MCID: CHR005
MIFTS: 56

Chorioamnionitis malady

Summaries for Chorioamnionitis

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A placenta disease that is an inflammation of the fetal membranes (amnion and chorion) due to a bacterial infection.

MalaCards: Chorioamnionitis is related to funisitis and cerebral palsy. An important gene associated with Chorioamnionitis is MMP8 (matrix metallopeptidase 8 (neutrophil collagenase)), and among its related pathways are Monoamine Transport and TGF-Beta Pathway. The compounds tenidap and endotoxin have been mentioned in the context of this disorder. Affiliated tissues include placenta, uterus and lung, and related mouse phenotypes are tumorigenesis and skeleton.

Wikipedia:63 Chorioamnionitis is an inflammation of the fetal membranes (amnion and chorion) due to a bacterial... more...

Aliases & Classifications for Chorioamnionitis

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS
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Aliases & Descriptions:

chorioamnionitis 8 10 44 60


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Disease Ontology8 DOID:0050697

Related Diseases for Chorioamnionitis

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17GeneCards, 18GeneDecks
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Diseases related to Chorioamnionitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 237)
idRelated DiseaseScoreTop Affiliating Genes
1funisitis30.8MMP8
2cerebral palsy30.5MMP8
3pre-eclampsia30.2PTX3, IL6, OXT, FLT1, TLR4
4appendicitis30.1CRP
5hepatitis30.1TLR2
6hypertension29.8CRP
7influenza29.8LTF
8bacteriuria29.8CRP
9malaria29.8TNF, TLR2
10retinopathy of prematurity29.8FLT1
11otitis media29.8IL1B, LTF, TLR2
12crohn's disease29.8LTF, CRP, TNF
13bacterial vaginosis29.8IL1B, IL8, IL1R1, LTF
14respiratory failure29.8IL6, IL1B, CRP, TNF
15placental insufficiency29.8FLT1
16endometriosis29.8IL6, IL1B, IL8, IL1R1, OXTR, FLT1
17vasculitis29.8ELANE, PTX3, LTF, CRP, TNF, S100A12
18pneumonia29.8ELANE, MMP8, IL6, IL1B, IL8, CRP
19asthma29.8ELANE, MMP8, IL1B, IL8, FLT1, TNF
20cerebritis10.4
21vaginitis10.3
22cervicitis10.2
23endometritis10.2
24eclampsia10.1
25placental abruption10.1
26leukemoid reaction10.0
27aortic aneurysm10.0CRP
28osteomyelitis10.0CRP
29rhinitis10.0IL8
30amyloidosis10.0CRP
31irritable bowel syndrome10.0LTF
32leprosy10.0TLR2
33pleurisy10.0IL1B
34multiple myeloma10.0IL6
35rheumatic fever10.0CRP
36hypercholesterolemia10.0CRP
37ischemia10.0FLT1
38bronchiolitis obliterans10.0MMP8, IL8
39septic arthritis10.0CRP
40peptic ulcer10.0IL8
41gastric ulcer10.0TLR2
42acute pyelonephritis10.0CRP
43gingival overgrowth10.0IL1B
44kaposi's sarcoma10.0IL6
45bronchiolitis10.0IL8, TLR4
46herpes simplex10.0TLR2
47measles10.0TLR2
48diabetic retinopathy10.0FLT1
49myopathy10.0CRP
50prostatitis10.0LTF

Graphical network of the top 20 diseases related to Chorioamnionitis:



Diseases related to chorioamnionitis

Clinical Features for Chorioamnionitis

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Drugs & Therapeutics for Chorioamnionitis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Chorioamnionitis

Drug clinical trials:

Search ClinicalTrials for Chorioamnionitis

Search NIH Clinical Center for Chorioamnionitis

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Genetic Tests for Chorioamnionitis

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Anatomical Context for Chorioamnionitis

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32MalaCards
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MalaCards organs/tissues related to Chorioamnionitis:

32
Placenta, Uterus, Lung, Brain, Colon, Endothelial, Fetal lung, Monocytes, Thymus, Heart, Fetal brain, T cells, Bone marrow, Spleen, Bone, Skin, Testes

Animal Models for Chorioamnionitis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Chorioamnionitis:

36 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000200610.4TNF, IL1R1, IL1B, IL6, MMP8, ELANE
2MP:000539010.4IL6, IL1B
3MP:000536910.3TLR4, TLR2, FLT1, OXTR, RAMP2
4MP:001077110.3TLR4, TLR2, OXTR, OXT, IL1R1, IL6
5MP:000537610.1TLR4, TLR2, CRP, OXT, LTF, HPGD
6MP:000538910.1TLR4, FLT1, OXTR, OXT, IL1RN, RAMP2
7MP:000539710.1TLR4, TLR2, TNF, FLT1, LTF, IL1RN
8MP:000538510.0TLR4, TLR2, TNF, CRP, FLT1, OXT
9MP:000537910.0TLR2, TNF, OXTR, OXT, HPGD, IL1R1
10MP:000537010.0TLR4, TLR2, TNF, LTF, IL1R1, IL6
11MP:00036319.9RAMP2, OXT, OXTR, TLR4
12MP:00053879.9ELANE, TLR4, TLR2, TNF, CRP, FLT1
13MP:00107689.8TLR4, TLR2, TNF, FLT1, OXT, HPGD

Publications for Chorioamnionitis

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50PubMed
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Articles related to Chorioamnionitis:

(show top 50)    (show all 524)
idTitleAuthorsYear
1
Silent chorioamnionitis and associated pregnancy outcomes: a review of clinical data gathered over a 16-year period. (24421211)
2014
2
Predictive value of clinical chorioamnionitis in extremely premature infants. (23279059)
2013
3
Histological Chorioamnionitis and Neonatal Outcome in Preterm Infants. (24289975)
2013
4
The consequences of chorioamnionitis: preterm birth and effects on development. (23533760)
2013
5
Histological chorioamnionitis and bronchopulmonary dysplasia: a retrospective cohort study. (23238570)
2013
6
The association of histological chorioamnionitis and antenatal steroids on neonatal outcome in preterm infants born at less than thirty-four weeks' gestation. (22907714)
2012
7
Annexin A2 in amniotic fluid: correlation with histological chorioamnionitis, preterm premature rupture of membranes, and subsequent preterm delivery. (21955246)
2012
8
Congenital miliaria crystallina in a term neonate born to a mother with chorioamnionitis. (21995297)
2012
9
Histological chorioamnionitis - implication for bacterial colonization, laboratory markers of infection, and early onset sepsis in very-low-birth-weight neonates. (21609204)
2012
10
Discussion: 'Risk of repeat clinical chorioamnionitis,' by Cohen-Cline et al. (23092765)
2012
11
Neonatal and neurodevelopmental outcomes of very low birth weight infants with histologic chorioamnionitis. (20961565)
2011
12
Chorioamnionitis: from pathogenesis to treatment. (21672080)
2011
13
Neutrophil elastase and interleukin-6 in amniotic fluid as indicators of chorioamnionitis and funisitis. (21645958)
2011
14
Chorioamnionitis, respiratory distress syndrome and bronchopulmonary dysplasia in extremely low birth weight infants. (20724990)
2011
15
Placental features of chorioamnionitis colonized with Ureaplasma species in preterm delivery. (19858776)
2010
16
The relationship between leukemoid reaction and perinatal morbidity, mortality, and chorioamnionitis in low birth weight infants. (20851018)
2010
17
Chorioamnionitis and cerebral palsy: a meta-analysis. (21099620)
2010
18
Reduced mortality and increased BPD with histological chorioamnionitis and leukocytosis in very-low-birth-weight infants. (19710675)
2010
19
Chorioamnionitis and intrauterine fetal death after second-trimester amniocentesis. (19893298)
2009
20
Effect of chorioamnionitis on brain development and injury in premature newborns. (19743455)
2009
21
Chorioamnionitis, postnatal factors and proinflammatory response in the pathogenetic sequence of bronchopulmonary dysplasia. (19494557)
2009
22
Neonatal outcomes in the setting of preterm premature rupture of membranes complicated by chorioamnionitis. (19557664)
2009
23
The pathogenesis of chorioamnionitis. (18571522)
2008
24
Amniotic fluid heat shock protein 70 concentration in histologic chorioamnionitis, term and preterm parturition. (18570125)
2008
25
Subphrenic abscess after cesarean section in term pregnancy complicated by chorioamnionitis. (18570582)
2008
26
Pre-term pre-labour rupture of membranes: effect of chorioamnionitis on overall neonatal outcome. (17130019)
2006
27
The significance of C-reactive protein in the diagnosis of fetal tachycardia and therapy of chorioamnionitis. (16108395)
2005
28
Chorioamnionitis increases neonatal morbidity in pregnancies complicated by preterm premature rupture of membranes. (15846196)
2005
29
Chorioamnionitis/funisitis and the development of bronchopulmonary dysplasia. (15228562)
2004
30
Immunohistochemical distribution of Toll-like receptor 4 in term and preterm human placentas from normal and complicated pregnancy including chorioamnionitis. (14745724)
2004
31
Increased rates of chorioamnionitis with extra-amniotic saline infusion method of labor induction. (15051565)
2004
32
Relationship between histologic chorioamnionitis and early inflammatory variables in blood, tracheal aspirates, and endotracheal colonization in preterm infants. (12672904)
2003
33
Single additional dose postpartum therapy for women with chorioamnionitis. (14672470)
2003
34
Regulation of FasL/Fas in human trophoblasts: possible implications for chorioamnionitis. (12700199)
2003
35
Subclinical chorioamnionitis as a causal factor in unexplained stillbirths. (11502300)
2001
36
Chorioamnionitis, not epidural analgesia, is associated with maternal fever during labour. (11744590)
2001
37
Chorioamnionitis and early-onset neonatal sepsis do not significantly affect levels of interleukin-6 in very low birth weight neonates]. (12092128)
2001
38
Chorioamnionitis and uterine function. (10831982)
2000
39
Acute thymic involution in fetuses and neonates with chorioamnionitis. (11014581)
2000
40
Association between a shift in vaginal flora on Papanicolaou smear and acute chorioamnionitis and preterm delivery. (10405799)
1999
41
Randomized trial of single-dose versus multiple-dose cefotetan for the postpartum treatment of intrapartum chorioamnionitis. (9369828)
1997
42
Amniotic fluid granulocyte colony stimulating factor levels: a rapid marker for diagnosing chorioamnionitis. (9352016)
1997
43
International Multicentre Term Prelabor Rupture of Membranes Study: evaluation of predictors of clinical chorioamnionitis and postpartum fever in patients with prelabor rupture of membranes at term. (9396886)
1997
44
Emphysematous chorioamnionitis diagnosed by ultrasonography. (9259946)
1997
45
Fusobacterium chorioamnionitis: report of two cases in preterm labor with intact amniotic membranes. (18476100)
1996
46
Chorioamnionitis due to pseudomonas aeruginosa: a complication of prolonged antibiotic therapy for premature rupture of membranes. (8616140)
1996
47
Chorioamnionitis due to Pseudomonas aeruginosa: a complication of prolonged antibiotic therapy for premature rupture of membranes. (8863720)
1996
48
Association of post-cesarean delivery endometritis with colonization of the chorioamnion by Ureaplasma urealyticum. (7898825)
1995
49
Chorioamnionitis and serum IgM in Wilson-Mikity syndrome. (2589873)
1989
50
Placental abruption in the preterm gestation: an association with chorioamnionitis. (2733948)
1989

Genetic Variations for Chorioamnionitis

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Expression for genes affiliated with Chorioamnionitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Chorioamnionitis

Search GEO for disease gene expression data for Chorioamnionitis.

Pathways for genes affiliated with Chorioamnionitis

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37NCBI BioSystems Database, 51QIAGEN, 52R&D Systems, 29KEGG, 12EMD Millipore, 53Reactome, 59Tocris Bioscience, 4Cell Signaling Technology
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Pathways related to Chorioamnionitis according to GeneCards/GeneDecks:

(show top 50)    (show all 53)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.4IL1R1
2
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10.4FLT1
3
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10.4IL6, IL1R1
4
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10.4TLR2, TLR4
510.4TLR2, TLR4
610.4TLR4, TLR2
7
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10.4IL1R1, FLT1
8
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10.4FLT1, TLR4
9
Cytokine production by Th17 cells in CF (Mouse model)
10.3TLR4, IL8, IL6
1010.3IL8, TNF, IL6
1110.3MMP8, ELANE, LTF
1210.3TNF, IL6, ELANE
1310.3IL1B, TNF, IL6
1410.3TNF, IL1B, IL6
15
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10.3IL1R1, IL1B, IL1RN
1610.3IL1R1, TLR4, TNF
1710.3TLR4, IL6, IL1B, IL8
1810.3IL6, TLR4, TLR2, IL8
1910.3IL1B, IL6, TLR2, IL8
20
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10.3TNF, IL1B, IL6, IL8
2110.3IL6, IL1B, IL8, TNF
2210.3CRP, IL6, TNF, IL1B
23
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10.3IL1R1, IL1RN, IL1B, IL6
2410.3IL1B, IL6, IL1R1, TNF
2510.3TNF, TLR4, IL6, IL1B
26
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10.3TLR4, IL1R1, IL1B, TLR2
2710.3IL6, TLR4, TLR2, TNF
28
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10.3TLR4, TNF, IL1R1, IL1B
2910.2TLR4, IL1B, TNF, TLR2
3010.2TLR4, TLR2, IL1B, TNF
3110.2ELANE, IL8, IL6, HPGD, FLT1
3210.2TNF, IL1B, IL8, TLR4, IL6
3310.2IL1R1, IL1B, TLR4, TNF, IL8
3410.2IL6, IL1B, IL8, IL1RN, TNF
3510.2IL6, IL1B, TNF, TLR4, IL1R1
36
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10.2IL6, IL1B, TNF, TLR2, TLR4
3710.2TLR4, TLR2, IL6, TNF, IL1B
38
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10.2IL1R1, TNF, TLR2, IL1B, TLR4
39
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10.2TLR4, TLR2, IL1R1, IL1B, TNF
40
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10.2IL1B, OXT, IL6, RAMP2, OXTR
41
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10.2IL8, IL6, IL1B, TNF, TLR4, IL1R1
42
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10.2TLR2, TNF, IL8, IL1B, IL6, TLR4
43
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10.2TLR4, IL6, TLR2, TNF, IL8, IL1B
4410.2IL6, IL8, TLR2, IL1B, TLR4, TNF
4510.1TLR4, TNF, IL1R1, IL8, IL1B, IL6
46
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10.1TNF, IL1R1, TLR2, IL8, IL1B, TLR4
47
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10.1IL1B, IL1R1, FLT1, TNF, TLR4, TLR2
48
Immune response Bacterial infections in normal airways
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10.0IL8, IL6, IL1B, IL1R1, IL1RN, TNF
49
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10.0IL6, IL1B, IL8, FLT1, IL1R1, TLR4
50
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10.0TLR4, IL6, IL1B, TLR2, S100A12, IL1R1

Compounds for genes affiliated with Chorioamnionitis

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44Novoseek, 28IUPHAR, 2BitterDB, 59Tocris Bioscience, 11DrugBank, 24HMDB, 49PharmGKB
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Compounds related to Chorioamnionitis according to GeneCards/GeneDecks:

(show top 50)    (show all 210)
idCompoundScoreTop Affiliating Genes
1tenidap44 2811.8LTF, IL1R1
2endotoxin4410.8LTF, HPGD
3gabexate mesilate4410.8ELANE
4cycloheximide4410.8TLR2
5hydrocortisone44 2 59 1113.7FLT1, LTF, IL8, ELANE
6pentoxifylline44 1111.7LTF, IL1RN, IL1R1, ELANE
7cyclosporin a44 28 5912.6LTF, IL1R1, MMP8, ELANE
8h2o24410.6MMP8, FLT1, LTF, IL1RN, IL1R1
9anakinra44 1111.6IL1RN, IL1R1, IL1B, CRP, IL6, TNF
10superoxide44 2411.6MMP8, IL1B, LTF, TNF, ELANE
11hbd24410.5IL8, TLR4, TLR2, DEFB103B, IL1B, IL6
12prostaglandin4410.5IL1B, IL1R1, TNF, OXTR, HPGD, IL1RN
13indomethacin44 59 28 1113.5HPGD, IL1R1, OXTR, LTF
14gold sodium thiomalate4410.5IL8, IL1R1, TNF, IL1RN, IL1B
15sulfasalazine44 28 49 1113.5IL1RN, IL1B, CRP, IL1R1, IL8, TNF
16etanercept44 49 1112.5IL6, IL1R1, IL1RN, CRP, IL8, TNF
17zymosan4410.5TLR2, TNF, TLR4, LTF, IL1RN, ELANE
18polyinosinic-polycytidylic acid4410.5TLR2, IL8, IL1B, IL6, TLR4, TNF
19infliximab44 49 1112.5IL6, IL1R1, IL1RN, CRP, IL1B, TLR4
20peptidoglycan44 2811.5IL1RN, IL1R1, IL8, IL1B, IL6, TNF
21lipoteichoic acid4410.5TLR4, TLR2, TNF, IL1RN, IL1R1, IL8
22il 104410.5IL1RN, TNF, TLR2, TLR4, IL1R1, IL8
23polymyxin b4410.5IL6, TLR2, TNF, LTF, IL1RN, TLR4
24poly(i-c)4410.5TLR4, TNF, IL1B, IL6, TLR2, IL8
25ivig4410.5S100A12, TNF, IL1RN, IL1R1, IL6, CRP
26adalimumab44 49 1112.5TNF, CRP, IL1RN, IL1R1, IL6
27ccl344 2811.5IL1R1, IL8, TNF, IL1B, IL6, PTX3
28rantes4410.4IL1R1, TLR2, IL1B, IL6, TNF, TLR4
29neopterin4410.4ELANE, IL6, IL1B, IL8, IL1R1, IL1RN
30il-124410.4IL8, IL6, IL1B, TNF, IL1R1
31leukotriene b444 59 2412.4ELANE, TLR2, LTF, HPGD, IL1RN, IL1R1
32fibrinogen4410.3IL1RN, IL6, IL1R1, MMP8, ELANE, LTF
33n acetylcysteine4410.3IL6, IL1R1, TLR4, TNF, CRP, IL1B
34sb 20358044 5911.3IL6, TLR2, IL1R1, IL8, TNF, IL1RN
35simvastatin44 49 59 28 11 2415.3IL6, TLR4, TLR2, TNF, CRP, IL1RN
36imiquimod44 28 59 1113.3TLR4, TLR2, IL6, IL8, TNF
37lactate4410.3TLR4, ELANE, MMP8, IL6, IL8, IL1R1
38dexamethasone44 49 28 1113.3PTX3, RAMP2, IL6, IL1R1, HPGD, OXTR
39fmlp4410.3IL1RN, ELANE, LTF
40actinomycin d4410.3IL1R1, PTX3, IL6, IL1B, IL8, LTF
41hyaluronic acid44 2411.3ELANE, IL1RN, IL1R1, IL8, IL1B, LTF
42leflunomide49 44 1112.2TNF, IL1R1, IL6, IL1RN, IL1B
43polysulfone4410.2IL1RN, ELANE, IL1R1, IL1B
44nitric oxide44 11 2412.2IL1R1, IL6, FLT1, IL8, OXT, IL1B
45vegf4410.1LTF, OXT, OXTR, FLT1, TNF, TLR2
46serine4410.1LTF, OXT, FLT1, TNF, IL8, TLR2
47histamine44 28 2412.1TLR4, TLR2, TNF, LTF, IL1RN, IL1B
48retinoic acid44 2411.1OXT, TLR4, TLR2, TNF, LTF, IL1RN
49cysteine4410.0DEFB103B, TLR2, TLR4, IL8, IL1R1, OXT
50alanine449.7LTF, HPGD, IL1RN, IL1R1, IL6, OXTR

GO Terms for genes affiliated with Chorioamnionitis

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16Gene Ontology
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Cellular components related to Chorioamnionitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1secretory granuleGO:03014110.3ELANE, IL1B, LTF, OXT
2cell surfaceGO:00998610.2TLR2, TNF, RAMP2, ELANE, IL1R1
3extracellular spaceGO:00561510.1TNF, CRP, FLT1, OXT, IL1RN, IL8
4integral to plasma membraneGO:00588710.0FLT1, RAMP2, IL1R1, OXTR, TNF, TLR2
5external side of plasma membraneGO:00989710.0TLR4, IL6, TLR2, TNF
6extracellular regionGO:0055769.9ELANE, S100A12, TNF, CRP, OXT, LTF
7plasma membraneGO:0058869.9RAMP2, IL1R1, IL1RN, OXTR, TLR4, FLT1

Biological processes related to Chorioamnionitis according to GeneCards/GeneDecks:

(show top 50)    (show all 57)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of chemokine biosynthetic processGO:04507910.8ELANE, IL6
2positive regulation of norepinephrine secretionGO:01070110.8OXT, OXTR
3negative regulation of lipid storageGO:01088810.8TNF, IL6, CRP
4chronic inflammatory response to antigenic stimulusGO:00243910.7IL1RN, TNF
5positive regulation of calcidiol 1-monooxygenase activityGO:06055910.7IL1B, TNF
6sequestering of triglycerideGO:03073010.7IL1B, TNF
7positive regulation of interleukin-8 biosynthetic processGO:04541610.7TLR4, ELANE, TNF
8positive regulation of interleukin-8 productionGO:03275710.7TLR4, IL1B, TLR2
9negative regulation of growth of symbiont in hostGO:04413010.7TLR2, TNF, ELANE
10monocyte chemotaxisGO:00254810.7S100A12, FLT1, IL6
11positive regulation of penile erectionGO:06040610.7OXT, OXTR
12positive regulation of chemokine productionGO:03272210.7TLR4, TLR2, IL6, TNF
13acute-phase responseGO:00695310.7IL6, CRP, IL1RN
14defense response to Gram-positive bacteriumGO:05083010.7TNF, CRP, IL6, TLR2
15positive regulation of interferon-gamma productionGO:03272910.7IL1B, TNF, TLR4
16positive regulation of heterotypic cell-cell adhesionGO:03411610.7IL1B, TNF
17response to progesterone stimulusGO:03257010.7RAMP2, OXTR, OXT
18positive regulation of NF-kappaB import into nucleusGO:04234610.7TLR4, TNF, TLR2, IL1B
19response to yeastGO:00187810.7PTX3, ELANE
20negative regulation of gastric acid secretionGO:06045510.7OXT, OXTR
21lipopolysaccharide-mediated signaling pathwayGO:03166310.7TNF, IL1B, TLR4, TLR2
22neutrophil chemotaxisGO:03059310.7IL1B, IL8, S100A12
23positive regulation of smooth muscle cell proliferationGO:04866110.7ELANE, IL6, TNF
24humoral immune responseGO:00695910.7IL6, TNF, LTF
25response to glucocorticoid stimulusGO:05138410.7IL1RN, OXT, IL6, TNF
26positive regulation of MAP kinase activityGO:04340610.6TNF, S100A12, ELANE, FLT1
27positive regulation of interleukin-6 productionGO:03275510.6IL6, TLR4, TLR2, TNF, IL1B
28positive regulation of fever generationGO:03162210.6TNF, IL1B
29sperm ejaculationGO:04271310.6OXTR, OXT
30female pregnancyGO:00756510.6IL1RN, OXTR, RAMP2, HPGD, OXT
31memoryGO:00761310.6IL1RN, OXT, OXTR
32positive regulation of prostaglandin secretionGO:03230810.6OXT, IL1B
33positive regulation of macrophage cytokine productionGO:06090710.6TLR4, TLR2
34positive regulation of I-kappaB kinase/NF-kappaB cascadeGO:04312310.6LTF, IL1B, S100A12, TNF, TLR4
35positive regulation of inflammatory responseGO:05072910.6TLR4, TLR2, S100A12
36positive regulation of JNK cascadeGO:04633010.6TLR4, IL1B, TNF
37positive regulation of nitric oxide biosynthetic processGO:04542910.6TLR2, TLR4, TNF, IL1B, IL6, PTX3
38immune responseGO:00695510.6IL8, IL1B, IL1R1, IL1RN, TLR2, TLR4
39cellular response to lipoteichoic acidGO:07122310.6TLR2, TLR4
40epithelial cell proliferation involved in salivary gland morphogenesisGO:06066410.5TNF, IL6
41positive regulation of NF-kappaB transcription factor activityGO:05109210.5TLR2, TNF, IL6, S100A12, TLR4, LTF
42response to estradiol stimulusGO:03235510.5OXTR, RAMP2, OXT
43opsonizationGO:00822810.5PTX3, CRP
44maternal behaviorGO:04271110.5OXT, OXTR
45inflammatory responseGO:00695410.5TLR2, S100A12, TNF, CRP, PTX3, IL6
46positive regulation of chemokine biosynthetic processGO:04508010.4TNF, IL1B
47positive regulation of uterine smooth muscle contractionGO:07047410.4OXTR, OXT
48positive regulation of sequence-specific DNA binding transcription factor activityGO:05109110.3IL1B, TNF, IL6
49negative regulation of interleukin-17 productionGO:03270010.3TLR2, TLR4
50sleepGO:03043110.1OXT, OXTR

Molecular functions related to Chorioamnionitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:00202010.3ELANE, IL1R1, TNF
2lipopolysaccharide receptor activityGO:00187510.1TLR2, TLR4

Products for genes affiliated with Chorioamnionitis

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  • Antibodies
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Sources for Chorioamnionitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet