MCID: CHR005
MIFTS: 56

Chorioamnionitis malady

Summaries for Chorioamnionitis

About this section
Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Disease Ontology:8 A placenta disease that is an inflammation of the fetal membranes (amnion and chorion) due to a bacterial infection.

MalaCards: Chorioamnionitis is related to funisitis and cerebral palsy. An important gene associated with Chorioamnionitis is MMP8 (matrix metallopeptidase 8 (neutrophil collagenase)), and among its related pathways are Monoamine Transport and TGF-Beta Pathway. The compounds tenidap and endotoxin have been mentioned in the context of this disorder. Affiliated tissues include placenta, uterus and lung, and related mouse phenotypes are tumorigenesis and skeleton.

Wikipedia:63 Chorioamnionitis is an inflammation of the fetal membranes (amnion and chorion) due to a bacterial... more...

Aliases & Classifications for Chorioamnionitis

About this section
Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS
See all sources

Aliases & Descriptions:

chorioamnionitis 8 10 44 60


External Ids:

Disease Ontology8 DOID:0050697

Related Diseases for Chorioamnionitis

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Chorioamnionitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 237)
idRelated DiseaseScoreTop Affiliating Genes
1funisitis30.8MMP8
2cerebral palsy30.5MMP8
3pre-eclampsia30.2PTX3, IL6, OXT, FLT1, TLR4
4appendicitis30.1CRP
5hepatitis30.1TLR2
6hypertension29.8CRP
7influenza29.8LTF
8bacteriuria29.8CRP
9malaria29.8TNF, TLR2
10retinopathy of prematurity29.8FLT1
11otitis media29.8IL1B, LTF, TLR2
12crohn's disease29.8LTF, CRP, TNF
13bacterial vaginosis29.8IL1B, IL8, IL1R1, LTF
14respiratory failure29.8IL6, IL1B, CRP, TNF
15placental insufficiency29.8FLT1
16endometriosis29.8IL6, IL1B, IL8, IL1R1, OXTR, FLT1
17vasculitis29.8ELANE, PTX3, LTF, CRP, TNF, S100A12
18pneumonia29.8ELANE, MMP8, IL6, IL1B, IL8, CRP
19asthma29.8ELANE, MMP8, IL1B, IL8, FLT1, TNF
20cerebritis10.4
21vaginitis10.3
22cervicitis10.2
23endometritis10.2
24eclampsia10.1
25placental abruption10.1
26leukemoid reaction10.0
27aortic aneurysm10.0CRP
28osteomyelitis10.0CRP
29rhinitis10.0IL8
30amyloidosis10.0CRP
31irritable bowel syndrome10.0LTF
32leprosy10.0TLR2
33pleurisy10.0IL1B
34multiple myeloma10.0IL6
35rheumatic fever10.0CRP
36hypercholesterolemia10.0CRP
37ischemia10.0FLT1
38bronchiolitis obliterans10.0MMP8, IL8
39septic arthritis10.0CRP
40peptic ulcer10.0IL8
41gastric ulcer10.0TLR2
42acute pyelonephritis10.0CRP
43gingival overgrowth10.0IL1B
44kaposi's sarcoma10.0IL6
45bronchiolitis10.0IL8, TLR4
46herpes simplex10.0TLR2
47measles10.0TLR2
48diabetic retinopathy10.0FLT1
49myopathy10.0CRP
50prostatitis10.0LTF

Graphical network of the top 20 diseases related to Chorioamnionitis:



Diseases related to chorioamnionitis

Clinical Features for Chorioamnionitis

About this section

Drugs & Therapeutics for Chorioamnionitis

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Chorioamnionitis

Drug clinical trials:

Search ClinicalTrials for Chorioamnionitis

Search NIH Clinical Center for Chorioamnionitis

Search CenterWatch for Chorioamnionitis

Genetic Tests for Chorioamnionitis

About this section

Anatomical Context for Chorioamnionitis

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Chorioamnionitis:

32
Placenta, Uterus, Lung, Brain, Colon, Endothelial, Fetal lung, Monocytes, Thymus, Heart, Fetal brain, T cells, Testes, Skin, Spleen, Bone, Bone marrow

Animal Models for Chorioamnionitis or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Chorioamnionitis:

36 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000200610.4TNF, IL1R1, IL1B, IL6, MMP8, ELANE
2MP:000539010.4IL6, IL1B
3MP:000536910.3TLR4, TLR2, FLT1, OXTR, RAMP2
4MP:001077110.3TLR4, TLR2, OXTR, OXT, IL1R1, IL6
5MP:000537610.1TLR4, TLR2, CRP, OXT, LTF, HPGD
6MP:000538910.1TLR4, FLT1, OXTR, OXT, IL1RN, RAMP2
7MP:000539710.1TLR4, TLR2, TNF, FLT1, LTF, IL1RN
8MP:000538510.0TLR4, TLR2, TNF, CRP, FLT1, OXT
9MP:000537910.0TLR2, TNF, OXTR, OXT, HPGD, IL1R1
10MP:000537010.0TLR4, TLR2, TNF, LTF, IL1R1, IL6
11MP:00036319.9RAMP2, OXT, OXTR, TLR4
12MP:00053879.9ELANE, TLR4, TLR2, TNF, CRP, FLT1
13MP:00107689.8TLR4, TLR2, TNF, FLT1, OXT, HPGD

Publications for Chorioamnionitis

About this section
Sources:
50PubMed
See all sources

Articles related to Chorioamnionitis:

(show top 50)    (show all 524)
idTitleAuthorsYear
1
Prolidase, matrix metalloproteinases 1 and 13 activity, oxidative-antioxidative status as a marker of preterm premature rupture of membranes and chorioamnionitis in maternal vaginal washing fluids. (23983595)
2013
2
Chorioamnionitis without foetal inflammatory response is associated with stillbirth in early preterm pregnancies. (23339524)
2013
3
Histologic chorioamnionitis is associated with reduced risk of late-onset sepsis in preterm infants. (22157134)
2012
4
White matter injury following fetal inflammatory response syndrome induced by chorioamnionitis and fetal sepsis: lessons from experimental ovine models. (23078831)
2012
5
Chorioamnionitis as a risk factor for bronchopulmonary dysplasia: a systematic review and meta-analysis. (21697236)
2012
6
Is chorioamnionitis harmful for the brain of preterm infants? A clinical overview. (22230024)
2012
7
Urinary A92-microglobulin in very preterm neonates with chorioamnionitis. (21667058)
2011
8
When the womb is no longer safe: chorioamnionitis. (21999053)
2011
9
Amniotic fluid concentrations of soluble scavenger receptor for hemoglobin (sCD163) in pregnancy complicated by preterm premature rupture of the membranes and histologic chorioamnionitis. (21158489)
2011
10
The impact of clinical maternal chorioamnionitis on neurological and psychological sequelae in very-low-birth weight infants: a case-control study. (21299358)
2011
11
The risk of intra-amniotic infection, inflammation and histologic chorioamnionitis in term pregnant women with intact membranes and labor. (21565402)
2011
12
Funisitis and chorionic vasculitis: relation to chorioamnionitis, timing and scoring. (22059462)
2011
13
Magnetic resonance imaging demonstrates long-term changes in brain structure in children born preterm and exposed to chorioamnionitis. (21987595)
2011
14
Maternal interleukin-6 (-174) C/C polymorphism is associated with chorioamnionitis and cystic periventricular leucomalacia of the preterm infant. (20237486)
2010
15
The frequency, clinical significance, and pathological features of chronic chorioamnionitis: a lesion associated with spontaneous preterm birth. (20348884)
2010
16
Chorioamnionitis and mid-trimester pregnancy loss. (21051848)
2010
17
Clinical significance of singleton pregnancies complicated by placental abruption associated with histological chorioamnionitis. (20818138)
2010
18
Chorioamnionitis: a multiorgan disease of the fetus? (20877404)
2010
19
The involvement of human amnion in histologic chorioamnionitis is an indicator that a fetal and an intra-amniotic inflammatory response is more likely and severe: clinical implications. (19046766)
2009
20
Eikenella corrodens chorioamnionitis: modes of infection? (19114269)
2009
21
Fetal umbilical cord blood erythropoietin, interleukin-6, pH, pO(2), pCO(2), and base excess levels in histologic and/or clinical chorioamnionitis: is the response only inflammatory? (19842878)
2009
22
Diffusion MRI brain findings in neonates exposed to chorioamnionitis: a case series. (19646314)
2009
23
Value of amniotic fluid interleukin-8 for the prediction of histological chorioamnionitis in preterm premature rupture of membranes. (20038922)
2009
24
Accuracy of C-reactive protein determination in predicting chorioamnionitis and neonatal infection in pregnant women with premature rupture of membranes: a systematic review. (19819609)
2009
25
Intrapartum fever and chorioamnionitis as risks for encephalopathy in term newborns: a case-control study. (18173624)
2008
26
Impact on neonatal outcome and anthropometric growth in very low birth weight infants with histological chorioamnionitis. (18445544)
2008
27
Use of C-reactive protein as a predictor of chorioamnionitis in preterm prelabour rupture of membranes: a systematic review. (17567416)
2007
28
The value of cord blood interleukin-6 levels for predicting chorioamnionitis, funisitis and neonatal infection in term premature rupture of membranes. (16459014)
2006
29
Transient hypothyroxinemia of prematurity and histological chorioamnionitis. (16318614)
2005
30
Chorioamnionitis is associated with increased CD40L expression on cord blood platelets. (16411397)
2005
31
Facklamia hominis causing chorioamnionitis and puerperal bacteraemia. (15845436)
2005
32
Polymorphisms in immunoregulatory genes and the risk of histologic chorioamnionitis in Caucasoid women: a case control study. (15723707)
2005
33
Depression at birth in term infants exposed to maternal chorioamnionitis: does neonatal fever play a role? (15858605)
2005
34
Chorioamnionitis and labor. (15899361)
2005
35
Interleukin-6 and interleukin-8 are elevated in the cerebrospinal fluid of infants exposed to chorioamnionitis. (15983435)
2005
36
Histologic chorioamnionitis and severity of illness in very low birth weight newborns. (15857528)
2005
37
Early postnatal skin colour changes in term newborns with subclinical histological chorioamnionitis. (15241686)
2004
38
Chorioamnionitis increases matrix metalloproteinase-8 concentrations in bronchoalveolar lavage fluid from preterm babies. (14711859)
2004
39
Development of a guinea pig model of chorioamnionitis and fetal brain injury. (15507942)
2004
40
Are complete blood cell counts useful in the evaluation of asymptomatic neonates exposed to suspected chorioamnionitis? (15121926)
2004
41
Induction of hepatic granulopoiesis due to chorioamnionitis during the second trimester of development. (12969577)
2003
42
Histologic chorioamnionitis and umbilical serum levels of pro-inflammatory cytokines and cytokine inhibitors. (12066943)
2002
43
Chorioamnionitis and brain injury. (12516738)
2002
44
Campylobacter fetus subspecies fetus bacteremia associated with chorioamnionitis and intact fetal membranes. (11233847)
2001
45
NAD(P)H oxidase in human fetal membrane chorion laeve trophoblasts with or without chorioamnionitis: ultrastructural enzyme histochemical study. (11470866)
2001
46
Case of chorioamnionitis in an immunocompetent woman caused by Morganella morganii. (9502663)
1998
47
Methicillin resistant Staphylococcus aureus as a cause of chorioamnionitis. (9987566)
1998
48
Is there an association between water baths during labor and the development of chorioamnionitis or endometritis? (9662304)
1998
49
Cytokine expression in the placenta. The role of interleukin 1 and interleukin 1 receptor antagonist expression in chorioamnionitis and parturition. (7506905)
1994
50
Clinical evaluation of flomoxef in the treatment of chorioamnionitis and changes in the fetal fibronectin level in vaginal secretion]. (8331777)
1993

Genetic Variations for Chorioamnionitis

About this section

Expression for genes affiliated with Chorioamnionitis

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Chorioamnionitis

Search GEO for disease gene expression data for Chorioamnionitis.

Pathways for genes affiliated with Chorioamnionitis

About this section
Sources:
37NCBI BioSystems Database, 51QIAGEN, 52R&D Systems, 29KEGG, 12EMD Millipore, 53Reactome, 59Tocris Bioscience, 4Cell Signaling Technology
See all sources

Pathways related to Chorioamnionitis according to GeneCards/GeneDecks:

(show top 50)    (show all 53)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.4IL1R1
2
Hide members
10.4FLT1
3
Hide members
10.4IL6, IL1R1
4
Hide members
10.4TLR2, TLR4
510.4TLR2, TLR4
610.4TLR4, TLR2
7
Hide members
10.4IL1R1, FLT1
8
Hide members
10.4FLT1, TLR4
9
Cytokine production by Th17 cells in CF (Mouse model)
10.3TLR4, IL8, IL6
1010.3IL8, TNF, IL6
1110.3MMP8, ELANE, LTF
1210.3TNF, IL6, ELANE
1310.3IL1B, TNF, IL6
1410.3TNF, IL1B, IL6
15
Hide members
10.3IL1R1, IL1B, IL1RN
1610.3IL1R1, TLR4, TNF
1710.3TLR4, IL6, IL1B, IL8
1810.3IL6, TLR4, TLR2, IL8
1910.3IL1B, IL6, TLR2, IL8
20
Hide members
10.3TNF, IL1B, IL6, IL8
2110.3IL6, IL1B, IL8, TNF
2210.3CRP, IL6, TNF, IL1B
23
Hide members
10.3IL1R1, IL1RN, IL1B, IL6
2410.3IL1B, IL6, IL1R1, TNF
2510.3TNF, TLR4, IL6, IL1B
26
Hide members
10.3TLR4, IL1R1, IL1B, TLR2
2710.3IL6, TLR4, TLR2, TNF
28
Hide members
10.3TLR4, TNF, IL1R1, IL1B
2910.2TLR4, IL1B, TNF, TLR2
3010.2TLR4, TLR2, IL1B, TNF
3110.2ELANE, IL8, IL6, HPGD, FLT1
3210.2TNF, IL1B, IL8, TLR4, IL6
3310.2IL1R1, IL1B, TLR4, TNF, IL8
3410.2IL6, IL1B, IL8, IL1RN, TNF
3510.2IL6, IL1B, TNF, TLR4, IL1R1
36
Hide members
10.2IL6, IL1B, TNF, TLR2, TLR4
3710.2TLR4, TLR2, IL6, TNF, IL1B
38
Hide members
10.2IL1R1, TNF, TLR2, IL1B, TLR4
39
Hide members
10.2TLR4, TLR2, IL1R1, IL1B, TNF
40
Hide members
10.2IL1B, OXT, IL6, RAMP2, OXTR
41
Hide members
10.2IL8, IL6, IL1B, TNF, TLR4, IL1R1
42
Hide members
10.2TLR2, TNF, IL8, IL1B, IL6, TLR4
43
Hide members
10.2TLR4, IL6, TLR2, TNF, IL8, IL1B
4410.2IL6, IL8, TLR2, IL1B, TLR4, TNF
4510.1TLR4, TNF, IL1R1, IL8, IL1B, IL6
46
Hide members
10.1TNF, IL1R1, TLR2, IL8, IL1B, TLR4
47
Hide members
10.1IL1B, IL1R1, FLT1, TNF, TLR4, TLR2
48
Immune response Bacterial infections in normal airways
Hide members
10.0IL8, IL6, IL1B, IL1R1, IL1RN, TNF
49
Hide members
10.0IL6, IL1B, IL8, FLT1, IL1R1, TLR4
50
Hide members
10.0TLR4, IL6, IL1B, TLR2, S100A12, IL1R1

Compounds for genes affiliated with Chorioamnionitis

About this section
Sources:
44Novoseek, 28IUPHAR, 2BitterDB, 59Tocris Bioscience, 11DrugBank, 24HMDB, 49PharmGKB
See all sources

Compounds related to Chorioamnionitis according to GeneCards/GeneDecks:

(show top 50)    (show all 210)
idCompoundScoreTop Affiliating Genes
1tenidap44 2811.8LTF, IL1R1
2endotoxin4410.8LTF, HPGD
3gabexate mesilate4410.8ELANE
4cycloheximide4410.8TLR2
5hydrocortisone44 2 59 1113.7FLT1, LTF, IL8, ELANE
6pentoxifylline44 1111.7LTF, IL1RN, IL1R1, ELANE
7cyclosporin a44 28 5912.6LTF, IL1R1, MMP8, ELANE
8h2o24410.6MMP8, FLT1, LTF, IL1RN, IL1R1
9anakinra44 1111.6IL1RN, IL1R1, IL1B, CRP, IL6, TNF
10superoxide44 2411.6MMP8, IL1B, LTF, TNF, ELANE
11hbd24410.5IL8, TLR4, TLR2, DEFB103B, IL1B, IL6
12prostaglandin4410.5IL1B, IL1R1, TNF, OXTR, HPGD, IL1RN
13indomethacin44 59 28 1113.5HPGD, IL1R1, OXTR, LTF
14gold sodium thiomalate4410.5IL8, IL1R1, TNF, IL1RN, IL1B
15sulfasalazine44 28 49 1113.5IL1RN, IL1B, CRP, IL1R1, IL8, TNF
16etanercept44 49 1112.5IL6, IL1R1, IL1RN, CRP, IL8, TNF
17zymosan4410.5TLR2, TNF, TLR4, LTF, IL1RN, ELANE
18polyinosinic-polycytidylic acid4410.5TLR2, IL8, IL1B, IL6, TLR4, TNF
19infliximab44 49 1112.5IL6, IL1R1, IL1RN, CRP, IL1B, TLR4
20peptidoglycan44 2811.5IL1RN, IL1R1, IL8, IL1B, IL6, TNF
21lipoteichoic acid4410.5TLR4, TLR2, TNF, IL1RN, IL1R1, IL8
22il 104410.5IL1RN, TNF, TLR2, TLR4, IL1R1, IL8
23polymyxin b4410.5IL6, TLR2, TNF, LTF, IL1RN, TLR4
24poly(i-c)4410.5TLR4, TNF, IL1B, IL6, TLR2, IL8
25ivig4410.5S100A12, TNF, IL1RN, IL1R1, IL6, CRP
26adalimumab44 49 1112.5TNF, CRP, IL1RN, IL1R1, IL6
27ccl344 2811.5IL1R1, IL8, TNF, IL1B, IL6, PTX3
28rantes4410.4IL1R1, TLR2, IL1B, IL6, TNF, TLR4
29neopterin4410.4ELANE, IL6, IL1B, IL8, IL1R1, IL1RN
30il-124410.4IL8, IL6, IL1B, TNF, IL1R1
31leukotriene b444 59 2412.4ELANE, TLR2, LTF, HPGD, IL1RN, IL1R1
32fibrinogen4410.3IL1RN, IL6, IL1R1, MMP8, ELANE, LTF
33n acetylcysteine4410.3IL6, IL1R1, TLR4, TNF, CRP, IL1B
34sb 20358044 5911.3IL6, TLR2, IL1R1, IL8, TNF, IL1RN
35simvastatin44 49 59 28 11 2415.3IL6, TLR4, TLR2, TNF, CRP, IL1RN
36imiquimod44 28 59 1113.3TLR4, TLR2, IL6, IL8, TNF
37lactate4410.3TLR4, ELANE, MMP8, IL6, IL8, IL1R1
38dexamethasone44 49 28 1113.3PTX3, RAMP2, IL6, IL1R1, HPGD, OXTR
39fmlp4410.3IL1RN, ELANE, LTF
40actinomycin d4410.3IL1R1, PTX3, IL6, IL1B, IL8, LTF
41hyaluronic acid44 2411.3ELANE, IL1RN, IL1R1, IL8, IL1B, LTF
42leflunomide49 44 1112.2TNF, IL1R1, IL6, IL1RN, IL1B
43polysulfone4410.2IL1RN, ELANE, IL1R1, IL1B
44nitric oxide44 11 2412.2IL1R1, IL6, FLT1, IL8, OXT, IL1B
45vegf4410.1LTF, OXT, OXTR, FLT1, TNF, TLR2
46serine4410.1LTF, OXT, FLT1, TNF, IL8, TLR2
47histamine44 28 2412.1TLR4, TLR2, TNF, LTF, IL1RN, IL1B
48retinoic acid44 2411.1OXT, TLR4, TLR2, TNF, LTF, IL1RN
49cysteine4410.0DEFB103B, TLR2, TLR4, IL8, IL1R1, OXT
50alanine449.7LTF, HPGD, IL1RN, IL1R1, IL6, OXTR

GO Terms for genes affiliated with Chorioamnionitis

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Chorioamnionitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1secretory granuleGO:03014110.3OXT, LTF, IL1B, ELANE
2cell surfaceGO:00998610.2TLR2, TNF, IL1R1, RAMP2, ELANE
3extracellular spaceGO:00561510.1TNF, CRP, FLT1, OXT, IL1RN, IL8
4integral to plasma membraneGO:00588710.0TLR4, TLR2, TNF, FLT1, OXTR, IL1R1
5external side of plasma membraneGO:00989710.0TLR4, TLR2, TNF, IL6
6extracellular regionGO:0055769.9ELANE, S100A12, TNF, CRP, OXT, LTF
7plasma membraneGO:0058869.9TLR2, S100A12, TNF, CRP, FLT1, OXTR

Biological processes related to Chorioamnionitis according to GeneCards/GeneDecks:

(show top 50)    (show all 57)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of chemokine biosynthetic processGO:04507910.8ELANE, IL6
2positive regulation of norepinephrine secretionGO:01070110.8OXT, OXTR
3negative regulation of lipid storageGO:01088810.8TNF, IL6, CRP
4chronic inflammatory response to antigenic stimulusGO:00243910.7IL1RN, TNF
5positive regulation of calcidiol 1-monooxygenase activityGO:06055910.7IL1B, TNF
6sequestering of triglycerideGO:03073010.7IL1B, TNF
7positive regulation of interleukin-8 biosynthetic processGO:04541610.7TLR4, ELANE, TNF
8positive regulation of interleukin-8 productionGO:03275710.7TLR4, IL1B, TLR2
9negative regulation of growth of symbiont in hostGO:04413010.7TLR2, TNF, ELANE
10monocyte chemotaxisGO:00254810.7S100A12, FLT1, IL6
11positive regulation of penile erectionGO:06040610.7OXT, OXTR
12positive regulation of chemokine productionGO:03272210.7TLR4, TLR2, IL6, TNF
13acute-phase responseGO:00695310.7IL6, CRP, IL1RN
14defense response to Gram-positive bacteriumGO:05083010.7TNF, CRP, IL6, TLR2
15positive regulation of interferon-gamma productionGO:03272910.7IL1B, TNF, TLR4
16positive regulation of heterotypic cell-cell adhesionGO:03411610.7IL1B, TNF
17response to progesterone stimulusGO:03257010.7RAMP2, OXTR, OXT
18positive regulation of NF-kappaB import into nucleusGO:04234610.7TLR4, TNF, TLR2, IL1B
19response to yeastGO:00187810.7PTX3, ELANE
20negative regulation of gastric acid secretionGO:06045510.7OXT, OXTR
21lipopolysaccharide-mediated signaling pathwayGO:03166310.7TNF, IL1B, TLR4, TLR2
22neutrophil chemotaxisGO:03059310.7IL1B, IL8, S100A12
23positive regulation of smooth muscle cell proliferationGO:04866110.7ELANE, IL6, TNF
24humoral immune responseGO:00695910.7IL6, TNF, LTF
25response to glucocorticoid stimulusGO:05138410.7IL1RN, OXT, IL6, TNF
26positive regulation of MAP kinase activityGO:04340610.6TNF, S100A12, ELANE, FLT1
27positive regulation of interleukin-6 productionGO:03275510.6IL6, TLR4, TLR2, TNF, IL1B
28positive regulation of fever generationGO:03162210.6TNF, IL1B
29sperm ejaculationGO:04271310.6OXTR, OXT
30female pregnancyGO:00756510.6IL1RN, OXTR, RAMP2, HPGD, OXT
31memoryGO:00761310.6IL1RN, OXT, OXTR
32positive regulation of prostaglandin secretionGO:03230810.6OXT, IL1B
33positive regulation of macrophage cytokine productionGO:06090710.6TLR4, TLR2
34positive regulation of I-kappaB kinase/NF-kappaB cascadeGO:04312310.6LTF, IL1B, S100A12, TNF, TLR4
35positive regulation of inflammatory responseGO:05072910.6TLR4, TLR2, S100A12
36positive regulation of JNK cascadeGO:04633010.6TLR4, IL1B, TNF
37positive regulation of nitric oxide biosynthetic processGO:04542910.6TLR2, TLR4, TNF, IL1B, IL6, PTX3
38immune responseGO:00695510.6IL8, IL1B, IL1R1, IL1RN, TLR2, TLR4
39cellular response to lipoteichoic acidGO:07122310.6TLR2, TLR4
40epithelial cell proliferation involved in salivary gland morphogenesisGO:06066410.5TNF, IL6
41positive regulation of NF-kappaB transcription factor activityGO:05109210.5TLR2, TNF, IL6, S100A12, TLR4, LTF
42response to estradiol stimulusGO:03235510.5OXTR, RAMP2, OXT
43opsonizationGO:00822810.5PTX3, CRP
44maternal behaviorGO:04271110.5OXT, OXTR
45inflammatory responseGO:00695410.5TLR2, S100A12, TNF, CRP, PTX3, IL6
46positive regulation of chemokine biosynthetic processGO:04508010.4TNF, IL1B
47positive regulation of uterine smooth muscle contractionGO:07047410.4OXTR, OXT
48positive regulation of sequence-specific DNA binding transcription factor activityGO:05109110.3IL1B, TNF, IL6
49negative regulation of interleukin-17 productionGO:03270010.3TLR2, TLR4
50sleepGO:03043110.1OXT, OXTR

Molecular functions related to Chorioamnionitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:00202010.3ELANE, IL1R1, TNF
2lipopolysaccharide receptor activityGO:00187510.1TLR2, TLR4

Products for genes affiliated with Chorioamnionitis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Chorioamnionitis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet