MCID: CHR067
MIFTS: 22

Chronic Intestinal Vascular Insufficiency

Categories: Gastrointestinal diseases, Cardiovascular diseases

Aliases & Classifications for Chronic Intestinal Vascular Insufficiency

MalaCards integrated aliases for Chronic Intestinal Vascular Insufficiency:

Name: Chronic Intestinal Vascular Insufficiency 12 14
Chronic Mesenteric Ischemia 12 69
Cmi - Chronic Mesenteric Ischaemia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8633
ICD9CM 35 557.1
UMLS 69 C0311262

Summaries for Chronic Intestinal Vascular Insufficiency

MalaCards based summary : Chronic Intestinal Vascular Insufficiency, also known as chronic mesenteric ischemia, is related to ileocolitis and mesenteric artery ischemia, and has symptoms including abdominal angina An important gene associated with Chronic Intestinal Vascular Insufficiency is NCR3 (Natural Cytotoxicity Triggering Receptor 3), and among its related pathways/superpathways are Ferroptosis and Fatty Acid Biosynthesis (WikiPathways).

Related Diseases for Chronic Intestinal Vascular Insufficiency

Diseases related to Chronic Intestinal Vascular Insufficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
id Related Disease Score Top Affiliating Genes
1 ileocolitis 29.4 ATP12A ATP4A
2 mesenteric artery ischemia 11.1
3 scrotum melanoma 10.1 ATP12A ATP4A
4 congenital aphakia 10.1 ATP12A ATP4A
5 shwartzman phenomenon 10.1 ATP12A ATP4A
6 primary syphilis 10.1 ATP12A ATP4A
7 bone giant cell sarcoma 10.1 ATP12A ATP4A
8 ischemia 10.1
9 urethral calculus 10.1 ATP12A ATP4A
10 breast ductal adenoma 10.1 ATP12A ATP4A
11 hypopituitarism 10.1 ATP12A ATP4A
12 amyotrophic lateral sclerosis type 5 10.1 ATP12A ATP4A
13 abnormal pupillary function 10.1 ATP12A ATP4A
14 atheroembolism of kidney 10.1 ATP12A ATP4A
15 microphthalmia, syndromic 12 10.1 ATP12A ATP4A
16 synostosis 10.1 ATP12A ATP4A
17 muscle cancer 10.0 ATP12A ATP4A
18 adult xanthogranuloma 10.0 ATP12A ATP4A
19 polysyndactyly with cardiac malformation 10.0 ATP12A ATP4A
20 focal hand dystonia 10.0 ATP12A ATP4A
21 cloacal exstrophy 10.0 ATP12A ATP4A
22 thrombocytopenia due to platelet alloimmunization 10.0 ATP12A ATP4A
23 proliferative fasciitis 10.0 ATP12A ATP4A
24 bladder neck cancer 10.0 ATP12A ATP4A
25 spinocerebellar ataxia 18 10.0 ATP12A ATP4A
26 intracranial sinus thrombosis 10.0 ATP12A ATP4A
27 fungal gastritis 10.0 ATP12A ATP4A
28 cubitus valgus with mental retardation and unusual facies 9.9 ATP12A ATP4A
29 villous adenocarcinoma 9.9 ATP12A ATP4A
30 allergic urticaria 9.9 ATP12A ATP4A
31 mesenteric vascular occlusion 9.9 ATP12A ATP4A
32 scleral staphyloma 9.8 ATP12A ATP4A SPAG7
33 anterior cerebral artery infarction 9.8 ATP12A ATP4A
34 pediatric infratentorial ependymoblastoma 9.8 ATP12A ATP4A
35 hepatic veno-occlusive disease 9.8 ATP12A ATP4A
36 frontal sinus schneiderian papilloma 9.7 ATP12A ATP4A
37 fibrosarcomatous osteosarcoma 9.7 ATP12A ATP4A
38 hepatitis 9.7
39 gastric ulcer 9.7
40 cholecystitis 9.7
41 acalculous cholecystitis 9.7
42 gastric dilatation 9.7
43 aortic disease 9.7
44 median arcuate ligament syndrome 9.7
45 fibromuscular dysplasia 9.7
46 prostatic cyst 9.6 ATP12A ATP4A
47 gnathomiasis 9.4 ATP12A ATP4A
48 hodgkin's paragranuloma 5.7 ACSL5 ACSL6 ATP12A ATP4A DYNLL1 GPI

Graphical network of the top 20 diseases related to Chronic Intestinal Vascular Insufficiency:



Diseases related to Chronic Intestinal Vascular Insufficiency

Symptoms & Phenotypes for Chronic Intestinal Vascular Insufficiency

UMLS symptoms related to Chronic Intestinal Vascular Insufficiency:


abdominal angina

Drugs & Therapeutics for Chronic Intestinal Vascular Insufficiency

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Investigation of Chronic Intestinal Ischemia Recruiting NCT02914912 Phase 1, Phase 2

Search NIH Clinical Center for Chronic Intestinal Vascular Insufficiency

Genetic Tests for Chronic Intestinal Vascular Insufficiency

Anatomical Context for Chronic Intestinal Vascular Insufficiency

Publications for Chronic Intestinal Vascular Insufficiency

Variations for Chronic Intestinal Vascular Insufficiency

Expression for Chronic Intestinal Vascular Insufficiency

Search GEO for disease gene expression data for Chronic Intestinal Vascular Insufficiency.

Pathways for Chronic Intestinal Vascular Insufficiency

Pathways related to Chronic Intestinal Vascular Insufficiency according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.76 ACSL5 ACSL6
2 10.3 ACSL5 ACSL6
3 9.74 ACSL5 ACSL6

GO Terms for Chronic Intestinal Vascular Insufficiency

Biological processes related to Chronic Intestinal Vascular Insufficiency according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 mesoderm formation GO:0001707 9.26 GPI WLS
2 long-chain fatty acid metabolic process GO:0001676 9.16 ACSL5 ACSL6
3 long-chain fatty-acyl-CoA biosynthetic process GO:0035338 8.96 ACSL5 ACSL6
4 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.62 ATP12A ATP4A

Molecular functions related to Chronic Intestinal Vascular Insufficiency according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 long-chain fatty acid-CoA ligase activity GO:0004467 9.26 ACSL5 ACSL6
2 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP12A ATP4A
3 decanoate--CoA ligase activity GO:0102391 8.96 ACSL5 ACSL6
4 hydrogen:potassium-exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Chronic Intestinal Vascular Insufficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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