MCID: CHR033
MIFTS: 35

Chordoid Glioma malady

Neuronal, Cancer categories

Summaries for Chordoid Glioma

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33MalaCards
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MalaCards: Chordoid Glioma, also known as chordoid glioma of the third ventricle, is related to third ventricle chordoid glioma and panhypopituitarism. An important gene associated with Chordoid Glioma is S100B (S100 calcium binding protein B), and among its related pathways is Spinal Cord Injury. The compounds streptozotocin and orcein have been mentioned in the context of this disorder. Affiliated tissues include brain and hypothalamus, and related mouse phenotypes are normal and vision/eye.

Aliases & Classifications for Chordoid Glioma

Sources:
8Disease Ontology, 10DISEASES, 49Orphanet, 61UMLS, 40NCIt, 57SNOMED-CT
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer
Anatomical: Neuronal


Aliases & Descriptions:

chordoid glioma 8 10 49
chordoid glioma of the third ventricle 61


External Ids:

Disease Ontology8 DOID:3774
SNOMED-CT57 128789002
NCIt40 C5592

Related Diseases for Chordoid Glioma

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Chordoid Glioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 123)
idRelated DiseaseScoreTop Affiliating Genes
1third ventricle chordoid glioma10.6
2panhypopituitarism10.2
3diabetes insipidus10.2
4brain glioma10.2
5choroid plexus cyst10.2
6papilloma10.0POU4F2
7melanotic neuroectodermal tumor10.0SYP
8dysembryoplastic neuroepithelial tumor10.0SYP
9synovial sarcoma10.0KRT7
10metanephric adenoma10.0KRT7
11cystadenoma10.0KRT7
12mixed cell type cancer10.0KRT7
13neuroblastoma10.0SYP
14renal oncocytoma10.0KRT7
15medulloepithelioma10.0SYP
16giant cell glioblastoma10.0GFAP
17kidney cancer10.0KRT7
18choroid plexus papilloma10.0GFAP
19cystadenocarcinoma10.0MUC1
20mixed glioma10.0GFAP
21nephrogenic adenoma10.0KRT7
22angiomyolipoma10.0VIM
23ganglioneuroblastoma10.0S100B, SYP
24pseudomyxoma peritonei10.0KRT7
25adenomatoid tumor10.0VIM
26oxyphilic adenoma10.0KRT7
27olfactory neuroblastoma10.0S100B, SYP
28neurilemmoma10.0GFAP
29subependymal giant cell astrocytoma10.0S100B, SYP
30hidradenoma10.0MUC1
31pituitary adenoma10.0CDK4, SYP
32sertoli-leydig cell tumor10.0KRT7, MUC1
33fibrosarcoma10.0VIM
34fibrous meningioma10.0MUC1, S100B
35myxopapillary ependymoma10.0S100B, GFAP
36endometrial carcinoma10.0CDK4, KRT7
37herpes simplex10.0POU4F2
38choroid plexus carcinoma10.0S100B, GFAP
39gliosarcoma10.0CDK4, GFAP
40teratoma10.0KRT7, GFAP
41binswanger's disease10.0SYP, GFAP
42mammary paget's disease10.0MUC1, KRT7
43colorectal cancer10.0MUC1, KRT7
44central neurocytoma10.0GFAP, SYP
45gemistocytic astrocytoma10.0S100B, GFAP
46mucinous cystadenocarcinoma10.0MUC1, KRT7
47cutaneous paget's disease10.0MUC1, KRT7
48leiomyoma10.0S100B, VIM
49glomus tumor10.0VIM, SYP
50gastrointestinal stromal tumor10.0S100B, VIM

Graphical network of the top 20 diseases related to Chordoid Glioma:



Diseases related to chordoid glioma

Clinical Features for Chordoid Glioma

Drugs & Therapeutics for Chordoid Glioma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Chordoid Glioma

Drug clinical trials:

Search ClinicalTrials for Chordoid Glioma

Search NIH Clinical Center for Chordoid Glioma

Search CenterWatch for Chordoid Glioma

Genetic Tests for Chordoid Glioma

Anatomical Context for Chordoid Glioma

Sources:
33MalaCards
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MalaCards organs/tissues related to Chordoid Glioma:

33
Brain, Hypothalamus

Animal Models for Chordoid Glioma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Chordoid Glioma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.0S100B, SYP, POU4F2, MUC1, GFAP, RFX3
2MP:00053917.7PTPRS, GFAP, CDK4, MUC1, POU4F2, VIM
3MP:00053847.0POU4F2, CDK4, RGS16, GFAP, KRT7, PTPRS

Publications for Chordoid Glioma

Sources:
51PubMed
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Articles related to Chordoid Glioma:

(show all 50)
idTitleAuthorsYear
1
Neuro-Ophthalmologic Features of Chordoid Glioma. (24113763)
2013
2
Therapeutic approach to chordoid glioma of the third ventricle. (23615418)
2013
3
Chordoid glioma of the third ventricle: four cases including one case with papillary features. (22716306)
2013
4
Chordoid glioma: a rare suprasellar mass. (22644806)
2012
5
Chordoid glioma in suprasellar location with extension into the third ventricle: smear preparation morphology of a rare tumor. (22246933)
2012
6
CD99 is expressed in chordoid glioma and suggests ependymal origin. (22102064)
2012
7
Cytology of chordoid glioma of the third ventricle. (22246938)
2012
8
Chordoid glioma of the third ventricle. (22754136)
2012
9
Rarest of the rare: Chordoid glioma infiltrating the optic chiasm. (21697970)
2011
10
Chordoid glioma: a case report and literature review. (21192197)
2011
11
Chordoid glioma of the third ventricle: a case report with review of literature. (21743188)
2011
12
Chordoid glioma: imaging pearls of a unique third ventricular tumor. (21059517)
2010
13
Chordoid glioma : a case report of unusual location and neuroradiological characteristics. (20717514)
2010
14
Chordoid glioma: ten years of a low-grade tumor with high morbidity. (20808539)
2010
15
Diabetes insipidus, panhypopituitarism, and severe mental status deterioration in a patient with chordoid glioma: case report and literature review. (19364693)
2009
16
Chordoid glioma with calcification and neurofilament expression: case report and review of the literature. (18262609)
2009
17
Chordoid glioma with calcification and neurofilament expression: case report and review of the literature (Iwami et al. Surg Neurol 2008;10.1016/j.surneu.2007.07.032). (19329155)
2009
18
Chordoid glioma of the third ventricle: a report of two cases, one with ultrastructural findings. (18498285)
2009
19
Chordoid glioma: a case report and molecular characterization of five cases. (18652591)
2009
20
Chordoid glioma of the third ventricle attached to the optic chiasm. Successful removal through a trans-lamina terminalis approach. (18597929)
2008
21
Chordoid glioma: report of two rare examples with unusual features. (18246456)
2008
22
Chordoid glioma of the third ventricle. (18936876)
2008
23
An incidentally detected third ventricle chordoid glioma. (18040120)
2007
24
Extraventricular unusual glioma in a child with extensive myxoid change resembling chordoid glioma. (17965223)
2007
25
Test and teach. A recurrent third ventricular brain tumour. Diagnosis: Chordoid glioma of the third ventricle. (16753749)
2006
26
Origin of chordoid glioma of the third ventricle. (16594739)
2006
27
Third ventricular chordoid glioma with unusual aggressive behavior. (17185888)
2006
28
The elusive origin of chordoid glioma. (16594734)
2006
29
Chordoid glioma of the third ventricle: Report of a case with cytologic features and utility during intraoperative consultation. (17152286)
2006
30
Chordoid glioma of the third ventricle. (16568345)
2006
31
Third ventricular chordoid glioma: clinicopathological study of two cases with evidence for a poor clinical outcome despite low grade histological features. (16008819)
2005
32
Chordoid glioma: clinicopathologic profile and differential diagnosis of an uncommon tumor. (15504076)
2004
33
Suprasellar chordoid glioma combined with Rathke's cleft cyst. (14629303)
2003
34
Immunohistochemical and ultrastructural study of chordoid glioma of the third ventricle: its tanycytic differentiation. (12748871)
2003
35
Clinicopathological and ultrastructural study in two cases of chordoid glioma. (14604300)
2003
36
Chordoid glioma: report of a case with unusual histologic features, ultrastructural study and review of the literature. (12814253)
2003
37
Third ventricular chordoid glioma: case report and review of the literature. (12765825)
2003
38
Chordoid glioma of the third ventricle: CT and MRI, including perfusion data. (12389135)
2002
39
Chordoid glioma of the third ventricle: a report of two new cases, with further evidence supporting an ependymal differentiation, and review of the literature. (12360048)
2002
40
Chordoid glioma: an uncommon tumour of the third ventricle. (11360380)
2001
41
Chordoid glioma of the third ventricle: an ultrastructural study of three cases with a histogenetic hypothesis. (11224612)
2001
42
Choroid plexus cyst and chordoid glioma. Report of two cases. (16724823)
2001
43
Chordoid glioma: a neoplasm unique to the hypothalamus and anterior third ventricle. (11237967)
2001
44
Pediatric chordoid glioma with chondroid metaplasia. (11826363)
2001
45
Chordoid glioma: a novel tumor of the third ventricle. (11149969)
2000
46
Chordoid glioma of the third ventricle: CT and MR findings. (10752904)
2000
47
Suprasellar chordoid glioma. (10867806)
2000
48
Chordoid glioma of the third ventricle: confirmatory report of a new entity. (10374785)
1999
49
Chordoid glioma of the third ventricle: immunohistochemical and molecular genetic characterization of a novel tumor entity. (10517500)
1999
50
Third ventricular chordoid glioma: a distinct clinicopathologic entity. (9600220)
1998

Genetic Variations for Chordoid Glioma

Expression for genes affiliated with Chordoid Glioma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Chordoid Glioma

Search GEO for disease gene expression data for Chordoid Glioma.

Pathways for genes affiliated with Chordoid Glioma

Sources:
38NCBI BioSystems Database
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Pathways related to Chordoid Glioma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4GFAP, CDK4, VIM

Compounds for genes affiliated with Chordoid Glioma

Sources:
45Novoseek, 11DrugBank, 24HMDB, 50PharmGKB, 29IUPHAR, 60Tocris Bioscience, 2BitterDB
See all sources

Compounds related to Chordoid Glioma according to GeneCards/GeneDecks:

(show top 50)    (show all 64)
idCompoundScoreTop Affiliating Genes
1streptozotocin4510.2GFAP, SYP
2orcein4510.1S100B, VIM
3n-acetylaspartate4510.1GFAP, SYP
42,3-cyclic nucleotide459.9GFAP, S100B
5ganglioside459.7GFAP, SYP, VIM
6alpha-latrotoxin459.7PTPRS, SYP
7catecholamine459.6SYP, S100B, VIM
8progestin459.6VIM, MUC1, CDK4
9acth459.6S100B, SYP, MUC1, GFAP
10dbc-amp459.6VIM, S100B, SYP, GFAP
11eosin459.6GFAP, MUC1, S100B, VIM
12choline45 11 2411.5VIM, S100B, SYP, GFAP
13bromodeoxyuridine459.5VIM, S100B, CDK4, GFAP
14gaba459.5GFAP, SYP, S100B, VIM
15ethanol45 50 11 2412.5S100B, SYP, MUC1, GFAP
16agar459.4VIM, MUC1, CDK4, GFAP
17paclitaxel45 50 1111.4VIM, S100B, CDK4, GFAP
18butyrate459.4VIM, MUC1, CDK4, GFAP
19valine459.4CDK4, POU4F2, S100B, VIM
20cytarabine45 50 1111.4GFAP, MUC1, VIM
21acetylcholine45 50 29 11 2413.4GFAP, SYP, S100B, VIM
225-hydroxytryptamine459.3GFAP, RGS16, SYP, VIM
23s 100459.3VIM, S100B, SYP, MUC1, GFAP
24forskolin45 50 1111.2GFAP, MUC1, SYP, S100B, VIM
25leucine459.2GFAP, CDK4, SYP, S100B, VIM
26estradiol45 11 2411.2VIM, SYP, MUC1, CDK4, GFAP
27creatinine459.2VIM, S100B, SYP, MUC1, GFAP
28matrigel459.1VIM, MUC1, GFAP, KRT7
29genistein45 29 60 2 11 2414.0VIM, SYP, CDK4, GFAP
30mucicarmine459.0VIM, S100B, SYP, MUC1, KRT7
31b 723459.0VIM, S100B, SYP, MUC1, KRT7
32cyclic amp45 2410.0VIM, S100B, SYP, MUC1, CDK4, GFAP
33dexamethasone45 50 29 1111.9VIM, S100B, SYP, MUC1, CDK4, GFAP
34iron45 249.9VIM, S100B, CDK4, GFAP, KRT7
35glutamine458.9GFAP, SYP, S100B, VIM
36alanine458.7VIM, S100B, CDK4, RGS16, GFAP
37arginine458.7VIM, S100B, CDK4, GFAP, KRT7
38reticulin458.7KRT7, GFAP, MUC1, SYP, S100B, VIM
39hematoxylin458.7VIM, S100B, SYP, MUC1, GFAP, KRT7
40formaldehyde45 249.7VIM, S100B, SYP, MUC1, GFAP, KRT7
41lipid458.5VIM, S100B, SYP, MUC1, GFAP, KRT7
42cysteine458.4VIM, S100B, SYP, MUC1, CDK4, RGS16
43glycogen45 249.4VIM, S100B, SYP, MUC1, CDK4, GFAP
44paraffin458.4VIM, S100B, SYP, MUC1, CDK4, GFAP
45progesterone45 60 29 11 2412.4VIM, S100B, SYP, MUC1, CDK4, GFAP
46testosterone45 60 11 2411.3VIM, S100B, SYP, MUC1, CDK4, GFAP
47vegf458.3VIM, S100B, SYP, MUC1, CDK4, GFAP
48retinoic acid45 249.3VIM, S100B, SYP, MUC1, CDK4, GFAP
49estrogen457.9VIM, S100B, SYP, POU4F2, MUC1, CDK4
50tyrosine457.4S100B, SYP, MUC1, CDK4, RGS16, GFAP

GO Terms for genes affiliated with Chordoid Glioma

Sources:
16Gene Ontology
See all sources

Cellular components related to Chordoid Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058829.1KRT7, GFAP, VIM

Biological processes related to Chordoid Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Bergmann glial cell differentiationGO:0600209.8VIM, GFAP
2astrocyte developmentGO:0140029.7GFAP, VIM
3negative regulation of neuron projection developmentGO:0109779.7VIM, GFAP
4intermediate filament organizationGO:0451099.6VIM, GFAP
5long-term synaptic potentiationGO:0602919.6GFAP, S100B

Products for genes affiliated with Chordoid Glioma

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Sources for Chordoid Glioma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet