MCID: CHR078
MIFTS: 45

Chorioretinitis malady

Summaries for Chorioretinitis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina... more...

MalaCards: Chorioretinitis, also known as other and unspecified forms of chorioretinitis and retinochoroiditis, is related to retinitis and chorioretinal scar. An important gene associated with Chorioretinitis is TEAD1 (TEA domain family member 1 (SV40 transcriptional enhancer factor)), and among its related pathways are the visual cycle I (vertebrates) and Visual phototransduction. The compounds 11-cis-retinol and copper have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and liver, and related mouse phenotypes are pigmentation and homeostasis/metabolism.

Aliases & Classifications for Chorioretinitis

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8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH
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Aliases & Descriptions:

chorioretinitis 8 42 10 44 60
other and unspecified forms of chorioretinitis and retinochoroiditis 8
other chorioretinitis and retinochoroiditis 8
retinochoroiditis nos disorder 8
retinitis and chorioretinitis 8
chorioretinitis, unspecified 8
other chorioretinitis 8
retinochoroiditis 8


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Disease Ontology8 DOID:8886
ICD9CM27 363.20
MeSH34 D002825

Related Diseases for Chorioretinitis

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17GeneCards, 18GeneDecks
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Diseases related to Chorioretinitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 237)
idRelated DiseaseScoreTop Affiliating Genes
1retinitis30.8SAG
2chorioretinal scar30.5JMJD6
3uveitis30.4RBP3, SAG
4night blindness30.2SAG, RPE65
5cone-rod dystrophy 229.9PRPH2, RPE65
6gyrate atrophy29.6OAT
7retinal disease29.6RPE65, ROM1, SAG, CRB1, RBP3, PRPH2
8toxoplasmosis10.5
9aicardi syndrome10.4
10central retinal vein occlusion10.4
11retinal vein occlusion10.4
12coloboma10.3
13microcephaly10.3
14progressive bifocal chorioretinal atrophy10.3
15disseminated chorioretinitis10.3
16choroiditis10.3
17retinochoroidal coloboma10.3
18focal chorioretinitis10.3
19congenital toxoplasmosis10.2
20retinal detachment10.2
21syphilis10.2
22subacute sclerosing panencephalitis10.2
23encephalitis10.2
24herpes simplex10.2
25peripheral focal chorioretinitis10.1
26keratitis10.1
27lymphedema10.1
28tuberculosis10.1
29pigmented paravenous chorioretinal atrophy10.1
30chronic granulomatous disease10.1
31lymphocytic choriomeningitis10.1
32onchocerciasis10.1
33panuveitis10.1
34neuroretinitis10.0
35macular retinal edema10.0
36vogt-koyanagi-harada disease10.0
37joubert syndrome10.0
38arthritis10.0
39histoplasmosis10.0
40myopia10.0
41neuritis10.0
42optic neuritis10.0
43joubert syndrome with oculorenal anomalies10.0
44birdshot chorioretinopathy10.0
45lymphedema, microcephaly and chorioretinopathy syndrome10.0
46cleft lower lip cleft lateral canthi chorioretinal10.0
47wagner syndrome10.0
48sveinsson choreoretinal atrophy10.0
49microcornea, myopic chorioretinal atrophy, and telecanthus10.0
50peripheral retinal degeneration10.0ROM1

Graphical network of the top 20 diseases related to Chorioretinitis:



Diseases related to chorioretinitis

Clinical Features for Chorioretinitis

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Drugs & Therapeutics for Chorioretinitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search CenterWatch for Chorioretinitis

Genetic Tests for Chorioretinitis

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Anatomical Context for Chorioretinitis

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32MalaCards
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MalaCards organs/tissues related to Chorioretinitis:

32
Retina, Eye, Liver, Brain, Spinal cord, Kidney, Testes, B cells

Animal Models for Chorioretinitis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Chorioretinitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.4C1QTNF5, RPE65, FOXC1, CRB1, PRPH2, OAT
2MP:00053768.8JMJD6, FOXC1, CRB1, MT2A, MT3, HCCS
3MP:00053918.7C1QTNF5, RPE65, JMJD6, SAG, FOXC1, CRB1
4MP:00053858.7C1QTNF5, JMJD6, FOXC1, MT2A, PRPH2, HCCS
5MP:00036318.0OAT, C1QTNF5, RPE65, JMJD6, SAG, FOXC1

Publications for Chorioretinitis

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50PubMed
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Articles related to Chorioretinitis:

(show top 50)    (show all 407)
idTitleAuthorsYear
1
Correlation between aqueous flare and chorioretinal neovascularization in age-related macular degeneration following intravitreal bevacizumab injections. (24209785)
2014
2
Reactivation West Nile virus infection-related chorioretinitis. (22784261)
2012
3
OCT findings in birdshot chorioretinitis: a glimpse into retinal disease evolution. (22909176)
2012
4
Use of intravitreous bevacizumab to treat macular edema in West Nile virus chorioretinitis. (22411674)
2012
5
Imaging findings in bilateral macular chorioretinitis due to subacute sclerosing panencephalitis. (21766746)
2011
6
Wide-field fundus autofluorescence corresponds to visual fields in chorioretinitis patients. (22174575)
2011
7
A case of chorioretinal coloboma in a patient with achondroplasia. (21052511)
2010
8
A presentation of longstanding toxoplasmosis chorioretinitis. (19111254)
2009
9
Posterior placoid chorioretinitis: An unusual ocular manifestation of syphilis. (19668773)
2008
10
Chorioretinal dysplasia, hydranencephaly, and intracranial calcifications: pseudo-TORCH or a new syndrome? (18084237)
2008
11
Toxoplasmic chorioretinitis and antitumor necrosis factor treatment in rheumatoid arthritis. (17067660)
2007
12
Chorioretinitis with late pigmentary changes in a carrier of human T-lymphotropic virus 1. (17923563)
2007
13
Acute syphilitic posterior placoid chorioretinitis after an intravitreal triamcinolone acetonide injection. (16704715)
2006
14
Pigmented paravenous chorioretinal atrophy is associated with a mutation within the crumbs homolog 1 (CRB1) gene. (15623792)
2005
15
HLA-B27-associated uveitis with a chorioretinitis manifestation. (15792320)
2005
16
Clinical and electrophysiological course of acute syphilitic posterior placoid chorioretinitis. (15785996)
2005
17
Extensive chorioretinitis and severe vision loss associated with west nile virus meningoencephalitis. (16344453)
2005
18
Vitritis and chorioretinitis in a patient with West Nile virus infection. (12583786)
2003
19
West Nile virus chorioretinitis. (12652240)
2003
20
Fluorescein and indocyanine green angiographic features in acute syphilitic macular placoid chorioretinitis. (12956283)
2003
21
Chorioretinitis sclopetaria from BB ex memoria. (11300639)
2001
22
Microcephaly with chorioretinal dysplasia: characteristic facial features. (11146476)
2000
23
Microcephaly-lymphedema-chorioretinal dysplasia: a unique genetic syndrome with variable expression and possible characteristic facial appearance. (10482868)
1999
24
Chorioretinal coloboma with hypoplasia of the inferior rectus muscle in a microphthalmic eye. (9503320)
1998
25
Ophthalmoscopic visualization of the inferior ophthalmic vein through a chorioretinal coloboma. (7832239)
1995
26
Neurophysiological correlates in a case of unilateral iris and chorioretinal coloboma. (2760396)
1989
27
Retinal striae as a sign of resolving candidal chorioretinitis. (3209087)
1988
28
Disseminated coccidioidomycosis with chorioretinitis in early infancy. (3952015)
1986
29
Juxtapapillary chorioretinitis in neurosyphilis. A case report. (6464683)
1984
30
Nectrotizing chorioretinitis induced by herpes simplex virus infection in the neonate. (6656623)
1983
31
Pigmented paravenous chorioretinal atrophy. (6614113)
1983
32
Acute macular chorioretinitis associated with scorpion sting: a case report. (622733)
1978
33
Acquired CMV chorioretinitis in severe combined immunodeficiency. (200385)
1978
34
Toxoplasmic chorioretinitis affecting the macula. (577367)
1977
35
Chorioretinitis sclopetaria: choroidal and retinal concussion injury from a bullet. (836216)
1977
36
Experimental chorioretinitis in rabbits following injection of autologous retina in Freund's complete adjuvant. (976381)
1976
37
Neonatal cytomegalic inclusion disease chorioretinitis. (4342440)
1972
38
Amphotericin B therapy in the treatment of presumed histoplasma chorioretinitis. A further appraisal. (4298169)
1968
39
Chorioretinitis: its etiology and therapy. (5674133)
1968
40
Acquired toxoplasmic chorioretinitis. (6040929)
1967
41
Experimental Candida albicans chorioretinitis treated by laser. (6019529)
1967
42
THE ETIOLOGICAL AGENT OF SEROUS CENTRAL CHORIORETINITIS. (14218712)
1964
43
Toxoplasmic versus amebic chorioretinitis. Report of a case with a study of the intraocular fluid antibody levels. (13991398)
1963
44
CHORIORETINITIS AND HYDROCEPHALUS. (14043561)
1963
45
A study of the role of toxoplasmosis in adult chorioretinitis. (13124437)
1954
46
Toxoplasma-like protozoa in chorioretinitis in adults. (13040676)
1953
47
Nematode chorioretinitis; report of a case, with photographs of a viable worm. (14923038)
1952
48
Primary chorioretinal aberrations with night blindness; discussion. (15443030)
1950
49
Primary chorioretinal aberrations with night blindness; pathology. (15443028)
1950
50
A syndrome characterized by generalized cutaneous eruption, chorioretinitis and eosinophilia, probably due to chronic toxoplasma infection. (18139423)
1949

Genetic Variations for Chorioretinitis

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Expression for genes affiliated with Chorioretinitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Chorioretinitis

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Pathways for genes affiliated with Chorioretinitis

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37NCBI BioSystems Database, 53Reactome, 51QIAGEN
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Pathways related to Chorioretinitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.2RBP3, RPE65
2
Hide members
10.0RBP3, SAG, RPE65
310.0RBP3, SAG, RPE65

Compounds for genes affiliated with Chorioretinitis

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44Novoseek, 24HMDB
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Compounds related to Chorioretinitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
111-cis-retinol44 2410.9RBP3, RPE65
2copper44 2410.8MT3, MT2A, AOC2

GO Terms for genes affiliated with Chorioretinitis

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16Gene Ontology
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Biological processes related to Chorioretinitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1phototransduction, visible lightGO:00760310.0RBP3, SAG, RPE65
2visual perceptionGO:0076018.6OAT, RPE65, SAG, RBP3, AOC2, PRPH2

Products for genes affiliated with Chorioretinitis

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Sources for Chorioretinitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet