JDM
MCID: CHL028
MIFTS: 31

Childhood Type Dermatomyositis (JDM) malady

Rare diseases, Neuronal diseases, Nephrological diseases, Respiratory diseases, Bone diseases, Skin diseases, Muscle diseases categories

Summaries for Childhood Type Dermatomyositis

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Sources:
44NIH Rare Diseases, 34MalaCards
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NIH Rare Diseases:44 Juvenile dermatomyositis has some similarities to adult dermatomyositis and polymyositis. it typically affects children ages 2 to 15 years, with symptoms that include weakness of the muscles close to the trunk of the body, inflammation, edema, muscle pain, fatigue, skin rashes, abdominal pain, fever, and contractures. children with juvenile dermatomyositis may have difficulty swallowing and breathing, and the heart may also be affected.  about 20 to 30 percent of children with juvenile dermatomyositis develop calcium deposits in the soft tissue. affected children may not show higher than normal levels of the muscle enzyme creatine kinase in their blood but have higher than normal levels of other muscle enzymes. last updated: 5/31/2011

MalaCards: Childhood Type Dermatomyositis, also known as juvenile dermatomyositis, is related to arthritis and myositis, and has symptoms including respiratory distress/dyspnea/respiratory failure/lung volume reduction, lung fibrosis and gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia. Affiliated tissues include skin, heart and lung.

Aliases & Classifications for Childhood Type Dermatomyositis

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Sources:
9Disease Ontology, 44NIH Rare Diseases, 50Orphanet, 63UMLS, 41NCIt, 59SNOMED-CT, 36MeSH, 27ICD10 via Orphanet, 60SNOMED-CT via Orphanet, 64UMLS via Orphanet, 37MESH via Orphanet, 26ICD10
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Classifications:



Characteristics (Orphanet epidemiological data):

50
juvenile dermatomyositis:
Age of onset: Childhood; Age of death: Normal


Aliases & Descriptions:

childhood type dermatomyositis 9
juvenile dermatomyositis 9 44 50 63
juvenile polymyositis 44 50
dermatomyositis, childhood type 63
childhood dermatomyositis 9
juvenile myositis 44
juvenile dm 50
juvenile pm 50
jdm 44
jpm 44


External Ids:

Disease Ontology9 DOID:14203
NCIt41 C27576
MeSH36 D003882
ICD10 via Orphanet27 M33.2, M33.0
SNOMED-CT59 1212005, 201446001
SNOMED-CT via Orphanet60 1212005
UMLS via Orphanet64 C0263666, C2931785
MESH via Orphanet37 C538250
ICD1026 M33.0

Related Diseases for Childhood Type Dermatomyositis

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Childhood Type Dermatomyositis:



Diseases related to childhood type dermatomyositis

Symptoms for Childhood Type Dermatomyositis

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50Orphanet
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Symptoms:

50 (show all 44)
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • lung fibrosis
  • gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia
  • acute abdominal pain/colic
  • feeding disorder/dysphagia/swallowing/sucking disorder/esophageal dyskinesia
  • fever/chilling
  • arthritis/synovitis/synovial proliferation
  • articular/joint pain/arthralgia
  • cough
  • abnormal cry/voice/phonation disorder/nasal speech
  • cardiomyopathy/hypertrophic/dilated
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • restricted joint mobility/joint stiffness/ankylosis
  • abnormal emg/electromyogram/electropmyography
  • elocution disorders/dysarthria/dysphonia
  • angor pectoris/myocardial infarction
  • cardiac conduction defect/sinoauricular/heart/auriculoventricular/branch block
  • cardiac rhythm disorder/arrhythmia
  • pericardium anomalies/pericarditis/absence/cysts/pericardial effusion
  • contractures/cramps/trismus/tetania/claudication/opisthotonos
  • hypotonia
  • periarticular tissue anomaly/extraarticular calcifications
  • abnormal muscle biopsy/muscle enzymes/cpk/ldh/aldolase/creatin phosphokinase
  • myalgia/muscular pain
  • muscle weakness/flaccidity
  • subcutaneous nodules/lipomas/tumefaction/swelling
  • telangiectasiae of mucosae
  • telangiectasiae of the skin
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • cutaneous rash
  • dry/squaly skin/exfoliation
  • autoimmunity/autoimmune reaction/autoantibodies
  • asthenia/fatigue/weakness
  • vascularitis/vasculitides/arteritis
  • interstitial/restrictive pneumopathy/restrictive respiratory syndrome
  • constipation
  • alopecia
  • telangiectasic erythema/poikiloderma
  • pruritus/itching
  • follicular/erythematous/edematous papules/milium
  • skin photosensitivity
  • chronic skin infection/ulcerations/ulcers/cancrum
  • biological inflammatory syndrome/increased erythrocyte sedimentation rate/crp
  • palpebral edema/periorbital edema

Drugs & Therapeutics for Childhood Type Dermatomyositis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Childhood Type Dermatomyositis

Search CenterWatch for Childhood Type Dermatomyositis

Genetic Tests for Childhood Type Dermatomyositis

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Anatomical Context for Childhood Type Dermatomyositis

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34MalaCards
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MalaCards organs/tissues related to Childhood Type Dermatomyositis:

34
Skin, Heart, Lung, Bone

Animal Models for Childhood Type Dermatomyositis or affiliated genes

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Publications for Childhood Type Dermatomyositis

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Variations for Childhood Type Dermatomyositis

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Expression for genes affiliated with Childhood Type Dermatomyositis

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Sources:
16Gene Expression Omnibus DataSets
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Search GEO for disease gene expression data for Childhood Type Dermatomyositis.

Pathways for genes affiliated with Childhood Type Dermatomyositis

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Compounds for genes affiliated with Childhood Type Dermatomyositis

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GO Terms for genes affiliated with Childhood Type Dermatomyositis

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Products for genes affiliated with Childhood Type Dermatomyositis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Childhood Type Dermatomyositis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet