MCID: CHN059
MIFTS: 41

Chondrocalcinosis malady

Categories: Genetic diseases, Bone diseases, Rare diseases

Aliases & Classifications for Chondrocalcinosis

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Aliases & Descriptions for Chondrocalcinosis:

Name: Chondrocalcinosis 39 13
Pseudogout 11 50 68
 
Calcium Pyrophosphate Deposition Disease 11 68

Classifications:



External Ids:

Disease Ontology11 DOID:1156
ICD9CM32 712.1
MeSH39 D002805
NCIt45 C34955

Summaries for Chondrocalcinosis

About this section
Disease Ontology:11 An arthritis that has material basis in the accumulation of salt crystals located in joint.

MalaCards based summary: Chondrocalcinosis, also known as pseudogout, is related to chondrocalcinosis 2 and chondrocalcinosis with early-onset osteoarthritis, and has symptoms including joint stiffness, arthralgia and joint swelling. An important gene associated with Chondrocalcinosis is ANKH (ANKH Inorganic Pyrophosphate Transport Regulator). Affiliated tissues include joint, bone and testes, and related mouse phenotypes are hearing/vestibular/ear and limbs/digits/tail.

Related Diseases for Chondrocalcinosis

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Diseases in the Chondrocalcinosis family:

Chondrocalcinosis 2 Chondrocalcinosis Due to Apatite Crystal Deposition

Diseases related to Chondrocalcinosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 61)
idRelated DiseaseScoreTop Affiliating Genes
1chondrocalcinosis 212.3
2chondrocalcinosis with early-onset osteoarthritis11.9
3chondrocalcinosis due to apatite crystal deposition11.8
4gitelman syndrome11.3
5familial calcium pyrophosphate deposition11.3
6hypocalciuric hypercalcemia, type i10.9
7hypocalciuric hypercalcemia, type ii10.8
8hypocalciuric hypercalcemia, familial, type iii10.8
9kidney cortex necrosis10.2ALPL, ANKH
10hepatic fibrosis renal cysts mental retardation10.2HFE, TNFRSF11B
11hypophosphatasia, adult10.2ALPL, ENPP1
12dystonia 2510.1REN, SLC12A3
13osteoarthritis10.1
14maroteaux stanescu cousin syndrome10.1ALPL, TNFRSF11B
15bartter syndrome, type 310.1REN, SLC12A3
16hypophosphatasia, childhood10.1ALPL, ANKH, ENPP1
17petrositis10.1REN, SLC12A3
18acute frontal sinusitis10.1ALPL, ANKH, ENPP1
19arterial calcification, generalized, of infancy, 210.1ALPL, ANKH, ENPP1
20malignant biphasic mesothelioma10.1REN, SLC12A3
21cranial nerve palsy10.1ANKH, HFE, TNFRSF11B
22pharyngitis10.0ANKH, TNFRSF11B
23hypocalcemia, autosomal dominant10.0CASR, GNA11
24cerebrooculofacioskeletal syndrome 410.0CASR, GNA11
25tumoral calcinosis, hyperphosphatemic, familial10.0
26inflammatory bowel disease 610.0CASR, GNA11
27hyperaldosteronism, familial, type iii9.9CASR, REN
28gout9.9
29arthropathy9.9
30familial chronic myelocytic leukemia-like syndrome9.9CASR, GNA11
31pes anserinus tendinitis or bursitis9.9CASR, TNFRSF11B
32deafness, autosomal recessive 429.9CASR, GNA11
33clear cell adenocarcinoma9.9REN, SLC12A3
34tinea unguium9.9CASR, TNFRSF11B
35bipolar disorder9.9CASR, REN, SLC12A3
36episodic kinesigenic dyskinesia 29.9CASR, REN, SLC12A3
37indian tick typhus9.9CASR, REN, SLC12A3
38high-grade dysplasia in patients with barrett esophagus9.8CASR, REN
39tumoral calcinosis, familial, normophosphatemic9.8
40familial tumoral calcinosis9.8
41arthritis9.8
42hyperostosis9.8
43diffuse idiopathic skeletal hyperostosis9.8
44lung giant cell carcinoma9.7CASR, ENPP1, REN
45craniometaphyseal dysplasia9.6
46brachydactyly9.6
47familial hypocalciuric hypercalcemia9.6
48short bowel syndrome9.6
49nephrocalcinosis9.6
50hyperparathyroidism9.6

Graphical network of the top 20 diseases related to Chondrocalcinosis:



Diseases related to chondrocalcinosis

Symptoms & Phenotypes for Chondrocalcinosis

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UMLS symptoms related to Chondrocalcinosis:


joint stiffness, arthralgia, joint swelling

MGI Mouse Phenotypes related to Chondrocalcinosis according to GeneCards Suite gene sharing:

41 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.8ANKH, ENPP1, GNA11, TNFRSF11B
2MP:00053718.7ALPL, ANKH, GNA11, HFE, MYO10, TNFRSF11B
3MP:00053678.7CASR, ENPP1, GNA11, REN, SLC12A3
4MP:00053858.6ALPL, ANKH, ENPP1, GNA11, REN, SLC12A3
5MP:00053698.4ALPL, ANKH, CASR, ENPP1, GNA11, REN
6MP:00053978.0ALPL, ANKH, CASR, GNA11, HFE, REN
7MP:00053877.7ALPL, ANKH, CASR, ENPP1, GNA11, HFE
8MP:00107687.7ALPL, ANKH, CASR, ENPP1, GNA11, HFE
9MP:00053867.5ALPL, ANKH, CASR, ENPP1, GNA11, HFE
10MP:00053767.2ALPL, ANKH, CASR, ENPP1, GNA11, HFE
11MP:00053907.1ALPL, ANKH, CASR, ENPP1, GNA11, MYO10
12MP:00053787.1ALPL, ANKH, CASR, ENPP1, GNA11, HFE

Drugs & Therapeutics for Chondrocalcinosis

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Drugs for Chondrocalcinosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
ColchicineapprovedPhase 411564-86-86167, 2833
Synonyms:
(S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide
30512-31-3
5843-86-7
64-86-8
7-alpha-H-Colchicine
7.alpha.H-Colchicine
7alphaH-Colchicine
AC1L1LXO
ACon1_000353
AI3-31149
AKOS001582887
BB_NC-0737
BPBio1_000535
BRD-K00259736-001-06-5
BSPBio_000485
BSPBio_002083
Benzo(a)heptalen-9(5H)-one
C 9754
C07592
C22H25NO6
C3915_SIGMA
C9754_SIGMA
CCRIS 691
CHEBI:27882
CHEMBL107
CID6167
CPD-9785
Colchicin
Colchicin [German]
Colchicina
Colchicina [Italian]
Colchicine (JP15/USP)
Colchicine (TN)
Colchicine [JAN]
Colchicine, (+-)-Isomer
Colchicine, (R)-Isomer
Colchicine, Colchicum autumnale
Colchicinum
Colchineos
Colchisol
Colchysat
Colcin
Colcrys
Colsaloid
Colstat
Condylon
D003078
D00570
DB01394
DB08117
DivK1c_000753
EINECS 200-598-5
EU-0100310
Goutnil
HMS1569I07
HMS1920A08
HMS2091G16
HMS502F15
HSDB 3044
IDI1_000753
KBio1_000753
KBio2_001322
KBio2_003890
 
KBio2_006458
KBio3_001303
KBioGR_000856
KBioSS_001322
Kolkicin
LOC
LS-279
Lopac0_000310
MEGxp0_001879
MLS001055448
MLS001055448-02
MLS001304089
MLS002153786
MPC-004
MolPort-001-742-594
N-((7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)- acetamide
N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)acetamide
N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[.alpha.]heptalen-7-yl)-acetamide
N-Acetyl trimethylcolchicinic acid methylether
N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide
NCGC00025125-01
NCGC00025125-02
NCGC00025125-03
NCGC00025125-04
NCGC00025125-05
NCGC00025125-06
NCGC00025125-07
NCGC00025125-11
NCGC00169157-01
NCGC00169157-02
NCGC00169157-03
NCI60_041659
NChemBio.2007.10-comp20
NINDS_000753
NSC 757
NSC757
Prestwick0_000363
Prestwick1_000363
Prestwick2_000363
Prestwick3_000363
Prestwick_695
S2284_Selleck
SDCCGMLS-0066633.P001
SMR000058323
SPBio_000289
SPBio_002406
SPECTRUM1500205
Spectrum2_000075
Spectrum3_000362
Spectrum4_000298
Spectrum5_000787
Spectrum_000842
Tocris-1364
UNII-SML2Y3J35T
UPCMLD-DP065
UPCMLD-DP065:001
WLN: L B677 MV&T&J CO1 DO1 EO1 JMV1 NO1
ZINC00621853
binds to tubulin
colchicine
inhibits microtubular assembly
nchembio853-comp2
spindle poison
2
Prednisoneapproved, vet_approvedPhase 4139853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
3Calcium, DietaryPhase 4, Early Phase 15713
4Antirheumatic AgentsPhase 4, Early Phase 110956
5Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 413168
6PovidonePhase 4169
7HormonesPhase 414415
8Hormone AntagonistsPhase 413180
9Anti-Inflammatory AgentsPhase 410729
10Antineoplastic Agents, HormonalPhase 45592
11Antimitotic AgentsPhase 45657
12glucocorticoidsPhase 45103
13
ProbenecidapprovedEarly Phase 12957-66-94911
Synonyms:
4-((Dipropylamino)sulfonyl)benzoic acid
4-(Di-N-propylsulfamoyl)benzoesaeure
4-(Di-n-propylsulfamoyl)benzoesaeure
4-(Dipropylsulfamoyl)benzoic acid
4-(N,N-Dipropylsulfamoyl)benzoesaeure
4-[(dipropylamino)sulfonyl]benzoic acid
57-66-9
AB00052080
AC-2023
AC1L1J86
AC1Q2XQM
AC1Q2XQN
AI3-50078
AKOS000165123
Apurina
BIDD:GT0626
BIDD:PXR0092
BPBio1_000643
BRD-K95237249-001-05-9
BRN 2815775
BSPBio_000583
BSPBio_002227
Bencid
Benecid
Benemid
Benemid (TN)
Benemide
Benuryl
Biokanol Brand of Probenecid
C07372
C13H19NO4S
CAS-57-66-9
CCRIS 3643
CHEBI:177474
CHEMBL897
CID4911
CPD000058280
Col-BENEMID
Col-Probenecid
ColBenemid (co mponent of)
ColBenemid (component of)
Colbenemid
D00475
D011339
DB01032
DivK1c_000056
EINECS 200-344-3
HMS1569N05
HMS1920J22
HMS2092C03
HMS500C18
HSDB 3387
I01-1905
ICN Brand of Probenecid
IDI1_000056
IDIS Brand of Probenecid
KBio1_000056
KBio2_001314
KBio2_003882
KBio2_006450
KBio3_001727
KBioGR_000971
KBioSS_001314
LS-33
MLS000028496
MLS001076472
Major Brand of Probenecid
Martec Brand of Probenecid
Merck Brand of Probenecid
MolPort-000-145-935
NCGC00016251-01
NCGC00016251-02
NCGC00023829-03
 
NCGC00023829-04
NCGC00023829-05
NCGC00023829-06
NCI-C56097
NINDS_000056
NSC 18786
NSC18786
Ophthalmic Brand of Probenecid
Oprea1_416955
P-(Dipropylsulfamoyl)benzoic acid
P8761_SIGMA
Panuric
Parabenem
Parmed Brand of Probenecid
Polycillin-BRB
Polycillin-PRB
Polycillin-PRB (component of)
Prestwick0_000542
Prestwick1_000542
Prestwick2_000542
Prestwick3_000542
Prestwick_809
Pro-Cid
Probalan
Probampacin
Probecid
Proben
Proben-C
Probenecid (JP15/USP/INN)
Probenecid Acid
Probenecid Major Brand
Probenecid Martec Brand
Probenecid Parmed Brand
Probenecid Weimer
Probenecid Zenith Brand
Probenecid [INN:BAN:JAN]
Probenecid acid
Probenecida
Probenecida [INN-Spanish]
Probenecide
Probenecide [INN-French]
Probenecidum
Probenecidum [INN-Latin]
Probenemid
Probenicid
Probenid
Probexin
Prolongine
Robenecid
SAM002554923
SBB028597
SMR000058280
SPBio_001327
SPBio_002504
SPECTRUM1500502
Spectrum2_001294
Spectrum3_000554
Spectrum4_000486
Spectrum5_001419
Spectrum_000834
Sulprin
Synergid R
Tubophan
UNII-PO572Z7917
Uricosid
Urocid
Valdecasas Brand of Probenecid
WLN: QVR DSWN3&3
Zenith Brand of Probenecid
p-(Dipropylsulfamoyl)benzoic acid
p-(Dipropylsulfamyl)benzoic acid
p-[Dipropylsulfamoyl]benzoic acid
probenecid
probenicid
14Bone Density Conservation Agents3376
15Renal AgentsEarly Phase 1754

Interventional clinical trials:

idNameStatusNCT IDPhase
1Postmarketing Study to Determine Performance of the SIGMA HP® PARTIAL KNEE SYSTEMCompletedNCT01529099Phase 4
2Trial of Colchicine Versus Prednisone for the Treatment of Acute CPPD ArthritisNot yet recruitingNCT03128905Phase 4
3Diagnostic Rentability of Screening for Associated Conditions in Calcium Pyrophosphate Deposition Disease PatientsCompletedNCT00453128
4Ultrasound and X-ray in Detecting Articular Cartilage CalcificationCompletedNCT00797537
5A Study to Evaluate BioMarkers in Blood Samples in Subjects With Rheumatoid ArthritisCompletedNCT01209585
6Effect of Probenecid on Synovial Fluid ATP Levels in CPPDRecruitingNCT02243631Early Phase 1
7Role of ASICs in Human Inflammatory PainRecruitingNCT01867840
8Regulatory B Cells in Inflammatory Rheumatisms and Biomarkers of Response to Biologic TreatmentsRecruitingNCT01642706

Search NIH Clinical Center for Chondrocalcinosis


Cochrane evidence based reviews: chondrocalcinosis

Genetic Tests for Chondrocalcinosis

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Anatomical Context for Chondrocalcinosis

About this section

MalaCards organs/tissues related to Chondrocalcinosis:

36
Bone, Testes, Lung

FMA organs/tissues related to Chondrocalcinosis:

17
Joint

Publications for Chondrocalcinosis

About this section

Articles related to Chondrocalcinosis:

(show top 50)    (show all 77)
idTitleAuthorsYear
1
Evaluation of Chondrocalcinosis and Associated Knee Joint Degeneration Using MR Imaging: Data from the Osteoarthritis Initiative. (27704199)
2016
2
Prevalence of asymptomatic chondrocalcinosis in the pelvis. (27037810)
2016
3
Ultrasonography: A Useful Tool for the Diagnosis of Chondrocalcinosis of the Sternoclavicular Joint. (27252495)
2016
4
The prevalence of chondrocalcinosis of the symphysis pubis on CT scan and correlation with calcium pyrophosphate dihydrate crystal deposition disease. (26861035)
2016
5
Case Report: Cervical chondrocalcinosis as a complication of Gitelman syndrome. (27303630)
2016
6
Rapid Growth of Lung Nodules due to Combined Pulmonary Vasculitis, Silicoanthracosis, and Chondrocalcinosis. (27478398)
2016
7
Chondrocalcinosis and Gitelman syndrome. (27026693)
2016
8
Comparison of outcomes after UKA in patients with and without chondrocalcinosis: a matched cohort study. (25786825)
2015
9
Chondrocalcinosis related to familial hypomagnesemia with hypercalciuria and nephrocalcinosis. (25720051)
2015
10
A gain of function mutation in TNFRSF11B encoding osteoprotegerin causes osteoarthritis with chondrocalcinosis. (24743232)
2015
11
Rates of meniscal tearing in patients with chondrocalcinosis. (25431326)
2015
12
Osteoarthritis and scapholunate instability in chondrocalcinosis. (25577977)
2015
13
Does chondrocalcinosis associate with a distinct radiographic phenotype of osteoarthritis in knees and hips? - a case-control study. (26223458)
2015
14
Association between low cortical bone mineral density, soft-tissue calcification, vascular calcification and chondrocalcinosis: a case-control study. (23912799)
2014
15
Does chondrocalcinosis affect Knee Society scores and range of motion after TKA? (24385044)
2014
16
The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case-control study. (24467728)
2014
17
Effectiveness and safety of infliximab in two cases of severe chondrocalcinosis: nine years of follow-up. (25436167)
2014
18
Reply to the comment by Verhoeven et al. about the article "Efficacy of anakinra in articular chondrocalcinosis--report of three cases" Joint Bone Spine 2012;79:330-1. (23165180)
2013
19
Comparison of three imaging techniques in diagnosis of chondrocalcinosis of the knees in calcium pyrophosphate deposition disease. (23382359)
2013
20
Evidence of a systemic predisposition to chondrocalcinosis and association between chondrocalcinosis and osteoarthritis at distant joints: a cross-sectional study. (23335553)
2013
21
The prevalence of chondrocalcinosis (CC) of the acromioclavicular (AC) joint on chest radiographs and correlation with calcium pyrophosphate dihydrate (CPPD) crystal deposition disease. (23609408)
2013
22
Gitelman's syndrome associated with chondrocalcinosis: a case report. (24021031)
2013
23
Chondrocalcinosis of femoro-tibial and proximal tibio-fibular joints in cadaveric specimens: a high-resolution CT imaging study of the calcification distribution. (23372802)
2013
24
Efficacy of anakinra in articular chondrocalcinosis: report of three cases. (22341584)
2012
25
Investigating ANKH and ENPP1 in Slovakian families with chondrocalcinosis. (21811784)
2012
26
Chondrocalcinosis is common in the absence of knee involvement. (23036436)
2012
27
Interspinous bursitis and chondrocalcinosis. (22840475)
2012
28
Some historical remarks on microcrystalline arthritis (gout and chondrocalcinosis). (22303526)
2011
29
Epidemiology of gout and chondrocalcinosis. (22303527)
2011
30
Spondyloarthritis, diffuse idiopathic skeletal hyperostosis (DISH) and chondrocalcinosis. (19731619)
2009
31
Familial hypocalciuric hypercalcemia revealed by chondrocalcinosis. (19467900)
2009
32
Craniometaphyseal dysplasia and chondrocalcinosis cosegregating in a family with an ANKH mutation. (19449425)
2009
33
The H63D variant in the HFE gene predisposes to arthralgia, chondrocalcinosis and osteoarthritis. (17284543)
2007
34
Investigation of the role of ENPP1 and TNAP genes in chondrocalcinosis. (17043047)
2007
35
Lumbar radiculopathy due to chondrocalcinosis. (16717221)
2006
36
Ectopic calcification among families in the Azores: clinical and radiologic manifestations in families with diffuse idiopathic skeletal hyperostosis and chondrocalcinosis. (16575860)
2006
37
Genetics of chondrocalcinosis. (15951203)
2005
38
Association of sporadic chondrocalcinosis with a -4-basepair G-to-A transition in the 5'-untranslated region of ANKH that promotes enhanced expression of ANKH protein and excess generation of extracellular inorganic pyrophosphate. (15818664)
2005
39
Hypomagnesemia and chondrocalcinosis in short bowel syndrome. (16331778)
2005
40
Chondrocalcinosis secondary to hypomagnesemia in Gitelman's syndrome. (16142886)
2005
41
Autosomal dominant early childhood seizures associated with chondrocalcinosis and a mutation in the ANKH Gene. (15461680)
2004
42
Chondrocalcinosis and hypomagnesaemia in a patient with a new mutation in the gene of the thiazide-sensitive Na-Cl cotransporter]. (15002785)
2003
43
Mutations in ANKH cause chondrocalcinosis. (12297987)
2002
44
Genetic testing for haemochromatosis in patients with chondrocalcinosis. (12117686)
2002
45
Physical map and characterization of transcripts in the candidate interval for familial chondrocalcinosis at chromosome 5p15.1. (10610710)
1999
46
Hypomagnesemia and chondrocalcinosis in Gitelman syndrome. (10492336)
1999
47
Gitelman syndrome and chondrocalcinosis. (10069232)
1999
48
Association of Paget's disease of bone with articular chondrocalcinosis and pseudogout. (9712120)
1998
49
Osteopoikilosis and chondrocalcinosis. (19078135)
1997
50
Linkage of early-onset osteoarthritis and chondrocalcinosis to human chromosome 8q. (7887424)
1995

Variations for Chondrocalcinosis

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Expression for genes affiliated with Chondrocalcinosis

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Search GEO for disease gene expression data for Chondrocalcinosis.

Pathways for genes affiliated with Chondrocalcinosis

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GO Terms for genes affiliated with Chondrocalcinosis

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Cellular components related to Chondrocalcinosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056159.3ALPL, ENPP1, HFE, REN, TNFRSF11B
2integral component of plasma membraneGO:00058878.8ANKH, CASR, ENPP1, HFE, SLC12A3, TNFRSF11B
3plasma membraneGO:00058866.0ALPL, ANKH, CASR, ENPP1, GNA11, HFE

Biological processes related to Chondrocalcinosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1inorganic diphosphate transportGO:003050510.5ANKH, ENPP1
2regulation of bone mineralizationGO:003050010.5ANKH, ENPP1
3biomineral tissue developmentGO:003121410.4ALPL, ENPP1
4response to lipopolysaccharideGO:00324969.7ALPL, REN, TNFRSF11B
5skeletal system developmentGO:00015018.9ALPL, ANKH, GNA11, TNFRSF11B

Sources for Chondrocalcinosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet