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MCID: CHR078
MIFTS: 41

Chorioretinitis

Categories: Rare diseases, Eye diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Chorioretinitis

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MalaCards integrated aliases for Chorioretinitis:

Name: Chorioretinitis 12 72 49 51 41 14 69
Retinochoroiditis 12

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:8886
ICD10 32 H30 H30.9
ICD9CM 34 363.20
MeSH 41 D002825
NCIt 46 C110923
UMLS 69 C0008513
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Summaries for Chorioretinitis

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MalaCards based summary : Chorioretinitis, also known as retinochoroiditis, is related to focal chorioretinitis and congenital toxoplasmosis, and has symptoms including eye manifestations An important gene associated with Chorioretinitis is RBP3 (Retinol Binding Protein 3), and among its related pathways/superpathways are Primary immunodeficiency and A-beta Pathways: Uptake and Degradation. The drugs Dexamethasone and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and liver.

Wikipedia : 72 Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina... more...

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Related Diseases for Chorioretinitis

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Diseases related to Chorioretinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 361)
# Related Disease Score Top Affiliating Genes
1 focal chorioretinitis 33.9 CD40LG SAG
2 congenital toxoplasmosis 32.3 CD40LG CD79A
3 posterior uveitis 30.2 RBP3 SAG
4 neuroretinitis 30.0 CD40LG EXTL3
5 iridocyclitis 30.0 CD40LG MRAP
6 eales disease 29.9 RBP3 SAG
7 chickenpox 29.9 CD40LG CD79A
8 vasculitis 29.8 CD40LG CD79A CX3CL1
9 ocular toxoplasmosis 29.7 CD40LG CD79A
10 syphilis 29.6 CD40LG CD79A EXTL3
11 panuveitis 29.6 CD40LG MRAP RBP3 SAG
12 meningoencephalitis 29.5 CD40LG CD79A
13 primary syphilis 29.4 CD40LG EXTL3
14 latent syphilis 29.4 CD40LG EXTL3
15 spondyloarthropathy 1 29.3 CD40LG CD79A MRAP
16 secondary syphilis 29.2 CD40LG CD79A EXTL3
17 congenital syphilis 28.9 CD40LG CD79A EXTL3
18 retinochoroidal coloboma 12.4
19 sveinsson chorioretinal atrophy 12.3
20 pigmented paravenous chorioretinal atrophy 12.3
21 chorioretinal atrophy, progressive bifocal 12.3
22 microcornea, myopic chorioretinal atrophy, and telecanthus 12.3
23 chorioretinal scar 12.1
24 aicardi syndrome 12.1
25 disseminated chorioretinitis 12.0
26 boucher-neuhauser syndrome 11.9
27 peripheral focal chorioretinitis 11.9
28 cleft lower lip cleft lateral canthi chorioretinal 11.8
29 ataxia - hypogonadism - choroidal dystrophy 11.8
30 birdshot chorioretinopathy 11.6
31 choroiditis 11.4
32 gyrate atrophy of choroid and retina 11.4
33 microcephaly with or without chorioretinopathy, lymphedema, or mental retardation 11.3
34 choroideremia 11.2
35 wagner vitreoretinopathy 11.1
36 oliver-mcfarlane syndrome 11.0
37 vitreoretinochoroidopathy dominant 11.0
38 arima syndrome 11.0
39 microcephaly and chorioretinopathy, autosomal recessive, 1 11.0
40 joubert syndrome with oculorenal anomalies 11.0
41 noble bass sherman syndrome 11.0
42 cone-rod dystrophy 2 10.9
43 aicardi-goutieres syndrome 1 10.9
44 late-onset retinal degeneration 10.9
45 microcephaly and chorioretinopathy, autosomal recessive, 3 10.9
46 retinitis 10.8
47 peripapillary atrophy, beta type 10.8
48 maumenee syndrome 10.8
49 stickler syndrome, type i 10.8
50 optic disc anomalies with retinal and/or macular dystrophy 10.8

Graphical network of the top 20 diseases related to Chorioretinitis:



Diseases related to Chorioretinitis
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Symptoms & Phenotypes for Chorioretinitis

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UMLS symptoms related to Chorioretinitis:


eye manifestations
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Drugs & Therapeutics for Chorioretinitis

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Drugs for Chorioretinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 62)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
2
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
3
Sulfadiazine Approved, Investigational, Vet_approved Phase 3 68-35-9 5215
4
Pyrimethamine Approved, Investigational, Vet_approved Phase 3 58-14-0 4993
5
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
6
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
7
Sulfamethoxazole Approved Phase 3 723-46-6 5329
8
Trimethoprim Approved, Vet_approved Phase 3 738-70-5 5578
9
leucovorin Approved, Nutraceutical Phase 3 58-05-9 143 6006
10
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
11 Prednisolone acetate Phase 3
12 Dexamethasone acetate Phase 3 1177-87-3
13 glucocorticoids Phase 3,Phase 2
14
protease inhibitors Phase 3
15 Methylprednisolone acetate Phase 3
16 Methylprednisolone Hemisuccinate Phase 3
17 Folic Acid Antagonists Phase 3
18 Gastrointestinal Agents Phase 3
19 Neuroprotective Agents Phase 3
20 Clindamycin palmitate Phase 3
21 Clindamycin phosphate Phase 3
22 HIV Protease Inhibitors Phase 3
23 Hormone Antagonists Phase 3,Phase 1,Phase 2
24 Vitamin B Complex Phase 3
25 Hormones Phase 3,Phase 1,Phase 2
26 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 1,Phase 2
27 Peripheral Nervous System Agents Phase 3
28 Anti-Bacterial Agents Phase 3
29 Antiemetics Phase 3
30 Anti-Infective Agents Phase 3,Phase 2
31 Antimalarials Phase 3
32 Prednisolone hemisuccinate Phase 3
33 Prednisolone phosphate Phase 3
34 Anti-Inflammatory Agents Phase 3,Phase 2
35 Protective Agents Phase 3
36 Antineoplastic Agents, Hormonal Phase 3,Phase 2
37 Antiprotozoal Agents Phase 3
38 BB 1101 Phase 3
39 Antiparasitic Agents Phase 3
40 Autonomic Agents Phase 3
41 Renal Agents Phase 3
42 Trimethoprim, Sulfamethoxazole Drug Combination Phase 3
43 Cytochrome P-450 Enzyme Inhibitors Phase 3
44 Rho(D) Immune Globulin Phase 3
45 gamma-Globulins Phase 3
46 Immunoglobulins Phase 3
47 Immunoglobulins, Intravenous Phase 3
48 Antibodies Phase 3
49 Folate Nutraceutical Phase 3
50 Vitamin B9 Nutraceutical Phase 3

Interventional clinical trials:

(show all 11)

# Name Status NCT ID Phase Drugs
1 To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis Unknown status NCT00372294 Phase 3 pyrimethamine-sulfadiazine + prednisolone;Clindamycin+Dexamethasone
2 Assessment of Two Therapeutic Strategies in the Treatment of Children With Congenital Toxoplasmosis Unknown status NCT01202500 Phase 3
3 Influence of Trimethoprim-Sulfamethoxazole for the Recurrence of Ocular Toxoplasmosis Completed NCT01449877 Phase 3 Trimethoprim-Sulfamethoxazole
4 A Randomized Trial to Prevent Congenital Cytomegalovirus (CMV) Recruiting NCT01376778 Phase 3 CMV hyperimmune globulin
5 Effect of Spironolactone in Treating Chronic Non-resolutive Central Serous Chorioretinitis Completed NCT01552044 Phase 1, Phase 2 Spironolactone;Placebo
6 Evaluation of Birdshot Retine Choroidopathy Treatment by Either Steroid or Interferon alpha2a Completed NCT00508040 Phase 2 interferon alpha 2a;prednisone
7 Safety and Efficacy of AIN457 in Noninfectious Uveitis Completed NCT00685399 Phase 2 AIN457;AIN 457;AIN457
8 Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis Completed NCT02843438 Anti-toxoplasmosis treatment;Anti-inflammatory treatments
9 Study of the Choroidal Thickness Variations After Ingestion of RedBull® Energy Drink Completed NCT02856256
10 Relevance of Gastric Aspirate in HCMV Detection Recruiting NCT03262194
11 Postnatal HCMV Infection in Very Preterm Infants. Implications, Morbidity, Growth and Neurodevelopmental Outcomes. Withdrawn NCT01151462

Search NIH Clinical Center for Chorioretinitis

Cochrane evidence based reviews: chorioretinitis

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Genetic Tests for Chorioretinitis

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Anatomical Context for Chorioretinitis

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MalaCards organs/tissues related to Chorioretinitis:

38
Retina, Eye, Liver, Testes, B Cells, Spinal Cord, Brain
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Publications for Chorioretinitis

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Articles related to Chorioretinitis:

(show top 50) (show all 518)
# Title Authors Year
1
Chorioretinal Punched-Out Lesions in Pseudoxanthoma Elasticum. ( 29370032 )
2018
2
Varicella zoster virus-associated Chorioretinitis: a case report. ( 29402251 )
2018
3
PIGMENTED PARAVENOUS CHORIORETINAL ATROPHY-DETAILED CLINICAL STUDY OF A LARGE COHORT. ( 29300249 )
2018
4
SOLITARY RETINAL CAPILLARY HEMANGIOMA IN A PATIENT WITH BILATERAL CHORIORETINAL COLOBOMA. ( 28358746 )
2017
5
Rapid resolution of toxoplasma chorioretinitis treatment using quadruple therapy. ( 29238162 )
2017
6
Birdshot Chorioretinitis and Fundus Autofluorescence: Novel Insights Into Disease Pathogenesis. ( 28800649 )
2017
7
Stroke Due to Cerebral Vasculitis in a Patient with Relentless Placoid Chorioretinitis. ( 28282738 )
2017
8
GOOD VISUAL OUTCOME IN A BILATERAL MULTIFOCAL SYPHILITIC CHORIORETINITIS, DESPITE LATE DIAGNOSIS. ( 28125501 )
2017
9
CLINICAL PATHOLOGIC CORRELATION OF SARCOIDOSIS-ASSOCIATED MULTIFOCAL CHORIORETINITIS IN AN ELDERLY PATIENT. ( 28145942 )
2017
10
Use of Smartphone Funduscopy to aid Diagnosis of chorioretinitis after donor-recipient mismatched cardiac transplantation. ( 28951505 )
2017
11
Fungal chorioretinitis with systemic candidiasis in an infant following treatment with broad spectrum antibiotics: A case report. ( 28672927 )
2017
12
RELENTLESS PLACOID CHORIORETINITIS: SUCCESSFUL LONG-TERM TREATMENT WITH INTRAVITREAL TRIAMCINOLONE. ( 28198750 )
2017
13
Chorioretinitis: a potential clue to the early diagnosis of subacute sclerosing panencephalitis. ( 28512208 )
2017
14
Intravitreal aflibercept for choroidal neovascularization associated with chorioretinitis: a pilot study. ( 28769551 )
2017
15
Erratum: Intravitreal aflibercept for choroidal neovascularization associated with chorioretinitis: a pilot study [Corrigendum]. ( 28894355 )
2017
16
SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY EVALUATION OF CHORIORETINAL CHANGES IN HYPERTENSIVE CHOROIDOPATHY RELATED TO HELLP SYNDROME. ( 28067720 )
2017
17
Infectious chorioretinitis in an immunocompetent patient: A diagnostic dilemma. ( 29044084 )
2017
18
Sveinsson Chorioretinal Atrophy: Helicoid Peripapillary Chorioretinal Degeneration. ( 29049677 )
2017
19
Application of OCT-angiography to characterise the evolution of chorioretinal lesions in acute posterior multifocal placoid pigment epitheliopathy. ( 28983094 )
2017
20
MULTIMODAL IMAGING ADDS NEW INSIGHTS INTO ACUTE SYPHILITIC POSTERIOR PLACOID CHORIORETINITIS. ( 29023263 )
2017
21
Chronic Central Serous Chorioretinopathy-Like Maculopathy as Atypical Presentation of Chorioretinal Folds. ( 29422860 )
2017
22
VITREOUS TREPONEMAL ANTIBODY AS A SUPPLEMENTARY TEST TO SEROLOGY FOR THE CONFIRMATION OF SYPHILITIC CHORIORETINITIS. ( 29176538 )
2017
23
A Novel clinical sign in Intraocular Tuberculosis: Active chorioretinitis within chorioretinal atrophy. ( 29152599 )
2017
24
Bevacizumab for treatment of choroidal neovascularization secondary to candida chorioretinitis. ( 28361379 )
2017
25
SURGICAL OUTCOMES AND COMPLICATIONS OF RHEGMATOGENOUS RETINAL DETACHMENT IN EYES WITH CHORIORETINAL COLOBOMA: The Results of the KKESH International Collaborative Retina Study Group. ( 28067725 )
2017
26
Fundus Autofluorescence Findings in Eyes With Birdshot Chorioretinitis. ( 28800648 )
2017
27
Toxoplasmosis with chorioretinitis in an HIV-infected child with no visual complaints-importance of fundus examination. ( 28058107 )
2017
28
Chorioretinal Perfusion in Persistent Placoid Maculopathy. ( 29253308 )
2017
29
Optical Coherence Tomography Findings in Endogenous Fungal Chorioretinitis, Retinitis, and Endophthalmitis. ( 29121358 )
2017
30
Contribution of Dual Fluorescein and Indocyanine Green Angiography to the Appraisal of Presumed Tuberculous Chorioretinitis in a Non-endemic Area. ( 28299004 )
2017
31
SPONTANEOUS IMPROVEMENT OF SYPHILIS CHORIORETINITIS: CASE REPORT AND REVIEW OF THE LITERATURE. ( 29176535 )
2017
32
Swept-Source Optical Coherence Tomography Angiography in West Nile Virus Chorioretinitis and Associated Occlusive Retinal Vasculitis. ( 28810044 )
2017
33
En Face: Disappearing Outer Retinal Dots in Treated Syphilitic Chorioretinitis. ( 26902563 )
2016
34
Syphilitic placoid chorioretinitis. A case-report. ( 26920946 )
2016
35
Sequential Chorioretinal Changes in Presumed Ocular Histoplasmosis Syndrome Analyzed Using Spectral Domain Optical Coherence Tomography. ( 27082105 )
2016
36
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF CHORIORETINAL LESIONS DUE TO IDIOPATHIC MULTIFOCAL CHOROIDITIS. ( 27880741 )
2016
37
Histiocytic chorioretinitis in a dog. ( 27520710 )
2016
38
Bilateral Chorioretinitis as Syphilis Presentation: Multimodal Characterization and Therapy Response. ( 27790481 )
2016
39
CHORIORETINAL WHITE DOT LESIONS IN EYES WITH MULTIFOCAL CHOROIDITIS AND TILTED DISK SYNDROME WITH INFERIOR STAPHYLOMA. ( 27380431 )
2016
40
Toxoplasma chorioretinitis following renal transplantation. ( 26880467 )
2016
41
Sleep Mask-like Chorioretinal Atrophy in a Patient With Alagille Syndrome. ( 27858950 )
2016
42
Effects of PUFAs in a Mouse Model of HSV-1 Chorioretinitis. ( 27438625 )
2016
43
Post-prophylaxis Toxoplasma chorioretinitis following donor-recipient mismatched liver transplantation. ( 27500398 )
2016
44
Cataract, strabismus and chorioretinal coloboma in paediatric HIV infection. ( 27956343 )
2016
45
BIRDSHOT CHORIORETINITIS LESIONS ON INDOCYANINE GREEN ANGIOGRAPHY AS AN INDICATOR OF DISEASE ACTIVITY. ( 26977742 )
2016
46
TECHNIQUE OF LASER CHORIORETINAL ANASTOMOSIS CREATION IN CENTRAL RETINAL VEIN OCCLUSION AND SUCCESS RATE WITH A NEW PHOTOCOAGULATOR SYSTEM. ( 26991650 )
2016
47
Bilateral optic nerve head drusen with chorioretinal coloboma in the right eye. ( 27099847 )
2016
48
Choroidal Findings in Eyes With Birdshot Chorioretinitis Using Enhanced-Depth Optical Coherence Tomography. ( 27599125 )
2016
49
Secondary Syphilis Presenting as Oral Lesions and Posterior Placoid Chorioretinitis in an Immunocompetent Patient. ( 27340116 )
2016
50
Syphilitic posterior placoid chorioretinitis as initial presentation of early neurosyphilis. ( 27956326 )
2016
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Variations for Chorioretinitis

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Expression for Chorioretinitis

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Search GEO for disease gene expression data for Chorioretinitis.
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Pathways for Chorioretinitis

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Pathways related to Chorioretinitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Primary immunodeficiency 36
10.52 CD40LG CD79A
2
A-beta Pathways: Uptake and Degradation 61
10.13 CD40LG CX3CL1
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GO Terms for Chorioretinitis

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Biological processes related to Chorioretinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell proliferation GO:0042100 8.62 CD40LG CD79A
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Sources for Chorioretinitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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