Chronic Inflammatory Demyelinating Polyneuropathy malady
Categories: Rare diseases, Neuronal diseases
Aliases & Descriptions for Chronic Inflammatory Demyelinating Polyneuropathy:
Orphanet epidemiological data:51
chronic inflammatory demyelinating polyneuropathy:
Inheritance: Not applicable; Age of onset: Childhood; Age of death: normal life expectancy
Global: Rare diseases
Anatomical: Neuronal diseases
Rare neurological diseases
NIH Rare Diseases:45 Chronic inflammatory demyelinating polyneuropathy (cidp) is a neurological disorder that causes progressive weakness and impaired sensory function in the legs and arms. symptoms often include tingling or numbness (first in the toes and fingers); weakness of the arms and legs; loss of deep tendon reflexes; fatigue; and abnormal sensations. cidp is thought to be caused by an abnormal immune response in which the immune system mistakenly attacks and damages the myelin sheath (the covering that protects nerve fibers) of the peripheral nerves. cidp is closely related to guillain-barre syndrome (gbs) and is considered the "chronic counterpart" of gbs. treatment may include corticosteroids, immunosuppressant drugs, plasma exchange, physiotherapy, and/or intravenous immunoglobulin (ivig) therapy. last updated: 11/23/2015
MalaCards based summary: Chronic Inflammatory Demyelinating Polyneuropathy, also known as chronic inflammatory demyelinating polyradiculoneuropathy, is related to chronic inflammatory demyelinating polyradiculoneuropathy and polyneuropathy. An important gene associated with Chronic Inflammatory Demyelinating Polyneuropathy is AIF1 (Allograft Inflammatory Factor 1). The drug immunoglobulins, intravenous has been mentioned in the context of this disorder. Affiliated tissues include kidney, brain and thyroid, and related mouse phenotypes are hematopoietic system and immune system.
NINDS:46 Chronic inflammatory demyelinating polyneuropathy (CIDP) is a neurological disorder characterized by progressive weakness and impaired sensory function in the legs and arms. The disorder, which is sometimes called chronic relapsing polyneuropathy, is caused by damage to the myelin sheath (the fatty covering that wraps around and protects nerve fibers) of the peripheral nerves. Although it can occur at any age and in both genders, CIDP is more common in young adults, and in men more so than women. It often presents with symptoms that include tingling or numbness (beginning in the toes and fingers), weakness of the arms and legs, loss of deep tendon reflexes (areflexia), fatigue, and abnormal sensations. CIDP is closely related to Guillain-Barre syndrome and it is considered the chronic counterpart of that acute disease.
Wikipedia:68 Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired immune-mediated inflammatory... more...
Drugs for Chronic Inflammatory Demyelinating Polyneuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):(show all 47)
Interventional clinical trials:(show all 37)
Search NIH Clinical Center for Chronic Inflammatory Demyelinating Polyneuropathy
Inferred drug relations via UMLS65/NDF-RT43:
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Chronic Inflammatory Demyelinating Polyneuropathy cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Chronic Inflammatory Demyelinating Polyneuropathy:
Embryonic/Adult Cultured Cells Related to Chronic Inflammatory Demyelinating Polyneuropathy:
MalaCards organs/tissues related to Chronic Inflammatory Demyelinating Polyneuropathy:33
Kidney, Brain, Thyroid, Lung, T cells, Endothelial, Liver
Articles related to Chronic Inflammatory Demyelinating Polyneuropathy:(show top 50) (show all 498)
Search GEO for disease gene expression data for Chronic Inflammatory Demyelinating Polyneuropathy.
28ICD10 via Orphanet
37MESH via Orphanet
50OMIM via Orphanet
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
66UMLS via Orphanet