MCID: CHR074
MIFTS: 49

Choriocarcinoma

Categories: Rare diseases, Cancer diseases, Fetal diseases

Aliases & Classifications for Choriocarcinoma

MalaCards integrated aliases for Choriocarcinoma:

Name: Choriocarcinoma 12 72 49 36 51 41 14 69
Chorioepithelioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3594
ICD10 32 C58
MeSH 41 D002822
NCIt 46 C2948
KEGG 36 H00028
UMLS 69 C0008497

Summaries for Choriocarcinoma

MalaCards based summary : Choriocarcinoma, also known as chorioepithelioma, is related to gestational choriocarcinoma and choriocarcinoma of ovary. An important gene associated with Choriocarcinoma is HOPX (HOP Homeobox), and among its related pathways/superpathways are Glucose / Energy Metabolism and Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors. The drugs Chorionic Gonadotropin and Bleomycin have been mentioned in the context of this disorder. Affiliated tissues include placenta, ovary and lung, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 72 Choriocarcinoma is a malignant, trophoblasticcancer, usually of the placenta. It is characterized by... more...

Related Diseases for Choriocarcinoma

Diseases related to Choriocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 178)
# Related Disease Score Top Affiliating Genes
1 gestational choriocarcinoma 33.8 ABCG2 CSH1
2 choriocarcinoma of ovary 33.5 CSH1 CSH2
3 choriocarcinoma of the testis 33.4 CSH1 CSH2 HLA-G
4 non-gestational choriocarcinoma 33.3 CSH1 CSH2
5 hydatidiform mole, recurrent, 1 32.7 CGA CGB3 CGB5
6 mixed germ cell tumor 30.9 CGA CGB3
7 ectopic pregnancy 30.9 CGA CGB3 CGB5
8 epithelioid trophoblastic tumor 30.6 CGB3 CSH1
9 nonseminomatous germ cell tumor 30.4 CGB5 CGB7
10 testicular cancer 30.3 CGA CGB3 CGB5
11 testicular seminoma 30.1 CGA CGB3
12 malignant germ cell tumor 30.0 ALPPL2 CGA CGB5
13 placental site trophoblastic tumor 29.7 CGB3 CGB5 CSH1 GPC3 LNPEP
14 seminoma 29.6 ALPPL2 CGA CGB3 CGB5 CGB7
15 placental choriocarcinoma 12.1
16 fallopian tube gestational choriocarcinoma 12.0
17 pineal region choriocarcinoma 12.0
18 non-gestational ovarian choriocarcinoma 12.0
19 gestational ovarian choriocarcinoma 12.0
20 primary non-gestational choriocarcinoma of ovary 12.0
21 childhood choriocarcinoma of the testis 11.9
22 adult central nervous system choriocarcinoma 11.9
23 pediatric cns choriocarcinoma 11.9
24 pulmonary artery choriocarcinoma 11.8
25 testicular monophasic choriocarcinoma 11.8
26 gestational uterine corpus choriocarcinoma 11.8
27 uterine corpus choriocarcinoma 11.8
28 childhood choriocarcinoma of the ovary 11.8
29 choriocarcinoma of the central nervous system 11.8
30 gestational trophoblastic tumor 11.5
31 testicular germ cell tumor 11.3
32 teratocarcinoma 10.9
33 anorchia 10.5 CGA CGB5
34 sacrococcygeal teratoma 10.5 CGA CGB7
35 triploidy 10.5 CGA CGB7
36 oocyte maturation defect 1 10.5 CGA CYP19A1
37 aromatase excess syndrome 10.5 CGB5 CYP19A1
38 complete androgen insensitivity syndrome 10.4 ALPPL2 CGA CYP19A1
39 luteoma 10.4 CGA CYP19A1
40 chromosomal triplication 10.4 CGA CGB3
41 testicular trophoblastic tumor 10.4 CSH1 CSH2
42 cryptorchidism, unilateral or bilateral 10.3 ALPPL2 CGA CGB5 CYP19A1
43 trophoblastic neoplasm 10.3 CGA CSH1 LNPEP
44 invasive mole 10.3
45 testicular granulosa cell tumor 10.3 CSH1 CSH2
46 ovarian disease 10.3 CGA CYP11A1 CYP19A1
47 juvenile type testicular granulosa cell tumor 10.3 CSH1 CSH2
48 uterine anomalies 10.2 CSH1 CSH2 CYP19A1
49 testicular leydig cell tumor 10.2 CGB3 CYP11A1
50 placenta disease 10.2 CGB3 CSH1 CSH2

Graphical network of the top 20 diseases related to Choriocarcinoma:



Diseases related to Choriocarcinoma

Symptoms & Phenotypes for Choriocarcinoma

GenomeRNAi Phenotypes related to Choriocarcinoma according to GeneCards Suite gene sharing:

25 (show all 11)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-103 9.58 HLA-G
2 Increased shRNA abundance (Z-score > 2) GR00366-A-110 9.58 HLA-G
3 Increased shRNA abundance (Z-score > 2) GR00366-A-118 9.58 CGB3 CGB5 CGB7 HLA-G
4 Increased shRNA abundance (Z-score > 2) GR00366-A-156 9.58 HLA-G
5 Increased shRNA abundance (Z-score > 2) GR00366-A-178 9.58 HLA-G
6 Increased shRNA abundance (Z-score > 2) GR00366-A-19 9.58 HLA-G
7 Increased shRNA abundance (Z-score > 2) GR00366-A-31 9.58 HLA-G
8 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.58 CGB3 CGB5 CGB7
9 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.58 CGB3 CGB5 CGB7
10 Increased shRNA abundance (Z-score > 2) GR00366-A-7 9.58 HLA-G
11 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.58 HLA-G

Drugs & Therapeutics for Choriocarcinoma

Drugs for Choriocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 152)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Chorionic Gonadotropin Phase 4
2
Bleomycin Approved, Investigational Phase 2, Phase 3 11056-06-7 5360373
3
Cisplatin Approved Phase 2, Phase 3, Phase 1 15663-27-1 2767 441203 84093
4
Etoposide Approved Phase 2, Phase 3, Phase 1 33419-42-0 36462
5
Lenograstim Approved, Investigational Phase 2, Phase 3, Phase 1 135968-09-1
6
Paclitaxel Approved, Vet_approved Phase 2, Phase 3, Phase 1 33069-62-4 36314
7
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
8
Mechlorethamine Approved, Investigational Phase 3,Phase 1,Phase 2 51-75-2 4033
9
Oxaliplatin Approved, Investigational Phase 3,Phase 1 61825-94-3 43805 6857599 5310940 9887054
10
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 50-02-2 5743
11
Mesna Approved, Investigational Phase 3,Phase 1,Phase 2 3375-50-6 598
12
Dactinomycin Approved, Investigational Phase 3 50-76-0 457193 2019
13
Methotrexate Approved Phase 3,Phase 2 1959-05-2, 59-05-2 126941
14
Captopril Approved Phase 3 62571-86-2 44093
15
Cyclophosphamide Approved, Investigational Phase 3,Phase 1 50-18-0, 6055-19-2 2907
16
Palivizumab Approved, Investigational Phase 3 188039-54-5
17
Ribavirin Approved Phase 3 36791-04-5 37542
18
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
19
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
20
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
21
Amphotericin B Approved, Investigational Phase 3 1397-89-3 5280965 14956
22
Caspofungin Approved Phase 3 162808-62-0, 179463-17-3 2826718 468682
23
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 38904 498142
24
Levoleucovorin Approved, Investigational Phase 3,Phase 2,Phase 1 68538-85-2
25
Diphenhydramine Approved, Investigational Phase 3 58-73-1, 147-24-0 3100
26
Promethazine Approved, Investigational Phase 3 60-87-7 4927
27
Vinblastine Approved Phase 3 865-21-4 241903 13342
28
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
29
leucovorin Approved, Nutraceutical Phase 3,Phase 2,Phase 1 58-05-9 143 6006
30 Albumin-Bound Paclitaxel Phase 2, Phase 3, Phase 1
31 Anti-Bacterial Agents Phase 2, Phase 3, Phase 1
32 Antibiotics, Antitubercular Phase 2, Phase 3
33 Antimitotic Agents Phase 2, Phase 3, Phase 1
34 Antineoplastic Agents, Phytogenic Phase 2, Phase 3, Phase 1
35 Etoposide phosphate Phase 2, Phase 3, Phase 1
36 Topoisomerase Inhibitors Phase 2, Phase 3, Phase 1
37 Alkylating Agents Phase 3,Phase 1,Phase 2
38 Isophosphamide mustard Phase 3,Phase 1,Phase 2 0
39 Anti-Infective Agents Phase 3,Phase 1,Phase 2
40 Antimetabolites Phase 3,Phase 2,Phase 1
41 Antimetabolites, Antineoplastic Phase 3,Phase 2,Phase 1
42 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
43 Antiviral Agents Phase 3,Phase 1,Phase 2
44 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
45 BB 1101 Phase 3,Phase 1,Phase 2
46 Dexamethasone acetate Phase 3,Phase 1,Phase 2 1177-87-3
47 Antirheumatic Agents Phase 3,Phase 2,Phase 1
48 Dermatologic Agents Phase 3,Phase 2
49 Folic Acid Antagonists Phase 3,Phase 2
50 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 68)

# Name Status NCT ID Phase Drugs
1 Conformation of Beta Human Chorionic Gonadotropin During Chemotherapy for Choriocarcinoma Unknown status NCT00294177 Phase 4
2 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
3 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
4 Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia Completed NCT00003702 Phase 3 Methotrexate
5 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Completed NCT00053352 Phase 3 cisplatin;etoposide
6 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
7 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
8 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
9 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
10 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
11 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3 cisplatin;etoposide;ifosfamide
12 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide
13 Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain Completed NCT00293358 Phase 3 carboplatin;cisplatin;etoposide phosphate;ifosfamide
14 Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3 Bleomycin;Carboplatin;Cisplatin;Etoposide
15 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3 paclitaxel;ifosfamide;cisplatin;pegylated G-CSF;G-CSF;carboplatin;etoposide phosphate
16 Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia Active, not recruiting NCT01535053 Phase 3 Leucovorin Calcium;Methotrexate
17 Rescue Regimen and High Dose Methotrexate in Management of Presistent Gestational Trophoplastic Neoplasia Not yet recruiting NCT03280979 Phase 2, Phase 3 rescue regimen;high dose methotrxate
18 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
19 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2 cisplatin;gemcitabine hydrochloride;ifosfamide;paclitaxel
20 Single Patient Treatment Protocol of TRC105 Combined With Standard-dose Bevacizumab for a Single Patient With Metastatic And Refractory Choriocarcinoma Completed NCT02396511 Phase 2
21 A Trial for Patients With Gestational Trophoblastic Disease Completed NCT00190918 Phase 2 Pemetrexed
22 Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors Completed NCT00467051 Phase 2 paclitaxel;carboplatin;ifosfamide
23 Second Curettage in Treating Patients With Persistent Non-metastatic Gestational Trophoblastic Tumors Completed NCT00521118 Phase 2
24 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2 sunitinib malate
25 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
26 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2 cisplatin;etoposide
27 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
28 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
29 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
30 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
31 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
32 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2 carboplatin;cisplatin;etoposide phosphate;vincristine sulfate
33 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
34 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2 ixabepilone
35 Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Metastatic Testicular Cancer Completed NCT00004077 Phase 2 cisplatin;ifosfamide;paclitaxel
36 Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors Completed NCT00047320 Phase 2 carboplatin;etoposide;ifosfamide;thiotepa
37 Cisplatin and Etoposide Prior to Radiation Therapy in Treating Patients With CNS Tumors Completed NCT00002472 Phase 2 cisplatin;etoposide
38 Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors Completed NCT00005955 Phase 2 temozolomide
39 Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN) Recruiting NCT02664961 Phase 2 TRC105;Bevacizumab
40 Role of Axumin PET Scan in Germ Cell Tumor Recruiting NCT03426865 Phase 2 Axumin PET scan
41 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
42 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel;thiotepa;Mesna
43 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
44 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1 ipilimumab;therapeutic allogeneic lymphocytes
45 Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors Completed NCT00281944 Phase 1 oxaliplatin;fluorouracil;leucovorin calcium
46 Sunitinib in Treating Young Patients With Refractory Solid Tumors Completed NCT00387920 Phase 1 sunitinib malate
47 Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00929903 Phase 1 pazopanib hydrochloride
48 Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
49 Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma Completed NCT00994500 Phase 1 vorinostat;bortezomib
50 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1

Search NIH Clinical Center for Choriocarcinoma

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: choriocarcinoma

Genetic Tests for Choriocarcinoma

Anatomical Context for Choriocarcinoma

MalaCards organs/tissues related to Choriocarcinoma:

38
Placenta, Ovary, Lung, Testis, Brain, Bone, Bone Marrow

Publications for Choriocarcinoma

Articles related to Choriocarcinoma:

(show top 50) (show all 1125)
# Title Authors Year
1
Curcumol Controls Choriocarcinoma Stem-Like Cells Self-Renewal via Repression of DNA Methyltransferase (DNMT)- and Histone Deacetylase (HDAC)-Mediated Epigenetic Regulation. ( 29363667 )
2018
2
Disruption of thyroid hormone sulfotransferase activity by brominated flame retardant chemicals in the human choriocarcinoma placenta cell line, BeWo. ( 29331935 )
2018
3
Nonmetastatic Excised Gestational Choriocarcinoma: To Treat or Not to Treat. ( 29406249 )
2018
4
Debulking Surgery for Pelvic Recurrence After Surgically-treated Tubal Gestational Choriocarcinoma - A Case Report and Literature Review. ( 29277804 )
2018
5
Cancer-Specific Inhibitory Effects of Genetically Engineered Stem Cells Expressing Cytosine Deaminase and Interferon-I^ Against Choriocarcinoma in Xenografted Metastatic Mouse Models. ( 29202279 )
2018
6
Is chemotherapy always necessary for patients with nonmetastatic gestational trophoblastic neoplasia with histopathological diagnosis of choriocarcinoma? ( 29248195 )
2018
7
The role of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) in modulating immune detection of choriocarcinoma. ( 29324974 )
2018
8
Recurrent Cerebral Hemorrhage in Normal Pregnancy Secondary to Mycotic Pseudoaneurysms Related to Choriocarcinoma. ( 28987845 )
2018
9
Daidzein induces choriocarcinoma cell apoptosis in a dose-dependent manner via the mitochondrial apoptotic pathway. ( 29436666 )
2018
10
Targeted delivery of doxorubicin by CSA-binding nanoparticles for choriocarcinoma treatment. ( 29426237 )
2018
11
Relative Effects of Age, Race, and Stage on Mortality in Gestational Choriocarcinoma. ( 29232272 )
2018
12
Co-culture of H295R Adrenocortical Carcinoma and BeWo Choriocarcinoma Cells to Study Feto-placental Interactions: Focus on Estrogen Biosynthesis. ( 29197012 )
2018
13
The choriocarcinoma cell line JEG-3 upregulates regulatory T cell phenotypes and modulates pro-inflammatory cytokines through HLA-G. ( 29198970 )
2018
14
Durable remission for a woman with refractory choriocarcinoma treated with anti-endoglin monoclonal antibody and bevacizumab: A case from the New England Trophoblastic Disease Center, Brigham and Women's Hospital and Dana-Farber Cancer Institute. ( 29217138 )
2018
15
Silibinin stimluates apoptosis by inducing generation of ROS and ER stress in human choriocarcinoma cells. ( 28657208 )
2017
16
Primary non-gestational choriocarcinoma of the uterine cervix with metaplastic transformation from adenocarcinoma: a case report. ( 28830246 )
2017
17
Antagonism of EG-VEGF receptors as targeted therapy for choriocarcinoma progression in vitro and in vivo. ( 28899975 )
2017
18
Primary intestinal choriocarcinoma in a patient with long-standing Crohn's disease. ( 29205146 )
2017
19
Activation of Peroxisome Proliferator-Activated Receptor Gamma and Disruption of Progesterone Synthesis of 2-Ethylhexyl Diphenyl Phosphate in Human Placental Choriocarcinoma Cells: Comparison with Triphenyl Phosphate. ( 28282128 )
2017
20
Prognosis of gestational choriocarcinoma diagnosed incidentally during laparoscopy for a presumed cornual pregnancy: a report of five cases. ( 28607811 )
2017
21
Hypermethylation and loss of retinoic acid receptor responder 1 expression in human choriocarcinoma. ( 29169400 )
2017
22
Myricetin suppresses invasion and promotes cell death in human placental choriocarcinoma cells through induction of oxidative stress. ( 28428076 )
2017
23
An extremely rare case of postpartum gestational choriocarcinoma with long-term survival. ( 28777426 )
2017
24
Fatty acid-binding protein3 expression in BeWo cells, a human placental choriocarcinoma cell line. ( 28515017 )
2017
25
Role of chemotherapy and thrombolysis in treatment of choriocarcinoma accompanied with pulmonary embolism: A case report with literature review. ( 28885339 )
2017
26
A gestational choriocarcinoma of the ovary diagnosed by DNA polymorphic analysis: a case report and systematic review of the literature. ( 28728581 )
2017
27
Acquired Pulmonary Arteriovenous Fistula within Metastasis from Choriocarcinoma: A Case Report. ( 28878648 )
2017
28
Gestational choriocarcinoma complicated by infective endocarditis during chemotherapy. ( 28217736 )
2017
29
Gestational choriocarcinoma associated with a germline TP53 mutation. ( 28477316 )
2017
30
Postmenopausal choriocarcinoma: a rare case report and review of the literature. ( 28816932 )
2017
31
c-Rel Promotes Invasion of Choriocarcinoma Cells via PI3K/AKT Signaling. ( 28259870 )
2017
32
A Rare Case of Gestational Choriocarcinoma Presenting as Cornual Ectopic Pregnancy. ( 29032067 )
2017
33
Treatment of Human Placental Choriocarcinoma Cells with Formaldehyde and Benzene Induced Growth and Epithelial Mesenchymal Transition via Induction of an Antioxidant Effect. ( 28758930 )
2017
34
Hypoxia-induced and HIF1I+-VEGF-mediated tight junction dysfunction in choriocarcinoma cells: Implications for preeclampsia. ( 29223764 )
2017
35
Erratum: High-dose chemotherapy with autologous peripheral blood stem cell transplantation for choriocarcinoma: A case report and literature review. ( 28781822 )
2017
36
Complete Serologic Response to Pembrolizumab in a Woman With Chemoresistant Metastatic Choriocarcinoma. ( 28742453 )
2017
37
The STAT3/NFIL3 signaling axis-mediated chemotherapy resistance is reversed by Raddeanin A via inducing apoptosis in choriocarcinoma cells. ( 29215740 )
2017
38
Successful detection of SRY gene via fine needle biopsy: A case of extragenital gestational choriocarcinoma in the kidney. ( 29285373 )
2017
39
Metastatic gestational choriocarcinoma: a masquerader in obstetrics. ( 28550508 )
2017
40
Daidzein inhibits choriocarcinoma proliferation by arresting cell cycle at G1 phase through suppressing ERK pathway in vitro and in vivo. ( 28849226 )
2017
41
Coumestrol induces mitochondrial dysfunction by stimulating ROS production and calcium ion influx into mitochondria in human placental choriocarcinoma cells. ( 29040664 )
2017
42
miR-21 Is Overexpressed in Hydatidiform Mole Tissues and Promotes Proliferation, Migration, and Invasion in Choriocarcinoma Cells. ( 27922982 )
2017
43
Case Report: Multiple hemorrhagic metastases to the brain from primary lung choriocarcinoma. ( 28794859 )
2017
44
Evaluation of the effects of antiepileptic drugs on folic acid uptake by human placental choriocarcinoma cells. ( 29223574 )
2017
45
Clinical and ultrasound features of non-gestational ovarian choriocarcinoma. ( 29080278 )
2017
46
Primary Gastric Choriocarcinoma Presenting as a Pregnancy of Unknown Location. ( 28079767 )
2017
47
Collision tumor of choriocarcinoma and small cell carcinoma of the stomach: A case report. ( 28709051 )
2017
48
Chemotherapy during Pregnancy: Cases of Hodgkin's and Non-Hodgkin's Lymphoma, Chronic Myeloid Leukemia, Breast Cancer, Nasopharyngeal Cancer, and Choriocarcinoma. ( 28700986 )
2017
49
An unusual pulmonary metastatic manifestation of gestational choriocarcinoma: A diagnostic dilemma. ( 28869244 )
2017
50
Aberrantly Expressed SALL4 Promotes Cell Proliferation via I^-Catenin/c-Myc Pathway in Human Choriocarcinoma Cells. ( 28639477 )
2017

Variations for Choriocarcinoma

Expression for Choriocarcinoma

Search GEO for disease gene expression data for Choriocarcinoma.

Pathways for Choriocarcinoma

GO Terms for Choriocarcinoma

Cellular components related to Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.4 ALPPL2 CGA CGB3 CGB5 CGB7 CSH1
2 endosome lumen GO:0031904 9.26 CSH1 GH2
3 viral envelope GO:0019031 9.16 ERV3-1 ERVW-1
4 virion GO:0019012 8.96 ERV3-1 ERVW-1

Biological processes related to Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.65 CGA CGB3 CGB5 CGB7 LNPEP
2 sterol metabolic process GO:0016125 9.4 CYP11A1 CYP19A1
3 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 9.37 CSH1 GH2
4 peptide hormone processing GO:0016486 9.33 CGA CGB3 CGB5
5 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent GO:0002480 9.32 HLA-G LNPEP
6 regulation of receptor activity GO:0010469 9.17 CGA CGB3 CGB5 CGB7 CSH1 CSH2
7 female gamete generation GO:0007292 9.13 CGB3 CGB5 CGB7

Molecular functions related to Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.1 CGA CGB3 CGB7 CSH1 CSH2 GH2

Sources for Choriocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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