MCID: CHR289
MIFTS: 12

Charcot-Marie-Tooth Neuropathy Type 1a malady

Neuronal category

Summaries for Charcot-Marie-Tooth Neuropathy Type 1a

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33MalaCards
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MalaCards: Charcot-Marie-Tooth Neuropathy Type 1a, also known as charcot-marie-tooth neuropathy, type 1a, is related to charcot-marie-tooth neuropathy type 1 and tooth disease. An important gene associated with Charcot-Marie-Tooth Neuropathy Type 1a is PMP22 (peripheral myelin protein 22), and among its related pathways is Neural Crest Differentiation. The compounds dihydrotestosterone and dihydroprogesterone have been mentioned in the context of this disorder.

Aliases & Classifications for Charcot-Marie-Tooth Neuropathy Type 1a

Sources:
20GeneTests, 45Novoseek, 61UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal


Aliases & Descriptions:

charcot-marie-tooth neuropathy type 1a 20
charcot-marie-tooth neuropathy, type 1a 45
charcot-marie-tooth disease, type ia 61


Related Diseases for Charcot-Marie-Tooth Neuropathy Type 1a

Sources:
17GeneCards, 18GeneDecks
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Diseases in the charcot-marie-tooth disease family:

charcot-marie-tooth disease type 2 charcot-marie-tooth disease type 1
charcot-marie-tooth disease type x charcot-marie-tooth disease intermediate type
charcot-marie-tooth disease type 4 charcot-marie-tooth disease type 3
charcot-marie-tooth neuropathy type 1 charcot-marie-tooth neuropathy type 2
charcot-marie-tooth neuropathy type 2a charcot-marie-tooth neuropathy type 2e/1f
charcot-marie-tooth neuropathy type 4 charcot-marie-tooth neuropathy type 4a
charcot-marie-tooth neuropathy type 4c charcot-marie-tooth neuropathy type 4h
charcot-marie-tooth neuropathy type 4j charcot-marie-tooth neuropathy x type 1
charcot-marie-tooth neuropathy x type 5 charcot-marie-tooth disease dominant intermediate 1
charcot-marie-tooth disease dominant intermediate 2 charcot-marie-tooth disease dominant intermediate 3
charcot-marie-tooth disease type 1a charcot-marie-tooth disease type 1b
charcot-marie-tooth disease type 1c charcot-marie-tooth disease type 1d
charcot-marie-tooth disease type 1e charcot-marie-tooth disease type 1f
charcot-marie-tooth disease type 2a charcot-marie-tooth disease type 2b
charcot-marie-tooth disease type 2b1 charcot-marie-tooth disease type 2b2
charcot-marie-tooth disease type 2c charcot-marie-tooth disease type 2d
charcot-marie-tooth disease type 2e charcot-marie-tooth disease type 2f
charcot-marie-tooth disease type 2g charcot-marie-tooth disease type 2h
charcot-marie-tooth disease type 2i charcot-marie-tooth disease type 2j
charcot-marie-tooth disease type 2k charcot-marie-tooth disease type 4b1
charcot-marie-tooth disease type 4b2 charcot-marie-tooth disease type 4b2 with early-onset glaucoma
charcot-marie-tooth disease type 4e charcot-marie-tooth disease with ptosis and parkinsonism
charcot-marie-tooth disease with pyramidal features, autosomal dominant charcot-marie-tooth neuropathy x
intermediate charcot-marie-tooth neuropathy charcot-marie-tooth neuropathy multi-gene panels
charcot-marie-tooth neuropathy type 1e charcot-marie-tooth neuropathy type 4b2
charcot-marie-tooth neuropathy type 2b2 charcot-marie-tooth neuropathy type 2b1
charcot-marie-tooth neuropathy type 2g charcot-marie-tooth neuropathy type 2l
charcot-marie-tooth neuropathy type 2i/2j charcot-marie-tooth neuropathy type 2h/2k
charcot-marie-tooth neuropathy x type 2 charcot-marie-tooth neuropathy x type 3
charcot-marie-tooth neuropathy x type 4 charcot-marie-tooth neuropathy type 2n
charcot-marie-tooth neuropathy type 2d charcot-marie-tooth neuropathy type 2o
charcot-marie-tooth neuropathy type 2p charcot-marie-tooth neuropathy type 4b3
charcot-marie-tooth neuropathy type 1b charcot-marie-tooth neuropathy type 1c
charcot-marie-tooth neuropathy type 2a2 charcot-marie-tooth neuropathy type 2b
charcot-marie-tooth neuropathy type 2c charcot-marie-tooth neuropathy type 4b1
charcot-marie-tooth neuropathy type 4d charcot-marie-tooth neuropathy type 4e
charcot-marie-tooth neuropathy type 4f charcot-marie-tooth neuropathy type 1a
charcot-marie-tooth neuropathy type 1d charcot-marie-tooth disease, type 2a1
charcot-marie-tooth disease, type 2a2 charcot-marie-tooth disease, recessive intermediate c
charcot-marie-tooth disease, dominant intermediate c charcot-marie-tooth disease, type 2r
charcot-marie-tooth disease, recessive intermediate, a charcot-marie-tooth disease, dominant intermediate a
charcot-marie-tooth disease, recessive intermediate, b charcot-marie-tooth disease, dominant intermediate b
charcot-marie-tooth disease, type 4f charcot-marie-tooth disease, type 4b3

Diseases related to Charcot-Marie-Tooth Neuropathy Type 1a via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 27)
idRelated DiseaseScoreTop Affiliating Genes
1charcot-marie-tooth neuropathy type 131.0MPZ, PMP22
2tooth disease30.6PMP22, MPZ
3charcot-marie-tooth disease type 1a30.6PMP22, CMT1A
4chromosome 17p duplication10.6
5duchenne muscular dystrophy10.5
6charcot-marie-tooth neuropathy type 210.5
7charcot-marie-tooth neuropathy type 2p10.5
8hereditary neuropathy with liability to pressure palsies10.0PMP22
9polyradiculoneuropathy10.0PMP22
10pelizaeus-merzbacher disease10.0MPZ
11encephalomyelitis10.0MPZ
12motor peripheral neuropathy10.0PMP22, MPZ
13charcot-marie-tooth disease type 4e10.0PMP22, MPZ
14chronic inflammatory demyelinating polyradiculoneuropathy10.0PMP22, MPZ
15charcot-marie-tooth disease type 310.0PMP22, MPZ
16charcot-marie-tooth disease10.0PMP22, MPZ
17brachial plexus neuropathy10.0PMP22, MPZ
18hereditary neuropathies10.0PMP22, MPZ
19diabetic neuropathy10.0MPZ, PMP22
20sensory peripheral neuropathy10.0PMP22, MPZ
21charcot-marie-tooth disease type 1e10.0PMP22, CMT1A
22neuropathy, recurrent, with pressure palsies10.0PMP22, CMT1A
23neurilemmoma10.0MPZ, PMP22
24guillain-barre syndrome10.0PMP22, MPZ
25neuropathy10.0MPZ, PMP22
26neuritis10.0MPZ, PMP22
27polyneuropathy10.0PMP22, MPZ

Graphical network of the top 20 diseases related to Charcot-Marie-Tooth Neuropathy Type 1a:



Diseases related to charcot-marie-tooth neuropathy type 1a

Clinical Features for Charcot-Marie-Tooth Neuropathy Type 1a

Drugs & Therapeutics for Charcot-Marie-Tooth Neuropathy Type 1a

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Charcot-Marie-Tooth Neuropathy Type 1a

Drug clinical trials:

Search ClinicalTrials for Charcot-Marie-Tooth Neuropathy Type 1a

Search NIH Clinical Center for Charcot-Marie-Tooth Neuropathy Type 1a

Search CenterWatch for Charcot-Marie-Tooth Neuropathy Type 1a

Genetic Tests for Charcot-Marie-Tooth Neuropathy Type 1a

Sources:
20GeneTests
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Genetic tests related to Charcot-Marie-Tooth Neuropathy Type 1a:

id Genetic test Affiliating Genes
1 Charcot-marie-tooth Neuropathy Type 1a20 PMP22

Anatomical Context for Charcot-Marie-Tooth Neuropathy Type 1a

Animal Models for Charcot-Marie-Tooth Neuropathy Type 1a or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Charcot-Marie-Tooth Neuropathy Type 1a

Genetic Variations for Charcot-Marie-Tooth Neuropathy Type 1a

Expression for genes affiliated with Charcot-Marie-Tooth Neuropathy Type 1a

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Charcot-Marie-Tooth Neuropathy Type 1a

Search GEO for disease gene expression data for Charcot-Marie-Tooth Neuropathy Type 1a.

Pathways for genes affiliated with Charcot-Marie-Tooth Neuropathy Type 1a

Sources:
38NCBI BioSystems Database
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Pathways related to Charcot-Marie-Tooth Neuropathy Type 1a according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3MPZ, PMP22

Compounds for genes affiliated with Charcot-Marie-Tooth Neuropathy Type 1a

Sources:
45Novoseek, 29IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Charcot-Marie-Tooth Neuropathy Type 1a according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1dihydrotestosterone45 29 11 2412.3MPZ, PMP22
2dihydroprogesterone459.2MPZ, PMP22
3ganglioside459.0MPZ, PMP22

GO Terms for genes affiliated with Charcot-Marie-Tooth Neuropathy Type 1a

Products for genes affiliated with Charcot-Marie-Tooth Neuropathy Type 1a

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Charcot-Marie-Tooth Neuropathy Type 1a

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet