CRCC
MCID: CHR177
MIFTS: 37

Chromophobe Renal Cell Carcinoma (CRCC) malady

Rare diseases, Nephrological diseases, Cancer diseases categories

Summaries for Chromophobe Renal Cell Carcinoma

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NIH Rare Diseases:42 Chromophobe renal cell carcinoma is a subtype of the most common form of kidney cancer called renal cell carcinoma (rcc). chromophobe renal cell carcinoma makes up about 4-6% of rcc, and it is frequently diagnosed between ages 50 and 60. it is thought to have a more favorable prognosis than clear cell rcc, which is the main subtype of rcc. last updated: 11/2/2010

MalaCards based summary: Chromophobe Renal Cell Carcinoma, also known as chromophobe renal cell adenocarcinoma, is related to renal oncocytoma and renal cell carcinoma. An important gene associated with Chromophobe Renal Cell Carcinoma is PSMB9 (proteasome (prosome, macropain) subunit, beta type, 9), and among its related pathways are WNT Signaling and Presenilin-Mediated Signaling. The compound aprotinin have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and bone marrow, and related mouse phenotype immune system.

Aliases & Classifications for Chromophobe Renal Cell Carcinoma

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Sources:
31LifeMap Discovery®, 42NIH Rare Diseases, 48Orphanet, 61UMLS, 27ICD10 via Orphanet, 62UMLS via Orphanet
See all sources

Chromophobe Renal Cell Carcinoma, Aliases & Descriptions:

Name: Chromophobe Renal Cell Carcinoma 31 42 48 61
Chromophobe Renal Cell Adenocarcinoma 48
 
Chrcc 42
Crcc 42


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Nephrological diseases


External Ids:

ICD10 via Orphanet27 C64
UMLS via Orphanet62 C1266042

Related Diseases for Chromophobe Renal Cell Carcinoma

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Graphical network of the top 20 diseases related to Chromophobe Renal Cell Carcinoma:



Diseases related to chromophobe renal cell carcinoma

Symptoms for Chromophobe Renal Cell Carcinoma

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Drugs & Therapeutics for Chromophobe Renal Cell Carcinoma

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Drug clinical trials:

Search ClinicalTrials for Chromophobe Renal Cell Carcinoma

Search NIH Clinical Center for Chromophobe Renal Cell Carcinoma

Genetic Tests for Chromophobe Renal Cell Carcinoma

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Anatomical Context for Chromophobe Renal Cell Carcinoma

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MalaCards organs/tissues related to Chromophobe Renal Cell Carcinoma:

32
Kidney, Liver, Bone marrow, Bone, Lymph node, Colon, Thyroid

Animal Models for Chromophobe Renal Cell Carcinoma or affiliated genes

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MGI Mouse Phenotypes related to Chromophobe Renal Cell Carcinoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.1HNF1B, PSMB9, PRSS8, MME, FLCN

Publications for Chromophobe Renal Cell Carcinoma

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Articles related to Chromophobe Renal Cell Carcinoma:

(show top 50)    (show all 200)
idTitleAuthorsYear
1
Clinical behavior of chromophobe renal cell carcinoma is less aggressive than that of clear cell renal cell carcinoma, independent of Fuhrman grade or tumor size. (25178561)
2014
2
Monocyte-derived dendritic cells reflect the immune functional status of a chromophobe renal cell carcinoma patient: Could it be a general phenomenon? (25314913)
2014
3
Omental Nodular Deposits of Recurrent Chromophobe Renal Cell Carcinoma Seen on FDG-PET/CT. (25337437)
2014
4
Predominantly tubular chromophobe renal cell carcinoma: an unusual histological presentation reminiscent of a neuroendocrine tumor. (23704098)
2013
5
Dysregulation of the mammalian target of rapamycin pathway in chromophobe renal cell carcinomas. (23953228)
2013
6
Interobserver reproducibility of a grading system for chromophobe renal cell carcinoma. (23058995)
2013
7
Chromophobe renal cell carcinoma, oncocytic variant: a proposal of a new variant giving a critical diagnostic pitfall in diagnosing renal oncocytic tumors. (23338778)
2013
8
Colon metastasis of chromophobe renal cell carcinoma with sarcomatoid change. (22964308)
2012
9
Chromophobe renal cell carcinoma with neuroendocrine differentiation and sarcomatoid change. (21884307)
2011
10
Chromophobe renal cell carcinoma with prominent lymph node metastasis and polysomy of chromosome 21: poorly differentiated form or "presarcomatoid" form? (21922389)
2011
11
Chromophobe renal cell carcinoma with prolonged response to sequential sunitinib and everolimus. (21245426)
2011
12
Two cases of eosinophilic variant chromophobe renal cell carcinoma, with a rare association of right atrial myxoma in one of them. (22219567)
2011
13
Temsirolimus in metastatic chromophobe renal cell carcinoma after interferon and sorafenib therapy. (21273619)
2011
14
Diagnostic Utility of Caveolin-1 and MOC-31 in Distinguishing Chromophobe Renal Cell Carcinoma from Renal Oncocytoma. (21379425)
2011
15
Dedifferentiated chromophobe renal cell carcinoma with massive osteosarcoma-like divergent differentiation: a singular entity in the spectrum of retroperitoneal calcifying tumors. (19098016)
2010
16
Molecular pathology of chromophobe renal cell carcinoma: a review. (20590942)
2010
17
Chromophobe renal cell carcinoma with liposarcomatous dedifferentiation - report of a unique case. (20606735)
2010
18
MRI features of renal oncocytoma and chromophobe renal cell carcinoma. (21098174)
2010
19
Genomic expression and single-nucleotide polymorphism profiling discriminates chromophobe renal cell carcinoma and oncocytoma. (20462447)
2010
20
Diagnostic usefulness of fluorescent cytogenetics in differentiating chromophobe renal cell carcinoma from renal oncocytoma: a validation study combining metaphase and interphase analyses. (20023267)
2010
21
Can renal oncocytoma be distinguished from chromophobe renal cell carcinoma by the presence of fibrous capsule? (20024582)
2010
22
Gene expression profiling of chromophobe renal cell carcinomas and renal oncocytomas by Affymetrix GeneChip using pooled and individual tumours. (19680475)
2009
23
A giant chromophobe renal cell carcinoma exceeding 10 kg. (20002842)
2009
24
Immunohistochemical stain for cytokeratin 7, S100A1 and claudin 8 is valuable in differential diagnosis of chromophobe renal cell carcinoma from renal oncocytoma. (19302533)
2009
25
CCND1 rearrangements and cyclin D1 overexpression in renal oncocytomas: frequency, clinicopathologic features, and utility in differentiation from chromophobe renal cell carcinoma. (19386349)
2009
26
Chromophobe renal cell carcinoma with neuroendocrine differentiation. (19024610)
2008
27
Chromophobe renal cell carcinoma with calcification: Report of a case with rare finding on aspiration smears. (18677748)
2008
28
Words of wisdom. Re: efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma. (19051381)
2008
29
Chromophobe renal cell carcinoma in a child: case report and review of the literature. (17378685)
2007
30
Simultaneous occurrence of metastasizing carcinoid tumour of the gallbladder and chromophobe renal cell carcinoma in a young man. (18330096)
2007
31
Chromophobe renal cell carcinoma with osseous metaplasia containing fatty bone marrow element: a case report. (17669599)
2007
32
Diagnostic value of cytokeratin 7 and parvalbumin in differentiating chromophobe renal cell carcinoma from renal oncocytoma. (16927643)
2006
33
Chromophobe renal cell carcinoma with focal papillary configuration, nuclear basaloid arrangement and stromal osseous metaplasia containing fatty bone marrow element. (15910607)
2005
34
KIT and RCC are useful in distinguishing chromophobe renal cell carcinoma from the granular variant of clear cell renal cell carcinoma. (15832088)
2005
35
Toluidine positivity in chromophobe renal cell carcinoma: use in intraoperative diagnosis. (16242003)
2005
36
Insertion (8;11) in a renal oncocytoma with multifocal transformation to chromophobe renal cell carcinoma. (16337860)
2005
37
Chromophobe renal cell carcinoma: analysis of 61 cases. (15042674)
2004
38
Immunohistochemical identification of intracytoplasmic lumens by cytokeratin typing may differentiate renal oncocytomas from chromophobe renal cell carcinomas. (14702167)
2004
39
Overexpression of KIT (CD117) in chromophobe renal cell carcinoma and renal oncocytoma. (15198361)
2004
40
Chromophobe renal cell carcinoma showing oncocytoma-like hyalinized and edematous stroma: A case report and review of the literature. (15610861)
2004
41
Review of chromophobe renal cell carcinoma with focus on clinical and pathobiological aspects. (12507296)
2003
42
Chromophobe renal cell carcinoma in a patient with the Birt-Hogg-Dube syndrome. (12352424)
2002
43
FISH analysis in chromophobe renal-cell carcinoma. (10613963)
2000
44
Ultrastructural observations on mitochondria and microvesicles in renal oncocytoma, chromophobe renal cell carcinoma, and eosinophilic variant of conventional (clear cell) renal cell carcinoma. (10976699)
2000
45
Utility of cytokeratin 7 for distinguishing chromophobe renal cell carcinoma from renal oncocytoma. (10765081)
2000
46
Fine-needle aspiration biopsy of chromophobe renal cell carcinoma and oncocytoma: comparison of cytomorphologic features. (10385448)
1999
47
Discriminant nuclear features of renal oncocytoma and chromophobe renal cell carcinoma. Analysis of their potential utility in the differential diagnosis. (9844591)
1998
48
A case of chromophobe renal cell carcinoma with sarcomatoid foci and a small daughter lesion. (9788266)
1998
49
Chromophobe renal cell carcinoma: clinicopathological study of 7 cases. (9491212)
1998
50
Aggressive variants of chromophobe renal cell carcinoma. (8859189)
1996

Variations for Chromophobe Renal Cell Carcinoma

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Expression for genes affiliated with Chromophobe Renal Cell Carcinoma

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LifeMap Discovery
Genes differentially expressed in tissues of Chromophobe Renal Cell Carcinoma patients vs. healthy controls: 31 (show all 325)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1SLC12A1solute carrier family 12 (sodium/potassium/chloride transporter), member 1Kidney-10.960.000
2NAT8N-acetyltransferase 8 (GCN5-related, putative)Kidney-9.850.000
3CALB1calbindin 1, 28kDaKidney-9.440.000
4GLYATglycine-N-acyltransferaseKidney-9.240.000
5KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16Kidney-9.210.000
6FABP1fatty acid binding protein 1, liverKidney-8.950.000
7MIOXmyo-inositol oxygenaseKidney-8.890.000
8PLGplasminogenKidney-8.670.000
9NPHS2nephrosis 2, idiopathic, steroid-resistant (podocin)Kidney-8.340.000
10CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)Kidney+8.220.000
11G6PCglucose-6-phosphatase, catalytic subunitKidney-8.140.000
12SLC16A9solute carrier family 16, member 9Kidney-8.050.000
13ACMSDaminocarboxymuconate semialdehyde decarboxylaseKidney-8.040.000
14ALDOBaldolase B, fructose-bisphosphateKidney-8.030.000
15GSTA1glutathione S-transferase alpha 1Kidney-8.010.000
16SCNN1Gsodium channel, non-voltage-gated 1, gamma subunitKidney-7.850.000
17HS6ST2heparan sulfate 6-O-sulfotransferase 2Kidney-7.840.000
18PDZK1IP1PDZK1 interacting protein 1Kidney-7.830.000
19TSPAN8tetraspanin 8Kidney-7.820.000
20BHMTbetaine--homocysteine S-methyltransferaseKidney-7.750.000
21FMO1flavin containing monooxygenase 1Kidney-7.570.000
22BBOX1butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1Kidney-7.570.000
23DZIP1DAZ interacting zinc finger protein 1Kidney-7.560.000
24RNF128ring finger protein 128, E3 ubiquitin protein ligaseKidney-7.530.000
25ANPEPalanyl (membrane) aminopeptidaseKidney-7.510.000
26MUC15mucin 15, cell surface associatedKidney-7.450.000
27AGXT2alanine--glyoxylate aminotransferase 2Kidney-7.430.000
28ALDH8A1aldehyde dehydrogenase 8 family, member A1Kidney-7.360.000
29SOSTDC1sclerostin domain containing 1Kidney-7.310.000
30SLC7A13solute carrier family 7 (anionic amino acid transporter), member 13Kidney-7.310.000
31FAM151Afamily with sequence similarity 151, member AKidney-7.260.000
32TOXthymocyte selection-associated high mobility group boxKidney-7.230.000
33SLC22A8solute carrier family 22 (organic anion transporter), member 8Kidney-7.200.000
34DHRS2dehydrogenase/reductase (SDR family) member 2Kidney+7.180.000
35UGT2A3UDP glucuronosyltransferase 2 family, polypeptide A3Kidney-7.130.002
36TYRP1tyrosinase-related protein 1Kidney-7.110.000
37GPC5glypican 5Kidney-7.100.000
38PDZK1PDZ domain containing 1Kidney-7.090.002
39KRT19keratin 19Kidney-7.030.000
40FGFR3fibroblast growth factor receptor 3Kidney-7.020.000
41CLIC5chloride intracellular channel 5Kidney-7.020.001
42SLC6A13solute carrier family 6 (neurotransmitter transporter), member 13Kidney-6.970.000
43CYP4A11cytochrome P450, family 4, subfamily A, polypeptide 11Kidney-6.900.000
44CYP4A22cytochrome P450, family 4, subfamily A, polypeptide 22Kidney-6.890.000
45SLC22A2solute carrier family 22 (organic cation transporter), member 2Kidney-6.890.000
46GLYATL1glycine-N-acyltransferase-like 1Kidney-6.890.000
47GBA3glucosidase, beta, acid 3Kidney-6.880.000
48UPB1ureidopropionase, betaKidney-6.880.000
49LUMlumicanKidney-6.880.000
50NTRK2neurotrophic tyrosine kinase, receptor, type 2Kidney-6.820.000
51SLC2A2solute carrier family 2 (facilitated glucose transporter), member 2Kidney-6.810.000
52MMEmembrane metallo-endopeptidaseKidney-6.760.000
53SLC13A3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3Kidney-6.740.000
54IRX2iroquois homeobox 2Kidney-6.730.000
55TMC5transmembrane channel-like 5Kidney+6.720.001
56GCgroup-specific component (vitamin D binding protein)Kidney-6.700.000
57C2orf40chromosome 2 open reading frame 40Kidney-6.630.001
58CXCL14chemokine (C-X-C motif) ligand 14Kidney-6.620.014
59KLK15kallikrein-related peptidase 15Kidney+6.620.000
60SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19Kidney-6.610.000
61HAO2hydroxyacid oxidase 2 (long chain)Kidney-6.570.000
62MFSD4major facilitator superfamily domain containing 4Kidney-6.550.001
63CACNA2D1calcium channel, voltage-dependent, alpha 2/delta subunit 1Kidney-6.540.000
64FLRT3fibronectin leucine rich transmembrane protein 3Kidney-6.530.000
65RALYLRALY RNA binding protein-likeKidney-6.510.000
66NPY1Rneuropeptide Y receptor Y1Kidney-6.510.000
67PAHphenylalanine hydroxylaseKidney-6.500.005
68CLDN10claudin 10Kidney-6.470.001
69MGST1microsomal glutathione S-transferase 1Kidney-6.460.000
70CYP4F3cytochrome P450, family 4, subfamily F, polypeptide 3Kidney-6.460.000
71C1Scomplement component 1, s subcomponentKidney-6.430.000
72KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1Kidney-6.410.000
73MYH11myosin, heavy chain 11, smooth muscleKidney-6.400.000
74MAOBmonoamine oxidase BKidney-6.400.001
75CYS1cystin 1Kidney-6.390.028
76CAPN3calpain 3, (p94)Kidney-6.370.000
77DCNdecorinKidney-6.360.000
78GPM6Bglycoprotein M6BKidney-6.350.000
79ASS1argininosuccinate synthase 1Kidney-6.350.000
80KLklothoKidney-6.340.000
81SFRP1secreted frizzled-related protein 1Kidney-6.330.000
82SLC16A4solute carrier family 16, member 4Kidney-6.320.000
83RBP4retinol binding protein 4, plasmaKidney-6.290.000
84SLC47A1solute carrier family 47 (multidrug and toxin extrusion), member 1Kidney-6.280.000
85KNG1kininogen 1Kidney-6.270.002
86GLIS3GLIS family zinc finger 3Kidney-6.270.000
87DDCdopa decarboxylase (aromatic L-amino acid decarboxylase)Kidney-6.260.000
88ADH1Balcohol dehydrogenase 1B (class I), beta polypeptideKidney-6.260.000
89PAPPApregnancy-associated plasma protein A, pappalysin 1Kidney-6.250.000
90PLNphospholambanKidney-6.250.000
91FLJ22763uncharacterized LOC401081Kidney-6.240.000
92XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-boundKidney-6.190.000
93ABCA8ATP-binding cassette, sub-family A (ABC1), member 8Kidney-6.180.001
94CLRN3clarin 3Kidney-6.170.000
95ACOX2acyl-CoA oxidase 2, branched chainKidney-6.160.002
96WNK4WNK lysine deficient protein kinase 4Kidney-6.150.000
97HPD4-hydroxyphenylpyruvate dioxygenaseKidney-6.150.006
98DPYSdihydropyrimidinaseKidney-6.150.000
99AKAP12A kinase (PRKA) anchor protein 12Kidney-6.140.000
100HNF4Ahepatocyte nuclear factor 4, alphaKidney-6.120.000
101DIO1deiodinase, iodothyronine, type IKidney-6.090.000
102C7complement component 7Kidney-6.050.001
103AQP4aquaporin 4Kidney-6.050.001
104CDHR5cadherin-related family member 5Kidney-6.040.000
105AQP2aquaporin 2 (collecting duct)Kidney-6.040.000
106UGT2B28UDP glucuronosyltransferase 2 family, polypeptide B28Kidney-6.030.000
107LRRC19leucine rich repeat containing 19Kidney-5.990.004
108SLC22A6solute carrier family 22 (organic anion transporter), member 6Kidney-5.990.000
109AK4adenylate kinase 4Kidney-5.950.000
110LGALS2lectin, galactoside-binding, soluble, 2Kidney-5.920.000
111CXCL12chemokine (C-X-C motif) ligand 12Kidney-5.910.000
112ST8SIA5ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5Kidney+5.880.000
113PCK1phosphoenolpyruvate carboxykinase 1 (soluble)Kidney-5.880.004
114PPP1R1Aprotein phosphatase 1, regulatory (inhibitor) subunit 1AKidney-5.880.005
115CRHBPcorticotropin releasing hormone binding proteinKidney-5.870.000
116PTGDSprostaglandin D2 synthase 21kDa (brain)Kidney-5.870.000
117CFIcomplement factor IKidney-5.870.003
118HRGhistidine-rich glycoproteinKidney-5.860.000
119SMTNL2smoothelin-like 2Kidney-5.850.000
120AFF3AF4/FMR2 family, member 3Kidney-5.850.000
121LSAMPlimbic system-associated membrane proteinKidney+5.850.000
122CRYAAcrystallin, alpha AKidney-5.830.000
123KCNJ10potassium inwardly-rectifying channel, subfamily J, member 10Kidney-5.820.000
124SOSTsclerostinKidney-5.790.000
125FBLN5fibulin 5Kidney-5.770.000
126SLC13A1solute carrier family 13 (sodium/sulfate symporter), member 1Kidney-5.760.001
127CTGFconnective tissue growth factorKidney-5.760.000
128ENPEPglutamyl aminopeptidase (aminopeptidase A)Kidney-5.740.000
129ACSM2Aacyl-CoA synthetase medium-chain family member 2AKidney-5.730.000
130TPRG1tumor protein p63 regulated 1Kidney+5.720.030
131GLDCglycine dehydrogenase (decarboxylating)Kidney-5.710.000
132FOXC1forkhead box C1Kidney-5.700.002
133SLC5A12solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12Kidney-5.690.000
134IL17RBinterleukin 17 receptor BKidney-5.690.000
135COL4A5collagen, type IV, alpha 5Kidney-5.680.000
136GALNT14polypeptide N-acetylgalactosaminyltransferase 14Kidney-5.670.000
137SHMT1serine hydroxymethyltransferase 1 (soluble)Kidney-5.670.000
138CASRcalcium-sensing receptorKidney-5.660.001
139TMEM45Btransmembrane protein 45BKidney-5.650.040
140UPP2uridine phosphorylase 2Kidney-5.640.000
141LINC00588long intergenic non-protein coding RNA 588Kidney+5.630.002
142APOC1apolipoprotein C-IKidney+5.630.000
143FHL1four and a half LIM domains 1Kidney-5.620.000
144GDAguanine deaminaseKidney-5.620.001
145LRP2low density lipoprotein receptor-related protein 2Kidney-5.610.000
146SLC12A3solute carrier family 12 (sodium/chloride transporter), member 3Kidney-5.590.000
147UMODuromodulinKidney-5.590.000
148RBMS3RNA binding motif, single stranded interacting protein 3Kidney-5.590.001
149TRIM6tripartite motif containing 6Kidney-5.590.002
150TFPItissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)Kidney-5.580.000
151UGT3A1UDP glycosyltransferase 3 family, polypeptide A1Kidney-5.580.000
152DYNLRB2dynein, light chain, roadblock-type 2Kidney-5.580.000
153SLC22A3solute carrier family 22 (organic cation transporter), member 3Kidney-5.570.000
154ACE2angiotensin I converting enzyme 2Kidney-5.560.001
155DPEP1dipeptidase 1 (renal)Kidney-5.560.000
156MTTPmicrosomal triglyceride transfer proteinKidney-5.540.000
157CAPN6calpain 6Kidney-5.540.003
158AQP1aquaporin 1 (Colton blood group)Kidney-5.540.000
159ALBalbuminKidney-5.540.000
160ASPAaspartoacylaseKidney-5.520.001
161CYR61cysteine-rich, angiogenic inducer, 61Kidney-5.520.000
162ABCC6ATP-binding cassette, sub-family C (CFTR/MRP), member 6Kidney-5.520.001
163NR1H4nuclear receptor subfamily 1, group H, member 4Kidney-5.520.000
164FERMT1fermitin family member 1Kidney-5.510.002
165SYNPO2synaptopodin 2Kidney-5.500.000
166NRXN3neurexin 3Kidney+5.480.000
167CTXN3cortexin 3Kidney-5.480.000
168ENPP6ectonucleotide pyrophosphatase/phosphodiesterase 6Kidney-5.480.000
169FTCDformimidoyltransferase cyclodeaminaseKidney-5.450.000
170SLC5A10solute carrier family 5 (sodium/sugar cotransporter), member 10Kidney-5.450.000
171FOSBFBJ murine osteosarcoma viral oncogene homolog BKidney-5.440.000
172FBLN1fibulin 1Kidney-5.420.000
173SYNGR3synaptogyrin 3Kidney+5.340.000
174STXBP6syntaxin binding protein 6 (amisyn)Kidney+5.250.004
175CLNKcytokine-dependent hematopoietic cell linkerKidney+5.130.000
176TMPRSS11Etransmembrane protease, serine 11EKidney+5.120.002
177LRRC31leucine rich repeat containing 31Kidney+4.940.001
178AKR1C2aldo-keto reductase family 1, member C2Kidney+4.850.009
179CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)Kidney+4.710.015
180CTNNA2catenin (cadherin-associated protein), alpha 2Kidney+4.680.002
181KLK4kallikrein-related peptidase 4Kidney+4.640.004
182ADCY1adenylate cyclase 1 (brain)Kidney+4.460.006
183SPINK7serine peptidase inhibitor, Kazal type 7 (putative)Kidney+4.380.001
184CHRM1cholinergic receptor, muscarinic 1Kidney+4.370.037
185WBSCR17Williams-Beuren syndrome chromosome region 17Kidney+4.360.001
186HS6ST3heparan sulfate 6-O-sulfotransferase 3Kidney+4.360.001
187BCANbrevicanKidney+4.360.001
188SSTsomatostatinKidney+4.330.037
189ABHD11abhydrolase domain containing 11Kidney+4.300.003
190DOCK10dedicator of cytokinesis 10Kidney+4.150.000
191CNTNAP5contactin associated protein-like 5Kidney+4.150.001
192HTRA4HtrA serine peptidase 4Kidney+4.130.009
193RGS4regulator of G-protein signaling 4Kidney+4.120.009
194TSPAN5tetraspanin 5Kidney+4.120.002
195MARCH11membrane-associated ring finger (C3HC4) 11Kidney+4.080.021
196ANO4anoctamin 4Kidney+4.060.019
197SMOC1SPARC related modular calcium binding 1Kidney+3.980.019
198KCNG1potassium voltage-gated channel, subfamily G, member 1Kidney+3.970.002
199CCDC34coiled-coil domain containing 34Kidney+3.970.000
200NRG2neuregulin 2Kidney+3.970.024
201TMEM255Atransmembrane protein 255AKidney+3.960.048
202MFSD7major facilitator superfamily domain containing 7Kidney+3.950.006
203RHCGRh family, C glycoproteinKidney+3.940.000
204LOC100289026putative uncharacterized protein FLJ00310-likeKidney+3.930.036
205KLK3kallikrein-related peptidase 3Kidney+3.920.001
206ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)Kidney+3.900.009
207PSG3pregnancy specific beta-1-glycoprotein 3Kidney+3.900.003
208SDCBP2syndecan binding protein (syntenin) 2Kidney+3.890.000
209PCGF3polycomb group ring finger 3Kidney+3.890.001
210STAP1signal transducing adaptor family member 1Kidney+3.870.000
211SAMD4Asterile alpha motif domain containing 4AKidney+3.870.000
212DMRT2doublesex and mab-3 related transcription factor 2Kidney+3.860.000
213LOC157740uncharacterized protein C8orf9Kidney+3.840.009
214CR1Lcomplement component (3b/4b) receptor 1-likeKidney+3.810.000
215SFTPBsurfactant protein BKidney+3.790.027
216PVALBparvalbuminKidney+3.760.000
217PLEK2pleckstrin 2Kidney+3.740.001
218ADAM2ADAM metallopeptidase domain 2Kidney+3.730.000
219CDAcytidine deaminaseKidney+3.710.015
220TMEM38Atransmembrane protein 38AKidney+3.700.005
221FOXI1forkhead box I1Kidney+3.680.000
222GPSM2G-protein signaling modulator 2Kidney+3.680.021
223HIST1H2AGhistone cluster 1, H2agKidney+3.680.038
224HEPACAM2HEPACAM family member 2Kidney+3.670.000
225LOC441052uncharacterized LOC441052Kidney+3.660.009
226HHATLhedgehog acyltransferase-likeKidney+3.660.031
227PARVBparvin, betaKidney+3.660.001
228KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologKidney+3.640.000
229BAALCbrain and acute leukemia, cytoplasmicKidney+3.630.003
230PSD3pleckstrin and Sec7 domain containing 3Kidney+3.610.002
231ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2Kidney+3.610.001
232MARCH1membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligaseKidney+3.610.023
233CREB3L1cAMP responsive element binding protein 3-like 1Kidney+3.610.001
234NINJ2ninjurin 2Kidney+3.590.033
235USP7ubiquitin specific peptidase 7 (herpes virus-associated)Kidney+3.580.034
236NTN1netrin 1Kidney+3.540.004
237BCAS4breast carcinoma amplified sequence 4Kidney+3.540.018
238MIB1mindbomb E3 ubiquitin protein ligase 1Kidney+3.510.004
239OLIG1oligodendrocyte transcription factor 1Kidney+3.500.004
240ACSBG1acyl-CoA synthetase bubblegum family member 1Kidney+3.490.001
241SLC17A4solute carrier family 17, member 4Kidney+3.480.022
242PLA2G7phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)Kidney+3.470.004
243NRIP3nuclear receptor interacting protein 3Kidney+3.460.008
244ERP27endoplasmic reticulum protein 27Kidney+3.450.000
245C1orf53chromosome 1 open reading frame 53Kidney+3.450.040
246EBF2early B-cell factor 2Kidney+3.440.020
247TGFBRAP1transforming growth factor, beta receptor associated protein 1Kidney+3.430.001
248NKX2-3NK2 homeobox 3Kidney+3.420.023
249ARSJarylsulfatase family, member JKidney+3.420.000
250MTFR1mitochondrial fission regulator 1Kidney+3.410.000
251MUC20mucin 20, cell surface associatedKidney+3.400.005
252SLC9A2solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2Kidney+3.390.012
253SLIT2slit homolog 2 (Drosophila)Kidney+3.380.005
254PSG9pregnancy specific beta-1-glycoprotein 9Kidney+3.360.001
255UBE2QL1ubiquitin-conjugating enzyme E2Q family-like 1Kidney+3.330.000
256LOC441666zinc finger protein 91 pseudogeneKidney+3.320.048
257TREM2triggering receptor expressed on myeloid cells 2Kidney+3.320.001
258ZBTB43zinc finger and BTB domain containing 43Kidney+3.310.007
259TMPRSS15transmembrane protease, serine 15Kidney+3.300.010
260SPSB4splA/ryanodine receptor domain and SOCS box containing 4Kidney+3.290.000
261SYT17synaptotagmin XVIIKidney+3.290.001
262CYP11A1cytochrome P450, family 11, subfamily A, polypeptide 1Kidney+3.280.022
263FNDC5fibronectin type III domain containing 5Kidney+3.280.035
264PKIBprotein kinase (cAMP-dependent, catalytic) inhibitor betaKidney+3.280.042
265GINS2GINS complex subunit 2 (Psf2 homolog)Kidney+3.280.007
266ATP2B2ATPase, Ca++ transporting, plasma membrane 2Kidney+3.280.013
267IGF2BP3insulin-like growth factor 2 mRNA binding protein 3Kidney+3.250.002
268MAGIXMAGI family member, X-linkedKidney+3.240.001
269HCRThypocretin (orexin) neuropeptide precursorKidney+3.230.003
270SOCS1suppressor of cytokine signaling 1Kidney+3.230.000
271MTSS1metastasis suppressor 1Kidney+3.210.047
272BTG3BTG family, member 3Kidney+3.200.016
273OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEFKidney+3.190.018
274BAIAP2L1BAI1-associated protein 2-like 1Kidney+3.170.009
275VSIG10LV-set and immunoglobulin domain containing 10 likeKidney+3.170.016
276APOBEC3Bapolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3BKidney+3.160.000
277OTUD7AOTU deubiquitinase 7AKidney+3.160.008
278GAB2GRB2-associated binding protein 2Kidney+3.150.010
279TIMD4T-cell immunoglobulin and mucin domain containing 4Kidney+3.140.007
280GLDNgliomedinKidney+3.130.041
281HIST3H2Ahistone cluster 3, H2aKidney+3.130.000
282DDX28DEAD (Asp-Glu-Ala-Asp) box polypeptide 28Kidney+3.110.018
283NOP14-AS1NOP14 antisense RNA 1Kidney+3.110.014
284C7orf57chromosome 7 open reading frame 57Kidney+3.100.014
285KLRD1killer cell lectin-like receptor subfamily D, member 1Kidney+3.100.015
286DNASE1deoxyribonuclease IKidney+3.090.016
287NPTXRneuronal pentraxin receptorKidney+3.080.005
288RP11-280O1.2uncharacterized LOC400794Kidney+3.080.004
289PGBD4piggyBac transposable element derived 4Kidney+3.070.017
290PLCG2phospholipase C, gamma 2 (phosphatidylinositol-specific)Kidney+3.070.003
291KRTAP9-3keratin associated protein 9-3Kidney+3.050.033
292IL18interleukin 18 (interferon-gamma-inducing factor)Kidney+3.040.001
293DRAXINdorsal inhibitory axon guidance proteinKidney+3.030.032
294RARRES3retinoic acid receptor responder (tazarotene induced) 3Kidney+3.030.007
295FAM228Afamily with sequence similarity 228, member AKidney+3.030.034
296ELAVL2ELAV like neuron-specific RNA binding protein 2Kidney+3.000.034
297KIAA1324KIAA1324Kidney+3.000.009
298CPXM2carboxypeptidase X (M14 family), member 2Kidney+3.000.008
299TNFRSF10Ctumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domainKidney+2.990.018
300RBMY3APRNA binding motif protein, Y-linked, family 3, member A pseudogeneKidney+2.980.001
301TRBV27T cell receptor beta variable 27Kidney+2.980.028
302SALL4spalt-like transcription factor 4Kidney+2.970.007
303ANKRD29ankyrin repeat domain 29Kidney+2.970.002
304IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)Kidney+2.960.019
305HS3ST2heparan sulfate (glucosamine) 3-O-sulfotransferase 2Kidney+2.960.032
306TRPC3transient receptor potential cation channel, subfamily C, member 3Kidney+2.960.041
307GOLT1Agolgi transport 1AKidney+2.960.001
308TAGAPT-cell activation RhoGTPase activating proteinKidney+2.960.007
309SYTL5synaptotagmin-like 5Kidney+2.930.045
310CDKN2Acyclin-dependent kinase inhibitor 2AKidney+2.930.014
311HCN2hyperpolarization activated cyclic nucleotide-gated potassium channel 2Kidney+2.930.009
312HAGHLhydroxyacylglutathione hydrolase-likeKidney+2.930.002
313ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)Kidney+2.930.004
314TCF7transcription factor 7 (T-cell specific, HMG-box)Kidney+2.920.038
315LOC646903uncharacterized LOC646903Kidney+2.920.006
316SPG7spastic paraplegia 7 (pure and complicated autosomal recessive)Kidney+2.920.022
317FAHfumarylacetoacetate hydrolase (fumarylacetoacetase)Kidney+2.920.001
318MUC7mucin 7, secretedKidney+2.910.016
319SLC38A10solute carrier family 38, member 10Kidney+2.910.014
320PHLDA1pleckstrin homology-like domain, family A, member 1Kidney+2.910.021
321CYTIPcytohesin 1 interacting proteinKidney+2.910.000
322PDP1pyruvate dehyrogenase phosphatase catalytic subunit 1Kidney+2.910.001
323GPNMBglycoprotein (transmembrane) nmbKidney+2.900.006
324MTUS2microtubule associated tumor suppressor candidate 2Kidney+2.900.010
325BAALCOSBAALC opposite strandKidney+2.880.001

Expression patterns in normal tissues for genes affiliated with Chromophobe Renal Cell Carcinoma

Search GEO for disease gene expression data for Chromophobe Renal Cell Carcinoma.

Pathways for genes affiliated with Chromophobe Renal Cell Carcinoma

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Pathways related to Chromophobe Renal Cell Carcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6CDH16, PSMB9
29.6CDH16, PSMB9

Compounds for genes affiliated with Chromophobe Renal Cell Carcinoma

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Sources:
44Novoseek, 12DrugBank
See all sources

Compounds related to Chromophobe Renal Cell Carcinoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1aprotinin44 1210.5PRSS8, MME

GO Terms for genes affiliated with Chromophobe Renal Cell Carcinoma

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Cellular components related to Chromophobe Renal Cell Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1plasma membraneGO:0058867.7CDH16, PRSS8, MME, FLCN, CLDN8

Biological processes related to Chromophobe Renal Cell Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1kidney developmentGO:0018229.4HNF1B, MME

Products for genes affiliated with Chromophobe Renal Cell Carcinoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Chromophobe Renal Cell Carcinoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet