Chagas Disease malady

MedlinePlus:³⁴ Chagas disease is caused by a parasite. it is common in latin america but not in the united states. infected blood-sucking bugs, sometimes called kissing bugs, spread it. when the bug bites you, usually on your face, it leaves behind infected waste. you can get the infection if you rub it in your eyes or nose, the bite wound or a cut. the disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. if you notice symptoms, they might include fever flu-like symptoms a rash a swollen eyelid these early symptoms usually go away. however, if you don't treat the infection, it stays in your body. later, it can cause serious intestinal and heart problems. a physical exam and blood tests can diagnose it. you may also need tests to see whether the disease has affected your intestines and heart. medicines can kill the parasite, especially early on. you can also treat related problems. for example, a pacemaker helps with certain heart complications. centers for disease control and prevention

MalaCards: Chagas Disease, also known as american trypanosomiasis, is related to sleeping sickness and systemic lupus erythematosus. An important gene associated with Chagas Disease is CYP51A1 (cytochrome P450, family 51, subfamily A, polypeptide 1), and among its related pathways are PAK Pathway and Neuroscience. The compounds cysteine and tyrosine have been mentioned in the context of this disorder. Affiliated tissues include liver, brain and kidney, and related mouse phenotypes are cardiovascular system and vision/eye.

Disease Ontology:⁸ A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily triatominae (family reduviidae), most commonly species belonging to the triatoma, rhodnius, and panstrongylus genera. the symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.

NIH Rare Diseases:⁴³ Chagas disease is caused by the parasite, trypanosoma cruzi. when a triatomine bug (commonly known as a "kissing bug") infected with this parasite bites you, usually on your face, it leaves behind infected waste which can be spread into your eyes, nose, or a wound. chagas disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. symptoms can include fever, flu-like symptoms, a rash or swollen eyelid. early symptoms usually go away but if not treated, the infection can later cause serious intestinal and heart problems  chagas disease is common in latin america but not in the united states. last updated: 3/14/2012

CDC:³ Chagas disease is named after the Brazilian physician Carlos Chagas, who discovered the disease in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors and is found only in the Americas (mainly, in rural areas of Latin America where poverty is widespread). Chagas disease (T. cruzi infection) is also referred to as American trypanosomiasis.

Wikipedia:⁶⁴ Chagas disease /ˈtʃɑːɡəs/, or American trypanosomiasis, is a tropical parasitic disease caused by... more...

External Ids:

Disease Ontology8 DOID:12140 ICD9CM27 086.2 SNOMED-CT57 54570006, 186817003

ICD10 via Orphanet26 B57 ICD1025 B57, B57.2 B57.3, B57.4, B57.5, more UMLS61 C0007932

Search GEO for disease gene expression data for Chagas Disease.