MCID: CHR040
MIFTS: 22

Chronic Frontal Sinusitis

Categories: Respiratory diseases

Aliases & Classifications for Chronic Frontal Sinusitis

MalaCards integrated aliases for Chronic Frontal Sinusitis:

Name: Chronic Frontal Sinusitis 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:10790
ICD10 33 J32.1
ICD9CM 35 473.1
NCIt 47 C34473
UMLS 69 C0008683

Summaries for Chronic Frontal Sinusitis

Disease Ontology : 12 A frontal sinusitis which lasts for 12 weeks or more. This causes steady headache, localized tenderness and intermittent, purulent nasal and postnasal drainage.

MalaCards based summary : Chronic Frontal Sinusitis is related to frontal sinusitis and sinusitis. An important gene associated with Chronic Frontal Sinusitis is RHNO1 (RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1). The drugs Hemostatics and Anti-Allergic Agents have been mentioned in the context of this disorder. Affiliated tissues include bone.

Related Diseases for Chronic Frontal Sinusitis

Diseases in the Sinusitis family:

Chronic Frontal Sinusitis Frontal Sinusitis
Acute Frontal Sinusitis

Diseases related to Chronic Frontal Sinusitis via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 frontal sinusitis 11.0
2 sinusitis 10.5
3 mucositis 9.7
4 chronic sphenoidal sinusitis 8.4 CAGE1 MAEA RHNO1 TUBE1
5 chronic maxillary sinusitis 8.0 CAGE1 MAEA RHNO1 TUBE1

Comorbidity relations with Chronic Frontal Sinusitis via Phenotypic Disease Network (PDN):


Bronchitis Chronic Ethmoiditis
Chronic Maxillary Sinusitis Hypertension, Essential

Graphical network of the top 20 diseases related to Chronic Frontal Sinusitis:



Diseases related to Chronic Frontal Sinusitis

Symptoms & Phenotypes for Chronic Frontal Sinusitis

Drugs & Therapeutics for Chronic Frontal Sinusitis

Drugs for Chronic Frontal Sinusitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Hemostatics Phase 4
2 Anti-Allergic Agents Phase 3
3 Anti-Inflammatory Agents Phase 3,Phase 2
4 Dermatologic Agents Phase 3
5 mometasone furoate Phase 3 83919-23-7
6
Budesonide Approved Phase 2 51333-22-3 63006 5281004
7 Anti-Asthmatic Agents Phase 2
8 Autonomic Agents Phase 2
9 Bronchodilator Agents Phase 2
10 glucocorticoids Phase 2
11 Hormone Antagonists Phase 2
12 Hormones Phase 2
13 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
14 Peripheral Nervous System Agents Phase 2
15 Pharmaceutical Solutions Phase 2
16 Respiratory System Agents Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Improvement of Outcomes in Draf III/Endoscopic Modified Lothrop Procedure Recruiting NCT02981017 Phase 4
2 Canadian Health Economics, Outcome, and Effectiveness Comparison of Treatment in Patients With Chronic Rhinosinusitis Terminated NCT01455948 Phase 4
3 Safety and Efficacy of the Propel Mini and Propel Nova Steroid-Eluting Sinus Implant in Frontal Sinus Completed NCT02266810 Phase 3
4 Effectiveness of Budesonide Nasal Instillation in a Vertex-to-floor Position Active, not recruiting NCT02862509 Phase 2 Budesonide nasal instillation;Normal saline nasal instillation
5 Treatment of Chronic Frontal Sinusitis by a Simple Technique Using Dilation Balloons Unknown status NCT02509663
6 SinuSys Patency of Frontal Recess and Sphenoid Sinus Ostia Study Completed NCT02463279
7 Study to Compare Resection Versus Preservation of the Middle Turbinate in Surgery for Nasal Polyps Recruiting NCT02855931
8 A Clinical Evaluation of Propel Mini Sinus Implant Placement in the Frontal Sinus Ostia Following In-office Dilation Active, not recruiting NCT02880514

Search NIH Clinical Center for Chronic Frontal Sinusitis

Genetic Tests for Chronic Frontal Sinusitis

Anatomical Context for Chronic Frontal Sinusitis

MalaCards organs/tissues related to Chronic Frontal Sinusitis:

39
Bone

Publications for Chronic Frontal Sinusitis

Articles related to Chronic Frontal Sinusitis:

(show all 42)
id Title Authors Year
1
Outcomes of chronic frontal sinusitis treated with ethmoidectomy: a prospective study. ( 26879467 )
2016
2
Endoscopic Management of Chronic Frontal Sinusitis: Prospective Quality of Life Analysis. ( 25736024 )
2015
3
Treatment of chronic frontal sinusitis with difficult anatomy: A hybrid balloon technique in four cases. ( 25565046 )
2014
4
The association of frontal recess anatomy and mucosal disease on the presence of chronic frontal sinusitis: a computed tomographic analysis. ( 25271525 )
2014
5
Efficacy of the modified endoscopic frontal sinus surgery for recurrent chronic frontal sinusitis. ( 25032109 )
2014
6
Cranialization of the frontal sinus--the final remedy for refractory chronic frontal sinusitis. ( 22175720 )
2012
7
Balloon dilation of the frontal recess in patients with chronic frontal sinusitis and advanced sinus disease: an initial report. ( 19708496 )
2009
8
Balloon dilation of the frontal recess in patients with chronic frontal sinusitis and advanced sinus disease: an initial report. ( 19326760 )
2009
9
Initial surgical treatment for chronic frontal sinusitis: a pilot study. ( 17491529 )
2007
10
Endoscopic frontal sinus obliteration: a new technique for the treatment of chronic frontal sinusitis. ( 16213928 )
2005
11
Upper eyelid fistula caused by chronic frontal sinusitis. ( 15699670 )
2005
12
The endoscopic modified Lothrop procedure for salvage of chronic frontal sinusitis after osteoplastic flap failure. ( 14663435 )
2003
13
Acute and chronic frontal sinusitis. ( 12682560 )
2003
14
The modified endoscopic Lothrop procedure in the treatment of complicated chronic frontal sinusitis. ( 12755759 )
2003
15
Endoscopic modified Lothrop procedure for the treatment of chronic frontal sinusitis: a systematic review. ( 14574300 )
2003
16
Bacteriology of acute and chronic frontal sinusitis. ( 12003592 )
2002
17
Microbiology of chronic frontal sinusitis. ( 11568564 )
2001
18
Surgical treatments for symptomatic chronic frontal sinusitis. ( 10628724 )
2000
19
The endoscopic management of chronic frontal sinusitis associated with frontal sinus posterior table erosion. ( 10793915 )
2000
20
Osteoplastic flap with obliteration: is this an ideal procedure for chronic frontal sinusitis? ( 10628723 )
2000
21
Current concepts in the surgical management of chronic frontal sinusitis. ( 9162122 )
1997
22
Chronic frontal sinusitis showing a ring-like accumulation demonstrated by Tc-99m HMDP bone imaging. ( 9363399 )
1997
23
Role of the agger nasi cell in chronic frontal sinusitis. ( 8800055 )
1996
24
Chronic frontal sinusitis in dairy cattle: 12 cases (1978-1989). ( 1500335 )
1992
25
Chronic frontal sinusitis and osteolysis in desert bighorn sheep. ( 738941 )
1978
26
Autogenous fat implantation as a treatment for chronic frontal sinusitis in a cat. ( 1184421 )
1975
27
An unusual case of chronic frontal sinusitis: treatment by osteoplastic surgery. ( 5014393 )
1972
28
Chronic frontal sinusitis treated by autogenous osteoplasty. ( 4939713 )
1971
29
Chronic frontal sinusitis. Obliterative surgery and obliterative disease. ( 14401846 )
1960
30
Chronic frontal sinusitis: end results of surgical treatment. ( 13486578 )
1957
31
Operation for chronic frontal sinusitis. ( 13217564 )
1955
32
Present state of the surgical treatment of chronic frontal sinusitis. ( 14375470 )
1955
33
Management of chronic frontal sinusitis. ( 13113755 )
1954
34
Surgical treatment of chronic frontal sinusitis. ( 14944154 )
1952
35
Surgical treatment of chronic frontal sinusitis. ( 13005594 )
1952
36
OPERATIVE treatment of chronic frontal sinusitis. ( 14911837 )
1951
37
Surgical treatment of chronic frontal sinusitis. ( 20342962 )
1947
38
Role of penicillin in the management of acute and chronic frontal sinusitis. ( 20265705 )
1947
39
The surgical treatment of chronic frontal sinusitis. ( 20244689 )
1947
40
Surgical treatment of chronic frontal sinusitis. ( 21015219 )
1946
41
Causes of Failure in the Surgical Treatment of Chronic Frontal Sinusitis. ( 19993062 )
1945
42
The Treatment of Chronic Frontal Sinusitis. ( 19988067 )
1931

Variations for Chronic Frontal Sinusitis

Expression for Chronic Frontal Sinusitis

Search GEO for disease gene expression data for Chronic Frontal Sinusitis.

Pathways for Chronic Frontal Sinusitis

GO Terms for Chronic Frontal Sinusitis

Biological processes related to Chronic Frontal Sinusitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell cycle GO:0007049 8.62 MAEA RHNO1

Sources for Chronic Frontal Sinusitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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