MCID: CHR074
MIFTS: 46

Choriocarcinoma malady

Categories: Rare diseases, Cancer diseases, Reproductive diseases, Fetal diseases

Aliases & Classifications for Choriocarcinoma

Aliases & Descriptions for Choriocarcinoma:

Name: Choriocarcinoma 12 50 52 42 14 69
Chorioepithelioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3594
ICD10 33 C58
MeSH 42 D002822
NCIt 47 C2948
UMLS 69 C0008497

Summaries for Choriocarcinoma

MalaCards based summary : Choriocarcinoma, also known as chorioepithelioma, is related to malignant teratoma and ovarian mucinous cystadenocarcinoma. An important gene associated with Choriocarcinoma is HOPX (HOP Homeobox), and among its related pathways/superpathways are Glucose / Energy Metabolism and Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors. The drugs Chorionic Gonadotropin and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include placenta, ovary and testis, and related phenotype is Increased shRNA abundance (Z-score > 2).

Wikipedia : 71 Choriocarcinoma is a malignant, trophoblasticcancer, usually of the placenta. It is characterized by... more...

Related Diseases for Choriocarcinoma

Diseases related to Choriocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 164)
id Related Disease Score Top Affiliating Genes
1 malignant teratoma 29.6 CSH1 CSH2 HLA-G
2 ovarian mucinous cystadenocarcinoma 26.7 ABCG2 CDKN1C CGA CGB3 CGB5 CGB7
3 gestational choriocarcinoma 12.3
4 placental choriocarcinoma 11.9
5 choriocarcinoma of the testis 11.9
6 non-gestational choriocarcinoma 11.9
7 choriocarcinoma of ovary 11.9
8 pineal region choriocarcinoma 11.9
9 non-gestational ovarian choriocarcinoma 11.9
10 gestational ovarian choriocarcinoma 11.8
11 fallopian tube gestational choriocarcinoma 11.8
12 childhood choriocarcinoma of the testis 11.7
13 adult central nervous system choriocarcinoma 11.7
14 pediatric cns choriocarcinoma 11.7
15 pulmonary artery choriocarcinoma 11.7
16 testicular monophasic choriocarcinoma 11.7
17 gestational uterine corpus choriocarcinoma 11.7
18 uterine corpus choriocarcinoma 11.7
19 childhood choriocarcinoma of the ovary 11.7
20 primary non-gestational choriocarcinoma of ovary 11.7
21 choriocarcinoma of the central nervous system 11.6
22 testicular germ cell tumor 11.2
23 teratocarcinoma 10.8
24 gestational trophoblastic neoplasm 10.8
25 agnosia 10.4 CSH1 CSH2
26 true unicornuate uterus 10.3 CGA CGB3
27 marfan syndrome 10.3 CGB5 CYP19A1
28 severe combined immunodeficiency 10.3 CGA CGB7
29 central nervous system endodermal sinus tumor 10.3 CSH1 CSH2
30 antisynthetase syndrome 10.3 CGA CGB5
31 blepharochalasis 10.3 CSH1 CSH2 CYP19A1
32 trypanosomiasis, human east-african 10.3 CGA CGB7
33 flying phobia 10.3 CSH1 CSH2
34 spondylolysis 10.3 CSH1 CSH2 CYP19A1
35 toxic encephalopathy 10.3 CDKN1C CSH1 CSH2
36 ovarian cystadenocarcinoma 10.2 CGB5 CSH1 LNPEP
37 toxascariasis 10.2 CDKN1C CSH1 CSH2
38 novak syndrome 10.2 CGB5 CGB7
39 gastric teratoma 10.2 CSH1 CSH2
40 anxiety disorder 10.2 ABCG2 SLC19A1 SLC6A4
41 breast myoepithelial neoplasm 10.2 CGA CGB3 CGB5
42 atopic dermatitis 10.2 CGA CGB3 CGB7
43 malignant teratocarcinosarcoma 10.2 CGA CGB5
44 welander distal myopathy 10.2 CGB5 HLA-G LNPEP
45 encephalomalacia 10.2 CDKN1C CSH1 SLC6A4
46 invasive mole 10.2
47 hereditary renal cell carcinoma 10.2 CGA CGB3 CGB7
48 parameningeal embryonal rhabdomyosarcoma 10.2 CGA CGB3 CGB5 CGB7
49 microcephaly, seizures, and developmental delay 10.2 CDKN1C CGA CGB3 CGB5
50 cervical spinal canal and spinal cord meningioma 10.1 CGA CYP19A1

Graphical network of the top 20 diseases related to Choriocarcinoma:



Diseases related to Choriocarcinoma

Symptoms & Phenotypes for Choriocarcinoma

GenomeRNAi Phenotypes related to Choriocarcinoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-103 9.58 HLA-G
2 Increased shRNA abundance (Z-score > 2) GR00366-A-110 9.58 HLA-G
3 Increased shRNA abundance (Z-score > 2) GR00366-A-118 9.58 HLA-G CGB3 CGB5 CGB7
4 Increased shRNA abundance (Z-score > 2) GR00366-A-156 9.58 HLA-G
5 Increased shRNA abundance (Z-score > 2) GR00366-A-178 9.58 HLA-G
6 Increased shRNA abundance (Z-score > 2) GR00366-A-19 9.58 HLA-G
7 Increased shRNA abundance (Z-score > 2) GR00366-A-31 9.58 HLA-G
8 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.58 CGB3 CGB5 CGB7
9 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.58 CGB3 CGB5 CGB7
10 Increased shRNA abundance (Z-score > 2) GR00366-A-7 9.58 HLA-G
11 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.58 HLA-G

Drugs & Therapeutics for Choriocarcinoma

Drugs for Choriocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 161)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Chorionic Gonadotropin Phase 4
2
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 50-02-2 5743
3
Paclitaxel Approved, Vet_approved Phase 2, Phase 3, Phase 1 33069-62-4 36314
4
Etoposide Approved Phase 2, Phase 3, Phase 1 33419-42-0 36462
5
Cisplatin Approved Phase 2, Phase 3, Phase 1 15663-27-1 84093 441203 2767
6
Bleomycin Approved Phase 2, Phase 3 11056-06-7 5360373
7
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
8
Mechlorethamine Approved Phase 3,Phase 1,Phase 2 51-75-2 4033
9
Oxaliplatin Approved, Investigational Phase 3,Phase 1 61825-94-3 5310940 9887054 6857599, 9887054 43805
10
Mesna Approved Phase 3,Phase 1,Phase 2 3375-50-6 598
11
Lenograstim Approved Phase 2, Phase 3, Phase 1 135968-09-1
12
Methotrexate Approved Phase 3 1959-05-2, 59-05-2 126941
13
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
14
Cyclophosphamide Approved, Investigational Phase 3,Phase 1 50-18-0, 6055-19-2 2907
15
Captopril Approved Phase 3 62571-86-2 44093
16
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
17
Ribavirin Approved Phase 3 36791-04-5 37542
18
Fluconazole Approved Phase 3 86386-73-4 3365
19
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
20
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
21
Dactinomycin Approved Phase 3 50-76-0 2019 457193
22
Palivizumab Approved, Investigational Phase 3 188039-54-5
23
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 468682 2826718
24
Levoleucovorin Approved Phase 3,Phase 1 68538-85-2
25
Succinylcholine Approved Phase 3 306-40-1 5314
26
Diphenhydramine Approved Phase 3 58-73-1, 147-24-0 3100
27
Promethazine Approved Phase 3 60-87-7 4927
28
Vinblastine Approved Phase 3 865-21-4 13342 241903
29
leucovorin Approved, Nutraceutical Phase 3,Phase 2,Phase 1 58-05-9 54575, 6560146 143
30
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
31 Dexamethasone acetate Phase 3,Phase 1,Phase 2 1177-87-3
32 Alkylating Agents Phase 3,Phase 1,Phase 2
33 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
34 Albumin-Bound Paclitaxel Phase 2, Phase 3, Phase 1
35 Topoisomerase Inhibitors Phase 2, Phase 3, Phase 1
36 Dexamethasone 21-phosphate Phase 3,Phase 1,Phase 2
37 Anti-Bacterial Agents Phase 2, Phase 3, Phase 1
38 Etoposide phosphate Phase 2, Phase 3, Phase 1
39 Anti-Infective Agents Phase 3,Phase 1,Phase 2
40 Immunosuppressive Agents Phase 3,Phase 1,Phase 2
41 Isophosphamide mustard Phase 3,Phase 1,Phase 2
42 Antimetabolites Phase 3,Phase 1,Phase 2
43 Antibiotics, Antitubercular Phase 2, Phase 3
44 Antimetabolites, Antineoplastic Phase 3,Phase 1,Phase 2
45 Antimitotic Agents Phase 2, Phase 3, Phase 1
46 Antineoplastic Agents, Alkylating Phase 3,Phase 1,Phase 2
47 BB 1101 Phase 3,Phase 1,Phase 2
48 Antineoplastic Agents, Phytogenic Phase 2, Phase 3, Phase 1
49 Antiviral Agents Phase 3,Phase 1,Phase 2
50 Hydroxyitraconazole Phase 3

Interventional clinical trials:

(show top 50) (show all 66)
id Name Status NCT ID Phase
1 Conformation of Beta Human Chorionic Gonadotropin During Chemotherapy for Choriocarcinoma Unknown status NCT00294177 Phase 4
2 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3
3 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3
4 Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia Completed NCT00003702 Phase 3
5 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3
6 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3
7 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3
8 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3
9 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3
10 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3
11 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3
12 Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain Completed NCT00293358 Phase 3
13 Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3
14 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3
15 Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia Active, not recruiting NCT01535053 Phase 3
16 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Active, not recruiting NCT00053352 Phase 3
17 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3
18 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2
19 A Trial for Patients With Gestational Trophoblastic Disease Completed NCT00190918 Phase 2
20 Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors Completed NCT00467051 Phase 2
21 Second Curettage in Treating Patients With Persistent Non-metastatic Gestational Trophoblastic Tumors Completed NCT00521118 Phase 2
22 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2
23 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2
24 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2
25 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
26 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
27 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
28 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
29 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2
30 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2
31 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2
32 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2
33 Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Metastatic Testicular Cancer Completed NCT00004077 Phase 2
34 Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors Completed NCT00047320 Phase 2
35 Cisplatin and Etoposide Prior to Radiation Therapy in Treating Patients With CNS Tumors Completed NCT00002472 Phase 2
36 Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors Completed NCT00005955 Phase 2
37 Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN) Recruiting NCT02664961 Phase 2
38 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
39 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2
40 Single Patient Treatment Protocol of TRC105 Combined With Standard-dose Bevacizumab for a Single Patient With Metastatic And Refractory Choriocarcinoma Active, not recruiting NCT02396511 Phase 2
41 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2
42 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1
43 Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors Completed NCT00281944 Phase 1
44 Sunitinib in Treating Young Patients With Refractory Solid Tumors Completed NCT00387920 Phase 1
45 Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00929903 Phase 1
46 Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors Completed NCT01076530 Phase 1
47 Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma Completed NCT00994500 Phase 1
48 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
49 Safety and Tolerability Study of AZD2171 in Combination With AZD0530 in Patients With Advanced Solid Tumours Completed NCT00475956 Phase 1
50 Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors Completed NCT00313599 Phase 1

Search NIH Clinical Center for Choriocarcinoma

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: choriocarcinoma

Genetic Tests for Choriocarcinoma

Anatomical Context for Choriocarcinoma

MalaCards organs/tissues related to Choriocarcinoma:

39
Placenta, Ovary, Testis, Lung, Brain, Liver, Breast

Publications for Choriocarcinoma

Articles related to Choriocarcinoma:

(show top 50) (show all 1071)
id Title Authors Year
1
Primary Gastric Choriocarcinoma Presenting as a Pregnancy of Unknown Location. ( 28079767 )
2017
2
miR-21 Is Overexpressed in Hydatidiform Mole Tissues and Promotes Proliferation, Migration, and Invasion in Choriocarcinoma Cells. ( 27922982 )
2017
3
SALL4 expression in gestational trophoblastic tumors: a useful tool to distinguish choriocarcinoma from placental site trophoblastic tumor and epithelioid trophoblastic tumor. ( 27068524 )
2016
4
Human Hemochromatosis Protein (HFE) Immunoperoxidase Stain Highlights Choriocarcinoma within Mixed Germ Cell Tumors. ( 27034532 )
2016
5
Recovery from Choriocarcinoma Syndrome Associated with a Metastatic Extragonadal Germ Cell Tumor Hemorrhage. ( 27403124 )
2016
6
Impact of Axis of GHRH and GHRH Receptor on Cell Viability and Apoptosis of the Placental Choriocarcinoma Cell Line. ( 26917260 )
2016
7
Over-expression of stomatin causes syncytium formation in nonfusogenic JEG-3 choriocarcinoma placental cells. ( 27306251 )
2016
8
Gestational choriocarcinoma: Rare spinal metastasis during a viable pregnancy. ( 27987335 )
2016
9
Corrigendum to "Long-chain polyunsaturated fatty acids stimulate cellular fatty acid uptake in human placental choriocarcinoma (Bewo) cells" [Placenta (2009) 1037-1044]. ( 27623544 )
2016
10
A case of choriocarcinoma with concurrent rare presentations: Spontaneous uterine rupture and extensive thoracic spine metastases. ( 27012373 )
2016
11
Chrysophanol induces apoptosis of choriocarcinoma by through regulation of ROS and the AKT and ERK1/2 pathways. ( 27171670 )
2016
12
Effect of hepatitis B virus infection on trophoblast cell line (HTR-8/SVneo) and choriocarcinoma cell line (JEG3) is linked to CD133-2 (AC141) expression. ( 27508045 )
2016
13
Clinical characteristics and prognosis of 272 postterm choriocarcinoma patients at Peking Union Medical College Hospital: a retrospective cohort study. ( 27251425 )
2016
14
Primary Choriocarcinoma of the Bladder: A Case Report and Review of Literature. ( 27793609 )
2016
15
Apigenin Reduces Survival of Choriocarcinoma Cells by Inducing Apoptosis via the PI3K/AKT and ERK1/2 MAPK Pathways. ( 26970256 )
2016
16
Green tea (-)-epigallocatechin gallate induced growth inhibition of human placental choriocarcinoma cells. ( 27208402 )
2016
17
Choriocarcinoma as a cause of hyperthyroidism. ( 28011852 )
2016
18
Ectopic pregnancy with associated gestational choriocarcinoma in a California sea lion (Zalophus californianus). ( 27409239 )
2016
19
Pulmonary Metastatic Choriocarcinoma from a Burned-out Testicular Tumor. ( 27250057 )
2016
20
Involvement of l-type amino acid transporter 1 in the transport of gabapentin into human placental choriocarcinoma cells. ( 27818298 )
2016
21
Colorectal Choriocarcinoma in a Patient with Probable Lynch Syndrome. ( 27965933 )
2016
22
Luteolin Inhibits Proliferation and Induces Apoptosis of Human Placental Choriocarcinoma Cells by Blocking the PI3K/AKT Pathway and Regulating Sterol Regulatory Element Binding Protein Activity. ( 27580988 )
2016
23
Solitary lung metastasis from gestational choriocarcinoma resected six years after hydatidiform mole: A case report. ( 27744215 )
2016
24
Isolation, Culture and Identification of Choriocarcinoma Stem-Like Cells from the Human Choriocarcinoma Cell-Line JEG-3. ( 27606814 )
2016
25
Treatment of Pulmonary Tumor Embolism from Choriocarcinoma: Extracorporeal Membrane Oxygenation as a Bridge through Chemotherapy. ( 27384162 )
2016
26
Choriocarcinoma mimicking chronic thromboembolic pulmonary hypertension. ( 26916795 )
2016
27
Term pregnancy with choriocarcinoma presenting as severe fetal anemia and postpartum hemorrhage. ( 27343330 )
2016
28
Curcumin Suppresses Proliferation and Migration and Induces Apoptosis on Human Placental Choriocarcinoma Cells via ERK1/2 and SAPK/JNK MAPK Signaling Pathways. ( 27580989 )
2016
29
High-dose chemotherapy with autologous peripheral blood stem cell transplantation for choriocarcinoma: A case report and literature review. ( 27900108 )
2016
30
Pituitary metastasis of choriocarcinoma: A case report. ( 26893772 )
2016
31
Primary gestational choriocarcinoma of the vagina: magnetic resonance imaging findings. ( 27095467 )
2016
32
Gynecomastia as a Paraneoplastic Symptom of Choriocarcinoma. ( 27629979 )
2016
33
Pegylated Liposomal Doxorubicin Is an Active Agent for Chemotherapy-Resistant Choriocarcinoma: A Report of Two Cases. ( 27424361 )
2016
34
Ovarian nongestational choriocarcinoma and associated adenocarcinoma with the same germ cell origin determined by a molecular genetic approach: A case report. ( 27484620 )
2016
35
Long non-coding RNA LINC00261 suppresses cell proliferation and invasion and promotes cell apoptosis in human choriocarcinoma. ( 27983929 )
2016
36
Primary Intracranial Choriocarcinoma Located in the Suprasellar Region. ( 27499824 )
2016
37
Primary pulmonary choriocarcinoma in a male that was successfully diagnosed and treated: A case report and review of the literature. ( 28033262 )
2016
38
Primary mediastinal choriocarcinoma with brain metastasis in a female patient. ( 27172760 )
2016
39
Cell-free DNA in pregnancy with choriocarcinoma and coexistent live fetus: A case report. ( 27631219 )
2016
40
Choriocarcinoma in Ongoing Pregnancy Presenting with Intracranial Metastasis. ( 28050451 )
2016
41
Postmolar choriocarcinoma: An independent risk factor for chemotherapy resistance in low-risk gestational trophoblastic neoplasia. ( 26896825 )
2016
42
Choriocarcinoma of unknown origin with multiple organ metastasis and cerebral hemorrhage: A case report and literature review. ( 27313687 )
2016
43
Choriocarcinoma syndrome after resection of primary pulmonary choriocarcinoma: report of a case. ( 27807803 )
2016
44
CLIC1 induces drug resistance in human choriocarcinoma through positive regulation of MRP1. ( 27983917 )
2016
45
Inhibitory Effects of Quercetin on Progression of Human Choriocarcinoma Cells Are Mediated Through PI3K/AKT and MAPK Signal Transduction Cascades. ( 27714811 )
2016
46
Pancreatic and Hepatic Metastasis of an Undiagnosed Choriocarcinoma: An Exceptional Cause of Haemoperitoneum in Young Women - Report of a Rare Case. ( 27920694 )
2016
47
Primary Choriocarcinoma of the Stomach. A Case Report and Review of the Literature. ( 27065697 )
2016
48
Abnormal Presentation of Choriocarcinoma and Literature Review. ( 27482332 )
2016
49
Arteriovenous Fistula Embolization in Suspected Parauterine Choriocarcinoma. ( 27403360 )
2016
50
Clinicopathological analysis of non-gestational ovarian choriocarcinoma: Report of two cases and review of the literature. ( 27073524 )
2016

Variations for Choriocarcinoma

Expression for Choriocarcinoma

Search GEO for disease gene expression data for Choriocarcinoma.

Pathways for Choriocarcinoma

Pathways related to Choriocarcinoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 12.09 ABCG2 CYP11A1 CYP19A1 LNPEP
2
Show member pathways
11.4 CGA CGB3 CGB5
3
Show member pathways
11.28 CGA CYP11A1 CYP19A1
4 10.84 CGA CYP19A1
5 10.83 CGA CYP11A1 CYP19A1
6
Show member pathways
10.67 ABCG2 SLC19A1
7 10.45 CDKN1C CGA CYP19A1

GO Terms for Choriocarcinoma

Cellular components related to Choriocarcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.81 CGA CGB3 CGB5 CGB7 CSH1 CSH2
2 endosome lumen GO:0031904 9.26 CSH1 GH2
3 viral envelope GO:0019031 8.96 ERV3-1 ERVW-1
4 virion GO:0019012 8.62 ERV3-1 ERVW-1

Biological processes related to Choriocarcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.55 CGA CGB3 CGB5 CGB7 LNPEP
2 sterol metabolic process GO:0016125 9.43 CYP11A1 CYP19A1
3 uterus development GO:0060065 9.4 CDKN1C CYP19A1
4 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 9.37 CSH1 GH2
5 negative regulation of organ growth GO:0046621 9.32 CGA SLC6A4
6 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent GO:0002480 9.26 HLA-G LNPEP
7 peptide hormone processing GO:0016486 9.13 CGA CGB3 CGB5
8 female gamete generation GO:0007292 8.8 CGB3 CGB5 CGB7

Molecular functions related to Choriocarcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.1 CGA CGB3 CGB7 CSH1 CSH2 GH2

Sources for Choriocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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