MCID: CHR087
MIFTS: 33

Chronic Cystitis malady

Summaries for Chronic Cystitis

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Chronic Cystitis is related to cystitis and urethritis. An important gene associated with Chronic Cystitis is PTGS1 (prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)), and among its related pathways is PIP3 activates AKT signaling. The compounds pgj-2 and camptothecin have been mentioned in the context of this disorder. Affiliated tissues include prostate, pituitary and testes, and related mouse phenotype muscle.

Aliases & Classifications for Chronic Cystitis

About this section
Sources:
8Disease Ontology, 44Novoseek, 60UMLS, 27ICD9CM, 56SNOMED-CT
See all sources

Aliases & Descriptions:

chronic cystitis 8 44 60


External Ids:

Disease Ontology8 DOID:1680
ICD9CM27 595.2

Related Diseases for Chronic Cystitis

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Cystitis family:

Acute Cystitis chronic cystitis

Diseases related to Chronic Cystitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 24)
idRelated DiseaseScoreTop Affiliating Genes
1cystitis31.1NGF
2urethritis10.1
3chronic interstitial cystitis10.1
4bladder carcinoma10.1
5prostatitis10.1
6cellulitis10.0
7bladder lymphoma10.0
8vesicoureteral reflux10.0
9acute cystitis10.0
10chronic pyelonephritis10.0
11pyelonephritis10.0
12squamous cell carcinoma10.0
13urticaria10.0PTGS1
14pheochromocytoma10.0NGF
15astrocytoma10.0NGF
16osteosarcoma10.0NGF
17desmoid tumor10.0KIT
18oligodendroglioma10.0PTGS1
19polycythemia vera10.0KIT
20teratoma10.0KIT
21asthma10.0NGF, PTGS1
22factor vii deficiency10.0NGF, KIT
23glioblastoma multiforme10.0KIT, NGF
24leukemia10.0NGF, KIT, PTGS1

Graphical network of the top 20 diseases related to Chronic Cystitis:



Diseases related to chronic cystitis

Clinical Features for Chronic Cystitis

About this section

Drugs & Therapeutics for Chronic Cystitis

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Chronic Cystitis

Drug clinical trials:

Search ClinicalTrials for Chronic Cystitis

Search NIH Clinical Center for Chronic Cystitis

Search CenterWatch for Chronic Cystitis

Genetic Tests for Chronic Cystitis

About this section

Anatomical Context for Chronic Cystitis

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Chronic Cystitis:

32
Prostate, Pituitary, Testes, Spinal cord

Animal Models for Chronic Cystitis or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Chronic Cystitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.9NGF

Publications for Chronic Cystitis

About this section
Sources:
50PubMed
See all sources

Articles related to Chronic Cystitis:

(show top 50)    (show all 89)
idTitleAuthorsYear
1
Intravesical glycosaminoglycans in the management of chronic cystitis. (24091478)
2013
2
Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model. (23806407)
2013
3
Editorial comment to interleukin-6 levels in female rats with protamine sulfate-induced chronic cystitis treated with hyaluronic acid. (23360376)
2013
4
MicroRNA-mediated GABA AI+-1 receptor subunit down-regulation in adult spinal cord following neonatal cystitis-induced chronic visceral pain in rats. (23273104)
2013
5
Omega-3 supplementation and cardiovascular disease, acupuncture and chronic obstructive pulmonary disease (COPD), myofascial physical therapy and interstitial cystitis, and yoga and chronic pain. (23294822)
2013
6
Intravesical hyaluronidase causes chronic cystitis in a rat model: A potential model of bladder pain syndrome/interstitial cystitis. (24286489)
2013
7
GAG layer replenishment therapy for chronic forms of cystitis with intravesical glycosaminoglycans--a review. (22782909)
2013
8
The subject, its biology, and the chronic recurrent cystitis. (22934220)
2012
9
Reinforcements arrive for the war against chronic cystitis and bladder cancer. (22882427)
2012
10
Pain: Novel lidocaine delivery device for chronic interstitial cystitis. (22890300)
2012
11
Diagnosis of interstitial cystitis/bladder pain syndrome in women with chronic pelvic pain: a prospective observational study. (22398828)
2012
12
Chronic prostatitis, cystitis, pyelonephritis, and balanoposthitis in a cat. (21673330)
2011
13
The role of a leaky epithelium and potassium in the generation of bladder symptoms in interstitial cystitis/overactive bladder, urethral syndrome, prostatitis and gynaecological chronic pelvic pain. (21176078)
2011
14
Sequestration of brain derived nerve factor by intravenous delivery of TrkB-Ig2 reduces bladder overactivity and noxious input in animals with chronic cystitis. (20079809)
2010
15
Decreased viral load and symptoms of polyomavirus-associated chronic interstitial cystitis after intravesical cidofovir treatment. (19292661)
2009
16
Clinical phenotyping in chronic prostatitis/chronic pelvic pain syndrome and interstitial cystitis: a management strategy for urologic chronic pelvic pain syndromes. (18645581)
2009
17
Words of wisdom. Re: Clinical phenotyping in chronic prostatitis/chronic pelvic pain syndrome and interstitial cystitis: a management strategy for urologic chronic pelvic pain syndromes. (20965030)
2009
18
Comparison of economic impact of chronic prostatitis/chronic pelvic pain syndrome and interstitial cystitis/painful bladder syndrome. (19193408)
2009
19
Mental health diagnoses in patients with interstitial cystitis/painful bladder syndrome and chronic prostatitis/chronic pelvic pain syndrome: a case/control study. (18707716)
2008
20
Chronic prostatitis/chronic pelvic pain syndrome and male interstitial cystitis: enigmas and opportunities. (17462482)
2007
21
Intravesical botulinum toxin type A in chronic interstitial cystitis: results of a pilot study. (18080606)
2007
22
Chronic cystitis with ossification of the bladder wall in a 6-month-old German shepherd dog. (17966335)
2007
23
The effect of chronic inflammatory condition of the bladder and estrogen replacement therapy on bladder functions and histology in surgically menopause and chronic cystitis induced rats. (16267856)
2006
24
Preliminary results of suburothelial injection of botulinum a toxin in the treatment of chronic interstitial cystitis. (16123573)
2005
25
Recurrent eosinophilic cystitis in a child with chronic granulomatous disease. (15125617)
2004
26
Lipofuscinosis of the urinary bladder: a complication of chronic interstitial cystitis. (12418480)
2002
27
Chronic cystitis caused by Corynebacterium urealyticum detected by polymerase chain reaction. (11205634)
2000
28
Concurrent malakoplakia and primary squamous cell carcinoma arising in long-standing chronic cystitis. (7827859)
1994
29
Management of severe chronic radiation cystitis. (1416787)
1992
30
Association of chronic interstitial cystitis, protein-losing enteropathy and paralytic ileus with seronegative systemic lupus erythematosus: case report and review of the literature. (1606774)
1992
31
Vesical manifestations of chronic granulomatous disease in children. Its relation to eosinophilic cystitis. (2024396)
1991
32
Chronic interstitial cystitis: a heterogeneous syndrome. (3795363)
1987
33
Chronic cystitis: excretion of epidermal growth factor (EGF)/urogastrone (URO). (3499698)
1987
34
The effects of chronic cystitis on vesicoureteral reflux in an animal model. (3510317)
1986
35
Chronic interstitial cystitis and subcutaneous heparin. (2865477)
1985
36
A light and electron microscopic study of urothelium from patients with chronic cystitis. (6479201)
1984
37
Chronic interstitial cystitis: increased levels of eosinophil cationic protein in serum and urine and an ameliorating effect of subcutaneous heparin. (6612233)
1983
38
Chronic interstitial cystitis as an initial major manifestation of systemic lupus erythematosus. (6975827)
1981
39
Cefuroxime in chronic and acute cystitis. (20919398)
1977
40
Clinicopathological conference: fifty-seven year old male with symptoms of chronic cystitis. (1054887)
1975
41
Treatment of chronic cystitis by instillation: experiments employing an artificial model. (4217003)
1974
42
Chronic renal failure due to eosinophilic cystitis. (5056912)
1972
43
Clinico-pathological conference: cellulitis, urolithiasis, chronic pyelonephritis, chronic cystitis and chronic prostatitis and cystic hyperplasia in a dog. (5104482)
1971
44
Psychometric testing with the human figure drawing in chronic cystitis. (5532923)
1970
45
Functional abnormalities of the bladder in children: characteristics of chronic cystitis and chronic urethritis. (5532922)
1970
46
The management of chronic interstitial cystitis by differential sacral neurotomy. (5782386)
1969
47
CARCINOMA OF THE BLADDER SIMULATING CHRONIC CYSTITIS. (14269353)
1965
48
HUNNER'S ULCER (CHRONIC INTERSTITIAL CYSTITIS). A MANIFESTATION OF COLLAGEN DISEASE. (14346453)
1965
49
Chronic interstitial cystitis. (13832744)
1960
50
The clinical effect of pituitary adrenocorticotrophic hormone in three cases of severe chronic interstitial cystitis. (13062390)
1953

Genetic Variations for Chronic Cystitis

About this section

Expression for genes affiliated with Chronic Cystitis

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Chronic Cystitis

Search GEO for disease gene expression data for Chronic Cystitis.

Pathways for genes affiliated with Chronic Cystitis

About this section
Sources:
53Reactome
See all sources

Pathways related to Chronic Cystitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.0KIT, NGF

Compounds for genes affiliated with Chronic Cystitis

About this section
Sources:
44Novoseek, 59Tocris Bioscience, 11DrugBank, 24HMDB, 49PharmGKB
See all sources

Compounds related to Chronic Cystitis according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
1pgj-2449.6NGF, PTGS1
2camptothecin44 59 1111.5PTGS1, NGF
3herbimycin a44 5910.4PTGS1, NGF
4choline44 11 2411.3NGF, PTGS1
5cytarabine44 49 1111.2NGF, KIT
6imatinib44 49 1111.0PTGS1, KIT
7prostacyclin449.0PTGS1, NGF
8valine449.0NGF, KIT
9actinomycin d448.8NGF, KIT, PTGS1
10cycloheximide448.7PTGS1, KIT, NGF
11vegf448.7PTGS1, KIT, NGF
12cysteine448.6NGF, KIT, PTGS1

GO Terms for genes affiliated with Chronic Cystitis

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Chronic Cystitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to radiationGO:0093149.1KIT, NGF
2regulation of cell proliferationGO:0421279.0PTGS1, KIT
3positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.0KIT, NGF
4phosphatidylinositol-mediated signalingGO:0480159.0KIT, NGF
5positive regulation of gene expressionGO:0106288.7NGF, KIT

Products for genes affiliated with Chronic Cystitis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Chronic Cystitis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet