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MCID: CHG001
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Chagas Disease malady |
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Sources: 6Disease Ontology, 30NIH Rare Diseases, 23MedlinePlus, 2CDC, 44Wikipedia, 22MalaCards See all sources Export this MalaCard |
MedlinePlus: Chagas disease is caused by a parasite. it is common in latin america but not in the united states. infected blood-sucking bugs, sometimes called kissing bugs, spread it. when an infected bug bites you, usually on your face, it leaves behind infected waste. you can get the infection if you rub it in your eyes or nose, the bite wound or a cut. the disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy.
if you notice symptoms, they might include
fever
flu-like symptoms
a rash
a swollen eyelid
these early symptoms usually go away. however, if you don't treat the infection, it remains. later, it can cause serious intestinal and heart problems. medicines can kill the parasite, especially early on. you can also treat related problems. for example, a pacemaker helps with certain heart complications.
centers for disease control and prevention23
MalaCards: Chagas Disease, also known as chagas' disease with digestive system involvement, is related to sleeping sickness and onchocerciasis. An important gene associated with Chagas Disease is SRM (spermidine synthase), and among its related pathways are Apoptosis and survival Anti-apoptotic action of membrane-bound ESR1 and Pancreatic cancer. The compounds cyclophosphamide and nadph have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and skeletal muscle, and related mouse phenotypes are respiratory system and renal/urinary system. Disease Ontology: A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily triatominae (family reduviidae), most commonly species belonging to the triatoma, rhodnius, and panstrongylus genera. the symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.6 NIH Rare Diseases: Chagas disease is caused by the parasite, Trypanosoma cruzi. When a triatomine bug (commonly known as a "kissing bug") infected with this parasite bites you, usually on your face, it leaves behind infected waste which can be spread into your eyes, nose, or a wound. Chagas disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. Symptoms can include fever, flu-like symptoms, a rash or swollen eyelid. Early symptoms usually go away but if not treated, the infection can later cause serious intestinal and heart problems Chagas disease is common in Latin America but not in the United States.30 CDC: Chagas disease is named after the Brazilian physician Carlos Chagas, who discovered the disease in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors and is found only in the Americas (mainly, in rural areas of Latin America where poverty is widespread). Chagas disease (T. cruzi infection) is also referred to as American trypanosomiasis.2 Wikipedia: Chagas disease (pron.: /ˈʃɑːɡəs/; Portuguese: doença de Chagas [duˈẽsɐ dʒi ˈʃagɐʃ],...44 more... |
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Sources: 6Disease Ontology, 30NIH Rare Diseases, 8DISEASES, 32Novoseek , 23MedlinePlus, 2CDC, 43UMLS, 40SNOMED-CT, 19ICD9CM See all sources |
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Sources: 4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT See all sources |
Approved drugs:Search CenterWatch for chagas disease Drug clinical trials:Search ClinicalTrials for chagas disease Search NIH Clinical Center for chagas disease Search CenterWatch for chagas disease |
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Sources: 22MalaCards See all sources |
MalaCards organs/tissues related to chagas disease:22Brain, Heart, Skeletal muscle, Monocytes, T cells, B cells
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Sources: 25MGI See all sources |
MGI Mouse Phenotypes related to chagas disease:25 (show all 25)
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Sources: 35PubMed See all sources |
Articles related to chagas disease:(show top 50) (show all 86)
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Sources: 1BioGPS See all sources |
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Sources: 10EMD Millipore, 20KEGG, 41Thomson Reuters, 36QIAGEN See all sources |
Pathways related to chagas disease according to GeneDecks:(show top 50) (show all 565)
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Sources: 32Novoseek , 34PharmGKB, 9DrugBank, 18HMDB, 42Tocris Bioscience See all sources |
Compounds related to chagas disease according to GeneDecks:(show top 50) (show all 348)
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Sources: 12Gene Ontology See all sources |
Cellular components related to chagas disease according to GeneDecks:
Biological processes related to chagas disease according to GeneDecks:(show top 50) (show all 84)
Molecular functions related to chagas disease according to GeneDecks:(show all 10)
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