MCID: CHN010
MIFTS: 39

Chondroma malady

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Chondroma

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Aliases & Descriptions for Chondroma:

Name: Chondroma 11 46 13 48 37 66
Central Chondroma 11
 
Chondroma Nos 11
Enchondroma 66

Classifications:



External Ids:

Disease Ontology11 DOID:2602
MeSH37 D002812
NCIt43 C53459

Summaries for Chondroma

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Wikipedia:69 A chondroma is a benign cartilaginous tumor, which is encapsulated with a lobular growing pattern. more...

MalaCards based summary: Chondroma, also known as central chondroma, is related to gastrointestinal stromal tumor and extraskeletal chondroma, and has symptoms including pain An important gene associated with Chondroma is CTNNB1 (Catenin Beta 1), and among its related pathways are Cell adhesion_Cadherin-mediated cell adhesion and Development_Hedgehog and PTH signaling pathways in bone and cartilage development. Affiliated tissues include tongue, bone and spinal cord, and related mouse phenotypes are limbs/digits/tail and craniofacial.

Disease Ontology:11 A cell type benign neoplasm that is a cartilaginous tumor encapsulated with a lobular growing pattern.

Related Diseases for Chondroma

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Diseases related to Chondroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 84)
idRelated DiseaseScoreTop Affiliating Genes
1gastrointestinal stromal tumor28.7ACTC1, PDGFRA, SDHB
2extraskeletal chondroma12.2
3juxtacortical chondroma12.1
4central nervous system chondroma11.9
5dysplasia epiphysealis hemimelica with chondromas and osteochondromas11.9
6phalanx chondroma11.9
7carney triad11.2
8carpotarsal osteochondromatosis11.0
9periostitis10.6
10colonic pseudo-obstruction10.5CTNNB1, GLI1
11adenomyoma10.4CTNNB1, PTH1R
12central nervous system sarcoma10.4ACTC1, CTNNB1
13melanotic medulloblastoma10.3CTNNB1, GLI1
14polyomavirus allograft nephropathy10.3ACTC1, CTNNB1
15foramen magnum meningioma10.3CTNNB1, GLI1
16laryngitis10.3
17lateral medullary syndrome10.3CTNNB1, PDGFRA
18chondrosarcoma10.3
19paraganglioma10.2
20pura syndrome10.2ACTC1, PDGFRA
21mild phosphoribosylpyrophosphate synthetase superactivity10.2ACTC1, PTH1R
22cervicitis10.2
23leiomyosarcoma10.1
24pancreatic somatostatinoma10.1CTNNB1, GLI1
25small cell neuroendocrine carcinoma10.1CTNNB1, PTH1R
26desmoplastic infantile astrocytoma10.1CTNNB1, PDGFRA
27fryns macrocephaly10.1GALNT3, PTH1R
28anus leiomyosarcoma10.1ACTC1, PDGFRA
29meningitis10.0
30osteochondroma10.0
31gallbladder papillomatosis10.0CTNNB1, PDGFRA
32paragangliomas 1, with or without deafness9.9
33chondroid chordoma9.9
34skin glomangioma9.9ACTC1, SDHB
35asthma9.9
36chondroblastoma9.9
37gastric leiomyosarcoma9.9
38enchondroma9.9
39dysgammaglobulinemia9.9PTH1R, SDHB
40medulloblastoma9.9CTNNB1, GLI1, PDGFRA
41chordoma9.8
42sarcoma9.8
43hyperostosis9.8
44cerebritis9.8
45radiculopathy9.8
46epithelioid leiomyosarcoma9.8
47neuropathy9.8
48neutrophil immunodeficiency syndrome9.8ACTC1, PDGFRA
49mercaptolactate-cysteine disulfiduria9.8PDGFRA, SDHB
50paraganglioma and gastric stromal sarcoma9.7

Graphical network of the top 20 diseases related to Chondroma:



Diseases related to chondroma

Symptoms for Chondroma

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UMLS symptoms related to Chondroma:


pain

Drugs & Therapeutics for Chondroma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone SarcomasRecruitingNCT02389244Phase 2

Search NIH Clinical Center for Chondroma


Cochrane evidence based reviews: chondroma

Genetic Tests for Chondroma

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Anatomical Context for Chondroma

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MalaCards organs/tissues related to Chondroma:

34
Tongue, Bone, Spinal cord, Lung, Trachea, Liver, Cortex

Animal Models for Chondroma or affiliated genes

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MGI Mouse Phenotypes related to Chondroma:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.3CTNNB1, GALNT3, GLI1, PDGFRA, PTH1R
2MP:00053828.2CTNNB1, GALNT3, GLI1, PDGFRA, PTH1R
3MP:00053818.0CTNNB1, GALNT3, GLI1, PDGFRA, PTH1R

Publications for Chondroma

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Articles related to Chondroma:

(show top 50)    (show all 547)
idTitleAuthorsYear
1
Malignant transformation of a tracheal chondroma: The second reported case and review of the literature. (27185409)
2016
2
Pulmonary chondroma: A clinicopathological study of 29 cases and a review of the literature. (27602219)
2016
3
Arytenoid cartilage chondroma. (25960446)
2015
4
A rare case of giant soft tissue chondroma of the wrist: A cytopathological study with review of the literature. (25190983)
2014
5
Imaging features of juxtacortical chondroma in children. (23955368)
2014
6
Sellar collision tumor involving pituitary gonadotroph adenoma and chondroma: a potential clinical diagnosis. (19760170)
2011
7
Solitary intracerebral chondroma without meningeal attachment: a case report with review of the literature. (21672374)
2011
8
Periosteal chondroma of the pediatric cervical spine. (19278317)
2009
9
Massive chondroma of pelvis - case report. (19828919)
2009
10
A true chondroma cutis. (19415816)
2009
11
Five cases of chondroma involving the external auditory canal. (18242908)
2008
12
Cutaneous chondroma with overlying pigmentation clinically mimicking dermatofibroma. (16403116)
2006
13
Intracortical chondroma: a report of two cases. (16284766)
2006
14
Nasal septum chondroma: a case report. (15875440)
2005
15
Chondroma of the subcutaneous bursa of the Achilles tendon. (16536214)
2005
16
Soft-tissue chondroma in the thumb. (12409791)
2002
17
Laryngeal chondroma. (12008653)
2002
18
Chondroma of the bony external auditory canal. (11593182)
2001
19
Differentiation between chondroma and squamous cell carcinoma: evaluation of subtraction image of MRI. (9819772)
1998
20
Extraskeletal chondroma of the foot. (8867554)
1996
21
Musculoskeletal case of the day. Periosteal (juxtacortical) chondroma. (7785598)
1995
22
Cardiac valvular chondroma. (7979695)
1994
23
Solitary intracranial chondroma of the convexity dura: case report. (8235973)
1993
24
Chondroma of the nasal cavity and nasopharynx--a case of chondroma arising from the nasal septum. (3449038)
1987
25
Chondroma of falx: CT findings. (3782554)
1986
26
Extraskeletal ossifying chondroma in the knee. A case report. (3984711)
1985
27
Intracranial solitary chondroma. Case report. (6737067)
1984
28
Primary chondroma of the lung. (6530256)
1984
29
Chondroma of the skull base. A case report. (6822775)
1983
30
The triad of gastric epithelioid leiomyosarcoma, pulmonary chondroma, and functioning extra-adrenal paraganglioma: a five-year review. (6843355)
1983
31
The nasal chondroma. 2 case reports and a survey of the literature. (864317)
1977
32
Non-epithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx: a clinicopathologic study. 3. Cartilaginous tumors (chondroma, chondrosarcoma). (4853358)
1974
33
Intracranial solitary chondroma of dural origin. (5459528)
1970
34
Chondroma of the tongue. (5267622)
1970
35
Chondroma of the palate. Case report. (5279867)
1970
36
AN EXCEPTIONALLY LARGE CHONDROMA OF THE MAXILLA: CASE REPORT. (14256819)
1965
37
Chondroma of the tongue. (5213226)
1965
38
Intracranial meningeal chondroma. (14490078)
1961
39
A case of pure endobronchial chondroma. (13855684)
1960
40
Solitary chondroma of the right main bronchus. (13724192)
1960
41
The roentgenologic characteristics of chondroma of the larynx. (13595164)
1958
42
Periosteal chondroma; a report of two cases. (13298000)
1956
43
An endobronchial chondroma in a cachectic psychotic with hypopituitarism. (13253916)
1955
44
Primary chondroma of the lung. (14391170)
1955
45
Chondroma of the tongue. (13111777)
1953
46
Chondroma of the vocal cord. (15412306)
1950
47
Chondroma of the larynx; report of a case. (15393512)
1949
48
Chondroma of the larynx; report of a case. (18921039)
1948
49
Chondroma of right knee]. (20280022)
1947
50
Chondroma. (20988923)
1946

Variations for Chondroma

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Expression for genes affiliated with Chondroma

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Search GEO for disease gene expression data for Chondroma.

Pathways for genes affiliated with Chondroma

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GO Terms for genes affiliated with Chondroma

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Biological processes related to Chondroma according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1regulation of osteoblast differentiationGO:004566710.1CTNNB1, GLI1
2cell maturationGO:004846910.0CTNNB1, PTH1R
3bone resorptionGO:004545310.0CTNNB1, PTH1R
4cardiac myofibril assemblyGO:005500310.0ACTC1, PDGFRA
5proximal/distal pattern formationGO:00099549.9CTNNB1, GLI1
6positive regulation of DNA replicationGO:00457409.8GLI1, PDGFRA
7embryonic cranial skeleton morphogenesisGO:00487019.8CTNNB1, PDGFRA
8dorsal/ventral pattern formationGO:00099539.5CTNNB1, GLI1
9positive regulation of cell proliferationGO:00082848.8CTNNB1, GLI1, PDGFRA, PTH1R

Sources for Chondroma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet