MCID: CHR008
MIFTS: 44

Choroiditis malady

Categories: Rare diseases, Eye diseases

Aliases & Classifications for Choroiditis

Aliases & Descriptions for Choroiditis:

Name: Choroiditis 12 50 42 14 69

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology 12 DOID:11406
ICD10 33 H30.9
MeSH 42 D002833
NCIt 47 C35111
SNOMED-CT 64 16553002 193449000
UMLS 69 C0008526

Summaries for Choroiditis

MalaCards based summary : Choroiditis is related to tuberculosis and hepatitis. An important gene associated with Choroiditis is CFH (Complement Factor H), and among its related pathways/superpathways are Innate Lymphoid Cell Differentiation Pathways and Dendritic Cells Developmental Lineage Pathway. The drugs Dexamethasone and Bevacizumab have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and endothelial.

Wikipedia : 71 Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina... more...

Related Diseases for Choroiditis

Diseases related to Choroiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 775)
id Related Disease Score Top Affiliating Genes
1 tuberculosis 29.8 IL10 TNF
2 hepatitis 29.5 IL10 TNF
3 cryptococcosis 29.2 IL10 TNF
4 astrocytoma 29.2 IL10 TNF
5 central nervous system lymphoma 28.9 IL10 TNF
6 chordoid meningioma 28.9 IL10 TNF
7 colon adenocarcinoma 28.8 IL10 TNF
8 choroid plexus papilloma 12.4
9 choroid disease 12.2
10 serpiginous choroiditis 12.2
11 gyrate atrophy of choroid and retina with or without ornithinemia 12.2
12 choroid plexus cancer 12.2
13 multifocal choroiditis 12.1
14 choroid plexus cyst 12.1
15 choroidal sclerosis 12.0
16 partial central choroid dystrophy 12.0
17 choroid spindle cell melanoma 12.0
18 atypical choroid plexus papilloma 11.9
19 malignant choroid melanoma 11.9
20 choroid plexus meningioma 11.9
21 hereditary choroidal atrophy 11.9
22 choroideremia 11.8
23 birdshot chorioretinopathy 11.7
24 choroid mixed cell melanoma 11.7
25 adult choroid plexus cancer 11.7
26 ataxia - hypogonadism - choroidal dystrophy 11.7
27 choroid epithelioid cell melanoma 11.7
28 childhood choroid plexus cancer 11.7
29 choroid necrotic melanoma 11.7
30 partial circumpapillary choroid dystrophy 11.7
31 central gyrate choroidal dystrophy 11.7
32 total circumpapillary dystrophy of choroid 11.7
33 choroid plexus calcification and mental retardation 11.7
34 uveal melanoma 11.6
35 senile atrophy of choroid 11.6
36 thumb, hypoplastic, with choroid coloboma, poorly developed antihelix, and deafness 11.6
37 angioid streaks of choroid 11.6
38 diffuse secondary choroid atrophy 11.6
39 retinochoroidal coloboma 11.6
40 choriodal dystrophy, central areolar 2 11.5
41 chorioretinitis 11.4
42 coloboma, ocular 11.3
43 macular dystrophy, vitelliform, 3 11.3
44 central serous chorioretinopathy 11.2
45 ocular melanoma 11.2
46 punctate inner choroidopathy 11.1
47 pars planitis 11.1
48 posterior uveal melanoma 11.1
49 pseudoxanthoma elasticum 11.1
50 li-fraumeni syndrome 11.1

Graphical network of the top 20 diseases related to Choroiditis:



Diseases related to Choroiditis

Symptoms & Phenotypes for Choroiditis

Drugs & Therapeutics for Choroiditis

Drugs for Choroiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 78)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-02-2 5743
2
Bevacizumab Approved, Investigational Phase 4,Phase 3 216974-75-3
3 Dexamethasone acetate Phase 4,Phase 3,Phase 2 1177-87-3
4 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
5
protease inhibitors Phase 4,Phase 3,Phase 2
6 Gastrointestinal Agents Phase 4,Phase 3,Phase 2
7 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2
8 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
9 Dexamethasone 21-phosphate Phase 4,Phase 3,Phase 2
10 Hormones Phase 4,Phase 3,Phase 2,Phase 1
11 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
12 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
13 Immunosuppressive Agents Phase 4,Phase 3,Phase 1,Phase 2
14 Antiemetics Phase 4,Phase 3,Phase 2
15 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
16 BB 1101 Phase 4,Phase 3,Phase 2
17 Autonomic Agents Phase 4,Phase 3,Phase 2
18 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2
19 beta-endorphin Phase 4
20 Adrenocorticotropic Hormone Phase 4
21 Angiogenesis Inhibitors Phase 4,Phase 3,Phase 1,Phase 2
22 Angiogenesis Modulating Agents Phase 4,Phase 3,Phase 1,Phase 2
23 Melanocyte-Stimulating Hormones Phase 4
24
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
25
Sulfadiazine Approved, Vet_approved Phase 3 68-35-9 5215
26
Pyrimethamine Approved, Vet_approved Phase 3 58-14-0 4993
27
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
28
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
29
Methotrexate Approved Phase 3,Phase 1,Phase 2 1959-05-2, 59-05-2 126941
30
Mycophenolic acid Approved Phase 3 24280-93-1 446541
31
Mycophenolate mofetil Approved, Investigational Phase 3 128794-94-5 5281078
32
Triamcinolone Approved, Vet_approved Phase 3,Phase 1,Phase 2 124-94-7 31307
33
Fluocinolone Acetonide Approved, Investigational, Vet_approved Phase 3 67-73-2 6215
34
Prednisone Approved, Vet_approved Phase 3,Phase 2 53-03-2 5865
35
leucovorin Approved, Nutraceutical Phase 3,Phase 1,Phase 2 58-05-9 54575, 6560146 143
36
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 1,Phase 2 59-30-3 6037
37 Prednisolone acetate Phase 3
38 Folic Acid Antagonists Phase 3,Phase 1,Phase 2
39 Clindamycin palmitate Phase 3
40 Clindamycin phosphate Phase 3
41 Neuroprotective Agents Phase 3
42 Vitamin B Complex Phase 3,Phase 1,Phase 2
43 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
44 Prednisolone hemisuccinate Phase 3
45 Prednisolone phosphate Phase 3
46 Anti-Infective Agents Phase 3,Phase 2,Phase 1
47 Protective Agents Phase 3
48 Antimalarials Phase 3
49 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
50 Methylprednisolone acetate Phase 3

Interventional clinical trials:

(show all 35)
id Name Status NCT ID Phase
1 Intravitreal Bevacizumab in Recalcitrant Inflammatory Ocular Neovascularization Completed NCT00645697 Phase 4
2 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients Completed NCT02764697 Phase 4
3 Study of the Effectiveness of Ozurdex for the Control of Uveitis Recruiting NCT02049476 Phase 4
4 To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis Unknown status NCT00372294 Phase 3
5 Intravitreal Bevacizumab for Inflammatory Neovascular Membranes Completed NCT00407121 Phase 3
6 A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis Completed NCT00404742 Phase 3
7 A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis Completed NCT00404612 Phase 3
8 A Study of the Safety and Efficacy of a New Treatment for Non-Infectious Intermediate or Posterior Uveitis Completed NCT00333814 Phase 2, Phase 3
9 Myfortic for the Treatment of Non-infectious Intermediate Uveitis Completed NCT01092533 Phase 3
10 Randomized, Controlled Trial to Test the Efficacy of Interferon Beta in the Treatment of Intermediate Uveitis Completed NCT00344253 Phase 3
11 Suprachoroidal Injection of CLS-TA in Subjects Non-infectious Uveitis Recruiting NCT03097315 Phase 3
12 Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis Recruiting NCT02595398 Phase 3
13 A Controlled, Multi-center Study of the Utilization and Safety of the MK II Inserter and the Safety of the FAI Insert in Subjects With Non-infectious Uveitis Affecting the Posterior Segment of the Eye Active, not recruiting NCT02748512 Phase 3
14 Safety and Efficacy Study of a Fluocinolone Acetonide Intravitreal (FAI) Insert in Subjects With Chronic Non-infectious Posterior Uveitis Active, not recruiting NCT02746991 Phase 3
15 Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert Active, not recruiting NCT01694186 Phase 3
16 Treatment of Exudative and Vasogenic Chorioretinal Diseases Including Variants of AMD and Other CNV Related Maculopathy Completed NCT00470977 Phase 1, Phase 2
17 Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis Completed NCT01789320 Phase 1, Phase 2
18 Safety and Efficacy of AIN457 in Noninfectious Uveitis Completed NCT00685399 Phase 2
19 Effect of Spironolactone in Treating Chronic Non-resolutive Central Serous Chorioretinitis Completed NCT01552044 Phase 1, Phase 2
20 Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis Completed NCT02255032 Phase 2
21 Evaluation of Birdshot Retine Choroidopathy Treatment by Either Steroid or Interferon alpha2a Completed NCT00508040 Phase 2
22 Safety,Tolerability and Efficacy of Intravitreal LFG316 in Patients With Active Non-infectious Intermediate-, posterior-or Panuveitis , Recruiting NCT01526889 Phase 2
23 Intravitreal Sirolimus as Therapeutic Approach to Uveitis Recruiting NCT01280669 Phase 2
24 Study of the Safety, Tolerability, and Bioactivity of Tocilizumab On Patients With Non-infectious UVEITIS: The STOP-UVEITIS Study Active, not recruiting NCT01717170 Phase 1, Phase 2
25 Safety &Efficacy of CF101 to Subjects With Uveitis Not yet recruiting NCT01905124 Phase 2
26 Safety and Preliminary Efficacy Study of V404 PDS in Uveitis Terminated NCT02125266 Phase 1, Phase 2
27 Sirolimus as Therapeutic Approach to Uveitis Unknown status NCT00908466 Phase 1
28 Evaluation and Treatment of Patients With Inflammatory Eye Diseases Completed NCT00006188
29 Retisert and Cataract Surgery in Patients With Severe Uveitis Completed NCT00570830
30 Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis Completed NCT02843438
31 Quality of Life in Patients With Intermediate Uveitis Completed NCT01314469
32 Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301 Recruiting NCT02952001
33 Variations in Retinal Nerve Fiber Layer Thickness During Uncomplicated Anterior and Intermediate Uveitis Not yet recruiting NCT02879084
34 Intravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMD Withdrawn NCT01256580
35 Postnatal HCMV Infection in Very Preterm Infants. Implications, Morbidity, Growth and Neurodevelopmental Outcomes. Withdrawn NCT01151462

Search NIH Clinical Center for Choroiditis

Cochrane evidence based reviews: choroiditis

Genetic Tests for Choroiditis

Anatomical Context for Choroiditis

MalaCards organs/tissues related to Choroiditis:

39
Retina, Eye, Endothelial, Brain, Lung, Thyroid, Bone

Publications for Choroiditis

Articles related to Choroiditis:

(show top 50) (show all 2611)
id Title Authors Year
1
Ranibizumab for choroidal neovascularization secondary to pseudoxanthoma elasticum: 4-year results from the PIXEL study in France. ( 28493086 )
2017
2
Subfoveal Choroidal Thickness in Central Serous Chorioretinopathy: A Meta-Analysis. ( 28076442 )
2017
3
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY SHOWS INNER CHOROIDAL ISCHEMIA IN ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY. ( 27759710 )
2017
4
Long-term follow-up of patients with choroidal neovascularization due to angioid streaks. ( 28031699 )
2017
5
CHOROIDAL THICKNESS IN PATIENTS WITH STARGARDT DISEASE. ( 28198784 )
2017
6
Choroidal Imaging with Swept-Source Optical Coherence Tomography in Patients with Birdshot Chorioretinopathy: Choroidal Reflectivity and Thickness. ( 28456419 )
2017
7
A rare case of choroid plexus carcinoma that led to the diagnosis of Lynch syndrome (hereditary nonpolyposis colorectal cancer). ( 28460341 )
2017
8
Bilateral choroidal neovascularisation associated with adult-onset foveomacular vitelliform dystrophy. ( 27558081 )
2017
9
Ultrasonic elastography exploration of the foetal brain: A case of atypical choroid plexus papilloma. ( 28421905 )
2017
10
Increased Choroidal Vascularity in Central Serous Chorioretinopathy Quantified Using Swept-Source Optical Coherence Tomography. ( 27894511 )
2017
11
Choroid plexus papilloma. ( 28413558 )
2017
12
Treatment of choice for patients with EGFR mutation-positive non-small cell lung carcinoma presenting with choroidal metastases: radiotherapy or TKIs? ( 28237165 )
2017
13
Choroid plexus involvement in Rosai-Dorfman disease. ( 28084291 )
2017
14
Evaluation of macular and peripapillary choroidal thickness, macular volume and retinal nerve fiber layer in acromegaly patients. ( 28508245 )
2017
15
Long-term Change of Subfoveal Choroidal Thickness in BehAset's Disease Patients with Posterior Uveitis. ( 28080153 )
2017
16
Association of Pediatric Choroidal Neovascular Membranes at the Temporal Edge of Optic Nerve and Retinochoroidal Coloboma. ( 27793604 )
2017
17
Atypical choroid plexus papilloma: clinicopathological and neuroradiological features. ( 28358248 )
2017
18
Lesson of the month 2: A choroid plexus papilloma manifesting as anorexia nervosa in an adult. ( 28365635 )
2017
19
Grossly calcified choroid plexus concealing foramen of Monro meningiomas as an unusual cause of obstructive hydrocephalus. ( 26889294 )
2016
20
Spinal seeding of choroid plexus papilloma. ( 26804647 )
2016
21
MULTIMODAL IMAGING AND HISTOLOGIC CORRELATION OF ISOLATED METASTASIS OF PROSTATE ADENOCARCINOMA TO THE CHOROID. ( 27124795 )
2016
22
Comparison of quantiferon gold and Mantoux test in adults with serpiginous-like choroiditis in northern India. ( 28051010 )
2016
23
Minor trauma resulting in subretinal haemorrhage with choroidal rupture: a case of subtle pseudoxanthoma elasticum in a child. ( 26875857 )
2016
24
Evaluation of Choroidal Thickness in Children With Iron Deficiency Anemia. ( 27806382 )
2016
25
Choroidal fissure acts as an overflow device in cerebrospinal fluid drainage: morphological comparison between idiopathic and secondary normal-pressure hydrocephalus. ( 27941913 )
2016
26
ASSOCIATION BETWEEN AQUEOUS HUMOR CXC MOTIF CHEMOKINE LIGAND 13 LEVELS AND SUBFOVEAL CHOROIDAL THICKNESS IN NORMAL OLDER SUBJECTS. ( 26121407 )
2016
27
Course of disease in multifocal choroiditis lacking sufficient immunosuppression: a case report. ( 27776541 )
2016
28
Optical Coherence Tomography Angiography for Detecting Choroidal Neovascularization Secondary to Punctate Inner Choroidopathy. ( 27977842 )
2016
29
Intravitreal aflibercept for choroidal neovascularisation in angioid streaks. ( 26795411 )
2016
30
Re: Freitas-Neto etA al.: Increased submacular choroidal thickness in active, isolated, extramacular toxoplasmosis (Ophthalmology 2016;123:222-4). ( 27107363 )
2016
31
Detection of Asymptomatic Choroiditis by Fundus Examination in Vogt-Koyanagi-Harada Disease. ( 27379469 )
2016
32
Subfoveal choroidal thickness changes after intravitreal bevacizumab therapy for central serous chorioretinopathy. ( 27982209 )
2016
33
Choroidal melanoma in phacomatosis pigmentovascularis cesioi-8ammea. ( 26858045 )
2016
34
Bilateral choroidal detachment with exudative retinal detachment in a patient with septicaemia. ( 27999127 )
2016
35
Is there a relationship between outer retinal destruction and choroidal changes in cone dystrophy? ( 27982211 )
2016
36
Correlation of Optical Coherence Tomography and Autofluorescence in the Outer Retina and Choroid of Patients With Choroideremia. ( 27403996 )
2016
37
Comparison of Enhanced Depth Imaging and Swept Source Optical Coherence Tomography in Assessment of Choroidal Thickness in Vogt-Koyanagi-Harada Disease. ( 27070488 )
2016
38
Regional Changes in Choroidal Thickness in Branch Retinal Artery Occlusion. ( 27631476 )
2016
39
Angioid streaks complicated by choroidal neovascularization in Paget's disease. ( 27587348 )
2016
40
Choroidal Findings in Eyes With Birdshot Chorioretinitis Using Enhanced-Depth Optical Coherence Tomography. ( 27599125 )
2016
41
Typical Symptoms of Normal-Pressure Hydrocephalus Caused by Choroid Plexus Papilloma in the Cerebellopontine Angle. ( 27913261 )
2016
42
Changes in Choroidal Structures in Eyes with Chronic Central Serous Chorioretinopathy after Half-Dose Photodynamic Therapy. ( 27636093 )
2016
43
SUBFOVEAL CHOROIDAL THICKNESS CHANGE AFTER PARS PLANA VITRECTOMY IN RECENT ONSET RHEGMATOGENOUS RETINAL DETACHMENT. ( 27579730 )
2016
44
Correction: Choroidal Structure in Children with Anisohypermetropic Amblyopia Determined by Binarization of Optical Coherence Tomographic Images. ( 27977804 )
2016
45
Intravitreal Administration of Ranibizumab and Bevacizumab for Choroidal Neovascularization Secondary to Ocular Toxocariasis: A Case Report. ( 27775459 )
2016
46
Retinal Vessel Caliber, Choroidal Thickness and Ocular Pulse Amplitude Measurements in Essential Thrombocythemia. ( 26957845 )
2016
47
Choroidal thickness evaluation of healthy eyes, central serous chorioretinopathy, and fellow eyes using spectral domain optical coherence tomography in Indian population. ( 27905337 )
2016
48
Silent polypoidal choroidal vasculopathy in a patient with angioid streaks. ( 27463636 )
2016
49
Choroidal circulation impairment during the anterior recurrence of Vogt-Koyanagi-Harada disease confirmed with indocyanine green angiography and laser speckle flowgraphy. ( 27079805 )
2016
50
Re: Yonekawa etA al.: Familial exudative vitreoretinopathy: spectral-domain optical coherence tomography of the vitreoretinal interface, retina, and choroid (Ophthalmology 2015;122:2270-7). ( 27107366 )
2016

Variations for Choroiditis

Expression for Choroiditis

Search GEO for disease gene expression data for Choroiditis.

Pathways for Choroiditis

GO Terms for Choroiditis

Cellular components related to Choroiditis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 CFB CFH HTRA1 IL10 TNF
2 extracellular space GO:0005615 9.02 CFB CFH HTRA1 IL10 TNF

Biological processes related to Choroiditis according to GeneCards Suite gene sharing:

(show all 11)
id Name GO ID Score Top Affiliating Genes
1 response to glucocorticoid GO:0051384 9.49 IL10 TNF
2 positive regulation of cytokine secretion GO:0050715 9.48 IL10 TNF
3 negative regulation of mitotic cell cycle GO:0045930 9.46 IL10 TNF
4 negative regulation of interleukin-6 production GO:0032715 9.43 IL10 TNF
5 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.4 IL10 TNF
6 negative regulation of growth of symbiont in host GO:0044130 9.37 IL10 TNF
7 complement activation, alternative pathway GO:0006957 9.32 CFB CFH
8 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.26 IL10 TNF
9 endothelial cell apoptotic process GO:0072577 9.16 IL10 TNF
10 negative regulation of cytokine secretion involved in immune response GO:0002740 8.96 IL10 TNF
11 receptor biosynthetic process GO:0032800 8.62 IL10 TNF

Sources for Choroiditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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