Childhood Type Dermatomyositis (JDM) malady

Rare diseases, Neuronal diseases, Nephrological diseases, Respiratory diseases, Bone diseases, Skin diseases, Muscle diseases categories

Summaries for Childhood Type Dermatomyositis

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NIH Rare Diseases:42 Juvenile dermatomyositis has some similarities to adult dermatomyositis and polymyositis. it typically affects children ages 2 to 15 years, with symptoms that include weakness of the muscles close to the trunk of the body, inflammation, edema, muscle pain, fatigue, skin rashes, abdominal pain, fever, and contractures. children with juvenile dermatomyositis may have difficulty swallowing and breathing, and the heart may also be affected.  about 20 to 30 percent of children with juvenile dermatomyositis develop calcium deposits in the soft tissue. affected children may not show higher than normal levels of the muscle enzyme creatine kinase in their blood but have higher than normal levels of other muscle enzymes. last updated: 5/31/2011

MalaCards based summary: Childhood Type Dermatomyositis, also known as juvenile dermatomyositis, is related to arthritis and interstitial lung disease, and has symptoms including chondrocalcinosis, dry skin and skin rash. Affiliated tissues include skin, heart and lung.

Aliases & Classifications for Childhood Type Dermatomyositis

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31LifeMap Discovery®, 9Disease Ontology, 42NIH Rare Diseases, 48Orphanet, 61UMLS, 39NCIt, 56SNOMED-CT, 34MeSH, 27ICD10 via Orphanet, 35MESH via Orphanet, 62UMLS via Orphanet, 26ICD10
See all sources

Childhood Type Dermatomyositis, Aliases & Descriptions:

Name: Childhood Type Dermatomyositis 31 9
Juvenile Dermatomyositis 9 42 48 61
Juvenile Polymyositis 42 48
Dermatomyositis, Childhood Type 61
Childhood Dermatomyositis 9
Juvenile Myositis 42
Juvenile Pm 48
Juvenile Dm 48
Jdm 42
Jpm 42


Characteristics (Orphanet epidemiological data):

juvenile dermatomyositis:
Age of onset: Childhood; Age of death: Normal

External Ids:

Disease Ontology9 DOID:14203
NCIt39 C27576
MeSH34 D003882
ICD10 via Orphanet27 M33.2, M33.0
SNOMED-CT56 1212005, 201446001
MESH via Orphanet35 C538250
UMLS via Orphanet62 C0263666, C2931785
ICD1026 M33.0

Related Diseases for Childhood Type Dermatomyositis

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Graphical network of the top 20 diseases related to Childhood Type Dermatomyositis:

Diseases related to childhood type dermatomyositis

Symptoms for Childhood Type Dermatomyositis

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 48 (show all 44)
  • palpebral edema/periorbital edema
  • dry/squaly skin/exfoliation
  • cutaneous rash
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • telangiectasiae of the skin
  • telangiectasiae of mucosae
  • subcutaneous nodules/lipomas/tumefaction/swelling
  • muscle weakness/flaccidity
  • myalgia/muscular pain
  • abnormal muscle biopsy/muscle enzymes/cpk/ldh/aldolase/creatin phosphokinase
  • periarticular tissue anomaly/extraarticular calcifications
  • autoimmunity/autoimmune reaction/autoantibodies
  • asthenia/fatigue/weakness
  • biological inflammatory syndrome/increased erythrocyte sedimentation rate/crp
  • chronic skin infection/ulcerations/ulcers/cancrum
  • skin photosensitivity
  • follicular/erythematous/edematous papules/milium
  • pruritus/itching
  • telangiectasic erythema/poikiloderma
  • alopecia
  • constipation
  • interstitial/restrictive pneumopathy/restrictive respiratory syndrome
  • vascularitis/vasculitides/arteritis
  • hypotonia
  • contractures/cramps/trismus/tetania/claudication/opisthotonos
  • articular/joint pain/arthralgia
  • arthritis/synovitis/synovial proliferation
  • fever/chilling
  • feeding disorder/dysphagia/swallowing/sucking disorder/esophageal dyskinesia
  • acute abdominal pain/colic
  • gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia
  • lung fibrosis
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • cough
  • abnormal cry/voice/phonation disorder/nasal speech
  • cardiomyopathy/hypertrophic/dilated
  • pericardium anomalies/pericarditis/absence/cysts/pericardial effusion
  • cardiac rhythm disorder/arrhythmia
  • cardiac conduction defect/sinoauricular/heart/auriculoventricular/branch block
  • angor pectoris/myocardial infarction
  • elocution disorders/dysarthria/dysphonia
  • abnormal emg/electromyogram/electropmyography
  • restricted joint mobility/joint stiffness/ankylosis
  • weight loss/loss of appetite/break in weight curve/general health alteration

HPO human phenotypes related to Childhood Type Dermatomyositis:

(show all 36)
id Description Frequency HPO Source Accession
1 chondrocalcinosis hallmark (90%) HP:0000934
2 dry skin hallmark (90%) HP:0000958
3 skin rash hallmark (90%) HP:0000988
4 muscle weakness hallmark (90%) HP:0001324
5 autoimmunity hallmark (90%) HP:0002960
6 myalgia hallmark (90%) HP:0003326
7 periorbital edema hallmark (90%) HP:0100539
8 mucosal telangiectasiae hallmark (90%) HP:0100579
9 teleangiectasia of the skin hallmark (90%) HP:0100585
10 pruritus typical (50%) HP:0000989
11 cutaneous photosensitivity typical (50%) HP:0000992
12 poikiloderma typical (50%) HP:0001029
13 muscular hypotonia typical (50%) HP:0001252
14 arthritis typical (50%) HP:0001369
15 flexion contracture typical (50%) HP:0001371
16 alopecia typical (50%) HP:0001596
17 constipation typical (50%) HP:0002019
18 restrictive lung disease typical (50%) HP:0002091
19 vasculitis typical (50%) HP:0002633
20 arthralgia typical (50%) HP:0002829
21 abnormality of temperature regulation typical (50%) HP:0004370
22 skin ulcer typical (50%) HP:0200042
23 limitation of joint mobility occasional (7.5%) HP:0001376
24 abnormality of the voice occasional (7.5%) HP:0001608
25 hypertrophic cardiomyopathy occasional (7.5%) HP:0001639
26 coronary artery disease occasional (7.5%) HP:0001677
27 abnormality of the pericardium occasional (7.5%) HP:0001697
28 weight loss occasional (7.5%) HP:0001824
29 abdominal pain occasional (7.5%) HP:0002027
30 respiratory insufficiency occasional (7.5%) HP:0002093
31 neurological speech impairment occasional (7.5%) HP:0002167
32 pulmonary fibrosis occasional (7.5%) HP:0002206
33 gastrointestinal hemorrhage occasional (7.5%) HP:0002239
34 emg abnormality occasional (7.5%) HP:0003457
35 feeding difficulties in infancy occasional (7.5%) HP:0008872
36 arrhythmia occasional (7.5%) HP:0011675

Drugs & Therapeutics for Childhood Type Dermatomyositis

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Drug clinical trials:

Search ClinicalTrials for Childhood Type Dermatomyositis

Search NIH Clinical Center for Childhood Type Dermatomyositis

Genetic Tests for Childhood Type Dermatomyositis

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Anatomical Context for Childhood Type Dermatomyositis

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MalaCards organs/tissues related to Childhood Type Dermatomyositis:

Skin, Heart, Lung, Bone

Animal Models for Childhood Type Dermatomyositis or affiliated genes

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Publications for Childhood Type Dermatomyositis

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Variations for Childhood Type Dermatomyositis

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Expression for genes affiliated with Childhood Type Dermatomyositis

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16Gene Expression Omnibus DataSets, 31LifeMap Discovery®
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LifeMap Discovery
Genes differentially expressed in tissues of Childhood Type Dermatomyositis patients vs. healthy controls: 31 (show all 292)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1IFIT3interferon-induced protein with tetratricopeptide repeats 3Skeletal Muscle+5.580.000
2ISG15ISG15 ubiquitin-like modifierSkeletal Muscle+5.250.000
3XISTX inactive specific transcript (non-protein coding)Skeletal Muscle+5.140.000
4RSAD2radical S-adenosyl methionine domain containing 2Skeletal Muscle+4.940.000
5GBP1guanylate binding protein 1, interferon-inducibleSkeletal Muscle+4.880.000
6CMPK2cytidine monophosphate (UMP-CMP) kinase 2, mitochondrialSkeletal Muscle+4.610.000
7IFI44Linterferon-induced protein 44-likeSkeletal Muscle+4.420.000
8MX1myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)Skeletal Muscle+4.400.000
9IFI44interferon-induced protein 44Skeletal Muscle+4.340.000
10IFIT2interferon-induced protein with tetratricopeptide repeats 2Skeletal Muscle+3.960.000
11IFI27interferon, alpha-inducible protein 27Skeletal Muscle+3.860.000
12CXCL11chemokine (C-X-C motif) ligand 11Skeletal Muscle+3.670.000
13RPS4Y1ribosomal protein S4, Y-linked 1Skeletal Muscle-3.570.000
14IFIT1interferon-induced protein with tetratricopeptide repeats 1Skeletal Muscle+3.570.000
15MYH3myosin, heavy chain 3, skeletal muscle, embryonicSkeletal Muscle+3.540.000
16SAMHD1SAM domain and HD domain 1Skeletal Muscle+3.520.000
17XAF1XIAP associated factor 1Skeletal Muscle+3.440.000
18KLHDC7Bkelch domain containing 7BSkeletal Muscle+3.440.000
19IFI6interferon, alpha-inducible protein 6Skeletal Muscle+3.430.000
20IFIH1interferon induced with helicase C domain 1Skeletal Muscle+3.430.000
21PARP12poly (ADP-ribose) polymerase family, member 12Skeletal Muscle+3.410.000
22IFI16interferon, gamma-inducible protein 16Skeletal Muscle+3.400.000
23PLSCR1phospholipid scramblase 1Skeletal Muscle+3.370.000
24STAT1signal transducer and activator of transcription 1, 91kDaSkeletal Muscle+3.370.000
25PSMB8proteasome (prosome, macropain) subunit, beta type, 8Skeletal Muscle+3.350.000
26NNMTnicotinamide N-methyltransferaseSkeletal Muscle+3.310.000
27TRIM22tripartite motif containing 22Skeletal Muscle+3.270.000
28DTX3Ldeltex 3 like, E3 ubiquitin ligaseSkeletal Muscle+3.230.000
29EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 2Skeletal Muscle+3.140.000
30IRF7interferon regulatory factor 7Skeletal Muscle+3.130.000
31OAS12'-5'-oligoadenylate synthetase 1, 40/46kDaSkeletal Muscle+3.090.000
32IFITM1interferon induced transmembrane protein 1Skeletal Muscle+3.060.000
33TNFSF10tumor necrosis factor (ligand) superfamily, member 10Skeletal Muscle+3.050.000
34PARP9poly (ADP-ribose) polymerase family, member 9Skeletal Muscle+3.050.000
35POSTNperiostin, osteoblast specific factorSkeletal Muscle+3.030.000
36LGALS3BPlectin, galactoside-binding, soluble, 3 binding proteinSkeletal Muscle+2.940.000
37HERC5HECT and RLD domain containing E3 ubiquitin protein ligase 5Skeletal Muscle+2.930.000
38EPSTI1epithelial stromal interaction 1 (breast)Skeletal Muscle+2.920.000
39COL1A2collagen, type I, alpha 2Skeletal Muscle+2.920.000
40SAMD9sterile alpha motif domain containing 9Skeletal Muscle+2.920.000
41PARP14poly (ADP-ribose) polymerase family, member 14Skeletal Muscle+2.910.000
42GBP3guanylate binding protein 3Skeletal Muscle+2.900.000
43HERC6HECT and RLD domain containing E3 ubiquitin protein ligase family member 6Skeletal Muscle+2.900.000
44GBP2guanylate binding protein 2, interferon-inducibleSkeletal Muscle+2.900.000
45UBE2L6ubiquitin-conjugating enzyme E2L 6Skeletal Muscle+2.900.000
46CHRNA1cholinergic receptor, nicotinic, alpha 1 (muscle)Skeletal Muscle+2.890.000
47CCL8chemokine (C-C motif) ligand 8Skeletal Muscle+2.830.000
48DLK1delta-like 1 homolog (Drosophila)Skeletal Muscle+2.810.000
49ODF3Bouter dense fiber of sperm tails 3BSkeletal Muscle+2.770.000
50PSMB9proteasome (prosome, macropain) subunit, beta type, 9Skeletal Muscle+2.760.000
51MYH8myosin, heavy chain 8, skeletal muscle, perinatalSkeletal Muscle+2.760.000
52DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 58Skeletal Muscle+2.760.000
53SAT1spermidine/spermine N1-acetyltransferase 1Skeletal Muscle+2.730.000
54NMIN-myc (and STAT) interactorSkeletal Muscle+2.710.000
55COL1A1collagen, type I, alpha 1Skeletal Muscle+2.690.000
56TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)Skeletal Muscle+2.680.000
57RNF213ring finger protein 213Skeletal Muscle+2.640.000
58COL3A1collagen, type III, alpha 1Skeletal Muscle+2.600.000
59TIMP1TIMP metallopeptidase inhibitor 1Skeletal Muscle+2.590.000
60HBBhemoglobin, betaSkeletal Muscle-2.580.000
61TAP2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)Skeletal Muscle+2.580.000
62GCH1GTP cyclohydrolase 1Skeletal Muscle+2.550.000
63C1QCcomplement component 1, q subcomponent, C chainSkeletal Muscle+2.540.000
64IFI35interferon-induced protein 35Skeletal Muscle+2.520.000
65ADARadenosine deaminase, RNA-specificSkeletal Muscle+2.510.000
66MX2myxovirus (influenza virus) resistance 2 (mouse)Skeletal Muscle+2.500.000
67MXRA5matrix-remodelling associated 5Skeletal Muscle+2.490.000
68RARRES3retinoic acid receptor responder (tazarotene induced) 3Skeletal Muscle+2.470.000
69ASPNasporinSkeletal Muscle+2.450.000
70CALCBcalcitonin-related polypeptide betaSkeletal Muscle+2.430.000
71RAPH1Ras association (RalGDS/AF-6) and pleckstrin homology domains 1Skeletal Muscle+2.420.000
72OAS32'-5'-oligoadenylate synthetase 3, 100kDaSkeletal Muscle+2.410.000
73SP110SP110 nuclear body proteinSkeletal Muscle+2.410.000
74MLLT11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11Skeletal Muscle+2.390.000
75LUMlumicanSkeletal Muscle+2.370.000
76ARG2arginase 2Skeletal Muscle+2.370.000
77PPM1Kprotein phosphatase, Mg2+/Mn2+ dependent, 1KSkeletal Muscle+2.370.000
78OAS22'-5'-oligoadenylate synthetase 2, 69/71kDaSkeletal Muscle+2.360.000
79SAMD9Lsterile alpha motif domain containing 9-likeSkeletal Muscle+2.350.000
80ASNSasparagine synthetase (glutamine-hydrolyzing)Skeletal Muscle+2.330.000
81CTHRC1collagen triple helix repeat containing 1Skeletal Muscle+2.330.000
82STAT2signal transducer and activator of transcription 2, 113kDaSkeletal Muscle+2.310.000
83BTN3A2butyrophilin, subfamily 3, member A2Skeletal Muscle+2.300.000
84CXCL10chemokine (C-X-C motif) ligand 10Skeletal Muscle+2.300.000
85TNFSF13Btumor necrosis factor (ligand) superfamily, member 13bSkeletal Muscle+2.300.000
86SRPXsushi-repeat containing protein, X-linkedSkeletal Muscle+2.290.000
87MEGF10multiple EGF-like-domains 10Skeletal Muscle+2.280.000
88SP100SP100 nuclear antigenSkeletal Muscle+2.270.000
89DDX60DEAD (Asp-Glu-Ala-Asp) box polypeptide 60Skeletal Muscle+2.270.000
90NCOA7nuclear receptor coactivator 7Skeletal Muscle+2.260.000
91FAM26Ffamily with sequence similarity 26, member FSkeletal Muscle+2.250.000
92MALAT1metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)Skeletal Muscle+2.250.000
93UGCGUDP-glucose ceramide glucosyltransferaseSkeletal Muscle+2.240.000
94C1Scomplement component 1, s subcomponentSkeletal Muscle+2.230.000
95COL5A2collagen, type V, alpha 2Skeletal Muscle+2.230.000
96C1Rcomplement component 1, r subcomponentSkeletal Muscle+2.220.000
97HLA-Fmajor histocompatibility complex, class I, FSkeletal Muscle+2.210.000
98BST2bone marrow stromal cell antigen 2Skeletal Muscle+2.210.000
99OSBPL8oxysterol binding protein-like 8Skeletal Muscle+2.210.000
100IFIT5interferon-induced protein with tetratricopeptide repeats 5Skeletal Muscle+2.210.000
101SRGNserglycinSkeletal Muscle+2.210.000
102DCLK1doublecortin-like kinase 1Skeletal Muscle+2.200.000
103C1QBcomplement component 1, q subcomponent, B chainSkeletal Muscle+2.190.000
104SERPING1serpin peptidase inhibitor, clade G (C1 inhibitor), member 1Skeletal Muscle+2.190.000
105PENKproenkephalinSkeletal Muscle+2.180.000
106CBX4chromobox homolog 4Skeletal Muscle+2.170.000
107IFITM3interferon induced transmembrane protein 3Skeletal Muscle+2.150.000
108LY6Elymphocyte antigen 6 complex, locus ESkeletal Muscle+2.120.000
109FMR1fragile X mental retardation 1Skeletal Muscle+2.110.000
110DUSP6dual specificity phosphatase 6Skeletal Muscle+2.100.000
111TUBB2Atubulin, beta 2A class IIaSkeletal Muscle+2.090.000
112SLC38A1solute carrier family 38, member 1Skeletal Muscle+2.090.000
113GADD45Agrowth arrest and DNA-damage-inducible, alphaSkeletal Muscle+2.080.000
114DDX60LDEAD (Asp-Glu-Ala-Asp) box polypeptide 60-likeSkeletal Muscle+2.080.000
115PDK4pyruvate dehydrogenase kinase, isozyme 4Skeletal Muscle+2.070.000
116BTG1B-cell translocation gene 1, anti-proliferativeSkeletal Muscle+2.060.000
117LAMB1laminin, beta 1Skeletal Muscle+2.040.000
118PLAGL1pleiomorphic adenoma gene-like 1Skeletal Muscle+2.040.000
119CALRcalreticulinSkeletal Muscle+2.040.000
120SYNPO2synaptopodin 2Skeletal Muscle+2.040.000
121H19H19, imprinted maternally expressed transcript (non-protein coding)Skeletal Muscle+2.030.000
122TAF1DTATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDaSkeletal Muscle+2.020.000
123C11orf96chromosome 11 open reading frame 96Skeletal Muscle+2.020.000
124CCDC71Lcoiled-coil domain containing 71-likeSkeletal Muscle+2.020.000
125PHF11PHD finger protein 11Skeletal Muscle+2.010.000
126COL4A2collagen, type IV, alpha 2Skeletal Muscle+2.000.000
127HMGB2high mobility group box 2Skeletal Muscle+2.000.000
128MESTmesoderm specific transcriptSkeletal Muscle+2.000.000
129KIAA0226KIAA0226Skeletal Muscle+2.000.000
130HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Skeletal Muscle+1.970.000
131VCAM1vascular cell adhesion molecule 1Skeletal Muscle+1.960.000
132FGL2fibrinogen-like 2Skeletal Muscle+1.950.000
133C1QAcomplement component 1, q subcomponent, A chainSkeletal Muscle+1.950.000
134CD44CD44 molecule (Indian blood group)Skeletal Muscle+1.950.000
135SMAD1SMAD family member 1Skeletal Muscle+1.950.000
136GIMAP2GTPase, IMAP family member 2Skeletal Muscle+1.940.000
137HLA-Amajor histocompatibility complex, class I, ASkeletal Muscle+1.930.000
138ABI3BPABI family, member 3 (NESH) binding proteinSkeletal Muscle+1.920.000
139NID1nidogen 1Skeletal Muscle+1.920.000
140COL4A1collagen, type IV, alpha 1Skeletal Muscle+1.910.000
141CYLDcylindromatosis (turban tumor syndrome)Skeletal Muscle+1.910.000
142S100A11S100 calcium binding protein A11Skeletal Muscle+1.910.000
143PREPLprolyl endopeptidase-likeSkeletal Muscle+1.890.000
144SH3BGRLSH3 domain binding glutamate-rich protein likeSkeletal Muscle+1.890.000
145CD47CD47 moleculeSkeletal Muscle+1.880.000
146HCP5HLA complex P5 (non-protein coding)Skeletal Muscle+1.880.000
147SOX4SRY (sex determining region Y)-box 4Skeletal Muscle+1.880.000
148TYROBPTYRO protein tyrosine kinase binding proteinSkeletal Muscle+1.880.000
149WARStryptophanyl-tRNA synthetaseSkeletal Muscle+1.880.000
150EFEMP1EGF containing fibulin-like extracellular matrix protein 1Skeletal Muscle+1.880.000
151HLA-Emajor histocompatibility complex, class I, ESkeletal Muscle+1.880.000
152CFHcomplement factor HSkeletal Muscle+1.880.000
153SCO2SCO2 cytochrome c oxidase assembly proteinSkeletal Muscle+1.880.000
154LAP3leucine aminopeptidase 3Skeletal Muscle+1.880.000
155GIMAP7GTPase, IMAP family member 7Skeletal Muscle+1.870.000
156IFITM2interferon induced transmembrane protein 2Skeletal Muscle+1.870.000
157ACTC1actin, alpha, cardiac muscle 1Skeletal Muscle+1.860.000
158GJA1gap junction protein, alpha 1, 43kDaSkeletal Muscle+1.860.000
159ACTR3ARP3 actin-related protein 3 homolog (yeast)Skeletal Muscle+1.860.000
160PPIBpeptidylprolyl isomerase B (cyclophilin B)Skeletal Muscle+1.860.000
161MARCKSmyristoylated alanine-rich protein kinase C substrateSkeletal Muscle+1.850.000
162SLFN5schlafen family member 5Skeletal Muscle+1.850.000
163ZNF655zinc finger protein 655Skeletal Muscle+1.850.000
164ARHGAP36Rho GTPase activating protein 36Skeletal Muscle+1.840.000
165CYR61cysteine-rich, angiogenic inducer, 61Skeletal Muscle+1.830.000
166ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1Skeletal Muscle+1.830.000
167MYOFmyoferlinSkeletal Muscle+1.830.000
168STRNstriatin, calmodulin binding proteinSkeletal Muscle+1.830.000
169TMCC3transmembrane and coiled-coil domain family 3Skeletal Muscle+1.820.000
170TDRD7tudor domain containing 7Skeletal Muscle+1.820.000
171C21orf91chromosome 21 open reading frame 91Skeletal Muscle+1.800.000
172GFPT1glutamine--fructose-6-phosphate transaminase 1Skeletal Muscle+1.800.000
173LRRFIP1leucine rich repeat (in FLII) interacting protein 1Skeletal Muscle+1.780.000
174NIPSNAP3Anipsnap homolog 3A (C. elegans)Skeletal Muscle+1.780.000
175HLA-Gmajor histocompatibility complex, class I, GSkeletal Muscle+1.780.000
176ATP6AP2ATPase, H+ transporting, lysosomal accessory protein 2Skeletal Muscle+1.770.000
177WWTR1WW domain containing transcription regulator 1Skeletal Muscle+1.770.000
178VCANversicanSkeletal Muscle+1.770.000
179MTHFD2methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolaseSkeletal Muscle+1.770.000
180FBP2fructose-1,6-bisphosphatase 2Skeletal Muscle-1.760.000
181HLA-Cmajor histocompatibility complex, class I, CSkeletal Muscle+1.760.000
182CLIC4chloride intracellular channel 4Skeletal Muscle+1.760.000
183SPIN1spindlin 1Skeletal Muscle+1.750.000
184ENPP2ectonucleotide pyrophosphatase/phosphodiesterase 2Skeletal Muscle+1.750.000
185ACTN1actinin, alpha 1Skeletal Muscle+1.750.000
186LIMA1LIM domain and actin binding 1Skeletal Muscle+1.750.000
187TCEAL7transcription elongation factor A (SII)-like 7Skeletal Muscle+1.740.000
188MCAMmelanoma cell adhesion moleculeSkeletal Muscle+1.740.000
189KDM5Dlysine (K)-specific demethylase 5DSkeletal Muscle-1.740.000
190C6orf62chromosome 6 open reading frame 62Skeletal Muscle+1.740.000
191PHLDB2pleckstrin homology-like domain, family B, member 2Skeletal Muscle+1.730.000
192ANKRD10-IT1ANKRD10 intronic transcript 1 (non-protein coding)Skeletal Muscle+1.720.000
193TCF4transcription factor 4Skeletal Muscle+1.720.000
194NRAPnebulin-related anchoring proteinSkeletal Muscle-1.720.000
195BBXbobby sox homolog (Drosophila)Skeletal Muscle+1.720.000
196TUBB6tubulin, beta 6 class VSkeletal Muscle+1.720.000
197XRN15'-3' exoribonuclease 1Skeletal Muscle+1.710.000
198ZFP36L1ZFP36 ring finger protein-like 1Skeletal Muscle+1.700.000
199ANXA1annexin A1Skeletal Muscle+1.700.000
200ANKFY1ankyrin repeat and FYVE domain containing 1Skeletal Muscle+1.690.000
201CD14CD14 moleculeSkeletal Muscle+1.690.000
202PRNPprion proteinSkeletal Muscle+1.690.000
203EIF2S3eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDaSkeletal Muscle+1.690.000
204LINC00844long intergenic non-protein coding RNA 844Skeletal Muscle-1.540.000
205PGAM2phosphoglycerate mutase 2 (muscle)Skeletal Muscle-1.420.000
206RUNX3runt-related transcription factor 3Skeletal Muscle-1.390.000
207PWWP2BPWWP domain containing 2BSkeletal Muscle-1.370.000
208LINC00475long intergenic non-protein coding RNA 475Skeletal Muscle-1.370.000
209PEBP4phosphatidylethanolamine-binding protein 4Skeletal Muscle-1.350.000
210TTTY14testis-specific transcript, Y-linked 14 (non-protein coding)Skeletal Muscle-1.350.000
211ADCK3aarF domain containing kinase 3Skeletal Muscle-1.330.000
212GPR144G protein-coupled receptor 144Skeletal Muscle-1.330.000
213OR7E47Polfactory receptor, family 7, subfamily E, member 47 pseudogeneSkeletal Muscle-1.330.000
214C20orf166chromosome 20 open reading frame 166Skeletal Muscle-1.320.000
215FABP3fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)Skeletal Muscle-1.310.000
216MYBL1v-myb avian myeloblastosis viral oncogene homolog-like 1Skeletal Muscle-1.290.000
217NDRG2NDRG family member 2Skeletal Muscle-1.280.000
218DDX3YDEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linkedSkeletal Muscle-1.270.000
219PIK3CDphosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit deltaSkeletal Muscle-1.260.000
220TNFRSF10Ctumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domainSkeletal Muscle-1.250.000
221GAMTguanidinoacetate N-methyltransferaseSkeletal Muscle-1.250.000
222CYP11B2cytochrome P450, family 11, subfamily B, polypeptide 2Skeletal Muscle-1.240.000
223SAMD4Asterile alpha motif domain containing 4ASkeletal Muscle-1.230.000
224ATP2A2ATPase, Ca++ transporting, cardiac muscle, slow twitch 2Skeletal Muscle-1.200.000
225PRKD2protein kinase D2Skeletal Muscle-1.200.000
226MN1meningioma (disrupted in balanced translocation) 1Skeletal Muscle-1.180.000
227SEPT5septin 5Skeletal Muscle-1.180.000
228SLC25A11solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11Skeletal Muscle-1.180.000
229ACTN3actinin, alpha 3Skeletal Muscle-1.170.000
230BAIAP2L2BAI1-associated protein 2-like 2Skeletal Muscle-1.170.000
231GDE1glycerophosphodiester phosphodiesterase 1Skeletal Muscle-1.170.000
232MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2Skeletal Muscle-1.160.000
233DCBLD2discoidin, CUB and LCCL domain containing 2Skeletal Muscle-1.160.000
234EIF1AYeukaryotic translation initiation factor 1A, Y-linkedSkeletal Muscle-1.160.000
235FHL3four and a half LIM domains 3Skeletal Muscle-1.160.000
236SRCRB4Dscavenger receptor cysteine rich domain containing, group B (4 domains)Skeletal Muscle-1.150.000
237TPD52L3tumor protein D52-like 3Skeletal Muscle-1.150.000
238EPHB4EPH receptor B4Skeletal Muscle-1.140.000
239PTAFRplatelet-activating factor receptorSkeletal Muscle-1.140.000
240COX7Ccytochrome c oxidase subunit VIIcSkeletal Muscle-1.120.000
241MYL10myosin, light chain 10, regulatorySkeletal Muscle-1.120.000
242ACAP1ArfGAP with coiled-coil, ankyrin repeat and PH domains 1Skeletal Muscle-1.120.000
243ADAMTS10ADAM metallopeptidase with thrombospondin type 1 motif, 10Skeletal Muscle-1.120.000
244PDP1pyruvate dehyrogenase phosphatase catalytic subunit 1Skeletal Muscle-1.110.000
245GTPBP2GTP binding protein 2Skeletal Muscle-1.110.000
246S100A1S100 calcium binding protein A1Skeletal Muscle-1.110.000
247ELAVL3ELAV like neuron-specific RNA binding protein 3Skeletal Muscle-1.110.000
248EML2echinoderm microtubule associated protein like 2Skeletal Muscle-1.100.000
249KLK15kallikrein-related peptidase 15Skeletal Muscle-1.100.000
250KMT2E-AS1KMT2E antisense RNA 1 (head to head)Skeletal Muscle-1.090.000
251PTP4A1protein tyrosine phosphatase type IVA, member 1Skeletal Muscle-1.090.000
252ZFPM1zinc finger protein, FOG family member 1Skeletal Muscle-1.080.000
253SLC16A3solute carrier family 16 (monocarboxylate transporter), member 3Skeletal Muscle-1.080.000
254TAB1TGF-beta activated kinase 1/MAP3K7 binding protein 1Skeletal Muscle-1.070.000
255NCOR2nuclear receptor corepressor 2Skeletal Muscle-1.070.000
256IL17REinterleukin 17 receptor ESkeletal Muscle-1.070.000
257ASB2ankyrin repeat and SOCS box containing 2Skeletal Muscle-1.060.000
258PPP1R1Aprotein phosphatase 1, regulatory (inhibitor) subunit 1ASkeletal Muscle-1.060.000
259TRABDTraB domain containingSkeletal Muscle-1.060.000
260ADARB1adenosine deaminase, RNA-specific, B1Skeletal Muscle-1.060.000
261FUT7fucosyltransferase 7 (alpha (1,3) fucosyltransferase)Skeletal Muscle-1.060.000
262TMEM59Ltransmembrane protein 59-likeSkeletal Muscle-1.060.000
263UQCRC2ubiquinol-cytochrome c reductase core protein IISkeletal Muscle-1.060.000
264SLC25A12solute carrier family 25 (aspartate/glutamate carrier), member 12Skeletal Muscle-1.060.000
265CASC15cancer susceptibility candidate 15 (non-protein coding)Skeletal Muscle-1.060.000
266HKDC1hexokinase domain containing 1Skeletal Muscle-1.050.000
267FAM57Bfamily with sequence similarity 57, member BSkeletal Muscle-1.050.000
268DUOXA2dual oxidase maturation factor 2Skeletal Muscle-1.050.000
269PDK2pyruvate dehydrogenase kinase, isozyme 2Skeletal Muscle-1.050.000
270CCDC176coiled-coil domain containing 176Skeletal Muscle-1.050.000
271GGT7gamma-glutamyltransferase 7Skeletal Muscle-1.050.000
272PCYT2phosphate cytidylyltransferase 2, ethanolamineSkeletal Muscle-1.040.000
273SLC39A8solute carrier family 39 (zinc transporter), member 8Skeletal Muscle-1.040.000
274AAMDCadipogenesis associated, Mth938 domain containingSkeletal Muscle-1.040.000
275DUSP3dual specificity phosphatase 3Skeletal Muscle-1.040.000
276IL34interleukin 34Skeletal Muscle-1.040.000
277FOXO4forkhead box O4Skeletal Muscle-1.030.000
278MAP2K2mitogen-activated protein kinase kinase 2Skeletal Muscle-1.030.000
279ZNF688zinc finger protein 688Skeletal Muscle-1.030.000
280IMPA2inositol(myo)-1(or 4)-monophosphatase 2Skeletal Muscle-1.020.000
281ITGB2-AS1ITGB2 antisense RNA 1Skeletal Muscle-1.020.000
282NANOS1nanos homolog 1 (Drosophila)Skeletal Muscle-1.020.000
283LRRC20leucine rich repeat containing 20Skeletal Muscle-1.020.000
284USP9Yubiquitin specific peptidase 9, Y-linkedSkeletal Muscle-1.020.000
285BBC3BCL2 binding component 3Skeletal Muscle-1.020.000
286MAPK12mitogen-activated protein kinase 12Skeletal Muscle-1.020.000
287DLG4discs, large homolog 4 (Drosophila)Skeletal Muscle-1.020.000
288RBBP8NLRBBP8 N-terminal likeSkeletal Muscle-1.010.000
289KIF22kinesin family member 22Skeletal Muscle-1.010.000
290DHRS7Cdehydrogenase/reductase (SDR family) member 7CSkeletal Muscle-1.000.000
291LINC00482long intergenic non-protein coding RNA 482Skeletal Muscle-1.000.000
292USP11ubiquitin specific peptidase 11Skeletal Muscle+1.000.000

Search GEO for disease gene expression data for Childhood Type Dermatomyositis.

Pathways for genes affiliated with Childhood Type Dermatomyositis

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Compounds for genes affiliated with Childhood Type Dermatomyositis

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GO Terms for genes affiliated with Childhood Type Dermatomyositis

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Products for genes affiliated with Childhood Type Dermatomyositis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Childhood Type Dermatomyositis

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27ICD10 via Orphanet
35MESH via Orphanet
47OMIM via Orphanet
57SNOMED-CT via Orphanet
62UMLS via Orphanet