MCID: CHR087
MIFTS: 29

Chronic Cystitis malady

Summaries for Chronic Cystitis

Sources:
33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Chronic Cystitis is related to urethritis and chronic interstitial cystitis. An important gene associated with Chronic Cystitis is PTGS1 (prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)), and among its related pathways is PIP3 activates AKT signaling. The compounds pgj-2 and camptothecin have been mentioned in the context of this disorder. Related mouse phenotype muscle.

Aliases & Classifications for Chronic Cystitis

Sources:
8Disease Ontology, 45Novoseek, 61UMLS, 27ICD9CM, 57SNOMED-CT
See all sources

Aliases & Descriptions:

chronic cystitis 8 45 61


External Ids:

Disease Ontology8 DOID:1680
ICD9CM27 595.2

Related Diseases for Chronic Cystitis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the cystitis family:

acute cystitis chronic cystitis

Diseases related to Chronic Cystitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 25)
idRelated DiseaseScoreTop Affiliating Genes
1urethritis10.2
2chronic interstitial cystitis10.2
3bladder carcinoma10.2
4prostatic cyst10.0
5cellulitis10.0
6non-invasive bladder urothelial carcinoma10.0
7bladder lymphoma10.0
8vesicoureteral reflux10.0
9acute cystitis10.0
10squamous cell carcinoma10.0
11malakoplakia10.0
12chronic pain10.0
13urticaria10.0PTGS1
14cystitis10.0NGF
15pheochromocytoma10.0NGF
16astrocytoma10.0NGF
17osteosarcoma10.0NGF
18desmoid tumor10.0KIT
19oligodendroglioma10.0PTGS1
20polycythemia vera10.0KIT
21teratoma10.0KIT
22asthma10.0NGF, PTGS1
23factor vii deficiency10.0NGF, KIT
24glioblastoma multiforme10.0KIT, NGF
25leukemia10.0NGF, KIT, PTGS1

Graphical network of the top 20 diseases related to Chronic Cystitis:



Diseases related to chronic cystitis

Clinical Features for Chronic Cystitis

Drugs & Therapeutics for Chronic Cystitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Chronic Cystitis

Drug clinical trials:

Search ClinicalTrials for Chronic Cystitis

Search NIH Clinical Center for Chronic Cystitis

Search CenterWatch for Chronic Cystitis

Genetic Tests for Chronic Cystitis

Anatomical Context for Chronic Cystitis

Animal Models for Chronic Cystitis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Chronic Cystitis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.9NGF

Publications for Chronic Cystitis

Sources:
51PubMed
See all sources

Articles related to Chronic Cystitis:

(show top 50)    (show all 91)
idTitleAuthorsYear
1
Interleukin-6 levels in female rats with protamine sulfate-induced chronic cystitis treated with hyaluronic acid. (23379983)
2013
2
Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model. (23806407)
2013
3
Editorial comment to interleukin-6 levels in female rats with protamine sulfate-induced chronic cystitis treated with hyaluronic acid. (23360376)
2013
4
What is your diagnosis? Lymphocytic and neutrophilic cystitis consistent with a chronic bacterial infection. (24134573)
2013
5
A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131. (23737602)
2013
6
Omega-3 supplementation and cardiovascular disease, acupuncture and chronic obstructive pulmonary disease (COPD), myofascial physical therapy and interstitial cystitis, and yoga and chronic pain. (23294822)
2013
7
Evaluation of the impact of the urinary symptoms on quality of life of patients with painful bladder syndrome/chronic pelvic pain and radiation cystitis: EURCIS study. (24360594)
2013
8
Intravesical hyaluronidase causes chronic cystitis in a rat model: A potential model of bladder pain syndrome/interstitial cystitis. (24286489)
2013
9
The subject, its biology, and the chronic recurrent cystitis. (22934220)
2012
10
Increased urine and serum nerve growth factor levels in interstitial cystitis suggest chronic inflammation is involved in the pathogenesis of disease. (23028581)
2012
11
Diagnosis of interstitial cystitis/bladder pain syndrome in women with chronic pelvic pain: a prospective observational study. (22398828)
2012
12
Chronic prostatitis, cystitis, pyelonephritis, and balanoposthitis in a cat. (21673330)
2011
13
The therapeutic challenge of "chronic cystitis": search well, work together, and gain results. (21474233)
2011
14
Interstitial cystitis/painful bladder syndrome and associated medical conditions with an emphasis on irritable bowel syndrome, fibromyalgia and chronic fatigue syndrome. (20719340)
2010
15
A new approach to understanding and managing chronic prostatitis and interstitial cystitis. (20428298)
2010
16
Decreased viral load and symptoms of polyomavirus-associated chronic interstitial cystitis after intravesical cidofovir treatment. (19292661)
2009
17
Words of wisdom. Re: Clinical phenotyping in chronic prostatitis/chronic pelvic pain syndrome and interstitial cystitis: a management strategy for urologic chronic pelvic pain syndromes. (20965030)
2009
18
Mental health diagnoses in patients with interstitial cystitis/painful bladder syndrome and chronic prostatitis/chronic pelvic pain syndrome: a case/control study. (18707716)
2008
19
Chronic prostatitis/chronic pelvic pain syndrome and male interstitial cystitis: enigmas and opportunities. (17462482)
2007
20
Intravesical botulinum toxin type A in chronic interstitial cystitis: results of a pilot study. (18080606)
2007
21
Chronic cystitis with ossification of the bladder wall in a 6-month-old German shepherd dog. (17966335)
2007
22
Antiproliferative factor, heparin-binding epidermal growth factor-like growth factor, and epidermal growth factor in men with interstitial cystitis versus chronic pelvic pain syndrome. (14751340)
2004
23
Recurrent eosinophilic cystitis in a child with chronic granulomatous disease. (15125617)
2004
24
A case of cannabinoid rotation in a young woman with chronic cystitis. (12565180)
2003
25
Biosynthetic reactions and ultrastructure of urothelial cells in chronic cystitis and cystopathies. (12512008)
2002
26
Lipofuscinosis of the urinary bladder: a complication of chronic interstitial cystitis. (12418480)
2002
27
Spontaneous bladder rupture due to chronic cystitis 20 years after cystolithotomy. (12444296)
2002
28
Alterations in neuropeptide expression in lumbosacral bladder pathways following chronic cystitis. (11312054)
2001
29
Up-regulation of pituitary adenylate cyclase-activating polypeptide in urinary bladder pathways after chronic cystitis. (10754506)
2000
30
Chronic interstitial cystitis and systemic lupus erythematosus in an 8-year-old girl. (9543374)
1998
31
Chronic interstitial cystitis occurring during the shift between rheumatoid arthritis and lupus. (8187433)
1994
32
Chronic interstitial cystitis. Successful treatment with intravesical idocaine. (1462157)
1992
33
The management of chronic interstitial cystitis by substitution cystoplasty. (2913346)
1989
34
The effects of chronic cystitis on vesicoureteral reflux in an animal model. (3510317)
1986
35
Conservative management of chronic interstitial cystitis: transcutaneous electrical nerve stimulation and transurethral resection. (3872946)
1985
36
Chronic interstitial cystitis. (2862550)
1985
37
Chronic cystitis and urethritis associated with ureaplasmal and mycoplasmal infection in primary hypogammaglobulinaemia. (7104592)
1982
38
Chronic interstitial cystitis as an initial major manifestation of systemic lupus erythematosus. (6975827)
1981
39
The surgical treatment of chronic interstitial cystitis. (875802)
1977
40
Cefuroxime in chronic and acute cystitis. (20919398)
1977
41
Chronic renal failure due to eosinophilic cystitis. (5056912)
1972
42
Allopurinol in treatment of chronic "cystitis" in a Dalmatian dog. (4481108)
1972
43
Chronic interstitial cystitis. (5159574)
1971
44
Psychometric testing with the human figure drawing in chronic cystitis. (5532923)
1970
45
Operative treatment of chronic cystitis by urethrotomy: 10 years of experience. (5461833)
1970
46
Functional abnormalities of the bladder in children: characteristics of chronic cystitis and chronic urethritis. (5532922)
1970
47
Surgical treatment of chronic cystitis in a bitch. (5812943)
1969
48
The management of chronic interstitial cystitis by differential sacral neurotomy. (5782386)
1969
49
CARCINOMA OF THE BLADDER SIMULATING CHRONIC CYSTITIS. (14269353)
1965
50
Chronic interstitial cystitis. (13832744)
1960

Genetic Variations for Chronic Cystitis

Expression for genes affiliated with Chronic Cystitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Chronic Cystitis

Search GEO for disease gene expression data for Chronic Cystitis.

Pathways for genes affiliated with Chronic Cystitis

Sources:
54Reactome
See all sources

Pathways related to Chronic Cystitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.0KIT, NGF

Compounds for genes affiliated with Chronic Cystitis

Sources:
45Novoseek, 60Tocris Bioscience, 11DrugBank, 24HMDB, 50PharmGKB
See all sources

Compounds related to Chronic Cystitis according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
1pgj-2459.6PTGS1, NGF
2camptothecin45 60 1111.5NGF, PTGS1
3herbimycin a45 6010.4PTGS1, NGF
4choline45 11 2411.3NGF, PTGS1
5cytarabine45 50 1111.2KIT, NGF
6imatinib45 50 1111.0PTGS1, KIT
7prostacyclin459.0PTGS1, NGF
8valine459.0KIT, NGF
9actinomycin d458.8PTGS1, KIT, NGF
10cycloheximide458.7NGF, KIT, PTGS1
11vegf458.7PTGS1, KIT, NGF
12cysteine458.6PTGS1, KIT, NGF

GO Terms for genes affiliated with Chronic Cystitis

Sources:
16Gene Ontology
See all sources

Biological processes related to Chronic Cystitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to radiationGO:0093149.1KIT, NGF
2regulation of cell proliferationGO:0421279.0KIT, PTGS1
3positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.0KIT, NGF
4phosphatidylinositol-mediated signalingGO:0480159.0KIT, NGF
5positive regulation of gene expressionGO:0106288.7KIT, NGF

Products for genes affiliated with Chronic Cystitis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Chronic Cystitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet