MCID: CHN004
MIFTS: 41

Chondroblastoma malady

Categories: Rare diseases, Cancer diseases, Bone diseases

Aliases & Classifications for Chondroblastoma

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Aliases & Descriptions for Chondroblastoma:

Name: Chondroblastoma 10 45 47 12 36 65
 
Chondroblastoma of Bone 10

Classifications:



External Ids:

Disease Ontology10 DOID:2649
MeSH36 D002804
NCIt42 C2945
UMLS65 C0008441

Summaries for Chondroblastoma

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Wikipedia:68 Chondroblastoma is a rare, benign, locally aggressive bone tumor that typically affects the epiphyses or... more...

MalaCards based summary: Chondroblastoma, also known as chondroblastoma of bone, is related to hemorrhagic fever and keratoconjunctivitis. An important gene associated with Chondroblastoma is SOX9 (SRY-Box 9), and among its related pathways are Development_Hedgehog and PTH signaling pathways in bone and cartilage development and IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types. Affiliated tissues include bone, breast and brain, and related mouse phenotypes are no phenotypic analysis and endocrine/exocrine gland.

Related Diseases for Chondroblastoma

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Diseases related to Chondroblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 341)
idRelated DiseaseScoreTop Affiliating Genes
1hemorrhagic fever30.3PTGS2, TNFSF11
2keratoconjunctivitis29.9CXCL8, IL5
3diffuse scleroderma29.5CXCL8, IL4, IL5
4rheumatoid arthritis28.7CXCL8, IL2, IL4, PTGS2, TNFSF11
5malaria28.7CXCL8, IL2, IL4, IL5
6blastoma10.4
7kartagener syndrome10.4PTGS2, TNFSF11
8pleomorphic adenoma carcinoma10.3PTGS2, TNFSF11
9goat milk allergy10.3IL4, TNFSF11
10pancreatitis10.3
11kyphoscoliotic heart disease10.2IL4, IL5
12gonococcal bursitis10.2IL4, IL5
13status asthmaticus10.2IL4, IL5
14marcus gunn phenomenon10.2PTHLH, TNFSF11
15benign paroxysmal positional nystagmus10.2IL4, IL5
16superficial urinary bladder cancer10.2IL4, IL5
17eosinophilic gastroenteritis10.2IL4, IL5
18mobitz type ii atrioventricular block10.2IL4, IL5
19granulomatous amebic encephalitis10.2IL4, IL5
20leukemia10.2
21thyroiditis10.2
22celiac trunk compression syndrome10.2CXCL8, PTGS2
23motor peripheral neuropathy10.2IL4, IL5
24hepatitis e10.2IL4, IL5
25immunodeficiency 27b, mycobacteriosis, ad10.2CXCL8, PTGS2
26acantholytic variant squamous cell breast carcinoma10.2IL4, IL5
27ophthalmomyiasis10.2CXCL8, IL4
28prepuce cancer10.1IL4, IL5
29central nervous system childhood germ cell tumor10.1IL5, PTGS2
30eyelid neoplasm10.1CXCL8, PTGS2
31melorheostosis10.1IL4, IL5
32breast cancer10.1
33hepatitis10.1
34lymphoma10.1
35adenocarcinoma10.1
36glioma10.1
37endotheliitis10.1
38hepatoid adenocarcinoma10.1IL4, IL5
39plantar nerve lesion10.1CXCL8, IL5
40gonadal disease10.1CXCL8, PTGS2
41familial hyperlipidemia10.1IL4, IL5
42skeleto cardiac syndrome with thrombocytopenia10.1PTHLH, SOX9
43disseminated eosinophilic collagen disease10.1IL4, IL5
44enamel caries10.1IL4, IL5
45hepatocellular carcinoma10.1
46esophagitis10.1
47cerebritis10.1
48adenoma10.1
49encephalitis10.1
50headache10.1

Graphical network of the top 20 diseases related to Chondroblastoma:



Diseases related to chondroblastoma

Symptoms for Chondroblastoma

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Drugs & Therapeutics for Chondroblastoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Chondroblastoma


Cochrane evidence based reviews: chondroblastoma

Genetic Tests for Chondroblastoma

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Anatomical Context for Chondroblastoma

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MalaCards organs/tissues related to Chondroblastoma:

33
Bone, Breast, Brain, Lung, Testes, Thyroid, Endothelial

Animal Models for Chondroblastoma or affiliated genes

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MGI Mouse Phenotypes related to Chondroblastoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.4IL2, IL4, PTGS2, SOX9, TNFSF11
2MP:00053798.0IL2, IL4, PTGS2, PTHLH, SOX9, TNFSF11
3MP:00053887.7IL2, IL4, IL5, PTGS2, PTHLH, SOX9
4MP:00053817.6IL2, IL4, IL5, PTGS2, PTHLH, SOX9
5MP:00053897.4IL2, IL4, IL5, PTGS2, PTHLH, SOX9
6MP:00053977.1IL2, IL4, IL5, PTGS2, PTHLH, SOX9
7MP:00053876.8IL2, IL4, IL5, PTGS2, PTHLH, SOX9
8MP:00053786.7HK2, IL2, IL4, IL5, PTGS2, PTHLH

Publications for Chondroblastoma

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Articles related to Chondroblastoma:

(show top 50)    (show all 374)
idTitleAuthorsYear
1
Minimal change nephrotic syndrome showing complete remission after resection of a neurofibroma in a type I neurofibromatosis patient. (26951918)
2016
2
Tungiasis Outbreak in Travelers From Madagascar. (26031478)
2015
3
Can an intervention based on a serious videogame prior to cognitive behavioral therapy be helpful in bulimia nervosa? A clinical case study. (26236261)
2015
4
Monostotic fibrous dysplasia of the mandible. (24984642)
2014
5
Comparison of the effect of surgical and medical therapy for the treatment of idiopathic granulomatous mastitis. (25002895)
2014
6
Coexpression of HMGA2 and Oct4 predicts an unfavorable prognosis in human gastric cancer. (25037576)
2014
7
Management of crescentic glomerulonephritis: what are the recent advances? (23689584)
2013
8
Cutaneous candidiasis caused by Candida glabrata in a HIV/AIDS patient. (23970580)
2013
9
BAP1 Immunohistochemistry in a Multi-Institutional Cohort Predicts Outcomes in Patients with Clear Cell Renal Cell Carcinoma. (24076305)
2013
10
Swine influenza virus vaccines: to change or not to change-that's the question. (22976350)
2013
11
Effect of the GLP-1 Analog Exendin-4 and Oxaliplatin on Intrahepatic Cholangiocarcinoma Cell Line and Mouse Model. (24351817)
2013
12
Evolution of gait abnormalities in SOD1(G93A) transgenic mice. (21733494)
2011
13
p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals. (20587414)
2010
14
IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group. (20160062)
2010
15
Expression of long pentraxin PTX3 in human adipose tissue and its relation with cardiovascular risk factors. (18571180)
2009
16
Hsp105beta upregulates hsp70 gene expression through signal transducer and activator of transcription-3. (19754877)
2009
17
Necrotizing fasciitis and myonecrosis "synergistic necrotizing cellulitis" caused by Bacillus cereus. (19583692)
2009
18
Adiponectin stimulates IL-8 production by rheumatoid synovial fibroblasts. (19013427)
2009
19
Transcriptome analysis of nitrogen-efficient rice over-expressing alanine aminotransferase. (19508275)
2009
20
In vivo effect of selective macrophage suppression on the development of intrahepatic cholestasis in mice. (19489305)
2008
21
Ancillary testing of liquid-based cytology specimens for identification of patients at high risk of cervical cancer. (18936966)
2008
22
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene. (17200668)
2007
23
Mononeuropathy following subcutaneous interferon-beta injection. (16511643)
2006
24
Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA. (16177264)
2006
25
Tumor necrosis factor inhibits growth hormone-mediated gene expression in hepatocytes. (16574984)
2006
26
Integrin engagement differentially modulates epithelial cell motility by RhoA/ROCK and PAK1. (15611088)
2005
27
Biological actions of the incretins GIP and GLP-1 and therapeutic perspectives in patients with type 2 diabetes. (16142014)
2005
28
Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus. (14730379)
2004
29
Linear scleroderma en coup de sabre and brain calcification: is there a pathogenic relationship? (12508412)
2003
30
Phagocytosis of serum- and IgG-opsonized zymosan particles induces apoptosis through superoxide but not nitric oxide in macrophage J774A.1. (12858021)
2003
31
Sequence variants of the POMC gene and their associations with body composition in children. (12740451)
2003
32
Emx2 and Pax6 control regionalization of the pre-neuronogenic cortical primordium. (11739261)
2002
33
Critical illness polyneuropathy. (12386490)
2002
34
Expression of the angiogenic growth factors VEGF, FGF-2, EGF and their receptors in normal human endometrium during the menstrual cycle. (11134362)
2001
35
Irritable bowel syndrome. Survey of definitions, differential diagnosis and pathogenesis]. (11475255)
2001
36
X inactivation, DNA deletion, and microsatellite instability in common acquired melanocytic nevi. (11751501)
2001
37
The Sp1 transcription factor regulates cell type-specific transcription of MUC1. (11313016)
2001
38
Mitochondrial toxins in models of neurodegenerative diseases. I: In vivo brain hydroxyl radical production during systemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions. (9313890)
1997
39
Correlation between G1 cyclins and HPV in the uterine cervix. (9421073)
1997
40
Planning and execution of action in children with and without developmental coordination disorder. (9413800)
1997
41
Dysregulation of bcl-2, c-myc, and Fas expression during tricyclic antidepressant-induced apoptosis in human peripheral lymphocytes. (9062851)
1996
42
Unusual visual stimulation in dynamic balance conditions: proposal for a space motion sickness test. (11537946)
1994
43
Experience with buccal phentolamine mesylate for impotence. (7517275)
1994
44
Primary malignant pericardial mesothelioma: a case report and review. (8040178)
1994
45
Long-term phenytoin (Diphedan) therapy leading to IgA nephropathy]. (1614700)
1992
46
Leukotriene B4 stimulates c-fos and c-jun gene transcription and AP-1 binding activity in human monocytes. (1313226)
1992
47
Transport of incoming influenza virus nucleocapsids into the nucleus. (1985199)
1991
48
Polymorphisms of HepG2/erythrocyte glucose-transporter gene. Linkage relationships and implications for genetic analysis of NIDDM. (1976557)
1990
49
Further observations on the structure of a carotid body tumor. (13844973)
1960
50

Variations for Chondroblastoma

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Expression for genes affiliated with Chondroblastoma

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Search GEO for disease gene expression data for Chondroblastoma.

Pathways for genes affiliated with Chondroblastoma

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Pathways related to Chondroblastoma according to GeneCards Suite gene sharing:

(show all 18)
idSuper pathwaysScoreTop Affiliating Genes
19.6PTHLH, TNFSF11
29.5IL4, IL5
39.1CXCL8, PTGS2, TNFSF11
4
Show member pathways
8.7IL2, IL4, IL5
58.7IL2, IL4, IL5
68.7IL2, IL4, IL5
78.7IL2, IL4, IL5
88.7IL2, IL4, IL5
98.7IL2, IL4, IL5
108.7IL2, IL4, IL5
118.6CXCL8, IL2, PTGS2
128.3CXCL8, IL2, IL4, SOX9
138.1CXCL8, IL2, IL4, IL5
14
Show member pathways
8.1CXCL8, IL2, IL4, IL5
15
Show member pathways
7.7CXCL8, IL2, IL4, IL5, TNFSF11
16
Show member pathways
7.6CXCL8, IL2, IL4, IL5, PTGS2
17
Show member pathways
7.3CXCL8, IL2, IL4, IL5, PTGS2, TNFSF11
18
Show member pathways
7.0CXCL8, IL2, IL4, IL5, PTGS2, SOX9

GO Terms for genes affiliated with Chondroblastoma

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Biological processes related to Chondroblastoma according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1regulation of cell adhesionGO:00301559.9CXCL8, SOX9
2positive regulation of T cell differentiationGO:00455829.8IL2, IL4
3extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.8IL2, IL4
4positive regulation of tyrosine phosphorylation of Stat5 proteinGO:00425239.7IL2, IL4
5positive regulation of T cell proliferationGO:00421029.7IL2, IL4
6positive regulation of isotype switching to IgG isotypesGO:00483049.6IL2, IL4
7positive regulation of B cell proliferationGO:00308909.2IL2, IL4, IL5
8positive regulation of protein phosphorylationGO:00019349.1IL2, IL4, SOX9
9positive regulation of transcription from RNA polymerase II promoterGO:00459448.6IL2, IL4, SOX9, TNFSF11
10positive regulation of cell proliferationGO:00082847.8IL2, IL4, IL5, PTHLH, SOX9
11immune responseGO:00069557.7CXCL8, IL2, IL4, IL5, TNFSF11

Sources for Chondroblastoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet