MCID: CHR033
MIFTS: 45

Chordoid Glioma malady

Neuronal diseases, Cancer diseases, Rare diseases categories
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Summaries for Chordoid Glioma

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MalaCards based summary: Chordoid Glioma, also known as chordoid glioma of the third ventricle, is related to third ventricle chordoid glioma and melanotic neuroectodermal tumor. An important gene associated with Chordoid Glioma is S100B (S100 calcium binding protein B), and among its related pathways are Nuclear signaling by ERBB4 and Neuroscience. The compounds n-acetylaspartate and orcein have been mentioned in the context of this disorder. Affiliated tissues include brain, thyroid and testes, and related mouse phenotypes are normal and vision/eye.

Aliases & Classifications for Chordoid Glioma

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Chordoid Glioma, Aliases & Descriptions:

Name: Chordoid Glioma 8 10 48
 
Chordoid Glioma of the Third Ventricle 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

48
chordoid glioma:
Age of onset: Adulthood; Age of death: Adult


External Ids:

Disease Ontology8 DOID:3774
SNOMED-CT57 128789002
NCIt39 C5592

Related Diseases for Chordoid Glioma

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Diseases related to Chordoid Glioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 110)
idRelated DiseaseScoreTop Affiliating Genes
1third ventricle chordoid glioma10.6
2melanotic neuroectodermal tumor10.5SYP
3dysembryoplastic neuroepithelial tumor10.5SYP
4metanephric adenoma10.5KRT7
5choroid plexus papilloma10.5GFAP
6giant cell glioblastoma10.5GFAP
7nephrogenic adenoma10.5KRT7
8mixed glioma10.5GFAP
9pseudomyxoma peritonei10.5KRT7
10neurilemmoma10.5GFAP
11hidradenoma10.4MUC1
12cystadenocarcinoma10.4MUC1
13synovial sarcoma10.4KRT7
14adenomatoid tumor10.4VIM
15olfactory neuroblastoma10.4S100B, SYP
16subependymal giant cell astrocytoma10.4S100B, SYP
17ganglioneuroblastoma10.4S100B, SYP
18myxopapillary ependymoma10.4S100B, GFAP
19choroid plexus carcinoma10.4GFAP, S100B
20binswanger's disease10.3SYP, GFAP
21gemistocytic astrocytoma10.3GFAP, S100B
22central neurocytoma10.3SYP, GFAP
23fibrous meningioma10.3S100B, MUC1
24mammary paget's disease10.3KRT7, MUC1
25amyotrophic lateral sclerosis type 1410.3GFAP, SYP
26mucinous cystadenocarcinoma10.3KRT7, MUC1
27sertoli-leydig cell tumor10.3MUC1, KRT7
28cutaneous paget's disease10.3MUC1, KRT7
29anaplastic oligodendroglioma10.3CDK4, GFAP
30merkel cell carcinoma10.3MUC1, SYP
31brain cancer10.3SYP, GFAP
32gliosarcoma10.3CDK4, GFAP
33papillary ependymoma10.2GFAP, SYP, S100B
34adenosquamous carcinoma10.2KRT7, MUC1
35pineocytoma10.2GFAP, SYP, S100B
36fibrous histiocytoma10.2S100B, VIM
37ganglioglioma10.2SYP, GFAP, S100B
38mucoepidermoid carcinoma10.2KRT7, MUC1
39ganglioneuroma10.2GFAP, S100B, SYP
40rhabdoid meningioma10.2VIM, GFAP
41paraganglioma10.2SYP, S100B, GFAP
42large cell carcinoma10.2KRT7, CDK4, SYP
43astroblastoma10.2VIM, GFAP
44endometrial carcinoma10.2KRT7, MUC1
45smooth muscle tumor10.2VIM, S100B
46panhypopituitarism10.2
47diabetes insipidus10.2
48thyroiditis10.2
49clear cell ependymoma10.2MUC1, VIM
50teratoma10.2KRT7, GFAP

Graphical network of the top 20 diseases related to Chordoid Glioma:



Diseases related to chordoid glioma

Symptoms for Chordoid Glioma

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Drugs & Therapeutics for Chordoid Glioma

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Drug clinical trials:

Search ClinicalTrials for Chordoid Glioma

Search NIH Clinical Center for Chordoid Glioma

Genetic Tests for Chordoid Glioma

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Anatomical Context for Chordoid Glioma

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MalaCards organs/tissues related to Chordoid Glioma:

32
Brain, Thyroid, Testes, Hypothalamus

Animal Models for Chordoid Glioma or affiliated genes

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MGI Mouse Phenotypes related to Chordoid Glioma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.7GFAP, RFX3, MUC1, SYP, S100B
2MP:00053918.5CDK4, MUC1, VIM, PTPRS, GFAP
3MP:00053867.8CDK4, RGS16, S100B, VIM, PTPRS, GFAP
4MP:00053847.1GFAP, CDK4, KRT7, RGS16, VIM, PTPRS

Publications for Chordoid Glioma

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Articles related to Chordoid Glioma:

(show all 50)
idTitleAuthorsYear
1
Expression of thyroid transcription factor 1 in a chordoid glioma. (25248954)
2014
2
Neuro-Ophthalmologic Features of Chordoid Glioma. (24113763)
2013
3
Therapeutic approach to chordoid glioma of the third ventricle. (23615418)
2013
4
Chordoid glioma of the third ventricle: four cases including one case with papillary features. (22716306)
2013
5
Chordoid glioma: a rare suprasellar mass. (22644806)
2012
6
Chordoid glioma in suprasellar location with extension into the third ventricle: smear preparation morphology of a rare tumor. (22246933)
2012
7
CD99 is expressed in chordoid glioma and suggests ependymal origin. (22102064)
2012
8
Cytology of chordoid glioma of the third ventricle. (22246938)
2012
9
Chordoid glioma of the third ventricle. (22754136)
2012
10
Rarest of the rare: Chordoid glioma infiltrating the optic chiasm. (21697970)
2011
11
Chordoid glioma: a case report and literature review. (21192197)
2011
12
Chordoid glioma of the third ventricle: a case report with review of literature. (21743188)
2011
13
Chordoid glioma: imaging pearls of a unique third ventricular tumor. (21059517)
2010
14
Chordoid glioma : a case report of unusual location and neuroradiological characteristics. (20717514)
2010
15
Chordoid glioma: ten years of a low-grade tumor with high morbidity. (20808539)
2010
16
Diabetes insipidus, panhypopituitarism, and severe mental status deterioration in a patient with chordoid glioma: case report and literature review. (19364693)
2009
17
Chordoid glioma with calcification and neurofilament expression: case report and review of the literature. (18262609)
2009
18
Chordoid glioma with calcification and neurofilament expression: case report and review of the literature (Iwami et al. Surg Neurol 2008;10.1016/j.surneu.2007.07.032). (19329155)
2009
19
Chordoid glioma of the third ventricle: a report of two cases, one with ultrastructural findings. (18498285)
2009
20
Chordoid glioma: a case report and molecular characterization of five cases. (18652591)
2009
21
Chordoid glioma of the third ventricle attached to the optic chiasm. Successful removal through a trans-lamina terminalis approach. (18597929)
2008
22
Chordoid glioma: report of two rare examples with unusual features. (18246456)
2008
23
Chordoid glioma of the third ventricle. (18936876)
2008
24
An incidentally detected third ventricle chordoid glioma. (18040120)
2007
25
Extraventricular unusual glioma in a child with extensive myxoid change resembling chordoid glioma. (17965223)
2007
26
Test and teach. A recurrent third ventricular brain tumour. Diagnosis: Chordoid glioma of the third ventricle. (16753749)
2006
27
Origin of chordoid glioma of the third ventricle. (16594739)
2006
28
Third ventricular chordoid glioma with unusual aggressive behavior. (17185888)
2006
29
The elusive origin of chordoid glioma. (16594734)
2006
30
Chordoid glioma of the third ventricle: Report of a case with cytologic features and utility during intraoperative consultation. (17152286)
2006
31
Chordoid glioma of the third ventricle. (16568345)
2006
32
Third ventricular chordoid glioma: clinicopathological study of two cases with evidence for a poor clinical outcome despite low grade histological features. (16008819)
2005
33
Chordoid glioma: clinicopathologic profile and differential diagnosis of an uncommon tumor. (15504076)
2004
34
Suprasellar chordoid glioma combined with Rathke's cleft cyst. (14629303)
2003
35
Immunohistochemical and ultrastructural study of chordoid glioma of the third ventricle: its tanycytic differentiation. (12748871)
2003
36
Clinicopathological and ultrastructural study in two cases of chordoid glioma. (14604300)
2003
37
Chordoid glioma: report of a case with unusual histologic features, ultrastructural study and review of the literature. (12814253)
2003
38
Third ventricular chordoid glioma: case report and review of the literature. (12765825)
2003
39
Chordoid glioma of the third ventricle: CT and MRI, including perfusion data. (12389135)
2002
40
Chordoid glioma of the third ventricle: a report of two new cases, with further evidence supporting an ependymal differentiation, and review of the literature. (12360048)
2002
41
Chordoid glioma: an uncommon tumour of the third ventricle. (11360380)
2001
42
Chordoid glioma of the third ventricle: an ultrastructural study of three cases with a histogenetic hypothesis. (11224612)
2001
43
Chordoid glioma: a neoplasm unique to the hypothalamus and anterior third ventricle. (11237967)
2001
44
Pediatric chordoid glioma with chondroid metaplasia. (11826363)
2001
45
Chordoid glioma: a novel tumor of the third ventricle. (11149969)
2000
46
Chordoid glioma of the third ventricle: CT and MR findings. (10752904)
2000
47
Suprasellar chordoid glioma. (10867806)
2000
48
Chordoid glioma of the third ventricle: confirmatory report of a new entity. (10374785)
1999
49
Chordoid glioma of the third ventricle: immunohistochemical and molecular genetic characterization of a novel tumor entity. (10517500)
1999
50
Third ventricular chordoid glioma: a distinct clinicopathologic entity. (9600220)
1998

Variations for Chordoid Glioma

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Expression for genes affiliated with Chordoid Glioma

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Expression patterns in normal tissues for genes affiliated with Chordoid Glioma

Search GEO for disease gene expression data for Chordoid Glioma.

Pathways for genes affiliated with Chordoid Glioma

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Pathways related to Chordoid Glioma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.8GFAP, S100B
29.5S100B, GFAP, SYP
39.4GFAP, VIM, CDK4
49.2VIM, KRT7

Compounds for genes affiliated with Chordoid Glioma

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Compounds related to Chordoid Glioma according to GeneCards/GeneDecks:

(show top 50)    (show all 82)
idCompoundScoreTop Affiliating Genes
1n-acetylaspartate449.9SYP, GFAP
2orcein449.9VIM, S100B
3alpha-latrotoxin449.8PTPRS, SYP
4streptozotocin449.7SYP, VIM, GFAP
5ganglioside449.6SYP, GFAP, VIM
6acth449.5GFAP, MUC1, SYP, S100B
7dbc-amp449.5SYP, VIM, GFAP, S100B
8ethanol44 50 24 1112.5S100B, GFAP, MUC1, SYP
9progestin449.5MUC1, VIM, CDK4
10choline44 24 1111.5S100B, GFAP, VIM, SYP
11eosin449.5S100B, VIM, GFAP, MUC1
12bromodeoxyuridine449.5S100B, VIM, CDK4, GFAP
13catecholamine449.4VIM, S100B, SYP
14gaba449.4S100B, SYP, VIM, GFAP
15paclitaxel44 50 1111.4GFAP, VIM, CDK4, S100B
16acetylcholine44 50 28 24 1113.4VIM, S100B, GFAP, SYP
17agar449.3MUC1, VIM, GFAP, CDK4
18cytarabine44 50 1111.3MUC1, VIM, GFAP
19butyrate449.3MUC1, CDK4, VIM, GFAP
20s 100449.2SYP, MUC1, VIM, GFAP, S100B
21leucine449.1CDK4, S100B, SYP, GFAP, VIM
225-hydroxytryptamine449.1GFAP, SYP, VIM, RGS16
23genistein44 28 61 2 24 1114.1GFAP, VIM, CDK4, SYP
24forskolin44 50 1111.1SYP, VIM, MUC1, S100B, GFAP
25creatinine449.1SYP, S100B, MUC1, VIM, GFAP
26estradiol44 24 1111.1SYP, GFAP, VIM, MUC1, CDK4
27glutamine449.0SYP, GFAP, S100B, VIM
28matrigel448.8VIM, MUC1, KRT7, GFAP
29cyclic amp44 249.8VIM, CDK4, S100B, SYP, MUC1, GFAP
30dexamethasone44 50 28 1111.8VIM, GFAP, MUC1, S100B, SYP, CDK4
31alanine448.7CDK4, S100B, VIM, GFAP, RGS16
32mucicarmine448.7VIM, MUC1, SYP, S100B, KRT7
33b 723448.7KRT7, VIM, SYP, MUC1, S100B
34iron44 249.6GFAP, VIM, S100B, CDK4, KRT7
35serine448.6S100B, SYP, MUC1, VIM, GFAP, CDK4
36arginine448.5CDK4, KRT7, S100B, VIM, GFAP
37reticulin448.3MUC1, KRT7, S100B, SYP, GFAP, VIM
38hematoxylin448.3SYP, GFAP, VIM, MUC1, S100B, KRT7
39formaldehyde44 249.3SYP, GFAP, S100B, VIM, KRT7, MUC1
40lipid448.2VIM, SYP, S100B, KRT7, MUC1, GFAP
41cysteine448.2CDK4, VIM, MUC1, SYP, GFAP, S100B
42glucose448.0CDK4, GFAP, MUC1, S100B, KRT7
43glycogen44 249.0CDK4, S100B, KRT7, SYP, GFAP, VIM
44paraffin448.0CDK4, S100B, SYP, GFAP, VIM, MUC1
45progesterone44 28 61 24 1112.0CDK4, GFAP, VIM, SYP, MUC1, KRT7
46testosterone44 61 24 1111.0CDK4, MUC1, VIM, S100B, SYP, KRT7
47vegf448.0VIM, GFAP, SYP, MUC1, KRT7, S100B
48estrogen448.0KRT7, S100B, GFAP, VIM, MUC1, CDK4
49retinoic acid44 249.0GFAP, VIM, SYP, S100B, MUC1, KRT7
50tyrosine447.3CDK4, MUC1, KRT7, RGS16, SYP, PTPRS

GO Terms for genes affiliated with Chordoid Glioma

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Cellular components related to Chordoid Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058828.9KRT7, VIM, GFAP

Biological processes related to Chordoid Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of neuronal synaptic plasticityGO:0481689.8S100B, SYP
2Bergmann glial cell differentiationGO:0600209.8GFAP, VIM
3astrocyte developmentGO:0140029.7VIM, GFAP
4intermediate filament organizationGO:0451099.7VIM, GFAP
5negative regulation of neuron projection developmentGO:0109779.7GFAP, VIM
6long-term synaptic potentiationGO:0602919.5S100B, GFAP

Molecular functions related to Chordoid Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055156.6CDK4, KRT7, RGS16, S100B, MUC1, RFX3

Products for genes affiliated with Chordoid Glioma

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Sources for Chordoid Glioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet