MCID: CHL028
MIFTS: 40

Childhood Type Dermatomyositis malady

Categories: Rare diseases, Neuronal diseases, Nephrological diseases, Respiratory diseases, Bone diseases, Skin diseases, Muscle diseases

Aliases & Classifications for Childhood Type Dermatomyositis

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Sources:
11Disease Ontology, 13DISEASES, 29ICD10, 30ICD10 via Orphanet, 34LifeMap Discovery®, 38MeSH, 39MESH via Orphanet, 44NCIt, 47NIH Rare Diseases, 53Orphanet, 61SNOMED-CT, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Childhood Type Dermatomyositis:

Name: Childhood Type Dermatomyositis 34 11 13
Juvenile Dermatomyositis 11 47 53 67
Dermatomyositis, Childhood Type 67
Childhood Dermatomyositis 11
Juvenile Polymyositis 67
 
Juvenile Myositis 47
Juvenile Dm 53
Jdm 47
Jpm 47

Characteristics:

Orphanet epidemiological data:

53
juvenile dermatomyositis:
Inheritance: Not applicable; Prevalence: 1-9/1000000 (Worldwide); Age of onset: Adolescent,Childhood,Infancy; Age of death: normal life expectancy

Classifications:



External Ids:

Disease Ontology11 DOID:14203
MeSH38 D003882
NCIt44 C27576
Orphanet53 ORPHA93672
SNOMED-CT61 1212005
MESH via Orphanet39 C538250
UMLS via Orphanet68 C0263666, C2931785
ICD10 via Orphanet30 M33.0
ICD1029 M33.0

Summaries for Childhood Type Dermatomyositis

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MalaCards based summary: Childhood Type Dermatomyositis, also known as juvenile dermatomyositis, is related to myositis and histoplasmosis pericarditis, and has symptoms including chondrocalcinosis, dry skin and skin rash. An important gene associated with Childhood Type Dermatomyositis is DMBX1 (Diencephalon/Mesencephalon Homeobox 1). Affiliated tissues include skeletal muscle, skin and bone.

Related Diseases for Childhood Type Dermatomyositis

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Graphical network of diseases related to Childhood Type Dermatomyositis:



Diseases related to childhood type dermatomyositis

Symptoms for Childhood Type Dermatomyositis

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Human phenotypes related to Childhood Type Dermatomyositis:

 63 53 (show all 58)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 chondrocalcinosis63 hallmark (90%) HP:0000934
2 dry skin63 53 hallmark (90%) Very frequent (99-80%) HP:0000958
3 skin rash63 53 hallmark (90%) Very frequent (99-80%) HP:0000988
4 muscle weakness63 53 hallmark (90%) Very frequent (99-80%) HP:0001324
5 autoimmunity63 53 hallmark (90%) Very frequent (99-80%) HP:0002960
6 myalgia63 53 hallmark (90%) Very frequent (99-80%) HP:0003326
7 periorbital edema63 hallmark (90%) HP:0100539
8 mucosal telangiectasiae63 53 hallmark (90%) Very frequent (99-80%) HP:0100579
9 telangiectasia of the skin63 hallmark (90%) HP:0100585
10 pruritus63 53 typical (50%) Frequent (79-30%) HP:0000989
11 cutaneous photosensitivity63 53 typical (50%) Frequent (79-30%) HP:0000992
12 poikiloderma63 53 typical (50%) Frequent (79-30%) HP:0001029
13 muscular hypotonia63 53 typical (50%) Frequent (79-30%) HP:0001252
14 arthritis63 53 typical (50%) Frequent (79-30%) HP:0001369
15 flexion contracture63 typical (50%) HP:0001371
16 alopecia63 53 typical (50%) Frequent (79-30%) HP:0001596
17 constipation63 53 typical (50%) Frequent (79-30%) HP:0002019
18 restrictive ventilatory defect63 typical (50%) HP:0002091
19 vasculitis63 53 typical (50%) Frequent (79-30%) HP:0002633
20 arthralgia63 53 typical (50%) Frequent (79-30%) HP:0002829
21 abnormality of temperature regulation63 typical (50%) HP:0004370
22 skin ulcer63 53 typical (50%) Frequent (79-30%) HP:0200042
23 limitation of joint mobility63 53 occasional (7.5%) Occasional (29-5%) HP:0001376
24 abnormality of the voice63 occasional (7.5%) HP:0001608
25 hypertrophic cardiomyopathy63 occasional (7.5%) HP:0001639
26 coronary artery disease63 occasional (7.5%) HP:0001677
27 abnormality of the pericardium63 occasional (7.5%) HP:0001697
28 weight loss63 53 occasional (7.5%) Occasional (29-5%) HP:0001824
29 abdominal pain63 53 occasional (7.5%) Occasional (29-5%) HP:0002027
30 respiratory insufficiency63 occasional (7.5%) HP:0002093
31 neurological speech impairment63 occasional (7.5%) HP:0002167
32 pulmonary fibrosis63 53 occasional (7.5%) Occasional (29-5%) HP:0002206
33 gastrointestinal hemorrhage63 53 occasional (7.5%) Occasional (29-5%) HP:0002239
34 emg abnormality63 53 occasional (7.5%) Occasional (29-5%) HP:0003457
35 feeding difficulties in infancy63 occasional (7.5%) HP:0008872
36 arrhythmia63 53 occasional (7.5%) Occasional (29-5%) HP:0011675
37 dysarthria53 Occasional (29-5%)
38 hoarse voice53 Occasional (29-5%)
39 dysphonia53 Occasional (29-5%)
40 cardiomyopathy53 Occasional (29-5%)
41 angina pectoris53 Occasional (29-5%)
42 pericarditis53 Occasional (29-5%)
43 fever53 Frequent (79-30%)
44 dysphagia53 Occasional (29-5%)
45 restrictive lung disease53 Frequent (79-30%)
46 dyspnea53 Occasional (29-5%)
47 elevated serum creatine phosphokinase53 Very frequent (99-80%)
48 muscle cramps53 Frequent (79-30%)
49 elevated erythrocyte sedimentation rate53 Very frequent (99-80%)
50 calcinosis53 Very frequent (99-80%)
51 erythema53 Very frequent (99-80%)
52 elevated c-reactive protein level53 Very frequent (99-80%)
53 bundle branch block53 Occasional (29-5%)
54 fatigue53 Very frequent (99-80%)
55 cough53 Occasional (29-5%)
56 palpebral edema53 Very frequent (99-80%)
57 teleangiectasia of the skin53 Very frequent (99-80%)
58 myositis53 Very frequent (99-80%)

Drugs & Therapeutics for Childhood Type Dermatomyositis

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Drugs for Childhood Type Dermatomyositis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 65)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AbataceptapprovedPhase 4192332348-12-610237
Synonyms:
CTLA4-Ig
 
CTLA4-IgG4m
CTLA4Ig
CTLA4IgG4m
2HormonesPhase 4, Phase 3, Phase 2, Phase 113979
3VaccinesPhase 46428
4Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 112778
5Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 112767
6Antirheumatic AgentsPhase 4, Phase 3, Phase 2, Phase 110627
7Immunosuppressive AgentsPhase 4, Phase 3, Phase 2, Phase 112770
8beta-endorphinPhase 4133
9Melanocyte-Stimulating HormonesPhase 4132
10Adrenocorticotropic HormonePhase 4155
11
Methylprednisoloneapproved, vet_approvedPhase 3, Phase 2115383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
12
LevoleucovorinapprovedPhase 371168538-85-2
Synonyms:
(6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid
(6S)-5-formyltetrahydrofolic acid
(6S)-Folinic acid
(6S)-Leucovorin
 
(S)-Leucovorin
Citrovorum factor
L-Folinic acid
Levofolene
Levofolinic acid
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
13
MethotrexateapprovedPhase 3, Phase 215181959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-Methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
14
AlendronateapprovedPhase 2, Phase 3160121268-17-5, 66376-36-12088
Synonyms:
(4-Amino-1-hydroxybutylidene)bisphosphonic acid
(4-Amino-1-hydroxybutylidene)diphosphonic acid
(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid
(4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid)
(4-amino-1-hydroxybutylidene)bisphosphonic acid
121268-17-5 (mono-hydrochloride salt, trihydrate)
1yhm
4-Amino-1-hydroxybutane-1,1-diphosphonate
4-Amino-1-hydroxybutane-1,1-diphosphonic Acid
4-Amino-1-hydroxybutylidene-1,1-bis(phosphonic acid)
4-Amino-1-hydroxybutylidene-1,1-bisphosphonate
4-amino-1-hydroxybutane-1,1-diphosphonic acid
66376-36-1
ABDP
AC1L1CW3
AKOS001015793
ALENDRONATE SODIUM
ALENDRONIC ACID
Acide Alendronique
Acide Alendronique [INN-French]
Acide alendronique
Acide alendronique [INN-French]
Acido Alendronico
Acido Alendronico [INN-Spanish]
Acido alendronico
Acido alendronico [INN-Spanish]
Acidum Alendronicum
Acidum Alendronicum [INN-Latin]
Acidum alendronicum
Acidum alendronicum [INN-Latin]
Adronat
 
Alendronate
Alendronate Sodium
Alendronate sodium hydrate
Alendronic acid
Alendronic acid (INN)
Alendronic acid [INN:BAN]
Alendros
Arendal
BIDD:GT0180
C07752
CHEBI:2567
CHEMBL870
CID2088
D07119
DB00630
Fosamax
Fosamax Plus D
HSCI1_000337
LS-106421
MK 217
MK-217
MolPort-000-421-410
NCGC00096054-01
NCGC00096054-03
NCGC00096054-04
Onclast
Oprea1_422906
Phosphonic acid, (4-amino-1-hydroxybutylidene)bis
SPECTRUM1505166
ST50036159
UNII-X1J18R4W8P
alendronate
bisphosphonate, 65
15
Cyclosporineapproved, investigational, vet_approvedPhase 391579217-60-0, 59865-13-35284373, 6435893
Synonyms:
1c5f
1cyn
30024_FLUKA
30024_SIGMA
59865-13-3
79217-60-0
AC1L1EQW
AC1NQXJE
AC1NR4C4
AC1NUQK3
AC1NUZNC
AC1O5KOG
AC1Q2UDG
Ambap59865-13-3
Ambotz59865-13-3
Antibiotic S 7481F1
BMT-ABA-SAR-MLE-VAL-MLE-ALA-ALA-MLE-MLE-MVA
BMT-ABA-SAR-MLE-VAL-MLE-ALA-DAL-MLE-MLE-MVA
BPBio1_000496
BRD-A64290322-001-01-6
BRD-A69815203-001-04-3
BRD-K13533483-001-03-0
BSPBio_000450
BSPBio_001596
BSPBio_003186
C 3662
C05086
C1832_SIGMA
C3662_SIGMA
C62H111N11O12
CB-01-09 MMX
CHEBI:106343
CHEBI:328305
CHEBI:4031
CHEMBL160
CHEMBL386389
CHEMBL532318
CID2909
CID5280754
CID5284373
CID5458585
CID5497195
CID6435893
CSA
CYCLOSPORIN A (SEE ALSO TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A))
CYCLOSPORIN A, USP
Ciclosporin
Ciclosporin (JP15)
Ciclosporina
Ciclosporine
Ciclosporinum
Cipol N
Cipol-N
Consupren
Consupren S
CsA
CsA & IFN.alpha.
CyA
Cyclokat
Cyclosporin
Cyclosporin A
Cyclosporin A & IFN.alpha.
Cyclosporin A Implant
Cyclosporin A, Tolypocladium inflatum
Cyclosporine (USP)
Cyclosporine A
Cyclosporine [USAN]
D00184
DE-076
DivK1c_000871
EU-0100242
Equoral
GNF-Pf-2808
Gengraf
Gengraf (TN)
HMS1569G12
HMS1791P18
HMS1921L20
HMS1989P18
HMS2089A09
HMS2092F06
HMS502L13
Helv Chim Acta 60: 1568 (1977)
 
I06-0379
I06-0966
IDI1_000871
KBio1_000871
KBio2_000780
KBio2_003348
KBio2_005916
KBio3_002686
KBioGR_001898
KBioSS_000780
LMPK14000003
LS-257
LS-58836
Lopac0_000242
MLS000028376
MLS001333756
MLS002153454
MLS002207033
Mitogard
Modusik-A
MolPort-000-760-988
MolPort-005-934-008
MolPort-006-705-994
NCGC00093704-01
NCGC00093704-02
NCGC00093704-03
NCGC00093704-04
NCGC00093704-05
NCGC00093704-06
NCGC00093704-07
NCGC00093704-08
NCGC00164258-01
NCGC00164258-02
NINDS_000871
NSC290193
Neoplanta
Neoral
Neoral (TN)
NeuroSTAT
Nova-22007
OL 27-400
OL-27400
OLO-400
Papilock
Prestwick2_000435
Prestwick3_000435
Prestwick_731
Pulminiq
Ramihyphin A
Restasis
Restasis (TN)
S-Neoral
S1514_Selleck
SDZ-OXL 400
SMR000058578
SPBio_001467
SPECTRUM1502202
ST-603
Sandimmun
Sandimmun Neoral
Sandimmune
Sandimmune (TN)
Sandimmune, Gengraf, Restasis, Atopica, Sangcya, Cyclosporine
Sang-2000
Sang-35
SangCyA
Sangcya
Sigmasporin
Sigmasporin Microoral
Spectrum2_001484
Spectrum3_001593
Spectrum4_001279
Spectrum5_001628
Spectrum_000300
TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A)
Vekacia
Zyclorin
cyclophorine
cyclosporin A
cyclosporine
from Tolypocladium inflatum (Trichoderma polysporin)
nchembio.184-comp6
nchembio.301-comp5
nchembio.342-comp1
16
Prednisoneapproved, vet_approvedPhase 3, Phase 2135953-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
17
Prednisoloneapproved, vet_approvedPhase 3, Phase 2115350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
18
Miconazoleapproved, investigational, vet_approvedPhase 3362422916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
19
Etanerceptapproved, investigationalPhase 2, Phase 3397185243-69-0
Synonyms:
185243-69-0
CD120b
D00742
Enbrel
Enbrel (TN)
Enbrel Sureclick
Etanercept
Etanercept (USAN/INN)
 
Etanercept (genetical recombination)
Etanercept (genetical recombination) (JAN)
TNF-R2
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B precursor
Tumor necrosis factor receptor type II
etanercept
p75
p80 TNF-alpha receptor
20
Folic Acidapproved, nutraceutical, vet_approvedPhase 3, Phase 2427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
21Prednisolone acetatePhase 3, Phase 21153
22Prednisolone hemisuccinatePhase 3, Phase 21153
23Anti-Infective AgentsPhase 3, Phase 221402
24Peripheral Nervous System AgentsPhase 3, Phase 222776
25Nucleic Acid Synthesis InhibitorsPhase 3, Phase 24855
26Prednisolone phosphatePhase 3, Phase 21153
27Calcineurin InhibitorsPhase 31597
28Bone Density Conservation AgentsPhase 2, Phase 3, Phase 13266
29AntiemeticsPhase 3, Phase 23888
30Vitamin B ComplexPhase 3, Phase 24229
31Neuroprotective AgentsPhase 3, Phase 21672
32Antifungal AgentsPhase 33615
33Protective AgentsPhase 3, Phase 27190
34Autonomic AgentsPhase 3, Phase 29774
35Folic Acid AntagonistsPhase 3, Phase 22200
36Anti-Inflammatory AgentsPhase 3, Phase 210355
37Dermatologic AgentsPhase 3, Phase 25674
38Gastrointestinal AgentsPhase 3, Phase 28109
39glucocorticoidsPhase 3, Phase 2, Phase 14920
40Methylprednisolone HemisuccinatePhase 3, Phase 21153
41Methylprednisolone acetatePhase 3, Phase 21153
42AntimetabolitesPhase 3, Phase 211774
43Antineoplastic Agents, HormonalPhase 3, Phase 25407
44Antimetabolites, AntineoplasticPhase 3, Phase 27171
45AnalgesicsPhase 2, Phase 311287
46Analgesics, Non-NarcoticPhase 2, Phase 36260
47Anti-Inflammatory Agents, Non-SteroidalPhase 2, Phase 34295
48FolateNutraceuticalPhase 3, Phase 24279
49Folinic AcidNutraceuticalPhase 3, Phase 23150
50Vitamin B9NutraceuticalPhase 3, Phase 24279

Interventional clinical trials:

(show all 21)
idNameStatusNCT IDPhase
1Immune Response After Human Papillomavirus Vaccination in Patients With Autoimmune DiseaseUnknown statusNCT00815282Phase 4
2Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic DiseasesUnknown statusNCT01151644Phase 4
3Abatacept in Juvenile DermatomyositisRecruitingNCT02594735Phase 4
4Efficacy and Safety of H.P. Acthar Gel for the Treatment of Refractory Cutaneous Manifestations of DermatomyositisRecruitingNCT02245841Phase 4
5Five-year Actively Controlled Clinical Trial in New Onset Juvenile DermatomyositisUnknown statusNCT00323960Phase 3
6Alendronate Osteoporosis StudyUnknown statusNCT00277251Phase 2, Phase 3
7Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DMCompletedNCT00651040Phase 3
8Understanding the Pathogenesis and Treatment of Childhood Onset DermatomyositisTerminatedNCT00035958Phase 2, Phase 3
9Absorption of Corticosteroids in Children With Juvenile DermatomyositisCompletedNCT00004357Phase 2
10Rituximab for the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)CompletedNCT00106184Phase 2
11Topical Sodium Thiosulfate and Fractional Carbon Dioxide Laser in Treating Dermatomyositis Associated CalcinosisCompletedNCT01572844Phase 2
12Denosumab for Glucocorticoid-treated Children With Rheumatic DisordersNot yet recruitingNCT02418273Phase 1, Phase 2
13Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune DisordersCompletedNCT00010335Phase 1
14Creatine Supplementation in Pediatric RheumatologyUnknown statusNCT01217320
15Studies on Abnormal Bone From Patients With Polyostotic Fibrous Dysplasia and McCune Albright SyndromeCompletedNCT00001973
16The CARRA RegistryCompletedNCT01697254
17Genetic and Family Studies of Inherited Muscle DiseasesCompletedNCT00001331
18The Effect of Creatine Supplementation on Muscle Function in Childhood MyositisRecruitingNCT02267005
19Adult and Juvenile MyositisRecruitingNCT00017914
20Steroid-Induced Osteoporosis in the Pediatric Population - Canadian Incidence StudyActive, not recruitingNCT01663129
21Compassionate Use Protocol for the Treatment of Autoinflammatory SyndromesAvailableNCT01724580

Search NIH Clinical Center for Childhood Type Dermatomyositis

Genetic Tests for Childhood Type Dermatomyositis

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Anatomical Context for Childhood Type Dermatomyositis

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MalaCards organs/tissues related to Childhood Type Dermatomyositis:

35
Skeletal muscle, Skin, Bone, Lung

Animal Models for Childhood Type Dermatomyositis or affiliated genes

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Publications for Childhood Type Dermatomyositis

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Variations for Childhood Type Dermatomyositis

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Expression for genes affiliated with Childhood Type Dermatomyositis

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LifeMap Discovery
Genes differentially expressed in tissues of Childhood Type Dermatomyositis patients vs. healthy controls: 34 (show all 35)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1IFIT3interferon-induced protein with tetratricopeptide repeats 3Skeletal Muscle+5.580.000
2ISG15ISG15 ubiquitin-like modifierSkeletal Muscle+5.250.000
3XISTX inactive specific transcript (non-protein coding)Skeletal Muscle+5.140.000
4RSAD2radical S-adenosyl methionine domain containing 2Skeletal Muscle+4.940.000
5GBP1guanylate binding protein 1, interferon-inducibleSkeletal Muscle+4.880.000
6CMPK2cytidine monophosphate (UMP-CMP) kinase 2, mitochondrialSkeletal Muscle+4.610.000
7IFI44Linterferon-induced protein 44-likeSkeletal Muscle+4.420.000
8MX1MX dynamin-like GTPase 1Skeletal Muscle+4.400.000
9IFI44interferon-induced protein 44Skeletal Muscle+4.340.000
10IFIT2interferon-induced protein with tetratricopeptide repeats 2Skeletal Muscle+3.960.000
11IFI27interferon, alpha-inducible protein 27Skeletal Muscle+3.860.000
12CXCL11chemokine (C-X-C motif) ligand 11Skeletal Muscle+3.670.000
13RPS4Y1ribosomal protein S4, Y-linked 1Skeletal Muscle-3.570.000
14IFIT1interferon-induced protein with tetratricopeptide repeats 1Skeletal Muscle+3.570.000
15MYH3myosin, heavy chain 3, skeletal muscle, embryonicSkeletal Muscle+3.540.000
16SAMHD1SAM domain and HD domain 1Skeletal Muscle+3.520.000
17XAF1XIAP associated factor 1Skeletal Muscle+3.440.000
18KLHDC7Bkelch domain containing 7BSkeletal Muscle+3.440.000
19IFI6interferon, alpha-inducible protein 6Skeletal Muscle+3.430.000
20IFIH1interferon induced with helicase C domain 1Skeletal Muscle+3.430.000
21PARP12poly (ADP-ribose) polymerase family, member 12Skeletal Muscle+3.410.000
22IFI16interferon, gamma-inducible protein 16Skeletal Muscle+3.400.000
23PLSCR1phospholipid scramblase 1Skeletal Muscle+3.370.000
24STAT1signal transducer and activator of transcription 1, 91kDaSkeletal Muscle+3.370.000
25PSMB8proteasome subunit beta 8Skeletal Muscle+3.350.000
26NNMTnicotinamide N-methyltransferaseSkeletal Muscle+3.310.000
27TRIM22tripartite motif containing 22Skeletal Muscle+3.270.000
28DTX3Ldeltex 3 like, E3 ubiquitin ligaseSkeletal Muscle+3.230.000
29EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 2Skeletal Muscle+3.140.000
30IRF7interferon regulatory factor 7Skeletal Muscle+3.130.000
31OAS12'-5'-oligoadenylate synthetase 1, 40/46kDaSkeletal Muscle+3.090.000
32IFITM1interferon induced transmembrane protein 1Skeletal Muscle+3.060.000
33TNFSF10tumor necrosis factor (ligand) superfamily, member 10Skeletal Muscle+3.050.000
34PARP9poly (ADP-ribose) polymerase family, member 9Skeletal Muscle+3.050.000
35POSTNperiostin, osteoblast specific factorSkeletal Muscle+3.030.000

Search GEO for disease gene expression data for Childhood Type Dermatomyositis.

Pathways for genes affiliated with Childhood Type Dermatomyositis

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GO Terms for genes affiliated with Childhood Type Dermatomyositis

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Biological processes related to Childhood Type Dermatomyositis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1interferon-gamma-mediated signaling pathwayGO:00603339.3HLA-DQA1, TRIM21

Sources for Childhood Type Dermatomyositis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet