MCID: CHR033
MIFTS: 45

Chordoid Glioma malady

Neuronal diseases, Cancer diseases, Rare diseases categories
Download this MalaCard

Summaries for Chordoid Glioma

About this section
Sources:
33MalaCards
See all sources

Fully expand this MalaCard
MalaCards: Chordoid Glioma, also known as chordoid glioma of the third ventricle, is related to third ventricle chordoid glioma and panhypopituitarism. An important gene associated with Chordoid Glioma is S100B (S100 calcium binding protein B), and among its related pathways are Nuclear signaling by ERBB4 and Neuroscience. The compounds n-acetylaspartate and orcein have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and hypothalamus, and related mouse phenotypes are normal and vision/eye.

Aliases & Classifications for Chordoid Glioma

About this section
Sources:
8Disease Ontology, 10DISEASES, 49Orphanet, 62UMLS, 58SNOMED-CT, 40NCIt, 59SNOMED-CT via Orphanet
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

49
chordoid glioma:
Age of onset: Adulthood; Age of death: Adult


Aliases & Descriptions:

chordoid glioma 8 10 49
chordoid glioma of the third ventricle 62


External Ids:

Disease Ontology8 DOID:3774
NCIt40 C5592
SNOMED-CT58 128789002
SNOMED-CT via Orphanet59 128789002

Related Diseases for Chordoid Glioma

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Chordoid Glioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 113)
idRelated DiseaseScoreTop Affiliating Genes
1third ventricle chordoid glioma10.6
2panhypopituitarism10.2
3diabetes insipidus10.2
4choroiditis10.2
5choroid plexus cyst10.2
6melanotic neuroectodermal tumor10.1SYP
7dysembryoplastic neuroepithelial tumor10.1SYP
8metanephric adenoma10.1KRT7
9choroid plexus papilloma10.1GFAP
10giant cell glioblastoma10.1GFAP
11nephrogenic adenoma10.1KRT7
12mixed glioma10.1GFAP
13pseudomyxoma peritonei10.1KRT7
14neurilemmoma10.1GFAP
15hidradenoma10.1MUC1
16cystadenocarcinoma10.1MUC1
17synovial sarcoma10.1KRT7
18adenomatoid tumor10.1VIM
19subependymal giant cell astrocytoma10.1SYP, S100B
20olfactory neuroblastoma10.1SYP, S100B
21ganglioneuroblastoma10.1SYP, S100B
22myxopapillary ependymoma10.1GFAP, S100B
23choroid plexus carcinoma10.1GFAP, S100B
24binswanger's disease10.1GFAP, SYP
25gemistocytic astrocytoma10.1GFAP, S100B
26central neurocytoma10.1GFAP, SYP
27fibrous meningioma10.1MUC1, S100B
28amyotrophic lateral sclerosis10.1SYP, GFAP
29mammary paget's disease10.1MUC1, KRT7
30mucinous cystadenocarcinoma10.1MUC1, KRT7
31sertoli-leydig cell tumor10.1MUC1, KRT7
32cutaneous paget's disease10.1KRT7, MUC1
33anaplastic oligodendroglioma10.1GFAP, CDK4
34glomus tumor10.1VIM, SYP
35merkel cell carcinoma10.1MUC1, SYP
36brain cancer10.1SYP, GFAP
37gliosarcoma10.1GFAP, CDK4
38papillary ependymoma10.1GFAP, SYP, S100B
39adenosquamous carcinoma10.1MUC1, KRT7
40pineocytoma10.1GFAP, SYP, S100B
41fibrous histiocytoma10.1VIM, S100B
42ganglioglioma10.1GFAP, SYP, S100B
43mucoepidermoid carcinoma10.1MUC1, KRT7
44ganglioneuroma10.1S100B, SYP, GFAP
45rhabdoid meningioma10.1GFAP, VIM
46paraganglioma10.1GFAP, SYP, S100B
47large cell carcinoma10.1SYP, KRT7, CDK4
48astroblastoma10.0GFAP, VIM
49endometrial carcinoma10.0KRT7, MUC1
50smooth muscle tumor10.0VIM, S100B

Graphical network of the top 20 diseases related to Chordoid Glioma:



Diseases related to chordoid glioma

Symptoms for Chordoid Glioma

About this section

Drugs & Therapeutics for Chordoid Glioma

About this section
Sources:
42NIH Clinical Center, 6ClinicalTrials
See all sources

Drug clinical trials:

Search ClinicalTrials for Chordoid Glioma

Search NIH Clinical Center for Chordoid Glioma

Genetic Tests for Chordoid Glioma

About this section

Anatomical Context for Chordoid Glioma

About this section
Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Chordoid Glioma:

33
Brain, Testes, Hypothalamus

Animal Models for Chordoid Glioma or affiliated genes

About this section
Sources:
37MGI
See all sources

MGI Mouse Phenotypes related to Chordoid Glioma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.7S100B, SYP, MUC1, RFX3, GFAP
2MP:00053918.5CDK4, MUC1, VIM, PTPRS, GFAP
3MP:00053867.8GFAP, PTPRS, VIM, S100B, RGS16, CDK4
4MP:00053847.1GFAP, PTPRS, VIM, RGS16, KRT7, CDK4

Publications for Chordoid Glioma

About this section
Sources:
52PubMed
See all sources

Articles related to Chordoid Glioma:

(show all 50)
idTitleAuthorsYear
1
Neuro-Ophthalmologic Features of Chordoid Glioma. (24113763)
2013
2
Therapeutic approach to chordoid glioma of the third ventricle. (23615418)
2013
3
Chordoid glioma of the third ventricle: four cases including one case with papillary features. (22716306)
2013
4
Chordoid glioma: a rare suprasellar mass. (22644806)
2012
5
Chordoid glioma in suprasellar location with extension into the third ventricle: smear preparation morphology of a rare tumor. (22246933)
2012
6
CD99 is expressed in chordoid glioma and suggests ependymal origin. (22102064)
2012
7
Cytology of chordoid glioma of the third ventricle. (22246938)
2012
8
Chordoid glioma of the third ventricle. (22754136)
2012
9
Rarest of the rare: Chordoid glioma infiltrating the optic chiasm. (21697970)
2011
10
Chordoid glioma: a case report and literature review. (21192197)
2011
11
Chordoid glioma of the third ventricle: a case report with review of literature. (21743188)
2011
12
Chordoid glioma: imaging pearls of a unique third ventricular tumor. (21059517)
2010
13
Chordoid glioma : a case report of unusual location and neuroradiological characteristics. (20717514)
2010
14
Chordoid glioma: ten years of a low-grade tumor with high morbidity. (20808539)
2010
15
Diabetes insipidus, panhypopituitarism, and severe mental status deterioration in a patient with chordoid glioma: case report and literature review. (19364693)
2009
16
Chordoid glioma with calcification and neurofilament expression: case report and review of the literature. (18262609)
2009
17
Chordoid glioma with calcification and neurofilament expression: case report and review of the literature (Iwami et al. Surg Neurol 2008;10.1016/j.surneu.2007.07.032). (19329155)
2009
18
Chordoid glioma of the third ventricle: a report of two cases, one with ultrastructural findings. (18498285)
2009
19
Chordoid glioma: a case report and molecular characterization of five cases. (18652591)
2009
20
Chordoid glioma of the third ventricle attached to the optic chiasm. Successful removal through a trans-lamina terminalis approach. (18597929)
2008
21
Chordoid glioma: report of two rare examples with unusual features. (18246456)
2008
22
Chordoid glioma of the third ventricle. (18936876)
2008
23
An incidentally detected third ventricle chordoid glioma. (18040120)
2007
24
Extraventricular unusual glioma in a child with extensive myxoid change resembling chordoid glioma. (17965223)
2007
25
Test and teach. A recurrent third ventricular brain tumour. Diagnosis: Chordoid glioma of the third ventricle. (16753749)
2006
26
Origin of chordoid glioma of the third ventricle. (16594739)
2006
27
Third ventricular chordoid glioma with unusual aggressive behavior. (17185888)
2006
28
The elusive origin of chordoid glioma. (16594734)
2006
29
Chordoid glioma of the third ventricle: Report of a case with cytologic features and utility during intraoperative consultation. (17152286)
2006
30
Chordoid glioma of the third ventricle. (16568345)
2006
31
Third ventricular chordoid glioma: clinicopathological study of two cases with evidence for a poor clinical outcome despite low grade histological features. (16008819)
2005
32
Chordoid glioma: clinicopathologic profile and differential diagnosis of an uncommon tumor. (15504076)
2004
33
Suprasellar chordoid glioma combined with Rathke's cleft cyst. (14629303)
2003
34
Immunohistochemical and ultrastructural study of chordoid glioma of the third ventricle: its tanycytic differentiation. (12748871)
2003
35
Clinicopathological and ultrastructural study in two cases of chordoid glioma. (14604300)
2003
36
Chordoid glioma: report of a case with unusual histologic features, ultrastructural study and review of the literature. (12814253)
2003
37
Third ventricular chordoid glioma: case report and review of the literature. (12765825)
2003
38
Chordoid glioma of the third ventricle: CT and MRI, including perfusion data. (12389135)
2002
39
Chordoid glioma of the third ventricle: a report of two new cases, with further evidence supporting an ependymal differentiation, and review of the literature. (12360048)
2002
40
Chordoid glioma: an uncommon tumour of the third ventricle. (11360380)
2001
41
Chordoid glioma of the third ventricle: an ultrastructural study of three cases with a histogenetic hypothesis. (11224612)
2001
42
Choroid plexus cyst and chordoid glioma. Report of two cases. (16724823)
2001
43
Chordoid glioma: a neoplasm unique to the hypothalamus and anterior third ventricle. (11237967)
2001
44
Pediatric chordoid glioma with chondroid metaplasia. (11826363)
2001
45
Chordoid glioma: a novel tumor of the third ventricle. (11149969)
2000
46
Chordoid glioma of the third ventricle: CT and MR findings. (10752904)
2000
47
Suprasellar chordoid glioma. (10867806)
2000
48
Chordoid glioma of the third ventricle: confirmatory report of a new entity. (10374785)
1999
49
Chordoid glioma of the third ventricle: immunohistochemical and molecular genetic characterization of a novel tumor entity. (10517500)
1999
50
Third ventricular chordoid glioma: a distinct clinicopathologic entity. (9600220)
1998

Variations for Chordoid Glioma

About this section

Expression for genes affiliated with Chordoid Glioma

About this section
Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Chordoid Glioma

Search GEO for disease gene expression data for Chordoid Glioma.

Pathways for genes affiliated with Chordoid Glioma

About this section
Sources:
50PathCards, 55Reactome, 5Cell Signaling Technology, 38NCBI BioSystems Database, 60Thomson Reuters
See all sources

Pathways related to Chordoid Glioma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.8GFAP, S100B
29.5S100B, GFAP, SYP
39.4GFAP, VIM, CDK4
49.2VIM, KRT7

Compounds for genes affiliated with Chordoid Glioma

About this section
Sources:
45Novoseek, 51PharmGKB, 24HMDB, 11DrugBank, 29IUPHAR, 61Tocris Bioscience, 3BitterDB
See all sources

Compounds related to Chordoid Glioma according to GeneCards/GeneDecks:

(show top 50)    (show all 82)
idCompoundScoreTop Affiliating Genes
1n-acetylaspartate459.9SYP, GFAP
2orcein459.9VIM, S100B
3alpha-latrotoxin459.8PTPRS, SYP
4streptozotocin459.7SYP, VIM, GFAP
5ganglioside459.6SYP, GFAP, VIM
6acth459.5GFAP, MUC1, SYP, S100B
7dbc-amp459.5SYP, VIM, GFAP, S100B
8ethanol45 51 24 1112.5S100B, GFAP, MUC1, SYP
9progestin459.5MUC1, VIM, CDK4
10choline45 24 1111.5S100B, GFAP, VIM, SYP
11eosin459.5S100B, VIM, GFAP, MUC1
12bromodeoxyuridine459.5S100B, VIM, CDK4, GFAP
13catecholamine459.4VIM, S100B, SYP
14gaba459.4S100B, SYP, VIM, GFAP
15paclitaxel45 51 1111.4GFAP, VIM, CDK4, S100B
16acetylcholine45 51 29 24 1113.4VIM, S100B, GFAP, SYP
17agar459.3MUC1, VIM, GFAP, CDK4
18cytarabine45 51 1111.3MUC1, VIM, GFAP
19butyrate459.3MUC1, CDK4, VIM, GFAP
20s 100459.2SYP, MUC1, VIM, GFAP, S100B
21leucine459.1CDK4, S100B, SYP, GFAP, VIM
225-hydroxytryptamine459.1GFAP, SYP, VIM, RGS16
23genistein45 29 61 3 24 1114.1GFAP, VIM, CDK4, SYP
24forskolin45 51 1111.1SYP, VIM, MUC1, S100B, GFAP
25creatinine459.1SYP, S100B, MUC1, VIM, GFAP
26estradiol45 24 1111.1SYP, GFAP, VIM, MUC1, CDK4
27glutamine459.0SYP, GFAP, S100B, VIM
28matrigel458.8VIM, MUC1, KRT7, GFAP
29cyclic amp45 249.8VIM, CDK4, S100B, SYP, MUC1, GFAP
30dexamethasone45 51 29 1111.8VIM, GFAP, MUC1, S100B, SYP, CDK4
31alanine458.7CDK4, S100B, VIM, GFAP, RGS16
32mucicarmine458.7VIM, MUC1, SYP, S100B, KRT7
33b 723458.7KRT7, VIM, SYP, MUC1, S100B
34iron45 249.6GFAP, VIM, S100B, CDK4, KRT7
35serine458.6S100B, SYP, MUC1, VIM, GFAP, CDK4
36arginine458.5CDK4, KRT7, S100B, VIM, GFAP
37reticulin458.3MUC1, KRT7, S100B, SYP, GFAP, VIM
38hematoxylin458.3SYP, GFAP, VIM, MUC1, S100B, KRT7
39formaldehyde45 249.3SYP, GFAP, S100B, VIM, KRT7, MUC1
40lipid458.2VIM, SYP, S100B, KRT7, MUC1, GFAP
41cysteine458.2CDK4, VIM, MUC1, SYP, GFAP, S100B
42glucose458.0CDK4, GFAP, MUC1, S100B, KRT7
43glycogen45 249.0CDK4, S100B, KRT7, SYP, GFAP, VIM
44paraffin458.0CDK4, S100B, SYP, GFAP, VIM, MUC1
45progesterone45 29 61 24 1112.0CDK4, GFAP, VIM, SYP, MUC1, KRT7
46testosterone45 61 24 1111.0CDK4, MUC1, VIM, S100B, SYP, KRT7
47vegf458.0VIM, GFAP, SYP, MUC1, KRT7, S100B
48estrogen458.0KRT7, S100B, GFAP, VIM, MUC1, CDK4
49retinoic acid45 249.0GFAP, VIM, SYP, S100B, MUC1, KRT7
50tyrosine457.3CDK4, MUC1, KRT7, RGS16, SYP, PTPRS

GO Terms for genes affiliated with Chordoid Glioma

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Chordoid Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058828.9KRT7, VIM, GFAP

Biological processes related to Chordoid Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of neuronal synaptic plasticityGO:0481689.8SYP, S100B
2Bergmann glial cell differentiationGO:0600209.8VIM, GFAP
3astrocyte developmentGO:0140029.7VIM, GFAP
4intermediate filament organizationGO:0451099.7VIM, GFAP
5negative regulation of neuron projection developmentGO:0109779.7VIM, GFAP
6long-term synaptic potentiationGO:0602919.5S100B, GFAP

Molecular functions related to Chordoid Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055156.6CDK4, KRT7, RGS16, S100B, MUC1, RFX3

Products for genes affiliated with Chordoid Glioma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Chordoid Glioma

About this section
4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet