MCID: CHR033
MIFTS: 39

Chordoid Glioma malady

Neuronal diseases, Cancer diseases, Rare diseases categories

Summaries for Chordoid Glioma

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MalaCards based summary: Chordoid Glioma, also known as chordoid glioma of the third ventricle, is related to third ventricle chordoid glioma and melanotic neuroectodermal tumor. An important gene associated with Chordoid Glioma is S100B (S100 calcium binding protein B), and among its related pathways are Nuclear signaling by ERBB4 and Neuroscience. The compounds n-acetylaspartate and orcein have been mentioned in the context of this disorder. Affiliated tissues include brain, thyroid and testes, and related mouse phenotypes are normal and vision/eye.

Aliases & Classifications for Chordoid Glioma

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Chordoid Glioma, Aliases & Descriptions:

Name: Chordoid Glioma 9 11 47
 
Chordoid Glioma of the Third Ventricle 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

47
chordoid glioma:
Age of onset: Adult; Age of death: adult


External Ids:

Disease Ontology9 DOID:3774
NCIt38 C5592
SNOMED-CT55 128789002
Orphanet47 251674

Related Diseases for Chordoid Glioma

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Diseases related to Chordoid Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 114)
idRelated DiseaseScoreTop Affiliating Genes
1third ventricle chordoid glioma10.7
2melanotic neuroectodermal tumor10.5SYP
3dysembryoplastic neuroepithelial tumor10.5SYP
4metanephric adenoma10.5KRT7
5choroid plexus papilloma10.5GFAP
6giant cell glioblastoma10.5GFAP
7renal cell carcinoma10.5KRT7
8nephrogenic adenoma10.5KRT7
9mixed glioma10.5GFAP
10pseudomyxoma peritonei10.5KRT7
11neurilemmoma10.5GFAP
12hidradenoma10.4MUC1
13cystadenocarcinoma10.4MUC1
14sarcoma, synovial10.4KRT7
15adenomatoid tumor10.4VIM
16subependymal giant cell astrocytoma10.4SYP, S100B
17olfactory neuroblastoma10.4SYP, S100B
18ganglioneuroblastoma10.4SYP, S100B
19myxopapillary ependymoma10.4GFAP, S100B
20choroid plexus carcinoma10.3GFAP, S100B
21binswanger's disease10.3GFAP, SYP
22gemistocytic astrocytoma10.3GFAP, S100B
23central neurocytoma10.3GFAP, SYP
24fibrous meningioma10.3MUC1, S100B
25amyotrophic lateral sclerosis 110.3SYP, GFAP
26mammary paget's disease10.3MUC1, KRT7
27mucinous cystadenocarcinoma10.3MUC1, KRT7
28sertoli-leydig cell tumor10.3MUC1, KRT7
29paget disease, extramammary10.3KRT7, MUC1
30anaplastic oligodendroglioma10.3GFAP, CDK4
31glomus tumor10.3VIM, SYP
32merkel cell carcinoma10.3MUC1, SYP
33brain cancer10.3SYP, GFAP
34gliosarcoma10.3GFAP, CDK4
35papillary ependymoma10.2GFAP, SYP, S100B
36adenosquamous carcinoma10.2MUC1, KRT7
37pineocytoma10.2GFAP, SYP, S100B
38fibrous histiocytoma10.2VIM, S100B
39ganglioglioma10.2GFAP, SYP, S100B
40mucoepidermoid carcinoma10.2MUC1, KRT7
41ganglioneuroma10.2S100B, SYP, GFAP
42rhabdoid meningioma10.2GFAP, VIM
43paraganglioma10.2GFAP, SYP, S100B
44large cell carcinoma10.2SYP, KRT7, CDK4
45diabetes insipidus10.2
46choroiditis10.2
47thyroiditis10.2
48choroid plexus cyst10.2
49astroblastoma10.2GFAP, VIM
50endometrial cancer10.2KRT7, MUC1

Graphical network of the top 20 diseases related to Chordoid Glioma:



Diseases related to chordoid glioma

Symptoms for Chordoid Glioma

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Drugs & Therapeutics for Chordoid Glioma

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Drug clinical trials:

Search ClinicalTrials for Chordoid Glioma

Search NIH Clinical Center for Chordoid Glioma

Genetic Tests for Chordoid Glioma

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Anatomical Context for Chordoid Glioma

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MalaCards organs/tissues related to Chordoid Glioma:

31
Brain, Thyroid, Testes, Hypothalamus

Animal Models for Chordoid Glioma or affiliated genes

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MGI Mouse Phenotypes related to Chordoid Glioma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.7S100B, SYP, MUC1, RFX3, GFAP
2MP:00053918.5CDK4, MUC1, VIM, PTPRS, GFAP
3MP:00053867.8GFAP, PTPRS, VIM, S100B, RGS16, CDK4
4MP:00053847.1GFAP, PTPRS, VIM, RGS16, KRT7, CDK4

Publications for Chordoid Glioma

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Articles related to Chordoid Glioma:

(show top 50)    (show all 51)
idTitleAuthorsYear
1
Expression of thyroid transcription factor 1 in a chordoid glioma. (25248954)
2014
2
Neuro-Ophthalmologic Features of Chordoid Glioma. (24113763)
2013
3
Therapeutic approach to chordoid glioma of the third ventricle. (23615418)
2013
4
Chordoid glioma of the third ventricle: four cases including one case with papillary features. (22716306)
2013
5
Chordoid glioma: a rare suprasellar mass. (22644806)
2012
6
CD99 is expressed in chordoid glioma and suggests ependymal origin. (22102064)
2012
7
Cytology of chordoid glioma of the third ventricle. (22246938)
2012
8
Chordoid glioma of the third ventricle. (22754136)
2012
9
Rarest of the rare: Chordoid glioma infiltrating the optic chiasm. (21697970)
2011
10
Chordoid glioma: a case report and literature review. (21192197)
2011
11
Chordoid glioma of the third ventricle: a case report with review of literature. (21743188)
2011
12
Chordoid glioma: imaging pearls of a unique third ventricular tumor. (21059517)
2010
13
Chordoid glioma : a case report of unusual location and neuroradiological characteristics. (20717514)
2010
14
Chordoid glioma: ten years of a low-grade tumor with high morbidity. (20808539)
2010
15
Diabetes insipidus, panhypopituitarism, and severe mental status deterioration in a patient with chordoid glioma: case report and literature review. (19364693)
2009
16
Chordoid glioma with calcification and neurofilament expression: case report and review of the literature. (18262609)
2009
17
Chordoid glioma with calcification and neurofilament expression: case report and review of the literature (Iwami et al. Surg Neurol 2008;10.1016/j.surneu.2007.07.032). (19329155)
2009
18
Chordoid glioma of the third ventricle: a report of two cases, one with ultrastructural findings. (18498285)
2009
19
Chordoid glioma: a case report and molecular characterization of five cases. (18652591)
2009
20
Chordoid glioma of the third ventricle attached to the optic chiasm. Successful removal through a trans-lamina terminalis approach. (18597929)
2008
21
Chordoid glioma: report of two rare examples with unusual features. (18246456)
2008
22
Chordoid glioma of the third ventricle. (18936876)
2008
23
An incidentally detected third ventricle chordoid glioma. (18040120)
2007
24
Extraventricular unusual glioma in a child with extensive myxoid change resembling chordoid glioma. (17965223)
2007
25
Test and teach. A recurrent third ventricular brain tumour. Diagnosis: Chordoid glioma of the third ventricle. (16753749)
2006
26
Origin of chordoid glioma of the third ventricle. (16594739)
2006
27
Third ventricular chordoid glioma with unusual aggressive behavior. (17185888)
2006
28
The elusive origin of chordoid glioma. (16594734)
2006
29
Chordoid glioma of the third ventricle: Report of a case with cytologic features and utility during intraoperative consultation. (17152286)
2006
30
Chordoid glioma of the third ventricle. (16568345)
2006
31
Third ventricular chordoid glioma: clinicopathological study of two cases with evidence for a poor clinical outcome despite low grade histological features. (16008819)
2005
32
Chordoid glioma: clinicopathologic profile and differential diagnosis of an uncommon tumor. (15504076)
2004
33
Suprasellar chordoid glioma combined with Rathke's cleft cyst. (14629303)
2003
34
Immunohistochemical and ultrastructural study of chordoid glioma of the third ventricle: its tanycytic differentiation. (12748871)
2003
35
Clinicopathological and ultrastructural study in two cases of chordoid glioma. (14604300)
2003
36
Chordoid glioma: report of a case with unusual histologic features, ultrastructural study and review of the literature. (12814253)
2003
37
Third ventricular chordoid glioma: case report and review of the literature. (12765825)
2003
38
Chordoid glioma of the third ventricle: CT and MRI, including perfusion data. (12389135)
2002
39
Chordoid glioma of the third ventricle: a report of two new cases, with further evidence supporting an ependymal differentiation, and review of the literature. (12360048)
2002
40
Chordoid glioma: an uncommon tumour of the third ventricle. (11360380)
2001
41
Chordoid glioma of the third ventricle: an ultrastructural study of three cases with a histogenetic hypothesis. (11224612)
2001
42
Choroid plexus cyst and chordoid glioma. Report of two cases. (16724823)
2001
43
Chordoid glioma: a neoplasm unique to the hypothalamus and anterior third ventricle. (11237967)
2001
44
Pediatric chordoid glioma with chondroid metaplasia. (11826363)
2001
45
Chordoid glioma: a novel tumor of the third ventricle. (11149969)
2000
46
Chordoid glioma of the third ventricle: CT and MR findings. (10752904)
2000
47
Suprasellar chordoid glioma. (10867806)
2000
48
Chordoid glioma of the third ventricle: confirmatory report of a new entity. (10374785)
1999
49
Chordoid glioma of the third ventricle: immunohistochemical and molecular genetic characterization of a novel tumor entity. (10517500)
1999
50
Third ventricular chordoid glioma: a distinct clinicopathologic entity. (9600220)
1998

Variations for Chordoid Glioma

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Expression for genes affiliated with Chordoid Glioma

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Search GEO for disease gene expression data for Chordoid Glioma.

Pathways for genes affiliated with Chordoid Glioma

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Pathways related to Chordoid Glioma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.8GFAP, S100B
29.5S100B, GFAP, SYP
39.4GFAP, VIM, CDK4
49.2VIM, KRT7

Compounds for genes affiliated with Chordoid Glioma

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Compounds related to Chordoid Glioma according to GeneCards Suite gene sharing:

(show top 50)    (show all 82)
idCompoundScoreTop Affiliating Genes
1n-acetylaspartate439.9SYP, GFAP
2orcein439.9VIM, S100B
3alpha-latrotoxin439.8PTPRS, SYP
4streptozotocin439.7SYP, VIM, GFAP
5ganglioside439.6SYP, GFAP, VIM
6acth439.5GFAP, MUC1, SYP, S100B
7dbc-amp439.5SYP, VIM, GFAP, S100B
8ethanol43 49 24 1212.5S100B, GFAP, MUC1, SYP
9progestin439.5MUC1, VIM, CDK4
10choline43 24 1211.5S100B, GFAP, VIM, SYP
11eosin439.5S100B, VIM, GFAP, MUC1
12bromodeoxyuridine439.5S100B, VIM, CDK4, GFAP
13catecholamine439.4VIM, S100B, SYP
14gaba439.4S100B, SYP, VIM, GFAP
15paclitaxel43 49 1211.4GFAP, VIM, CDK4, S100B
16acetylcholine43 49 28 24 1213.4VIM, S100B, GFAP, SYP
17agar439.3MUC1, VIM, GFAP, CDK4
18cytarabine43 49 1211.3MUC1, VIM, GFAP
19butyrate439.3MUC1, CDK4, VIM, GFAP
20s 100439.2SYP, MUC1, VIM, GFAP, S100B
21leucine439.1CDK4, S100B, SYP, GFAP, VIM
225-hydroxytryptamine439.1GFAP, SYP, VIM, RGS16
23genistein43 28 59 2 24 1214.1GFAP, VIM, CDK4, SYP
24forskolin43 49 1211.1SYP, VIM, MUC1, S100B, GFAP
25creatinine439.1SYP, S100B, MUC1, VIM, GFAP
26estradiol43 24 1211.1SYP, GFAP, VIM, MUC1, CDK4
27glutamine439.0SYP, GFAP, S100B, VIM
28matrigel438.8VIM, MUC1, KRT7, GFAP
29cyclic amp43 249.8VIM, CDK4, S100B, SYP, MUC1, GFAP
30dexamethasone43 49 28 1211.8VIM, GFAP, MUC1, S100B, SYP, CDK4
31alanine438.7CDK4, S100B, VIM, GFAP, RGS16
32mucicarmine438.7VIM, MUC1, SYP, S100B, KRT7
33b 723438.7KRT7, VIM, SYP, MUC1, S100B
34iron43 249.6GFAP, VIM, S100B, CDK4, KRT7
35serine438.6S100B, SYP, MUC1, VIM, GFAP, CDK4
36arginine438.5CDK4, KRT7, S100B, VIM, GFAP
37reticulin438.3MUC1, KRT7, S100B, SYP, GFAP, VIM
38hematoxylin438.3SYP, GFAP, VIM, MUC1, S100B, KRT7
39formaldehyde43 249.3SYP, GFAP, S100B, VIM, KRT7, MUC1
40lipid438.2VIM, SYP, S100B, KRT7, MUC1, GFAP
41cysteine438.2CDK4, VIM, MUC1, SYP, GFAP, S100B
42glucose438.0CDK4, GFAP, MUC1, S100B, KRT7
43glycogen43 249.0CDK4, S100B, KRT7, SYP, GFAP, VIM
44paraffin438.0CDK4, S100B, SYP, GFAP, VIM, MUC1
45progesterone43 28 59 24 1212.0CDK4, GFAP, VIM, SYP, MUC1, KRT7
46testosterone43 59 24 1211.0CDK4, MUC1, VIM, S100B, SYP, KRT7
47vegf438.0VIM, GFAP, SYP, MUC1, KRT7, S100B
48estrogen438.0KRT7, S100B, GFAP, VIM, MUC1, CDK4
49retinoic acid43 249.0GFAP, VIM, SYP, S100B, MUC1, KRT7
50tyrosine437.3CDK4, MUC1, KRT7, RGS16, SYP, PTPRS

GO Terms for genes affiliated with Chordoid Glioma

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Cellular components related to Chordoid Glioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058828.9KRT7, VIM, GFAP

Biological processes related to Chordoid Glioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of neuronal synaptic plasticityGO:00481689.8SYP, S100B
2Bergmann glial cell differentiationGO:00600209.8VIM, GFAP
3astrocyte developmentGO:00140029.7VIM, GFAP
4intermediate filament organizationGO:00451099.7VIM, GFAP
5negative regulation of neuron projection developmentGO:00109779.7VIM, GFAP
6long-term synaptic potentiationGO:00602919.5S100B, GFAP

Molecular functions related to Chordoid Glioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00055156.6CDK4, KRT7, RGS16, S100B, MUC1, RFX3

Products for genes affiliated with Chordoid Glioma

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Sources for Chordoid Glioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet