MCID: CHL056
MIFTS: 38

Cheilitis malady

Oral diseases category
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Summaries for Cheilitis

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Sources:
65Wikipedia, 33MalaCards
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Wikipedia:65 Cheilitis (pronounced /ka??la?t?s/) is inflammation of the lips. This inflammation may include the... more...

MalaCards: Cheilitis, also known as cheilitis nos, is related to actinic cheilitis and cheilitis glandularis. An important gene associated with Cheilitis is CD1A (CD1a molecule), and among its related pathways are Hematopoietic cell lineage and Cell adhesion molecules (CAMs). The compounds aspirin and nitric oxide have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and salivary gland, and related mouse phenotype cellular.

Aliases & Classifications for Cheilitis

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8Disease Ontology, 62UMLS, 58SNOMED-CT, 35MeSH, 40NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Oral diseases


Aliases & Descriptions:

cheilitis 8 62
cheilitis nos 8


External Ids:

Disease Ontology8 DOID:1762
MeSH35 D002613
NCIt40 C79545

Related Diseases for Cheilitis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Cheilitis:



Diseases related to cheilitis

Symptoms for Cheilitis

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Drugs & Therapeutics for Cheilitis

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Cheilitis

Search NIH Clinical Center for Cheilitis

Genetic Tests for Cheilitis

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Anatomical Context for Cheilitis

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33MalaCards
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MalaCards organs/tissues related to Cheilitis:

33
Skin, Testes, Salivary gland, Tongue

Animal Models for Cheilitis or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Cheilitis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053848.4CD274, PDCD1, ITGA3, SERPINB5

Publications for Cheilitis

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52PubMed
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Articles related to Cheilitis:

(show top 50)    (show all 448)
idTitleAuthorsYear
1
How do I manage a patient with angular cheilitis? (23763743)
2013
2
Granulomatous cheilitis with granulomatous vulvitis: a rare association. (24177613)
2013
3
Photodynamic therapy in actinic cheilitis: clinical and anatomopathological evaluation of 19 patients. (22714758)
2012
4
Methyl-aminolevulinate photodynamic therapy for the treatment of actinic cheilitis: a retrospective evaluation of 29 patients. (22370573)
2012
5
Crohn's disease revealed by a cheilitis granulomatosa with favorable evolution by perfusions of infliximab: report of a case and review of the literature. (21809492)
2011
6
Photoletter to the editor: Exfoliative cheilitis associated with titanium dental implants and mercury amalgam. (22408710)
2011
7
Organised angular cheilitis as the initial sign of Crohn's disease in two children. (21243320)
2011
8
Successful treatment of cheilitis granulomatosa with intralesional injection of triamcinolone. (19845820)
2010
9
Actinic cheilitis: evolution to squamous cell carcinoma after carbon dioxide laser vaporization. A study of 43 cases. (19418331)
2010
10
Actinic cheilitis: a treatment review. (20964646)
2010
11
Identification of novel fibroblast growth factor receptor 3 gene mutations in actinic cheilitis and squamous cell carcinoma of the lip. (19327639)
2009
12
Successful treatment of plasma cell cheilitis with topical calcineurin inhibitors. (19958456)
2009
13
Granulomatous cheilitis: a condition that merits inclusion in the differential diagnosis of angioedema. (19274936)
2009
14
Actinic cheilitis treated with one cycle of 5-aminolaevulinic acid-based photodynamic therapy: report of 10 cases. (18489592)
2008
15
Factitious cheilitis: a case report. (18226274)
2008
16
Cheilitis due to olive oil. (18844707)
2008
17
Cheilitis glandularis progressing to squamous cell carcinoma in an hiv-infected patient: case report. (18402312)
2007
18
Treatment of actinic cheilitis using photodynamic therapy with methyl aminolevulinate: report of three cases. (16188193)
2005
19
Cheilitis granulomatosa of Melkersson-Rosenthal syndrome: treatment with intralesional corticosteroid injections. (14980194)
2004
20
Cheilitis glandularis: a case report. (15040488)
2004
21
Cheilitis glandularis: an unusual histopathologic presentation. (12627102)
2003
22
A yoga teacher with persistent cheilitis. (12800469)
2003
23
Eruptive cheilitis: a new adverse effect in reactive HIV-positive patients subjected to high activity antiretroviral therapy (HAART). Presentation of six clinical cases. (11488127)
2001
24
Granulomatous cheilitis and Crohn's disease. (11331931)
2001
25
Recurrent allergic contact dermatitis and cheilitis due to castor oil. (10703646)
2000
26
Angular cheilitis after tonsillectomy. (10472460)
1999
27
Acquired linear anetoderma following angular cheilitis. (9666860)
1998
28
Cheilitis granulomatosa treated with metronidazole. (8534947)
1995
29
Ulcerous granulomatous cheilitis with lymphatic invasion caused by Scopulariopsis brevicaulis infection. (7962740)
1994
30
Allergic contact cheilitis related to university studies. (8088159)
1994
31
Treatment of plasma cell cheilitis with griseofulvin. (8176022)
1994
32
Allergic contact cheilitis from a lipstick containing oxybenzone. (1451504)
1992
33
Case #5. Angular cheilitis. (1410625)
1992
34
Cheilitis glandularis. (9791264)
1992
35
Minocycline in granulomatous cheilitis: experience with 6 cases. (1446091)
1992
36
Actinic cheilitis granulomatosa. (1479115)
1992
37
Cheilitis--part II. (2700683)
1989
38
Persistent swelling of the lower lip. Cheilitis granulomatosa. (3178252)
1988
39
Kveim test reactivity in Melkersson-Rosenthal syndrome (cheilitis granulomatosa). (2416173)
1985
40
Clinical observation on the treatment of exfoliative cheilitis with traditional Chinese medicine. (6570507)
1984
41
Cheilitis antedating Crohn's disease: case report and literature update of oral lesions. (6481118)
1984
42
Chronic granulomatous cheilitis and its relationship to Crohn's disease. (6579479)
1983
43
Erosive cheilitis related to prochlorperazine maleate. (6958296)
1982
44
Solar cheilitis. (7338591)
1981
45
Cheilitis glandularis. (6930075)
1980
46
Staphylococcal cheilitis in the guinea-pig. (853732)
1977
47
Photosensitive cheilitis. Clinical and pathogenetic considerations. (5134900)
1971
48
Cheilitis glandularis, heterotopic salivary glands and squamous cell carcinoma of the lip. (13935463)
1962
49
Cheilitis due to coffee. (13079301)
1953
50
Cheilitis as predominant symptom of pellagra. (14789438)
1950

Variations for Cheilitis

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Expression for genes affiliated with Cheilitis

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cheilitis

Search GEO for disease gene expression data for Cheilitis.

Pathways for genes affiliated with Cheilitis

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50PathCards, 30KEGG, 55Reactome, 53QIAGEN
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Compounds for genes affiliated with Cheilitis

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45Novoseek, 51PharmGKB, 29IUPHAR, 24HMDB, 11DrugBank
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Compounds related to Cheilitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1aspirin45 51 29 2412.0CHKB, SERPINB5
2nitric oxide45 24 1110.3CD274, CHKB, SERPINB5

GO Terms for genes affiliated with Cheilitis

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16Gene Ontology
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Cellular components related to Cheilitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098979.5CD274, PDCD1

Biological processes related to Cheilitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1T cell costimulationGO:0312959.5CD274, PDCD1

Molecular functions related to Cheilitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.9CD274, CD1A, PDCD1, ITGA3, SERPINB5

Products for genes affiliated with Cheilitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cheilitis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet