MCID: CHR008
MIFTS: 43

Choroiditis

Categories: Rare diseases, Eye diseases

Aliases & Classifications for Choroiditis

MalaCards integrated aliases for Choroiditis:

Name: Choroiditis 12 50 42 14 69

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology 12 DOID:11406
ICD10 33 H30.9
MeSH 42 D002833
NCIt 47 C35111
SNOMED-CT 64 16553002 193449000
UMLS 69 C0008526

Summaries for Choroiditis

MalaCards based summary : Choroiditis is related to lymphoma and cryptococcosis. An important gene associated with Choroiditis is CFH (Complement Factor H), and among its related pathways/superpathways are Innate Lymphoid Cell Differentiation Pathways and Pertussis. The drugs Dexamethasone and Bevacizumab have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and endothelial.

Wikipedia : 72 Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina... more...

Related Diseases for Choroiditis

Diseases related to Choroiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 805)
id Related Disease Score Top Affiliating Genes
1 lymphoma 29.4 IL10 TNF
2 cryptococcosis 29.2 IL10 TNF
3 dysphagia 28.9 IL10 TNF
4 glioblastoma multiforme 28.9 IL10 TNF
5 hypospadias 28.9 IL10 TNF
6 gastric ulcer 28.8 IL10 TNF
7 colon adenocarcinoma 28.8 IL10 TNF
8 macular degeneration, age-related, 1 28.7 ARMS2 CFB CFH HTRA1 TNF
9 pulmonary embolism 28.0 IL10 TNF
10 choroid plexus papilloma 12.3
11 choroid disease 12.2
12 serpiginous choroiditis 12.2
13 choroid plexus cancer 12.2
14 gyrate atrophy of choroid and retina with or without ornithinemia 12.2
15 partial central choroid dystrophy 12.1
16 choroid plexus cyst 12.1
17 multifocal choroiditis 12.1
18 choroidal sclerosis 12.0
19 choroidal dystrophy, central areolar 2 12.0
20 ataxia - hypogonadism - choroidal dystrophy 12.0
21 choroid spindle cell melanoma 11.9
22 atypical choroid plexus papilloma 11.9
23 malignant choroid melanoma 11.9
24 choroid plexus meningioma 11.8
25 hereditary choroidal atrophy 11.8
26 birdshot chorioretinopathy 11.7
27 choroideremia 11.7
28 choroid mixed cell melanoma 11.7
29 adult choroid plexus cancer 11.7
30 central gyrate choroidal dystrophy 11.7
31 choroid plexus calcification and mental retardation 11.7
32 total circumpapillary dystrophy of choroid 11.7
33 choroid epithelioid cell melanoma 11.7
34 childhood choroid plexus cancer 11.7
35 choroid necrotic melanoma 11.7
36 diffuse secondary choroid atrophy 11.6
37 partial circumpapillary choroid dystrophy 11.6
38 thumb, hypoplastic, with choroid coloboma, poorly developed antihelix, and deafness 11.6
39 senile atrophy of choroid 11.6
40 angioid streaks of choroid 11.6
41 retinochoroidal coloboma 11.6
42 uveal melanoma 11.6
43 chorioretinitis 11.4
44 coloboma, ocular 11.3
45 coloboma 11.3
46 macular dystrophy, vitelliform, 3 11.3
47 central serous chorioretinopathy 11.2
48 ocular melanoma 11.2
49 punctate inner choroidopathy 11.1
50 pars planitis 11.1

Graphical network of the top 20 diseases related to Choroiditis:



Diseases related to Choroiditis

Symptoms & Phenotypes for Choroiditis

Drugs & Therapeutics for Choroiditis

Drugs for Choroiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 79)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-02-2 5743
2
Bevacizumab Approved, Investigational Phase 4,Phase 3 216974-75-3
3 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
4 Hormones Phase 4,Phase 3,Phase 2,Phase 1
5 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
6 Antiemetics Phase 4,Phase 3,Phase 2
7 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
8 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2
9 Autonomic Agents Phase 4,Phase 3,Phase 2
10 BB 1101 Phase 4,Phase 3,Phase 2
11 Dexamethasone acetate Phase 4,Phase 3,Phase 2 1177-87-3
12 Gastrointestinal Agents Phase 4,Phase 3,Phase 2
13 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
14 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2
15 Immunosuppressive Agents Phase 4,Phase 3,Phase 1,Phase 2
16 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
17
protease inhibitors Phase 4,Phase 3,Phase 2
18 Angiogenesis Inhibitors Phase 4,Phase 3,Phase 1,Phase 2
19 Angiogenesis Modulating Agents Phase 4,Phase 3,Phase 1,Phase 2
20 Adrenocorticotropic Hormone Phase 4
21 beta-endorphin Phase 4
22 Melanocyte-Stimulating Hormones Phase 4
23
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
24
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
25
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
26
Pyrimethamine Approved, Vet_approved Phase 3 58-14-0 4993
27
Sulfadiazine Approved, Vet_approved Phase 3 68-35-9 5215
28
Mycophenolate mofetil Approved, Investigational Phase 3 128794-94-5 5281078
29
Mycophenolic acid Approved Phase 3 24280-93-1 446541
30
Prednisone Approved, Vet_approved Phase 3,Phase 2 53-03-2 5865
31
Methotrexate Approved Phase 3,Phase 1,Phase 2 1959-05-2, 59-05-2 126941
32
Triamcinolone Approved, Vet_approved Phase 3,Phase 1,Phase 2 124-94-7 31307
33
Fluocinolone Acetonide Approved, Investigational, Vet_approved Phase 3 67-73-2 6215
34
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 1,Phase 2 59-30-3 6037
35
leucovorin Approved, Nutraceutical Phase 3,Phase 1,Phase 2 58-05-9 143 6006
36 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
37 Anti-Infective Agents Phase 3,Phase 2,Phase 1
38 Antimalarials Phase 3
39 Antiparasitic Agents Phase 3
40 Antiprotozoal Agents Phase 3
41 Clindamycin palmitate Phase 3
42 Clindamycin phosphate Phase 3
43 Folic Acid Antagonists Phase 3,Phase 1,Phase 2
44 Methylprednisolone acetate Phase 3
45 Methylprednisolone Hemisuccinate Phase 3
46 Neuroprotective Agents Phase 3
47 Prednisolone acetate Phase 3
48 Prednisolone hemisuccinate Phase 3
49 Prednisolone phosphate Phase 3
50 Protective Agents Phase 3

Interventional clinical trials:

(show all 35)

id Name Status NCT ID Phase Drugs
1 Intravitreal Bevacizumab in Recalcitrant Inflammatory Ocular Neovascularization Completed NCT00645697 Phase 4
2 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients Completed NCT02764697 Phase 4 H.P. ACTHAR SUBCUTANEOUS GEL INJECTION
3 Study of the Effectiveness of Ozurdex for the Control of Uveitis Recruiting NCT02049476 Phase 4 Dexamethasone pellet
4 To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis Unknown status NCT00372294 Phase 3 pyrimethamine-sulfadiazine + prednisolone;Clindamycin+Dexamethasone
5 Intravitreal Bevacizumab for Inflammatory Neovascular Membranes Completed NCT00407121 Phase 3 Bevacizumab
6 A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis Completed NCT00404742 Phase 3 Placebo;LX211;LX211;LX211
7 A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis Completed NCT00404612 Phase 3 Placebo;LX211;LX211;LX211
8 A Study of the Safety and Efficacy of a New Treatment for Non-Infectious Intermediate or Posterior Uveitis Completed NCT00333814 Phase 2, Phase 3 Dexamethasone;dexamethasone;Sham injection
9 Myfortic for the Treatment of Non-infectious Intermediate Uveitis Completed NCT01092533 Phase 3 Myfortic;Decortin
10 Randomized, Controlled Trial to Test the Efficacy of Interferon Beta in the Treatment of Intermediate Uveitis Completed NCT00344253 Phase 3 Interferon beta;Methotrexate
11 Suprachoroidal Injection of CLS-TA in Subjects Non-infectious Uveitis Active, not recruiting NCT03097315 Phase 3
12 A Controlled, Multi-center Study of the Utilization and Safety of the MK II Inserter and the Safety of the FAI Insert in Subjects With Non-infectious Uveitis Affecting the Posterior Segment of the Eye Active, not recruiting NCT02748512 Phase 3 FAI insert
13 Safety and Efficacy Study of a Fluocinolone Acetonide Intravitreal (FAI) Insert in Subjects With Chronic Non-infectious Posterior Uveitis Active, not recruiting NCT02746991 Phase 3 Sham Injection;FAI Insert
14 Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert Active, not recruiting NCT01694186 Phase 3 FAI insert;Sham injection
15 Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis Active, not recruiting NCT02595398 Phase 3 4mg CLS-TA Suprachoriodal Injection;Sham Procedure
16 Treatment of Exudative and Vasogenic Chorioretinal Diseases Including Variants of AMD and Other CNV Related Maculopathy Completed NCT00470977 Phase 1, Phase 2 ranibizumab injection (0.5 mg)
17 Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis Completed NCT01789320 Phase 1, Phase 2 triamcinolone acetonide (Triesence®)
18 Safety,Tolerability and Efficacy of Intravitreal LFG316 in Patients With Active Non-infectious Intermediate-, posterior-or Panuveitis , Completed NCT01526889 Phase 2 LFG316;Conventional Therapy
19 Safety and Efficacy of AIN457 in Noninfectious Uveitis Completed NCT00685399 Phase 2 AIN457;AIN 457;AIN457
20 Effect of Spironolactone in Treating Chronic Non-resolutive Central Serous Chorioretinitis Completed NCT01552044 Phase 1, Phase 2 Spironolactone;Placebo
21 Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis Completed NCT02255032 Phase 2 4 mg CLS-TA;0.8 mg CLS-TA
22 Evaluation of Birdshot Retine Choroidopathy Treatment by Either Steroid or Interferon alpha2a Completed NCT00508040 Phase 2 interferon alpha 2a;prednisone
23 Intravitreal Sirolimus as Therapeutic Approach to Uveitis Recruiting NCT01280669 Phase 2 Intravitreal injection 440mcg;Intravitreal injection of sirolimus 880mcg
24 Study of the Safety, Tolerability, and Bioactivity of Tocilizumab On Patients With Non-infectious UVEITIS: The STOP-UVEITIS Study Active, not recruiting NCT01717170 Phase 1, Phase 2 Tocilizumab
25 Safety &Efficacy of CF101 to Subjects With Uveitis Not yet recruiting NCT01905124 Phase 2 CF101;Placebo
26 Safety and Preliminary Efficacy Study of V404 PDS in Uveitis Terminated NCT02125266 Phase 1, Phase 2 V404
27 Sirolimus as Therapeutic Approach to Uveitis Unknown status NCT00908466 Phase 1 Sirolimus (rapamycin);Sirolimus (rapamycin)
28 Evaluation and Treatment of Patients With Inflammatory Eye Diseases Completed NCT00006188
29 Retisert and Cataract Surgery in Patients With Severe Uveitis Completed NCT00570830
30 Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis Completed NCT02843438 Anti-toxoplasmosis treatment;Anti-inflammatory treatments
31 Quality of Life in Patients With Intermediate Uveitis Completed NCT01314469
32 Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301 Recruiting NCT02952001
33 Variations in Retinal Nerve Fiber Layer Thickness During Uncomplicated Anterior and Intermediate Uveitis Not yet recruiting NCT02879084
34 Intravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMD Withdrawn NCT01256580 Bevacizumab (Avastin; Genentech, Inc.);Bevacizumab, Dexamethasone, Verteporfin Photodynamic Therapy
35 Postnatal HCMV Infection in Very Preterm Infants. Implications, Morbidity, Growth and Neurodevelopmental Outcomes. Withdrawn NCT01151462

Search NIH Clinical Center for Choroiditis

Cochrane evidence based reviews: choroiditis

Genetic Tests for Choroiditis

Anatomical Context for Choroiditis

MalaCards organs/tissues related to Choroiditis:

39
Retina, Eye, Endothelial, Brain, Testes, Lung, Thyroid

Publications for Choroiditis

Articles related to Choroiditis:

(show top 50) (show all 2694)
id Title Authors Year
1
Subfoveal Choroidal Thickness in Central Serous Chorioretinopathy: A Meta-Analysis. ( 28076442 )
2017
2
Neovascular glaucoma after proton beam therapy of choroidal melanoma: incidence and risk factors. ( 28721444 )
2017
3
Identification of ANGPT2 as a New Gene for Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in the Chinese and Japanese Populations. ( 28192798 )
2017
4
A choroid plexus cyst in the fourth ventricle of a Sprague-Dawley rat. ( 28798531 )
2017
5
Relationship between Choroidal Thickness and Visual Field Impairment in Acute Zonal Occult Outer Retinopathy. ( 28758030 )
2017
6
Intravitreal aflibercept for choroidal neovascularization associated with chorioretinitis: a pilot study. ( 28769551 )
2017
7
Long-term Change of Subfoveal Choroidal Thickness in BehAset's Disease Patients with Posterior Uveitis. ( 28080153 )
2017
8
Choroidal thickness in traumatic optic neuropathy. ( 28937859 )
2017
9
Is Choroidal or Scleral Thickness Related to Myopic Macular Degeneration? ( 28166316 )
2017
10
Role of Angiography in Systemic Lupus Erythematosus-Induced Choroiditis. ( 28362518 )
2017
11
Atypical choroid plexus papilloma: spontaneous resolution of diffuse leptomeningeal contrast enhancement after primary tumor removal in 2 pediatric cases. ( 28686125 )
2017
12
OTX2 Defines a Subgroup of Atypical Teratoid Rhabdoid Tumors With Close Relationship to Choroid Plexus Tumors. ( 28025236 )
2017
13
Sturge-Weber Syndrome Associated with Monolateral Ocular Melanocytosis, Iris Mammillations, and Diffuse Choroidal Haemangioma. ( 28868033 )
2017
14
Polarization-Sensitive Optical Coherence Tomographic Documentation of Choroidal Melanin Loss in Chronic Vogt-Koyanagi-Harada Disease. ( 28863408 )
2017
15
Interactions of antisera to different Chlamydia and Chlamydophila species with the ribosomal protein RPS27a correlate with impaired protein synthesis in a human choroid plexus papilloma cell line. ( 28913776 )
2017
16
Detection of nonexudative choroidal neovascularization secondary to angioid streaks using optical coherence tomography angiography. ( 28574138 )
2017
17
Choroidal neovascularization in multifocal choroiditis after dabrafenib and trametinib. ( 28777388 )
2017
18
Paradoxical worsening of a case of TB subretinal abscess with serpiginous-like choroiditis following the initiation of antitubercular therapy. ( 28820170 )
2017
19
Assessment of peripapillary choroidal thickness in primary open-angle glaucoma patients with choroidal vascular prominence. ( 28929241 )
2017
20
Choroidal Thickness Variation According to Refractive Error Measured by Spectral Domain-optical Coherence Tomography in Korean Children. ( 28367044 )
2017
21
Choroidal Vasculature in Bietti Crystalline Dystrophy With CYP4V2 Mutations and in Retinitis Pigmentosa With EYS Mutations. ( 28763560 )
2017
22
Choroidal Imaging with Swept-Source Optical Coherence Tomography in Patients with Birdshot Chorioretinopathy: Choroidal Reflectivity and Thickness. ( 28456419 )
2017
23
Multifocal Choroiditis with Retinal Vasculitis, Optic Neuropathy, and Keratoconus in a Young Saudi Male. ( 28936058 )
2017
24
Automated Evaluation of Choroidal Thickness and Minimum Rim Width Thickness in Nonarteritic Anterior Ischemic Optic Neuropathy. ( 28885450 )
2017
25
Choroid plexus cauterization on treatment of hydranencephaly and maximal hydrocephalus. ( 28597309 )
2017
26
The effect on choroidal changes of the route of systemic corticosteroids in acute Vogt-Koyanagi-Harada disease. ( 28382438 )
2017
27
Choroidal thickness measurements in children with isolated growth hormone deficiency. ( 28912516 )
2017
28
The relationship between scleral staphyloma and choroidal thinning in highly myopic eyes: The Beijing Eye Study. ( 28852194 )
2017
29
How to Differentiate Myopic Choroidal Neovascularization, Idiopathic Multifocal Choroiditis, and Punctate Inner Choroidopathy Using Clinical and Multimodal Imaging Findings. ( 28297030 )
2017
30
A Primary Pigmented Choroid Plexus Papilloma Located Within the Sella Turcica: Case Report and Literature Review. ( 28684370 )
2017
31
A choroid plexus papilloma manifesting as anorexia nervosa in an adult. ( 28765434 )
2017
32
Intravitreal anti-VEGF treatment for choroidal neovascularization secondary to punctate inner choroidopathy. ( 28424992 )
2017
33
Long-Term Follow-Up of Choroidal Neovascularization due to Angioid Streaks with pro re nata Intravitreal Anti-VEGF Treatment. ( 28641290 )
2017
34
Multifocal Choroiditis with Peripheral Subretinal Fibrosis and Optic Nerve Involvement. ( 28734337 )
2017
35
Multimodal Imaging Including Optical Coherence Tomography Angiography in Serpiginous Choroiditis. ( 28281863 )
2017
36
Dengue associated choroiditis: a rare entity. ( 28560576 )
2017
37
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FOR THE DETECTION OF SECONDARY CHOROIDAL NEOVASCULARIZATION IN VITELLIFORM MACULAR DYSTROPHY. ( 28817420 )
2017
38
Atypical choroid plexus papilloma: clinicopathological and neuroradiological features. ( 28358248 )
2017
39
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY SHOWS INNER CHOROIDAL ISCHEMIA IN ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY. ( 27759710 )
2017
40
Sturge-Weber Syndrome with Choroidal Hemangioma. ( 28584769 )
2017
41
Spinal drop metastasis from a benign fourth ventricular choroid plexus papilloma in a pediatric patient: case report. ( 28841111 )
2017
42
The effect of strabismus surgery on choroidal thickness. ( 28885671 )
2017
43
Treating Cerebrospinal Fluid Rhinorrhea without Dura Repair: A Case Report of Posterior Fossa Choroid Plexus Papilloma and Review of the Literature. ( 28866068 )
2017
44
Relationship between choroidal blood flow velocity and choroidal thickness in patients with regression of acute central serous chorioretinopathy. ( 28889224 )
2017
45
Efficacy and safety of conbercept as a primary treatment for choroidal neovascularization secondary to punctate inner choroidopathy. ( 28606070 )
2017
46
Erratum: Intravitreal aflibercept for choroidal neovascularization associated with chorioretinitis: a pilot study [Corrigendum]. ( 28894355 )
2017
47
Choroid Plexitis and Ependymitis by Magnetic Resonance Imaging are Biomarkers of Neuronal Damage and Inflammation in HIV-negative Cryptococcal Meningoencephalitis. ( 28835663 )
2017
48
CHOROIDAL MELANOMA, SECTOR MELANOCYTOSIS, AND RETINAL PIGMENT EPITHELIAL MICRODETACHMENTS IN BIRT-HOGG-DUBA8 SYNDROME. ( 28541267 )
2017
49
Evaluation of macular and peripapillary choroidal thickness, macular volume and retinal nerve fiber layer in acromegaly patients. ( 28508245 )
2017
50
Long-Term Follow-Up of Polypoidal Choroidal Vasculopathy Secondary to Angioid Streaks Treated by Intravitreal Aflibercept and Ranibizumab. ( 28512425 )
2017

Variations for Choroiditis

Expression for Choroiditis

Search GEO for disease gene expression data for Choroiditis.

Pathways for Choroiditis

GO Terms for Choroiditis

Cellular components related to Choroiditis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 CFB CFH HTRA1 IL10 TNF
2 extracellular space GO:0005615 9.02 CFB CFH HTRA1 IL10 TNF

Biological processes related to Choroiditis according to GeneCards Suite gene sharing:

(show all 11)
id Name GO ID Score Top Affiliating Genes
1 response to glucocorticoid GO:0051384 9.49 IL10 TNF
2 negative regulation of mitotic cell cycle GO:0045930 9.48 IL10 TNF
3 positive regulation of cytokine secretion GO:0050715 9.46 IL10 TNF
4 negative regulation of interleukin-6 production GO:0032715 9.43 IL10 TNF
5 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.4 IL10 TNF
6 negative regulation of growth of symbiont in host GO:0044130 9.37 IL10 TNF
7 complement activation, alternative pathway GO:0006957 9.32 CFB CFH
8 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.26 IL10 TNF
9 endothelial cell apoptotic process GO:0072577 9.16 IL10 TNF
10 negative regulation of cytokine secretion involved in immune response GO:0002740 8.96 IL10 TNF
11 receptor biosynthetic process GO:0032800 8.62 IL10 TNF

Sources for Choroiditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
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48 NDF-RT
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54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
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67 TGDB
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70 UMLS via Orphanet
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