MCID: CHR080
MIFTS: 27

Choroidal Sclerosis malady

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Choroidal Sclerosis

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Aliases & Descriptions for Choroidal Sclerosis:

Name: Choroidal Sclerosis 11 13 25 37 66
 
Choroidal Degenerations 11

Classifications:



External Ids:

Disease Ontology11 DOID:980
ICD1028 H31.1, H31.10
ICD9CM30 363.4, 363.40
MeSH37 C535358

Summaries for Choroidal Sclerosis

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MalaCards based summary: Choroidal Sclerosis, also known as choroidal degenerations, is related to localized scleroderma and choroideremia. An important gene associated with Choroidal Sclerosis is CYP4V2 (Cytochrome P450 Family 4 Subfamily V Member 2), and among its related pathways are Phototransduction and Visual Cycle in Retinal Rods. Affiliated tissues include eye, and related mouse phenotype vision/eye.

Related Diseases for Choroidal Sclerosis

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Graphical network of the top 20 diseases related to Choroidal Sclerosis:



Diseases related to choroidal sclerosis

Symptoms for Choroidal Sclerosis

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Drugs & Therapeutics for Choroidal Sclerosis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Choroidal Sclerosis


Cochrane evidence based reviews: choroidal sclerosis

Genetic Tests for Choroidal Sclerosis

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Genetic tests related to Choroidal Sclerosis:

id Genetic test Affiliating Genes
1 Choroidal Sclerosis25

Anatomical Context for Choroidal Sclerosis

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MalaCards organs/tissues related to Choroidal Sclerosis:

34
Eye

Animal Models for Choroidal Sclerosis or affiliated genes

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MGI Mouse Phenotypes related to Choroidal Sclerosis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.4GUCA1A, GUCA1B, GUCY2D, PRPH2

Publications for Choroidal Sclerosis

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Articles related to Choroidal Sclerosis:

(show all 17)
idTitleAuthorsYear
1
Fundus autofluorescence, optical coherence tomography, and electroretinogram findings in choroidal sclerosis. (20224472)
2010
2
Choroidal sclerosis in localized scleroderma (morphea en plaque). (18223304)
2008
3
Annular choroidal sclerosis. (952825)
1976
4
Degenerative choroidal sclerosis with a peculiar bilateral pattern. (1147496)
1975
5
X-linked choroidal sclerosis. A stage of choroideremia. (4827609)
1974
6
Senile choroidal sclerosis. (4694397)
1973
7
Fluorescein studies of choroidal sclerosis. (5100469)
1971
8
Circinate choroidal sclerosis. (5425205)
1970
9
Fluorescein photography in choroidal sclerosis. (5764681)
1969
10
CENTRAL CHOROIDAL SCLEROSIS. A CLINICAL AND PATHOLOGIC STUDY. (14195983)
1964
11
Choroidal sclerosis; a possible intermediate sex-linked form. (13293325)
1956
12
Generalized choroidal sclerosis; course and mode of inheritance. (14378508)
1955
13
Central areolar choroidal sclerosis; a histo-pathological study. (13032370)
1953
14
Central areolar choroidal sclerosis. (13032369)
1953
15
Familial Central and Peripapillary Choroidal Sclerosis Associated with Familial Pseudoxanthoma Elasticum. (16693479)
1948
16
Choroidal Sclerosis: (Section of Ophthalmology). (19990208)
1935
17
Choroidal Sclerosis. (19985446)
1926

Variations for Choroidal Sclerosis

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Expression for genes affiliated with Choroidal Sclerosis

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Search GEO for disease gene expression data for Choroidal Sclerosis.

Pathways for genes affiliated with Choroidal Sclerosis

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GO Terms for genes affiliated with Choroidal Sclerosis

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Cellular components related to Choroidal Sclerosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1photoreceptor inner segmentGO:00019179.3GUCA1A, GUCA1B
2photoreceptor disc membraneGO:00973819.1GUCA1A, GUCA1B, GUCY2D

Biological processes related to Choroidal Sclerosis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1receptor guanylyl cyclase signaling pathwayGO:000716810.0GUCA1B, GUCY2D
2regulation of guanylate cyclase activityGO:00312829.9GUCA1A, GUCA1B
3positive regulation of guanylate cyclase activityGO:00312849.9GUCA1A, GUCA1B
4phototransductionGO:00076029.7GUCA1A, GUCA1B
5response to stimulusGO:00508969.4CYP4V2, RIMS1
6regulation of rhodopsin mediated signaling pathwayGO:00224009.2GUCA1A, GUCA1B, GUCY2D
7visual perceptionGO:00076017.1CYP4V2, GUCA1A, GUCA1B, GUCY2D, PRPH2, RIMS1

Molecular functions related to Choroidal Sclerosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1guanylate cyclase regulator activityGO:00302499.4GUCA1A, GUCA1B
2calcium sensitive guanylate cyclase activator activityGO:00080489.3GUCA1A, GUCA1B

Sources for Choroidal Sclerosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet