MCID: CHC001
MIFTS: 54

Chickenpox malady

Infectious diseases category

Summaries for Chickenpox

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Sources:
8Disease Ontology, 33MedlinePlus, 3CDC, 63Wikipedia, 32MalaCards
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MedlinePlus:33 Chickenpox is an infection caused by the varicella-zoster virus. most cases are in children under age 15, but older children and adults can get it. it spreads very easily from one person to another. the classic symptom of chickenpox is an uncomfortable, itchy rash. the rash turns into fluid-filled blisters and eventually into scabs. it usually shows up on the face, chest, and back and then spreads to the rest of the body. other symptoms include fever headache tiredness loss of appetite chickenpox is usually mild and lasts 5 to 10 days. calamine lotions and oatmeal baths can help with itching. acetaminophen can treat the fever. do not use aspirin for chickenpox; that combination can cause reye syndrome. chickenpox can sometimes cause serious problems. adults, babies, teenagers, pregnant women, and those with weak immune systems tend to get sicker from it. they may need to take antiviral medicines. once you catch chickenpox, the virus usually stays in your body. you probably will not get chickenpox again, but the virus can cause shingles in adults. a chickenpox vaccine can help prevent most cases of chickenpox, or make it less severe if you do get it. centers for disease control and prevention

MalaCards: Chickenpox, also known as varicella, is related to herpes zoster and pneumonia, and has symptoms including blisters, sore throat and myalgia. An important gene associated with Chickenpox is MRC1 (mannose receptor, C type 1). The drugs acyclovir and acyclovir sodium and the compounds s 100 and reticulin have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and tonsil.

Disease Ontology:8 A viral infectious disease that results in infection located in skin, has material basis in human herpesvirus 3, which is transmitted by direct contact with secretions from the rash, or transmitted by droplet spread of respiratory secretions. the infection has symptom anorexia, has symptom myalgia, has symptom nausea, has symptom fever, has symptom headache, has symptom sore throat, and has symptom blisters.

CDC:3 Chickenpox is a very contagious disease caused by the varicella-zoster virus (VZV). It causes a blister-like rash, itching, tiredness, and fever. The rash appears first on the trunk and face and can spread over the entire body causing between 250 and 500 itchy blisters…

Wikipedia:63 Chickenpox is a highly contagious disease caused by primary infection with varicella zoster virus (VZV).... more...

Aliases & Classifications for Chickenpox

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 33MedlinePlus, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH, 25ICD10
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Related Diseases for Chickenpox

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Chickenpox:



Diseases related to chickenpox

Clinical Features for Chickenpox

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Sources:
8Disease Ontology
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Symptoms:

8 (show all 7)
  • blisters
  • sore throat
  • myalgia
  • nausea
  • headache
  • fever
  • anorexia

Drugs & Therapeutics for Chickenpox

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Chickenpox

Drug clinical trials:

Search ClinicalTrials for Chickenpox

Search NIH Clinical Center for Chickenpox

Search CenterWatch for Chickenpox

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Chickenpox

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Anatomical Context for Chickenpox

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32MalaCards, 14FMA
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MalaCards organs/tissues related to Chickenpox:

32
Skin, Tonsil, Liver, Testes, T cells, Breast, Lung, Eye

FMA organs/tissues related to Chickenpox:

14
Skin

Animal Models for Chickenpox or affiliated genes

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Publications for Chickenpox

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Sources:
50PubMed
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Articles related to Chickenpox:

(show top 50)    (show all 506)
idTitleAuthorsYear
1
Chickenpox in Poland in 2011. (24040715)
2013
2
Focal high-concentration trichloroacetic acid peeling for treatment of atrophic facial chickenpox scar: an open-label study. (22989024)
2012
3
Varicella-zoster virus (chickenpox) infection in pregnancy. (21585641)
2011
4
Ultra-violet radiation is responsible for the differences in global epidemiology of chickenpox and the evolution of varicella-zoster virus as man migrated out of Africa. (21513563)
2011
5
Exposition to chickenpox of two children with autoinflammatory syndromes under treatment with anakinra. (18172653)
2008
6
Chickenpox in adults - clinical management. (18555533)
2008
7
Chickenpox-associated fulminant hepatitis that led to liver transplantation in a 63-year-old woman. (18756459)
2008
8
Risk factors for chickenpox incidence in Taiwan from a large-scale computerized database. (17442073)
2007
9
Pyomyositis secondary to chickenpox. (17895335)
2007
10
My granddaughter was recently visiting and she had chickenpox. I've already had chickenpox, but I'm concerned about getting shingles because I know the two diseases are related. Can I catch shingles from her? (17176523)
2006
11
Shingles. The return of the chickenpox virus. (16675921)
2006
12
Panuveitis as presenting sign of chickenpox in a young child. (16462882)
2006
13
Should acyclovir be prescribed for immunocompetent children presenting with chickenpox? (15908639)
2005
14
History of chickenpox and shingles and prevalence of antibodies to varicella-zoster virus and three other herpesviruses among adults with glioma and controls. (15870157)
2005
15
Correlation of a reported history of chickenpox with seropositive immunity in pregnant women. (16320558)
2005
16
Growth, morbidity and mortality after chickenpox infection in young children in Guinea-Bissau. (16291283)
2005
17
Declining incidence of chickenpox in the absence of universal childhood immunisation. (15383443)
2004
18
Chickenpox or smallpox: the use of the febrile prodrome as a distinguishing characteristic. (15578404)
2004
19
What you need to know about ... chickenpox. (15119258)
2004
20
Adult chickenpox complicated by fatal necrotising pneumonia. (15287836)
2004
21
Chickenpox outbreak in a highly vaccinated school population. (15466125)
2004
22
Chickenpox oesophagitis and haematemesis in an immunocompetent adult. (12099756)
2002
23
Transient remission of intractable systemic-type of juvenile rheumatoid arthritis after chickenpox in a 2-year-old boy. (11208011)
2001
24
Chickenpox: FactSheet. (12105516)
2000
25
Temporal association of chickenpox and meningococcal disease in children: a report of three cases. (10914977)
2000
26
Chickenpox increasingly affects preschool children. (11014039)
2000
27
Acute retinal necrosis syndrome complicating chickenpox. (11296787)
2000
28
Cost of chickenpox in Canada: part I. Cost of uncomplicated cases. (10390252)
1999
29
Chickenpox pneumonia: case report and literature review. (10191458)
1999
30
Molecular biology of varicella-zoster virus. A review prepared for the UK Advisory Group on Chickenpox. (9514102)
1998
31
Cutaneous localization of chronic lymphocytic leukemia at the site of chickenpox. (8996269)
1997
32
Multiple pulmonary nodules after recovery from chickenpox in a patient with chronic lymphocytic leukaemia. (9441126)
1997
33
Varicella vaccine in pregnancy. Testing should be offered to women without a history of chickenpox. (9022462)
1997
34
Development of foot-drop after recovery from chickenpox. (9290972)
1997
35
Acyclovir for childhood chickenpox. Has substantial potential service implications. (7767216)
1995
36
Shift in age in chickenpox. (1357371)
1992
37
Abscess formation as a complication of chickenpox. (1492216)
1992
38
Health and economic cost of chickenpox in child care. (1588878)
1992
39
Chickenpox during pregnancy. (1454115)
1992
40
Use of acyclovir in the treatment of chickenpox. (1557254)
1992
41
Acyclovir in chickenpox. (1557105)
1992
42
Chickenpox in 'immune' hospital employees. (2064664)
1991
43
Transmission of chickenpox in a school setting prior to the observed exanthem. (2556025)
1989
44
Treatment of chickenpox in immunocompromised children. (3044101)
1988
45
Chickenpox in pregnancy. (3130952)
1988
46
Treatment and prognosis of chickenpox in adult renal transplant recipients on cyclosporin. (3122120)
1987
47
Incidence of chickenpox in adults and recruitment of plasma donors for manufacture of zoster immunoglobulin. (3024773)
1986
48
Haemothorax in the course of chickenpox. (3787528)
1986
49
Unusual shingles and chickenpox. (2869372)
1986
50
A cluster of cases of Reye syndrome associated with chickenpox. (7145545)
1982

Genetic Variations for Chickenpox

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Expression for genes affiliated with Chickenpox

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Chickenpox

Search GEO for disease gene expression data for Chickenpox.

Pathways for genes affiliated with Chickenpox

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Compounds for genes affiliated with Chickenpox

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44Novoseek, 24HMDB
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Compounds related to Chickenpox according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1s 1004410.3ACTC1, MUC1
2reticulin4410.1MUC1, ACTC1
3nash4410.1GPT, ACTC1
4mucicarmine4410.0MUC1, ACTC1
5galactose4410.0APOH, MUC1, MRC1
6nucleoside449.7GPI, DTYMK, RRM1, GPT
7creatinine449.5ACTC1, APOH, PROS1, MUC1, GPT, GPI
8glucose449.5ACTC1, APOH, PROS1, MUC1, GPI, GPT
9glycogen44 2410.4MUC1, GPT, GPI, ACTC1

GO Terms for genes affiliated with Chickenpox

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16Gene Ontology
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Biological processes related to Chickenpox according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleobase-containing small molecule interconversionGO:01594910.0RRM1, DTYMK
2blood coagulation, intrinsic pathwayGO:0075979.8GP5, APOH

Products for genes affiliated with Chickenpox

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Chickenpox

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet