MCID: CHC001
MIFTS: 51

Chickenpox malady

Infectious category

Summaries for Chickenpox

Sources:
8Disease Ontology, 34MedlinePlus, 3CDC, 64Wikipedia, 33MalaCards
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MedlinePlus:34 Chickenpox is an infection caused by the varicella-zoster virus. most cases are in children under age 15, but older children and adults can get it. it spreads very easily from one person to another. the classic symptom of chickenpox is an uncomfortable, itchy rash. the rash turns into fluid-filled blisters and eventually into scabs. it usually shows up on the face, chest, and back and then spreads to the rest of the body. other symptoms include fever headache tiredness loss of appetite chickenpox is usually mild and lasts 5 to 10 days. calamine lotions and oatmeal baths can help with itching. acetaminophen can treat the fever. do not use aspirin for chickenpox; that combination can cause reye syndrome. chickenpox can sometimes causes serious problems. adults, babies, teenagers, pregnant women, and those with weak immune systems tend to get sicker from it. they may need to take antiviral medicines. once you catch chickenpox, the virus usually stays in your body. you probably will not get chickenpox again, but the virus can cause shingles in adults. a chickenpox vaccine can help prevent most cases of chickenpox, or make it less severe if you do get it. centers for disease control and prevention

MalaCards: Chickenpox, also known as varicella, is related to herpes zoster and hepatitis c, and has symptoms including anorexia, myalgia and nausea. An important gene associated with Chickenpox is MRC1 (mannose receptor, C type 1). The drugs acyclovir and acyclovir sodium and the compounds s 100 and reticulin have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and liver.

Disease Ontology:8 A viral infectious disease that results in infection located in skin, has material basis in human herpesvirus 3, which is transmitted by direct contact with secretions from the rash, or transmitted by droplet spread of respiratory secretions. the infection has symptom anorexia, has symptom myalgia, has symptom nausea, has symptom fever, has symptom headache, has symptom sore throat, and has symptom blisters.

CDC:3 Chickenpox is a very contagious disease caused by the varicella-zoster virus (VZV). It causes a blister-like rash, itching, tiredness, and fever. The rash appears first on the trunk and face and can spread over the entire body causing between 250 and 500 itchy blisters...more

Wikipedia:64 Chickenpox (or chicken pox) is a highly contagious disease caused by primary infection with varicella... more...

Aliases & Classifications for Chickenpox

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 34MedlinePlus, 61UMLS, 57SNOMED-CT, 27ICD9CM, 35MeSH, 25ICD10
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Related Diseases for Chickenpox

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Chickenpox:



Diseases related to chickenpox

Clinical Features for Chickenpox

Sources:
8Disease Ontology
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Symptoms:

8 (show all 7)
  • anorexia
  • myalgia
  • nausea
  • fever
  • headache
  • sore throat
  • blisters

Drugs & Therapeutics for Chickenpox

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Chickenpox

Drug clinical trials:

Search ClinicalTrials for Chickenpox

Search NIH Clinical Center for Chickenpox

Search CenterWatch for Chickenpox

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Chickenpox

Anatomical Context for Chickenpox

Sources:
14FMA, 33MalaCards
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MalaCards organs/tissues related to Chickenpox:

33
Skin, Liver, Lung, Breast, Tonsil, T cells, B cells, Fetal liver, Fetal lung

FMA organs/tissues related to Chickenpox:

14
Skin

Animal Models for Chickenpox or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Chickenpox

Sources:
51PubMed
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Articles related to Chickenpox:

(show top 50)    (show all 506)
idTitleAuthorsYear
1
Occupationally related outbreak of chickenpox in hospital staff: a learning experience. (24298507)
2013
2
An observational study of complications in chickenpox with special reference to unusual complications in an apex infectious disease hospital, Kolkata, India. (23793307)
2013
3
Unusually severe varicella zoster (VZV) virus viral (aseptic) meningitis in an unimmunized, immunocompetent host with chickenpox. (21724043)
2011
4
Giant cell hepatitis and autoimmune hemolytic anemia after chickenpox. (21332002)
2010
5
Towards evidence based medicine for paediatricians. How effective is varicella-zoster immunoglobulin (VZIG) in preventing chickenpox in neonates following perinatal exposure? (19542068)
2009
6
First reported cluster of overwhelming group A streptococcal septicaemia and associated chickenpox infection in the UK. (21686953)
2009
7
Delayed disseminated Staphylococcus aureus infection following chickenpox. (15151591)
2004
8
Managing shingles and postherpetic neuralgia. Reactivation of the chickenpox virus causes severe pain and rash in older adults. (15153382)
2004
9
Severe adult chickenpox infection requiring intensive care. (15008570)
2004
10
Deep venous thrombosis and pulmonary embolism following chickenpox. (15479579)
2004
11
Chickenpox and pneumonia following varicella vaccine. (15301022)
2004
12
Profound lymphocytosis preceding chickenpox. (15247623)
2004
13
Fatal outbreak of chickenpox (varicella-zoster virus infection) among institutionalised adults with learning difficulties. (15481205)
2004
14
Chickenpox. (12967388)
2003
15
Chickenpox worldwide. (12867846)
2003
16
Chickenpox neuroretinitis in a 9 year old child. (11914224)
2002
17
Deaths from Chickenpox. Extracorporeal membrane oxygenation has important role. (11887884)
2002
18
Controlled trial of acyclovir for chickenpox evaluating time of initiation and duration of therapy and viral resistance. (11642624)
2001
19
Deaths from chickenpox in England and Wales 1995-7: analysis of routine mortality data. (11701571)
2001
20
Chickenpox: A parent's perspective. (20177530)
2000
21
Impact on immunization of seasonal cycle of chickenpox. (11484809)
2000
22
Variation in risk for nosocomial chickenpox after inadvertent exposure. (10706806)
2000
23
New vaccine information materials for hepatitis B, Haemophilus influenzae type b (Hib), and varicella (chickenpox) vaccines, and revised vaccine information materials for measles, mumps, rubella (MMR) vaccines. Centers for Disease Control and Prevention (CDC), Department of Health and Human Services. Notice. (10557592)
1999
24
Chickenpox in four adult renal transplant recipients. (10500608)
1999
25
School and daycare exclusion policies for chickenpox: A rational approach. (23284229)
1999
26
Revisited measles and chickenpox dynamics through orthogonal transformation. (10074391)
1999
27
Hemolytic anemia associated with cold agglutinin during chickenpox and a review of the literature. (9544167)
1998
28
Ultrasonography in the diagnosis of chickenpox-related osteomyelitis. (9440105)
1998
29
The challenge of chickenpox. Vaccine is best bet against this childhood illness. (9555287)
1998
30
The course of chickenpox in asthmatic children receiving inhaled budesonide. (9002107)
1997
31
Chickenpox. (9206294)
1997
32
Solitary cutaneous cryptococcosis resembling chickenpox: a case report. (9030381)
1997
33
Licensed preparations against hepatitis A and chickenpox: vaccine update--Part 2. (9051961)
1996
34
Chickenpox in pregnancy: how dangerous? (8762292)
1996
35
Chickenpox in mid-trimester pregnancy: always innocent? (8698155)
1996
36
Chickenpox and steroid cards. Amended card is used in Oxford. (8664690)
1996
37
Immunisation against chickenpox. (7827547)
1995
38
Severe chickenpox during treatment with corticosteroids. Latex assay shows false negatives. (7866186)
1995
39
Case report: the pulmonary lesions of chickenpox pneumonia--revisited. (8062004)
1994
40
A measure of family disruption for use in chickenpox and other childhood illnesses. (8171351)
1994
41
Monocular blindness from central retinal artery occlusion associated with chickenpox. (8291581)
1994
42
So your child has chickenpox.... (8213482)
1993
43
Childhood chickenpox: its impact on child and family. (8477888)
1993
44
Acyclovir in chickenpox. (1343813)
1992
45
Orchitis in chickenpox. (2282240)
1990
46
Chickenpox pneumonia: an association with pregnancy. (2688179)
1989
47
Acetaminophen: more harm than good for chickenpox? (2656959)
1989
48
Use of acyclovir to treat chickenpox in pregnancy. (3125914)
1988
49
Epidemiology of chickenpox in England and Wales, 1967-85. (3128363)
1988
50
Risk of herpes zoster in children with leukemia: varicella vaccine compared with history of chickenpox. (3455669)
1986

Genetic Variations for Chickenpox

Expression for genes affiliated with Chickenpox

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Chickenpox

Search GEO for disease gene expression data for Chickenpox.

Pathways for genes affiliated with Chickenpox

Compounds for genes affiliated with Chickenpox

Sources:
45Novoseek, 24HMDB
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Compounds related to Chickenpox according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1s 1004510.3ACTC1, MUC1
2reticulin4510.1ACTC1, MUC1
3nash4510.1ACTC1, GPT
4mucicarmine4510.0MUC1, ACTC1
5galactose4510.0MRC1, APOH, MUC1
6nucleoside459.7DTYMK, RRM1, GPT, GPI
7creatinine459.5ACTC1, GPI, GPT, MUC1, PROS1, APOH
8glucose459.5APOH, PROS1, MUC1, GPT, GPI, ACTC1
9glycogen45 2410.4MUC1, GPT, GPI, ACTC1

GO Terms for genes affiliated with Chickenpox

Sources:
16Gene Ontology
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Biological processes related to Chickenpox according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleobase-containing small molecule interconversionGO:01594910.0RRM1, DTYMK
2blood coagulation, intrinsic pathwayGO:0075979.8GP5, APOH

Products for genes affiliated with Chickenpox

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Chickenpox

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet