MCID: CHR033
MIFTS: 43

Chordoid Glioma malady

Neuronal diseases, Cancer diseases categories

Summaries for Chordoid Glioma

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32MalaCards
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MalaCards: Chordoid Glioma, also known as chordoid glioma of the third ventricle, is related to third ventricle chordoid glioma and choroiditis. An important gene associated with Chordoid Glioma is S100B (S100 calcium binding protein B), and among its related pathways is Spinal Cord Injury. The compounds streptozotocin and orcein have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and hypothalamus, and related mouse phenotypes are normal and vision/eye.

Aliases & Classifications for Chordoid Glioma

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8Disease Ontology, 10DISEASES, 48Orphanet, 60UMLS, 39NCIt, 56SNOMED-CT, 57SNOMED-CT via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases


Aliases & Descriptions:

chordoid glioma 8 10 48
chordoid glioma of the third ventricle 60


External Ids:

Disease Ontology8 DOID:3774
NCIt39 C5592
SNOMED-CT56 128789002
SNOMED-CT via Orphanet57 128789002

Related Diseases for Chordoid Glioma

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Chordoid Glioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 123)
idRelated DiseaseScoreTop Affiliating Genes
1third ventricle chordoid glioma10.9
2choroiditis10.1
3panhypopituitarism10.1
4diabetes insipidus10.1
5brain glioma10.1
6papilloma10.0POU4F2
7melanotic neuroectodermal tumor10.0SYP
8dysembryoplastic neuroepithelial tumor10.0SYP
9synovial sarcoma10.0KRT7
10metanephric adenoma10.0KRT7
11cystadenoma10.0KRT7
12mixed cell type cancer10.0KRT7
13neuroblastoma10.0SYP
14renal oncocytoma10.0KRT7
15medulloepithelioma10.0SYP
16giant cell glioblastoma10.0GFAP
17kidney cancer10.0KRT7
18choroid plexus papilloma10.0GFAP
19cystadenocarcinoma10.0MUC1
20mixed glioma10.0GFAP
21nephrogenic adenoma10.0KRT7
22angiomyolipoma10.0VIM
23ganglioneuroblastoma10.0S100B, SYP
24pseudomyxoma peritonei10.0KRT7
25adenomatoid tumor10.0VIM
26oxyphilic adenoma10.0KRT7
27neurilemmoma10.0GFAP
28subependymal giant cell astrocytoma10.0SYP, S100B
29olfactory neuroblastoma10.0S100B, SYP
30hidradenoma10.0MUC1
31pituitary adenoma10.0CDK4, SYP
32sertoli-leydig cell tumor10.0MUC1, KRT7
33fibrosarcoma10.0VIM
34fibrous meningioma10.0MUC1, S100B
35myxopapillary ependymoma10.0S100B, GFAP
36endometrial carcinoma10.0CDK4, KRT7
37choroid plexus carcinoma10.0GFAP, S100B
38herpes simplex10.0POU4F2
39gliosarcoma10.0GFAP, CDK4
40teratoma10.0KRT7, GFAP
41binswanger's disease10.0GFAP, SYP
42mammary paget's disease10.0KRT7, MUC1
43colorectal cancer10.0MUC1, KRT7
44central neurocytoma10.0GFAP, SYP
45gemistocytic astrocytoma10.0S100B, GFAP
46mucinous cystadenocarcinoma10.0KRT7, MUC1
47cutaneous paget's disease10.0MUC1, KRT7
48leiomyoma10.0VIM, S100B
49glomus tumor10.0SYP, VIM
50gastrointestinal stromal tumor10.0S100B, VIM

Graphical network of the top 20 diseases related to Chordoid Glioma:



Diseases related to chordoid glioma

Clinical Features for Chordoid Glioma

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Drugs & Therapeutics for Chordoid Glioma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Chordoid Glioma

Drug clinical trials:

Search ClinicalTrials for Chordoid Glioma

Search NIH Clinical Center for Chordoid Glioma

Search CenterWatch for Chordoid Glioma

Genetic Tests for Chordoid Glioma

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Anatomical Context for Chordoid Glioma

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32MalaCards
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MalaCards organs/tissues related to Chordoid Glioma:

32
Brain, Testes, Hypothalamus

Animal Models for Chordoid Glioma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Chordoid Glioma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.0S100B, SYP, POU4F2, MUC1, GFAP, RFX3
2MP:00053917.7PTPRS, GFAP, CDK4, MUC1, POU4F2, VIM
3MP:00053847.0POU4F2, CDK4, RGS16, GFAP, KRT7, PTPRS

Publications for Chordoid Glioma

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50PubMed
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Articles related to Chordoid Glioma:

(show all 50)
idTitleAuthorsYear
1
Neuro-Ophthalmologic Features of Chordoid Glioma. (24113763)
2013
2
Therapeutic approach to chordoid glioma of the third ventricle. (23615418)
2013
3
Chordoid glioma of the third ventricle: four cases including one case with papillary features. (22716306)
2013
4
Chordoid glioma: a rare suprasellar mass. (22644806)
2012
5
Chordoid glioma in suprasellar location with extension into the third ventricle: smear preparation morphology of a rare tumor. (22246933)
2012
6
CD99 is expressed in chordoid glioma and suggests ependymal origin. (22102064)
2012
7
Cytology of chordoid glioma of the third ventricle. (22246938)
2012
8
Chordoid glioma of the third ventricle. (22754136)
2012
9
Rarest of the rare: Chordoid glioma infiltrating the optic chiasm. (21697970)
2011
10
Chordoid glioma: a case report and literature review. (21192197)
2011
11
Chordoid glioma of the third ventricle: a case report with review of literature. (21743188)
2011
12
Chordoid glioma: imaging pearls of a unique third ventricular tumor. (21059517)
2010
13
Chordoid glioma : a case report of unusual location and neuroradiological characteristics. (20717514)
2010
14
Chordoid glioma: ten years of a low-grade tumor with high morbidity. (20808539)
2010
15
Diabetes insipidus, panhypopituitarism, and severe mental status deterioration in a patient with chordoid glioma: case report and literature review. (19364693)
2009
16
Chordoid glioma with calcification and neurofilament expression: case report and review of the literature. (18262609)
2009
17
Chordoid glioma with calcification and neurofilament expression: case report and review of the literature (Iwami et al. Surg Neurol 2008;10.1016/j.surneu.2007.07.032). (19329155)
2009
18
Chordoid glioma of the third ventricle: a report of two cases, one with ultrastructural findings. (18498285)
2009
19
Chordoid glioma: a case report and molecular characterization of five cases. (18652591)
2009
20
Chordoid glioma of the third ventricle attached to the optic chiasm. Successful removal through a trans-lamina terminalis approach. (18597929)
2008
21
Chordoid glioma: report of two rare examples with unusual features. (18246456)
2008
22
Chordoid glioma of the third ventricle. (18936876)
2008
23
An incidentally detected third ventricle chordoid glioma. (18040120)
2007
24
Extraventricular unusual glioma in a child with extensive myxoid change resembling chordoid glioma. (17965223)
2007
25
Test and teach. A recurrent third ventricular brain tumour. Diagnosis: Chordoid glioma of the third ventricle. (16753749)
2006
26
Origin of chordoid glioma of the third ventricle. (16594739)
2006
27
Third ventricular chordoid glioma with unusual aggressive behavior. (17185888)
2006
28
The elusive origin of chordoid glioma. (16594734)
2006
29
Chordoid glioma of the third ventricle: Report of a case with cytologic features and utility during intraoperative consultation. (17152286)
2006
30
Chordoid glioma of the third ventricle. (16568345)
2006
31
Third ventricular chordoid glioma: clinicopathological study of two cases with evidence for a poor clinical outcome despite low grade histological features. (16008819)
2005
32
Chordoid glioma: clinicopathologic profile and differential diagnosis of an uncommon tumor. (15504076)
2004
33
Suprasellar chordoid glioma combined with Rathke's cleft cyst. (14629303)
2003
34
Immunohistochemical and ultrastructural study of chordoid glioma of the third ventricle: its tanycytic differentiation. (12748871)
2003
35
Clinicopathological and ultrastructural study in two cases of chordoid glioma. (14604300)
2003
36
Chordoid glioma: report of a case with unusual histologic features, ultrastructural study and review of the literature. (12814253)
2003
37
Third ventricular chordoid glioma: case report and review of the literature. (12765825)
2003
38
Chordoid glioma of the third ventricle: CT and MRI, including perfusion data. (12389135)
2002
39
Chordoid glioma of the third ventricle: a report of two new cases, with further evidence supporting an ependymal differentiation, and review of the literature. (12360048)
2002
40
Chordoid glioma: an uncommon tumour of the third ventricle. (11360380)
2001
41
Chordoid glioma of the third ventricle: an ultrastructural study of three cases with a histogenetic hypothesis. (11224612)
2001
42
Choroid plexus cyst and chordoid glioma. Report of two cases. (16724823)
2001
43
Chordoid glioma: a neoplasm unique to the hypothalamus and anterior third ventricle. (11237967)
2001
44
Pediatric chordoid glioma with chondroid metaplasia. (11826363)
2001
45
Chordoid glioma: a novel tumor of the third ventricle. (11149969)
2000
46
Chordoid glioma of the third ventricle: CT and MR findings. (10752904)
2000
47
Suprasellar chordoid glioma. (10867806)
2000
48
Chordoid glioma of the third ventricle: confirmatory report of a new entity. (10374785)
1999
49
Chordoid glioma of the third ventricle: immunohistochemical and molecular genetic characterization of a novel tumor entity. (10517500)
1999
50
Third ventricular chordoid glioma: a distinct clinicopathologic entity. (9600220)
1998

Genetic Variations for Chordoid Glioma

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Expression for genes affiliated with Chordoid Glioma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Chordoid Glioma

Search GEO for disease gene expression data for Chordoid Glioma.

Pathways for genes affiliated with Chordoid Glioma

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37NCBI BioSystems Database
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Pathways related to Chordoid Glioma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4GFAP, CDK4, VIM

Compounds for genes affiliated with Chordoid Glioma

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Sources:
44Novoseek, 11DrugBank, 24HMDB, 49PharmGKB, 28IUPHAR, 59Tocris Bioscience, 2BitterDB
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Compounds related to Chordoid Glioma according to GeneCards/GeneDecks:

(show top 50)    (show all 64)
idCompoundScoreTop Affiliating Genes
1streptozotocin4410.2SYP, GFAP
2orcein4410.1VIM, S100B
3n-acetylaspartate4410.1SYP, GFAP
42,3-cyclic nucleotide449.9GFAP, S100B
5ganglioside449.7GFAP, SYP, VIM
6alpha-latrotoxin449.7SYP, PTPRS
7catecholamine449.6S100B, VIM, SYP
8progestin449.6CDK4, VIM, MUC1
9acth449.6SYP, S100B, GFAP, MUC1
10dbc-amp449.6SYP, GFAP, S100B, VIM
11eosin449.6VIM, GFAP, MUC1, S100B
12choline44 11 2411.5S100B, VIM, GFAP, SYP
13bromodeoxyuridine449.5CDK4, VIM, GFAP, S100B
14gaba449.5SYP, VIM, S100B, GFAP
15ethanol44 49 11 2412.5GFAP, MUC1, SYP, S100B
16agar449.4VIM, GFAP, CDK4, MUC1
17paclitaxel44 49 1111.4CDK4, VIM, S100B, GFAP
18butyrate449.4GFAP, VIM, CDK4, MUC1
19valine449.4CDK4, POU4F2, S100B, VIM
20cytarabine44 49 1111.4MUC1, GFAP, VIM
21acetylcholine44 49 28 11 2413.4GFAP, VIM, S100B, SYP
225-hydroxytryptamine449.3GFAP, RGS16, SYP, VIM
23s 100449.3GFAP, MUC1, SYP, S100B, VIM
24forskolin44 49 1111.2VIM, S100B, SYP, MUC1, GFAP
25leucine449.2S100B, VIM, SYP, GFAP, CDK4
26estradiol44 11 2411.2MUC1, VIM, SYP, CDK4, GFAP
27creatinine449.2S100B, VIM, GFAP, MUC1, SYP
28matrigel449.1GFAP, KRT7, MUC1, VIM
29genistein44 28 59 2 11 2414.0GFAP, VIM, SYP, CDK4
30mucicarmine449.0KRT7, MUC1, SYP, S100B, VIM
31b 723449.0KRT7, MUC1, VIM, SYP, S100B
32cyclic amp44 2410.0VIM, GFAP, S100B, MUC1, CDK4, SYP
33dexamethasone44 49 28 1111.9SYP, MUC1, CDK4, GFAP, S100B, VIM
34iron44 249.9KRT7, CDK4, VIM, S100B, GFAP
35glutamine448.9SYP, GFAP, S100B, VIM
36alanine448.7S100B, CDK4, RGS16, VIM, GFAP
37arginine448.7CDK4, GFAP, S100B, KRT7, VIM
38reticulin448.7MUC1, KRT7, VIM, S100B, SYP, GFAP
39hematoxylin448.7SYP, GFAP, S100B, MUC1, VIM, KRT7
40formaldehyde44 249.7S100B, SYP, GFAP, VIM, KRT7, MUC1
41lipid448.5SYP, MUC1, VIM, GFAP, S100B, KRT7
42cysteine448.4RGS16, VIM, S100B, SYP, MUC1, CDK4
43glycogen44 249.4S100B, SYP, KRT7, GFAP, MUC1, CDK4
44paraffin448.4KRT7, GFAP, CDK4, VIM, MUC1, SYP
45progesterone44 59 28 11 2412.4CDK4, VIM, KRT7, MUC1, SYP, S100B
46testosterone44 59 11 2411.3MUC1, VIM, GFAP, CDK4, S100B, SYP
47vegf448.3VIM, S100B, SYP, MUC1, CDK4, GFAP
48retinoic acid44 249.3SYP, CDK4, VIM, GFAP, MUC1, KRT7
49estrogen447.9MUC1, KRT7, POU4F2, SYP, CDK4, S100B
50tyrosine447.4PTPRS, GFAP, RGS16, CDK4, S100B, SYP

GO Terms for genes affiliated with Chordoid Glioma

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16Gene Ontology
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Cellular components related to Chordoid Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058829.1KRT7, GFAP, VIM

Biological processes related to Chordoid Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Bergmann glial cell differentiationGO:0600209.8GFAP, VIM
2astrocyte developmentGO:0140029.7GFAP, VIM
3negative regulation of neuron projection developmentGO:0109779.7GFAP, VIM
4intermediate filament organizationGO:0451099.6VIM, GFAP
5long-term synaptic potentiationGO:0602919.6GFAP, S100B

Products for genes affiliated with Chordoid Glioma

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Sources for Chordoid Glioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet