MCID: CHN010
MIFTS: 39

Chondroma malady

Rare diseases, Cancer diseases categories

Aliases & Classifications for Chondroma

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Aliases & Descriptions for Chondroma:

Name: Chondroma 10 45 47 12 65 36
Central Chondroma 10
 
Chondroma Nos 10
Enchondroma 65


Classifications:



External Ids:

Disease Ontology10 DOID:2602
NCIt42 C53459
MeSH36 D002812

Summaries for Chondroma

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Wikipedia:68 A chondroma is a benign cartilaginous tumor, which is encapsulated with a lobular growing pattern. more...

MalaCards based summary: Chondroma, also known as central chondroma, is related to paragangliomas 1, with or without deafness and paraganglioma and gastric stromal sarcoma. An important gene associated with Chondroma is SDHD (Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein), and among its related pathways are Citrate cycle (TCA cycle) and Pyruvate metabolism and Citric Acid (TCA) cycle. Affiliated tissues include tongue, bone and lung, and related mouse phenotypes are limbs/digits/tail and growth/size/body.

Disease Ontology:10 A cell type benign neoplasm that is a cartilaginous tumor encapsulated with a lobular growing pattern.

Related Diseases for Chondroma

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Diseases related to Chondroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 109)
idRelated DiseaseScoreTop Affiliating Genes
1paragangliomas 1, with or without deafness29.8SDHB, SDHC, SDHD
2paraganglioma and gastric stromal sarcoma29.8SDHB, SDHC, SDHD
3gastrointestinal stromal tumor29.5ACTC1, SDHB, SDHC, SDHD
4periostitis10.9
5extraskeletal chondroma10.7
6juxtacortical chondroma10.6
7laryngitis10.6
8chondrosarcoma10.5
9paraganglioma10.5
10cervicitis10.5
11leiomyosarcoma10.4
12central nervous system chondroma10.3
13meningitis10.3
14carney triad10.3
15osteochondroma10.3
16asthma10.2
17chondroblastoma10.2
18phalanx chondroma10.2
19gastric leiomyosarcoma10.2
20enchondroma10.2
21choristoma10.2
22psoriasis10.2ACTC1, CTNNB1
23paranoid schizophrenia10.2CTNNB1, GLI1
24polymyositis10.2ACTC1, CTNNB1
25fibromatosis multiple non ossifying10.1ACTC1, CTNNB1
26anterior compartment syndrome10.1CTNNB1, PTH1R
27in situ pulmonary adenocarcinoma10.1ACTC1, CTNNB1
28inherited blood coagulation disease10.1CTNNB1, GLI1
29chordoma10.1
30radiculopathy10.1
31cerebritis10.1
32epithelioid leiomyosarcoma10.1
33hyperostosis10.1
34neuropathy10.1
35sarcoma10.1
36carpotarsal osteochondromatosis10.1
37cataract hutterite type10.1SDHB, SDHD
38rothmund-thomson syndrome type 210.1SDHB, SDHD
39anus leiomyoma10.1SDHB, SDHD
40autosomal recessive cerebellar ataxia-epilepsy-intellectual disability syndrome due to tud deficiency10.1ACTC1, PTH1R
41autosomal dominant charcot-marie-tooth disease type 2a210.0ACTC1, HMGA2
42localized pulmonary fibrosis10.0ACTC1, HMGA2
43glossitis10.0ACTC1, SDHB, SDHD
44gastrointestinal system cancer10.0CTNNB1, HMGA2
45steroid lipomatosis10.0HMGA2, SDHB
46choroid plexus papilloma10.0
47lipoma10.0
48tendinitis10.0
49sinusitis10.0
50choroiditis10.0

Graphical network of the top 20 diseases related to Chondroma:



Diseases related to chondroma

Symptoms for Chondroma

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Drugs & Therapeutics for Chondroma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Chondroma


Cochrane evidence based reviews: Chondroma

Genetic Tests for Chondroma

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Anatomical Context for Chondroma

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MalaCards organs/tissues related to Chondroma:

33
Tongue, Bone, Lung, Trachea, Liver, Cortex, Spinal cord

Animal Models for Chondroma or affiliated genes

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MGI Mouse Phenotypes related to Chondroma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.1CTNNB1, GLI1, HMGA2, PTH1R
2MP:00053787.2ACTC1, CTNNB1, GLI1, HMGA2, PTH1R, SDHD

Publications for Chondroma

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Articles related to Chondroma:

(show top 50)    (show all 531)
idTitleAuthorsYear
1
True cutaneous chondroma: a case report. (25998426)
2015
2
A rare case of bladder chondroma. (25844100)
2015
3
True chondroma of the mandibular condyle: A rare case. (25593880)
2014
4
Intracranial extra-axial chondroma: a case report. (24614393)
2014
5
Chondroma located in cerebral parenchyma without meningeal attachment. (23172440)
2012
6
Extraskeletal chondroma in the auricle. (21119479)
2010
7
Periosteal chondroma of the pediatric cervical spine. (19278317)
2009
8
Massive chondroma of pelvis - case report. (19828919)
2009
9
Atypical location of a solitary intracranial chondroma without meningeal attachment. (17614089)
2007
10
Cutaneous chondroma with overlying pigmentation clinically mimicking dermatofibroma. (16403116)
2006
11
Intracortical chondroma: a report of two cases. (16284766)
2006
12
Nasal septum chondroma: a case report. (15875440)
2005
13
Laparoscopic presentation of a rib chondroma. (14676003)
2004
14
Soft-tissue chondroma in a finger: a case report. (12152379)
2002
15
Soft-tissue chondroma in the thumb. (12409791)
2002
16
Periosteal chondroma presenting as a subcutaneous mass in the thumb. (11733159)
2001
17
DNA flow cytometric analysis of chest-wall chondroma and chondrosarcoma. (8976036)
1996
18
Extraskeletal chondroma of the foot. (8867554)
1996
19
Musculoskeletal case of the day. Periosteal (juxtacortical) chondroma. (7785598)
1995
20
Soft tissue chondroma of the fallopian tube. Differential diagnosis and histogenetic considerations. (7567687)
1995
21
Cardiac valvular chondroma. (7979695)
1994
22
Skull base chondroma of extracranial origin. (7822182)
1994
23
Soft-tissue chondroma as a cause of calcinosis in a patient with CREST syndrome. (8457459)
1993
24
Chondroma of the cervical spinal canal. Case report. (1306207)
1992
25
Benign cartilaginous tumor (chondroma) of the liver. (1634084)
1992
26
Intra-tendinous chondroma of a flexor tendon. (1779169)
1991
27
Chondroma of the lumbar spine, a rare cause of sciatica: case report. (2330093)
1990
28
Ossifying parasellar chondroma. Case report. (3117983)
1987
29
Chondroma of the nasal cavity and nasopharynx--a case of chondroma arising from the nasal septum. (3449038)
1987
30
Chondroma of falx: CT findings. (3782554)
1986
31
Case report 354: Chondroma of soft tissues with dystrophic calcification. (3961527)
1986
32
Extraskeletal ossifying chondroma in the knee. A case report. (3984711)
1985
33
Periosteal chondroma: another cause of carpal tunnel syndrome. (6721390)
1984
34
Malignant chondroma. (6582165)
1983
35
Orbital chondroma rodens in a dog. (500440)
1979
36
Intracerebral chondroma. (483149)
1979
37
The nasal chondroma. 2 case reports and a survey of the literature. (864317)
1977
38
Non-epithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx: a clinicopathologic study. 3. Cartilaginous tumors (chondroma, chondrosarcoma). (4853358)
1974
39
Periosteal chondroma. (4506239)
1972
40
Intracranial solitary chondroma of dural origin. (5459528)
1970
41
Case reports and technical notes. Chondroma of the cervical spine. Case report. (5684408)
1968
42
Chondroma of the larynx; report of a case with recurrence after twenty-eight years. (13636589)
1959
43
An endobronchial chondroma in a cachectic psychotic with hypopituitarism. (13253916)
1955
44
Chondroma of the vocal cord. (15412306)
1950
45
Chondroma of the larynx; report of a case. (15393512)
1949
46
Laryngeal chondroma. (18892972)
1948
47
Chondroma of the larynx; report of a case. (18921039)
1948
48
Chondroma of right knee]. (20280022)
1947
49
Chondroma of eighth costal cartilage]. (21001781)
1946
50
Osteofibro-chondroma of the scapula in a new born infant. (20275903)
1946

Variations for Chondroma

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Expression for genes affiliated with Chondroma

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Search GEO for disease gene expression data for Chondroma.

Pathways for genes affiliated with Chondroma

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GO Terms for genes affiliated with Chondroma

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Cellular components related to Chondroma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein-DNA complexGO:00329939.4CTNNB1, HMGA2
2respiratory chain complex IIGO:00452739.4SDHB, SDHC
3mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)GO:00057499.2SDHB, SDHC, SDHD

Biological processes related to Chondroma according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1aerobic respirationGO:000906010.1SDHB, SDHC
2tricarboxylic acid cycleGO:00060999.9SDHB, SDHC, SDHD
3epithelial to mesenchymal transitionGO:00018379.9CTNNB1, HMGA2
4cell maturationGO:00484699.8CTNNB1, PTH1R
5bone resorptionGO:00454539.7CTNNB1, PTH1R
6pituitary gland developmentGO:00219839.7GLI1, HMGA2
7regulation of osteoblast differentiationGO:00456679.6CTNNB1, GLI1
8dorsal/ventral pattern formationGO:00099539.6CTNNB1, GLI1
9respiratory electron transport chainGO:00229049.5SDHB, SDHC, SDHD
10cellular metabolic processGO:00442379.5SDHB, SDHC, SDHD
11chondrocyte differentiationGO:00020629.5HMGA2, PTH1R
12proximal/distal pattern formationGO:00099549.2CTNNB1, GLI1
13positive regulation of gene expressionGO:00106288.6ACTC1, CTNNB1, HMGA2
14positive regulation of cell proliferationGO:00082848.0CTNNB1, GLI1, HMGA2, PTH1R

Molecular functions related to Chondroma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ubiquinone bindingGO:004803910.1SDHB, SDHD
2succinate dehydrogenase activityGO:000010410.1SDHC, SDHD
3succinate dehydrogenase (ubiquinone) activityGO:000817710.0SDHB, SDHC
4electron carrier activityGO:00090559.3SDHB, SDHC, SDHD
5SMAD bindingGO:00463329.1CTNNB1, HMGA2

Sources for Chondroma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet