MCID: CHR289
MIFTS: 16

Charcot-Marie-Tooth Neuropathy Type 1a malady

Neuronal diseases category

Summaries for Charcot-Marie-Tooth Neuropathy Type 1a

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Charcot-Marie-Tooth Neuropathy Type 1a, also known as charcot-marie-tooth neuropathy, type 1a, is related to neuropathy and charcot-marie-tooth disease. An important gene associated with Charcot-Marie-Tooth Neuropathy Type 1a is PMP22 (peripheral myelin protein 22), and among its related pathways is Neural Crest Differentiation. The compounds dihydrotestosterone and dihydroprogesterone have been mentioned in the context of this disorder.

Aliases & Classifications for Charcot-Marie-Tooth Neuropathy Type 1a

About this section
Sources:
20GeneTests, 44Novoseek, 60UMLS
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

charcot-marie-tooth neuropathy type 1a 20
charcot-marie-tooth neuropathy, type 1a 44
charcot-marie-tooth disease, type ia 60


Related Diseases for Charcot-Marie-Tooth Neuropathy Type 1a

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Charcot-Marie-Tooth Disease Type 3 family:

Charcot-Marie-Tooth Disease Type 2 Charcot-Marie-Tooth Disease Type 1
Charcot-Marie-Tooth Disease Type X Charcot-Marie-Tooth Disease Intermediate Type
Charcot-Marie-Tooth Disease Type 4 Charcot-Marie-Tooth Disease
Charcot-Marie-Tooth Neuropathy Type 1 Charcot-Marie-Tooth Neuropathy Type 2
Charcot-Marie-Tooth Neuropathy Type 2a Charcot-Marie-Tooth Neuropathy Type 2e/1f
Charcot-Marie-Tooth Neuropathy Type 4 Charcot-Marie-Tooth Neuropathy Type 4a
Charcot-Marie-Tooth Neuropathy Type 4c Charcot-Marie-Tooth Neuropathy Type 4h
Charcot-Marie-Tooth Neuropathy Type 4j Charcot-Marie-Tooth Neuropathy X Type 1
Charcot-Marie-Tooth Neuropathy X Type 5 Dnm2-Related Intermediate Charcot-Marie-Tooth Neuropathy
Charcot-Marie-Tooth Disease Dominant Intermediate 1 Charcot-Marie-Tooth Disease Dominant Intermediate 2
Charcot-Marie-Tooth Disease Dominant Intermediate 3 Charcot-Marie-Tooth Disease Type 1a
Charcot-Marie-Tooth Disease Type 1b Charcot-Marie-Tooth Disease Type 1c
Charcot-Marie-Tooth Disease Type 1d Charcot-Marie-Tooth Disease Type 1e
Charcot-Marie-Tooth Disease Type 1f Charcot-Marie-Tooth Disease Type 2a
Charcot-Marie-Tooth Disease Type 2b Charcot-Marie-Tooth Disease Type 2b1
Charcot-Marie-Tooth Disease Type 2b2 Charcot-Marie-Tooth Disease Type 2c
Charcot-Marie-Tooth Disease Type 2d Charcot-Marie-Tooth Disease Type 2e
Charcot-Marie-Tooth Disease Type 2f Charcot-Marie-Tooth Disease Type 2g
Charcot-Marie-Tooth Disease Type 2h Charcot-Marie-Tooth Disease Type 2i
Charcot-Marie-Tooth Disease Type 2j Charcot-Marie-Tooth Disease Type 2k
Charcot-Marie-Tooth Disease Type 4b1 Charcot-Marie-Tooth Disease Type 4b2
Charcot-Marie-Tooth Disease Type 4e Charcot-Marie-Tooth Neuropathy X
Intermediate Charcot-Marie-Tooth Neuropathy Charcot-Marie-Tooth Neuropathy Multi-Gene Panels
Charcot-Marie-Tooth Neuropathy Type 1e Charcot-Marie-Tooth Neuropathy Type 4b2
Charcot-Marie-Tooth Neuropathy Type 2b2 Charcot-Marie-Tooth Neuropathy Type 2b1
Charcot-Marie-Tooth Neuropathy Type 2g Charcot-Marie-Tooth Neuropathy Type 2l
Charcot-Marie-Tooth Neuropathy Type 2i/2j Charcot-Marie-Tooth Neuropathy Type 2h/2k
Charcot-Marie-Tooth Neuropathy X Type 2 Charcot-Marie-Tooth Neuropathy X Type 3
Charcot-Marie-Tooth Neuropathy X Type 4 Prps1-Related Charcot-Marie-Tooth Neuropathy X Type 5
Yars-Related Intermediate Charcot-Marie-Tooth Neuropathy Mpz-Related Intermediate Charcot-Marie-Tooth Neuropathy
Charcot-Marie-Tooth Neuropathy Type 2n Kars-Related Intermediate Charcot-Marie-Tooth Neuropathy
Charcot-Marie-Tooth Neuropathy Type 2d Gdap1-Related Intermediate Charcot-Marie-Tooth Neuropathy
Charcot-Marie-Tooth Neuropathy Type 2o Charcot-Marie-Tooth Neuropathy Type 2p
Charcot-Marie-Tooth Neuropathy Type 4b3 Charcot-Marie-Tooth Neuropathy Type 1b
Charcot-Marie-Tooth Neuropathy Type 1c Charcot-Marie-Tooth Neuropathy Type 2a2
Charcot-Marie-Tooth Neuropathy Type 2b Charcot-Marie-Tooth Neuropathy Type 2c
Charcot-Marie-Tooth Neuropathy Type 4b1 Charcot-Marie-Tooth Neuropathy Type 4d
Charcot-Marie-Tooth Neuropathy Type 4e Charcot-Marie-Tooth Neuropathy Type 4f
charcot-marie-tooth neuropathy type 1a Charcot-Marie-Tooth Neuropathy Type 1d
Charcot-Marie-Tooth Disease, Type 2a1 Charcot-Marie-Tooth Disease, Type 2a2
Charcot-Marie-Tooth Disease, Recessive Intermediate C Charcot-Marie-Tooth Disease, Dominant Intermediate C
Charcot-Marie-Tooth Disease, Type 2r Charcot-Marie-Tooth Disease, Recessive Intermediate, a
Charcot-Marie-Tooth Disease, Dominant Intermediate a Charcot-Marie-Tooth Disease, Recessive Intermediate, B
Charcot-Marie-Tooth Disease, Dominant Intermediate B Charcot-Marie-Tooth Disease, Type 4f
Charcot-Marie-Tooth Disease, Type 4b3 Surf1-Related Charcot-Marie-Tooth Disease Type 4

Diseases related to Charcot-Marie-Tooth Neuropathy Type 1a via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 26)
idRelated DiseaseScoreTop Affiliating Genes
1neuropathy31.4MPZ, PMP22
2charcot-marie-tooth disease30.6PMP22, MPZ
3tooth disease30.6MPZ, PMP22
4charcot-marie-tooth disease type 1a30.6PMP22, CMT1A
5peripheral neuropathy10.6
6duchenne muscular dystrophy10.5
7muscular dystrophy10.5
8hereditary neuropathy with liability to pressure palsies10.0PMP22
9polyradiculoneuropathy10.0PMP22
10pelizaeus-merzbacher disease10.0MPZ
11encephalomyelitis10.0MPZ
12charcot-marie-tooth neuropathy type 110.0MPZ, PMP22
13motor peripheral neuropathy10.0PMP22, MPZ
14charcot-marie-tooth disease type 4e10.0PMP22, MPZ
15chronic inflammatory demyelinating polyradiculoneuropathy10.0PMP22, MPZ
16charcot-marie-tooth disease type 310.0PMP22, MPZ
17brachial plexus neuropathy10.0MPZ, PMP22
18hereditary neuropathies10.0MPZ, PMP22
19diabetic neuropathy10.0PMP22, MPZ
20sensory peripheral neuropathy10.0MPZ, PMP22
21charcot-marie-tooth disease type 1e10.0PMP22, CMT1A
22neuropathy, recurrent, with pressure palsies10.0PMP22, CMT1A
23neurilemmoma10.0MPZ, PMP22
24guillain-barre syndrome10.0PMP22, MPZ
25neuritis10.0PMP22, MPZ
26polyneuropathy10.0MPZ, PMP22

Graphical network of the top 20 diseases related to Charcot-Marie-Tooth Neuropathy Type 1a:



Diseases related to charcot-marie-tooth neuropathy type 1a

Clinical Features for Charcot-Marie-Tooth Neuropathy Type 1a

About this section

Drugs & Therapeutics for Charcot-Marie-Tooth Neuropathy Type 1a

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Charcot-Marie-Tooth Neuropathy Type 1a

Drug clinical trials:

Search ClinicalTrials for Charcot-Marie-Tooth Neuropathy Type 1a

Search NIH Clinical Center for Charcot-Marie-Tooth Neuropathy Type 1a

Search CenterWatch for Charcot-Marie-Tooth Neuropathy Type 1a

Genetic Tests for Charcot-Marie-Tooth Neuropathy Type 1a

About this section
Sources:
20GeneTests
See all sources

Genetic tests related to Charcot-Marie-Tooth Neuropathy Type 1a:

id Genetic test Affiliating Genes
1 Charcot-Marie-Tooth Neuropathy Type 1a20 PMP22

Anatomical Context for Charcot-Marie-Tooth Neuropathy Type 1a

About this section

Animal Models for Charcot-Marie-Tooth Neuropathy Type 1a or affiliated genes

About this section

Publications for Charcot-Marie-Tooth Neuropathy Type 1a

About this section

Genetic Variations for Charcot-Marie-Tooth Neuropathy Type 1a

About this section

Expression for genes affiliated with Charcot-Marie-Tooth Neuropathy Type 1a

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Charcot-Marie-Tooth Neuropathy Type 1a

Search GEO for disease gene expression data for Charcot-Marie-Tooth Neuropathy Type 1a.

Pathways for genes affiliated with Charcot-Marie-Tooth Neuropathy Type 1a

About this section
Sources:
37NCBI BioSystems Database
See all sources

Pathways related to Charcot-Marie-Tooth Neuropathy Type 1a according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3MPZ, PMP22

Compounds for genes affiliated with Charcot-Marie-Tooth Neuropathy Type 1a

About this section
Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 24HMDB
See all sources

Compounds related to Charcot-Marie-Tooth Neuropathy Type 1a according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1dihydrotestosterone44 28 11 2412.3MPZ, PMP22
2dihydroprogesterone449.2MPZ, PMP22
3ganglioside449.0MPZ, PMP22

GO Terms for genes affiliated with Charcot-Marie-Tooth Neuropathy Type 1a

About this section

Products for genes affiliated with Charcot-Marie-Tooth Neuropathy Type 1a

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Charcot-Marie-Tooth Neuropathy Type 1a

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet