Aliases & Classifications for Cheilitis

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Aliases & Descriptions for Cheilitis:

Name: Cheilitis 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:1762
ICD1027 K13.0
MeSH36 D002613
NCIt42 C79545
UMLS65 C0007971

Summaries for Cheilitis

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Disease Ontology:10 A lip disease characterized by the inflammation of the lips; which may include the perioral skin, the vermilion border and the labial mucosa.

MalaCards based summary: Cheilitis is related to herpes simplex and lipomatosis. An important gene associated with Cheilitis is CAST (Calpastatin), and among its related pathways are Inhibition of Ribosome Biogenesis by p14(ARF) and Aurora A signaling. Affiliated tissues include skin, brain and breast, and related mouse phenotypes are digestive/alimentary and cellular.

Wikipedia:68 Cheilitis is inflammation of the lips. This inflammation may include the perioral skin (the skin around... more...

Related Diseases for Cheilitis

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Diseases related to Cheilitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 432)
idRelated DiseaseScoreTop Affiliating Genes
1herpes simplex30.2MDM2, SUMO1, TP53
2lipomatosis30.2MSH2, TP53
3hepatocellular carcinoma29.0IFNA2, MDM2, MMP9, MSH2, TP53
4angular cheilitis12.6
5cheilitis glandularis12.5
6peeling skin with leukonychia, acral punctate keratoses, cheilitis, and knuckle pads12.5
7actinic cheilitis12.5
8peeling skin-leukonuchia-acral punctate keratoses-cheilitis-knuckle pads syndrome12.3
9melkersson-rosenthal syndrome11.6
10subglottic angioma10.4MDM2, TP53
11spindle cell liposarcoma10.4MDM2, TP53
12chronic duodenal ileus10.4MDM2, TP53
13middle ear squamous cell carcinoma10.4MDM2, TP53
14pulmonary immaturity10.4MDM2, TP53
15familial congenital fourth cranial nerve palsy10.4MSH2, TP53
16common bile duct disease10.4MDM2, TP53
17myocardium cancer10.4KRT6A, TP53
18soft tissue sarcoma childhood10.4MDM2, TP53
19merrf syndrome10.4MDM2, TP53
20schwannoma of twelfth cranial nerve10.4MDM2, TP53
21colonic l-cell glucagon-like peptide producing tumor10.3MSH2, TP53
22sebaceous breast carcinoma10.3MDM2, TP53
23breast adenomyoepithelial adenosis10.3MDM2, TP53
24immunodeficiency 1210.3
25liver rhabdomyosarcoma10.3MDM2, TP53
26anterior spinal artery syndrome10.3MDM2, TP53
27prostatitis10.3
28autosomal dominant complex spastic paraplegia type 9a10.3MMP9, TP53
29hypertensive heart disease10.3KRT16, KRT6A
30breast cancer10.3
31adult astrocytic tumour10.2MDM2, TP53
32leukemia10.2
33vulvar clear cell hidradenocarcinoma10.2KRT10, TP53
34bacterial vaginosis10.2MDM2, MSH2, TP53
35prostate cancer10.2
36lymphoma10.2
37thyroiditis10.2
38benign mesenchymoma10.2KRT10, TP53
39placental insufficiency10.2MDM2, MSH2, TP53
40juvenile astrocytoma10.2MDM2, TP53
41hepatitis10.2
42adenocarcinoma10.2
43retinitis10.2
44endotheliitis10.2
45clove syndrome, somatic10.1KRT10, TP53
46hepatocellular adenoma10.1MDM2, MMP9, TP53
47homocystinuria10.1MMP9, TP53
48cell type cancer10.1MDM2, MMP9, TP53
49small cell cancer of the lung, somatic10.1MDM2, MMP9, TP53
50chancroid10.1IFNA2, TP53

Graphical network of the top 20 diseases related to Cheilitis:



Diseases related to cheilitis

Symptoms for Cheilitis

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Drugs & Therapeutics for Cheilitis

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Drugs for Cheilitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Imiquimodapproved, investigationalPhase 413199011-02-657469
Synonyms:
1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine
1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
1-isobutyl-1H-imidazo(4,5-c)quinolin-4-amine
1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
3M Brand of Imiquimod
4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline
4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline
99011-02-6
AC-529
AC1L1N2I
AC1Q4YO9
Aldara
Aldara (TN)
Aldara, Imiquimod
BB_SC-2107
BIDD:GT0859
Beselna
C056493
CHEBI:36704
CHEMBL1282
CID57469
D02500
DB00724
DZ-2636
FT-0080222
HMS2090M14
I06-0624
 
I06-2289
I0747
I5159_SIGMA
IMIQUIMOD
Imiquimod
Imiquimod (JAN/USAN/INN)
Imiquimod [USAN:INN]
Imiquimod acetate
Imiquimodum
LS-178395
MLS000083577
MTD-39
MolPort-002-507-845
NCGC00070736-02
NSC369100
R 837
R-837
S 26308
S-26308
S1211_Selleck
SMR000048307
STK583860
TL8006059
TMX-101
UNII-P1QW714R7M
Vyloma
ZINC19632912
Zartra
Zyclara
imiquimod
2
Aminolevulinic acidapprovedPhase 4, Phase 1142106-60-5137
Synonyms:
106-60-5
35BEC718-C970-426A-9859-BF58284C60B4
5-ALA
5-Amino-4-oxo-Pentanoate
5-Amino-4-oxo-Pentanoic acid
5-Amino-4-oxopentanoate
5-Amino-4-oxopentanoic acid
5-Amino-4-oxovalerate
5-Amino-4-oxovaleric acid
5-Amino-Levulinate
5-Amino-Levulinic acid
5-Aminolaevulinate
5-Aminolaevulinic acid
5-Aminolevulinate
5-Aminolevulinate hydrochloride
5-Aminolevulinic acid
5-amino-levulinate
5451-09-2
AC-054
AC1L18K9
AKOS003587520
ALA
ALA-PDT
Aladerm
Amino-levulinic acid
Aminolevulinate
Aminolevulinic
Aminolevulinic acid
BIDD:GT0260
BSPBio_003407
C00430
CCRIS 8958
CHEBI:17549
CHEMBL601
CID137
CPD000857229
 
D07567
DALA
DB00855
DivK1c_006954
EINECS 203-414-1
I14-10101
KBio1_001898
KBio2_002062
KBio2_004630
KBio2_007198
KBio3_002627
KBioGR_001176
KBioSS_002062
Kerastick
LMFA01100055
LS-101793
Levulan Kerastick
Levulinic acid, 5-amino- (8CI)
MLS001333097
MLS001333098
MolPort-001-788-423
NCGC00178086-01
Pentanoic acid, 5-amino-4-oxo- (9CI)
SAM002589919
SMR000857229
SPBio_001843
ST50819610
SpecPlus_000858
Spectrum2_001662
Spectrum3_001654
Spectrum4_000618
Spectrum5_001505
Spectrum_001582
UNII-88755TAZ87
delta-ALA
delta-Aminolevulinate
delta-Aminolevulinic acid
delta-aminolevulinic acid
3Immunologic FactorsPhase 4, Phase 218483
4Photosensitizing AgentsPhase 4, Phase 1374
5Adjuvants, ImmunologicPhase 41783
6Dermatologic AgentsPhase 4, Phase 14555
7Methyl 5-aminolevulinatePhase 4, Phase 152
8interferonsPhase 41930
9
Tacrolimusapproved, investigationalPhase 21023104987-11-3445643, 439492, 445647
Synonyms:
(-)-FK 506
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
104987-11-3
109581-93-3 (Hydrate)
15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,
3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c] [1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
8-DEETHYL-8-[but-3-enyl]-ascomycin
AC-1182
AC1L1K7H
AC1L97GB
AC1L9IBU
AKOS005145901
Advagraf
Ambap104987-11-3
Ambap5429
BCBcMAP01_000194
BRD-K35452788-001-02-1
BSPBio-001279
BSPBio_001279
Bio-0921
Bio2_000470
Bio2_000950
C01375
C44H69NO10
CCRIS 7124
CHEBI:100924
CHEBI:61049
CHEMBL1200738
CID11158639
CID11556866
CID439492
CID445643
CID5372
CID5472317
CID6426916
CID6436007
CID6473866
CID6536850
CID6610362
CID6912836
CID9832283
CID9853905
CID9918805
CID9940643
CID9963169
CPD-10016
CPD000466356
D08556
DB00864
DivK1c_001040
FK 506
FK-506
FK5
FK506
FR 900506
FR-900506
FR900506
 
FT-0082660
Fk-506
Fujimycin
Graceptor
HMS1362O21
HMS1792O21
HMS1990O21
HMS2051C18
HMS2093M19
HMS503O21
Hecoria
IDI1_001040
IDI1_002225
K506
KBio1_001040
KBio2_000619
KBio2_003187
KBio2_005755
KBio3_001097
KBio3_001098
KBioGR_000619
KBioSS_000619
L 679934
L-679934
LCP-Tacro
LMPK04000003
LS-64247
MLS000759471
MLS001424054
Modigraf
MolPort-003-666-518
NCGC00163470-01
NCGC00163470-02
NCGC00163470-03
NCGC00163470-04
NCGC00179232-01
NChemBio.2007.16-comp1
NINDS_001040
NSC717865
Prograf
Prograf (TN)
Protopic
Protopy
S5003_Selleck
SAM001246677
SMR000466356
Tacarolimus
Tacrolimus
Tacrolimus (INN)
Tacrolimus (Prograf?)
Tacrolimus (anhydrous)
Tacrolimus Hydrate
Tacrolimus anhydrous
Tacrolimus hydrate
Tsukubaenolide
UNII-Y5L2157C4J
nchembio.2007.23-comp2
tacrolimus
tacrolimus hydrate
10Calcineurin InhibitorsPhase 21223
11Immunosuppressive AgentsPhase 210422

Interventional clinical trials:

idNameStatusNCT IDPhase
1Treatment Study for Actinic Cheilitis Comparing Imiquimod 5% and Photodynamic TherapyCompletedNCT00849992Phase 4
2Photodynamic Therapy to Treat Actinic Damage in Patients With Squamous Cell Carcinoma (SCC) of the LipCompletedNCT00868088Phase 4
3Photodynamic Therapy (PDT) With Levulan and Blue Light for the Treatment of Actinic CheilitisNot yet recruitingNCT02409732Phase 4
4Topical Tacrolimus 0.1% Ointment For Treatment Of Cutaneous Crohn's DiseaseCompletedNCT01233570Phase 2
5Study of Methyl Aminolaevulinate Photodynamic Therapy With and Without Er:YAG Laser in Actinic CheilitisCompletedNCT02198469Phase 1

Search NIH Clinical Center for Cheilitis

Genetic Tests for Cheilitis

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Anatomical Context for Cheilitis

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MalaCards organs/tissues related to Cheilitis:

33
Skin, Brain, Breast, Heart, T cells, Liver, B cells

Animal Models for Cheilitis or affiliated genes

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MGI Mouse Phenotypes related to Cheilitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053817.1KRT16, MDM2, MMP9, MSH2, SUMO1, TP53
2MP:00053846.6CAST, KRT16, MDM2, MMP9, MSH2, SERPINB5

Publications for Cheilitis

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Articles related to Cheilitis:

(show top 50)    (show all 501)
idTitleAuthorsYear
1
Effects of radiological extent on neutrophil/lymphocyte ratio in pulmonary sarcoidosis. (26957274)
2016
2
Improvement in Pulmonary Function of Chronic Obstructive Pulmonary Disease (COPD) Patients With Osteoporotic Vertebral Compression Fractures (OVCFs) After Kyphoplasty Under Local Anesthesia. (25785335)
2015
3
Interferon gamma and Interleukin 10 polymorphisms in Brazilian patients with systemic lupus erythematosus. (24443230)
2014
4
In palindromic rheumatism, hand joint involvement and positive anti-CCP antibodies predict RA development after 1A year of follow-up. (24623460)
2014
5
Genetic variability at COMT but not at OPRM1 and UGT2B7 loci modulates morphine analgesic response in acute postoperative pain. (23686330)
2013
6
Cryptococcosis, silicosis, and tuberculous pseudotumor in the same pulmonary lobe. (24310636)
2013
7
Mycotic Celiac Artery Aneurysm Following Infective Endocarditis: Successful Treatment Using N-butyl Cyanoacrylate with Embolization Coils. (23555513)
2012
8
Multivessel intralobar pulmonary sequestration. (22450090)
2012
9
Interleukin-8 is associated with proliferation, migration, angiogenesis and chemosensitivity in vitro and in vivo in colon cancer cell line models. (20648559)
2011
10
Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) inhibits cell growth in a mouse mammary gland cancer cell line. (19660859)
2010
11
CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex. (20523938)
2010
12
Editorial: Reflux, dyspepsia, and Rome III (or Rome IV?). (21131930)
2010
13
HLA and KIR frequencies in Sicilian Centenarians. (20426625)
2010
14
Echolalia in the language development of autistic individuals: a bibliographical review. (19838574)
2009
15
Proteasomal degradation of TRIM5alpha during retrovirus restriction. (18497858)
2008
16
Host-cell specific effects of the nicotinic acetylcholine receptor chaperone RIC-3 revealed by a comparison of human and Drosophila RIC-3 homologues. (18208544)
2008
17
Paraneoplastic limbic encephalitis as a cause of new onset of seizures in a patient with non-small cell lung carcinoma: a case report. (18700972)
2008
18
Cognitive decline and markers of inflammation and hemostasis: the Edinburgh Artery Study. (17493189)
2007
19
Antigenic determinants to GAD autoantibodies in patients with type 1 diabetes with and without autoimmune thyroid disease. (17130557)
2006
20
Molecular analysis and characterization of PrEC, commercially available prostate epithelial cells. (16618209)
2006
21
The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus. (15797963)
2005
22
Differential expression of multiple transglutaminases in human colon: impaired keratinocyte transglutaminase expression in ulcerative colitis. (15753534)
2005
23
Lymphangiosarcoma in a 3.5-year-old Bullmastiff bitch with vaginal prolapse, primary lymph node fibrosis and other congenital defects. (16300186)
2005
24
Association between cytochrome P450 2D6 genotype and harm avoidance. (15108188)
2004
25
Dominant-negative CREB inhibits heparanase functionality and melanoma cell invasion. (15368349)
2004
26
The impact of Helicobacter pylori infection on coronary heart disease in a Korean population. (15505430)
2004
27
Modulatory effects of leptin on leydig cell function of normal and hyperleptinemic rats. (14657608)
2003
28
Type I interferon production by plasmacytoid dendritic cells and monocytes is triggered by viruses, but the level of production is controlled by distinct cytokines. (12162875)
2002
29
Mice with a severe deficiency of the endothelial protein C receptor gene develop, survive, and reproduce normally, and do not present with enhanced arterial thrombosis after challenge. (12353077)
2002
30
Endonuclein is a cell cycle regulated WD-repeat protein that is up-regulated in adenocarcinoma of the pancreas. (11850830)
2002
31
Hydrogen peroxide and superoxide anion production by polymorphonuclear neutrophils in patients with chronic periapical granuloma, before and after surgical treatment. (11355101)
2001
32
Electron microscopic immunolocalization of basic fibroblast growth factor in peripheral nerves. (11151411)
2000
33
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. (10706276)
2000
34
PAX3 and PAX7 exhibit conserved cis-acting transcription repression domains and utilize a common gain of function mechanism in alveolar rhabdomyosarcoma. (10439042)
1999
35
Testosterone and leptin in a group of Chinese with and without diabetes. (11228760)
1999
36
High titer, prostate specific antigen-specific human IgG production by hu-PBL-SCID mice immunized with antigen-mouse IgG2a complex-pulsed autologous dendritic cells. (9820559)
1998
37
Evaluation of long-term prognosis in patients with heart failure: is cardiac imaging with iodine-123 metaiodobenzylguanidine useful?]. (9666388)
1998
38
Regional odontodysplasia: report of four cases. (9524463)
1997
39
The use of angiotensin-converting enzyme inhibitors in the treatment of heart failure in hospital practice. (9338025)
1997
40
Mu- and delta-opioid receptor antagonists precipitate similar withdrawal phenomena in butorphanol and morphine dependence. (8833225)
1996
41
Three Japanese patients with Crigler-Najjar syndrome type I carry an identical nonsense mutation in the gene for UDP-glucuronosyltransferase. (8527799)
1995
42
Growth hormone specifically stimulates the expression of low density lipoprotein receptors in human hepatoma cells. (7649083)
1995
43
Ezrin has properties to self-associate at the plasma membrane. (7844168)
1994
44
Circulating burst-forming-unit erythroid and the responsiveness to recombinant human erythropoietin in patients on regular hemodialytic treatment. (1436306)
1992
45
TGF-beta regulation of epithelial cell proliferation. (1637556)
1992
46
Delayed endolymphatic hydrops and its relationship to MeniAcre's disease. (2241008)
1990
47
A case of temporal encephalocele. (2383870)
1990
48
3-Hydroxy-3-methylglutaryl-coenzyme A lyase deficiency: biochemical studies and family investigation of four generations. (2116546)
1990
49
Gene organization of DC and DX subregions of the human major histocompatibility complex. (3858830)
1985
50
Amish albinism: a distinctive autosomal recessive phenotype. (5516239)
1970

Variations for Cheilitis

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Expression for genes affiliated with Cheilitis

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Search GEO for disease gene expression data for Cheilitis.

Pathways for genes affiliated with Cheilitis

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GO Terms for genes affiliated with Cheilitis

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Cellular components related to Cheilitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nucleolusGO:00057309.2MDM2, SUMO1, TP53

Biological processes related to Cheilitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1double-strand break repairGO:00063029.8MSH2, TP53
2intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorGO:00427719.6MSH2, TP53
3intermediate filament cytoskeleton organizationGO:00451049.6KRT16, KRT6A
4nucleotide-excision repairGO:00062899.6SUMO1, TP53

Sources for Cheilitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet