Aliases & Classifications for Choledocholithiasis

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Choledocholithiasis, Aliases & Descriptions:

Name: Choledocholithiasis 9 11 43 60


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Disease Ontology9 DOID:11755
MeSH33 D042883

Summaries for Choledocholithiasis

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MalaCards based summary: Choledocholithiasis is related to cholecystitis and obstructive jaundice. An important gene associated with Choledocholithiasis is SLC17A5 (solute carrier family 17 (acidic sugar transporter), member 5), and among its related pathways are Selenium Pathway and Fatty acid, triacylglycerol, and ketone body metabolism. The compounds lactulose and glycocholate have been mentioned in the context of this disorder. Affiliated tissues include liver, testes and heart, and related mouse phenotypes are reproductive system and homeostasis/metabolism.

Related Diseases for Choledocholithiasis

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Diseases related to Choledocholithiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 134)
idRelated DiseaseScoreTop Affiliating Genes
1cholecystitis31.1GPT, ELOVL6
2obstructive jaundice30.5ALPP, GGT1
3extrahepatic cholestasis30.5ALPP, GGT1
4cholangiocarcinoma30.4ALPPL2, ALPL, ALPP, GGT1
5cholelithiasis30.2GGT1, ALPP, ALPL, ALPPL2, GUSB, GPT
6intrahepatic cholestasis30.1ABCB4, ALPP, GGT1, SLC17A5
7pancreatitis30.0ABCB4, ALB, ALPPL2, ALPL, ALPP, GGT1
8cholangitis30.0SLC17A5, GGT1, ALPP, ALPL, ALPPL2, ALB
9liver cirrhosis29.8F2, GPT, GUSB, ALB, GGT1, SLC17A5
10hepatitis29.7F2, UGT1A1, GPT, GUSB, ALPP, GGT1
11portal hypertension29.6F2, GPT, ALB, GGT1, SLC17A5
12cholestasis28.9GGT1, ALPP, ALPL, ALPPL2, ALB, GPT
13hepatocellular carcinoma28.5F2, ABCB4, UGT1A1, GPT, ALB, ALPPL2
14gallbladder disease10.6GGT1
15hydrops fetalis10.5GUSB
16hepatitis e10.5GPT
17opisthorchiasis10.5GGT1
18crigler-najjar syndrome, type i10.5UGT1A1
19scrub typhus10.4SLC17A5, GPT
20pyridoxine deficiency10.4GPT, SLC17A5
21neonatal hemochromatosis10.4GGT1, SLC17A5
22cholecystolithiasis10.4
23hellp syndrome10.4GPT, SLC17A5
24neonatal jaundice10.4UGT1A1, GUSB
25acute cholangitis10.3
26cholestasis, progressive familial intrahepatic 110.3GGT1, ABCB4
27alcohol abuse10.3GPT, GGT1, SLC17A5
28hepatitis a10.3F2
29germ cell cancer10.3ALPPL2, ALPP
30endodermal sinus tumor10.3ALPPL2, ALPP
31biliary atresia10.3GGT1, GPT
32hypophosphatasia, infantile10.3ALPP, ALPL
33familial hyperlipidemia10.3GPT, GGT1, SLC17A5
34fascioliasis10.3ALPP, GGT1, SLC17A5
35splenomegaly10.3GPT, SLC17A5
36alcohol dependence10.3GPT, GGT1, SLC17A5
37hypercholesterolemia, familial10.3SLC17A5, GGT1, GPT
38periodontal disease10.3SLC17A5, ALPP, GUSB
39duodenitis10.3
40gonadoblastoma10.3ALPP, ALPPL2
41gingivitis10.2GUSB, ALPP
42dysfibrinogenemia10.2F2
43cholangitis, primary sclerosing10.2ABCB4, GPT, GGT1
44wilson disease10.2GPT, SLC17A5
45rickets10.2ALB, ALPP
46factor vii deficiency10.2F2
47kernicterus10.2ALB, UGT1A1
48marchiafava bignami disease10.2ALPP, ALPL
49hypersplenism10.2F2
50osteitis fibrosa10.2ALPPL2, ALPL, ALPP

Graphical network of the top 20 diseases related to Choledocholithiasis:



Diseases related to choledocholithiasis

Symptoms for Choledocholithiasis

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Drugs & Therapeutics for Choledocholithiasis

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Drug clinical trials:

Search ClinicalTrials for Choledocholithiasis

Search NIH Clinical Center for Choledocholithiasis

Genetic Tests for Choledocholithiasis

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Anatomical Context for Choledocholithiasis

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MalaCards organs/tissues related to Choledocholithiasis:

31
Liver, Testes, Heart

Animal Models for Choledocholithiasis or affiliated genes

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MGI Mouse Phenotypes related to Choledocholithiasis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053898.2F2, ABCB4, GUSB, ALPL, ALPP, GGT1
2MP:00053767.1F2, ABCB4, GUSB, ELOVL6, ALB, ALPL

Publications for Choledocholithiasis

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Articles related to Choledocholithiasis:

(show top 50)    (show all 529)
idTitleAuthorsYear
1
Endoscopic Sphincterotomy Using the Rendezvous Technique for Choledocholithiasis during Laparoscopic Cholecystectomy: A Case Report. (25298761)
2014
2
Magnetic resonance cholangiopancreatography: utilization and usefulness in suspected choledocholithiasis. (25267497)
2014
3
Endoscopic papillary large balloon dilatation alone is safe and effective for the treatment of difficult choledocholithiasis in cases of Billroth II gastrectomy: a single center experience. (23392745)
2013
4
Non-invasive assessment of choledocholithiasis in patients with gallstones and abnormal liver function. (24124333)
2013
5
Consecutive versus separate sessions of endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) for symptomatic choledocholithiasis. (23389062)
2013
6
Successful single-session endosonography-based endoscopic retrograde cholangiopancreatography without fluoroscopy in pregnant patients with suspected choledocholithiasis: a case series. (23798477)
2013
7
Endoscopic papillary balloon dilation for a 7-year-old girl with choledocholithiasis. (23679173)
2013
8
Risk factors of choledocholithiasis formation after liver transplantation. (23558078)
2013
9
Choledocholithiasis presenting with very high transaminase level. (23188856)
2012
10
Endoscopic treatment of difficult choledocholithiasis. (22709458)
2012
11
Relationship of CA 19-9 with choledocholithiasis and cholangitis. (21796554)
2011
12
Endoscopic papillary balloon dilation for removal of choledocholithiasis: indications, advantages, complications, and long-term follow-up results. (21461066)
2011
13
Choledocholithiasis management in rural America: health disparity or health opportunity? (21571311)
2011
14
Laparoscopic exploration of the common bile duct with a rigid scope in patients with problematic choledocholithiasis. (20354699)
2010
15
Successful endoscopic extraction of a large impacted choledocholithiasis in the ampulla of vater: two interesting cases. (20590755)
2010
16
Extraction of surgical clip-induced "lollipop" choledocholithiasis. (20072999)
2010
17
A same day approach for choledocholithiasis using endoscopic stone removal followed by laparoscopic cholecystectomy: a retrospective study. (19260236)
2009
18
Single session versus separate session endoscopic ultrasonography plus endoscopic retrograde cholangiography in patients with low to moderate risk for choledocholithiasis. (19638088)
2009
19
Preoperative diagnosis of choledocholithiasis: the role of MRCP. (19516211)
2009
20
Liver test patterns in patients with acute calculous cholecystitis and/or choledocholithiasis. (19210291)
2009
21
Long-term complications of endoscopic biliary sphincterotomy for choledocholithiasis: a North-American perspective. (19888258)
2009
22
Patients with bulbar papilla and choledocholithiasis and their endoscopic management. (19453023)
2009
23
Management of choledocholithiasis in patients undergoing cholecystectomy. (19566539)
2009
24
Management of preoperatively suspected choledocholithiasis: a decision analysis. (18683008)
2008
25
Laparoendoscopic "rendezvous" versus laparoscopic antegrade sphincterotomy for choledocholithiasis. (18707043)
2008
26
Preoperative clinical and paraclinical predictors of choledocholithiasis. (18522887)
2008
27
Common bile duct thrombi secondary to hepatoma, with biliary invasion mimicking a choledocholithiasis (with video). (17258996)
2007
28
Suspected choledocholithiasis: endoscopic ultrasound or magnetic resonance cholangio-pancreatography? A systematic review. (18049172)
2007
29
Laparoscopic management of difficult recurrent choledocholithiasis. (17651582)
2007
30
Conversion rate for laparoscopic cholecystectomy after endoscopic retrograde cholangiography in the treatment of choledocholithiasis: does the time interval matter? (17031740)
2006
31
Outcomes of cholecystectomy after endoscopic sphincterotomy for choledocholithiasis. (16455464)
2006
32
Role of endoscopic retrograde cholangiopancreatography in the management of suspected choledocholithiasis. (12618941)
2003
33
Cholelithiasis and choledocholithiasis after sequential cytarabine and asparaginase. (12902918)
2003
34
Recurrence of biliary symptoms after endoscopic sphincterectomy for choledocholithiasis in patients with gallbladder stones. (11911095)
2002
35
Diagnosis of choledocholithiasis and bile duct stenosis by magnetic resonance cholangiogram. (11966585)
2002
36
Detection of choledocholithiasis by EUS in acute pancreatitis: a prospective evaluation in 100 consecutive patients. (11522972)
2001
37
Choledocholithiasis in the Setting of Portal Hypertension. (11469971)
2001
38
Over-the-wire US catheter probe as an adjunct to ERCP in the detection of choledocholithiasis. (11726847)
2001
39
Management of choledocholithiasis found during laparoscopic cholecystectomy: a strategy based on the use of postoperative endoscopic retrograde cholangiography and sphincterotomy. (11332046)
2001
40
Choledocholithiasis: endoscopic versus laparoscopic management. (9926747)
1999
41
Eight years' experience with the use of a transcystic common bile duct duodenal double-lumen catheter for the treatment of choledocholithiasis. (9780991)
1998
42
Ofuji's papuloerythroderma following choledocholithiasis with secondary sepsis: complete resolution with surgery. (9692313)
1998
43
Endoscopic ultrasonography for diagnosing choledocholithiasis: a prospective comparative study with ultrasonography and computed tomography. (9040999)
1997
44
Choledocholithiasis and gallstone pancreatitis. (9512804)
1997
45
Biliary stents as temporary treatment for choledocholithiasis in pregnant patients. (9260726)
1997
46
Transduodenal sphincteroplasty in the treatment of choledocholithiasis in pregnancy. (8976069)
1996
47
Endoscopic biliary sphincterotomy and stone extraction in a child with choledocholithiasis complicating Byler's disease. (8985855)
1996
48
Predicting the presence of choledocholithiasis in patients with symptomatic cholelithiasis. (8677945)
1996
49
Choledocholithiasis causing obstructive jaundice 52 years after cholecystectomy. (7594174)
1995
50
Laparoscopic cholecystectomy: laboratory predictors of choledocholithiasis. (7944040)
1994

Variations for Choledocholithiasis

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Expression for genes affiliated with Choledocholithiasis

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Search GEO for disease gene expression data for Choledocholithiasis.

Pathways for genes affiliated with Choledocholithiasis

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Compounds for genes affiliated with Choledocholithiasis

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Compounds related to Choledocholithiasis according to GeneCards Suite gene sharing:

(show top 50)    (show all 229)
idCompoundScoreTop Affiliating Genes
1lactulose4310.0SLC17A5, GUSB, GPT
2glycocholate439.8GUSB, GPT, ABCB4, SLC17A5
3ethyl glucuronide43 2410.8GGT1, UGT1A1, GUSB
4gamma globulin439.7ALB, GGT1, SLC17A5
5hepaplastin439.7F2, GPT, SLC17A5, ALB
6aminopyrine439.6GPT, F2, SLC17A5, GGT1
7glycyrrhizin43 2810.6GPT, GUSB, SLC17A5
8rifampicin43 28 5911.6SLC17A5, GGT1, GPT, UGT1A1
9zidovudine43 49 1211.5SLC17A5, GPT, GUSB, ALB
10mycophenolate mofetil43 49 1211.5GPT, UGT1A1, ALB, GGT1
11uric acid43 2410.4SLC17A5, GGT1, GPT, ALB
127,8-dihydroneopterin43 2410.4ALPPL2, ALPL, ALPP
13dihydroneopterin triphosphate43 2410.3ALPP, ALPPL2, ALPL
14dihydroxyacetone43 2410.3ALPP, ALPL, ALPPL2
15acetaminophen43 2 49 24 1213.3SLC17A5, GPT, UGT1A1, F2, GGT1
16antipyrine43 1210.3GUSB, ALB, GGT1, SLC17A5, F2
17valproic acid43 49 24 1212.3SLC17A5, GGT1, ALB, GPT, UGT1A1
18vitamin b6439.3ALB, ALPP, SLC17A5, ALPL
194-Nitrophenol249.3ALPP, ALPPL2, ALPL
20nash439.3GPT, SLC17A5, GGT1
21Dihydroxyacetone phosphate249.3ALPL, ALPP, ALPPL2
22propylthiouracil43 2 1211.2ALPP, SLC17A5, GGT1
23tacrolimus43 49 1211.2ALB, SLC17A5, GGT1, GPT, ABCB4
24hyaluronic acid43 2410.2SLC17A5, GGT1, ALB, GPT, F2
25pge1439.1GUSB, ALPP, GPT, F2, SLC17A5
26silymarin439.1GUSB, SLC17A5, GGT1, GPT, UGT1A1, F2
27simvastatin43 49 59 28 24 1214.1F2, SLC17A5, ALPP, GPT, UGT1A1
28bezafibrate43 28 1211.1SLC17A5, GPT, ALPP, ABCB4, GGT1
29levamisole43 1210.0ALPPL2, ALPL, ALPP
30verapamil43 28 49 24 1213.0SLC17A5, GGT1, ALPP, GPT, ABCB4
31sevoflurane49 43 1211.0SLC17A5, GPT, ALB, ALPP, GGT1
32isoflurane49 43 1211.0SLC17A5, GPT, ALB, ALPP, GGT1
33phosphorus439.0ALB, SLC17A5, GGT1, ALPP, GPT
34polyethylene glycol439.0SLC17A5, ALPP, ALB, F2
35phenytoin43 49 28 1212.0SLC17A5, UGT1A1, ALB, GGT1, ALPP
36methotrexate49 43 1210.9ALB, SLC17A5, GGT1, F2, ABCB4, GPT
37ethanol43 49 24 1211.8GPT, ALPPL2, ALPL, GGT1, SLC17A5, GUSB
38phenobarbital43 28 49 1211.8GPT, GGT1, ALPP, UGT1A1, GUSB, SLC17A5
39vitamin b12438.7SLC17A5, GGT1, ALB, GUSB, GPT, ALPP
40ursodeoxycholic acid43 24 1210.7GPT, SLC17A5, F2, ABCB4, ALPP, GGT1
41thyroxine43 249.7UGT1A1, GPT, ALB, SLC17A5, GGT1, ALPP
42tamoxifen43 49 28 1211.7ALPP, UGT1A1, F2, SLC17A5, GGT1
43pyridoxal 5-phosphate438.7ALPP, GPT, ALB, GGT1, SLC17A5, ALPL
44heparin43 28 24 1211.5GGT1, ALB, ALPP, GUSB, F2, SLC17A5
45lactate438.4GUSB, GPT, ALB, ALPP, GGT1, SLC17A5
46creatinine438.3ALB, SLC17A5, ALPP, GGT1, F2, GUSB
47cholesterol43 28 24 1211.3GPT, ABCB4, ALB, ALPP, GGT1, SLC17A5
48magnesium43 24 1210.3ALB, SLC17A5, ALPP, ALPL, GPT, ALPPL2
49alanine438.0GPT, UGT1A1, F2, ALB, ABCB4, GGT1
50aspartate437.5GGT1, SLC17A5, F2, UGT1A1, ABCB4, GPT

GO Terms for genes affiliated with Choledocholithiasis

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Cellular components related to Choledocholithiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1anchored component of membraneGO:00312258.7ALPPL2, ALPL, ALPP
2plasma membraneGO:00058867.7F2, ABCB4, ALPPL2, ALPL, ALPP, GGT1

Biological processes related to Choledocholithiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1acute-phase responseGO:00069539.8UGT1A1, F2
2small molecule metabolic processGO:00442817.5GGT1, ALB, ELOVL6, GUSB, GPT, UGT1A1

Molecular functions related to Choledocholithiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1alkaline phosphatase activityGO:00040359.0ALPP, ALPL, ALPPL2

Products for genes affiliated with Choledocholithiasis

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Sources for Choledocholithiasis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet