MCID: CHR008
MIFTS: 51

Choroiditis malady

Summaries for Choroiditis

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64Wikipedia, 33MalaCards
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Wikipedia:64 Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina... more...

MalaCards: Choroiditis, also known as choroiditis nos, is related to choroid plexus papilloma and choroid plexus carcinoma. An important gene associated with Choroiditis is SLC46A1 (solute carrier family 46 (folate transporter), member 1), and among its related pathways is the visual cycle I (vertebrates). The compounds cysteine and retinoic acid have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, brain and retina, and related mouse phenotypes are homeostasis/metabolism and vision/eye.

Aliases & Classifications for Choroiditis

Sources:
8Disease Ontology, 43NIH Rare Diseases, 61UMLS, 57SNOMED-CT, 35MeSH
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Aliases & Descriptions:

choroiditis 8 43 61
choroiditis nos 8


External Ids:

Disease Ontology8 DOID:11406
SNOMED-CT57 193449000, 16553002
MeSH35 D002833

Related Diseases for Choroiditis

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Choroiditis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 448)
idRelated DiseaseScoreTop Affiliating Genes
1choroid plexus papilloma31.5S100B, CT49, SYP, IGF2, MUC1, TTR
2choroid plexus carcinoma31.2SMARCB1
3adenocarcinoma30.4TIMP3, CT49, SYP, MUC1
4ependymoma30.4TIMP3, S100B, CT49, SYP, MUC1, TTR
5vitelliform macular dystrophy30.3TIMP3, PRPH2
6blindness30.0TIMP3, CHM, ABCA4, CFH, OAT
7adenoma30.0TIMP3, CT49, SYP, IGF2, MUC1
8rhabdoid tumor30.0SMARCB1, MUC1, IGF2, SYP
9ganglioneuroma30.0S100B, SYP, GFAP
10atypical teratoid rhabdoid tumor30.0SMARCB1
11papillary ependymoma29.8GFAP, SYP, S100B
12paraganglioma29.8S100B, SYP, GFAP
13age related macular degeneration29.8TIMP3, CFH
14primary open angle glaucoma29.8ABCA4
15teratoma29.8GFAP, SMARCB1
16pilocytic astrocytoma29.6TIMP3, S100B, SYP, GFAP
17brain cancer29.6CT49, SYP, GFAP, SMARCB1
18ganglioglioma29.6GFAP, SYP, S100B
19olfactory neuroblastoma29.6S100B, SYP
20giant cell glioblastoma29.6GFAP
21parkinson's disease29.6CHM
22clear cell sarcoma29.6IGF2, S100B
23primary hyperoxaluria29.6CFH, TTR, CT49, TIMP3
24proliferative diabetic retinopathy29.6TIMP3, GFAP
25gyrate atrophy10.8
26multifocal choroiditis10.8
27serpiginous choroiditis10.8
28choroid plexus cyst10.7
29angioid streaks10.6
30coloboma10.6
31central serous chorioretinopathy10.6
32weber syndrome10.5
33sturge-weber syndrome10.5
34n syndrome10.5
35ocular melanoma10.4
36atypical choroid plexus papilloma10.4
37vogt-koyanagi-harada disease10.4
38uveitis10.3
39macular dystrophy10.3
40posterior scleritis10.3
41tuberculosis10.3
42neurofibromatosis10.3
43sympathetic ophthalmia10.3
44toxoplasmosis10.3
45pseudoxanthoma elasticum10.2
46retinitis pigmentosa10.2
47choroid plexus meningioma10.2
48cystoid macular edema10.2
49retinal melanoma10.2
50hyperopia10.2

Graphical network of the top 20 diseases related to Choroiditis:



Diseases related to choroiditis

Clinical Features for Choroiditis

Drugs & Therapeutics for Choroiditis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Choroiditis

Drug clinical trials:

Search ClinicalTrials for Choroiditis

Search NIH Clinical Center for Choroiditis

Search CenterWatch for Choroiditis

Genetic Tests for Choroiditis

Anatomical Context for Choroiditis

Sources:
33MalaCards
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MalaCards organs/tissues related to Choroiditis:

33
Bone marrow, Brain, Retina, Lung, Pituitary

Animal Models for Choroiditis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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Publications for Choroiditis

Sources:
51PubMed
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Articles related to Choroiditis:

(show top 50)    (show all 368)
idTitleAuthorsYear
1
Adalimumab in serpiginous choroiditis. (23480603)
2013
2
Idiopathic multifocal choroiditis: a comment on present and past nomenclature. (23026849)
2013
3
A diagnostic dilemma: infectious versus noninfectious multifocal choroiditis with panuveitis. (23514267)
2013
4
Solitary idiopathic choroiditis: findings on enhanced depth imaging optical coherence tomography in 10 cases. (23246121)
2013
5
Retrospective analysis of the natural history and management of serpiginous choroiditis in Australia and New Zealand. (24330142)
2013
6
Imaging in the diagnosis and management of serpiginous choroiditis. (22954945)
2012
7
Eales disease associated with serpiginous choroiditis. (23143459)
2012
8
Nested PCR-positive tubercular ampiginous choroiditis: a case report. (22621208)
2012
9
Tuberculosis-related choriocapillaritis (multifocal-serpiginous choroiditis): follow-up and precise monitoring of therapy by indocyanine green angiography. (22249644)
2012
10
Uveitis with occult choroiditis due to Mycobacterium kansasii: limitations of interferon-gamma release assay (IGRA) tests (case report and mini-review on ocular non-tuberculous mycobacteria and IGRA cross-reactivity). (22661050)
2012
11
Classification of choroiditis based on inflammatory lesion process rather than fundus appearance: enhanced comprehension through the ICGA concepts of the iceberg and jellyfish effects. (22495994)
2012
12
Tubercular serpiginous-like choroiditis. (22675097)
2011
13
Comparison on clinical characteristics of multifocal choroiditis and punctate inner choriodopathy. (21913348)
2011
14
Bevacizumab vs photodynamic therapy for choroidal neovascularization in multifocal choroiditis. (20837791)
2010
15
Clinical features of tuberculous serpiginouslike choroiditis in contrast to classic serpiginous choroiditis. (20625045)
2010
16
Choroiditis in a patient with multiple sclerosis. (19065419)
2008
17
Photodynamic therapy for juxtafoveal choroidal neovascularization associated with multifocal choroiditis. (16386985)
2006
18
Syphilis presenting as acute multifocal retino-choroiditis. (16816270)
2006
19
Multifocal choroiditis: ocular TB or side-effects of anti-TB therapy? (15889575)
2004
20
Multifocal choroiditis and acute posterior multifocal placoid pigment epitheliopathy occurring in the same patient. (15596597)
2004
21
Multifocal choroiditis with subretinal fibrosis before, during and after pregnancy. (12880467)
2003
22
Imaging analysis with optical coherence tomography: relevance for submacular surgery in high myopia and in multifocal choroiditis. (11927853)
2002
23
Paediatric varicella choroiditis. (9893606)
1998
24
Visual prognosis of multifocal choroiditis, punctate inner choroidopathy, and the diffuse subretinal fibrosis syndrome. (8684800)
1996
25
Infectious choroiditis in the acquired immune deficiency syndrome. (8989610)
1996
26
Multifocal inner choroiditis. (8435651)
1993
27
Choroiditis and meningitis in experimental murine infection with Listeria monocytogenes. (1425736)
1992
28
Epstein-Barr virus antibodies in multifocal choroiditis and panuveitis. (1656755)
1991
29
Lack of the HLA-DR2 specificity in multifocal choroiditis and panuveitis. (1697479)
1990
30
Multifocal choroiditis. (2228476)
1990
31
Schistosomotic choroiditis. II. Report of first case. (3994947)
1985
32
The long-term course of multifocal choroiditis (presumed ocular histoplasmosis). (7246698)
1981
33
Septic choroiditis with serous detachment of the retina in dogs. (700961)
1978
34
Serpiginous (geographic) choroiditis. (1269358)
1976
35
Further experience with partial photocoagulation of the neovascular net in histoplasmic choroiditis. (1239426)
1975
36
Photocoagulation of presumed histoplasmic choroiditis. (1239425)
1975
37
Delayed diffuse exudative aseptic choroiditis produced by pressure of encircling silastic band without evacuation of subretinal fluid in retinal detachment surgery. (4466516)
1974
38
The geographic localization of presumed histoplasmic choroiditis. (4708635)
1973
39
Choroiditis treated by surgical removal of unerupted impacted maxillary third molar: report of case. (4508614)
1973
40
Coccidioidal choroiditis following renal transplantation. (4567017)
1972
41
Photocoagulation and other therapy for histoplasmic choroiditis. (4385814)
1968
42
Presumed histoplasmic choroiditis. (6024422)
1967
43
Tuberculous choroiditis associated with xanthoma tuberosum. (14914849)
1952
44
FAMILIAL HYALINE DYSTROPHY IN THE FUNDUS OCULI OR DOYNE'S FAMILY HONEYCOMB "CHOROIDITIS". (18169427)
1937
45
Tay's "Guttate Choroiditis". (19988967)
1932
46
Choroiditis Juxta-Papillaris. (19986351)
1928
47
Metastatic Choroiditis from Focal Infection. (16692639)
1923
48
Atypical Disseminated Choroiditis Due to Disease of the Accessory Sinuses. (16692484)
1919
49
Choroiditis commencing as a Ring surrounding the Macula. (19978224)
1914
50
Use of Mercury in Traumatic Irido-Choroiditis. (16691900)
1896

Genetic Variations for Choroiditis

Expression for genes affiliated with Choroiditis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Choroiditis

Search GEO for disease gene expression data for Choroiditis.

Pathways for genes affiliated with Choroiditis

Sources:
38NCBI BioSystems Database, 54Reactome
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Pathways related to Choroiditis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.8TTR, ABCA4

Compounds for genes affiliated with Choroiditis

Sources:
45Novoseek, 24HMDB, 60Tocris Bioscience, 11DrugBank, 50PharmGKB, 29IUPHAR
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Compounds related to Choroiditis according to GeneCards/GeneDecks:

(show top 50)    (show all 53)
idCompoundScoreTop Affiliating Genes
1cysteine4512.9CFH, TIMP3, S100B, HTR2C, CT49, OPTC
2retinoic acid45 2413.4TIMP3, S100B, CT49, SYP, IGF2, MUC1
3serine4512.3S100B, HTR2C, CT49, SYP, IGF2, MUC1
4paraffin4512.2TIMP3, S100B, CT49, SYP, IGF2, MUC1
5testosterone45 60 11 2415.2TIMP3, S100B, CT49, SYP, IGF2, MUC1
6dexamethasone45 50 29 1115.2TIMP3, S100B, SYP, IGF2, MUC1, TTR
7glutamate4512.2TIMP3, S100B, HTR2C, SYP, IGF2, TTR
8estrogen4512.2TIMP3, S100B, CT49, SYP, IGF2, MUC1
9lipid4512.2TIMP3, S100B, HTR2C, SYP, CHM, MUC1
10tyrosine4512.1TIMP3, S100B, HTR2C, SYP, IGF2, MUC1
11glutamine4512.1TIMP3, S100B, SYP, IGF2, TTR, GFAP
12progesterone45 60 29 11 2416.0TIMP3, S100B, CT49, SYP, IGF2, MUC1
13vegf4512.0TIMP3, S100B, CT49, SYP, IGF2, MUC1
14glucose4512.0TIMP3, S100B, IGF2, MUC1, TTR, GFAP
15estradiol45 11 2413.9TIMP3, CT49, SYP, IGF2, MUC1, GFAP
16creatinine4511.8S100B, SYP, IGF2, MUC1, TTR, GFAP
17cholesterol45 29 11 2414.8SYP, MUC1, ABCA4, TTR, GFAP, CFH
18arginine4511.8TIMP3, S100B, IGF2, TTR, GFAP, OAT
19zinc45 2412.8S100B, CT49, IGF2, TTR, GFAP, CFH
20alanine4511.7S100B, CT49, IGF2, TTR, GFAP, CFH
21dbc-amp4511.7TIMP3, S100B, SYP, IGF2, GFAP
22acth4511.7GFAP, MUC1, IGF2, SYP, S100B
23agar4511.7GFAP, TTR, MUC1, IGF2, CT49
24gaba4511.7S100B, HTR2C, SYP, GFAP, OAT
25norepinephrine45 11 2413.7S100B, HTR2C, SYP, IGF2, TTR
26glycogen45 2412.6S100B, SYP, IGF2, MUC1, GFAP
27dopamine45 29 11 2414.6S100B, HTR2C, SYP, TTR, GFAP
28cisplatin45 50 60 1114.6SYP, IGF2, MUC1, GFAP, CFH
29thymidine45 2412.6S100B, CT49, IGF2, MUC1, GFAP
30s 1004511.6S100B, SYP, MUC1, GFAP
31reticulin4511.6S100B, SYP, MUC1, GFAP
32aspartate4511.6S100B, PRPH2, TTR, GFAP, OAT
33hematoxylin4511.5S100B, SYP, MUC1, GFAP
34adenylate4511.5S100B, HTR2C, IGF2, TTR, GFAP
35formaldehyde45 2412.5S100B, SYP, MUC1, GFAP
36eosin4511.4S100B, MUC1, GFAP
37mucicarmine4511.4S100B, SYP, MUC1
38b 7234511.3S100B, SYP, MUC1
39methionine4511.3TIMP3, S100B, TTR, GFAP
40forskolin45 50 1113.2GFAP, CT49
41guanidine hydrochloride4511.2TTR, MUC1, IGF2
42ethanol45 50 11 2414.2S100B, SYP, MUC1, GFAP
43lithium45 50 11 2414.2MUC1, SYP, HTR2C
44silver4511.1CT49, SYP, GFAP
45phospholipid4511.1ABCA4, MUC1, SYP, S100B
46polyethylene glycol4511.1GFAP, MUC1, IGF2
47n-acetylaspartate4511.1GFAP, SYP
48acetylcholine45 50 29 11 2415.0S100B, HTR2C, SYP, GFAP
49glycosaminoglycan4511.0CFH, IGF2, TIMP3
502,3-cyclic nucleotide4510.5GFAP, S100B

GO Terms for genes affiliated with Choroiditis

Sources:
16Gene Ontology
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Biological processes related to Choroiditis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1visual perceptionGO:00760111.0OAT, ABCA4, CHM, PRPH2, TIMP3
2cellular response to organic substanceGO:07131010.8SYP, TIMP3

Products for genes affiliated with Choroiditis

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Sources for Choroiditis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet