MCID: CHR087
MIFTS: 33

Chronic Cystitis malady

Summaries for Chronic Cystitis

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Chronic Cystitis is related to cystitis and urethritis. An important gene associated with Chronic Cystitis is PTGS1 (prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)), and among its related pathways is PIP3 activates AKT signaling. The compounds pgj-2 and camptothecin have been mentioned in the context of this disorder. Affiliated tissues include prostate, pituitary and spinal cord, and related mouse phenotype muscle.

Aliases & Classifications for Chronic Cystitis

About this section
Sources:
8Disease Ontology, 44Novoseek, 60UMLS, 27ICD9CM, 56SNOMED-CT
See all sources

Aliases & Descriptions:

chronic cystitis 8 44 60


External Ids:

Disease Ontology8 DOID:1680
ICD9CM27 595.2

Related Diseases for Chronic Cystitis

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Cystitis family:

Acute Cystitis chronic cystitis

Diseases related to Chronic Cystitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 24)
idRelated DiseaseScoreTop Affiliating Genes
1cystitis31.1NGF
2urethritis10.1
3chronic interstitial cystitis10.1
4bladder carcinoma10.1
5prostatitis10.1
6cellulitis10.0
7bladder lymphoma10.0
8vesicoureteral reflux10.0
9acute cystitis10.0
10chronic pyelonephritis10.0
11pyelonephritis10.0
12squamous cell carcinoma10.0
13urticaria10.0PTGS1
14pheochromocytoma10.0NGF
15astrocytoma10.0NGF
16osteosarcoma10.0NGF
17desmoid tumor10.0KIT
18oligodendroglioma10.0PTGS1
19polycythemia vera10.0KIT
20teratoma10.0KIT
21asthma10.0NGF, PTGS1
22factor vii deficiency10.0NGF, KIT
23glioblastoma multiforme10.0KIT, NGF
24leukemia10.0NGF, KIT, PTGS1

Graphical network of the top 20 diseases related to Chronic Cystitis:



Diseases related to chronic cystitis

Clinical Features for Chronic Cystitis

About this section

Drugs & Therapeutics for Chronic Cystitis

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Chronic Cystitis

Drug clinical trials:

Search ClinicalTrials for Chronic Cystitis

Search NIH Clinical Center for Chronic Cystitis

Search CenterWatch for Chronic Cystitis

Genetic Tests for Chronic Cystitis

About this section

Anatomical Context for Chronic Cystitis

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Chronic Cystitis:

32
Prostate, Pituitary, Spinal cord, Testes

Animal Models for Chronic Cystitis or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Chronic Cystitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.9NGF

Publications for Chronic Cystitis

About this section
Sources:
50PubMed
See all sources

Articles related to Chronic Cystitis:

(show top 50)    (show all 89)
idTitleAuthorsYear
1
Intravesical glycosaminoglycans in the management of chronic cystitis. (24091478)
2013
2
Editorial comment to interleukin-6 levels in female rats with protamine sulfate-induced chronic cystitis treated with hyaluronic acid. (23360376)
2013
3
MicroRNA-mediated GABA AI+-1 receptor subunit down-regulation in adult spinal cord following neonatal cystitis-induced chronic visceral pain in rats. (23273104)
2013
4
The prevalence and overlap of interstitial cystitis/bladder pain syndrome and chronic prostatitis/chronic pelvic pain syndrome in men: results of the RAND Interstitial Cystitis Epidemiology male study. (23164386)
2013
5
Evaluation of the impact of the urinary symptoms on quality of life of patients with painful bladder syndrome/chronic pelvic pain and radiation cystitis: EURCIS study. (24360594)
2013
6
GAG layer replenishment therapy for chronic forms of cystitis with intravesical glycosaminoglycans--a review. (22782909)
2013
7
The subject, its biology, and the chronic recurrent cystitis. (22934220)
2012
8
Reinforcements arrive for the war against chronic cystitis and bladder cancer. (22882427)
2012
9
Efficacy of sacral neuromodulation in treating chronic pain related to painful bladder syndrome/interstitial cystitis in adults. (23225919)
2012
10
Pain: Novel lidocaine delivery device for chronic interstitial cystitis. (22890300)
2012
11
Emphysematous cystitis as complication in chronic rejection of renal transplant. (21385488)
2011
12
The role of a leaky epithelium and potassium in the generation of bladder symptoms in interstitial cystitis/overactive bladder, urethral syndrome, prostatitis and gynaecological chronic pelvic pain. (21176078)
2011
13
Sequestration of brain derived nerve factor by intravenous delivery of TrkB-Ig2 reduces bladder overactivity and noxious input in animals with chronic cystitis. (20079809)
2010
14
Decreased viral load and symptoms of polyomavirus-associated chronic interstitial cystitis after intravesical cidofovir treatment. (19292661)
2009
15
Clinical phenotyping in chronic prostatitis/chronic pelvic pain syndrome and interstitial cystitis: a management strategy for urologic chronic pelvic pain syndromes. (18645581)
2009
16
Comparison of economic impact of chronic prostatitis/chronic pelvic pain syndrome and interstitial cystitis/painful bladder syndrome. (19193408)
2009
17
CD34+ fibrocytes in chronic cystitis and noninvasive and invasive urothelial carcinomas of the urinary bladder. (17149610)
2007
18
Intravesical botulinum toxin type A in chronic interstitial cystitis: results of a pilot study. (18080606)
2007
19
Intravesical vaccination against Helicobacter pylori in patients with chronic cystitis may confer protection against MALT-type lymphoma of the bladder. (17825999)
2007
20
The effect of chronic inflammatory condition of the bladder and estrogen replacement therapy on bladder functions and histology in surgically menopause and chronic cystitis induced rats. (16267856)
2006
21
Preliminary results of suburothelial injection of botulinum a toxin in the treatment of chronic interstitial cystitis. (16123573)
2005
22
Prostatitis, interstitial cystitis, chronic pelvic pain, and urethral syndrome share a common pathophysiology: lower urinary dysfunctional epithelium and potassium recycling. (14665339)
2003
23
Chronic cystitis caused by Corynebacterium urealyticum detected by polymerase chain reaction. (11205634)
2000
24
Intravesical electromotive drug administration for the treatment of non-infectious chronic cystitis. (9449584)
1997
25
Concurrent malakoplakia and primary squamous cell carcinoma arising in long-standing chronic cystitis. (7827859)
1994
26
Traditional acupuncture and electrical stimulation of the posterior tibial nerve. A trial in chronic interstitial cystitis. (8493470)
1993
27
Management of severe chronic radiation cystitis. (1416787)
1992
28
Association of chronic interstitial cystitis, protein-losing enteropathy and paralytic ileus with seronegative systemic lupus erythematosus: case report and review of the literature. (1606774)
1992
29
Vesical manifestations of chronic granulomatous disease in children. Its relation to eosinophilic cystitis. (2024396)
1991
30
Loss of blood group ABO-related antigen expression in urothelium from patients with chronic cystitis. (2644485)
1989
31
The management of chronic interstitial cystitis by substitution cystoplasty. (2913346)
1989
32
Chronic interstitial cystitis: a heterogeneous syndrome. (3795363)
1987
33
Chronic cystitis: excretion of epidermal growth factor (EGF)/urogastrone (URO). (3499698)
1987
34
The effects of chronic cystitis on vesicoureteral reflux in an animal model. (3510317)
1986
35
Chronic interstitial cystitis. (2862324)
1985
36
Chronic interstitial cystitis and subcutaneous heparin. (2865477)
1985
37
Chronic interstitial cystitis. (2862550)
1985
38
A light and electron microscopic study of urothelium from patients with chronic cystitis. (6479201)
1984
39
Haemorrhagic chronic radiation cystitis--following treatment of pelvic malignancies. (6529148)
1984
40
Histamine content and mast cell count of detrusor muscle in patients with interstitial cystitis and other types of chronic cystitis. (6626895)
1983
41
Chronic interstitial cystitis: increased levels of eosinophil cationic protein in serum and urine and an ameliorating effect of subcutaneous heparin. (6612233)
1983
42
Chronic cystitis: a non-diagnosis. (20469386)
1982
43
Clinicopathological conference: fifty-seven year old male with symptoms of chronic cystitis. (1054887)
1975
44
Treatment of chronic cystitis by instillation: experiments employing an artificial model. (4217003)
1974
45
Clinico-pathological conference: cellulitis, urolithiasis, chronic pyelonephritis, chronic cystitis and chronic prostatitis and cystic hyperplasia in a dog. (5104482)
1971
46
CARCINOMA OF THE BLADDER SIMULATING CHRONIC CYSTITIS. (14269353)
1965
47
HUNNER'S ULCER (CHRONIC INTERSTITIAL CYSTITIS). A MANIFESTATION OF COLLAGEN DISEASE. (14346453)
1965
48
The role of hyperemia in the treatment of chronic interstitial cystitis. (13783247)
1961
49
The clinical effect of pituitary adrenocorticotrophic hormone in three cases of severe chronic interstitial cystitis. (13062390)
1953
50
Remarks on a New Mode of Affording Permanent Relief to Intractable Chronic Cystitis, and to Confirmed Prostatic Retention of Urine. (20750395)
1882

Genetic Variations for Chronic Cystitis

About this section

Expression for genes affiliated with Chronic Cystitis

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Chronic Cystitis

Search GEO for disease gene expression data for Chronic Cystitis.

Pathways for genes affiliated with Chronic Cystitis

About this section
Sources:
53Reactome
See all sources

Pathways related to Chronic Cystitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.0KIT, NGF

Compounds for genes affiliated with Chronic Cystitis

About this section
Sources:
44Novoseek, 59Tocris Bioscience, 11DrugBank, 24HMDB, 49PharmGKB
See all sources

Compounds related to Chronic Cystitis according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
1pgj-2449.6PTGS1, NGF
2camptothecin44 59 1111.5NGF, PTGS1
3herbimycin a44 5910.4PTGS1, NGF
4choline44 11 2411.3NGF, PTGS1
5cytarabine44 49 1111.2KIT, NGF
6imatinib44 49 1111.0PTGS1, KIT
7prostacyclin449.0PTGS1, NGF
8valine449.0KIT, NGF
9actinomycin d448.8PTGS1, KIT, NGF
10cycloheximide448.7NGF, KIT, PTGS1
11vegf448.7PTGS1, KIT, NGF
12cysteine448.6PTGS1, KIT, NGF

GO Terms for genes affiliated with Chronic Cystitis

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Chronic Cystitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to radiationGO:0093149.1KIT, NGF
2regulation of cell proliferationGO:0421279.0KIT, PTGS1
3positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.0KIT, NGF
4phosphatidylinositol-mediated signalingGO:0480159.0KIT, NGF
5positive regulation of gene expressionGO:0106288.7KIT, NGF

Products for genes affiliated with Chronic Cystitis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Chronic Cystitis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet