MCID: CHL052
MIFTS: 41

Choledochal Cyst malady

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Choledochal Cyst

Aliases & Descriptions for Choledochal Cyst:

Name: Choledochal Cyst 12 56 42 14 69
Congenital Cystic Dilatation of the Biliary Tract 56
Congenital Choledochal Cyst 12

Classifications:



External Ids:

Disease Ontology 12 DOID:899
ICD10 33 Q44.4
MeSH 42 D015529
NCIt 47 C2943
Orphanet 56 ORPHA480501
UMLS 69 C0008340

Summaries for Choledochal Cyst

MalaCards based summary : Choledochal Cyst, also known as congenital cystic dilatation of the biliary tract, is related to bile duct cysts and cholangiocarcinoma, susceptibility to. An important gene associated with Choledochal Cyst is SST (Somatostatin), and among its related pathways/superpathways are Pathways in cancer and Colorectal Cancer Metastasis. The drugs Midazolam and Hydrocortisone have been mentioned in the context of this disorder. Affiliated tissues include pancreas, liver and colon, and related phenotypes are craniofacial and digestive/alimentary

Wikipedia : 71 Choledochal cysts (a.k.a. bile duct cyst) are congenital conditions involving cystic dilatation of bile... more...

Related Diseases for Choledochal Cyst

Diseases related to Choledochal Cyst via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 92)
id Related Disease Score Top Affiliating Genes
1 bile duct cysts 11.6
2 cholangiocarcinoma, susceptibility to 11.0
3 pancreatitis 10.5
4 hepatitis 10.3
5 biliary atresia 10.3
6 kleptomania 10.2 MMP1 MMP2
7 noonan syndrome 4 10.2 MMP1 MMP2
8 senile atrophy of choroid 10.2 MMP1 MMP2
9 angiomyoma 10.2 MMP1 MMP2
10 linear porokeratosis 10.2 MMP1 MMP2
11 adult neuronal ceroid lipofuscinosis 10.2 MMP1 MMP2
12 onychocytic matricoma 10.2 MMP1 MMP2
13 zika fever 10.1 MMP1 MMP2
14 laryngostenosis 10.1 MMP1 MMP2
15 angelucci's syndrome 10.1 PKHD1 SST
16 subglottis neoplasm 10.1 MMP1 MMP2
17 inclusion body myopathy with paget disease of bone and frontotemporal dementia 10.1 PKHD1 WDR19
18 algoneurodystrophy 10.1 MMP1 MMP2
19 nephronophthisis 4 10.1 TMEM67 WDR19
20 duodenitis 10.1
21 nodular cutaneous amyloidosis 10.1 MMP1 MMP2
22 dicer1-related disorders 10.1 PKHD1 TMEM67
23 breast abscess 10.1 MMP1 MMP2
24 capillary hemangioma 10.1 PKHD1 SST
25 acute pancreatitis 10.1
26 rhabdomyosarcoma 10.1
27 thymus adenosquamous carcinoma 10.1 MMP1 MMP2 SST
28 chronic venous insufficiency 10.1 KRAS SST
29 obstructive jaundice 10.0
30 adenocarcinoma 10.0
31 pelvic inflammatory disease 10.0 KRAS SST
32 large cell neuroendocrine carcinoma 10.0 KRAS SST
33 striated muscle rhabdoid tumor 10.0 KRAS MMP2
34 tabes dorsalis 10.0 KRAS SST
35 neuroretinitis 10.0 KRAS SST
36 portal hypertension 10.0
37 biliary papillomatosis 10.0
38 joubert syndrome 4 10.0 TMEM67 WDR19
39 duodenal atresia 10.0
40 traumatic brain injury 9.9 MMP1 MMP2
41 dental caries 9.9 KRAS MMP2
42 colonic atresia 9.9
43 cholelithiasis 9.9
44 cystadenoma 9.9
45 embryonal rhabdomyosarcoma 9.9
46 duodenal obstruction 9.9
47 intrahepatic cholangiocarcinoma 9.9
48 peritonitis 9.9
49 cholangitis 9.9
50 nasal cavity disease 9.9 KRAS MMP2

Graphical network of the top 20 diseases related to Choledochal Cyst:



Diseases related to Choledochal Cyst

Symptoms & Phenotypes for Choledochal Cyst

MGI Mouse Phenotypes related to Choledochal Cyst:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.56 KRAS MMP2 TMEM67 WDR19
2 digestive/alimentary MP:0005381 9.55 KRAS PKHD1 SST TMEM67 WDR19
3 nervous system MP:0003631 9.43 SST TMEM67 WDR19 KRAS MMP2 PKHD1
4 skeleton MP:0005390 9.02 KRAS MMP2 SST TMEM67 WDR19

Drugs & Therapeutics for Choledochal Cyst

Drugs for Choledochal Cyst (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
2
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754 657311
3
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
4
Etomidate Approved Phase 4 33125-97-2 36339 667484
5
Butyric Acid Experimental Phase 4 107-92-6 264
6 Adjuvants, Anesthesia Phase 4
7 GABA Agents Phase 4
8 GABA Modulators Phase 4
9 Neurotransmitter Agents Phase 4
10 Cortisol succinate Phase 4
11 Tranquilizing Agents Phase 4
12 Anesthetics Phase 4
13 Anesthetics, General Phase 4
14 Anesthetics, Intravenous Phase 4
15 Hydrocortisone 17-butyrate 21-propionate Phase 4
16 Hydrocortisone acetate Phase 4
17 Hydrocortisone-17-butyrate Phase 4
18 Anti-Anxiety Agents Phase 4
19 Hypnotics and Sedatives Phase 4
20 Anti-Inflammatory Agents Phase 4
21 Psychotropic Drugs Phase 4
22 Central Nervous System Depressants Phase 4
23
Pancrelipase Approved 53608-75-6
24 pancreatin
25 Alpha 1-Antitrypsin
26 Protein C Inhibitor
27 Liver Extracts

Interventional clinical trials:


id Name Status NCT ID Phase
1 Effects of Etomidate on Postoperative Circadian Rhythm Changes of Salivary Cortisol in Children Unknown status NCT02013986 Phase 4
2 Cytological Evaluation of Biliary Epithelium After Endoscopic Sphincterotomy Completed NCT01135732
3 Shear Wave Sonoelastography in Pediatric Liver Fibrosis Recruiting NCT02372682
4 UAB HRFD Core Center: Core A: The Hepato/Renal Fibrocystic Diseases Translational Resource Recruiting NCT01401998
5 Clinical and Molecular Investigations Into Ciliopathies Active, not recruiting NCT00068224
6 Superior Bilioenteric Anastomosis by Magnetic Compressive Technique Not yet recruiting NCT02801500

Search NIH Clinical Center for Choledochal Cyst

Cochrane evidence based reviews: choledochal cyst

Genetic Tests for Choledochal Cyst

Anatomical Context for Choledochal Cyst

MalaCards organs/tissues related to Choledochal Cyst:

39
Pancreas, Liver, Colon, Kidney, Testes, Heart, Appendix

Publications for Choledochal Cyst

Articles related to Choledochal Cyst:

(show top 50) (show all 597)
id Title Authors Year
1
Giant Choledochal Cyst in A Neonate. ( 28083508 )
2017
2
Cystic Biliary Atresia and Choledochal Cysts are Distinct Histopathologic Entities. ( 28079575 )
2017
3
Endoscopic Ultrasound Images of a Choledochal Cyst Mimicking a Pregnant Uterus. ( 27924091 )
2016
4
Diagnosis of type IV-A congenital choledochal cyst in a 73-year-old man. ( 27895454 )
2016
5
Todani choledochal cyst type II: case report and review. ( 27813504 )
2016
6
Traumatic Rupture of Choledochal Cyst in Children: Use of Computed Tomography in the Emergency Department. ( 26928097 )
2016
7
Percutaneous Transhepatic Angioplasty for Portal Vein Cavernous Transformation after Choledochal Cyst Surgery. ( 28064268 )
2016
8
Increased survivin expression and its association with clinical parameters of congenital choledochal cysts. ( 27420945 )
2016
9
Significance of imaging modalities for preoperative evaluation of the pancreaticobiliary system in surgery for pediatric choledochal cyst. ( 26994400 )
2016
10
A giant choledochal cyst in infancy: a case report. ( 27279889 )
2016
11
Choledochal cyst Todani IA case report. ( 27769027 )
2016
12
Laparoscopic treatment of congenital choledochal cyst and hepaticojejunostomy with extracorporeal Roux-en-Y anastomosis: technical aspects and early experience with three cases. ( 27345604 )
2016
13
Rupture of a Choledochal Cyst in an Adult Female: A Rare Consequence of Blunt Abdominal Trauma. ( 27647205 )
2016
14
Clinical effects in resection of congenital choledochal cyst of children and jejunum Roux-Y anastomosis by laparoscope. ( 27874945 )
2016
15
Choledochal cyst with an aberrant right cholecysto-hepatic duct draining into cystic duct and a review of literature. ( 27695219 )
2016
16
Type VI Choledochal Cyst-An Unusual Presentation of Jaundice. ( 27867293 )
2016
17
The presentation and management of choledochocele (type III choledochal cyst): A 40-year systematic review of the literature. ( 27829523 )
2016
18
Evaluation of the learning curve of laparoscopic choledochal cyst excision and Roux-en-Y hepaticojejunostomy in children: CUSUM analysis of a single surgeon's experience. ( 27338584 )
2016
19
A variant of type VI choledochal cyst: combined dilatation of cystic duct and common bile duct. ( 26941882 )
2016
20
Gallbladder Volvulus in a Patient with Type I Choledochal Cyst: A Case Report and Review of the Literature. ( 27747125 )
2016
21
Metachronous cholangiocarcinoma 13A years post resection of choledochal cyst-is long-term follow-up useful?: a case study and review of the literature. ( 27307284 )
2016
22
Dilatation of the Proximal Cystic Duct: Is It a Variant to "Type VI" Choledochal Cyst? ( 27504348 )
2016
23
Hepatopancreatoduodenectomy for local recurrence of cholangiocarcinoma after excision of a type IV-A congenital choledochal cyst: a case report. ( 26943695 )
2016
24
Management of Adult Choledochal Cyst Coexisting with Gallbladder Carcinoma: A Case Report and Review of Literature. ( 27013859 )
2016
25
Ciliated Foregut Cyst of the Common Hepatic Duct: An Unusual Mimic of a Type II Choledochal Cyst. ( 27166199 )
2016
26
Treatment of choledochal cyst in a pediatric population. A single institution experience of 15-years. Case series. ( 26900456 )
2016
27
Laparoscopic Treatment of Choledochal Cyst Using Barbed Sutures. ( 27200460 )
2016
28
Laparoscopic management of antenatally detected choledochal cyst: a 10-year review. ( 27129540 )
2016
29
Intracholecystic papillary-tubular neoplasm in a patient with choledochal cyst: a link between choledochal cyst and gallbladder cancer? ( 27480698 )
2016
30
Laparoscopic resection of choledochal cyst with Roux-en-Y hepaticojejunostomy: a case report and review of the literature. ( 27873011 )
2016
31
Cosmetic selection of skin incision for resection of choledochal cyst in young female patients. ( 27621750 )
2016
32
Choledochal Cyst Disease in a Western Center: A 30-Year Experience. ( 27260526 )
2016
33
Laparoscopic choledochal cyst excision and Roux-en-Y hepaticojejunostomy. ( 27436941 )
2016
34
Choledochal cyst: a future indication for peroral choledochoscopy? ( 27852091 )
2016
35
Prenatal diagnosis and prognosis assessment of congenital choledochal cyst in 21 cases. ( 26467207 )
2015
36
Type III choledochal cyst and anomalous pancreatobiliary junction. ( 26432943 )
2015
37
Biliary-enteric reconstruction with hepaticoduodenostomy following laparoscopic excision of choledochal cyst is associated with better postoperative outcomes: a single-centre experience. ( 25433691 )
2015
38
Retrospective assessment of the validity of robotic surgery in comparison to open surgery for pediatric choledochal cyst. ( 25837180 )
2015
39
Usefulness of laparoscopic cholecystostomy in children with complicated choledochal cyst. ( 25676330 )
2015
40
Giant choledochal cyst in infancy--A rare entity. ( 27509715 )
2015
41
Rudimentary Gallbladder Mimicking Choledochal Cyst. ( 26730099 )
2015
42
Choledochal Cyst Mimicking Gallbladder with Stones in a Six-Year-Old with Right-sided Abdominal Pain. ( 26265970 )
2015
43
Giant choledochal cyst. ( 26710482 )
2015
44
Choledochal cyst rupture with an intrahepatic pseudocyst mimicking hepatic mesenchymal hamartoma in an infant. ( 25986162 )
2015
45
Sphincter of Oddi Dysfunction and the Formation of Adult Choledochal Cyst Following Cholecystectomy: A Retrospective Cohort Study. ( 26632721 )
2015
46
Effectiveness of extracorporeal shock wave lithotripsy on intrahepatic biliary calculi developing after choledochal cyst surgery: A case report. ( 26006206 )
2015
47
Choledochal cyst of the cystic duct: Report of imaging findings in three cases and review of literature. ( 26288528 )
2015
48
Unusual Presentations of Choledochal Cyst: Case Series and Review of Literature. ( 27011558 )
2015
49
Comparative analysis of spherical and fusiform choledochal cyst based on three-dimensional magnetic resonance cholangiopancreatography, biliary amylase, and histopathological examination. ( 26166983 )
2015
50
New type of anomalous pancreaticobiliary junction in a patient wA+th choledochal cyst. ( 26081299 )
2015

Variations for Choledochal Cyst

Expression for Choledochal Cyst

Search GEO for disease gene expression data for Choledochal Cyst.

Pathways for Choledochal Cyst

GO Terms for Choledochal Cyst

Cellular components related to Choledochal Cyst according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cilium GO:0005929 8.8 PKHD1 TMEM67 WDR19

Biological processes related to Choledochal Cyst according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 collagen catabolic process GO:0030574 8.96 MMP1 MMP2
2 cilium assembly GO:0060271 8.8 PKHD1 TMEM67 WDR19

Sources for Choledochal Cyst

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....