CK
MCID: CHK001
MIFTS: 54

Chikungunya (CK) malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Chikungunya

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Aliases & Descriptions for Chikungunya:

Name: Chikungunya 11 48 54 38 13
Chikungunya Fever 11 48 2 68
Ck 48 2
Arbovirus a Chikungunya Type 48
 
Chikungunya Virus Infection 48
Chikv Infection 48
Chik 48

Characteristics:

Orphanet epidemiological data:

54
chikungunya:
Prevalence: <1/1000000 (France),<1/1000000 (Europe); Age of onset: All ages; Age of death: normal life expectancy

Classifications:



External Ids:

Disease Ontology11 DOID:0050012
Orphanet54 ORPHA324625
ICD10 via Orphanet31 A92.0
ICD1030 A92.0

Summaries for Chikungunya

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MedlinePlus:38 Chikungunya is a virus that spread by the same kinds of mosquitoes that spread dengue and zika virus. rarely, it can spread from mother to newborn around the time of birth. it may also possibly spread through infected blood. there have been outbreaks of chikungunya virus in africa, asia, europe, the indian and pacific oceans, the caribbean, and central and south america. most people who are infected will have symptoms, which can be severe. they usually start 3-7 days after being bitten by an infected mosquito. the most common symptoms are fever and joint pain. other symptoms may include headache, muscle pain, joint swelling, and rash. most people feel better within a week. in some cases, however, the joint pain may last for months. people at risk for more severe disease include newborns, older adults, and people with diseases such as high blood pressure, diabetes, or heart disease. a blood test can show whether you have chikungunya virus. there are no vaccines or medicines to treat it. drinking lots of fluids, resting, and taking non-aspirin pain relievers might help. the best way to prevent chikungunya infection is to avoid mosquito bites: use insect repellent wear clothes that cover your arms, legs, and feet stay in places that have air conditioning or that use window and door screens centers for disease control and prevention

MalaCards based summary: Chikungunya, also known as chikungunya fever, is related to measles and rift valley fever, and has symptoms including fever, pruritus and fever. An important gene associated with Chikungunya is OAS3 (2'-5'-Oligoadenylate Synthetase 3), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and Transcription factor regulation in adipogenesis. Affiliated tissues include joint, testes and heart, and related mouse phenotype hematopoietic system.

CDC:2 Click here to view a Digital Press Kit on chikungunya from the CDC News Room.

Disease Ontology:11 A viral infectious disease that results in infection located in joint, has material basis in Chikungunya virus, which is transmitted by Aedes mosquito bite. The infection has symptom fever, has symptom arthralgia, and has symptom maculopapular rash.

Wikipedia:71 Chikungunya is an infection caused by the chikungunya virus (CHIKV). Symptoms include fever and joint... more...

Related Diseases for Chikungunya

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Diseases related to Chikungunya via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 223)
idRelated DiseaseScoreTop Affiliating Genes
1measles29.6IL1B, IL6, TNF
2rift valley fever29.6IL1B, IL6, TNF
3neuropathy29.4IL1B, IL6, TNF
4choroiditis29.4IL1B, IL6, TNF
5rheumatoid arthritis28.7CCL5, CD40LG, IL1B, IL6, MIF, TNF
6ck syndrome12.3
7hypermethioninemia with deficiency of s-adenosylhomocysteine hydrolase10.8
8child syndrome10.8
9isolated hyperckemia10.8
10myocardial infarction10.3
11oculomotor nerve paralysis10.2IL1B, IL6
12acute myocardial infarction10.2
13common peroneal nerve lesion10.2IL1B, IL6
14intussusception10.2IL1B, TNF
15dyslexia 510.2IL6, TNF
16hereditary elliptocytosis10.2BST2, OAS1, OAS3
17aortic atherosclerosis10.2IL6, TNF
18degenerative disc disease10.2IL6, TNF
19tau syndrome10.2IL1B, TNF
20stocco dos santos syndrome10.1IL1B, TNF
21arthritis10.1
22breast apocrine carcinoma in situ10.1CCL5, IL1B, IL6
23unilateral multicystic dysplastic kidney10.1IL6, TNF
24anal paget's disease10.1IL1B, IL6, TNF
25bipolar i disorder10.1IL1B, IL6, TNF
26tinea capitis10.1IL1B, IL6, TNF
27hypoparathyroidism-retardation-dysmorphism syndrome10.1IL1B, IL6, TNF
28hypotrichosis-lymphedema-telangiectasia-renal defect syndrome10.1IL1B, TNF
29mikulicz disease10.1IL1B, IL6, TNF
30acquired thrombocytopenia10.1IL1B, IL6, TNF
31rheumatoid factor-negative juvenile idiopathic arthritis without anti-nuclear antibodies10.1IL1B, IL6, TNF
32vps11-related autosomal recessive hypomyelinating leukodystrophy10.1CCL5, IL6, TNF
33gonococcal endophthalmia10.1IL1B, IL6, TNF
34ectodermal dysplasia bartalos type10.1IL1B, IL6, TNF
35migraine with aura10.1IL1B, IL6, TNF
36autosomal recessive type iv ehlers-danlos syndrome10.1IL1B, IL6, TNF
37keratoconus10.1IL1B, IL6, TNF
38motility-related diarrhea10.1IL1B, IL6, TNF
39splenic artery aneurysm10.1IL1B, IL6, TNF
40inappropriate adh syndrome10.1IL1B, IL6, TNF
41central nervous system lymphoma10.1IL1B, IL6, TNF
42labyrinthitis10.1IL1B, IL6, TNF
43pancreas lymphoma10.1IL1B, IL6, TNF
44thymic neuroendocrine carcinoma10.1IL6, TNF
45blepharochalasis10.1IL1B, IL6, TNF
46chordoid meningioma10.1IL1B, IL6, TNF
47nasopharyngitis10.1IL1B, IL6, TNF
48erb-duchenne and dejerine-klumpke palsies10.1CCL5, IL6, TNF
49infancy electroclinical syndrome10.1IL1B, IL6, TNF
50stenosis of lacrimal sac10.1IL1B, IL6, TNF

Graphical network of the top 20 diseases related to Chikungunya:



Diseases related to chikungunya

Symptoms & Phenotypes for Chikungunya

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Symptoms:

 11
  • fever
  • arthralgia
  • maculopapular rash

UMLS symptoms related to Chikungunya:


fever, pruritus

MGI Mouse Phenotypes related to Chikungunya according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053976.9CCL5, CD40LG, DDX58, IL1B, IL6, MAVS

Drugs & Therapeutics for Chikungunya

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Drugs for Chikungunya (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
chloroquineapproved, vet_approvedPhase 314954-05-72719
Synonyms:
( -)-Chloroquine
(+)-Chloroquine
(-)-Chloroquine
(R)-(-)-Chloroquine
3377 RP opalate
3545-67-3
50-63-5
54-05-7
56598-66-4
58175-86-3
58175-87-4
7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline
7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline
AB00053436
AC1L1EB8
AC1Q2ZA7
AC1Q2ZA8
Amokin
Aralen
Aralen HCl
Arechin
Arechine
Arequin
Arolen
Arthrochin
Artrichin
Avlochlor
Avloclor
BPBio1_000655
BRD-A91699651-065-01-1
BRN 0482809
BSPBio_000595
BSPBio_002001
Bemaco
Bemaphate
Bemasulph
Benaquin
Bipiquin
C07625
C18H26ClN3
CCRIS 3439
CHEBI:3638
CHEMBL76
CID2719
CQ
CU-01000012392-2
Capquin
Chemochin
Chingamin
Chloraquine
Chlorochin
Chlorochine
Chlorochinum
Chloroin
Chloroquin
Chloroquina
Chloroquine
Chloroquine (USP/INN)
Chloroquine (VAN)
Chloroquine Bis-Phosphoric Acid
Chloroquine Phosphate
Chloroquine [USAN:INN:BAN]
Chloroquine phosphate
Chloroquinium
Chloroquinum
Chloroquinum [INN-Latin]
Chlorquin
Cidanchin
Clorochina
Clorochina [DCIT]
Cloroquina
Cloroquina [INN-Spanish]
Cocartrit
D02366
DB00608
Dawaquin
Delagil
Dichinalex
DivK1c_000404
EINECS 200-191-2
Elestol
Gontochin
Gontochin phosphate
HMS2090O03
HSDB 3029
Heliopar
Hydroxychloroquine Sulfate
IDI1_000404
Imagon
 
Ipsen 225
Iroquine
KBio1_000404
KBio2_000592
KBio2_003160
KBio2_005728
KBio3_001221
KBioGR_000778
KBioSS_000592
Khingamin
Klorokin
LS-141726
Lapaquin
Lopac0_000296
Malaquin
Malaquin (*Diphosphate*)
Malaren
Malarex
Mesylith
Miniquine
MolMap_000009
MolPort-001-783-623
N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine
N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine
NCGC00015256-04
NCGC00162120-01
NCI60_000894
NINDS_000404
NSC 187208
NSC14050
NSC187208
Neochin
Nivachine
Nivaquine
Nivaquine B
Pfizerquine
Plaquenil
Prestwick0_000548
Prestwick1_000548
Prestwick2_000548
Prestwick3_000548
Quinachlor
Quinagamin
Quinagamine
Quinercyl
Quingamine
Quinilon
Quinoscan
RP 3377
RP-3377
Resochen
Resochin
Resoquina
Resoquine
Reumachlor
Reumaquin
Rivoquine
Ro 01-6014/N2
Ronaquine
Roquine
SMP2_000034
SN 6718
SN-7618
SPBio_000174
SPBio_002516
ST 21
ST 21 (pharmaceutical)
Sanoquin
Silbesan
Siragan
Solprina
Sopaquin
Spectrum2_000127
Spectrum3_000341
Spectrum4_000279
Spectrum5_000707
Spectrum_000132
Tanakan
Tanakene
Tresochin
Trochin
UNII-886U3H6UFF
W 7618
WIN 244
WLN: T66 BNJ EMY1&3N2&2 IG
chloroquine
nchembio.215-comp4
nchembio.368-comp8
nchembio.87-comp17
{4-[(7-chloroquinolin-4-yl)amino]pentyl}diethylamine
2Anti-Inflammatory Agents, Non-SteroidalPhase 34443
3Antirheumatic AgentsPhase 310956
4Anti-Inflammatory AgentsPhase 310729
5Antiprotozoal AgentsPhase 32051
6Peripheral Nervous System AgentsPhase 323689
7AnalgesicsPhase 311733
8Chloroquine diphosphatePhase 314950-63-5
9AnthelminticsPhase 3446
10Antiparasitic AgentsPhase 32199
11Analgesics, Non-NarcoticPhase 36501
12Anti-Infective AgentsPhase 322062
13AntimalarialsPhase 31246
14Immunoglobulins, IntravenousPhase 1, Phase 2333
15Rho(D) Immune GlobulinPhase 1, Phase 2326
16ImmunoglobulinsPhase 1, Phase 26394
17AntibodiesPhase 1, Phase 26394
18gamma-GlobulinsPhase 1, Phase 2326
19VaccinesPhase 2, Phase 16611
20Pharmaceutical SolutionsPhase 28192
21
Methylprednisoloneapproved, vet_approved119383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
22
Pantoprazoleapproved175102625-70-74679
Synonyms:
102625-70-7
5-(Difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridyl)methyl)sulfinyl)benzimidazole
5-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazole
AC-679
AC1L1IPJ
Astropan
BIDD:GT0003
BRD-A22380646-001-01-5
BSPBio_002320
BY 1023
BY-1023
C11806
C16H15F2N3O4S
CHEBI:519598
CHEBI:7915
CHEMBL1502
CID4679
D05353
DB00213
HMS1922H20
HMS2090H03
HMS2093F14
HSDB 7292
I06-0068
LS-32883
MolPort-003-666-752
MolPort-005-933-577
NCGC00095188-01
 
NCGC00095188-02
NCGC00095188-03
Pantoloc
Pantopan
Pantoprazol
Pantoprazol [INN-Spanish]
Pantoprazole (USAN/INN)
Pantoprazole Na
Pantoprazole Sodium
Pantoprazole Sodium Hydrate
Pantoprazole [USAN:BAN:INN]
Pantoprazole sodium
Pantoprazolum
Pantoprazolum [INN-Latin]
Pantoprozole
Pantor
Pantozol
Protium
Protonix
Protonix I.V.
Protonix IV
SBB070993
SK&F 96022
SK&F-96022
SK-96022
SKF-96022
SPECTRUM1505818
Somac
TL8000127
UNII-D8TST4O562
pantoprazole
23
Prednisoloneapproved, vet_approved119350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
24
Methotrexateapproved15511959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
25
Mechlorethamineapproved39751-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
 
KBioGR_001448
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
β,β'-dichlorodiethyl-N-methylamine
26
Folic Acidapproved, nutraceutical, vet_approved439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
27
leucovorinapproved, Nutraceutical323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
28Antimetabolites12054
29Vitamin B Complex4337
30Prednisolone acetate1193
31Prednisolone hemisuccinate1193
32Antimetabolites, Antineoplastic7361
33Prednisolone phosphate1193
34Methylprednisolone Hemisuccinate1193
35Immunosuppressive Agents13086
36Folic Acid Antagonists2257
37Nucleic Acid Synthesis Inhibitors4962
38Dermatologic Agents5806
39Methylprednisolone acetate1193
40Vitamin B9Nutraceutical4392
41FolateNutraceutical4392

Interventional clinical trials:

(show all 28)
idNameStatusNCT IDPhase
1Study of INTERCEPT Blood System for Red Blood Cells in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections (RedeS)RecruitingNCT03037164Phase 3
2CuraChik : A Trial of the Efficacy and Safety of Chloroquine as Therapeutic Treatment of Chikungunya DiseaseTerminatedNCT00391313Phase 3
3Clinical Evaluation of Anti-CHIKV Hyperimmune Intravenous ImmunoglobulinsUnknown statusNCT02230163Phase 1, Phase 2
4Phase II Study to Evaluate Safety and Immunogenicity of a Chikungunya VaccineRecruitingNCT02861586Phase 2
5Trial for Safety and Immunogenicity of a Chikungunya Vaccine, VRC-CHKVLP059-00-VP, in Healthy AdultsActive, not recruitingNCT02562482Phase 2
6Study of a Live Attenuated Chikungunya Vaccine in a Previously Epidemic AreaNot yet recruitingNCT03101111Phase 2
7Chikungunya Virus Vaccine Trial in Healthy AdultsCompletedNCT01489358Phase 1
8Phase I Trial of Measles Vectored Chikungungya VaccineNot yet recruitingNCT03028441Phase 1
9Seroprevalence of Chikungunya at the End of the First Chikungunya Outbreak in the French Antilles Within a Sample of Patients Treated for a HIV InfectionCompletedNCT02553369
10tDCS and Its Therapeutic Effects in CK FeverCompletedNCT02993952
11A Prospective, Open Label, Treatment Use Study of Patient Safety Following Transfusion of INTERCEPT Platelet ComponentsCompletedNCT02305732
12Pilot Survey of Dengue Fever in Solomon IslandsCompletedNCT01868399
13Causes of Acute Undifferentiated Fever in Outpatients in the Democratic Republic of CongoCompletedNCT02656862
14Zika and Microcephaly: Case-control StudyCompletedNCT02741882
15RT-PCR on Urine Samples: Added Value for the Diagnosis of Chikungunya Virus InfectionRecruitingNCT02714985
16The Pilot Study of Chikungunya Virus Infections in Southern TaiwanRecruitingNCT02174341
17Impact of the Chikungunya Outbreak in Reunion Island on the Quality of Life After 10 YearsRecruitingNCT02901509
18The Evaluation of Potential Zika, Chikungunya, and Dengue Infections in MexicoRecruitingNCT02831699
19Zika Virus and Related Arbovirus Infections in Deferred Blood Donors (ZVADD)RecruitingNCT02794181
20Cohort of Patients Infected by an ArbovirusRecruitingNCT01099852
21A Pilot Study Examining for the Presence of Fecal Coliforms and Tropical Diseases in PeruRecruitingNCT03078894
22Estimated Cumulative Incidence of Zika Infection at the End of the First Epidemic in the French West Indies in a Sample of Patients Followed for HIV Infection.RecruitingNCT03161444
23Study of the Prognostic Value of Musculoskeletal Ultrasound in Adults With ChikungunyaActive, not recruitingNCT02281123
24Effects of Auriculotherapy on Pain and Functional Capacity of Individuals With Chikungunya FeverActive, not recruitingNCT03090685
25Efficacy of Starting Methotrexate Early in Chikungunya ArthritisActive, not recruitingNCT03058471
26Chikungunya Arthritis in the AmericasNot yet recruitingNCT02463968
27Applying Wolbachia to Eliminate DengueNot yet recruitingNCT03055585
28Study on the Persistence of Zika Virus (ZIKV) in Body Fluids of Patients With ZIKV Infection in BrazilNot yet recruitingNCT03106714

Search NIH Clinical Center for Chikungunya

Genetic Tests for Chikungunya

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Anatomical Context for Chikungunya

About this section

MalaCards organs/tissues related to Chikungunya:

36
Testes, Heart, Monocytes, T cells, Bone, Salivary gland, Brain

FMA organs/tissues related to Chikungunya:

17
Joint

Publications for Chikungunya

About this section

Articles related to Chikungunya:

(show top 50)    (show all 654)
idTitleAuthorsYear
1
Epidemiology of Chikungunya Virus Outbreaks in Guadeloupe and Martinique, 2014: An Observational Study in Volunteer Blood Donors. (28081120)
2017
2
Toxicity of ar-curcumene and epi-I^-bisabolol from Hedychium larsenii (Zingiberaceae) essential oil on malaria, chikungunya and St. Louis encephalitis mosquito vectors. (27918946)
2017
3
Regulation of Viral Replication, Apoptosis and Pro-Inflammatory Responses by 17-AAG during Chikungunya Virus Infection in Macrophages. (28067803)
2017
4
Spectral characterisation, antiviral activities, in silico ADMET and molecular docking of the compounds isolated from Tectona grandis to chikungunya virus. (28063412)
2017
5
Do Two Screening Tools for Chikungunya Virus Infection that were Developed among Younger Population Work Equally as Well in Patients Aged over 65 Years? (28056031)
2017
6
Impaired NK cell functionality and increased TNF-I+ production as biomarkers of chronic chikungunya arthritis and rheumatoid arthritis. (28213049)
2017
7
Epidemic outbreak of Chikungunya in two neighboring towns in the Colombian Caribbean: a survival analysis. (28074128)
2017
8
Chikungunya, Influenza, Nipah, and Semliki Forest Chimeric Viruses with Vesicular Stomatitis Virus: Actions in the Brain. (28077641)
2017
9
Chikungunya Infection in Hospitalized Febrile Infants Younger Than 3 Months of Age. (28060043)
2017
10
Glutathionylation of chikungunya nsP2 protein affects protease activity. (27984114)
2017
11
Resolution of a Chikungunya Outbreak in a Prospective Cohort, Cebu, Philippines, 2012-2014. (27649081)
2016
12
High yield expression and purification of Chikungunya virus E2 recombinant protein and its evaluation for serodiagnosis. (27180040)
2016
13
Activities of proteasome and m-calpain are essential for Chikungunya virus replication. (27206501)
2016
14
Chikungunya fever outbreak in Rio de Janeiro, Brazil: Ultrasonographic aspects of musculoskeletal complications. (27619412)
2016
15
Western Blot Detection of Human Anti-Chikungunya Virus Antibody with Recombinant Envelope 2 Protein. (27180586)
2016
16
Structure-function relationship of Chikungunya nsP2 protease: A comparative study with papain. (28054451)
2016
17
Suramin is a potent inhibitor of Chikungunya and Ebola virus cell entry. (27581733)
2016
18
Simultaneous detection of Zika, Chikungunya and Dengue viruses by a multiplex real-time RT-PCR assay. (27614319)
2016
19
Comprehensive Genome-Scale Phylogenetic Study Provides New Insights on the Global Expansion of Chikungunya Virus. (27654297)
2016
20
Chikungunya Virus Infection Manifesting as Intermediate Uveitis. (28010143)
2016
21
Chikungunya Fever With Seizures, Myocarditis, and Severe Thrombocytopenia in a Child With Osteosarcoma. (27128980)
2016
22
Pharmacologic management of pain in patients with Chikungunya: a guideline. (28001212)
2016
23
Molecular Characterisation of Clinical Isolates of Chikungunya Virus: A Study from Tertiary Care Hospitals in Southern India. (27134872)
2016
24
Mathematical Model of Three Age-Structured Transmission Dynamics of Chikungunya Virus. (27190548)
2016
25
Chikungunya Virus Disease: An Emerging Challenge for the Rheumatologist. (27219309)
2016
26
Reduced Incidence of Chikungunya Virus Infection in Communities with Ongoing Aedes Aegypti Mosquito Trap Intervention Studies - Salinas and Guayama, Puerto Rico, November 2015-February 2016. (27171600)
2016
27
Sequential Chikungunya and Zika Virus Infections in a Traveler from Honduras. (27601517)
2016
28
A chikungunya fever vaccine utilizing an insect-specific virus platform. (27991917)
2016
29
Effect of Holding Conditions on the Detection of Chikungunya and Venezuelan Equine Encephalitis Viruses in Mosquito Pools. (27105216)
2016
30
A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs. (27177310)
2016
31
Imported Chikungunya fever case in Greece in June 2014 and public health response. (27159571)
2016
32
Chikungunya virus-associated encephalitis: A cohort study on La RAcunion Island, 2005-2009. (27217467)
2016
33
Chikungunya Fever Cases Identified in the Veterans Health Administration System, 2014. (27144588)
2016
34
Early clearance of Chikungunya virus in children is associated with a strong innate immune response. (27180811)
2016
35
Leukemoid Reaction in Chikungunya Fever. (27437276)
2016
36
Chikungunya and Coronary Artery Bypass Graft Surgery. (28082029)
2016
37
Carpal Tunnel Syndrome after Chikungunya Infection. (27989767)
2016
38
Antiviral activity of the combination of interferon and ribavirin against chikungunya virus: are the results conclusive? (28003356)
2016
39
Febrile or Exanthematous Illness Associated with Zika, Dengue, and Chikungunya Viruses, Panama. (27139219)
2016
40
Chikungunya virus infections among travellers returning to Spain, 2008 to 2014. (27631156)
2016
41
Fatal leptospirosis and chikungunya co-infection: Do not forget leptospirosis during chikungunya outbreaks. (27413690)
2016
42
A comparison of compliance rates with anti-vectorial protective measures during travel to regions with dengue or chikungunya activity, and regions endemic for Plasmodium falciparum malaria. (27378367)
2016
43
Characterization of a Chikungunya virus strain isolated from banked patients' sera. (27590311)
2016
44
Inhibition of chikungunya virus by picolinate that targets viral capsid protein. (27614702)
2016
45
Vector Competence of Aedes aegypti and Aedes polynesiensis Populations from French Polynesia for Chikungunya Virus. (27144888)
2016
46
Impact of Autocidal Gravid Ovitraps on Chikungunya Virus Incidence in Aedes aegypti (Diptera: Culicidae) in Areas With and Without Traps. (28031347)
2016
47
Viremia and Clinical Presentation in Nicaraguan Patients Infected with Zika Virus, Chikungunya Virus, and Dengue Virus. (27578819)
2016
48
Erratum: Congenital Chikungunya Virus Infection after an Outbreak in Salvador, Bahia, Brazil. (27635304)
2016
49
Protein kinases C as potential host targets for the inhibition of chikungunya virus replication. (28039020)
2016
50
A case of chikungunya virus disease presenting with remarkable acute arthritis of a previously damaged finger joint. (28001232)
2016

Variations for Chikungunya

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Expression for genes affiliated with Chikungunya

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Search GEO for disease gene expression data for Chikungunya.

Pathways for genes affiliated with Chikungunya

About this section

Pathways related to Chikungunya according to GeneCards Suite gene sharing:

(show all 48)
idSuper pathwaysScoreTop Affiliating Genes
19.8IL1B, IL6
29.7IL6, TNF
39.7IL6, TNF
49.6IL1B, TNF
59.6IL1B, TNF
6
Show member pathways
9.4DDX58, MAVS, OAS1
79.4CCL5, IL1B, IL6
89.3IL1B, IL6, TNF
99.3IL1B, IL6, TNF
109.3IL1B, IL6, TNF
119.3IL1B, IL6, TNF
129.3IL1B, IL6, TNF
139.3IL1B, IL6, TNF
14
Show member pathways
9.3IL1B, IL6, TNF
159.3IL1B, IL6, TNF
169.3IL1B, IL6, TNF
179.3IL1B, IL6, TNF
189.3IL1B, IL6, TNF
199.3IL1B, IL6, TNF
209.3IL1B, IL6, TNF
219.1IL6, MIF, TNF
22
Show member pathways
9.1BST2, DDX58, OAS1, OAS3
239.0CD209, IL6, TNF
248.9CCL5, IL1B, IL6, TNF
25
Show member pathways
8.9CCL5, IL1B, IL6, TNF
268.9CCL5, IL1B, IL6, TNF
278.9CCL5, IL1B, IL6, TNF
288.9CCL5, IL1B, IL6, TNF
298.8CD40LG, IL6, TNF
308.8IL1B, IL6, MIF, TNF
31
Show member pathways
8.8IL1B, IL6, MIF, TNF
328.7CD209, IL1B, IL6, TNF
338.7CD209, IL1B, IL6, TNF
348.6DDX58, MAVS, OAS1, OAS3, TNF
35
Show member pathways
8.5CD40LG, IL1B, IL6, TNF
36
Show member pathways
8.5CD40LG, IL1B, IL6, TNF
378.5CD40LG, IL1B, IL6, TNF
388.4CD40LG, DDX58, IL1B, TNF
39
Show member pathways
8.3CCL5, DDX58, IL1B, IL6, MAVS, TNF
40
Show member pathways
8.3CCL5, DDX58, IL1B, IL6, MAVS, TNF
41
Show member pathways
8.2BST2, IL1B, IL6, OAS1, OAS3, TNF
428.0CCL5, CD40LG, IL1B, IL6, TNF
43
Show member pathways
7.9CD40LG, IL1B, IL6, MIF, TNF
447.3CCL5, CD40LG, DDX58, IL1B, MAVS, OAS1
45
Show member pathways
7.3CCL5, CD209, IL1B, IL6, MAVS, OAS1
46
Show member pathways
6.9CCL5, CD209, DDX58, IL1B, IL6, MAVS
47
Show member pathways
6.4BST2, CCL5, CD40LG, DDX58, IL1B, IL6
48
Show member pathways
5.0BST2, CCL5, CD209, CD40LG, DDX58, IL1B

GO Terms for genes affiliated with Chikungunya

About this section

Cellular components related to Chikungunya according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.0CD209, CD40LG, IL6, TNF
2cell surfaceGO:00099868.2BST2, CD209, CD40LG, MIF, PHB, TNF
3extracellular spaceGO:00056157.3CCL5, CD40LG, IL1B, IL6, MIF, OAS3
4extracellular regionGO:00055767.2CCL5, CD209, CD40LG, IL1B, IL6, MIF

Biological processes related to Chikungunya according to GeneCards Suite gene sharing:

(show all 48)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of defense response to virus by hostGO:000223010.6DDX58, MAVS
2positive regulation of protein import into nucleus, translocationGO:003316010.6IL6, MAVS
3positive regulation of interferon-alpha productionGO:003272710.6DDX58, MAVS
4positive regulation of transcription factor import into nucleusGO:004299310.5DDX58, MAVS
5positive regulation of granulocyte macrophage colony-stimulating factor productionGO:003272510.5DDX58, IL1B
6positive regulation of JAK-STAT cascadeGO:004642710.5CCL5, IL6
7epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.4IL6, TNF
8negative regulation of lipid storageGO:001088810.4IL6, TNF
9positive regulation of chemokine productionGO:003272210.4IL6, TNF
10RIG-I signaling pathwayGO:003952910.4DDX58, MAVS
11negative regulation of lipid catabolic processGO:005099510.3IL1B, TNF
12positive regulation of calcidiol 1-monooxygenase activityGO:006055910.3IL1B, TNF
13positive regulation of chemokine biosynthetic processGO:004508010.3IL1B, TNF
14positive regulation of fever generationGO:003162210.3IL1B, TNF
15positive regulation of heterotypic cell-cell adhesionGO:003411610.3IL1B, TNF
16positive regulation of membrane protein ectodomain proteolysisGO:005104410.3IL1B, TNF
17positive regulation of NF-kappaB import into nucleusGO:004234610.3IL1B, TNF
18regulation of establishment of endothelial barrierGO:190314010.2IL1B, TNF
19regulation of I-kappaB kinase/NF-kappaB signalingGO:004312210.2IL1B, TNF
20positive regulation of chemokine (C-X-C motif) ligand 2 productionGO:200034310.2MIF, TNF
21humoral immune responseGO:000695910.1BST2, IL6, TNF
22sequestering of triglycerideGO:003073010.1IL1B, TNF
23positive regulation of nitric oxide biosynthetic processGO:004542910.0IL1B, IL6, TNF
24cellular response to organic cyclic compoundGO:00714079.9CCL5, IL1B, TNF
25lipopolysaccharide-mediated signaling pathwayGO:00316639.9CCL5, IL1B, TNF
26positive regulation of smooth muscle cell proliferationGO:00486619.9CCL5, IL6, TNF
27positive regulation of peptidyl-serine phosphorylationGO:00331389.8IL6, MIF, TNF
28protein kinase B signalingGO:00434919.8CCL5, IL1B, TNF
29regulation of insulin secretionGO:00507969.7CCL5, IL1B, TNF
30regulation of immunoglobulin secretionGO:00510239.7CD40LG, TNF
31positive regulation of I-kappaB kinase/NF-kappaB signalingGO:00431239.7BST2, IL1B, MAVS, TNF
32positive regulation of interleukin-8 productionGO:00327579.7DDX58, IL1B, MAVS, TNF
33positive regulation of interleukin-6 productionGO:00327559.6DDX58, IL1B, IL6, TNF
34positive regulation of protein phosphorylationGO:00019349.5IL1B, MAVS, MIF, TNF
35type I interferon signaling pathwayGO:00603379.4BST2, OAS1, OAS3
36positive regulation of gene expressionGO:00106289.4DDX58, IL1B, IL6, PHB, TNF
37leukocyte cell-cell adhesionGO:00071599.4CCL5, CD209, CD40LG
38positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.3DDX58, IL1B, IL6, MAVS, TNF
39defense response to virusGO:00516079.3BST2, DDX58, IL6, MAVS, OAS1, OAS3
40positive regulation of T cell proliferationGO:00421029.2CCL5, CD40LG, IL1B, IL6
41positive regulation of ERK1 and ERK2 cascadeGO:00703749.2CCL5, IL6, MIF, PHB, TNF
42positive regulation of NF-kappaB transcription factor activityGO:00510929.1CD40LG, IL1B, IL6, TNF
43negative regulation of viral genome replicationGO:00450719.0BST2, CCL5, MAVS, OAS1, OAS3, TNF
44immune system processGO:00023768.8CD209, DDX58, MAVS, MIF, OAS1, OAS3
45response to virusGO:00096158.7BST2, CCL5, DDX58, OAS1, OAS3, TNF
46innate immune responseGO:00450878.4BST2, CD209, DDX58, MAVS, MIF, OAS1
47inflammatory responseGO:00069548.3CCL5, CD40LG, IL1B, IL6, MIF, TNF
48immune responseGO:00069558.1CCL5, CD40LG, IL1B, IL6, OAS1, OAS3

Molecular functions related to Chikungunya according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
12-5-oligoadenylate synthetase activityGO:000173010.4OAS1, OAS3
2double-stranded RNA bindingGO:00037259.4DDX58, OAS1, OAS3
3cytokine activityGO:00051258.0CCL5, CD40LG, IL1B, IL6, MIF, TNF

Sources for Chikungunya

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
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46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet