Chorioretinitis disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Summaries for Chorioretinitis

Sources:
⁶⁴Wikipedia, ³²MalaCards
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Wikipedia:⁶⁴ }} Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and... more...

MalaCards based summary: Chorioretinitis, also known as retinochoroiditis, is related to uveitis and tuberculosis. An important gene associated with Chorioretinitis is RBP3 (retinol binding protein 3, interstitial), and among its related pathways are Visual Cycle in Retinal Rods and Diseases associated with visual transduction. The compounds glutamate and vitamin a have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and liver, and related mouse phenotype nervous system.

Aliases & Classifications for Chorioretinitis

Sources:
⁹Disease Ontology, ⁴²NIH Rare Diseases, ¹¹DISEASES, ⁴⁴Novoseek, ⁶¹UMLS, ⁵⁶SNOMED-CT, ³⁴MeSH, ²⁸ICD9CM
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Chorioretinitis, Aliases & Descriptions:

Name: Chorioretinitis ⁹ ⁴² ¹¹ ⁴⁴ ⁶¹

Retinochoroiditis ⁹ ⁶¹

Other and Unspecified Forms of Chorioretinitis and Retinochoroiditis ⁹

Other Chorioretinitis and Retinochoroiditis ⁹

Retinochoroiditis Nos Disorder ⁹

Retinitis and Chorioretinitis ⁹

Chorioretinitis, Unspecified ⁹

Other Chorioretinitis ⁹

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Eye diseases

External Ids:

Disease Ontology⁹ DOID:8886

MeSH³⁴ D002825

SNOMED-CT⁵⁶ 270531006, 193432007, 46627006

ICD9CM²⁸ 363.20

UMLS⁶¹ C0008513

Related Diseases for Chorioretinitis

Sources:
¹⁸GeneCards, ¹⁹GeneDecks
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Diseases related to Chorioretinitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50) (show all 253)

id	Related Disease	Score	Top Affiliating Genes
1	uveitis	30.3	RBP3, SAG
2	tuberculosis	30.0	CX3CL1, SAG
3	vasculitis	29.8	SAG, RBP3
4	retinoblastoma	29.5	RBP3, SAG
5	retinitis	10.6
6	retinochoroidal coloboma	10.6
7	toxoplasmosis	10.5
8	aicardi syndrome	10.5
9	coloboma	10.4
10	pigmented paravenous chorioretinal atrophy	10.4
11	retinal vein occlusion	10.4
12	central retinal vein occlusion	10.4
13	progressive bifocal chorioretinal atrophy	10.4
14	microcephaly	10.4
15	chorioretinal scar	10.4
16	choroiditis	10.4
17	west nile virus	10.4
18	congenital toxoplasmosis	10.3
19	disseminated chorioretinitis	10.3
20	focal chorioretinitis	10.3
21	blindness	10.3
22	encephalitis	10.3
23	retinal detachment	10.3
24	syphilis	10.3
25	lymphedema	10.2
26	subacute sclerosing panencephalitis	10.2
27	herpes simplex	10.2
28	peripheral focal chorioretinitis	10.2
29	keratitis	10.2
30	night blindness	10.2
31	birdshot chorioretinopathy	10.2
32	boucher neuhauser syndrome	10.2
33	chronic granulomatous disease	10.1
34	onchocerciasis	10.1
35	lymphocytic choriomeningitis	10.1
36	hypogonadism	10.1
37	panuveitis	10.1
38	joubert syndrome with oculorenal anomalies	10.1
39	cytomegalovirus infection	10.1
40	sveinsson choreoretinal atrophy	10.1
41	microcornea, myopic chorioretinal atrophy, and telecanthus	10.1
42	neuroretinitis	10.1
43	vogt-koyanagi-harada disease	10.1
44	joubert syndrome	10.1
45	histoplasmosis	10.1
46	myopia	10.1
47	neuritis	10.1
48	optic neuritis	10.1
49	cleft lower lip cleft lateral canthi chorioretinal	10.1
50	coloboma chorioretinal cerebellar vermis aplasia	10.1

Graphical network of the top 20 diseases related to Chorioretinitis:

Symptoms for Chorioretinitis

Drugs & Therapeutics for Chorioretinitis

Sources:
⁴¹NIH Clinical Center, ⁶ClinicalTrials, ⁶¹UMLS, ⁴⁰NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Chorioretinitis

Search NIH Clinical Center for Chorioretinitis

Genetic Tests for Chorioretinitis

Anatomical Context for Chorioretinitis

Sources:
³²MalaCards
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MalaCards organs/tissues related to Chorioretinitis:

³²

Retina, Eye, Liver, Brain, Spinal cord, Kidney, Testes, B cells

Animal Models for Chorioretinitis or affiliated genes

Sources:
³⁶MGI
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MGI Mouse Phenotypes related to Chorioretinitis:

³⁶

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	nervous system phenotype	MP:0003631	8.5	RBP3, CX3CL1, SAG

Publications for Chorioretinitis

Sources:
⁵¹PubMed
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Articles related to Chorioretinitis:

(show top 50) (show all 430)

id	Title	Authors	Year
1	The Evolution of Untreated Acute Syphilitic Posterior Placoid Chorioretinitis Captured by Multimodal Retinal Imaging. (25347827)	Armstrong B.K.... Garg S.J.	2014
2	Chorioretinitis as the first sign of acquired toxoplasmosis transmitted from donor following kidney transplantation: case report and review of the literature. (23323579)	Filloy A.... FernA!ndez-Lorente L.	2013
3	Enhanced depth imaging spectral domain optical coherence tomography in syphilitic chorioretinitis. (25391125)	Say E.A.... Ulrich J.N.	2013
4	Fulminant chorioretinitis and papillitis secondary to coxsackievirus B presenting as acute posterior multifocal placoid pigment epitheliopathy with positive response to intravenous immunoglobulin. (25391111)	Hollsten J.E.... Kay C.N.	2013
5	Levofloxacin-associated panuveitis with chorioretinal lesions. (23044958)	Butler N.J.... Suhler E.B.	2012
6	Chorioretinitis as a first sign of SSPE. (22473286)	Yimenicioglu S.... Ekici A.	2012
7	Relentless placoid chorioretinitis. (22954946)	Mirza R.G.... Jampol L.M.	2012
8	Subacute sclerosing panencephalitis masquerading as toxoplasmosis chorioretinitis. (22560432)	Chawla A.... Jain S.	2012
9	Microcornea with myopic chorioretinal atrophy, telecanthus and posteriorly-rotated ears: a distinct clinical syndrome. (22686506)	Khan A.O.	2012
10	Reactivation West Nile virus infection-related chorioretinitis. (22784261)	Beardsley R.... McCannel C.	2012
11	Cryptococcus gattii chorioretinitis in a ferret. (21733068)	Ropstad E.O.... Martorell J.	2011
12	Clinical presentation and outcome of chorioretinitis sclopetaria: a case series study. (19524909)	Ahmadabadi M.N.... Alimardani A.	2010
13	Cryptococcal chorioretinitis with immune reconstitution inflammatory syndrome. (19831560)	Shulman J.... Sanjana V.	2009
14	Laser chorioretinal venous anastomosis for progressive nonischemic central retinal vein occlusion. (16515021)	Chen C.H.... Kuo H.K.	2005
15	Low levels of pigment epithelium-derived factor in highly myopic eyes with chorioretinal atrophy. (16310484)	Ogata N.... Matsumura M.	2005
16	Use of PCR to diagnose Toxoplasma gondii chorioretinitis in eyes with severe vitritis. (15807829)	Okhravi N.... Lightman S.	2005
17	Progressive pigmentation of chorioretinal lesions in aicardi syndrome. (15136335)	Ospina L.H.... McCormick A.Q.	2004
18	A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration). (15016762)	Fossdal R.... Stefansson K.	2004
19	Vitritis and chorioretinitis in a patient with West Nile virus infection. (12583786)	Bains H.S.... Parnell J.R.	2003
20	Evaluation of vitrectomy specimens and chorioretinal biopsies in the diagnosis of primary intraocular lymphoma in patients with Masquerade syndrome. (14605902)	Coupland S.E.... Stein H.	2003
21	Effect of peripapillary chorioretinal atrophy on GDx parametersin patients with degenerative myopia. (12427231)	Bozkurt B.... Karaagaoglu E.	2002
22	Clinical picture: tuberculous chorioretinitis. (11356435)	Lanzafame M.... Parrinello A.	2001
23	Chorioretinitis after keratitis caused by Acanthamoeba: case report and review of the literature. (11733264)	Moshari A.... McEvoy P.L.	2001
24	Chorioretinitis sclopetaria from BB ex memoria. (11300639)	Otto C.S.... Krolicki T.J.	2001
25	Coxsackievirus B4 as a cause of adult chorioretinitis. (10088751)	Kadrmas E.F.... Buzney S.M.	1999
26	Peripheral multifocal chorioretinitis with panuveitis: clinical and immunogenetic characterization in older patients. (9646091)	NAPlle B.... Westphal E.	1998
27	Chorioretinitis following liver transplantation: detection of Toxoplasma gondii in aqueous humor. (8825000)	Blanc-Jouvan M.... Ducerf C.	1996
28	Evisceration of the eye in a renal transplant recipient with cytomegalovirus chorioretinitis. (8739295)	BaA9Asil N.... CaA9lar S.	1996
29	Monolateral chorioretinitis with multiple foci in one case of Lyme disease. (8363293)	Niutta A.... Palombi E.	1993
30	Chorioretinitis as a possible very early manifestation of subacute sclerosing panencephalitis. (1953517)	Zagami A.S.... Lethlean A.K.	1991
31	Experimental ocular onchocerciasis in cynomolgus monkeys. IV. Chorioretinitis elicited by Onchocerca volvulus microfilariae. (2016131)	Semba R.D.... Taylor H.R.	1991
32	Shiny multifocal chorioretinitis with papillitis. (2627097)	Cunha De Souza E.... Jalkh A.E.	1989
33	Syphilitic chorioretinitis. (2818290)	Friberg T.R.	1989
34	Experimental ocular onchocerciasis in cynomolgus monkeys. III. Roles of IgG and IgE antibody and autoantibody and cell-mediated immunity in the chorioretinitis elicited by intravitreal Onchocerca lienalis microfilariae. (3175465)	Donnelly J.J.... Rockey J.H.	1988
35	Unusual central chorioretinitis as the first manifestation of early secondary syphilis. (3344784)	de Souza E.C.... Schepens C.L.	1988
36	Chorioretinal dysplasia in young subjects with Wagner's hereditary vitreoretinal degeneration. (7228506)	Van Nouhuys C.E.	1981
37	Chorioretinitis of the newborn with herpes simplex virus type 1. Report of a case. (232606)	Reersted P.... Hansen B.	1979
38	Acute macular chorioretinitis associated with scorpion sting: a case report. (622733)	Heckenlively J.R.... Pearlman J.T.	1978
39	Cryptococcal chorioretinitis: a case report. (326307)	Chapman-Smith J.S.	1977
40	Autoimmune chorioretinitis in rhesus monkeys. (4974166)	Lerner E.M.... Von Sallmann L.	1968
41	Acquired toxoplasmic chorioretinitis. (6040929)	Spaulding A.G.... Font R.L.	1967
42	Experimental Candida albicans chorioretinitis treated by laser. (6019529)	Santos R.... JuA!rez P.	1967
43	An evaluation of the etiologic survey in chorioretinitis. (13705282)	GILES C.L.... Lewis A.	1961
44	Central angiospastic retinopathy and central serous chorioretinitis. (13394600)	WAGENER H.P.	1957
45	New observations in generalized cytomegalic-inclusion disease of the newborn: report of a case with chorioretinitis. (13477392)	GUYTON T.B.... BECKER M.H.	1957
46	Toxoplasmic chorioretinitis in the adult. (13228434)	WAGENER H.P.	1955
47	Primary chorioretinal aberrations with night blindness; treatment and conclusions. (15443029)	FRALICK F.B.	1950
48	Chorioretinitis juxtapapillaris, Jensen's disease. (18870553)	BULLWINKEL H.G.	1948
49	Chorioretinitis sclopetaria. (18905687)	EUBANK W.R.	1948
50	Chorioretinitis due to toxoplasmosis. (18934210)	Strong J.	1948

Genes related to Chorioretinitis

Sources:
¹⁸GeneCards, ¹antibodies-online, ⁴⁵Novus Biologicals
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Genes related to Chorioretinitis:

- Elite gene

id	Symbol	Description	Score	Implication
1	RBP3	retinol binding protein 3, interstitial	23.29	GeneCards inferred via : Disorders (show sections)
2	SAG	S-antigen; retina and pineal gland (arrestin)	16.63	GeneCards inferred via : Disorders (show sections)
3	CX3CL1	chemokine (C-X3-C motif) ligand 1	9.96	GeneCards inferred via : Disorders (show sections)

Products for genes related to Chorioretinitis disease:

id	Company	Proteins	Lysates	Antibodies	Kits and Assays
1	Antibodies-online	3	-	3	3
2	Novus Biologicals	3	1	3	-

Variations for Chorioretinitis

Expression for genes affiliated with Chorioretinitis

Sources:
²BioGPS, ¹⁶Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Chorioretinitis

Search GEO for disease gene expression data for Chorioretinitis.

Pathways for genes affiliated with Chorioretinitis

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⁴⁹PathCards, ⁵²QIAGEN, ⁵⁴Reactome
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Pathways related to Chorioretinitis according to GeneCards/GeneDecks:

id	Super pathways (with members indented)	Score	Top Affiliating Genes
1	Visual Cycle in Retinal Rods⁵²	9.0	RBP3, SAG
2	Diseases associated with visual transduction⁵⁴ Show member pathways Retinoid metabolism and transport⁵⁴ Biosynthesis of A2E, implicated in retinal degradation⁵⁴ The retinoid cycle in cones (daylight vision)⁵⁴ Visual phototransduction⁵⁴ Retinoid cycle disease events⁵⁴	9.0	RBP3, SAG
3	Signaling by GPCR⁵⁴ Show member pathways GPCR downstream signaling⁵⁴ Signal Transduction⁵⁴	8.5	RBP3, CX3CL1, SAG

Compounds for genes affiliated with Chorioretinitis

Sources:
⁴⁴Novoseek, ²⁵HMDB, ¹²DrugBank
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Compounds related to Chorioretinitis according to GeneCards/GeneDecks:

id	Compound	Score	Top Affiliating Genes
1	glutamate⁴⁴	9.1	CX3CL1, SAG
2	vitamin a⁴⁴ ²⁵ ¹²	11.1	RBP3, SAG
3	retinoid⁴⁴	9.0	RBP3, SAG
4	glutamine⁴⁴	8.9	SAG, RBP3
5	leucine⁴⁴	8.7	RBP3, SAG

GO Terms for genes affiliated with Chorioretinitis

Sources:
¹⁷Gene Ontology
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Biological processes related to Chorioretinitis according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	visual perception	GO:007601	9.0	RBP3, SAG
2	phototransduction, visible light	GO:007603	8.7	RBP3, SAG

Products for genes affiliated with Chorioretinitis

Antibodies
Proteins
Lysates

Antibodies
Proteins
Kits and Assays

Sources for Chorioretinitis

¹antibodies-online

²BioGPS

³BitterDB

⁴CDC

⁵Cell Signaling Technology

⁶ClinicalTrials

⁷Clinvar

⁸dbSNP

⁹Disease Ontology

¹⁰diseasecard

¹¹DISEASES

¹²DrugBank

¹³EMD Millipore

¹⁴ExPASy

¹⁵FMA

¹⁶Gene Expression Omnibus DataSets

¹⁷Gene Ontology

¹⁸GeneCards

¹⁹GeneDecks

²⁰GeneReviews

²¹GeneTests

²²Genetics Home Reference

²³GTR

²⁴HGMD

²⁵HMDB

²⁶ICD10

²⁷ICD10 via Orphanet

²⁸ICD9CM

²⁹IUPHAR

³⁰KEGG

³¹LifeMap Discovery®

³²MalaCards

³³MedlinePlus

³⁴MeSH

³⁵MESH via Orphanet

³⁶MGI

³⁷NCBI BioSystems Database

³⁸NCBI Bookshelf

³⁹NCIt

⁴⁰NDF-RT

⁴¹NIH Clinical Center

⁴²NIH Rare Diseases

⁴³NINDS

⁴⁴Novoseek

⁴⁵Novus Biologicals

⁴⁶OMIM

⁴⁷OMIM via Orphanet

⁴⁸Orphanet

⁴⁹PathCards

⁵⁰PharmGKB

⁵¹PubMed

⁵²QIAGEN

⁵³R&D Systems

⁵⁴Reactome

⁵⁵SinoBiological

⁵⁶SNOMED-CT

⁵⁷SNOMED-CT via Orphanet

⁵⁸The Human Phenotype Ontology

⁵⁹Thomson Reuters

⁶⁰Tocris Bioscience

⁶¹UMLS

⁶²UMLS via Orphanet

⁶³UniProtKB/Swiss-Prot

⁶⁴Wikipedia

MCID: CHR078 MIFTS: 44	Chorioretinitis malady Rare diseases, Eye diseases categories
3 genes, 8 tissues, 253 related diseases, clinical trials Download this MalaCard Expand all tables

Chorioretinitis malady