MCID: CHR070
MIFTS: 54

Chronic Inflammatory Demyelinating Polyradiculoneuropathy malady

Neuronal diseases category

Summaries for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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34MalaCards
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MalaCards: Chronic Inflammatory Demyelinating Polyradiculoneuropathy, also known as polyradiculoneuropathy, chronic inflammatory demyelinating, is related to polyradiculoneuropathy and neuropathy. An important gene associated with Chronic Inflammatory Demyelinating Polyradiculoneuropathy is MPZ (myelin protein zero), and among its related pathways are Cytokine Network and Inflammatory Response Pathway. The drug immunoglobulins, intravenous and the compounds indoleamine and imiquimod have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, t cells and brain, and related mouse phenotypes are tumorigenesis and liver/biliary system.

Aliases & Classifications for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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9Disease Ontology, 11DISEASES, 46Novoseek, 63UMLS, 41NCIt, 36MeSH, 59SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

chronic inflammatory demyelinating polyradiculoneuropathy 9 11
polyradiculoneuropathy, chronic inflammatory demyelinating 63
polyradiculoneuropathy chronic inflammatory demyelinating 46


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Disease Ontology9 DOID:5213
NCIt41 C84636
SNOMED-CT59 128209004
MeSH36 D020277

Related Diseases for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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18GeneCards, 19GeneDecks
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Diseases related to Chronic Inflammatory Demyelinating Polyradiculoneuropathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 125)
idRelated DiseaseScoreTop Affiliating Genes
1polyradiculoneuropathy32.5PMP22
2neuropathy31.1MBP, ALB, MPZ, PMP22
3systemic lupus erythematosus30.9HLA-DRB1, STAT1, IFNB1, IFNG, CD40LG
4neuritis30.8PMP22, MPZ, MBP
5diabetes mellitus30.8HLA-DRB1, PMP22, ALB, CD40LG
6polyneuropathy30.7CD40LG, MBP, MPZ, PMP22
7hereditary neuropathy with liability to pressure palsies30.7PMP22
8hereditary neuropathies30.6PMP22, MPZ
9optic neuritis30.6MBP, IFNB1, MPZ
10type 1 diabetes mellitus30.5IFNG, HLA-DRB1
11guillain-barre syndrome30.5PMP22, MPZ, MBP, CD40LG
12influenza30.5STAT1, CCL19, IFNB1, IFNG
13graft versus host disease30.5IFNG, CXCL12, HLA-DRB1
14multiple sclerosis30.5HLA-DRB1, SH2D2A, MPZ, MBP, TBX21, ALB
15inflammatory bowel disease30.4IFNG, STAT1, STAT3
16hepatocellular carcinoma30.2HLA-DRB1, CXCL12, STAT3, CCL19, CCL21, IFNB1
17lupus erythematosus10.6
18multifocal motor neuropathy10.6
19cervicitis10.6
20chronic inflammatory demyelinating polyneuropathy10.6
21membranous glomerulonephritis10.5
22glomerulonephritis10.5
23myasthenia gravis10.5
24ophthalmoplegia10.5
25autonomic dysfunction10.5
26crohn's disease10.3
27neurofibromatosis10.3
28lateral sclerosis10.3
29evans' syndrome10.3
30cauda equina syndrome10.3
31radiculopathy10.3
32aseptic meningitis10.3
33amyotrophic lateral sclerosis10.3
34arthropathy10.3
35demyelinating polyneuropathy10.3
36hypertension10.3
37intracranial hypertension10.3
38meningitis10.3
39psoriasis10.3
40respiratory failure10.3
41castleman's disease10.3
42chronic graft versus host disease10.3
43encephalomyopathy10.3
44hereditary neuropathy with liability to pressure palsy10.3
45ataxia10.3
46myokymia10.3
47blindness10.3
48lewis-sumner syndrome10.3
49hematopoietic stem cell transplantation10.3
50acute disseminated encephalomyelitis10.1MBP

Graphical network of the top 20 diseases related to Chronic Inflammatory Demyelinating Polyradiculoneuropathy:



Diseases related to chronic inflammatory demyelinating polyradiculoneuropathy

Symptoms for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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Drugs & Therapeutics for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Drug clinical trials:

Search ClinicalTrials for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Search NIH Clinical Center for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Search CenterWatch for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Inferred drug relations via UMLS63/NDF-RT42:

Genetic Tests for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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Anatomical Context for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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34MalaCards
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MalaCards organs/tissues related to Chronic Inflammatory Demyelinating Polyradiculoneuropathy:

34
Spinal cord, T cells, Brain, Tongue, Kidney, Liver, Skin

Animal Models for Chronic Inflammatory Demyelinating Polyradiculoneuropathy or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Chronic Inflammatory Demyelinating Polyradiculoneuropathy:

38 (show all 14)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.7STAT3, STAT1, IFNB1, IFNG, ALB, TBX21
2MP:00053708.7CXCL12, STAT3, STAT1, IFNG, ALB
3MP:00053918.7MBP, IFNG, STAT1, STAT3, PMP22
4MP:00053818.6STAT3, STAT1, IFNG, ALB, TBX21
5MP:00053698.5PMP22, CXCL12, STAT3, STAT1, IFNG, ALB
6MP:00053858.3CXCL12, STAT3, STAT1, IFNG, TBX21, CD40LG
7MP:00053898.2PMP22, MPZ, CXCL12, STAT3, IFNG, MBP
8MP:00028738.0CXCL12, STAT3, STAT1, IFNB1, IFNG, ALB
9MP:00053767.6MPZ, STAT3, STAT1, IFNB1, IFNG, ALB
10MP:00036317.5STAT3, CXCL12, MPZ, PMP22, STAT1, IFNB1
11MP:00107687.5PMP22, MPZ, CXCL12, STAT3, STAT1, IFNG
12MP:00053847.4STAT3, CXCL12, MPZ, PMP22, STAT1, IFNG
13MP:00053976.7CD40LG, SH2D2A, MPZ, CXCL12, STAT3, STAT1
14MP:00053876.7STAT3, CXCL12, MPZ, SH2D2A, STAT1, CCL19

Publications for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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53PubMed
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Articles related to Chronic Inflammatory Demyelinating Polyradiculoneuropathy:

(show top 50)    (show all 255)
idTitleAuthorsYear
1
SjAPgren's syndrome associated chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) treated with autologous and subsequently allogeneic haematopoietic SCT (HSCT). (23503533)
2013
2
Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with Crohn's disease. (23291687)
2013
3
Chronic inflammatory demyelinating polyradiculoneuropathy associated intracranial hypertension. (22941356)
2013
4
Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with systemic lupus erythematosus and good outcome with rituximab treatment. (21922339)
2012
5
CD8+ T-cell immunity in chronic inflammatory demyelinating polyradiculoneuropathy. (22238416)
2012
6
Chronic inflammatory demyelinating polyradiculoneuropathy: from bench to bedside. (23117943)
2012
7
Brachial and lumbar plexuses in chronic inflammatory demyelinating polyradiculoneuropathy: MRI assessment including apparent diffusion coefficient. (20405114)
2011
8
Diffusion tensor imaging of peripheral nerve in patients with chronic inflammatory demyelinating polyradiculoneuropathy: a feasibility study. (21318578)
2011
9
Pulsed high-dose dexamethasone versus standard prednisolone treatment for chronic inflammatory demyelinating polyradiculoneuropathy (PREDICT study): a double-blind, randomised, controlled trial. (20133204)
2010
10
Understanding the consequences of chronic inflammatory demyelinating polyradiculoneuropathy from impairments to activity and participation restrictions and reduced quality of life: the ICE study. (21040143)
2010
11
Alemtuzumab: the future of chronic inflammatory demyelinating polyradiculoneuropathy treatment? (20441416)
2010
12
Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy. (19160200)
2009
13
pSTAT1, pSTAT3, and T-bet as markers of disease activity in chronic inflammatory demyelinating polyradiculoneuropathy. (19691533)
2009
14
Chronic inflammatory demyelinating polyradiculoneuropathy: a role for haematopoietic stem cell transplantation? (18958756)
2008
15
What's new in chronic inflammatory demyelinating polyradiculoneuropathy in 2007-2008? (19192063)
2008
16
Recommendations on diagnostic strategies for chronic inflammatory demyelinating polyradiculoneuropathy. (18716018)
2008
17
Recommendations on diagnostic strategies for chronic inflammatory demyelinating polyradiculoneuropathy. (18202204)
2008
18
Muscle performance relates to physical function and quality of life in long-term chronic inflammatory demyelinating polyradiculoneuropathy. (18844787)
2008
19
Ophthalmoplegia, proptosis, and lid retraction caused by cranial nerve hypertrophy in chronic inflammatory demyelinating polyradiculoneuropathy. (17548992)
2007
20
Plasmapheresis for chronic inflammatory demyelinating polyradiculoneuropathy. (17547849)
2007
21
Rituximab therapy in chronic inflammatory demyelinating polyradiculoneuropathy with anti-SGPG IgM antibody. (16814550)
2006
22
European Federation of Neurological Societies/Peripheral Nerve Society guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy: report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society. (16643309)
2006
23
Biochemical features of chronic inflammatory demyelinating polyradiculoneuropathy]. (16585917)
2006
24
Chronic inflammatory demyelinating polyradiculoneuropathy: new views and guidelines. (16221282)
2005
25
Antibodies to peripheral nerve myelin proteins in chronic inflammatory demyelinating polyradiculoneuropathy. (15958128)
2005
26
T cell reactivity to P0, P2, PMP-22, and myelin basic protein in patients with Guillain-Barre syndrome and chronic inflammatory demyelinating polyradiculoneuropathy. (16170091)
2005
27
Chronic inflammatory demyelinating polyradiculoneuropathy: MRI study of brain and spinal cord. (15753438)
2005
28
Chronic inflammatory demyelinating polyradiculoneuropathy in patients with liver transplantation. (15372442)
2004
29
Diffuse spinal and intercostal nerve involvement in chronic inflammatory demyelinating polyradiculoneuropathy: MRI findings. (16440223)
2003
30
Chronic inflammatory demyelinating polyradiculoneuropathy in diabetic patients. (12661048)
2003
31
Proposed revised electrophysiological criteria for chronic inflammatory demyelinating polyradiculoneuropathy. (11754181)
2002
32
Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy. (11869620)
2002
33
Cardiovascular autonomic function and sympathetic skin response in chronic inflammatory demyelinating polyradiculoneuropathy. (12402289)
2002
34
Randomized controlled trial of IVIg in untreated chronic inflammatory demyelinating polyradiculoneuropathy. (11222785)
2001
35
Chronic inflammatory demyelinating polyradiculoneuropathy with histologically proven optic neuritis. (11484826)
2001
36
Treatment approaches for Guillain-BarrAc syndrome and chronic inflammatory demyelinating polyradiculoneuropathy. (11471764)
2001
37
Ataxic form of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). (10809947)
2000
38
Chronic inflammatory demyelinating polyradiculoneuropathy and severe peripheral oedema: a renal explanation. (10844803)
2000
39
Chronic inflammatory demyelinating polyradiculoneuropathy: a prevalence study in south east England. (10209187)
1999
40
Chronic inflammatory demyelinating polyradiculoneuropathy: superiority of protein A immunoadsorption over plasma exchange treatment. (10178691)
1998
41
A novel trial design to study the effect of intravenous immunoglobulin in chronic inflammatory demyelinating polyradiculoneuropathy. (8936360)
1996
42
Immunization and risk of relapse of Guillain-BarrAc syndrome or chronic inflammatory demyelinating polyradiculoneuropathy. (8761286)
1996
43
Long-term treatment of chronic inflammatory demyelinating polyradiculoneuropathy with plasma exchange or intravenous immunoglobulin. (7633875)
1995
44
Chronic inflammatory demyelinating polyradiculoneuropathy. (7921585)
1994
45
Prognosis in long-term immunosuppressive treatment of refractory chronic inflammatory demyelinating polyradiculoneuropathy. (1738011)
1992
46
Chronic inflammatory demyelinating polyradiculoneuropathy associated with Evans' syndrome. (1341469)
1992
47
Chronic inflammatory demyelinating polyradiculoneuropathy: comparison of patients with and without an associated monoclonal gammopathy. (1603342)
1992
48
Absence of antimyelin antibodies and serum demyelinating factors in most patients with chronic inflammatory demyelinating polyradiculoneuropathy. (3267485)
1988
49
Chronic nephrotoxicity complicating cyclosporine treatment of chronic inflammatory demyelinating polyradiculoneuropathy. (3796829)
1987
50
Chronic inflammatory demyelinating polyradiculoneuropathy associated with pregnancy. (3030186)
1987

Variations for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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Expression for genes affiliated with Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Search GEO for disease gene expression data for Chronic Inflammatory Demyelinating Polyradiculoneuropathy.

Pathways for genes affiliated with Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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Sources:
51PathCards, 54QIAGEN, 39NCBI BioSystems Database, 56Reactome, 61Thomson Reuters, 31KEGG, 55R&D Systems, 5Cell Signaling Technology
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Pathways related to Chronic Inflammatory Demyelinating Polyradiculoneuropathy according to GeneCards/GeneDecks:

(show all 50)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9IFNG, IFNB1
29.8CD40LG, IFNG
39.8STAT3, STAT1
49.8STAT1, STAT3
59.8STAT1, STAT3
69.7STAT3, IFNG
79.6TBX21, IFNG, STAT1
8
Show member pathways
Calcium signaling in the CD4+ TCR pathway39
9.6IFNG, TBX21, CD40LG
99.6IFNG, IFNB1, STAT1
10
Show member pathways
Transcription NF kB signaling pathway61
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response61
9.6IFNG, IFNB1, STAT1
119.6STAT1, IFNB1, IFNG
129.6STAT1, IFNB1, IFNG
139.6HLA-DRB1, MPZ, CD40LG
149.5STAT3, STAT1, IFNB1
159.5IFNG, IFNB1, HLA-DRB1
169.5MBP, MPZ, PMP22
17
Show member pathways
9.4STAT3, STAT1, IFNG
18
Show member pathways
9.4IFNG, STAT1, STAT3
19
Show member pathways
IL-2 Signaling pathway39
9.4STAT3, STAT1, IFNG
20
Show member pathways
IFN-gamma pathway39
9.4STAT3, STAT1, IFNG
219.4STAT3, STAT1, IFNG
22
Show member pathways
Development Thrombopoetin signaling via JAK STAT pathway61
9.4STAT3, STAT1, IFNG
23
Show member pathways
IL23-mediated signaling events39
Immune response IL 10 signaling pathway61
Angiopoietin receptor Tie2-mediated signaling39
Development PDGF signaling via STATs and NF kB61
Development Angiopoietin Tie2 signaling61
9.4IFNG, STAT1, STAT3
249.4STAT3, STAT1, IFNG
259.4HLA-DRB1, CXCL12, IFNG
26
Show member pathways
Immune response IL 22 signaling pathway61
G protein signaling N RAS regulation pathway61
9.4STAT1, STAT3, HLA-DRB1
279.3HLA-DRB1, STAT3, IFNG
289.3SH2D2A, STAT3, STAT1
29
Show member pathways
MAPK Cascade39
Immune response Oncostatin M signaling via MAPK in human cells61
Oncostatin M Signaling Pathway39
9.3STAT3, STAT1, MBP
309.2IFNG, IFNB1, STAT1, HLA-DRB1
31
Show member pathways
IL27-mediated signaling events39
9.2TBX21, IFNG, STAT1, STAT3
32
Show member pathways
Toll-like receptor signaling pathway39
Regulation of toll-like receptor signaling pathway39
9.2STAT3, STAT1, IFNB1, IFNG
33
Show member pathways
Type III interferon signaling39
9.2STAT3, STAT1, IFNB1, IFNG
34
Show member pathways
9.1HLA-DRB1, CXCL12, IFNG, CD40LG
359.1HLA-DRB1, STAT3, IFNG, TBX21
369.1HLA-DRB1, CXCL12, STAT3, STAT1
37
Show member pathways
9.1IFNG, STAT1, STAT3, HLA-DRB1
38
Show member pathways
Immune response IL 12 induced IFN gamma production61
8.8HLA-DRB1, STAT3, STAT1, IFNG, TBX21
39
Show member pathways
8.8IFNG, IFNB1, STAT1, STAT3, HLA-DRB1
40
Show member pathways
8.8HLA-DRB1, STAT3, STAT1, IFNB1, IFNG
41
Show member pathways
8.7CCL21, CCL19, CXCL12
42
Show member pathways
Apoptosis and survival Lymphotoxin beta receptor signaling61
8.7CXCL12, CCL19, CCL21
43
Show member pathways
8.5CD40LG, TBX21, IFNG, STAT1, STAT3, HLA-DRB1
448.4CXCL12, CCL19, CCL21, CD40LG
45
Show member pathways
8.0CXCL12, STAT3, STAT1, CCL19, CCL21
46
Show member pathways
8.0CXCL12, STAT3, STAT1, CCL19, CCL21
47
Show member pathways
8.0CCL21, CCL19, STAT1, STAT3, CXCL12
48
Show member pathways
8.0CXCL12, STAT3, STAT1, CCL19, CCL21
49
Show member pathways
7.4CXCL12, STAT3, STAT1, CCL19, CCL21, IFNB1
50
Show member pathways
7.4CXCL12, STAT3, CCL19, CCL21, IFNB1, IFNG

Compounds for genes affiliated with Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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Sources:
46Novoseek, 62Tocris Bioscience, 30IUPHAR, 12DrugBank, 52PharmGKB, 25HMDB, 3BitterDB
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Compounds related to Chronic Inflammatory Demyelinating Polyradiculoneuropathy according to GeneCards/GeneDecks:

(show top 50)    (show all 115)
idCompoundScoreTop Affiliating Genes
1indoleamine469.9IFNG, STAT1, IFNB1
2imiquimod46 62 30 1212.9IFNG, IFNB1, STAT1
3gamma globulin469.8IFNG, CD40LG, ALB
4mezerein469.7MBP, IFNG, IFNB1
5l-tryptophan52 30 46 25 1213.7IFNG, ALB, IFNB1
62,5-oligoadenylate469.7STAT1, IFNB1, IFNG
7valsartan46 62 30 1212.7STAT1, ALB, STAT3
8cerebrosides469.6MPZ, MBP
9polyinosinic-polycytidylic acid469.6IFNG, IFNB1, STAT1, STAT3
10ganglioside469.5PMP22, MPZ, MBP, CD40LG
11endotoxin469.5STAT1, CD40LG, IFNG, IFNB1
12herbimycin a46 6210.4STAT1, CD40LG, CXCL12, IFNB1, IFNG
13ribavirin46 52 1211.3STAT3, STAT1, IFNB1, IFNG, CD40LG
14poly(i-c)469.3IFNB1, IFNG, STAT1
15ifn-alpha469.3STAT1, IFNG, STAT3, CXCL12, IFNB1
165-aza-2deoxycytidine469.3CXCL12, IFNG, IFNB1, STAT1, STAT3
17imatinib46 52 1211.2CXCL12, ALB, STAT1, STAT3
18sb 20358046 6210.2CXCL12, IFNB1, IFNG, STAT1, STAT3
19glatiramer acetate46 1210.2IFNB1, HLA-DRB1, IFNG, MBP, MPZ
20rapamycin469.1CXCL12, IFNG, STAT1, STAT3, CD40LG
21teck469.1CXCL12, CCL19, CCL21
22larc469.1CCL19, CXCL12, CCL21
23mip-3beta469.0CCL21, CCL19
24ivig469.0MBP, ALB, IFNG, IFNB1, CD40LG
25actinomycin d469.0CD40LG, IFNB1, STAT1, STAT3, CXCL12, IFNG
26genistein46 30 62 3 25 1214.0IFNG, CD40LG, IFNB1, STAT1, STAT3, CXCL12
27cyclosporin a46 30 6210.9IFNG, MBP, CD40LG, STAT1, STAT3
28cisplatin46 52 62 1211.9STAT3, CD40LG, IFNB1, MBP, STAT1
29dexamethasone46 52 30 1211.9CXCL12, IFNG, IFNB1, STAT1, CD40LG, STAT3
30methotrexate52 46 1210.9ALB, IFNB1, HLA-DRB1, MBP
31cholesterol46 30 25 1211.9MPZ, CXCL12, STAT1, IFNB1, STAT3, ALB
32creatinine468.8IFNB1, ALB, CD40LG, MBP, MPZ
33thymidine46 259.8CXCL12, STAT3, IFNB1, IFNG, MBP
34glutamate468.7CD40LG, IFNB1, CXCL12, MBP, HLA-DRB1, MPZ
35indomethacin46 30 62 1211.7STAT1, CD40LG, MBP, IFNB1, IFNG, ALB
36cycloheximide468.7STAT1, IFNB1, MBP, CXCL12, STAT3, IFNG
37heparin46 30 25 1211.6MBP, ALB, IFNB1, CXCL12, STAT3, CD40LG
38tarc468.5CCL19, IFNB1, IFNG, CCL21, CXCL12
39ccl346 309.5IFNG, CCL21, CXCL12, IFNB1, CCL19
40retinoic acid46 259.5CD40LG, PMP22, IFNG, STAT1, STAT3, MBP
41aspartate468.5CD40LG, STAT3, PMP22, MPZ, IFNB1, ALB
42estrogen468.4CXCL12, STAT3, MBP, STAT1, CD40LG, IFNB1
43vegf468.4SH2D2A, IFNG, IFNB1, CD40LG, STAT3, CXCL12
44alanine468.4IFNB1, HLA-DRB1, CD40LG, MBP, ALB, STAT3
45serine468.3STAT1, STAT3, CXCL12, IFNB1, MBP, CD40LG
46tyrosine467.9STAT3, HLA-DRB1, SH2D2A, MBP, IFNB1, STAT1
47arginine467.9HLA-DRB1, PMP22, MPZ, CXCL12, CD40LG, MBP
48cysteine467.8CD40LG, MBP, ALB, STAT1, STAT3, MPZ
49rantes467.6CXCL12, CCL21, IFNB1, STAT1, IFNG, CCL19
50pge2467.6CD40LG, IFNG, IFNB1, CCL21, CCL19, STAT1

GO Terms for genes affiliated with Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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Sources:
17Gene Ontology
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Cellular components related to Chronic Inflammatory Demyelinating Polyradiculoneuropathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1compact myelinGO:0432189.4MBP, PMP22
2external side of plasma membraneGO:0098979.0HLA-DRB1, CXCL12, IFNG, CD40LG
3extracellular regionGO:0055767.6CCL19, CCL21, IFNB1, IFNG, ALB, CXCL12
4extracellular spaceGO:0056157.3CD40LG, ALB, IFNG, IFNB1, CCL21, CCL19

Biological processes related to Chronic Inflammatory Demyelinating Polyradiculoneuropathy according to GeneCards/GeneDecks:

(show all 31)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of metanephric nephron tubule epithelial cell differentiationGO:07230810.2IFNG, STAT1
2positive regulation of isotype switching to IgG isotypesGO:04830410.2IFNG, TBX21
3negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:00334010.2STAT1, IFNG
4regulation of interferon-gamma-mediated signaling pathwayGO:06033410.1IFNG, STAT1
5positive regulation of peptidyl-serine phosphorylation of STAT proteinGO:03314110.0IFNB1, IFNG
6JAK-STAT cascade involved in growth hormone signaling pathwayGO:0603979.9STAT1, STAT3
7response to exogenous dsRNAGO:0433309.9IFNB1, STAT1
8regulation of type I interferon-mediated signaling pathwayGO:0603389.8IFNB1, STAT1
9defense response to virusGO:0516079.8STAT1, IFNB1, IFNG
10interferon-gamma-mediated signaling pathwayGO:0603339.8IFNG, STAT1, HLA-DRB1
11JAK-STAT cascadeGO:0072599.8STAT1, STAT3
12positive regulation of interleukin-1 beta secretionGO:0507189.7CCL19, IFNG
13B cell proliferationGO:0421009.6CD40LG, IFNB1
14positive regulation of interleukin-12 productionGO:0327359.6CCL19, IFNG, CD40LG
15positive regulation of glycoprotein biosynthetic processGO:0105609.4CCL19, CCL21
16immunological synapse formationGO:0017719.4CCL21, CCL19
17establishment of T cell polarityGO:0017689.4CCL19, CCL21
18response to prostaglandin EGO:0346959.4CCL19, CCL21
19positive regulation of dendritic cell antigen processing and presentationGO:0026069.3CCL21, CCL19
20positive regulation of cell motilityGO:20001479.3CCL21, CCL19
21positive regulation of chemotaxisGO:0509219.3CCL21, CCL19
22positive regulation of receptor-mediated endocytosisGO:0482609.3CCL19, CCL21
23dendritic cell chemotaxisGO:0024079.3CCL21, CCL19
24positive regulation of neutrophil chemotaxisGO:0900239.3CCL19, CCL21
25cytokine-mediated signaling pathwayGO:0192219.2HLA-DRB1, STAT3, STAT1, IFNB1, IFNG
26positive regulation of phosphatidylinositol 3-kinase activityGO:0435529.1CCL21, CCL19
27negative regulation of leukocyte apoptotic processGO:20001079.1CXCL12, CCL19, CCL21
28release of sequestered calcium ion into cytosolGO:0512099.1CCL19, CCL21
29response to virusGO:0096159.1TBX21, IFNG, IFNB1, CCL19, CXCL12
30T cell costimulationGO:0312959.0CCL21, CCL19, HLA-DRB1
31immune responseGO:0069558.2MBP, CCL21, CCL19, CXCL12, HLA-DRB1

Molecular functions related to Chronic Inflammatory Demyelinating Polyradiculoneuropathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:0051649.9CD40LG, STAT1
2CCR5 chemokine receptor bindingGO:0317309.7STAT1, STAT3
3cytokine activityGO:0051259.3CD40LG, IFNG, IFNB1
4CCR7 chemokine receptor bindingGO:0317329.1CCL21, CCL19
5chemokine receptor bindingGO:0423798.8CCL21, CCL19, CXCL12
6chemokine activityGO:0080098.7CXCL12, CCL19, CCL21

Products for genes affiliated with Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet