CEBV
MCID: CHR276
MIFTS: 44

Chronic Active Epstein-Barr Virus Infection (CEBV) malady

Categories: Rare diseases

Aliases & Classifications for Chronic Active Epstein-Barr Virus Infection

Aliases & Descriptions for Chronic Active Epstein-Barr Virus Infection:

Name: Chronic Active Epstein-Barr Virus Infection 50
Chronic Active Epstein-Barr Disease 50
Caebv Infection 50
Cebv 50

Classifications:



Summaries for Chronic Active Epstein-Barr Virus Infection

NIH Rare Diseases : 50 chronic active epstein-barr virus infection is a rare condition in which the body makes too many lymphocytes, a type of white blood cell. lymphocytes are an important part of the immune system because they help fight off diseases and protect the body from infection. about 95% of adults are infected with epstein-barr virus (ebv). most infections occur during childhood and do not cause any symptoms. ebv infection in adolescents or young adults can often result in infectious mononucleosis.  rarely, people infected with ebv develop a life-threatening condition called chronic active ebv virus (caebv). patients with caebv most often have fever, liver dysfunction, an enlarged spleen (splenomegaly), swollen lymph nodes (lymphadenopathy), and low numbers of platelets (thrombocytopenia). hematopoietic stem cell transplantation has shown promise in the treatment of caebv. last updated: 5/11/2015

MalaCards based summary : Chronic Active Epstein-Barr Virus Infection, also known as chronic active epstein-barr disease, is related to hepatitis and rheumatoid arthritis. An important gene associated with Chronic Active Epstein-Barr Virus Infection is LAIR1 (Leukocyte Associated Immunoglobulin Like Receptor 1), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Allograft rejection. The drugs rituximab and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include liver, spleen and t cells, and related phenotypes are hematopoietic system and cardiovascular system

Related Diseases for Chronic Active Epstein-Barr Virus Infection

Diseases related to Chronic Active Epstein-Barr Virus Infection via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 123)
id Related Disease Score Top Affiliating Genes
1 hepatitis 30.4 CTLA4 IFNG IL10 IL2
2 rheumatoid arthritis 29.4 CTLA4 IFNG IL10 IL2 TGFB1 TNFAIP6
3 lymphoma 10.4
4 refractory celiac disease 10.3 IL10 TGFB1
5 paralytic poliomyelitis 10.2 IFNG IL2
6 caplan's syndrome 10.2 IFNG IL2
7 asymptomatic neurosyphilis 10.2 IFNG IL10
8 strawberry gallbladder 10.2 IFNG IL2 TGFB1
9 autosomal dominant deafness-onychodystrophy syndrome 10.2 IFNG IL2
10 severe combined immunodeficiency, t cell-negative, b-cell/natural killer-cell positive 10.2 IFNG IL10 IL2
11 cyclosporiasis 10.2 IFNG IL10 IL2
12 tularemia 10.2 IFNG IL10 IL2
13 acute myeloid leukemia with recurrent genetic anomaly 10.2 IFNG IL10 IL2
14 microcephaly 10.2 IFNG IL10 IL2
15 oropharynx cancer 10.2 IFNG IL10 IL2
16 orbital osteomyelitis 10.2 IFNG IL10 IL2
17 heart conduction disease 10.2 IFNG IL10 IL2
18 causalgia 10.2 IFNG IL10 IL2
19 dengue hemorrhagic fever 10.2 IFNG IL10 IL2
20 anterior foramen magnum meningioma 10.2 IFNG IL10 IL2
21 discharging ear 10.2 IFNG IL10 TGFB1
22 blue toe syndrome 10.2 IFNG IL10 IL2
23 janus kinase-3 deficiency 10.2 CTLA4 IFNG IL2
24 papillary adenocarcinoma 10.2 IL10 TGFB1
25 rosacea 10.2 IFNG IL10 SELE
26 nonspecific interstitial pneumonia 10.2 IFNG IL10 IL2
27 periodontosis 10.2 CTLA4 IFNG IL2
28 autoimmune hemolytic anemia 10.2 CTLA4 IFNG IL2
29 loiasis 10.2 IFNG IL10 TGFB1
30 erb-duchenne and dejerine-klumpke palsies 10.2 IFNG IL10 SELE
31 burns 10.2 IFNG IL10 TGFB1
32 uterus interstitial leiomyoma 10.2 IFNG IL10 IL2
33 lichen disease 10.2 IL10 IL2 TGFB1
34 foodborne botulism 10.2 IFNG IL10 IL2
35 de quervain disease 10.2 IL2 SELE THBD
36 balkan nephropathy 10.1 IFNG IL10 SELE
37 hematopoietic stem cell transplantation 10.1
38 hydroa vacciniforme 10.1
39 autoimmune hepatitis 10.1
40 aneurysm 10.1
41 multiple carboxylase deficiency 10.1 CTLA4 IFNG IL2
42 anus leiomyosarcoma 10.1 IFNG IL10 IL2
43 parasitic protozoa infectious disease 10.1 IFNG IL10 SELE
44 testicular lymphoma 10.1 IFNG SELE TGFB1
45 sclerosing adenosis of breast 10.1 IFNG IL10 TGFB1
46 keratomalacia 10.1 IDO1 IFNG IL10
47 periarthritis 10.1 IFNG IL10 IL2
48 geniculate ganglionitis 10.1 IFNG IL10 SELE
49 scleral disease 10.1 IFNG IL10 IL2
50 denys-drash syndrome 10.1 CTLA4 IFNG IL10

Graphical network of the top 20 diseases related to Chronic Active Epstein-Barr Virus Infection:



Diseases related to Chronic Active Epstein-Barr Virus Infection

Symptoms & Phenotypes for Chronic Active Epstein-Barr Virus Infection

MGI Mouse Phenotypes related to Chronic Active Epstein-Barr Virus Infection:

44 (show all 11)
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.17 ATR CTLA4 GBP5 IDO1 IFNG IL10
2 cardiovascular system MP:0005385 10.15 IL2 SELE TGFB1 THBD ATR CTLA4
3 immune system MP:0005387 10.15 ATR CTLA4 GBP5 IDO1 IFNG IL10
4 homeostasis/metabolism MP:0005376 10.1 CTLA4 GBP5 IDO1 IFNG IL10 IL2
5 endocrine/exocrine gland MP:0005379 10.06 ATR CTLA4 IFNG IL10 IL2 LAIR1
6 digestive/alimentary MP:0005381 10.02 ATR CTLA4 IFNG IL10 IL2 TGFB1
7 integument MP:0010771 9.87 ATR CTLA4 IFNG IL10 SELE TGFB1
8 liver/biliary system MP:0005370 9.86 ATR CTLA4 IFNG IL10 IL2 SELE
9 normal MP:0002873 9.7 ATR CTLA4 IFNG IL10 LAIR1 SELE
10 reproductive system MP:0005389 9.56 ATR IDO1 IFNG IL10 IL2 TGFB1
11 respiratory system MP:0005388 9.28 SELE TGFB1 THBD TNFAIP6 ATR CTLA4

Drugs & Therapeutics for Chronic Active Epstein-Barr Virus Infection

Drugs for Chronic Active Epstein-Barr Virus Infection (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 109)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
rituximab Approved Phase 3,Phase 1,Phase 2 174722-31-7 10201696
2
Prednisone Approved, Vet_approved Phase 3,Phase 2 53-03-2 5865
3
Doxorubicin Approved, Investigational Phase 3,Phase 2 23214-92-8 31703
4
Vincristine Approved, Investigational Phase 3,Phase 2 2068-78-2, 57-22-7 5978
5
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
6
Lenalidomide Approved Phase 3,Phase 2 191732-72-6 216326
7
Hydroxyurea Approved Phase 2, Phase 3 127-07-1 3657
8
Doxil Approved June 1999 Phase 3,Phase 2 31703
9 Topoisomerase Inhibitors Phase 3,Phase 2
10 Anti-Infective Agents Phase 3,Phase 2,Phase 1
11 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
12 Antirheumatic Agents Phase 3,Phase 1,Phase 2
13 glucocorticoids Phase 3,Phase 2
14 Nucleic Acid Synthesis Inhibitors Phase 2, Phase 3
15 Hormone Antagonists Phase 3,Phase 2
16 Hormones Phase 3,Phase 2
17 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2
18 Anti-Bacterial Agents Phase 3,Phase 2
19 Anti-Inflammatory Agents Phase 3,Phase 2
20 Antibiotics, Antitubercular Phase 3,Phase 2
21 Alkylating Agents Phase 3,Phase 2,Phase 1
22 Angiogenesis Inhibitors Phase 3,Phase 2
23 Angiogenesis Modulating Agents Phase 3,Phase 2
24 Antimitotic Agents Phase 3,Phase 2
25 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1
26 Antineoplastic Agents, Hormonal Phase 3,Phase 2
27 Antineoplastic Agents, Phytogenic Phase 3,Phase 2
28
Mitoxantrone Approved, Investigational Phase 2 65271-80-9 4212
29
Cytarabine Approved, Investigational Phase 2 147-94-4 6253
30
Lenograstim Approved Phase 2 135968-09-1
31
Cladribine Approved, Investigational Phase 2 4291-63-8 20279
32
Cyclosporine Approved, Investigational, Vet_approved Phase 2 79217-60-0, 59865-13-3 5284373 6435893
33
Tacrolimus Approved, Investigational Phase 2 104987-11-3 445643 439492
34
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
35
Mycophenolic acid Approved Phase 2 24280-93-1 446541
36
Mycophenolate mofetil Approved, Investigational Phase 2 128794-94-5 5281078
37
Pentostatin Approved, Investigational Phase 2 53910-25-1 40926 439693
38
Etanercept Approved, Investigational Phase 2 185243-69-0
39
Adenosine Approved, Investigational Phase 2 58-61-7 60961
40
Denileukin diftitox Approved, Investigational Phase 2 173146-27-5
41
Tofacitinib Approved, Investigational Phase 2 477600-75-2
42
Acetaminophen Approved Phase 2 103-90-2 1983
43
Fludarabine Approved Phase 2,Phase 1 21679-14-1, 75607-67-9 30751
44
Allopurinol Approved Phase 2 315-30-0 2094
45
Prednisolone Approved, Vet_approved Phase 2 50-24-8 5755
46
Diphenhydramine Approved Phase 2 58-73-1, 147-24-0 3100
47
Benzocaine Approved Phase 2 1994-09-7, 94-09-7 2337
48
Promethazine Approved Phase 2 60-87-7 4927
49
Methylprednisolone Approved, Vet_approved Phase 2 83-43-2 6741
50
Melphalan Approved Phase 2 148-82-3 4053 460612

Interventional clinical trials:

(show all 42)
id Name Status NCT ID Phase
1 Efficacy and Safety Study of Lenalidomide Plus R-CHOP Chemotherapy Versus Placebo Plus R-CHOP Chemotherapy in Untreated ABC Type Diffuse Large B-cell Lymphoma Recruiting NCT02285062 Phase 3
2 Hydroxyurea in Primary Progressive Multiple Sclerosis Terminated NCT01103583 Phase 2, Phase 3
3 Trial of Cladribine, Cytarabine, Mitoxantrone, Filgrastim (CLAG-M) in Relapsed Acute Lymphoblastic Leukemia Unknown status NCT01513603 Phase 2
4 Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas Unknown status NCT01805037 Phase 1, Phase 2
5 Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer Completed NCT00489203 Phase 2
6 Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302) Completed NCT00224874 Phase 2
7 A 6-Month Study Of CP-690,550 Versus Tacrolimus In Kidney Transplant Patients Completed NCT00106639 Phase 2
8 Extension Study Of Stage 1 Subjects Of Study A3921009 For The Prevention Of Acute Rejection In Kidney Transplant Patient Completed NCT00263328 Phase 2
9 Study of Ibrutinib in Combination With Rituximab-CHOP in Epstein-Barr Virus-positive Diffuse Large B-cell Lymphoma Recruiting NCT02670616 Phase 2
10 Phase I/II Trial of Early Infusion of Rapidly-generated Multivirus Specific T Cells (MVST) to Prevent Post Transplant Viral Infections Recruiting NCT02231853 Phase 1, Phase 2
11 Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies Recruiting NCT01028716 Phase 2
12 Allo HSCT Using RIC for Hematological Diseases Recruiting NCT02661035 Phase 2
13 Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204) Active, not recruiting NCT01998633 Phase 2
14 Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer Active, not recruiting NCT00105001 Phase 2
15 Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas Not yet recruiting NCT03038672 Phase 2
16 Lenalidomide With or Without Rituximab in Treating Patients With Progressive or Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Prolymphocytic Leukemia, or Non-Hodgkin Lymphoma Previously Treated With Donor Stem Cell Transplant Terminated NCT01419795 Phase 2
17 Open-Label Phase 2 Trial of a Steroid-Free, CNI-Free, Belatacept-Based Immunosuppressive Regimen Terminated NCT01856257 Phase 2
18 Treating Severe Chronic Epstein-Barr Virus (EBV) Infection With EBV Specific Cytotoxic T Lymphocytes (CTLs) Completed NCT00058591 Phase 1
19 Vorinostat and Decitabine in Treating Patients With Advanced Solid Tumors or Relapsed or Refractory Non-Hodgkin's Lymphoma, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Chronic Myelogenous Leukemia Completed NCT00275080 Phase 1
20 MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia Completed NCT01231919 Phase 1
21 Bortezomib in Treating Patients With Advanced Cancer and Kidney Dysfunction Completed NCT00054483 Phase 1
22 3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma Completed NCT00293345 Phase 1
23 Most Closely Matched 3rd Party Rapidly Generated LMP, BARF1 And EBNA1 Specific CTL, EBV-Positive Lymphoma (MABEL) Recruiting NCT02287311 Phase 1
24 Cytotoxic T Cells to Treat Relapsed EBV-positive Lymphoma Recruiting NCT01956084 Phase 1
25 Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE Recruiting NCT01555892 Phase 1
26 Multivirus-specific Cytotoxic T Lymphocytes (mCTL) Recruiting NCT02510404 Phase 1
27 Study of ADCT-402 in Patients With Relapsed or Refractory B-cell Lineage Non Hodgkin Lymphoma (B-NHL) Recruiting NCT02669017 Phase 1
28 Study of ADCT-301 in Patients With Relapsed or Refractory Hodgkin and Non-Hodgkin Lymphoma Recruiting NCT02432235 Phase 1
29 CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene Active, not recruiting NCT00710892 Phase 1
30 Most Closely HLA-Matched CTLs for Relapsed Epstein Barr Virus(EBV)-Associated Diseases Active, not recruiting NCT01447056 Phase 1
31 LMP-specific T-cells for Patients With Relapsed EBV-positive Lymphoma Active, not recruiting NCT00062868 Phase 1
32 T-cells or EBV Specific CTLs, Advanced B-Cell NHL and CLL Active, not recruiting NCT00709033 Phase 1
33 Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant Active, not recruiting NCT01588015 Phase 1
34 Lmp1 and Lmp2 Specific CTLs Following Cd45 Antibody for Relapsed Ebv-Positive Hodgkin's Or Non-Hodgkin's Lymphoma Terminated NCT00383097 Phase 1
35 Chronic Presence of Epstein Barr Virus in Epithelial Cells From Gingiva is Associated With Periodontitis Unknown status NCT01246596
36 Chronic Presence of Epstein Barr Virus in Sulcular and Junctional Epithelial Tissue From Gingiva is Associated With Severe Periodontitis Unknown status NCT01246648
37 Palifermin in Preventing Chronic Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer Completed NCT01233921
38 Genomics of Kidney Transplantation Completed NCT01714440
39 Genetic Studies of Chronic Active Epstein-Barr Disease Recruiting NCT00032513
40 Mental Training for CFS Following EBV Infection in Adolescents Recruiting NCT02499302
41 Blood Sample Markers of Reproductive Hormones in Assessing Ovarian Reserve in Younger Patients With Newly Diagnosed Lymphomas Recruiting NCT01793233
42 Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer Active, not recruiting NCT01053494

Search NIH Clinical Center for Chronic Active Epstein-Barr Virus Infection

Genetic Tests for Chronic Active Epstein-Barr Virus Infection

Anatomical Context for Chronic Active Epstein-Barr Virus Infection

MalaCards organs/tissues related to Chronic Active Epstein-Barr Virus Infection:

39
Liver, Spleen, T Cells, Lymph Node, Nk Cells, Bone, Bone Marrow

Publications for Chronic Active Epstein-Barr Virus Infection

Articles related to Chronic Active Epstein-Barr Virus Infection:

(show top 50) (show all 147)
id Title Authors Year
1
Chronic active Epstein-Barr virus infection with marked pericardial effusion successfully treated with allogeneic peripheral blood stem cell transplantation. ( 27263789 )
2016
2
Successful Cord Blood Stem Cell Transplantation for an Adult Case of Chronic Active Epstein-Barr Virus Infection. ( 27904117 )
2016
3
Early relapse of severe chronic active Epstein-Barr virus infection with posterior reversible encephalopathy syndrome after reduced intensity stem cell transplantation with umbilical cord blood. ( 26879589 )
2016
4
Chronic active Epstein-Barr virus infection with cutaneous and sinus lymphoproliferation in a white female patient with 25A years' follow-up: an original case report. ( 26148205 )
2015
5
Pulmonary arterial hypertension associated with chronic active Epstein-Barr virus infection. ( 25809637 )
2015
6
Recent Concise Viewpoints of Chronic Active Epstein-Barr Virus Infection. ( 25938379 )
2015
7
Metachronous B-cell and T-cell post-transplant lymphoproliferative disorders with features of chronic active Epstein-Barr virus infection. ( 26178917 )
2015
8
Recurrence of chronic active Epstein-Barr virus infection presenting with myelopathy after umbilical cord blood transplantation. ( 25342015 )
2014
9
Possible autoimmune hepatitis induced after chronic active Epstein-Barr virus infection. ( 26183510 )
2014
10
Fatal pulmonary complications in an immunodeficient child with chronic active Epstein-Barr virus infection. ( 24964240 )
2014
11
Current research on chronic active Epstein-Barr virus infection in Japan. ( 24528553 )
2014
12
Chronic active Epstein-Barr virus infection mimicking autoimmune hepatitis exacerbation in a patient with systemic lupus erythematosus. ( 24608961 )
2014
13
Role of latent membrane protein 1 in chronic active Epstein-Barr virus infection-derived T/NK-cell proliferation. ( 24799376 )
2014
14
Chronic active Epstein-Barr virus infection complicated with multiple artery aneurysms. ( 24939943 )
2014
15
An elderly patient with chronic active Epstein-Barr virus infection with severe hydroa vacciniforme-like eruptions associated with I+I^T-cell proliferation. ( 24628134 )
2014
16
PCR array analysis of gene expression profiles in chronic active Epstein-Barr virus infection. ( 24801498 )
2014
17
Interleukin-17A-producing T lymphocytes in chronic active Epstein-Barr virus infection. ( 23252773 )
2013
18
Chronic active Epstein-Barr virus infection: a novel cause of lymphocytic variant hypereosinophilic syndrome. ( 23520331 )
2013
19
Chronic active Epstein-Barr virus infection-associated hydroa vacciniforme-like eruption and BehAset's-like orogenital ulcers. ( 23751255 )
2013
20
Chronic active Epstein-Barr virus infection with progression to large granular lymphocytic leukemia. ( 23731478 )
2013
21
An elderly patient with chronic active Epstein-Barr virus infection with mixed cryoglobulinemia and review of the literature. ( 22895834 )
2013
22
Plasma viral microRNA profiles reveal potential biomarkers for chronic active Epstein-Barr virus infection. ( 23687223 )
2013
23
Giant cell arteritis associated with chronic active Epstein-Barr virus infection. ( 23550258 )
2013
24
Epstein-Barr virus-positive cytotoxic T-cell lymphoma followed by chronic active Epstein-Barr virus infection-associated T/NK-cell lymphoproliferative disorder: a case report. ( 24012167 )
2013
25
A case of chronic active Epstein-Barr virus infection mimicking adult-onset Still's disease. ( 22370999 )
2013
26
Central nervous system complications and neuroradiological findings in children with chronic active Epstein-Barr virus infection. ( 23240920 )
2013
27
An adult case of severe chronic active Epstein-Barr virus infection with T-cell lymphoproliferative disorder. ( 23269893 )
2012
28
Recurrence of chronic active Epstein-Barr virus infection from donor cells after achieving complete response through allogeneic bone marrow transplantation. ( 22466838 )
2012
29
Quantification of Epstein-Barr virus DNA is helpful for evaluation of chronic active Epstein-Barr virus infection. ( 22850617 )
2012
30
Autoimmune lymphoproliferative syndrome mimicking chronic active Epstein-Barr virus infection. ( 21626105 )
2011
31
Aggressive large B-cell lymphoma in a systemic lupus erythematosus patient with chronic active Epstein-Barr virus infection: a case report. ( 22230415 )
2011
32
Elevated expression of activation-induced cytidine deaminase in T and NK cells from patients with chronic active Epstein-Barr virus infection. ( 21697063 )
2011
33
Pulmonary arterial hypertension associated with chronic active Epstein-Barr virus infection. ( 21245635 )
2011
34
Clinical features of adult-onset chronic active Epstein-Barr virus infection: a retrospective analysis. ( 21491104 )
2011
35
An adult case of chronic active Epstein-Barr virus infection with interstitial pneumonitis. ( 22205850 )
2011
36
Lymphomatoid granulomatosis developing from chronic active Epstein-Barr virus infection in a patient with myelodysplastic syndrome. ( 20345445 )
2010
37
A case of unilateral optic disc swelling with chronic active Epstein-Barr virus infection. ( 20856592 )
2010
38
Chronic active Epstein-Barr virus infection mimicking Henoch-SchAPnlein purpura. ( 21245820 )
2010
39
Flow cytometric analysis of skin blister fluid induced by mosquito bites in a patient with chronic active Epstein-Barr virus infection. ( 19915947 )
2009
40
Fatal degeneration of specialized cardiac muscle associated with chronic active Epstein-Barr virus infection. ( 20158631 )
2009
41
Cardiovascular complications associated with chronic active Epstein-Barr virus infection. ( 19184184 )
2009
42
M-protein-positive chronic active Epstein-Barr virus infection: features mimicking HIV-1 infection. ( 19588219 )
2009
43
Chronic active Epstein-Barr virus infection with mosquito allergy successfully treated with reduced-intensity unrelated allogeneic bone marrow transplantation in a boy. ( 18627511 )
2009
44
Clinical analysis and follow-up study of chronic active Epstein-Barr virus infection in 53 pediatric cases. ( 19236801 )
2009
45
Two cases of chronic active Epstein-Barr virus infection in which EBV-specific cytotoxic T lymphocyte was induced after allogeneic bone marrow transplantation. ( 18266798 )
2008
46
Clinical and virological characteristics of patients with chronic active Epstein-Barr virus infection treated with hematopoietic stem cell transplantation: insights and questions. ( 18419487 )
2008
47
Fatal liver failure: molecular evidence for chronic active Epstein-Barr virus infection. ( 18774502 )
2008
48
Poor outcomes of chronic active Epstein-Barr virus infection and hemophagocytic lymphohistiocytosis in non-Japanese adult patients. ( 18491961 )
2008
49
IFN-gamma mediated pathways in patients with fatigue and chronic active Epstein Barr virus-infection. ( 17945348 )
2008
50
Severe degenerative change of multiple organs mediated by chronic active Epstein-Barr virus infection with infected T-cell expansion. ( 18427908 )
2008

Variations for Chronic Active Epstein-Barr Virus Infection

Expression for Chronic Active Epstein-Barr Virus Infection

Search GEO for disease gene expression data for Chronic Active Epstein-Barr Virus Infection.

Pathways for Chronic Active Epstein-Barr Virus Infection

Pathways related to Chronic Active Epstein-Barr Virus Infection according to GeneCards Suite gene sharing:

(show all 29)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.23 GBP1 GBP5 IFNG IL10 IL2 TGFB1
2
Show member pathways
12.71 CTLA4 IFNG IL10 IL2 TGFB1
3
Show member pathways
12.46 IFNG IL10 IL2 TGFB1
4 12.39 CTLA4 IDO1 IFNG IL10 IL2
5
Show member pathways
12.18 CTLA4 IFNG IL10 IL2 TGFB1
6
Show member pathways
12.02 IFNG IL10 IL2
7 11.96 IFNG SELE THBD
8 11.88 IFNG IL2 TGFB1
9 11.85 IFNG IL10 IL2 LAIR1
10 11.79 SELE TGFB1 THBD
11 11.77 IFNG IL10 TGFB1
12 11.74 CTLA4 IFNG TGFB1
13
Show member pathways
11.73 IFNG IL10 IL2 TGFB1
14 11.69 IFNG IL2 SELE
15 11.67 IFNG IL10 IL2
16
Show member pathways
11.64 CTLA4 IFNG IL2
17 11.59 CTLA4 IL10 TGFB1
18 11.56 IFNG IL10 IL2
19 11.54 IFNG IL2 TGFB1
20
Show member pathways
11.51 IFNG IL2 SELE
21 11.38 IFNG IL2 TGFB1
22 11.36 IFNG IL10 IL2
23 11.31 IFNG IL10 SELE TGFB1
24
Show member pathways
11.16 IFNG IL10 IL2 TGFB1
25 11.08 IFNG IL2 TGFB1
26 11.02 IFNG IL10 IL2
27 11 IDO1 IFNG IL10 SELE
28 10.9 IFNG IL10 IL2 TGFB1 THBD
29 10.73 IFNG IL10 IL2 TGFB1

GO Terms for Chronic Active Epstein-Barr Virus Infection

Cellular components related to Chronic Active Epstein-Barr Virus Infection according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.17 IFNG IL10 IL2 SELE TGFB1 THBD

Biological processes related to Chronic Active Epstein-Barr Virus Infection according to GeneCards Suite gene sharing:

(show all 20)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of apoptotic process GO:0043065 9.86 CTLA4 IDO1 IFNG TGFB1
2 response to drug GO:0042493 9.85 ATR IFNG IL10 TGFB1
3 female pregnancy GO:0007565 9.69 IDO1 TGFB1 THBD
4 immune system process GO:0002376 9.63 CTLA4 GBP1 GBP5 IDO1 IL2 LAIR1
5 adaptive immune response GO:0002250 9.62 CTLA4 IFNG IL2 LAIR1
6 negative regulation of inflammatory response GO:0050728 9.61 IL10 IL2 TNFAIP6
7 defense response to protozoan GO:0042832 9.59 IFNG IL10
8 negative regulation of DNA replication GO:0008156 9.58 ATR TGFB1
9 negative regulation of growth of symbiont in host GO:0044130 9.58 IFNG IL10
10 negative regulation of B cell proliferation GO:0030889 9.57 CTLA4 IL10
11 response to lipopolysaccharide GO:0032496 9.56 IDO1 IL10 SELE THBD
12 negative regulation of immune response GO:0050777 9.54 CTLA4 TGFB1
13 positive regulation of interleukin-17 production GO:0032740 9.52 IL2 TGFB1
14 negative regulation of interleukin-17 production GO:0032700 9.49 IFNG TGFB1
15 positive regulation of regulatory T cell differentiation GO:0045591 9.48 IL2 TGFB1
16 positive regulation of isotype switching to IgG isotypes GO:0048304 9.46 IFNG IL2
17 inflammatory response GO:0006954 9.43 GBP5 IDO1 IL10 SELE TGFB1 TNFAIP6
18 positive regulation of MHC class II biosynthetic process GO:0045348 9.4 IFNG IL10
19 negative regulation of protein localization to plasma membrane GO:1903077 9.37 GBP1 TGFB1
20 negative regulation of T cell proliferation GO:0042130 8.92 CTLA4 IDO1 IL10 TGFB1

Molecular functions related to Chronic Active Epstein-Barr Virus Infection according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.92 IFNG IL10 IL2 TGFB1

Sources for Chronic Active Epstein-Barr Virus Infection

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