MCID: CHC001
MIFTS: 51

Chickenpox malady

Infectious diseases, Skin diseases categories

Aliases & Classifications for Chickenpox

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Summaries for Chickenpox

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MedlinePlus:32 Chickenpox is an infection caused by the varicella-zoster virus. most cases are in children under age 15, but older children and adults can get it. it spreads very easily from one person to another. the classic symptom of chickenpox is an uncomfortable, itchy rash. the rash turns into fluid-filled blisters and eventually into scabs. it usually shows up on the face, chest, and back and then spreads to the rest of the body. other symptoms include fever headache tiredness loss of appetite chickenpox is usually mild and lasts 5 to 10 days. calamine lotions and oatmeal baths can help with itching. acetaminophen can treat the fever. do not use aspirin for chickenpox; that combination can cause reye syndrome. chickenpox can sometimes cause serious problems. adults, babies, teenagers, pregnant women, and those with weak immune systems tend to get sicker from it. they may need to take antiviral medicines. once you catch chickenpox, the virus usually stays in your body. you probably will not get chickenpox again, but the virus can cause shingles in adults. a chickenpox vaccine can help prevent most cases of chickenpox, or make it less severe if you do get it. centers for disease control and prevention

MalaCards based summary: Chickenpox, also known as varicella, is related to herpes zoster and fasciitis, and has symptoms including anorexia, myalgia and nausea. An important gene associated with Chickenpox is ACTC1 (actin, alpha, cardiac muscle 1), and among its related pathways is Primary immunodeficiency. The drugs acyclovir and acyclovir sodium and the compounds s 100 and mucicarmine have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and brain, and related mouse phenotypes are no phenotypic analysis and normal.

Disease Ontology:8 A viral infectious disease that results in infection located in skin, has material basis in human herpesvirus 3, which is transmitted by direct contact with secretions from the rash, or transmitted by droplet spread of respiratory secretions. the infection has symptom anorexia, has symptom myalgia, has symptom nausea, has symptom fever, has symptom headache, has symptom sore throat, and has symptom blisters.

Wikipedia:64 Chickenpox, also known as varicella, is a highly contagious disease caused by the initial infection with... more...

Related Diseases for Chickenpox

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Diseases related to Chickenpox via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 341)
idRelated DiseaseScoreTop Affiliating Genes
1herpes zoster31.3DNAJC28, CD4
2fasciitis31.0ACTC1
3purpura31.0CD79A
4thrombophlebitis30.9APOH
5meningoencephalitis30.7CD4, CD79A
6measles30.6CD79A, CD4
7protein c deficiency30.6APOH, PROS1
8pneumonia30.6MUC1, CD4, CD79A
9protein s deficiency30.5APOH, PROS1
10mumps30.4CD79A, CD4
11toxoplasmosis30.4CD4, CD79A
12meningitis30.2CD4, CD79A
13pulmonary embolism30.2PROS1, APOH
14vasculitis30.1CD79A, PROS1, APOH
15tetanus30.1CD79A, CD4
16thrombophilia30.1APOH, PROS1
17neuropathy30.0CD79A, CD4
18cryptosporidiosis29.9CD4, CD79A
19gastritis29.9CD79A, CD4
20diphtheria29.8CD79A, CD4
21hepatitis b29.8GPT, CD4, CD79A
22syphilis29.7APOH, CD4, CD79A
23lupus erythematosus29.6APOH, PROS1, CD79A
24systemic lupus erythematosus29.5CD79A, CD4, APOH
25thrombocytopenia29.4CD79A, CD4, APOH, GPT
26ipex syndrome29.2CD79A, CD4, GPT
27rheumatoid arthritis29.2CD79A, CD4, APOH
28glomus tumor10.5ACTC1
29encephalitis10.5
30retinitis10.5
31hemangioma10.4ACTC1
32histoplasmosis10.4CD4
33keratitis10.4
34renal cell carcinoma10.4CD4
35spindle cell carcinoma10.3ACTC1, MUC1
36spindle cell sarcoma10.3MUC1, ACTC1
37dermatofibrosarcoma protuberans10.3ACTC1, MUC1
38rhabdoid tumor10.3MUC1, ACTC1
39hemangiopericytoma10.3MUC1, ACTC1
40malignant mixed mullerian tumor10.3MUC1, ACTC1
41tubular adenocarcinoma10.3ACTC1, MUC1
42angiosarcoma10.3MUC1, ACTC1
43malignant peripheral nerve sheath tumor10.3MUC1, ACTC1
44abrikosov's tumor10.3MUC1, ACTC1
45giant cell tumor10.3MUC1, ACTC1
46mucoepidermoid carcinoma10.3MUC1, ACTC1
47toxic shock syndrome10.3
48stromal keratitis10.3
49neurofibroma10.3MUC1, ACTC1
50malignant fibroxanthoma10.3MUC1, ACTC1

Graphical network of the top 20 diseases related to Chickenpox:



Diseases related to chickenpox

Symptoms for Chickenpox

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Symptoms:

 8 (show all 7)
  • anorexia
  • myalgia
  • nausea
  • fever
  • headache
  • sore throat
  • blisters

Drugs & Therapeutics for Chickenpox

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Drug clinical trials:

Search ClinicalTrials for Chickenpox

Search NIH Clinical Center for Chickenpox

Inferred drug relations via UMLS61/NDF-RT40:

Genetic Tests for Chickenpox

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Anatomical Context for Chickenpox

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MalaCards organs/tissues related to Chickenpox:

31
Skin, Brain, Liver, Testes, Eye, Lung, Breast, T cells, Neutrophil

FMA organs/tissues related to Chickenpox:

14
Skin

Animal Models for Chickenpox or affiliated genes

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MGI Mouse Phenotypes related to Chickenpox:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.2CD79A, CD4, PROS1, MUC1
2MP:00028737.7CD79A, CD4, ACTC1, PROS1, MUC1
3MP:00053767.1APOH, MUC1, PROS1, ACTC1, CD4, CD79A

Publications for Chickenpox

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Articles related to Chickenpox:

(show top 50)    (show all 519)
idTitleAuthorsYear
1
Does chickenpox cause childhood stroke? (25758313)
2015
2
Chickenpox complicated by pneumococcal meningitis: A rare coinfection. (25282451)
2014
3
Varicella zoster virus: chickenpox and shingles. (24734838)
2014
4
Acute venous sinus thrombosis after chickenpox infection. (25856952)
2014
5
Natural alteration of antibody titers in a patient with immunoglobulin A deficiency after chickenpox over a 10-year period. (22181566)
2011
6
Retinitis and optic neuritis in a child with chickenpox: case report and review of literature. (20622712)
2010
7
Hemorrhagic Pericarditis in a child with primary varicella infection (chickenpox). (19332925)
2009
8
Exposition to chickenpox of two children with autoinflammatory syndromes under treatment with anakinra. (18172653)
2008
9
Chickenpox in adults - clinical management. (18555533)
2008
10
Chickenpox: very low mortality in France and the USA. (17460860)
2007
11
Occupationally related outbreak of chickenpox in an intensive care unit. (17709931)
2007
12
Acute retinal necrosis complicating chickenpox in a healthy adult--a case report and review of literature. (17984490)
2007
13
Delayed internal ophthalmoplegia and amblyopia following chickenpox. (16691403)
2006
14
Chickenpox in a geriatric patient. (16686890)
2006
15
Should acyclovir be prescribed for immunocompetent children presenting with chickenpox? (15908639)
2005
16
Delayed disseminated Staphylococcus aureus infection following chickenpox. (15151591)
2004
17
Managing shingles and postherpetic neuralgia. Reactivation of the chickenpox virus causes severe pain and rash in older adults. (15153382)
2004
18
A household study of chickenpox in Guinea-Bissau: intensity of exposure is a determinant of severity. (12423611)
2002
19
Chickenpox. (12603904)
2002
20
Deaths from chickenpox. Healthcare workers should not be forgotten. (11887882)
2002
21
The magnitude of variation in temperature within a year has an effect on the seasonal variations of chickenpox incidence in Japan. (11349977)
2001
22
Serotesting versus presumptive varicella vaccination of adolescents with a negative or uncertain history of chickenpox. (11137902)
2001
23
Cost effectiveness of vaccination strategies in adults without a history of chickenpox. (10924649)
2000
24
Managing exposure to chickenpox during pregnancy. New program. (9585843)
1998
25
Hemolytic anemia associated with cold agglutinin during chickenpox and a review of the literature. (9544167)
1998
26
Molecular biology of varicella-zoster virus. A review prepared for the UK Advisory Group on Chickenpox. (9514102)
1998
27
Acute childhood hemiplegia associated with chickenpox. (9568925)
1998
28
A boy with chickenpox whose fingers peeled. (9635952)
1998
29
Chickenpox immunisation in New Zealand. (9734530)
1998
30
Licensed preparations against hepatitis A and chickenpox: vaccine update--Part 2. (9051961)
1996
31
Surgical implications of necrotizing fasciitis in children with chickenpox. (8863250)
1996
32
The protective effect of immunologic boosting against zoster: an analysis in leukemic children who were vaccinated against chickenpox. (8568309)
1996
33
Acyclovir in chickenpox. (8660091)
1996
34
Acyclovir for childhood chickenpox. Cost is unjustified. (7833700)
1995
35
Chickenpox: an error in diagnosis by Hermann Boerhaave? (11616372)
1995
36
Immunisation against chickenpox. (7827547)
1995
37
Anti-epileptic therapy and fatal chickenpox. (8290426)
1993
38
Chickenpox in pregnancy. Pneumonitis more severe. (8518662)
1993
39
Chickenpox stroke in an adult. (8414047)
1993
40
Purpura fulminans due to protein S deficiency following chickenpox. (1386247)
1992
41
Low antibody avidity in elderly chickenpox patients. (1321222)
1992
42
Subconjunctival hemorrhage in chickenpox. (2041675)
1991
43
Orchitis in chickenpox. (2282240)
1990
44
Chickenpox pneumonia: an association with pregnancy. (2330558)
1990
45
Chickenpox: where do we stand with treatment? (2319406)
1990
46
Transmission of chickenpox in a school setting prior to the observed exanthem. (2556025)
1989
47
Should children in renal failure be immunised against chickenpox before receiving a renal transplant. (2642094)
1989
48
Antiviral treatment in chickenpox and herpes zoster. (3339143)
1988
49
Treatment and prognosis of chickenpox in adult renal transplant recipients on cyclosporin. (3122120)
1987
50
Infantile herpes zoster ophthalmicus and acute hemiparesis following intrauterine chickenpox. (3498130)
1987

Variations for Chickenpox

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Expression for genes affiliated with Chickenpox

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Search GEO for disease gene expression data for Chickenpox.

Pathways for genes affiliated with Chickenpox

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Pathways related to Chickenpox according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.0CD79A, CD4

Compounds for genes affiliated with Chickenpox

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Compounds related to Chickenpox according to GeneCards Suite gene sharing:

(show top 50)    (show all 66)
idCompoundScoreTop Affiliating Genes
1s 1004410.1MUC1, ACTC1
2mucicarmine4410.1ACTC1, MUC1
3b 723449.9MUC1, ACTC1
4nash449.9GPT, ACTC1
5gluten449.9CD79A, APOH
6methanol44 2410.8ACTC1, APOH
7lactulose449.7GPT, CD79A
8clarithromycin44 1110.6CD79A, GPT
9isoniazid44 50 1111.6CD79A, GPT
10cardiolipin44 1110.6APOH, CD79A
11reticulin449.5MUC1, ACTC1, CD79A
12biotin44 24 1111.5CD79A, ACTC1, MUC1
13galactose449.5MUC1, APOH, CD79A
14sialic acid449.5MUC1, CD79A, APOH
15folate449.4MUC1, CD79A, APOH
16phospholipid449.4PROS1, MUC1, APOH
17ethanol44 50 24 1112.4GPT, MUC1, APOH
18ivig449.4GPT, APOH, CD79A
19warfarin44 50 24 1112.4GPT, CD79A, APOH
20vitamin b12449.4APOH, GPT, CD79A
21azathioprine44 1 50 1112.4APOH, GPT, CD79A
22dihydrotestosterone44 28 24 1112.4CD79A, MUC1, PROS1
23prednisolone44 28 1111.4APOH, GPT, CD79A
24valproate449.3CD79A, GPT
25hyaluronic acid44 2410.3GPT, CD79A, MUC1
26phosphorus449.3APOH, GPT
27glycogen44 2410.3MUC1, ACTC1, GPT
28fibrinogen449.2CD79A, GPT, APOH
29vitamin d449.1CD79A, PROS1, GPT
30hemocyanin449.1MUC1, CD4, CD79A
31mannan449.1CD79A, MUC1, CD4
32steroid449.0ACTC1, APOH, PROS1, CD79A
33mannose449.0CD79A, APOH, CD4
34testosterone44 60 24 1112.0CD79A, PROS1, MUC1, ACTC1
35paraffin449.0CD79A, MUC1, ACTC1
36estrogen449.0APOH, CD79A, MUC1, ACTC1
37methotrexate50 44 1111.0MUC1, APOH, CD79A, GPT
38dexamethasone44 50 28 1112.0MUC1, PROS1, ACTC1, CD79A
39neopterin448.9CD4, GPT, CD79A
40polysaccharide448.9CD4, MUC1, CD79A
41progesterone44 28 60 24 1112.9APOH, ACTC1, MUC1, CD4
42arginine448.8APOH, GPT, PROS1, CD79A
43glucose448.8ACTC1, MUC1, APOH, GPT, PROS1
44formaldehyde44 249.7CD79A, MUC1, ACTC1, CD4
45vegf448.7APOH, CD79A, PROS1, MUC1, ACTC1
46heparin44 28 24 1111.6CD79A, PROS1, APOH, CD4
47glutamate448.4GPT, APOH, CD4, CD79A
48cholesterol44 28 24 1111.3GPT, CD4, PROS1, APOH, MUC1
49calcium44 50 24 1111.2APOH, MUC1, CD4, PROS1, ACTC1
50creatinine448.2GPT, APOH, MUC1, PROS1, ACTC1, CD79A

GO Terms for genes affiliated with Chickenpox

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Cellular components related to Chickenpox according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Golgi lumenGO:00057969.6PROS1, MUC1

Molecular functions related to Chickenpox according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glycoprotein bindingGO:00019489.3CD4, APOH

Sources for Chickenpox

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet