MCID: CHC001
MIFTS: 60

Chickenpox malady

Infectious diseases, Skin diseases categories
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Summaries for Chickenpox

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MedlinePlus:33 Chickenpox is an infection caused by the varicella-zoster virus. most cases are in children under age 15, but older children and adults can get it. it spreads very easily from one person to another. the classic symptom of chickenpox is an uncomfortable, itchy rash. the rash turns into fluid-filled blisters and eventually into scabs. it usually shows up on the face, chest, and back and then spreads to the rest of the body. other symptoms include fever headache tiredness loss of appetite chickenpox is usually mild and lasts 5 to 10 days. calamine lotions and oatmeal baths can help with itching. acetaminophen can treat the fever. do not use aspirin for chickenpox; that combination can cause reye syndrome. chickenpox can sometimes cause serious problems. adults, babies, teenagers, pregnant women, and those with weak immune systems tend to get sicker from it. they may need to take antiviral medicines. once you catch chickenpox, the virus usually stays in your body. you probably will not get chickenpox again, but the virus can cause shingles in adults. a chickenpox vaccine can help prevent most cases of chickenpox, or make it less severe if you do get it. centers for disease control and prevention

MalaCards based summary: Chickenpox, also known as varicella, is related to herpes zoster and fasciitis, and has symptoms including An important gene associated with Chickenpox is ACTC1 (actin, alpha, cardiac muscle 1), and among its related pathways is Primary immunodeficiency. The drugs acyclovir and acyclovir sodium and the compounds s 100 and mucicarmine have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and tonsil, and related mouse phenotypes are no phenotypic analysis and normal.

Disease Ontology:8 A viral infectious disease that results in infection located in skin, has material basis in human herpesvirus 3, which is transmitted by direct contact with secretions from the rash, or transmitted by droplet spread of respiratory secretions. the infection has symptom anorexia, has symptom myalgia, has symptom nausea, has symptom fever, has symptom headache, has symptom sore throat, and has symptom blisters.

CDC:3 Chickenpox is a very contagious disease caused by the varicella-zoster virus (VZV). It causes a blister-like rash, itching, tiredness, and fever. The rash appears first on the trunk and face and can spread over the entire body causing between 250 and 500 itchy blisters…

Wikipedia:65 Chickenpox is a highly contagious disease caused by primary infection with varicella zoster virus (VZV).... more...

Aliases & Classifications for Chickenpox

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Chickenpox, Aliases & Descriptions:

Name: Chickenpox 8 10 33 62
 
Varicella 8 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases
Anatomical: Skin diseases


External Ids:

Disease Ontology8 DOID:8659
ICD9CM27 052
MeSH34 D002644
ICD1025 B01, B01.8, B01.9

Related Diseases for Chickenpox

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Diseases related to Chickenpox via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 356)
idRelated DiseaseScoreTop Affiliating Genes
1herpes zoster31.3CD4, DNAJC28
2fasciitis31.1ACTC1
3purpura31.0CD79A
4thrombophlebitis30.9APOH
5meningoencephalitis30.7CD79A, CD4
6pneumonia30.6CD4, CD79A, MUC1
7measles30.6CD4, CD79A
8protein c deficiency30.6APOH, PROS1
9protein s deficiency30.5PROS1, APOH
10mumps30.4CD4, CD79A
11toxoplasmosis30.3CD79A, CD4
12pulmonary embolism30.2PROS1, APOH
13vasculitis30.2CD79A, PROS1, APOH
14venous thrombosis30.2APOH, PROS1
15tetanus30.1CD4, CD79A
16meningitis30.1CD79A, CD4
17thrombophilia30.1APOH, PROS1
18neuropathy30.0CD79A, CD4
19cryptosporidiosis30.0CD79A, CD4
20gastritis29.9CD4, CD79A
21diphtheria29.9CD4, CD79A
22infectious mononucleosis29.9CD79A, CD4
23hepatitis b29.8CD79A, CD4, GPT
24syphilis29.7APOH, CD4, CD79A
25lupus erythematosus29.6APOH, CD79A, PROS1
26systemic lupus erythematosus29.5CD4, CD79A, APOH
27thrombocytopenia29.4GPT, APOH, CD4, CD79A
28ipex syndrome29.2GPT, CD4, CD79A
29rheumatoid arthritis29.2CD4, APOH, CD79A
30paraganglioma10.5ACTC1
31retinitis10.5
32hemangioma10.5ACTC1
33encephalitis10.4
34histoplasmosis10.4CD4
35keratitis10.4
36kidney cancer10.4CD4
37spindle cell carcinoma10.3ACTC1, MUC1
38spindle cell sarcoma10.3ACTC1, MUC1
39dermatofibrosarcoma protuberans10.3ACTC1, MUC1
40rhabdoid tumor10.3ACTC1, MUC1
41hemangiopericytoma10.3ACTC1, MUC1
42malignant mixed mullerian tumor10.3ACTC1, MUC1
43stromal keratitis10.3
44tubular adenocarcinoma10.3ACTC1, MUC1
45angiosarcoma10.3ACTC1, MUC1
46malignant peripheral nerve sheath tumor10.3ACTC1, MUC1
47giant cell tumor10.3ACTC1, MUC1
48abrikosov's tumor10.3ACTC1, MUC1
49mucoepidermoid carcinoma10.3MUC1, ACTC1
50neurofibroma10.3MUC1, ACTC1

Graphical network of the top 20 diseases related to Chickenpox:



Diseases related to chickenpox

Symptoms for Chickenpox

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Drugs & Therapeutics for Chickenpox

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Drug clinical trials:

Search ClinicalTrials for Chickenpox

Search NIH Clinical Center for Chickenpox

Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Chickenpox

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Anatomical Context for Chickenpox

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MalaCards organs/tissues related to Chickenpox:

32
Skin, Tonsil, Liver, Testes, Eye, Lung, Breast, T cells, Neutrophil

FMA organs/tissues related to Chickenpox:

14
Skin

Animal Models for Chickenpox or affiliated genes

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MGI Mouse Phenotypes related to Chickenpox:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.2CD79A, CD4, PROS1, MUC1
2MP:00028737.7CD79A, CD4, ACTC1, PROS1, MUC1
3MP:00053767.1APOH, MUC1, PROS1, ACTC1, CD4, CD79A

Publications for Chickenpox

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Articles related to Chickenpox:

(show top 50)    (show all 508)
idTitleAuthorsYear
1
Varicella zoster virus: chickenpox and shingles. (24734838)
2014
2
Natural alteration of antibody titers in a patient with immunoglobulin A deficiency after chickenpox over a 10-year period. (22181566)
2011
3
Retinitis and optic neuritis in a child with chickenpox: case report and review of literature. (20622712)
2010
4
Hemorrhagic Pericarditis in a child with primary varicella infection (chickenpox). (19332925)
2009
5
Exposition to chickenpox of two children with autoinflammatory syndromes under treatment with anakinra. (18172653)
2008
6
Chickenpox in adults - clinical management. (18555533)
2008
7
Chickenpox: very low mortality in France and the USA. (17460860)
2007
8
Occupationally related outbreak of chickenpox in an intensive care unit. (17709931)
2007
9
Acute retinal necrosis complicating chickenpox in a healthy adult--a case report and review of literature. (17984490)
2007
10
Delayed internal ophthalmoplegia and amblyopia following chickenpox. (16691403)
2006
11
Chickenpox in a geriatric patient. (16686890)
2006
12
Should acyclovir be prescribed for immunocompetent children presenting with chickenpox? (15908639)
2005
13
Delayed disseminated Staphylococcus aureus infection following chickenpox. (15151591)
2004
14
Managing shingles and postherpetic neuralgia. Reactivation of the chickenpox virus causes severe pain and rash in older adults. (15153382)
2004
15
A household study of chickenpox in Guinea-Bissau: intensity of exposure is a determinant of severity. (12423611)
2002
16
Chickenpox. (12603904)
2002
17
Deaths from chickenpox. Healthcare workers should not be forgotten. (11887882)
2002
18
Chickenpox vaccine snapped up instantly. (11894640)
2002
19
The magnitude of variation in temperature within a year has an effect on the seasonal variations of chickenpox incidence in Japan. (11349977)
2001
20
Serotesting versus presumptive varicella vaccination of adolescents with a negative or uncertain history of chickenpox. (11137902)
2001
21
Cost effectiveness of vaccination strategies in adults without a history of chickenpox. (10924649)
2000
22
Managing exposure to chickenpox during pregnancy. New program. (9585843)
1998
23
Hemolytic anemia associated with cold agglutinin during chickenpox and a review of the literature. (9544167)
1998
24
Molecular biology of varicella-zoster virus. A review prepared for the UK Advisory Group on Chickenpox. (9514102)
1998
25
Acute childhood hemiplegia associated with chickenpox. (9568925)
1998
26
A boy with chickenpox whose fingers peeled. (9635952)
1998
27
Chickenpox immunisation in New Zealand. (9734530)
1998
28
Licensed preparations against hepatitis A and chickenpox: vaccine update--Part 2. (9051961)
1996
29
Surgical implications of necrotizing fasciitis in children with chickenpox. (8863250)
1996
30
The protective effect of immunologic boosting against zoster: an analysis in leukemic children who were vaccinated against chickenpox. (8568309)
1996
31
Acyclovir in chickenpox. (8660091)
1996
32
Acyclovir for childhood chickenpox. Cost is unjustified. (7833700)
1995
33
Chickenpox: an error in diagnosis by Hermann Boerhaave? (11616372)
1995
34
Immunisation against chickenpox. (7827547)
1995
35
Childhood vaccination against chickenpox: an analysis of benefits and costs. (8201469)
1994
36
Anti-epileptic therapy and fatal chickenpox. (8290426)
1993
37
Chickenpox in pregnancy. Pneumonitis more severe. (8518662)
1993
38
Chickenpox stroke in an adult. (8414047)
1993
39
Purpura fulminans due to protein S deficiency following chickenpox. (1386247)
1992
40
Low antibody avidity in elderly chickenpox patients. (1321222)
1992
41
Subconjunctival hemorrhage in chickenpox. (2041675)
1991
42
Fatal varicella in an adult: case report and review of the gastrointestinal complications of chickenpox. (1866547)
1991
43
Orchitis in chickenpox. (2282240)
1990
44
Chickenpox pneumonia: an association with pregnancy. (2330558)
1990
45
Chickenpox: where do we stand with treatment? (2319406)
1990
46
Transmission of chickenpox in a school setting prior to the observed exanthem. (2556025)
1989
47
Should children in renal failure be immunised against chickenpox before receiving a renal transplant. (2642094)
1989
48
Antiviral treatment in chickenpox and herpes zoster. (3339143)
1988
49
Treatment and prognosis of chickenpox in adult renal transplant recipients on cyclosporin. (3122120)
1987
50
Infantile herpes zoster ophthalmicus and acute hemiparesis following intrauterine chickenpox. (3498130)
1987

Variations for Chickenpox

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Expression for genes affiliated with Chickenpox

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Expression patterns in normal tissues for genes affiliated with Chickenpox

Search GEO for disease gene expression data for Chickenpox.

Pathways for genes affiliated with Chickenpox

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Pathways related to Chickenpox according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.0CD79A, CD4

Compounds for genes affiliated with Chickenpox

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Compounds related to Chickenpox according to GeneCards/GeneDecks:

(show top 50)    (show all 66)
idCompoundScoreTop Affiliating Genes
1s 1004410.1MUC1, ACTC1
2mucicarmine4410.1ACTC1, MUC1
3b 723449.9MUC1, ACTC1
4nash449.9GPT, ACTC1
5gluten449.9CD79A, APOH
6methanol44 2410.8ACTC1, APOH
7lactulose449.7GPT, CD79A
8clarithromycin44 1110.6CD79A, GPT
9isoniazid44 50 1111.6CD79A, GPT
10cardiolipin44 1110.6APOH, CD79A
11reticulin449.5MUC1, ACTC1, CD79A
12biotin44 24 1111.5CD79A, ACTC1, MUC1
13galactose449.5MUC1, APOH, CD79A
14sialic acid449.5MUC1, CD79A, APOH
15folate449.4MUC1, CD79A, APOH
16phospholipid449.4PROS1, MUC1, APOH
17ethanol44 50 24 1112.4GPT, MUC1, APOH
18ivig449.4GPT, APOH, CD79A
19warfarin44 50 24 1112.4GPT, CD79A, APOH
20vitamin b12449.4APOH, GPT, CD79A
21azathioprine44 2 50 1112.4APOH, GPT, CD79A
22dihydrotestosterone44 28 24 1112.4CD79A, MUC1, PROS1
23prednisolone44 28 1111.4APOH, GPT, CD79A
24valproate449.3CD79A, GPT
25hyaluronic acid44 2410.3GPT, CD79A, MUC1
26phosphorus449.3APOH, GPT
27glycogen44 2410.3MUC1, ACTC1, GPT
28fibrinogen449.2CD79A, GPT, APOH
29vitamin d449.1CD79A, PROS1, GPT
30hemocyanin449.1MUC1, CD4, CD79A
31mannan449.1CD79A, MUC1, CD4
32steroid449.0ACTC1, APOH, PROS1, CD79A
33mannose449.0CD79A, APOH, CD4
34testosterone44 61 24 1112.0CD79A, PROS1, MUC1, ACTC1
35paraffin449.0CD79A, MUC1, ACTC1
36estrogen449.0APOH, CD79A, MUC1, ACTC1
37methotrexate50 44 1111.0MUC1, APOH, CD79A, GPT
38dexamethasone44 50 28 1112.0MUC1, PROS1, ACTC1, CD79A
39neopterin448.9CD4, GPT, CD79A
40polysaccharide448.9CD4, MUC1, CD79A
41progesterone44 28 61 24 1112.9APOH, ACTC1, MUC1, CD4
42arginine448.8APOH, GPT, PROS1, CD79A
43glucose448.8ACTC1, MUC1, APOH, GPT, PROS1
44formaldehyde44 249.7CD79A, MUC1, ACTC1, CD4
45vegf448.7APOH, CD79A, PROS1, MUC1, ACTC1
46heparin44 28 24 1111.6CD79A, PROS1, APOH, CD4
47glutamate448.4GPT, APOH, CD4, CD79A
48cholesterol44 28 24 1111.3GPT, CD4, PROS1, APOH, MUC1
49calcium44 50 24 1111.2APOH, MUC1, CD4, PROS1, ACTC1
50creatinine448.2GPT, APOH, MUC1, PROS1, ACTC1, CD79A

GO Terms for genes affiliated with Chickenpox

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Cellular components related to Chickenpox according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Golgi lumenGO:0057969.6PROS1, MUC1

Molecular functions related to Chickenpox according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1glycoprotein bindingGO:0019489.3CD4, APOH

Products for genes affiliated with Chickenpox

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  • Antibodies
  • Proteins
  • Lysates

Sources for Chickenpox

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet