MCID: CHR074
MIFTS: 45

Choriocarcinoma

Categories: Rare diseases, Cancer diseases, Reproductive diseases, Fetal diseases

Aliases & Classifications for Choriocarcinoma

MalaCards integrated aliases for Choriocarcinoma:

Name: Choriocarcinoma 12 50 52 42 14 69
Chorioepithelioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3594
ICD10 33 C58
MeSH 42 D002822
NCIt 47 C2948
UMLS 69 C0008497

Summaries for Choriocarcinoma

MalaCards based summary : Choriocarcinoma, also known as chorioepithelioma, is related to placental site trophoblastic tumor and ovarian mucinous cystadenocarcinoma. An important gene associated with Choriocarcinoma is HOPX (HOP Homeobox), and among its related pathways/superpathways are Glucose / Energy Metabolism and Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors. The drugs Chorionic Gonadotropin and Bleomycin have been mentioned in the context of this disorder. Affiliated tissues include placenta, ovary and testis, and related phenotype is Increased shRNA abundance (Z-score > 2).

Wikipedia : 72 Choriocarcinoma is a malignant, trophoblasticcancer, usually of the placenta. It is characterized by... more...

Related Diseases for Choriocarcinoma

Diseases related to Choriocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 166)
id Related Disease Score Top Affiliating Genes
1 placental site trophoblastic tumor 30.2 CSH1 CSH2
2 ovarian mucinous cystadenocarcinoma 28.8 CGB3 CGB5 CSH1 GPC3 LNPEP
3 mucinous cystadenocarcinoma 22.4 ABCG2 ALPPL2 CGA CGB3 CGB5 CGB7
4 gestational choriocarcinoma 12.2
5 placental choriocarcinoma 11.9
6 choriocarcinoma of the testis 11.9
7 non-gestational choriocarcinoma 11.9
8 choriocarcinoma of ovary 11.9
9 pineal region choriocarcinoma 11.9
10 non-gestational ovarian choriocarcinoma 11.8
11 gestational ovarian choriocarcinoma 11.8
12 fallopian tube gestational choriocarcinoma 11.7
13 childhood choriocarcinoma of the testis 11.7
14 adult central nervous system choriocarcinoma 11.7
15 pediatric cns choriocarcinoma 11.7
16 childhood choriocarcinoma of the ovary 11.7
17 primary non-gestational choriocarcinoma of ovary 11.7
18 pulmonary artery choriocarcinoma 11.7
19 testicular monophasic choriocarcinoma 11.7
20 gestational uterine corpus choriocarcinoma 11.7
21 uterine corpus choriocarcinoma 11.7
22 choriocarcinoma of the central nervous system 11.7
23 gestational trophoblastic tumor 11.4
24 testicular germ cell tumor 11.1
25 normokalemic periodic paralysis 10.8 CGB5 CGB7
26 teratocarcinoma 10.8
27 gestational trophoblastic neoplasm 10.8
28 giant adenofibroma of the breast 10.8 CGA CGB3
29 sertoli cell-only syndrome 10.8 CGA CGB7
30 anterior spinal artery stroke 10.7 CGA CGB5
31 trisomy 2 mosaicism 10.7 CGA CGB7
32 adams-oliver syndrome 6 10.7 CGB5 CYP19A1
33 tetraamelia with ectodermal dysplasia and lacrimal duct abnormalities 10.7 CGA CGB3
34 mitochondrial complex iii deficiency, nuclear type 9 10.7 CGA CYP19A1
35 microcephaly, seizures, and developmental delay 10.7 CGA CGB3 CGB5
36 condrodisplasia punctata rizomélica 10.6 ALPPL2 CGA CYP19A1
37 nipple neoplasm 10.6 CGA CGB3 CGB5
38 ocular hypotension 10.6 CGA CYP19A1
39 toxic encephalopathy 10.6 CGB3 CSH1
40 testicular pure germ cell tumor 10.6 CSH1 CSH2
41 preeclampsia/eclampsia 1 10.6 CGB5 HLA-G LNPEP
42 pfeiffer syndrome 10.5 ALPPL2 CGB5 CYP11A1
43 gingival hypertrophy 10.5 CSH1 CSH2
44 3-methylglutaconic aciduria 10.5 CGA CGB3 CGB5 CGB7
45 uveal melanoma 10.5 CSH1 CSH2
46 agnosia 10.5 CGA CSH1 LNPEP
47 childhood kidney cell carcinoma 10.4 ALPPL2 CGA CGB3 CGB7
48 testicular malignant germ cell cancer 10.4 CSH1 CSH2
49 testicular germ cell cancer 10.4 CSH1 CSH2 HLA-G
50 breast disease 10.4 CSH1 CSH2 CYP19A1

Graphical network of the top 20 diseases related to Choriocarcinoma:



Diseases related to Choriocarcinoma

Symptoms & Phenotypes for Choriocarcinoma

GenomeRNAi Phenotypes related to Choriocarcinoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-103 9.58 HLA-G
2 Increased shRNA abundance (Z-score > 2) GR00366-A-110 9.58 HLA-G
3 Increased shRNA abundance (Z-score > 2) GR00366-A-118 9.58 HLA-G CGB3 CGB5 CGB7
4 Increased shRNA abundance (Z-score > 2) GR00366-A-156 9.58 HLA-G
5 Increased shRNA abundance (Z-score > 2) GR00366-A-178 9.58 HLA-G
6 Increased shRNA abundance (Z-score > 2) GR00366-A-19 9.58 HLA-G
7 Increased shRNA abundance (Z-score > 2) GR00366-A-31 9.58 HLA-G
8 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.58 CGB3 CGB5 CGB7
9 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.58 CGB3 CGB5 CGB7
10 Increased shRNA abundance (Z-score > 2) GR00366-A-7 9.58 HLA-G
11 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.58 HLA-G

Drugs & Therapeutics for Choriocarcinoma

Drugs for Choriocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 156)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Chorionic Gonadotropin Phase 4
2
Bleomycin Approved Phase 2, Phase 3 11056-06-7 5360373
3
Cisplatin Approved Phase 2, Phase 3, Phase 1 15663-27-1 84093 441203 2767
4
Etoposide Approved Phase 2, Phase 3, Phase 1 33419-42-0 36462
5
Lenograstim Approved Phase 2, Phase 3, Phase 1 135968-09-1
6
Paclitaxel Approved, Vet_approved Phase 2, Phase 3, Phase 1 33069-62-4 36314
7
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
8
Mechlorethamine Approved Phase 3,Phase 1,Phase 2 51-75-2 4033
9
Oxaliplatin Approved, Investigational Phase 3,Phase 1 61825-94-3 5310940 9887054 43805 6857599
10
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 50-02-2 5743
11
Mesna Approved Phase 3,Phase 1,Phase 2 3375-50-6 598
12
Dactinomycin Approved Phase 3 50-76-0 2019 457193
13
Methotrexate Approved Phase 3,Phase 2 1959-05-2, 59-05-2 126941
14
Palivizumab Approved, Investigational Phase 3 188039-54-5
15
Ribavirin Approved Phase 3 36791-04-5 37542
16
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
17
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 468682 2826718
18
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
19
Captopril Approved Phase 3 62571-86-2 44093
20
Cyclophosphamide Approved, Investigational Phase 3,Phase 1 50-18-0, 6055-19-2 2907
21
Fluconazole Approved Phase 3 86386-73-4 3365
22
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
23
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
24
Levoleucovorin Approved Phase 3,Phase 2,Phase 1 68538-85-2
25
Diphenhydramine Approved Phase 3 58-73-1, 147-24-0 3100
26
Promethazine Approved Phase 3 60-87-7 4927
27
Vinblastine Approved Phase 3 865-21-4 13342 241903
28
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
29
leucovorin Approved, Nutraceutical Phase 3,Phase 2,Phase 1 58-05-9 143 6006
30 Albumin-Bound Paclitaxel Phase 2, Phase 3, Phase 1
31 Anti-Bacterial Agents Phase 2, Phase 3, Phase 1
32 Antibiotics, Antitubercular Phase 2, Phase 3
33 Antimitotic Agents Phase 2, Phase 3, Phase 1
34 Antineoplastic Agents, Phytogenic Phase 2, Phase 3, Phase 1
35 Etoposide phosphate Phase 2, Phase 3, Phase 1
36 Topoisomerase Inhibitors Phase 2, Phase 3, Phase 1
37 Alkylating Agents Phase 3,Phase 1,Phase 2
38 Isophosphamide mustard Phase 3,Phase 1,Phase 2
39 Anti-Infective Agents Phase 3,Phase 1,Phase 2
40 Antimetabolites Phase 3,Phase 2,Phase 1
41 Antimetabolites, Antineoplastic Phase 3,Phase 2,Phase 1
42 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
43 Antiviral Agents Phase 3,Phase 1,Phase 2
44 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
45 BB 1101 Phase 3,Phase 1,Phase 2
46 Dexamethasone acetate Phase 3,Phase 1,Phase 2 1177-87-3
47 Antirheumatic Agents Phase 3,Phase 2,Phase 1
48 Dermatologic Agents Phase 3,Phase 2
49 Folic Acid Antagonists Phase 3,Phase 2
50 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 67)

id Name Status NCT ID Phase Drugs
1 Conformation of Beta Human Chorionic Gonadotropin During Chemotherapy for Choriocarcinoma Unknown status NCT00294177 Phase 4
2 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
3 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
4 Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia Completed NCT00003702 Phase 3 Methotrexate
5 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
6 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
7 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
8 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
9 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
10 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3 cisplatin;etoposide;ifosfamide
11 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide
12 Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain Completed NCT00293358 Phase 3 carboplatin;cisplatin;etoposide phosphate;ifosfamide
13 Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3 Bleomycin;Carboplatin;Cisplatin;Etoposide
14 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3 paclitaxel;ifosfamide;cisplatin;pegylated G-CSF;G-CSF;carboplatin;etoposide phosphate
15 Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia Active, not recruiting NCT01535053 Phase 3 Leucovorin Calcium;Methotrexate
16 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Active, not recruiting NCT00053352 Phase 3 cisplatin;etoposide
17 Rescue Regimen and High Dose Methotrexate in Management of Presistent Gestational Trophoplastic Neoplasia Not yet recruiting NCT03280979 Phase 2, Phase 3 rescue regimen;high dose methotrxate
18 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
19 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2 cisplatin;gemcitabine hydrochloride;ifosfamide;paclitaxel
20 A Trial for Patients With Gestational Trophoblastic Disease Completed NCT00190918 Phase 2 Pemetrexed
21 Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors Completed NCT00467051 Phase 2 paclitaxel;carboplatin;ifosfamide
22 Second Curettage in Treating Patients With Persistent Non-metastatic Gestational Trophoblastic Tumors Completed NCT00521118 Phase 2
23 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2 sunitinib malate
24 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
25 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
26 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
27 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
28 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
29 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
30 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2 cisplatin;etoposide
31 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
32 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2 carboplatin;cisplatin;etoposide phosphate;vincristine sulfate
33 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2 ixabepilone
34 Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Metastatic Testicular Cancer Completed NCT00004077 Phase 2 cisplatin;ifosfamide;paclitaxel
35 Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors Completed NCT00047320 Phase 2 carboplatin;etoposide;ifosfamide;thiotepa
36 Cisplatin and Etoposide Prior to Radiation Therapy in Treating Patients With CNS Tumors Completed NCT00002472 Phase 2 cisplatin;etoposide
37 Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors Completed NCT00005955 Phase 2 temozolomide
38 Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN) Recruiting NCT02664961 Phase 2 TRC105;Bevacizumab
39 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
40 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel;thiotepa;Mesna
41 Single Patient Treatment Protocol of TRC105 Combined With Standard-dose Bevacizumab for a Single Patient With Metastatic And Refractory Choriocarcinoma Active, not recruiting NCT02396511 Phase 2
42 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
43 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1 ipilimumab;therapeutic allogeneic lymphocytes
44 Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors Completed NCT00281944 Phase 1 oxaliplatin;fluorouracil;leucovorin calcium
45 Sunitinib in Treating Young Patients With Refractory Solid Tumors Completed NCT00387920 Phase 1 sunitinib malate
46 Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00929903 Phase 1 pazopanib hydrochloride
47 Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
48 Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma Completed NCT00994500 Phase 1 vorinostat;bortezomib
49 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
50 Safety and Tolerability Study of AZD2171 in Combination With AZD0530 in Patients With Advanced Solid Tumours Completed NCT00475956 Phase 1 AZD2171;AZD0530

Search NIH Clinical Center for Choriocarcinoma

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: choriocarcinoma

Genetic Tests for Choriocarcinoma

Anatomical Context for Choriocarcinoma

MalaCards organs/tissues related to Choriocarcinoma:

39
Placenta, Ovary, Testis, Lung, Brain, Bone, Bone Marrow

Publications for Choriocarcinoma

Articles related to Choriocarcinoma:

(show top 50) (show all 1101)
id Title Authors Year
1
Chemotherapy during Pregnancy: Cases of Hodgkin's and Non-Hodgkin's Lymphoma, Chronic Myeloid Leukemia, Breast Cancer, Nasopharyngeal Cancer, and Choriocarcinoma. ( 28700986 )
2017
2
A gestational choriocarcinoma of the ovary diagnosed by DNA polymorphic analysis: a case report and systematic review of the literature. ( 28728581 )
2017
3
Antagonism of EG-VEGF receptors as targeted therapy for choriocarcinoma progression in vitro and in vivo. ( 28899975 )
2017
4
Primary Gastric Choriocarcinoma Presenting as a Pregnancy of Unknown Location. ( 28079767 )
2017
5
Aberrantly Expressed SALL4 Promotes Cell Proliferation via I^-Catenin/c-Myc Pathway in Human Choriocarcinoma Cells. ( 28639477 )
2017
6
Primary non-gestational choriocarcinoma of the uterine cervix with metaplastic transformation from adenocarcinoma: a case report. ( 28830246 )
2017
7
c-Rel Promotes Invasion of Choriocarcinoma Cells via PI3K/AKT Signaling. ( 28259870 )
2017
8
Activation of Peroxisome Proliferator-Activated Receptor Gamma and Disruption of Progesterone Synthesis of 2-Ethylhexyl Diphenyl Phosphate in Human Placental Choriocarcinoma Cells: Comparison with Triphenyl Phosphate. ( 28282128 )
2017
9
Benzo(a)pyrene induced cell cycle arrest and apoptosis in human choriocarcinoma cancer cells through reactive oxygen species-induced endoplasmic reticulum-stress pathway. ( 28673838 )
2017
10
Metastatic gestational choriocarcinoma: a masquerader in obstetrics. ( 28550508 )
2017
11
Choriocarcinoma in Women: Analysis of a Case Series With Genotyping. ( 28877059 )
2017
12
Silibinin stimluates apoptosis by inducing generation of ROS and ER stress in human choriocarcinoma cells. ( 28657208 )
2017
13
Erratum: High-dose chemotherapy with autologous peripheral blood stem cell transplantation for choriocarcinoma: A case report and literature review. ( 28781822 )
2017
14
Gestational choriocarcinoma complicated by infective endocarditis during chemotherapy. ( 28217736 )
2017
15
An unusual pulmonary metastatic manifestation of gestational choriocarcinoma: A diagnostic dilemma. ( 28869244 )
2017
16
Case Report: Multiple hemorrhagic metastases to the brain from primary lung choriocarcinoma. ( 28794859 )
2017
17
Collision tumor of choriocarcinoma and small cell carcinoma of the stomach: A case report. ( 28709051 )
2017
18
An extremely rare case of postpartum gestational choriocarcinoma with long-term survival. ( 28777426 )
2017
19
Complete Serologic Response to Pembrolizumab in a Woman With Chemoresistant Metastatic Choriocarcinoma. ( 28742453 )
2017
20
Daidzein inhibits choriocarcinoma proliferation by arresting cell cycle at G1 phase through suppressing ERK pathway in vitro and in vivo. ( 28849226 )
2017
21
Role of chemotherapy and thrombolysis in treatment of choriocarcinoma accompanied with pulmonary embolism: A case report with literature review. ( 28885339 )
2017
22
Gestational choriocarcinoma associated with a germline TP53 mutation. ( 28477316 )
2017
23
Prognosis of gestational choriocarcinoma diagnosed incidentally during laparoscopy for a presumed cornual pregnancy: a report of five cases. ( 28607811 )
2017
24
Treatment of Human Placental Choriocarcinoma Cells with Formaldehyde and Benzene Induced Growth and Epithelial Mesenchymal Transition via Induction of an Antioxidant Effect. ( 28758930 )
2017
25
miR-21 Is Overexpressed in Hydatidiform Mole Tissues and Promotes Proliferation, Migration, and Invasion in Choriocarcinoma Cells. ( 27922982 )
2017
26
Pitfalls in Diagnosis and Management of Testicular Choriocarcinoma Metastatic to the Brain: Report of 2 Cases and Review of Literature. ( 28712904 )
2017
27
Postmenopausal choriocarcinoma: a rare case report and review of the literature. ( 28816932 )
2017
28
Fatty acid-binding protein3 expression in BeWo cells, a human placental choriocarcinoma cell line. ( 28515017 )
2017
29
Myricetin suppresses invasion and promotes cell death in human placental choriocarcinoma cells through induction of oxidative stress. ( 28428076 )
2017
30
Acquired Pulmonary Arteriovenous Fistula within Metastasis from Choriocarcinoma: A Case Report. ( 28878648 )
2017
31
Primary pulmonary choriocarcinoma in a male that was successfully diagnosed and treated: A case report and review of the literature. ( 28033262 )
2016
32
Clinicopathological analysis of non-gestational ovarian choriocarcinoma: Report of two cases and review of the literature. ( 27073524 )
2016
33
Effect of hepatitis B virus infection on trophoblast cell line (HTR-8/SVneo) and choriocarcinoma cell line (JEG3) is linked to CD133-2 (AC141) expression. ( 27508045 )
2016
34
Pancreatic and Hepatic Metastasis of an Undiagnosed Choriocarcinoma: An Exceptional Cause of Haemoperitoneum in Young Women - Report of a Rare Case. ( 27920694 )
2016
35
Cell-free DNA in pregnancy with choriocarcinoma and coexistent live fetus: A case report. ( 27631219 )
2016
36
Impact of Axis of GHRH and GHRH Receptor on Cell Viability and Apoptosis of the Placental Choriocarcinoma Cell Line. ( 26917260 )
2016
37
Disseminated gestational choriocarcinoma presenting with hepatic and uveal metastases, hook effect, and choriocarcinoma syndrome. ( 28104943 )
2016
38
Postmolar choriocarcinoma: An independent risk factor for chemotherapy resistance in low-risk gestational trophoblastic neoplasia. ( 26896825 )
2016
39
Chrysophanol induces apoptosis of choriocarcinoma by through regulation of ROS and the AKT and ERK1/2 pathways. ( 27171670 )
2016
40
Green tea (-)-epigallocatechin gallate induced growth inhibition of human placental choriocarcinoma cells. ( 27208402 )
2016
41
Recovery from Choriocarcinoma Syndrome Associated with a Metastatic Extragonadal Germ Cell Tumor Hemorrhage. ( 27403124 )
2016
42
Gestational choriocarcinoma with renal and pulmonary metastases lacking a primary uterine origin. ( 28040140 )
2016
43
Long non-coding RNA LINC00261 suppresses cell proliferation and invasion and promotes cell apoptosis in human choriocarcinoma. ( 27983929 )
2016
44
Primary Intracranial Choriocarcinoma Located in the Suprasellar Region. ( 27499824 )
2016
45
Treatment of Pulmonary Tumor Embolism from Choriocarcinoma: Extracorporeal Membrane Oxygenation as a Bridge through Chemotherapy. ( 27384162 )
2016
46
Primary gestational choriocarcinoma of the vagina: magnetic resonance imaging findings. ( 27095467 )
2016
47
Isolation, Culture and Identification of Choriocarcinoma Stem-Like Cells from the Human Choriocarcinoma Cell-Line JEG-3. ( 27606814 )
2016
48
A case of choriocarcinoma with concurrent rare presentations: Spontaneous uterine rupture and extensive thoracic spine metastases. ( 27012373 )
2016
49
Involvement of l-type amino acid transporter 1 in the transport of gabapentin into human placental choriocarcinoma cells. ( 27818298 )
2016
50
Inhibitory Effects of Quercetin on Progression of Human Choriocarcinoma Cells Are Mediated Through PI3K/AKT and MAPK Signal Transduction Cascades. ( 27714811 )
2016

Variations for Choriocarcinoma

Expression for Choriocarcinoma

Search GEO for disease gene expression data for Choriocarcinoma.

Pathways for Choriocarcinoma

GO Terms for Choriocarcinoma

Cellular components related to Choriocarcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.36 ALPPL2 CGA CGB3 CGB5 CGB7 CSH1
2 endosome lumen GO:0031904 9.26 CSH1 GH2
3 viral envelope GO:0019031 9.16 ERV3-1 ERVW-1
4 virion GO:0019012 8.96 ERV3-1 ERVW-1

Biological processes related to Choriocarcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.55 CGA CGB3 CGB5 CGB7 LNPEP
2 sterol metabolic process GO:0016125 9.37 CYP11A1 CYP19A1
3 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 9.32 CSH1 GH2
4 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent GO:0002480 9.26 HLA-G LNPEP
5 peptide hormone processing GO:0016486 9.13 CGA CGB3 CGB5
6 female gamete generation GO:0007292 8.8 CGB3 CGB5 CGB7

Molecular functions related to Choriocarcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.1 CGA CGB3 CGB7 CSH1 CSH2 GH2

Sources for Choriocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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