JDM
MCID: CHL028
MIFTS: 31

Childhood Type Dermatomyositis (JDM) malady

Rare diseases, Neuronal diseases, Nephrological diseases, Respiratory diseases, Bone diseases, Skin diseases, Muscle diseases categories
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Summaries for Childhood Type Dermatomyositis

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Sources:
43NIH Rare Diseases, 33MalaCards
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NIH Rare Diseases:43 Juvenile dermatomyositis has some similarities to adult dermatomyositis and polymyositis. it typically affects children ages 2 to 15 years, with symptoms that include weakness of the muscles close to the trunk of the body, inflammation, edema, muscle pain, fatigue, skin rashes, abdominal pain, fever, and contractures. children with juvenile dermatomyositis may have difficulty swallowing and breathing, and the heart may also be affected.  about 20 to 30 percent of children with juvenile dermatomyositis develop calcium deposits in the soft tissue. affected children may not show higher than normal levels of the muscle enzyme creatine kinase in their blood but have higher than normal levels of other muscle enzymes. last updated: 5/31/2011

MalaCards: Childhood Type Dermatomyositis, also known as juvenile dermatomyositis, is related to arthritis and myositis, and has symptoms including respiratory distress/dyspnea/respiratory failure/lung volume reduction, lung fibrosis and gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia. Affiliated tissues include skin, heart and lung.

Aliases & Classifications for Childhood Type Dermatomyositis

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Sources:
8Disease Ontology, 43NIH Rare Diseases, 49Orphanet, 62UMLS, 40NCIt, 58SNOMED-CT, 35MeSH, 26ICD10 via Orphanet, 59SNOMED-CT via Orphanet, 63UMLS via Orphanet, 36MESH via Orphanet, 25ICD10
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Classifications:



Characteristics (Orphanet epidemiological data):

49
juvenile dermatomyositis:
Age of onset: Childhood; Age of death: Normal


Aliases & Descriptions:

childhood type dermatomyositis 8
juvenile dermatomyositis 8 43 49 62
juvenile polymyositis 43 49
dermatomyositis, childhood type 62
childhood dermatomyositis 8
juvenile myositis 43
juvenile dm 49
juvenile pm 49
jdm 43
jpm 43


External Ids:

Disease Ontology8 DOID:14203
NCIt40 C27576
MeSH35 D003882
ICD10 via Orphanet26 M33.2, M33.0
SNOMED-CT58 1212005, 201446001
SNOMED-CT via Orphanet59 1212005
UMLS via Orphanet63 C0263666, C2931785
MESH via Orphanet36 C538250
ICD1025 M33.0

Related Diseases for Childhood Type Dermatomyositis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Childhood Type Dermatomyositis:



Diseases related to childhood type dermatomyositis

Symptoms for Childhood Type Dermatomyositis

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Sources:
49Orphanet
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Symptoms:

49 (show all 44)
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • lung fibrosis
  • gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia
  • acute abdominal pain/colic
  • feeding disorder/dysphagia/swallowing/sucking disorder/esophageal dyskinesia
  • fever/chilling
  • arthritis/synovitis/synovial proliferation
  • articular/joint pain/arthralgia
  • cough
  • abnormal cry/voice/phonation disorder/nasal speech
  • cardiomyopathy/hypertrophic/dilated
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • restricted joint mobility/joint stiffness/ankylosis
  • abnormal emg/electromyogram/electropmyography
  • elocution disorders/dysarthria/dysphonia
  • angor pectoris/myocardial infarction
  • cardiac conduction defect/sinoauricular/heart/auriculoventricular/branch block
  • cardiac rhythm disorder/arrhythmia
  • pericardium anomalies/pericarditis/absence/cysts/pericardial effusion
  • contractures/cramps/trismus/tetania/claudication/opisthotonos
  • hypotonia
  • periarticular tissue anomaly/extraarticular calcifications
  • abnormal muscle biopsy/muscle enzymes/cpk/ldh/aldolase/creatin phosphokinase
  • myalgia/muscular pain
  • muscle weakness/flaccidity
  • subcutaneous nodules/lipomas/tumefaction/swelling
  • telangiectasiae of mucosae
  • telangiectasiae of the skin
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • cutaneous rash
  • dry/squaly skin/exfoliation
  • autoimmunity/autoimmune reaction/autoantibodies
  • asthenia/fatigue/weakness
  • vascularitis/vasculitides/arteritis
  • interstitial/restrictive pneumopathy/restrictive respiratory syndrome
  • constipation
  • alopecia
  • telangiectasic erythema/poikiloderma
  • pruritus/itching
  • follicular/erythematous/edematous papules/milium
  • skin photosensitivity
  • chronic skin infection/ulcerations/ulcers/cancrum
  • biological inflammatory syndrome/increased erythrocyte sedimentation rate/crp
  • palpebral edema/periorbital edema

Drugs & Therapeutics for Childhood Type Dermatomyositis

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Childhood Type Dermatomyositis

Search NIH Clinical Center for Childhood Type Dermatomyositis

Genetic Tests for Childhood Type Dermatomyositis

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Anatomical Context for Childhood Type Dermatomyositis

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33MalaCards
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MalaCards organs/tissues related to Childhood Type Dermatomyositis:

33
Skin, Heart, Lung, Bone

Animal Models for Childhood Type Dermatomyositis or affiliated genes

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Publications for Childhood Type Dermatomyositis

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Variations for Childhood Type Dermatomyositis

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Expression for genes affiliated with Childhood Type Dermatomyositis

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Sources:
15Gene Expression Omnibus DataSets
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Search GEO for disease gene expression data for Childhood Type Dermatomyositis.

Pathways for genes affiliated with Childhood Type Dermatomyositis

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Compounds for genes affiliated with Childhood Type Dermatomyositis

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GO Terms for genes affiliated with Childhood Type Dermatomyositis

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Products for genes affiliated with Childhood Type Dermatomyositis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Childhood Type Dermatomyositis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet