, more

UMLS via Orphanet⁶⁶ C0041234

ICD10²⁷ B57, B57.2 B57.3, B57.4, B57.5, more

UMLS⁶⁵ C0007932, C0041234

Summaries for Chagas Disease

Sources:
¹⁰Disease Ontology, ⁴⁵NIH Rare Diseases, ³⁵MedlinePlus, ²CDC, ⁶⁸Wikipedia, ³³MalaCards
See all MalaCards sources

MedlinePlus:³⁵ Chagas disease is caused by a parasite. it is common in latin america but not in the united states. infected blood-sucking bugs, sometimes called kissing bugs, spread it. when the bug bites you, usually on your face, it leaves behind infected waste. you can get the infection if you rub it in your eyes or nose, the bite wound or a cut. the disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. if you notice symptoms, they might include fever flu-like symptoms a rash a swollen eyelid these early symptoms usually go away. however, if you don't treat the infection, it stays in your body. later, it can cause serious intestinal and heart problems. a physical exam and blood tests can diagnose it. you may also need tests to see whether the disease has affected your intestines and heart. medicines can kill the parasite, especially early on. you can also treat related problems. for example, a pacemaker helps with certain heart complications. there are no vaccines or medicines to prevent chagas disease. if you travel to areas where it occurs, you are at higher risk if you sleep outdoors or in poor housing conditions. it is important to use insecticides to prevent bites, and practice food safety. centers for disease control and prevention

MalaCards based summary: Chagas Disease, also known as american trypanosomiasis, is related to trypanosomiasis and achalasia, and has symptoms including pruritus An important gene associated with Chagas Disease is TNF (Tumor Necrosis Factor), and among its related pathways are OX40 Pathway and LDL Oxidation in Atherogenesis. Affiliated tissues include heart, testes and eye, and related mouse phenotypes are adipose tissue and craniofacial.

Disease Ontology:¹⁰ A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.

NIH Rare Diseases:⁴⁵ Chagas disease is caused by the parasite, trypanosoma cruzi. when a triatomine bug (commonly known as a "kissing bug") infected with this parasite bites you, usually on your face, it leaves behind infected waste which can be spread into your eyes, nose, or a wound. chagas disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. symptoms can include fever, flu-like symptoms, a rash or swollen eyelid. early symptoms usually go away but if not treated, the infection can later cause serious intestinal and heart problems. chagas disease is common in latin america but not in the united states. last updated: 3/4/2014

CDC:² Chagas disease is named after the Brazilian physician Carlos Chagas, who discovered the disease in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors and is found only in the Americas (mainly, in rural areas of Latin America where poverty is widespread). Chagas disease (T. cruzi infection) is also referred to as American trypanosomiasis.

Wikipedia:⁶⁸ Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by the... more...

Related Diseases for Chagas Disease

Sources:
²⁰GeneCards, ¹⁹GeneAnalytics
See all MalaCards sources

Diseases related to Chagas Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 301)

id	Related Disease	Score	Top Affiliating Genes
1	trypanosomiasis	32.2	IL10, IL6, NOS2
2	achalasia	30.7	CD4, IL10, TNF
3	systemic lupus erythematosus	29.7	CCL2, IFNG, IL10, IL2, IL6, TNF
4	hiv-1	28.8	CCL2, CCR5, CD4, IFNG, IL10, TNF
5	obesity	28.5	ADRB1, CCL2, IL10, IL1B, IL6, TGFB1
6	malaria	27.5	CCL2, GSR, IFNG, IL10, IL12B, IL1B
7	punctate palmoplantar keratoderma type 2	10.9	IL10, TNF
8	polycythemia	10.9	IL1B, TNF
9	primary progressive freezing gait	10.9	IL10, TNF
10	ureterocele	10.8	IL2, TNF
11	cycloplegia	10.8	IFNG, IL10
12	hypercementosis	10.8	IFNG, IL10, TNF
13	hydronephrosis	10.8	IFNG, IL10, TNF
14	gonococcal bursitis	10.8	CCL2, IFNG, TNF
15	central nervous system melanocytic neoplasm	10.8	IFNG, IL10, TNF
16	stargardt macular degeneration absent or hypoplastic corpus callosum mental retardation and dysmorphic features	10.8	IL1B, TNF
17	autoimmune oophoritis	10.8	IFNG, TNF
18	blastomycosis	10.8	IFNG, IL10, TNF
19	graft-versus-host disease, protection against	10.8	IFNG, IL10, IL2
20	lymph node cancer	10.8	TLR2, TLR4
21	anti-hla hyperimmunization	10.8	TLR2, TLR4, TNF
22	angioid streaks of choroid	10.7	IFNG, TLR2, TLR4
23	argentine hemorrhagic fever	10.7	IFNG, IL2, TNF
24	precursor b lymphoblastic lymphoma/leukemia	10.7	IL10, IL6, TNF
25	protein r deficiency	10.7	IL1B, TLR2, TLR4
26	ileocolitis	10.7	TLR2, TLR4, TNF
27	goat milk allergy	10.7	IL10, TGFB1, TNF
28	photokeratitis	10.7	IFNG, IL1B, TLR4
29	primary progressive multiple sclerosis	10.7	CCL2, IFNG, IL10
30	plantar nerve lesion	10.7	IL1B, IL6, TNF
31	spinal polio	10.7	IFNG, IL2, TLR4
32	lujo hemorrhagic fever	10.7	IL1B, IL6, TNF
33	interstitial emphysema	10.7	IFNG, TLR2, TLR4
34	noonan-like/multiple giant cell lesion syndrome	10.7	IL12B, TLR2, TNF
35	common cold	10.7	TLR2, TLR4, TNF
36	pediatric infratentorial ependymoma	10.7	IL10, IL1B, TNF
37	residual stage angle-closure glaucoma	10.7	IL1B, IL6, TNF
38	keshan disease	10.7	IFNG, TLR2, TLR4
39	neonatal period electroclinical syndrome	10.7	IL10, IL1B, IL6
40	congenital dyserythropoietic anemia	10.7	CCL2, IFNG, IL6
41	thrombocytopenia due to platelet alloimmunization	10.7	IL2, TLR2, TNF
42	sarcoidosis, early-onset	10.7	IL1B, TLR4, TNF
43	refractory plasma cell neoplasm	10.7	IL1B, IL6, TNF
44	skin conditions	10.7	IL1B, IL6, TNF
45	peyronie's disease	10.7	IL1B, TNF
46	postsurgical hypothyroidism	10.7	IL1B, IL6, TNF
47	intermediate dend syndrome	10.7	IL6, TNF
48	ureteral disease	10.7	IL1B, IL6, TNF
49	miliary tuberculosis	10.7	IFNG, IL2, TNF
50	blackwater fever	10.7	IFNG, IL10, TNF

Graphical network of the top 20 diseases related to Chagas Disease:

Symptoms for Chagas Disease

Sources:
⁶⁵UMLS
See all MalaCards sources

UMLS symptoms related to Chagas Disease:

pruritus

Drugs & Therapeutics for Chagas Disease

Sources:
⁴⁴NIH Clinical Center, ⁴ClinicalTrials, ⁶⁵UMLS, ⁴³NDF-RT, ¹³DrugBank, ²⁶HMDB, ⁹DGIdb, ⁵³PharmGKB, ³⁰IUPHAR, ⁴⁷Novoseek, ¹BitterDB
See all MalaCards sources

Drugs for Chagas Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 155)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Efavirenz

approved, investigational

Phase 4, Phase 3, Phase 2

398

154598-52-4

64139

Synonyms:

(-)-6-CHLORO-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one

(-)-Efavirenz

(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

(4S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one

(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one

(4S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one

(S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-ben

(S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

(S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one

(S)-6-chloro-4-(Cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

(S)-6-chloro-4-Cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[D][1,3]oxazin-2-one

154598-52-4

1ikv

1ikw

2H-3,1-Benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)- (9

6-chloro-4-(2-Cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[D][1,3]oxazin-2-one

6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one

AC-19049

AC1L20IX

BIDD:GT0383

C08088

C14H9ClF3NO2

CHEBI:119486

CHEMBL223228

CID64139

CPD000466351

D00896

DB00625

DB07709

DMP 266

DMP-266

EFV

EFZ

Efavirenz

Efavirenz (JAN/INN)

Efavirenzum

Eravirenz

HMS2051J08

HMS2090N16

HSDB 7163

L 743726

L-741211

L-743,726

L-743725

L-743726

LS-173464

MLS000759465

MLS001424087

Met-SDF-1.beta. & Efavirenz

Met-Stromal Cell-derived Factor-1.beta. (Human) & Efavirenz

MolPort-003-983-924

NSC742403

SAM001246667

SBB066062

SMR000466351

Stocrin

Strocin (TM)

Sustiva

Sustiva (TM)

Sustiva (TN)

UNII-JE6H2O27P8

ZINC02020233

efavirenz

efavirenz, (S)-isomer

zoxazin-2-one

Éfavirenz

Didanosine

approved

Phase 4, Phase 3

150

69655-05-6

50599

Synonyms:

149409-57-4

2',3'-Dideoxyinosine

2',3'-Dideoxyinosine & Granulocyte-macrophage colony-stimulating factor

2',3'-Dideoxyinosine & Interferon-.alpha.

2',3'-Dideoxyinosine & sCD4(soluble recombinant protein)

2',3'-Dideoxyinosine (AIDS Initiative)

2',3'-Dideoxyinosine (ddI)

2',3'-dideoxyinosine, DDI, NSC 612049, Didanosine

2'3'-DIDEOXYINOSINE

2,3-Dideoxyinosine

2,3-dideoxyinosine

2DI

3'-Azido-3'-deoxythymidine + 2',3'-Dideoxyinosine

69655-05-6

9-((2R,5S)-5-(Hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one

9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one

9-((2R,5S)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one

9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ol

9-(2,3-Dideoxy-beta-D-ribofuranosyl)-6-oxopurine

9-(2,3-Dideoxy-beta-D-ribofuranosyl)hypoxanthine

9-[(2R,5R)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL]-1,9-DIHYDRO-6H-PURIN-6-ONE

9-[(2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one

9-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one

9-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one

AC-12026

AC1L19ET

AC1L3OPK

BMY 40900

BMY-40900

BRN 3619529

Benzeneethanamine, 4-methoxy-3-(2-phenylethoxy)-N,N-dipropyl-, hydrochloride

Bio-0685

C06953

C083832

CCRIS 805

CHEBI:490877

CHEMBL1460

CID119381

CID50599

CPD000058576

D00296

D2I

D3066

DB00900

DB02392

DDI

DDI and rIFN.alpha.2

DIDEOXYINOSINE

DRG-0016

DS-4152 & ddI

DdIno

Didanosina

Didanosina [INN-Spanish]

Didanosine

Didanosine (JAN/USAN/INN)

Didanosine and Interferon-.alpha.-2

Didanosinum

Didanosinum [INN-Latin]

Dideoxyinosine

Dideoxyinosine (DDI)

FT-0082664

HMS2051J11

HMS2089N20

HSDB 6548

Hypoxanthine ddN

Inosine, 2',3'-dideoxy- & Recombinant Interferon-.alpha.-2

Intron A & Videx

KS-1049

LOA & ddI

Listera ovata agglutinin & 2',3'-Dideoxyinosine

MLS000759469

MLS001055350

MLS001424118

MLS002154216

MolPort-002-507-371

MolPort-002-885-819

N,N-Dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride

N,N-diethyl-2-(4-methoxy-3-phenethyloxyphenyl)ethanamine hydrochloride

NCGC00090691-01

NCGC00159514-02

NCGC00159514-03

NCGC00164280-01

NE 100

NE-100

NSC 612049

NSC-612049

NSC612049

PC-SOD+ddI

S1702_Selleck

SAM001246673

SMR000058576

Sulfated polysaccharide-peptidoglycan DS-4152 & 2',3'-Dideoxyinosine

UNII-K3GDH6OH08

Videx

Videx (TN)

Videx EC

Videx EC(TM)(slow-release capsules)

Videx Ec

Videx(TM)

ZINC13597823

ddI & GM-CSF

ddI & IFN-.alpha.

ddI & sCD4(rsCD4)

ddI + d4T combination

ddIno

didanosine

Lamivudine

approved, investigational

Phase 4, Phase 3, Phase 2

594

134678-17-4

60825

Synonyms:

(+/-) (Cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

(+/-)-3TC

(+/-)-BCH-189

(+/-)-SddC

(-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine

(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine

(-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

(-)-2'-Deoxy-3'-thiacytidine

(-)-BCH 189

(-)-BCH-189

(-)-SddC

(-)-beta-L-2',3'-Dideoxy-3'-thiacytidine

(-)NGPB-21

(2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one

.beta.-L-(-)-2',3'-dideoxy-3'-thiacytidine & Sho-Saiko-To

134678-17-4

2',3' Dideoxy 3' thiacytidine

2',3'-Dideoxy-3'-thiacytidine

2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (+/-) (Cis)

2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S)

2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Galanthus Nivalis Agglutinin (GNA)

2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Hippeastrum hybrid agglutinin( HHA)

3'-Thia-2',3'-dideoxycytidine

3-TC

3TC

3TC & GNA

3TC & SST

3TC (AIDS INITIATIVE) (AIDS INITIATIVE)

3TC and NV-01

3TC, Zeffix, Heptovir, Epivir, Epivir-HBV, Lamivudine

4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone

4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one

4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

480434-79-5

AC-1416

AC1L1TZZ

AC1Q6C34

BCH 189

BCH-189

BCH-790

BCH189

BIDD:GT0033

Bio-0652

C07065

C8H11N3O3S

CCRIS 9274

CHEBI:133986

CHEMBL141

CID60825

CPD000466319

D00353

D019259

DB00709

DRG-0126

DTHC

Epivir

Epivir (TN)

Epivir HBV

Epivir(TM)

Epivir-HBV

Epzicom

FT-0082667

GG-714

GR 109714 X

GR 109714X

GR-109714X

GR109714X

HHA & 3TC

HHA & Lamivudine

HMS2051D21

HSDB 7155

Hepitec

Heptivir

Heptodin

Heptovir

L0217

LMV

LS-2107

Lamivir

Lamivudin

Lamivudina

Lamivudine

Lamivudine & GNA

Lamivudine (JAN/USP/INN)

Lamivudine [USAN:BAN:INN]

Lamivudine [USAN:INN:BAN]

Lamivudine [Usan:Ban:Inn]

Lamivudine, (2S-cis)-Isomer

Lamivudinum

MLS000759424

MLS001424097

MolPort-002-507-347

NCGC00159341-03

NCGC00159341-04

NSC620753

S1706_Selleck

SAM001246582

SAM002589994

SMR000466319

STK801940

UNII-2T8Q726O95

ZINC00012346

Zeffix

Zefix

beta-L-2',3'-Dideoxy-3'-thiacytidine

beta-L-3'-Thia-2',3'-dideoxycytidine

lamivudine

Carvedilol

approved, investigational

Phase 4

153

72956-09-3

2585

Synonyms:

(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol

(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol

(+-)-1-Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol

(+/-)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol

1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol

1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol

1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol

1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol

107741-96-8

72956-09-3

AB1004830

AC-1641

AC1L1E0B

Artist

Artist (TN)

Atlana Pharma brand of carvedilol

BM 14190

BM-14-190

BM-14.190

BM-14190

BRD-A10977446-001-04-8

BRD-A10977446-045-01-1

Bio-0014

C043211

C06875

C2260

C24H26N2O4

CHEBI:3441

CHEMBL723

CID2585

CPD000449280

Carvedilol

Carvedilol (JAN/USAN/INN)

Carvedilol [USAN:INN:BAN:JAN]

Carvedilolum

Carvedilolum [Latin]

Coreg

Coreg (TN)

Coreg CR

Coropres

Coropress

D00255

DB01136

DQ 2466

DQ-2466

Dibloc

Dilatrend

EG-P042

Eucardic

GlaxoSmithKline brand of carvedilol

HMS2051N03

HMS2089B09

HMS2093E12

HSDB 7044

I06-0064

I06-1477

KBio2_002145

KBio2_004713

KBio2_007281

KBio3_002323

KBioGR_001252

KBioSS_002145

Kredex

L001243

LS-121875

Lakeside brand of carvedilol

MLS000758299

MLS000759508

MLS001424092

MolPort-003-666-814

NCGC00167832-01

NCGC00167832-02

NCGC00167832-03

Querto

Roche brand of carvedilol

SAM001246736

SAM001247021

SK&F-105517

SKF 105517

SMR000449280

SPBio_001885

STK621453

Spectrum2_001673

Spectrum3_001182

Spectrum4_000636

Spectrum5_001436

Spectrum_001665

TL8005080

UNII-0K47UL67F2

carvedilol

carvedilol, (+-)-isomer

carvedilol, (R)-isomer

carvedilol, (S)-isomer

carvedilol, 14C-labeled

Emtricitabine

approved, investigational

Phase 4, Phase 3

394

143491-57-0

60877

Synonyms:

(-)-(2R,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

(-)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

(-)-.beta.-L-FTC

(-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine

(-)-2'-Deoxy-5-fluoro-3'-thiacytidine

(-)-FTC

(-)-beta-2',3'-Dideoxy-5-fluoro-3'-thiacytidine

(-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine

(-)-cis-4-amino-5-Fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one

(-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one

(2R-cis)-4-Amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone

(2R-cis)-4-amino-5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone

.beta.-L-(-)-(2R,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

1-(2-(Hydroxymethyl)oxathiolan-5-yl)-5-fluorocytosine

143491-54-7

143491-57-0

145213-48-5

2',3',5-FTC

2',3'-Dideoxy-5-fluoro-3'-thiacytidine

2'-Deoxy-5-fluoro-3'-oxa-4'-thiocytidine

2'-Deoxy-5-fluoro-3'-thiacytidine

2-FTC

3'-Thia-2'.3'-dideoxy-5-fluorocytidine

4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one

4-Amino-5-fluoro-1-[(2R,5S)-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

4-amino-5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one

4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine

5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine

5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)[1,3]oxathiolan-5-yl]cytosine

524W91

AC1L1U3I

AC1Q4KUB

BW 1592

BW 524W91

BW-524W91

BW524W91

C122114

C12599

C8H10FN3O3S

CHEBI:31536

CHEMBL885

CID60877

Coviracil

Coviracil(TM)

D01199

DB00879

DRG-0208

Emtricitabin

Emtricitabina

Emtricitabine

Emtricitabine (JAN/USAN/INN)

Emtricitabinum

Emtriva

Emtriva (TN)

Emtriva(TM)

FT-0080009

HMS2089I05

HSDB 7337

LS-135838

LS-173184

NCGC00164564-01

RCV

Racivir

SBB066061

TL8000958

UNII-G70B4ETF4S

ZINC03629271

beta-L-2',3'-dideoxy-5-fluoro-3'-thiacytidine

dOTFC

emtricitabine

Ritonavir

approved, investigational

Phase 4, Phase 2, Phase 3

850

155213-67-5

392622

Synonyms:

1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate

155213-67-5

1hxw

1sh9

5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S)-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate

5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate

538, ABT

A-84538

ABBOTT-84538

ABT 538

ABT 84538

ABT-538

ABT538

AC-733

AC1L94GB

AKOS000280930

Abbott 84538

BIDD:GT0387

BIDD:PXR0023

Bio-0093

C07240

C37H48N6O5S2

CHEBI:45409

CHEMBL163

CID392622

CPD000466395

D00427

D019438

DB00503

DRG-0244

FT-0082824

HMS2051B08

HSDB 7160

LS-148860

MLS000759541

MLS001424063

MolPort-000-883-877

N-[(2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl]-N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-L-valinamide

NCGC00159462-02

NSC693184

Norvir

Norvir (TM)

Norvir (TN)

Norvir Sec

RIT

RTV

Ritonavir

Ritonavir (JAN/USAN/INN)

Ritonavir [USAN]

Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS.

Ritonavirum

S1185_Selleck

SAM001246783

SMR000466395

STK634209

ZINC03944422

ritonavir

Rifampicin

approved

Phase 4, Phase 3, Phase 2

303

13292-46-1

5458213, 5381226

Synonyms:

1-b]furan-21-yl acetate

13292-46-1

3-(((4-Methyl-1-piperazinyl)imino)-methyl)rifamycin

3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV

3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin sv

3-(4-Methylpiperazinyliminomethyl)-rifamycin SV

3-(4-Methylpiperazinyliminomethyl)rifamycin SV

3-([(4-Methyl-1-piperazinyl)imino]methyl)rifamycin SV

3-[(4-Methyl-1-piperazinyl)iminomethyl]rifamycin SV

3-[[(4-Methyl-1-piperazinyl)imino]-methyl]rifamycin

46713_FLUKA

46713_RIEDEL

62534-43-4

8-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV

8-(4-Methylpiperazinyliminomethyl) rifamycin SV

8-[[(4-Methyl-1-piperazinyl)imino[methyl]rifamycin

8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin sv

8-[[(4-Methylpiperazinyl)imino]methyl]rifamycin sv

83907_FLUKA

83907_SIGMA

8CI)

AZT + Rifampin

Abrifam

Archidyn

Arficin

Arzide

BA-41166E

BIDD:PXR0014

BPBio1_000561

BSPBio_000509

Ba 41166

Ba 41166/E

Benemicin

Benemycin

Bio-0621

C06688

C43H58N4O12

CAS-13292-46-1

CCRIS 551

CHEBI:28077

CHEBI:455936

CHEMBL180

CID5381226

CID5388984

CID5458213

CID5702112

CID6604339

CID6708473

CID6842115

CID6912767

CID6913622

CPD001906767

D00211

DB01045

DRG-0109

Dione 21-acetate

Dipicin

DivK1c_000550

Doloresum

EINECS 236-312-0

Eremfat

Famcin

Fenampicin

HMS1569J11

HMS1920P08

HMS2089F12

HMS2092G09

HMS501L12

HSDB 3181

KBio1_000550

KBio2_000919

KBio2_003487

KBio2_006055

KBio3_003018

KBioGR_001780

KBioSS_000919

L-5103

L-5103 Lepetit

LS-7689

MLS000028552

MLS001148237

MLS001333745

MolPort-000-767-051

MolPort-002-513-586

MolPort-003-666-281

MolPort-006-395-891

NCGC00016699-01

NCGC00017365-01

NCGC00018178-01

NCGC00022678-03

NCGC00022678-04

NCGC00022678-05

NCGC00160500-01

NCI60_000309

NINDS_000550

NSC 113926

NSC-113926

NSC113926

Piperine & Rifampicin

Prestwick0_000525

Prestwick1_000525

Prestwick2_000525

Prestwick3_000525

Prestwick_833

R-Cin

R/AMP

R0079

R3501_SIAL

R3501_SIGMA

R5777_SIGMA

R7382_SIGMA

RAMP

RFP

RMP

Ramp

Reserpine & Rifampicin

Rfamipicin

Rifa

Rifadin

Rifadin (TN)

Rifadin I.V

Rifadin I.V.

Rifadin IV

Rifadin Iv

Rifadin, Rimactane, Rifampicin, Rifampin

Rifadine

Rifagen

Rifaldazin

Rifaldazine

Rifaldin

Rifam

Rifamicin AMP

Rifamor

Rifampicin

Rifampicin & EEP

Rifampicin & Propolis

Rifampicin (JP15/INN)

Rifampicin SV

Rifampicin [INN:BAN:JAN]

Rifampicin sodium

Rifampicina

Rifampicina [INN-Spanish]

Rifampicine

Rifampicine [French]

Rifampicinum

Rifampicinum [INN-Latin]

Rifampin

Rifampin (USP)

Rifampin [USAN]

Rifamsolin

Rifamycin

Rifamycin AMP

Rifamycin Amp

Rifaprodin

Rifcin

Rifinah

Rifobac

Rifoldin

Rifoldine

Riforal

Rimactan

Rimactane

Rimactane (TN)

Rimactazid

Rimactin

Rimactizid

Rimazid

Rimycin

Rofact

S1764_Selleck

SAM002264646

SMR000058322

SMR000653525

SPBio_002430

SPECTRUM1500529

STK080143

Sinerdol

Spectrum3_001837

Spectrum4_001250

Spectrum5_002018

Spectrum_000439

TNP00313

Tubocin

UNII-VJT6J7R4TR

WLN: V1 WQ A&1 E&1 E1UN- AT6N DNTJ D1

nchembio884-comp4

rifampin

Tenofovir

approved, investigational

Phase 4, Phase 3, Phase 2

666

147127-20-6

464205

Synonyms:

(R)-9-(2-Phosphonomethoxypropyl)adenine

(R)-9-(2-Phosphonylmethoxypropyl)adenine

(R)-PMPA

147127-20-6

206184-49-8

AC-760

AC1LA9BO

Anh. tenofovir

Anhydrous tenofovir

Apropovir

CHEBI:45809

CHEMBL483

CID464205

D,L-Tenofovir

DB00300

GNA & Tenofovir

GS 1275

GS 1278

GS1278

HHA & Tenofovir

KS-5021

MolPort-003-850-411

NCGC00167535-01

PMPA

PMPA-(R)

Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Galanthus nivalis agglutinin (GNA)

Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Hippeastrum hybrid agglutinin( HHA)

Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- (9CI)

Phosphonic acid, [[2-(6-amino-9H-purin-9

S1401_Selleck

TDF

TFV

Tenefovir

Tenofovir

Tenofovir (anh.)

Tenofovir Disoproxil Fumarate

Tenofovir disoproxil

Tenofovir disoproxil fumarate

UNII-99YXE507IL

Viread

Viread, Tenofovir

[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid

Lopinavir

approved

Phase 4, Phase 2, Phase 3

342

192725-17-0

92727

Synonyms:

(1S-(1R*(R*),3R*,4R*))-N-(4-(((2,6-Dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide

(2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide

(alphaS)-Tetrahydro-N-((alphaS)-alpha-((2S,3S)-2-hydroxy-4-phenyl-3-(2-(2,6-xylyloxy)acetamido)butyl)phenethyl)-alpha-isopropyl-2-oxo-1(2H)-pyrimidineacetamide

1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-alpha-(1-methylethyl)-2-oxo-, (alphaS)- (9CI)

192725-17-0

1mui

2o4s

2q5k

2rkf

2rkg

A 157378

A 157378.0

A-157378-0

A-157378.0

AB1

ABT 157378

ABT 378

ABT-378

ABT-378, LOPINAVIR

AC1L3OPJ

AIDS032937

Aluviran

C12871

C37H48N4O5

CHEBI:40456

CHEMBL729

CID92727

D01425

DB01601

Kaletra

Koletra

LPV

LS-173766

Lopinavir

Lopinavir (JAN/USAN/INN)

Lopinavir [USAN:INN:BAN]

MolPort-003-848-410

N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide

N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE

NCGC00164576-01

NCGC00164576-02

RS-346

S1380_Selleck

SID124893167

SID144205757

SID50111692

UNII-2494G1JF75

a-157378-0

a-157378.0

Zidovudine

approved

Phase 4, Phase 3, Phase 2

491

30516-87-1

35370

Synonyms:

-Azido-3&prime

-deoxythymidine

1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)thymine

3&prime

3' Azido 2',3' Dideoxythymidine

3' Azido 3' deoxythymidine

3'-Azido-2',3'-Dideoxythymidine

3'-Azido-3'-deoxythymidine

3'-Azido-3'-deoxythymidine & Concanavalin A

3'-Azido-3'-deoxythymidine & Erythropoietin

3'-Azido-3'-deoxythymidine & Heteropolyoxotungstate PM-19

3'-Azido-3'-deoxythymidine & Interleukin-1

3'-Azido-3'-deoxythymidine & Interleukin-2

3'-Azido-3'-deoxythymidine & Interleukin-6

3'-Azido-3'-deoxythymidine & Lithium & Erythropoietin

3'-Azido-3'-deoxythymidine & Lithium & Interleukin-1

3'-Azido-3'-deoxythymidine & Lithium & Interleukin-6

3'-Azido-3'-deoxythymidine & Lymphoblastoid Interferon

3'-Azido-3'-deoxythymidine & Sho-Saiko-To

3'-Azido-3'-deoxythymidine (AIDS)

3'-Azido-3'deoxythymidine & Interferon .alpha.

3'-Azidothymidine

3'-Deoxy-3'-azidothymidine

3'-azido-3'-deoxythymidine, AZT

3-Azido-3-deoxythymidine

30516-87-1

399024-19-2

A2169_SIGMA

AC1L1TKL

AC1Q2OEK

AZT

AZT & CD4(178)-PE 40

AZT & Colony-stimulating factor 2

AZT & Concanavalin A (ConA)

AZT & EPO

AZT & GM-CSF

AZT & HPA

AZT & IFN.alpha.

AZT & IL-1

AZT & IL-2

AZT & IL-6

AZT & Interferon-.alpha.-2

AZT & Li & EPO

AZT & Li & GM-CSF

AZT & Li & IL-1

AZT & Li & IL-6

AZT & Lymphoblastoid Interferon

AZT & NP (from PHCA or HSA)

AZT & PM-19

AZT & SST

AZT & rIFN.alpha.2

AZT & rsCD4 & rIFN.alpha.A

AZT & rsT4

AZT & sCD4

AZT & srCD4

AZT (Antiviral)

AZT Antiviral

AZT TRANSPLACENTAL CARCINOGENESIS STUDY

AZT+PRO 140

AZT, Antiviral

Antiviral AZT

Apo-Zidovudine

Azidothymidine

Aztec

BB_NC-1012

BPBio1_000403

BRD-K72903603-001-04-6

BSPBio_000365

BSPBio_003153

BW A509U

BW-A 509U

BW-A-509U

BW-A509U

BWA 509U

BWA-509U

BWA509U

C07210

CCRIS 105

CHEBI:10110

CHEBI:127307

CHEMBL129

CID35370

CPD000058351

Compound S

Cpd S

D00413

D015215

DB00495

DRG-0004

DS-4152 & AZT

DivK1c_000524

HMS1921J20

HMS2090G11

HMS2092D06

HMS501K06

HSDB 6515

IDI1_000524

Interferon AD + 3'-azido-3'-deoxythymidine

Intron A & AZT

K7 [P Ti2 W10 O40]

KBio1_000524

KBio2_001828

KBio2_004396

KBio2_006964

KBio3_002653

KBioGR_000703

KBioSS_001828

LS-1159

Liposomal AZT-SN-1

Liposomal AZT-SN-3

MLS000028548

MLS001055351

MLS001076358

MLS002153202

MLS002222249

Met-SDF-1.beta. & AZT

Met-SDF-1.beta. & Zidovudine

MolPort-002-507-286

NCGC00023945-03

NCGC00023945-04

NCGC00023945-05

NCGC00023945-08

NCGC00178237-01

NCGC00178237-02

NINDS_000524

NSC 602670

Novo-Azt

PC-SOD+AZT

Prestwick3_000333

Propolis+AZT

Racemic Liposomal AZT

Retrovir

Retrovir (TN)

Retrovir(TM)

SAM002548971

SMR000058351

SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle)

SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle)

SPBio_000834

SPECTRUM1502109

STK801891

Spectrum2_000927

Spectrum3_001507

Spectrum4_000332

Spectrum5_001101

Spectrum_001348

UNII-4B9XT59T7S

ZDV

ZIDOVUDINE [AZT]

ZINC03779042

ZVD

Zidovudin

Zidovudina

Zidovudina [Spanish]

Zidovudine

Zidovudine (JAN/USP/INN)

Zidovudine EP III

Zidovudine [USAN:INN:BAN:JAN]

Zidovudine+PRO 140

Zidovudinum

Zidovudinum [Latin]

antiviral

azidodeoxythymidine

rIFN-beta seron & AZT

racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle)

zidovudin

zidovudine

Enalapril

approved

Phase 4

112

75847-73-3

5362032, 40466924

Synonyms:

(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid

(S)-1-(N-(1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline

(S)-1-{(S)-2-[1-((S)-ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid

1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester

75847-73-3

AC1NTUS5

Analapril

BIDD:GT0751

BPBio1_000340

BSPBio_000308

BSPBio_003035

Bonuten

C06977

CAS-76095-16-4

CHEBI:116847

CHEBI:4784

CHEMBL578

CID5388962

D07892

DivK1c_000408

Enalapril

Enalapril (INN)

Enalapril (TN)

Enalapril Bp

Enalapril Maleate

Enalapril Richet

Enalaprila

Enalaprila [INN-Spanish]

Enalaprilat

Enalaprilum

Enalaprilum [INN-Latin]

Gadopril

HMS2090E08

IDI1_000408

KBio1_000408

KBio2_001787

KBio2_004355

KBio2_006923

KBio3_002535

KBioGR_000355

KBioSS_001787

Kinfil

LS-190651

MolPort-002-885-877

N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline

N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl-L-proline

NCGC00016932-01

NCGC00021569-04

NCGC00021569-05

NCGC00021569-06

NINDS_000408

Prestwick3_000314

SPBio_001349

Spectrum2_001455

Spectrum3_001478

Spectrum4_000008

Spectrum5_001107

Spectrum_001307

Vaseretic

Vasotec

Vasotec IV

enalapril

Warfarin

approved

Phase 4

422

81-81-2

6691, 54678486

Synonyms:

(-)-Warfarin

(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone

(S)-Warfarin

(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin

(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine

1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone

200 Coumarin

200 coumarin

3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin

3-(Acetonylbenzyl)-4-hydroxycoumarin

3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin

3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin

3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin

4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine

4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin

4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine

4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin

4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one

4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one

4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin

4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine

4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine

4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine

45706_FLUKA

45706_RIEDEL

4oh-coumarin deriv.

5543-56-6

5543-57-7

81-81-2

A2250_FLUKA

A2250_SIGMA

AC-15978

AC1L1N37

AC1Q6AN3

AR-1E2310

Arab Rat Death

Arab rat death

Arab rat deth

Athrombin

Athrombin-K

Athrombin-k

Athrombine-K

Athrombine-k

BRD-A24514565-001-02-2

BRD-A24514565-236-01-6

BRN 1293536

BSPBio_002026

Bio-0586

Brumolin

C01541

C19H16O4

CBDivE_002127

CBDivE_013236

CBKinase1_000192

CBKinase1_012592

CHEBI:10033

CHEMBL1464

CID6691

CO-Rax

Caswell No. 903

Choice

Choice (TN)

Co-Rax

Co-rax

Compound 42

Coumadin

Coumadin Tabs

Coumafen

Coumafene

Coumafene [French]

Coumaphen

Coumaphene

Coumarins

Coumefene

Cov-R-Tox

Cov-R-tox

D-Con

D08682

DB00682

DL-3-(alpha-acetonylbenzyl)-4-hydroxycoumarin

Dethmor

Dethnel

Dicusat E

Dicusat e

DivK1c_000444

EINECS 201-377-6

EINECS 226-907-3

EPA Pesticide Chemical Code 086002

Eastern states duocide

Fasco fascrat powder

Frass-Ratron

Frass-ratron

HMS1921K07

HMS2092C20

HMS501G06

HSDB 1786

I14-0958

IDI1_000444

Jantoven

KBio1_000444

KBio2_000674

KBio2_003242

KBio2_005810

KBio3_001526

KBioGR_000901

KBioSS_000674

Killgerm sewarin p

Kumader

Kumadu

Kumatox

Kypfarin

LS-55083

Latka 42

Latka 42 [Czech]

Liqua-tox

MLS001304042

Maag Rattentod Cum

Maag rattentod cum

Mar-Frin

Mar-frin

Marevan

Martin'S mar-frin

Martin's mar-frin

Maveran

MolPort-001-787-822

Mouse pak

NCGC00094810-01

NCGC00094810-02

NCGC00159398-03

NCGC00178855-01

NINDS_000444

NSC 59813

NSC59813

PS104_SUPELCO

Panwarfin

Place-Pax

Place-pax

Prothromadin

RAX

RCR grey squirrel killer concentrate

RCRA waste no. P001

Rat & mice bait

Rat and mice bait

Rat-B-gon

Rat-Gard

Rat-Kill

Rat-Mix

Rat-O-cide #2

Rat-O-cide no. 2

Rat-Ola

Rat-Trol

Rat-a-way

Rat-alpha-way

Rat-b-gon

Rat-beta-gon

Rat-gard

Rat-kill

Rat-mix

Rat-o-cide #2

Rat-ola

Rat-trol

Ratorex

Ratox

Ratoxin

Ratron

Ratron G

Ratron g

Rats-no-more

Ratten-Koederrohr

Ratten-koederrohr

Rattenstreupulver Neu Schacht

Rattenstreupulver neu schacht

Rattenstreupulver new schacht

Rattentraenke

Rattunal

Rcra waste number P001

Ro-Deth

Ro-deth

Rodafarin

Rodafarin C

Rodafarin c

Rodex

Rodex blox

Rosex

Rough & ready mouse mix

Rough and ready mouse mix

SMP1_000316

SMR000718754

SPBio_000870

SPECTRUM1500613

STK364490

Sakarat

Sewarin

Sofarin

Solfarin

Sorexa Plus

Sorexa plus

Spectrum2_000935

Spectrum3_000583

Spectrum4_000381

Spectrum5_001751

Spectrum_000194

Spray-trol brand roden-trol

Temus W

Temus w

Tintorane

Tox-Hid

Tox-hid

Twin light rat away

UNII-5Q7ZVV76EI

Vampirinip II

Vampirinip III

Vampirinip iii

W.A.R.F. 42

WARF compound 42

WLN: T66 BOVJ DYR&1V1 EQ

Waran

Warf 10

Warf 42

Warfarat

Warfarin (INN)

Warfarin (and salts of)

Warfarin Plus

Warfarin Q

Warfarin Sodium

Warfarin [BSI:ISO]

Warfarin [INN:BAN]

Warfarin plus

Warfarin plus [discontinued]

Warfarin sodium

Warfarin titrated to an INR of 2.5-3.0

Warfarin(R)

Warfarina

Warfarina [INN-Spanish]

Warfarine

Warfarine [INN-French]

Warfarine [ISO-French]

Warfarinum

Warfarinum [INN-Latin]

Warficide

Warfilone

Zoocoumarin

Zoocoumarin [Netherlands and USSR]

Zoocoumarin [Russian]

delta-Con

nchembio.307-comp19

rac-Warfarin

warfarin

Aspirin

approved

Phase 4

1029

50-78-2

2244

Synonyms:

11126-35-5

11126-37-7

1oxr

2-(ACETYLOXY)benzoic acid

2-(Acetyloxy)benzoate

2-(Acetyloxy)benzoic acid

2-Acetoxybenzenecarboxylic acid

2-Acetoxybenzoate

2-Acetoxybenzoic acid

2-Carboxyphenyl acetate

2349-94-2

26914-13-6

50-78-2

7 Select Adult Chewable Aspirin

7 Select Aspirin

8-hour Bayer

98201-60-6

A 5376

A.S.A

A.S.A.

A.S.A. Empirin

A.S.A. empirin

A2093_SIGMA

A3160_SIGMA

A5376_SIGMA

A6810_SIGMA

AB1003266

AC 5230

AC1L1D8U

AC1Q1LA0

ACETYLSALICYLIC ACID

AI3-02956

AIN

AKOS000118884

ASA

Acenterine

Acesal

Acetal

Acetard

Aceticyl

Acetilsalicilico

Acetilum acidulatum

Acetisal

Acetol

Acetonyl

Acetophen

Acetosal

Acetosalic acid

Acetosalin

Acetoxybenzoic acid

Acetylin

Acetylsal

Acetylsalicylate

Acetylsalicylic acid

Acetylsalicylsaeure

Acetylsalicylsaure

Acetylsalycilic acid

Acetyonyl

Acetysal

Acetysalicylic acid

Acide 2-(acetyloxy)benzoique

Acide acetylsalicylique

Acide acétylsalicylique

Acido O-acetil-benzoico

Acido acetilsalicilico

Acidum acetylsalicylicum

Acimetten

Acisal

Acylpyrin

Adiro

Adult Chewable Low Dose Aspirin

Adult Low Dose Aspirin

Adult Low Dose Aspirin Enteric Safety Coated

Adult Low Dose Enteric Coated Aspirin

Adult Low Strength Aspirin

Aloxiprimum

Asacard

Asagran

Asaphen

Asatard

Ascoden-30

Ascriptin Maximum Strength Buffered Aspirin

Ascriptin Regular Strength Buffered Aspirin

Aspalon

Aspec

Aspergum

Aspi-cor

Aspir Low

Aspir-Mox

Aspirdrops

Aspirin

Aspirin (JP15/USP)

Aspirin 81 Mg

Aspirin 81 Mg Low Dose

Aspirin Adult Low Dose

Aspirin Adult Low Strength

Aspirin Adult Low Strength Aspirin

Aspirin Adult low strength

Aspirin Chewable Low Dose

Aspirin Delayed Release

Aspirin EC

Aspirin EXTRA STRENGTH

Aspirin Ec

Aspirin Enteric

Aspirin Enteric Coated

Aspirin Enteric Coated Low Dose

Aspirin Enteric Safety Coated

Aspirin Enteric Safety-Coated

Aspirin Low Dose

Aspirin Low Dose Chewable

Aspirin Low Dose Enteric Coated

Aspirin Low Dose Safety Coated

Aspirin Low Strength

Aspirin Nsaid

Aspirin Regular Strength

Aspirin Regular Strength regular strength

Aspirin Regular strength

Aspirin Safety Coated

Aspirin Safety Coated Adult Low Dose

Aspirin Safety coated

Aspirin Thin coated

Aspirin [BAN:JAN]

Aspirin adult low dose

Aspirin adult low strength

Aspirin enteric safety coated

Aspirin low dose

Aspirin low dose chewable

Aspirin low dose enteric coated

Aspirin regular strength

Aspirina 03

Aspirine

Aspiring

Asprin

Aspro

Aspro Clear

Asteric

Azetylsalizylsaeure

Azetylsalizylsäure

BIDD:GT0118

BRN 0779271

Bay-e-4465

Bayer

Bayer Advanced Aspirin Extra Strength

Bayer Advanced Aspirin Regular Strength

Bayer Aspirin 8 Hour

Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange

Bayer Aspirin Regimen Regular Strength

Bayer Buffered

Bayer Chewable - Aspirin Regimen Low Dose Aspirin Cherry Flavored

Bayer Extra Strength Aspirin For Migraine Pain

Bayer Fast Release

Bayer Genuine Aspirin

Bayer Low Dose

Bayer Plus

Bayer Plus Extra Strength

Bayer Womens

Benaspir

Bi-prin

Bialpirina

Bialpirinia

Buffered Aspirin

Bufferin

Bufferin LOW DOSE BUFFERED ASPIRIN

C01405

CCRIS 3243

CHEBI:15365

CHEMBL25

CID2244

Caprin

Cardioaspirin

Cardioaspirina

Care One Aspirin

Cemirit

Chewable Adult Low Dose Aspirin

Chewable Aspirin

Chewable Low Dose Aspirin

Claradin

Clariprin

Colfarit

Contrheuma retard

Coricidin

Critical Care Aspirin To Go

Crystar

D00109

D001241

DB00945

Decaten

Delgesic

Dg Health Aspirin

Direct Safety Aspirin

Dispril

DivK1c_000555

Dolean pH 8

Duramax

ECM

EINECS 200-064-1

EU-0100038

Easprin

Easprin (TN)

Ec-81aspirin Enteric Coated

Ecolen

Ecotrin

Ecotrin Regular Strength

Empirin

Empirin with Codeine

Endosprin

Endydol

Enteric Aspirin

Enteric Coated Aspirin

Enteric Coated Aspirin Regular Strength

Enteric Coated Aspirin Regular strength

Enteric Coated Aspirin regular strength

Enteric Coated Asprin 81 Mg

Enteric Coated Low Dose Aspirin

Enteric Safety Coated Aspirin

Entericin

Enterophen

Enterosarein

Enterosarine

Entrophen

Equaline Aspirin

Equaline Aspirin adult low dose

Equate Aspirin

Equate Aspirin chewable

Extren

Fasprin

Flanax Aspirin Pain Reliever

Formucare Aspirin

Genuine Aspirin

Globentyl

Globoid

Good Neighbor Pharmacy Aspirin

Good Neighbor Pharmacy Aspirin Enteric Safety Coated

Good Neighbor Pharmacy Aspirin orange flavor chewable

Good Sense Aspirin

Good Sense Aspirin Enteric Safety Coated

HMS1920E13

HMS2090G03

HMS2091K13

HMS501L17

HSDB 652

Handy Solutions Genuine Aspirin Bayer

Health Mart Aspirin

Health Mart Regular Strength Enteric Coated Aspirin

Health Sense Adult Chewable Low Strength Aspirin

Health Sense Aspirin 81

Health Sense Ecpirin

Healthy Accents Aspirin

Helicon

Henry Schein Aspirin

I14-7505

IDI1_000555

Idragin

Istopirin

KBio1_000555

KBio2_001725

KBio2_002271

KBio2_004293

KBio2_004839

KBio2_006861

KBio2_007407

KBio3_002149

KBio3_002751

KBioGR_000398

KBioGR_002271

KBioSS_001725

KBioSS_002272

Kapsazal

Kroger Value Aspirin

Kyselina 2-acetoxybenzoova

Kyselina acetylsalicylova

LS-143

Leader Aspirin

Leader Cardinal Health Aspirin

Leader Low Dose Aspirin

Levius

Lopac-A-5376

Lopac0_000038

Low Dose Adult Aspirin

Low Dose Aspirin

Low Dose Aspirin 81 Mg Safety Coated

Low Dose Aspirin Enteric Safety Coated

Low Dose Asprin

Low Dose Chewable Aspirin

Low Dose Miniprin Enteric Safety Coated

Low Dose Pain Relief Aspirin

Low Strength Chewable Aspirin

Low-dose Aspirin

MLS001055329

MLS001066332

MLS001336045

MLS001336046

Magnecyl

Measurin

Medi First Plus Aspirin

Medi-first Aspirin

Medique Aspirin

Medisyl

Micristin

Micro-coated Aspirin

Miniprin

MolPort-000-871-622

NCGC00015067-01

NCGC00015067-04

NCGC00015067-09

NCGC00090977-01

NCGC00090977-02

NCGC00090977-03

NCGC00090977-04

NCGC00090977-05

NCGC00090977-06

NCGC00090977-07

NCI60_002222

NINDS_000555

NSC 27223

NSC27223

NSC406186

Neuronika

North Aspirin

Novasen

Novid

Nu-seals

Nu-seals aspirin

O-(Acetyloxy)benzoate

O-(Acetyloxy)benzoic acid

O-Acetoxybenzoate

O-Acetoxybenzoic acid

O-Acetylsalicylic acid

O-Carboxyphenyl acetate

O-accetylsalicylic acid

O-acetylsalicylic acid

PL-2200

Pain Relief Aspirin

Pain Relief Aspirin Low Dose

Persistin

Pharbest Aspirin 325mg

Pharbest Regular Strength Aspirin

Pharmacin

Pirseal

Plus Pharma NSAID 325 mg

Plus Pharma Nsaid Aspirin

Polopirin

Polopiryna

Premaspin

R16CO5Y76E [UNII]

Rapid Comfort Aspirin

Regular Strength Aspirin

Regular Strength Aspirin Ec

Regular Strength Buffered Aspirin

Regular Strength Enteric Aspirin

Regular Strength Enteric Coated Aspirin

Regular Strength Pain Relief

Regular Strength Tri-buffered Aspirin

Rexall Aspirin

Rheumin tabletten

Rheumintabletten

Rhodine

Rhonal

Ronal

Rugby Aspirin

Rx Act Aspirin

S-211

SMR000059138

SP 189

SPBio_001838

SPECTRUM1500130

ST075414

Safety Coated Aspirin

Safety Coated Enteric Aspirin

Salacetin

Salcetogen

Saletin

Salicylic acid acetate

Salicylic acid, acetate

Salospir

Smart Health Aspirin regular strength

Smart Sense Aspirin

Solfrin

Solprin

Solprin acid

Solpyron

Solupsan

Solves - Aspirin Cherry

Spectrum2_001899

Spectrum3_001295

Spectrum4_000099

Spectrum5_000740

Spectrum_001245

Spira-Dine

St. Joseph

St. Joseph Aspirin for Adults

St. Joseph Chewable Aspirin

St. Joseph Safety Coated Aspirin

Sunmark Aspirin

Sunmark Aspirin Regular Strength

Sunmark Aspirin adult low strength

Sunmark Aspirin low dose

Supac

Tasprin

Temperal

Toldex

Topcare Aspirin

Tri-buffered Aspirin

Triaminicin

Triple-sal

UNII R16CO5Y76E

UNII-R16CO5Y76E

UNII=R16CO5Y76E

UNM-0000306102

Uncoated Aspirin

Value Pharma Aspirin Pain Reliever

Value Pharmapain Reliever Extra Strength

Vanquish

WLN: QVR BOV1

XAXA

Xaxa

Yasta

ZORprin

Zee Aspirin

aspirin

cMAP_000006

component of Midol

component of Synirin

nchem.859-comp6

o-Acetoxybenzoic acid

o-Carboxyphenyl acetate

o-acetoxybenzoic acid

o-carboxyphenyl acetate

ácido acetilsalicílico

Isoniazid

approved

Phase 4, Phase 3, Phase 2

142

54-85-3

3767

Synonyms:

37271-10-6

4-pyridinecarbohydrazide

41466-07-3

5015 R.P

5015 R.P.

5015 RP

54-85-3

62229-51-0

7640-37-1

AB00052025

AC1L1GNZ

AC1Q54UP

AC1Q54UQ

AI3-23936

AKOS000119062

AZT + Isoniazid

Abdizide

Andrazide

Anidrasona

Antimicina

Antituberkulosum

Armacide

Armazid

Armazide

Atcotibine

Azuren

BB_SC-6246

BIDD:GT0140

BP 5015

BPBio1_000025

BPBio1_001322

BSPBio_000021

BSPBio_002204

Bacillin

Biomol-NT_000288

C07054

C6H7N3O

CAS-54-85-3

CCRIS 351

CHEBI:6030

CHEMBL64

CID3767

CPD000059082

Cedin

Cedin (Aerosol)

Cemidon

Chemiazid

Chemidon

Continazine

Cortinazine

Cotinazin

Cotinizin

D00346

D007538

DB00951

Defonin

Dibutin

Diforin

Dinacrin

Ditubin

DivK1c_000070

Dow-Isoniazid

EINECS 200-214-6

Ebidene

Eralon

Ertuban

Eutizon

Evalon

FRS-3

FSR 3

FSR-3

Fetefu

Fimalene

GINK

HIA

HMS1568B03

HMS1920H09

HMS2089I16

HMS2091N19

HMS500D12

HSDB 1647

Hid rasonil

Hidranizil

Hidrasonil

Hidrulta

Hidrun

Hycozid

Hydra

Hydrazid

Hydrazide

Hyozid

Hyzyd

I.A.I

I.A.I.

I0138

I14-9731

I3377_FLUKA

I3377_SIGMA

IDI1_000070

INH

INHd20

Ido-tebin

Idrazil

In-73

Inah

Inh-Burgthal

Inizid

Iscotin

Isidrina

Ismazide

Isobicina

Isocid

Isocidene

Isocotin

Isohydrazide

Isokin

Isolyn

Isonerit

Isonex

Isoniacid

Isoniazid

Isoniazid & EEP

Isoniazid & Propolis

Isoniazid SA

Isoniazida

Isoniazide

Isoniazidum

Isonicazide

Isonicid

Isonico

Isonicotan

Isonicotil

Isonicotinhydrazid

Isonicotinic acid hydrazide

Isonicotinic hydrazide

Isonicotinohydrazide

Isonicotinoyl hydrazide

Isonicotinoylhydrazide

Isonicotinsaeurehydrazid

Isonicotinyl hydrazide

Isonicotinyl hydrazine

Isonicotinylhydrazine

Isonide

Isonidrin

Isonikazid

Isonilex

Isonin

Isonindon

Isonirit

Isoniton

Isonizida

Isonizide

Isopyrin

Isotamine

Isotebe

Isotebezid

Isotinyl

Isozid

Isozide

Isozyd

KBio1_000070

KBio2_001333

KBio2_003901

KBio2_006469

KBio3_001424

KBioGR_000423

KBioSS_001333

L 1945

LANIZID

LS-205

Laniazid

Laniazid (TN)

Laniozid

MLS000069444

MLS001055327

MolPort-000-141-557

Mybasan

NCGC00016244-01

NCGC00016244-02

NCGC00022648-03

NCGC00022648-04

NCGC00022648-05

NCGC00022648-06

NINDS_000070

NSC 9659

NSC9659

Neo-Tizide

Neoteben

Neoxin

Neumandin

Nevin

Niadrin

Nicazide

Nicetal

Nicizina

Niconyl

Nicotibina

Nicotibine

Nicotisan

Nicozide

Nidaton

Nidrazid

Nikozid

Niplen

Nitadon

Niteban

Nitebannsc 9659

Nydrazid

Nyscozid

Oprea1_396155

Pelazid

Percin

Phthisen

Preparation 6424

Prestwick0_000161

Prestwick1_000161

Prestwick2_000161

Prestwick3_000161

Prestwick_578

Pycazide

Pyreazid

Pyricidin

Pyridicin

Pyridine-4-carboxylic acid hydrazide

Pyrizidin

RP 5015

RP-5015

RU-EF-Tb

RY-EF-Tb

Raumanon

Razide

Retozide

Rifamate

Rimicid

Rimifon

Rimiphone

Rimitsid

Robiselin

Robisellin

Roxifen

S1937_Selleck

SAM002554904

SMR000059082

SPBio_000094

SPBio_001942

SPECTRUM1500355

STK086288

Sanohidrazina

Sauterazid

Sauterzid

Spectrum2_000107

Spectrum3_000472

Spectrum4_000022

Spectrum5_000876

Spectrum_000853

Stanozide

TB-Phlogin

TB-Razide

TB-Vis

Tebecid

Tebenic

Tebexin

Tebilon

Tebos

Teebaconin

Tekazin

Tibazide

Tibemid

Tibiazide

Tibinide

Tibison

Tibivis

Tibizide

Tibusan

Tisin

Tisiodrazida

Tizide

Tubazid

Tubazide

Tubeco

Tubecotubercid

Tuberian

Tubicon

Tubilysin

Tubizid

Tubomel

Tyvid

UNII-V83O1VOZ8L

Unicocyde

Unicozyde

Usaf cb-2

Vazadrine

Vederon

WLN: T6NJ DVMZ

ZINC00001590

Zidafimia

Zinadon

Zonazide

bacillen

bp 5 015

isoco tin

isoniazid

isozid e

nchembio884-comp3

nidra zid

rimif on

tebemid

tubercid

Pyrazinamide

approved

Phase 4, Phase 3, Phase 2

98-96-4

1046

Synonyms:

2-Carbamylpyrazine

2-Pyrazinecarboxamide

2-carbamyl pyrazine

2-carbamylpyrazine

2-pyrazinecarboxamide

5-25-04-00178 (Beilstein Handbook Reference)

82612_FLUKA

98-96-4

AB00052083

AC-907/25014068

AC1L1ALT

AC1Q4ZGM

AKOS000120280

AZT + Pyrazinamide combination

Aldinamid

Aldinamide

BB_SC-1250

BIDD:GT0228

BPBio1_000515

BRN 0112306

BSPBio_000467

BSPBio_002572

Braccopiral

C01956

C5H5N3O

CAS- 98-96-4

CCRIS 545

CHEBI:45285

CHEMBL614

CID1046

CPD000036662

Corsazinmid

D-50

D-50 (VAN)

D00144

D011718

DB00339

DRG 0124

Dipimide

DivK1c_000241

EINECS 202-717-6

EU-0101011

Eprazin

Farmizina

HMS1569H09

HMS1920N08

HMS2092E09

HMS500M03

HSDB 3576

I14-6758

IDI1_000241

InChI=1/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9

Isopas

KBio1_000241

KBio2_001382

KBio2_003950

KBio2_006518

KBio3_001792

KBioGR_001851

KBioSS_001382

LS-2053

Lopac-P-7136

Lopac0_001011

Lynamide

MK 56

MLS000069730

MLS002222347

MolPort-001-770-770

NCGC00015833-01

NCGC00015833-02

NCGC00015833-05

NCGC00015833-10

NCGC00090695-01

NCGC00090695-03

NCGC00090695-04

NCGC00090695-05

NCGC00090695-06

NCGC00090695-07

NCI-C01785

NINDS_000241

NSC 14911

NSC14911

Novamid

P 7136

P ezetamid

P0633

P7136_SIGMA

PZA

Pezetamid

Pharozinamide

Piraldina

Pirazimida

Pirazinamid

Pirazinamida

Pirazinamida [INN-Spanish]

Pirazinamide

Pirazinamide [DCIT]

Pirilene

Prazina

Prestwick0_000514

Prestwick1_000514

Prestwick2_000514

Prestwick3_000514

Prestwick_811

Pyrafat

Pyramide

Pyrazide

Pyrazinamdie

Pyrazinamid

Pyrazinamida

Pyrazinamide

Pyrazinamide (JP15/USP/INN)

Pyrazinamide (TN)

Pyrazinamide BP 2000

Pyrazinamide [INN:BAN:JAN]

Pyrazinamidum

Pyrazinamidum [INN-Latin]

Pyrazine carboxamide

Pyrazine carboxylamide

Pyrazineamide

Pyrazinecarboxamide

Pyrazinecarboxylic acid amide

Pyrazinoic acid am ide

Pyrazinoic acid amide

Pyrazinoic acid amide, Pezetamid, Pyrafat, Zinamide, Tebrazid, Pyrafat, Pyrazinamide

Pyrizinamide

Rifater

Rozide

S1762_Selleck

SAM002554927

SMR000036662

SPBio_001369

SPBio_002388

SPECTRUM1500518

STK801661

Spectrum2_001305

Spectrum3_001046

Spectrum4_001186

Spectrum5_001026

Spectrum_000902

T 165

Tebrazid

Tebrazio

Tisamid

UNII-2KNI5N06TI

Unipyranamide

WLN: T6N DNJ BVZ

ZINC00002005

Zinamide

Zinastat

pms-Pyrazinamide

pyrazinamide

pyrazine carboxylamide

pyrazine-2-carboxamide

pyrazinecarboxamide

pyrazinoic acid amide

Ethambutol

approved

Phase 4, Phase 3, Phase 2

74-55-5

3279, 14052

Synonyms:

(+)-(S,S)-2,2'-(1,2-Ethylenediimino)-di-1-butanol

(+)-2,2'-(Ethylenediimino)di-1-butanol

(+)-2,2'-(ethylenediimino)di-1-butanol

(+)-N,N'-Bis(1-(hydroxymethyl)propyl)ethylenediamine

(+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine

(+)-S,S-Ethambutol

(+)-S,S-ethambutol

(+)-ethambutol

(-)-(R,R)-2,2'-(1,2-Ethylenediimino)-di-1-butanol

(2'S)-2,2'-[Ethane-1,2-diyldi(imino)]dibutan-1-ol

(2R)-2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol

(2R)-2-[2-[[(2R)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol

(2S)-2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol

(2S)-2-[2-[[(2R)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol

(2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol

(2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol

(2S,7S)-2,7-Diethyl-3,6-diazaoctane-1,8-diol

(2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol

(R)-2,2'-(1,2-Ethanediyldiimino)bis-1-butanol

(S,R)-2,2'-(1,2-Ethylenediimino)-di-1-butanol

(S,S)-Ethambutol

(S,S)-ethambutol

1070-11-7

2,2'-(1,2-Ethylenediimino)-di-1-butanol

2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol

2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol

74-55-5

75343-56-5

AC1L1FKQ

AC1L230T

AC1L9YT2

AC1LABPH

AC1LAKIP

AC1LAKIS

AC1Q2C85

AC1Q2SHV

AC1Q77PZ

AR-1A7805

AR-1C2065

Aethambutolum

BPBio1_000105

BSPBio_000095

BSPBio_002012

C06984

C10H24N2O2

CAS-1070-11-7

CHEBI:4877

CHEMBL43824

CHEMBL44884

CID14052

CID3279

CID465436

CID470071

CID470072

CID504259

CL 40881 (dihydrochloride)

CPD000046147

D-2,2'-(Ethylenediimino)bis(1-butanol)

D-2,2'-(Ethylenediimino)di-1-butanol

D-Ethambutol

D-N,N'-Bis(1-hydroxymethylpropyl)ethylenediamine

D07925

DB00330

Dadibutol

Diambutol

DivK1c_000561

EINECS 200-810-6

EMB

Etambutol

Etambutol [INN-Spanish]

Etambutolo

Etambutolo [DCIT]

Ethambutol

Ethambutol & EEP

Ethambutol & Propolis

Ethambutol (INN)

Ethambutol HCL

Ethambutol Hydrochloride

Ethambutol [INN:BAN]

Ethambutol dihydrochloride

Ethambutol, (-)-isomer

Ethambutol, meso form

Ethambutol, racemic mixture

Ethambutolum

Ethambutolum [INN-Latin]

Etibi

HSDB 3078

IDI1_000561

KBio1_000561

KBio2_001538

KBio2_004106

KBio2_006674

KBio3_001232

KBioGR_001209

KBioSS_001538

KST-1A8084

LS-187119

LS-46537

MLS000082702

Miambutol

MolPort-002-507-956

MolPort-003-847-110

Myambutol

Myambutol (dihydrochloride)

NCGC00016560-01

NCGC00178864-01

NCGC00179661-01

NINDS_000561

NSC653313

Prestwick0_000028

Prestwick1_000028

Prestwick2_000028

Prestwick3_000028

Purderal

S,S-Ethambutol

SAM002589988

SMR000046147

SPBio_001167

SPBio_002016

STK711105

STOCK5S-98432

Servambutol

Servambutol (TN)

Spectrum2_001014

Spectrum3_000426

Spectrum4_000545

Spectrum5_000702

Spectrum_001058

Tibutol

UNII-8G167061QZ

d,N,N'-Bis(1-hydroxymethylpropyl)ethylenediamine

ethambutol

Etravirine

approved

Phase 4

269055-15-4

193962

Synonyms:

269055-15-4

394729-17-0

4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-benzonitrile

4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE

4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile

65B

AC1L4XC5

CHEBI:213138

CHEMBL308954

CID193962

D04112

DAPY deriv

DB07191

Diaminopyrimidine deriv

Etravirine

Etravirine (JAN/USAN/INN)

I06-1887

Intelence

Intelence (TN)

Intelence(TM)

R 165335

R-165335

R165335

R165335-TMC125

ST51053273

TMC 125

TMC-125

TMC-125/R-165335

TMC125

UNII-0C50HW4FO1

ZINC00602632

Darunavir

approved

Phase 4

198

635728-49-3, 206361-99-1

213039

Synonyms:

(3-((4-aminobenzenesulfonyl)isobutylamino)-1-benzyl-2-hydroxypropyl)carbamic acid hexahydrofuro(2,3-b)furan-3-yl ester

(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE

(3R,3AS,6ar)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N(1)-isobutylsulfanilamido)propyl)carbamate

(3R,3AS,6ar)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate

(3R,3AS,6ar)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate

(3R,3AS,6ar)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-neopentylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate

(3R,3aS,6aR)-Hexahydrofuro(2,3-b)furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N1-isobutylsulfanilamido)propyl)carbamate

(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N(1)-isobutylsulfanilamido)propyl)carbamate

(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate

(3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate

(3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-neopentylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate

206361-99-1

2f80

2f81

2f8g

2hs1

2hs2

2idw

2ien

3bvb

3cyw

3d1z

3d20

618109-00-5

AC1L4U4V

AIDS073035

CHEBI:367163

CHEMBL1323

CID213039

Carbamic acid, [(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester

D03656

DB01264

Darunavir

Darunavir (USAN/INN)

Darunavir [USAN]

Darunavirum

Darunavirum [INN-Latin]

Darunavirum [INN-latin]

LS-187026

LS-187772

LS-191295

MolPort-003-846-141

N-((1S,2R)-3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6-dioxabicyclo(3.3.0)oct-2-yloxy)carboxamide

Prezista

Prezista(TM)

TMC 114

TMC-114

TMC114

UIC 94017

UIC-94017

UIC-96017

UNII-YO603Y8113

[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate

[(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-1-((R)-phenylmethyl)-propyl]-carbamic acid (3R,3aS,6aR)-(hexahydro-furo[2,3-b]furan-3-yl) ester

[(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-1-((R)-phenylmethyl)-propyl]-carbamic acid (3R,3as,6ar)-(hexahydro-furo[2,3-b]furan-3-yl) ester

{(1S,2R)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid (3R,3aS,6aR)-(hexahydro-furo[2,3-b]furan-3-yl) ester

{(1S,2R)-3-[(4-amino-benzenesulfonyl)-isobutyl-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid (3R,3as,6ar)-(hexahydro-furo[2,3-b]furan-3-yl) ester

Pyridoxine

approved, nutraceutical

Phase 4, Phase 3, Phase 2

165

65-23-6

1054

Synonyms:

(5-hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphate

12001-78-4

2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine

2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridine

2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin

2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin [German]

2-Methyl-3-hydroxy-4,5-dihydroxymethylpyridine

2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine

2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl) pyridine

2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine

2-methyl-4,5-dimethylol-pyridin-3-ol

2B3E07D2-E4CC-4CC5-B085-6070BA01F9F0

3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride

3-Hydroxy-2-Picoline-4,5-dimethanol

3-Hydroxy-4,5-dihydroxymethyl-2-methylpyridine hydrochloride

3-Hydroxy-4,5-dimethylol-.alpha.-picoline hydrochloride

3-Hydroxy-4,5-dimethylol-alpha-picoline

3-Hydroxy-4,5-dimethylol-alpha-picoline hydrochloride

3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine

4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol

4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride

4,5-bis(hydroxymethyl)-2-methyl-3-pyridinol hydrochloride

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol

4,5-bis(hydroxymethyl)-2-methylpyridine-3-ol

4-Deoxypyridoxine 5'-phosphate

47862_SUPELCO

5-Hydroxy-6-methyl-3,4-pyridinedicarbinol hydrochloride

5-Hydroxy-6-methyl-3,4-pyridinedimethanol

5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride

5-Hydroxy-6-methyl-3,4-pyridinedimethanol, hydrochloride

58-56-0

58-56-0 (HCL)

58-56-0 (hydrochloride)

65-23-6

65-23-6 (Parent)

8059-24-3

85078-23-5

AC-12024

AC-14512

AC-907/25014218

AC1L1AMH

AC1L1LMI

AC1L2XK2

AC1Q22HP

AC1Q2G66

AC1Q3F63

AI3-19016

AIDS-006784

AIDS006784

AR-1A6363

AR-1J1632

Adermin hydrochloride

Adermine

Adermine hydrochloride

Aderomine hydrochloride

Aderoxin

Aderoxine

Alestrol

BB_NC-0050

BIDD:PXR0180

BPBio1_000646

BSPBio_000586

Becilan

Beesix

Benadon

Bonasanit

C00314

C8H11NO3

CAS-58-56-0

CBDivE_015627

CCRIS 1903

CHEBI:16709

CHEBI:30961

CHEMBL1200756

CHEMBL1364

CID104817

CID1054

CID6019

CPD0-1221

Campoviton 6

Cernevit-12

D02179

D025101

D08454

DB00165

EINECS 200-386-2

EINECS 200-603-0

EINECS 232-503-8

Godabion

Gravidox

HMS1569N08

HMS2093L07

HSDB 1212

Hexa-Betalin

Hexa-Betalin (R)

Hexa-betalin (TN)

Hexabetalin

Hexabione hydrochloride

Hexavibex

Hexermin

Hexermine

Hexobion

Hydoxin

I02-1897

I02-2297

KST-1A8556

LS-134393

LS-187072

LS-2332

MLS001074329

MLS002153915

MolPort-002-137-856

MolPort-002-319-991

MolPort-005-933-330

NCGC00016261-01

NCGC00164317-01

NCGC00180946-01

NSC 36225

NSC36225

NSC36225 (HCL)

Nestrex

Oprea1_061614

P0561

P4722_SIAL

P5669_SIGMA

P6280_SIGMA

P8666_SIGMA

P9755_SIAL

PN HCl

PYRIDOXINE HYDROCHLORIDE

PYRIDOXINE HYDROCHLORIDE, U.S.P.

Paxadon

Piridossina

Piridossina [DCIT]

Piridoxina

Piridoxina [INN-Spanish]

Prestwick0_000623

Prestwick1_000623

Prestwick2_000623

Prestwick3_000623

Prestwick_925

Pydox

Pyridipca

Pyridox

Pyridoxin

Pyridoxin hydrochloride

Pyridoxine

Pyridoxine (INN)

Pyridoxine HCl

Pyridoxine Hydrochloride

Pyridoxine Hydrochloride (B6)

Pyridoxine [INN:BAN]

Pyridoxine chloride

Pyridoxine hydrochloride

Pyridoxine hydrochloride (JP15/USP)

Pyridoxine hydrochloride [USAN:JAN]

Pyridoxine hydrogen chloride

Pyridoxine monohydrochloride

Pyridoxine, hydrochloride

Pyridoxine-HCl Microencapsulated

Pyridoxinium chloride

Pyridoxinum

Pyridoxinum [INN-Latin]

Pyridoxinum hydrochloricum

Pyridoxinum hydrochloricum (Hungarian)

Pyridoxol

Pyridoxol hydrochloride

Pyridoxol, hydrochloride

Pyridoxolum

Rodex

Rodex (R)

Rodex TD

SMP2_000230

SMR000674613

SPBio_002805

STK177324

STOCK1N-08684

Spondylonal

Tex Six T.R.

TimTec1_000657

UNII-68Y4CF58BV

UNII-KV2JZ1BI6Z

Vitamin B 6

Vitamin B6

Vitamin B6-hydrochloride

Vitamin V6

Vitamin V6 (TN)

Vitamin-?B6

Vitamin-?B6 hydrochloride

Vitaped

WLN: T6NJ B1 CQ D1Q E1Q &GH

ZINC00049154

ZINC21983293

bmse000288

c1302

component of Alestrol

nchembio.93-comp1

pyridoxine

vitamin B6

Pyridoxal

approved, nutraceutical

Phase 4, Phase 3, Phase 2

163

65-22-5, 66-72-8

1050

Synonyms:

3-HYDROXY-5-(hydroxymethyl)-2-methylisonicotinaldehyde

3-Hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde

Pyridoxal

Pyridoxaldehyde

Anti-Bacterial Agents

Phase 4, Phase 2, Phase 3

9140

Anti-Infective Agents

Phase 4, Phase 3, Phase 2, Phase 1

17220

HIV Protease Inhibitors

Phase 4, Phase 2, Phase 3

4558

Cytochrome P-450 Enzyme Inhibitors

Phase 4, Phase 2, Phase 3

3036

Raltegravir Potassium

Phase 4, Phase 3, Phase 2

288

Antimetabolites

Phase 4, Phase 3, Phase 2

9454

Cytochrome P-450 CYP3A Inhibitors

Phase 4, Phase 2, Phase 3

1421

Lamivudine, zidovudine drug combination

Phase 4, Phase 3

110

Cytochrome P-450 CYP2C9 Inhibitors

Phase 4, Phase 3, Phase 2

497

Atazanavir Sulfate

Phase 4, Phase 3, Phase 2

222

Antitubercular Agents

Phase 4, Phase 2, Phase 3

1061

Peripheral Nervous System Agents

Phase 4, Phase 3

18510

Antibiotics, Antitubercular

Phase 4, Phase 2, Phase 3

5971

Protease Inhibitors

Phase 4, Phase 2, Phase 3

4558

Immunologic Factors

Phase 4, Phase 3, Phase 2

18483

Immunosuppressive Agents

Phase 4, Phase 3, Phase 2

10422

Benzonidazole

Phase 4, Phase 3, Phase 2

Antiprotozoal Agents

Phase 4, Phase 3, Phase 2, Phase 1

1730

Adrenergic beta-Antagonists

Phase 4, Phase 3

979

Rifamycins

Phase 4

Adrenergic Antagonists

Phase 4, Phase 3

1253

Adrenergic alpha-1 Receptor Antagonists

Phase 4

405

Adrenergic alpha-Antagonists

Phase 4

586

Adrenergic Agents

Phase 4, Phase 3

4204

Anticoagulants

Phase 4

1760

Antihypertensive Agents

Phase 4, Phase 3

3618

Enalaprilat

Phase 4

112

76420-72-9

6917719

Synonyms:

(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid

(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid dihydrate

1-((2S)-2-{[(1S)-1-CARBOXY-3-PHENYLPROPYL]AMINO}PROPANOYL)-L-PROLINE

1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate

76420-72-9

AC1NUWEA

AC1OCEK7

BIDD:GT0752

C11720

C18H24N2O5.2H2O

CHEBI:116759

CHEBI:42302

CHEBI:4786

CHEBI:59877

CHEMBL1200697

CHEMBL577

CID5462501

CID6917719

CPD000466359

D03769

EAL

ENALAPRILAT INHIBITOR

Enalapril acid

Enalapril diacid

Enalaprilat

Enalaprilat (USP)

Enalaprilat anhydrous

Enalaprilate

Enalaprilatum

Enalaprilic acid

Enalprilate hydrate

HMS2051H16

HMS2089P04

LS-118903

LS-187219

MK-422

MLS000759476

MLS001424138

MolPort-005-943-792

N-[(1S)-1-Carboxy-3-phenylpropyl]-L-alanyl-L-proline

N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline

N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline--water (1/2)

NCGC00164593-01

S1657_Selleck

SAM001246684

SBB065733

SMR000466359

Vasotec I.V.

enalprilat hydrate

Nucleic Acid Synthesis Inhibitors

Phase 4, Phase 3, Phase 2

3836

Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination

Phase 4, Phase 3

130

Antiparasitic Agents

Phase 4, Phase 3, Phase 2, Phase 1

1854

Interventional clinical trials:

(show top 50) (show all 98)

id	Name	Status	NCT ID	Phase
1	Population Pharmacokinetics in Benznidazole-treated Adults With Chronic With Chagas Disease	Completed	NCT01755403	Phase 4
2	Exercise Training in Chagas Cardiomyopathy	Completed	NCT01006473	Phase 4
3	Outcomes of an Anticoagulation Clinic in an University Hospital	Completed	NCT01006486	Phase 4
4	A Randomized Trial of Carvedilol in Chronic Chagas Cardiomyopathy	Completed	NCT01557140	Phase 4
5	HIV Treatment Reinitiation in Women Who Received Anti-HIV Drugs to Prevent Mother-to-Child Transmission of HIV	Completed	NCT00442962	Phase 4
6	Immediate Versus Deferred Start of Anti-HIV Therapy in HIV-Infected Adults Being Treated for Tuberculosis	Completed	NCT00108862	Phase 4
7	Pharmacokinetics of the Tablet Formulation of Lopinavir/r as Standard and Increased Dosage During Pregnancy	Completed	NCT00605098	Phase 4
8	An Evaluation of the Pharmacological Interaction of Lopinavir/r and Rifampin	Completed	NCT00771498	Phase 4
9	Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings	Completed	NCT00084136	Phase 4
10	Clinical Assessment, Neuroimaging and Immunomarkers in Chagas Disease Study (CLINICS)	Recruiting	NCT01650792	Phase 4
11	Reveal Chagas: Clinical Evidence of the Implantable Cardiac Monitor in Patients With Chagas Disease	Recruiting	NCT01539161	Phase 4
12	Optimization of PCR Technique to Assess Parasitological Response for Patients With Chronic Chagas Disease	Active, not recruiting	NCT01678599	Phase 4
13	Population Pharmacokinetics Study of Benznidazole in Children With Chagas'Disease	Active, not recruiting	NCT01549236	Phase 4
14	REMEMBER: Reducing Early Mortality & Morbidity by Empiric Tuberculosis (TB) Treatment	Active, not recruiting	NCT01380080	Phase 4
15	A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure	Active, not recruiting	NCT01641367	Phase 4
16	Etiologic Treatment With Benznidazole in Adult Patients With Chronic Chagas Disease. A Randomized Clinical Trial	Completed	NCT02386358	Phase 3
17	Cardiac Rehabilitation in Chagas Heart Failure	Completed	NCT02516293	Phase 2, Phase 3
18	Chagas Cardiomyopathy Bisoprolol Intervention Study: Charity	Completed	NCT00323973	Phase 3
19	Amprenavir/Ritonavir or Saquinavir/Ritonavir in HIV-Infected Subjects Following Failure With Kaletra as Their Second Protease Inhibitor	Completed	NCT00038519	Phase 2, Phase 3
20	A Study to Compare Two Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Previously Received Anti-HIV Treatment	Completed	NCT00004581	Phase 3
21	A Phase III Study Comparing Two Different Anti-HIV Drug Combinations in HIV-Positive Patients Without Previous Anti-HIV Drug Therapy	Completed	NCT00004583	Phase 3
22	Safety and Efficacy of COBI-boosted Atazanavir Versus Ritonavir-boosted Atazanavir Each Administered With Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults	Completed	NCT01108510	Phase 3
23	Rollover Trial Safety and Tolerability of Combination Tipranavir and Ritonavir Use in HIV 1 Infected Subjects	Completed	NCT00146328	Phase 2, Phase 3
24	Preventing Sexual Transmission of HIV With Anti-HIV Drugs	Completed	NCT00074581	Phase 3
25	Evaluating the Effectiveness of the Quadrivalent Human Papillomavirus (HPV) Vaccine at Preventing Anal HPV Infection in HIV-Infected Men and Women	Completed	NCT01461096	Phase 3
26	Study of Options for Second-Line Effective Combination Therapy (SELECT)	Completed	NCT01352715	Phase 3
27	Prospective Study of a Pediatric Nifurtimox Formulation for Chagas' Disease	Recruiting	NCT02625974	Phase 3
28	Selenium Treatment and Chagasic Cardiopathy (STCC)	Recruiting	NCT00875173	Phase 3
29	BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' Disease	Recruiting	NCT00123916	Phase 3
30	CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY)	Recruiting	NCT02369978	Phase 2, Phase 3
31	Physical Exercise Program in Chronic Chagas Heart Disease	Recruiting	NCT02517632	Phase 3
32	Low Antimonial Dosage in American Mucosal Leishmaniasis	Recruiting	NCT01301937	Phase 2, Phase 3
33	Three Chemo Regimens as an Adjunct to ART for Treatment of Advanced AIDS-KS	Recruiting	NCT01435018	Phase 3
34	Study of Immunogenicity, Reactogenicity and Safety of the Combined Measles, Mumps and Rubella Vaccine Produced by Bio-Manguinhos/Fiocruz in Children 12-15 Months of Age, Followed by Tetraviral Vaccine in Children 15-18 Months.	Recruiting	NCT01991899	Phase 3
35	Open-label Safety Study of E/C/F/TAF (Genvoya®) in HIV-1 Positive Patients With Mild to Moderate Renal Impairment	Active, not recruiting	NCT01818596	Phase 3
36	Can Valacyclovir Delay the Need for Initiation of Human Immunodeficiency Virus (HIV) Treatment in HIV-infected Individuals?	Active, not recruiting	NCT00860977	Phase 3
37	Evaluating the Safety and Effectiveness of Short-Course Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-Infected Individuals With Latent Tuberculosis Infection	Active, not recruiting	NCT01404312	Phase 3
38	Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcoma	Active, not recruiting	NCT01352117	Phase 3
39	Switching From a TDF-Containing Combination Regimen to a TAF-Containing Fixed Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Positive Participants	Active, not recruiting	NCT01815736	Phase 3
40	Comparison of Standard and Alternative Antimonial Dosage in Patients With American Cutaneous Leishmaniasis	Active, not recruiting	NCT01301924	Phase 2, Phase 3
41	Shortening Treatment by Advancing Novel Drugs	Suspended	NCT02342886	Phase 3
42	Cell Therapy in Chagas Cardiomyopathy	Terminated	NCT00349271	Phase 3
43	Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis	Terminated	NCT00330148	Phase 3
44	A Study of the Use of Oral Posaconazole (POS) in the Treatment of Asymptomatic Chronic Chagas Disease (P05267)	Completed	NCT01377480	Phase 2
45	Clinical Trial For The Treatment Of Chronic Chagas Disease With Posaconazole And Benznidazole	Completed	NCT01162967	Phase 2
46	Safety and Efficacy Study of Stem Cell Transplantation to Treat Dilated Cardiomyopathy	Completed	NCT00629018	Phase 2
47	Safety of and Immune Response to the Human Papillomavirus (HPV) Vaccine in HIV-Infected Women	Completed	NCT00604175	Phase 2
48	Safety and Effectiveness of Lamivudine When Given Once a Day Versus Twice a Day in Combination With Other Anti-HIV Drugs in HIV-Infected Adults Who Have Never Received Anti-HIV Drugs	Completed	NCT00004852	Phase 2
49	Proof-of-Concept Study of E1224 to Treat Adult Patients With Chagas Disease	Recruiting	NCT01489228	Phase 2
50	Study to Evaluate Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chagas Disease	Recruiting	NCT02498782	Phase 2

Search NIH Clinical Center for Chagas Disease

Genetic Tests for Chagas Disease

Anatomical Context for Chagas Disease

Sources:
³³MalaCards
See all MalaCards sources

MalaCards organs/tissues related to Chagas Disease:

³³

Heart, Testes, Eye, Liver, Colon, Lymph node, Breast

Animal Models for Chagas Disease or affiliated genes

Sources:
³⁸MGI
See all MalaCards sources

MGI Mouse Phenotypes related to Chagas Disease:

³⁸ (show all 22)

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	adipose tissue	MP:0005375	9.0	ADRB1, IL6, NOS2, TGFB1, TLR2, TLR4
2	craniofacial	MP:0005382	8.9	CYP51A1, IFNG, IL10, IL12B, NOS2, TGFB1
3	reproductive system	MP:0005389	8.6	CCR5, IFNG, IL10, IL2, IL6, NOS2
4	liver/biliary system	MP:0005370	8.5	CCR5, IFNG, IL10, IL2, IL6, NOS2
5	respiratory system	MP:0005388	8.5	IFNG, IL10, IL12B, IL2, IL6, NOS2
6	endocrine/exocrine gland	MP:0005379	8.3	ADRB1, CD4, IFNG, IL10, IL2, IL6
7	no phenotypic analysis	MP:0003012	8.1	ADRB1, CCR5, CD4, CYP51A1, IFNG, IL10
8	vision/eye	MP:0005391	8.1	CCR5, GSR, IFNG, IL10, IL6, NOS2
9	behavior/neurological	MP:0005386	7.9	CCR5, IFNG, IL10, IL2, IL6, NOS2
10	tumorigenesis	MP:0002006	7.9	CCR5, IFNG, IL10, IL12B, IL1B, IL2
11	integument	MP:0010771	7.9	CD4, IFNG, IL10, IL1B, IL6, NOS2
12	cellular	MP:0005384	7.8	CCR5, CD4, IFNG, IL10, IL2, IL6
13	skeleton	MP:0005390	7.5	ADRB1, CYP51A1, IFNG, IL10, IL12B, IL1B
14	muscle	MP:0005369	7.4	ADRB1, CCR5, CYP51A1, IFNG, IL10, IL6
15	nervous system	MP:0003631	7.4	CCR5, CD4, IFNG, IL10, IL1B, IL6
16	digestive/alimentary	MP:0005381	7.2	CCR5, CD4, CYP51A1, IFNG, IL10, IL12B
17	growth/size/body region	MP:0005378	7.0	ADRB1, CD4, CYP51A1, IFNG, IL10, IL2
18	cardiovascular system	MP:0005385	6.9	ADRB1, CCR5, CYP51A1, GSR, IFNG, IL10
19	homeostasis/metabolism	MP:0005376	6.6	ADRB1, CCR5, CD4, CYP51A1, IFNG, IL10
20	hematopoietic system	MP:0005397	6.2	CCR5, CD4, IFNG, IL10, IL12B, IL1B
21	mortality/aging	MP:0010768	6.0	ADRB1, CCR5, CD4, CYP51A1, IFNG, IL10
22	immune system	MP:0005387	5.9	CCL2, CCR5, CD4, CYP51A1, IFNG, IL10

Publications for Chagas Disease

Sources:
⁵⁴PubMed
See all MalaCards sources

Articles related to Chagas Disease:

(show top 50) (show all 744)

id	Title	Authors	Year
1	Serological Diagnosis of Chronic Chagas Disease: Is It Time for a Change? (27053668)	Abras A.... MuA+oz C.	2016
2	Putting Chagas disease on the US radar screen. (25803331)	Kuehn B.M.	2015
3	Chagas disease and transfusion medicine: a perspective from non-endemic countries. (26513769)	Angheben A.... Aprili G.	2015
4	Long-term follow-up of a patient since the acute phase of Chagas disease (South American trypanosomiasis): further treatment and cure of the infection. (26516979)	Dias J.C.... NA^brega G.C.	2015
5	Community-based sampling methods for surveillance of the Chagas disease vector, Triatoma dimidiata (Hemiptera: Reduviidae: Triatominae). (25276934)	Weeks E.N.... Cameron M.M.	2014
6	Improvement of the functional capacity is associated with BDNF and autonomic modulation in Chagas disease. (23232458)	Lima M.M.... Ribeiro A.L.	2013
7	Chagas disease is a consideration in latino patients. (24364628)	Zammarchi L.... Munoz J.	2013
8	Pediatric Chagas Disease in Europe: 45 Cases from Spain and Switzerland. (24153010)	Guerineau L.R.... Jackson Y.	2013
9	Another disappointing result with implantable cardioverter-defibrillator therapy in patients with Chagas disease. (23585252)	Rassi A.... Rassi A.	2013
10	21-Hydroxylase gene mutant allele CYP21A215 strongly linked to the resistant HLA haplotype B14:02-DRB1*01:02 in chronic Chagas disease. (23376085)	del Puerto F.... Hirayama K.	2013
11	Cardiomyocyte dysfunction during the chronic phase of Chagas disease. (23579807)	Roman-Campos D.... Cruz J.S.	2013
12	The improbable transmission of Trypanosoma cruzi to human: the missing link in the dynamics and control of Chagas disease. (24244766)	Nouvellet P.... GourbiA"re S.	2013
13	South-south cooperation for Chagas disease. (23911378)	Salvatella R.... Espinal M.	2013
14	Elevated serum levels of macrophage migration inhibitory factor are associated with progressive chronic cardiomyopathy in patients with Chagas disease. (23451183)	Cutrullis R.A.... Corral R.S.	2013
15	Anatomy of the spermatophore in triatomines (Hemiptera, Reduviidae, Triatominae) and its applications to the study of Chagas disease vector biology. (23958911)	Pereira-LourenAso A.S.... Freitas S.P.	2013
16	Laparoscopic Heller myotomy and fundoplication in patients with Chagas' disease achalasia and massively dilated esophagus. (23317615)	Pantanali C.A.... Patti M.G.	2013
17	Pharmacokinetics of hydroxymethylnitrofurazone, a promising new prodrug for chagas' disease treatment. (24080661)	Serafim E.O.... Chung M.C.	2013
18	Combined measurement of N-terminal pro-B-type natriuretic peptide and highly sensitive cardiac troponin T for diagnosis and monitoring of heart injury in chronic Chagas' disease. (23810852)	Munoz Saravia S.G.... Schimke I.	2013
19	Evaluating Chagas disease progression and cure through blood-derived biomarkers: a systematic review. (24053276)	Requena-MAcndez A.... MuA+oz J.	2013
20	Intensified surveillance and insecticide-based control of the Chagas disease vector Triatoma infestans in the Argentinean Chaco. (23593525)	Gurevitz J.M.... GA1rtler R.E.	2013
21	Heart failure survival score in patients with Chagas disease: correlation with functional variables. (22513344)	Ritt L.E.... Lopes R.D.	2012
22	Insights into the clinical and functional significance of cardiac autonomic dysfunction in Chagas disease. (22535000)	Junqueira Jr L.F.	2012
23	Triatomines in dwellings and outbuildings in an endemic area of Chagas disease in northeastern Brazil. (23295872)	Lima A.F.... Melo C.M.	2012
24	Is it safe to use a liver graft from a Chagas disease-seropositive donor in a human immunodeficiency virus-positive recipient? A case report addressing a novel challenge in liver transplantation. (22508549)	Goldaracena N.... McCormack L.	2012
25	Foxp3+CD25(high) CD4+ regulatory T cells from indeterminate patients with Chagas disease can suppress the effector cells and cytokines and reveal altered correlations with disease severity. (22672991)	de AraA_jo F.F.... Gomes J.A.	2012
26	Chagas disease in the immunosuppressed host. (22614520)	Bern C.	2012
27	Agrochemicals against malaria, sleeping sickness, leishmaniasis and Chagas disease. (23145187)	Witschel M.... Brun R.	2012
28	Different infective forms trigger distinct immune response in experimental Chagas disease. (22412949)	Vieira P.M.... Carneiro C.M.	2012
29	Barriers to Testing and Treatment for Chagas Disease among Latino Immigrants in Georgia. (23326646)	Minneman R.M.... Leon J.S.	2012
30	Chagas disease in European countries: the challenge of a surveillance system. (21944556)	Basile L.... Albajar-Vinas P.	2011
31	Antitrypanosomal therapy for chronic Chagas' disease. (21991908)	Garcia-Bournissen F.... Altcheh J.	2011
32	Mitochondrial dysfunction in Trypanosoma cruzi: the role of Serratia marcescens prodigiosin in the alternative treatment of Chagas disease. (21548954)	Genes C.... Triana O.	2011
33	Immunoneuroendocrine alterations in patients with progressive forms of chronic Chagas disease. (21496931)	PAcrez A.R.... Bottasso O.	2011
34	Chagas disease among the Latin American adult population attending in a primary care center in Barcelona, Spain. (21572511)	Roca C.... GascA^n J.	2011
35	Megacolon from Chagas disease in an ancient Texan. Diagnosis: Chagas disease causing mega-disease, in this case megacolon. (21640110)	Barth E.... Kundrotas L.	2011
36	Screening and treatment of chagas disease in organ transplant recipients in the United States: recommendations from the chagas in transplant working group. (21401868)	Chin-Hong P.V.... Ison M.G.	2011
37	The use of IgG antibodies in conventional and non-conventional immunodiagnostic tests for early prognosis after treatment of Chagas disease. (21620855)	Wendling A.P.... Martins-Filho O.A.	2011
38	2-DE-based proteomic investigation of the saliva of the Amazonian triatomine vectors of Chagas disease: Rhodnius brethesi and Rhodnius robustus. (21362504)	Costa C.M.... Charneau S.	2011
39	Selective decrease of components of the creatine kinase system and ATP synthase complex in chronic Chagas disease cardiomyopathy. (21738806)	Teixeira P.C.... Cunha-Neto E.	2011
40	Surveillance of Chagas disease in pregnant women in Madrid, Spain, from 2008 to 2010. (21958533)	Flores-Chavez M.D.... Cuadros J.	2011
41	The chemistry and biology of trypanosomal trans-sialidases: virulence factors in Chagas disease and sleeping sickness. (21956798)	Schauer R.... Kamerling J.P.	2011
42	Differential expression of Trypanosoma cruzi I associated with clinical forms of Chagas disease: overexpression of oxidative stress proteins in acute patient isolate. (21642025)	DA-az M.L.... GonzA!lez C.I.	2011
43	Role of the IFNG +874T/A polymorphism in Chagas disease in a Colombian population. (20359550)	Torres O.A.... MartA-n J.	2010
44	Targeting the polyamine biosynthetic enzymes: a promising approach to therapy of African sleeping sickness, Chagas' disease, and leishmaniasis. (17610127)	Heby O.... Rentala M.	2007
45	Does the C-type natriuretic peptide have prognostic value in chagas disease and other dilated cardiomyopathies? (17204908)	Heringer-Walther S.... Walther T.	2006
46	Chagasic cardiomyopathy is independently associated with ischemic stroke in Chagas disease. (15845889)	Carod-Artal F.J.... Nunes L.G.	2005
47	American trypanosomiasis (Chagas' disease): an unrecognised cause of stroke. (12640079)	Carod-Artal F.J.... Horan T.A.	2003
48	Analysis of the T-cell receptor beta-chain variable-region (Vbeta) repertoire in chronic human Chagas' disease. (12366778)	FernA!ndez-Mestre M.T.... Layrisse Z.	2002
49	Response of the lower esophageal sphincter to pentagastrin on patients with megaesophagus secondary to Chagas' disease. (2517711)	Moraes-Filho J.P.... Bettarello A.	1989
50	(23205684)

Genes related to Chagas Disease

Sources:
²⁰GeneCards, ¹²DISEASES, ⁴⁷Novoseek
See all MalaCards sources

Genes related to Chagas Disease:

(show all 22)

- Elite gene

- Cancer Census gene in COSMIC

id	Symbol	Description	Score	Implication	PubmedIds
1	TNF	Tumor Necrosis Factor	33.87	DISEASES inferred ¹² GeneCards inferred via : Publications, Pathways & Interactions (show sections)
2	IL10	Interleukin 10	33.78	DISEASES inferred ¹² GeneCards inferred via : Publications, Pathways & Interactions (show sections)
3	IFNG	Interferon, Gamma	33.16	DISEASES inferred ¹² GeneCards inferred via : Publications, Pathways & Interactions (show sections)
4	TLR2	Toll Like Receptor 2	32.31	DISEASES inferred ¹² GeneCards inferred via : Publications, Pathways & Interactions (show sections)
5	CCL2	C-C Motif Chemokine Ligand 2	32.05	DISEASES inferred ¹² GeneCards inferred via : Publications, Pathways & Interactions (show sections)
6	IL2	Interleukin 2	31.78	DISEASES inferred ¹² GeneCards inferred via : Publications, Pathways & Interactions (show sections)
7	TGFB1	Transforming Growth Factor Beta 1	31.65	DISEASES inferred ¹² GeneCards inferred via : Publications, Pathways & Interactions (show sections)
8	IL6	Interleukin 6	31.34	DISEASES inferred ¹² GeneCards inferred via : Publications, Pathways & Interactions (show sections)
9	IL1B	Interleukin 1 Beta	31.22	DISEASES inferred ¹² GeneCards inferred via : Publications, Pathways & Interactions (show sections)
10	TLR4	Toll Like Receptor 4	31.09	DISEASES inferred ¹² GeneCards inferred via : Publications, Pathways & Interactions (show sections)
11	CYP51A1	Cytochrome P450 Family 51 Subfamily A Member 1	28.88	DISEASES inferred ¹² Novoseek inferred ⁴⁷ GeneCards inferred via : Publications (show sections)	16321980, 20429511
12	NPPB	Natriuretic Peptide B	27.29	DISEASES inferred ¹² Novoseek inferred ⁴⁷ GeneCards inferred via : Publications (show sections)	15761636, 12241721, 17057935 more 20142028, 15710733, 15034825, 12892979, 16023747, 20090473, 12737906
13	GSR	Glutathione Reductase	27.08	DISEASES inferred ¹² Novoseek inferred ⁴⁷ GeneCards inferred via : Publications (show sections)	10571254
14	ADRB1	Adrenoceptor Beta 1	26.84	DISEASES inferred ¹² Novoseek inferred ⁴⁷ GeneCards inferred via : Publications (show sections)	19823676
15	IL12B	Interleukin 12B	26.53	GeneCards inferred via : Publications, Pathways & Interactions (show sections)
16	NOS2	Nitric Oxide Synthase 2	26.53	GeneCards inferred via : Publications, Pathways & Interactions (show sections)
17	CCR5	C-C Motif Chemokine Receptor 5 (Gene/Pseudogene)	26.38	DISEASES inferred ¹² Novoseek inferred ⁴⁷ GeneCards inferred via : Publications (show sections)	16299288, 11703822
18	NTRK1	Neurotrophic Receptor Tyrosine Kinase 1	26.33	DISEASES inferred ¹² Novoseek inferred ⁴⁷ GeneCards inferred via : Publications (show sections)	15447671, 18832578, 18410251 more 18005706
19	CD4	CD4 Molecule	26.27	DISEASES inferred ¹² Novoseek inferred ⁴⁷ GeneCards inferred via : Publications (show sections)	1427979
20	TCFL5	Transcription Factor Like 5	17.02	GeneCards inferred via : Publications, Proteins (show sections)
21	CALR	Calreticulin	15.43	DISEASES inferred ¹² Novoseek inferred ⁴⁷ GeneCards inferred via : Pathways & Interactions (show sections)	19108895, 15128045
22	AMD1	Adenosylmethionine Decarboxylase 1	15.34	DISEASES inferred ¹² Novoseek inferred ⁴⁷ GeneCards inferred via : Publications (show sections)	9677309

Variations for Chagas Disease

Expression for genes affiliated with Chagas Disease

Sources:
¹⁷Gene Expression Omnibus DataSets
See all MalaCards sources

Search GEO for disease gene expression data for Chagas Disease.

Pathways for genes affiliated with Chagas Disease

Sources:
⁵²PathCards, ⁵⁵QIAGEN, ⁵⁶R&D Systems, ⁶²Thomson Reuters, ⁵⁷Reactome, ³¹KEGG, ³⁹NCBI BioSystems Database
See all MalaCards sources

Pathways related to Chagas Disease according to KEGG:

³¹

id	Name	KEGG Source Accession
1	Chagas disease (American trypanosomiasis)	hsa05142

Pathways related to Chagas Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 66)

id	Super pathways	Score	Top Affiliating Genes
1	OX40 Pathway⁵⁵	9.9	IFNG, IL10, IL2
2	LDL Oxidation in Atherogenesis⁵⁵	9.9	CCL2, IL1B, TNF
3	IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types⁵⁶	9.8	IL1B, IL6, TGFB1
4	Transcription_Role of VDR in regulation of genes involved in osteoporosis⁶²	9.6	IFNG, IL1B, IL6, TNF
5	IL-15 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types⁵⁶ Show member pathways IL-2 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types⁵⁶	9.5	IFNG, IL10, IL2, TGFB1, TNF
6	Cytokine production by Th17 cells in CF⁶² Show member pathways Cytokine production by Th17 cells in CF (Mouse model)⁶² Transfer of LPS from LBP carrier to CD14⁵⁷	9.4	IL12B, IL6, TGFB1, TLR4
7	AGE-RAGE signaling pathway in diabetic complications³¹	9.4	CCL2, IL1B, IL6, TGFB1, TNF
8	IL-10 Pathway⁵⁵	9.4	IL10, IL1B, IL6, TLR4, TNF
9	Th2 Differentiation Pathway⁵⁶	9.4	CD4, IFNG, IL10, IL2
10	IL12 signaling mediated by STAT4³⁹	9.3	CD4, IFNG, IL2, TGFB1
11	Jak-STAT signaling pathway³¹ Show member pathways Type III interferon signaling³⁹ Interleukin-19, 20, 22, 24⁵⁷ IL-7 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types⁵⁶ B-Cell Development⁵⁵	9.3	IFNG, IL10, IL12B, IL2, IL6
12	Jak/STAT Signaling Pathway⁵⁶	9.3	IFNG, IL10, IL12B, IL2, IL6
13	Hematopoietic cell lineage³¹	9.3	CD4, IL1B, IL6, TNF
14	Immune response_MIF-mediated glucocorticoid regulation⁶²	9.3	IFNG, IL2, IL6, NOS2, TNF
15	Salmonella infection (KEGG)³¹ Show member pathways Salmonella infection³¹	9.2	IFNG, IL1B, IL6, NOS2, TLR4
16	Selenium Pathway³⁹ Show member pathways thioredoxin pathway³⁹	9.1	CCL2, GSR, IFNG, IL1B, IL6, TNF
17	African trypanosomiasis³¹	9.1	IFNG, IL10, IL12B, IL1B, IL6, TNF
18	Proteoglycans in cancer³¹	9.1	IL12B, IL6, TGFB1, TLR2, TLR4, TNF
19	Legionellosis³¹	9.0	IL12B, IL1B, IL6, TLR2, TLR4, TNF
20	Toll Comparative Pathway⁵⁵ Show member pathways IL-1 Pathway⁵⁵ Immune response MIF in innate immunity response⁶² iNOS Signaling⁵⁵ TLR-TRIF Pathway⁵⁵	9.0	IFNG, IL1B, IL6, NOS2, TLR4, TNF
21	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers⁵⁶	9.0	CD4, IFNG, IL10, IL2, IL6, TNF
22	Innate Lymphoid Cell Differentiation Pathways⁵⁶	9.0	CD4, IFNG, IL10, IL1B, IL2, TNF
23	NF-KappaB Family Pathway⁵⁵ Show member pathways NF-KappaB (p50-p65) Pathway⁵⁵	9.0	IL1B, IL2, IL6, TGFB1, TLR2, TLR4
24	Immune response IFN alpha/beta signaling pathway⁶² Show member pathways Interferon alpha/beta signaling⁵⁷ Cytokine Network⁵⁵ Regulation of IFNA signaling⁵⁷	8.9	IFNG, IL10, IL12B, IL1B, IL2, IL6
25	IgA-Producing B Cells in the Intestine⁵⁶	8.9	IL10, IL6, NOS2, TGFB1, TLR2, TLR4
26	Colorectal Cancer Metastasis⁵⁵	8.8	IFNG, IL6, NOS2, TGFB1, TLR2, TLR4
27	Bacterial infections in CF airways⁶² Show member pathways Immune response TLR signaling pathways⁶² Immune response Bacterial infections in normal airways⁶² IL-1 beta-dependent CFTR expression⁶²	8.8	IFNG, IL1B, IL6, NOS2, TLR2, TLR4
28	Rheumatoid arthritis³¹	8.8	CCL2, IFNG, IL1B, IL6, TGFB1, TLR2
29	Pertussis³¹	8.7	IL10, IL12B, IL1B, IL6, NOS2, TLR4
30	Malaria³¹	8.6	CCL2, IFNG, IL10, IL1B, IL6, TGFB1
31	Dendritic Cells Developmental Lineage Pathway⁵⁶	8.5	CD4, IFNG, IL10, IL1B, IL2, IL6
32	MSP-RON Signaling⁵⁵	8.5	CCL2, IFNG, IL12B, IL1B, NOS2, TLR2
33	Influenza A³¹ Show member pathways Herpes simplex infection³¹ Measles³¹	8.4	CCL2, IFNG, IL12B, IL1B, IL2, IL6
34	Spinal Cord Injury³⁹	8.4	CCL2, IFNG, IL1B, IL2, IL6, NOS2
35	Th17 Differentiation Pathway⁵⁶ Show member pathways IL-21 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types⁵⁶	8.3	CD4, IFNG, IL12B, IL1B, IL6, TGFB1
36	IL12-mediated signaling events³⁹ Show member pathways Immune response IL-12-induced IFN-gamma production⁶²	8.2	CCR5, CD4, IFNG, IL12B, IL1B, IL2
37	Cytokines and Inflammatory Response³⁹	8.2	CD4, IFNG, IL10, IL12B, IL1B, IL2
38	B cell receptor signaling pathway (KEGG)³¹ Show member pathways B cell receptor signaling pathway³¹ T cell receptor signaling pathway³¹ TCR Signaling Pathway³⁹ BCR signaling pathway³⁹	8.1	CCR5, CD4, IFNG, IL10, IL1B, IL2
39	Amoebiasis³¹	8.1	IFNG, IL10, IL12B, IL1B, IL6, NOS2
40	Tuberculosis³¹	8.1	IFNG, IL10, IL12B, IL1B, IL6, NOS2
41	Toxoplasmosis³¹ Show member pathways Leishmaniasis³¹	7.9	CCR5, IFNG, IL10, IL12B, IL1B, NOS2
42	Immune response IL-23 signaling pathway⁶² Show member pathways Development PDGF signaling via STATs and NF-kB⁶² Immune response IL-10 signaling pathway⁶² Development Angiopoietin - Tie2 signaling⁶² Angiopoietin-TIE2 Signaling⁵⁵ Angiopoietin receptor Tie2-mediated signaling³⁹ IL23-mediated signaling events³⁹	7.8	CCL2, CD4, IFNG, IL10, IL12B, IL1B
43	Allograft rejection³⁹ ³¹ Show member pathways Antigen processing and presentation³¹ Viral myocarditis³¹ Intestinal immune network for IgA production³¹ CTL Mediated Apoptosis⁵⁵ THC Differentiation Pathway⁵⁵ Allograft Rejection³⁹ Asthma³¹ Autoimmune thyroid disease³¹ Type I diabetes mellitus³¹ Graft-versus-host disease³¹ Inflammatory bowel disease (IBD)³¹	7.7	CD4, IFNG, IL10, IL12B, IL1B, IL2
44	IL27-mediated signaling events³⁹ Show member pathways Th1 Differentiation Pathway⁵⁶ IL-12 Family Signaling Pathways⁵⁶	7.7	CD4, IFNG, IL10, IL12B, IL1B, IL2
45	Toll-like receptor signaling pathway³⁹ ³¹ Show member pathways Chagas disease (American trypanosomiasis)³¹ Regulation of toll-like receptor signaling pathway³⁹ Hepatitis B³¹	7.7	CCL2, IFNG, IL10, IL12B, IL1B, IL2
46	TGF-Beta Pathway⁵⁵ Show member pathways JNK Pathway⁵⁵ MAPK Family Pathway⁵⁵ JAK-STAT Pathway⁵⁵ Regulation of eIF4 and p70S6K⁵⁵ SOCS Pathway⁵⁵	7.5	CCL2, CD4, IFNG, IL10, IL12B, IL1B
47	PAK Pathway⁵⁵ Show member pathways Epithelial Adherens Junctions⁵⁵ Antioxidant Action of Vitamin-C⁵⁵	7.3	CCL2, CCR5, CD4, IL10, IL12B, IL1B
48	ERK Signaling⁵⁵ Show member pathways Molecular Mechanisms of Cancer⁵⁵ Rho Family GTPases⁵⁵ ILK Signaling⁵⁵ MAPK Signaling⁵⁵	6.9	CCL2, CCR5, CD4, IL10, IL12B, IL1B
49	Akt Signaling⁵⁵ Show member pathways Tec Kinases Signaling⁵⁵ p38 Signaling⁵⁵	6.8	CCL2, CCR5, CD4, IL10, IL12B, IL1B
50	PEDF Induced Signaling⁵⁵ Show member pathways IL-6 Pathway⁵⁵ Endothelin-1 Signaling Pathway⁵⁵ Cytokine-cytokine receptor interaction³¹ STAT3 Pathway⁵⁵ Glucocorticoid Receptor Signaling⁵⁵ all-trans-Retinoic Acid Signaling in Brain⁵⁵ NFAT Signaling and Lymphocyte Interactions⁵⁵ MIF Regulation of Innate Immune Cells⁵⁵ MIF Mediated Glucocorticoid Regulation⁵⁵ RAR-Gamma-RXR-Alpha Degradation⁵⁵ PGC1Alpha Pathway⁵⁵	6.5	CCL2, CCR5, CD4, IFNG, IL10, IL12B

GO Terms for genes affiliated with Chagas Disease

Sources:
¹⁸Gene Ontology
See all MalaCards sources

Cellular components related to Chagas Disease according to GeneCards Suite gene sharing:

id	Name	GO ID	Score	Top Affiliating Genes
1	external side of plasma membrane	GO:0009897	9.7	GSR, IL6, TLR4

Biological processes related to Chagas Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 89)

id	Name	GO ID	Score	Top Affiliating Genes
1	neutrophil apoptotic process	GO:0001781	10.8	IFNG, IL6
2	sequestering of triglyceride	GO:0030730	10.8	IL1B, TNF
3	positive regulation of calcidiol 1-monooxygenase activity	GO:0060559	10.6	IFNG, IL1B, TNF
4	positive regulation of membrane protein ectodomain proteolysis	GO:0051044	10.6	IFNG, IL1B, TNF
5	positive regulation of chemokine biosynthetic process	GO:0045080	10.6	IFNG, IL1B, TNF
6	positive regulation of chemokine production	GO:0032722	10.6	TLR2, TLR4, TNF
7	positive regulation of NF-kappaB import into nucleus	GO:0042346	10.5	IL1B, TLR4, TNF
8	positive regulation of nitric oxide biosynthetic process	GO:0045429	10.5	IL1B, IL6, TNF
9	positive regulation of nitric-oxide synthase biosynthetic process	GO:0051770	10.5	CCL2, TLR2, TLR4
10	positive regulation of tumor necrosis factor production	GO:0032760	10.5	IFNG, TLR2, TLR4
11	negative regulation of interleukin-6 production	GO:0032715	10.5	IL10, TLR4, TNF
12	protein import into nucleus, translocation	GO:0000060	10.4	IFNG, TGFB1, TNF
13	negative regulation of fat cell differentiation	GO:0045599	10.4	IL6, TGFB1, TNF
14	positive regulation of interleukin-17 production	GO:0032740	10.4	IL12B, IL2, TGFB1
15	positive regulation of T cell proliferation	GO:0042102	10.4	IFNG, IL12B, IL2
16	positive regulation of MHC class II biosynthetic process	GO:0045348	10.3	IFNG, IL10, TLR4
17	positive regulation of osteoclast differentiation	GO:0045672	10.2	IFNG, IL12B, TNF
18	negative regulation of growth of symbiont in host	GO:0044130	10.2	IFNG, IL10, IL12B, TNF
19	defense response to protozoan	GO:0042832	10.2	IFNG, IL10, IL12B, IL6
20	positive regulation of sequence-specific DNA binding transcription factor activity	GO:0051091	10.2	IL10, IL1B, IL6, TNF
21	negative regulation of interleukin-17 production	GO:0032700	10.2	IFNG, IL12B, TGFB1, TLR4
22	positive regulation of interleukin-12 production	GO:0032735	10.1	IFNG, IL12B, TLR2, TLR4
23	cellular response to dexamethasone stimulus	GO:0071549	10.1	CCL2, IL6, TGFB1
24	positive regulation of cell adhesion	GO:0045785	10.1	CCL2, IFNG, IL12B, TNF
25	extrinsic apoptotic signaling pathway	GO:0097191	10.1	IFNG, TGFB1, TLR4, TNF
26	response to glucocorticoid	GO:0051384	10.0	CCL2, IL10, IL1B, IL6, TNF
27	negative regulation of gene expression	GO:0010629	10.0	IFNG, IL1B, TGFB1, TNF
28	positive regulation of interleukin-6 production	GO:0032755	9.9	IL1B, IL6, TLR4, TNF
29	response to bacterium	GO:0009617	9.8	CCL2, IL6, NOS2, TLR4
30	aging	GO:0007568	9.8	CCL2, IL10, IL1B, IL6, TGFB1
31	cytokine-mediated signaling pathway	GO:0019221	9.8	CCL2, IFNG, IL12B, IL1B, IL6
32	positive regulation of interferon-gamma production	GO:0032729	9.8	IL12B, IL1B, IL2, TLR4, TNF
33	lipopolysaccharide-mediated signaling pathway	GO:0031663	9.8	CCL2, IL1B, TGFB1, TLR2, TLR4
34	positive regulation of transcription, DNA-templated	GO:0045893	9.7	IFNG, IL10, IL1B, IL6, TGFB1, TNF
35	positive regulation of NF-kappaB transcription factor activity	GO:0051092	9.7	IL1B, IL6, NTRK1, TNF
36	positive regulation of inflammatory response	GO:0050729	9.7	CCL2, IL12B, IL2, TLR2, TLR4
37	response to vitamin D	GO:0033280	9.7	CD4, IL1B, TGFB1
38	positive regulation of protein phosphorylation	GO:0001934	9.6	IL1B, IL2, NTRK1, TGFB1, TNF
39	response to heat	GO:0009408	9.5	CCL2, IL1B, IL6
40	cell-cell signaling	GO:0007267	9.4	ADRB1, CCR5, IL10, IL1B, IL2
41	defense response to bacterium	GO:0042742	9.4	IFNG, IL10, NOS2, TLR4, TNF
42	T cell activation	GO:0042110	9.4	CD4, IL6, TGFB1
43	MAPK cascade	GO:0000165	9.4	CCL2, CCR5, IL1B, IL2, TGFB1, TNF
44	inflammatory response	GO:0006954	9.4	IL10, IL1B, IL6, NOS2, TGFB1, TNF
45	positive regulation of gene expression	GO:0010628	9.3	IFNG, IL1B, IL6, TGFB1, TLR4
46	defense response to Gram-negative bacterium	GO:0050829	9.2	CD4, IL12B, IL6, NOS2, TLR4
47	response to drug	GO:0042493	9.0	CCL2, IFNG, IL10, IL1B, IL6, NTRK1
48	positive regulation of transcription from RNA polymerase II promoter	GO:0045944	8.8	IFNG, IL10, IL1B, IL2, IL6, TGFB1
49	cellular response to lipopolysaccharide	GO:0071222	8.7	CCL2, IFNG, IL12B, IL1B, IL6, NOS2
50	immune response	GO:0006955	8.3	CCL2, CD4, IFNG, IL10, IL1B, IL2