MCID: CHR064
MIFTS: 42

Chronic Monocytic Leukemia malady

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Chronic Monocytic Leukemia

Aliases & Descriptions for Chronic Monocytic Leukemia:

Name: Chronic Monocytic Leukemia 12 14
Leukemia, Monocytic, Chronic 69
Leukemia, Myeloid 42

Classifications:



External Ids:

Disease Ontology 12 DOID:8593
ICD10 33 C93.1
ICD9CM 35 206.1
MeSH 42 D007951
NCIt 47 C34774
UMLS 69 C0023466

Summaries for Chronic Monocytic Leukemia

MalaCards based summary : Chronic Monocytic Leukemia, also known as leukemia, monocytic, chronic, is related to myeloid leukemia and leukemia, chronic myeloid, somatic. An important gene associated with Chronic Monocytic Leukemia is C3 (Complement C3), and among its related pathways/superpathways are Sertoli-Sertoli Cell Junction Dynamics and Focal Adhesion. The drugs Dexamethasone and Cyclosporine have been mentioned in the context of this disorder. Affiliated tissues include monocytes and myeloid, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and hematopoietic system

Related Diseases for Chronic Monocytic Leukemia

Diseases in the Monocytic Leukemia family:

Acute Monocytic Leukemia Adult Acute Monocytic Leukemia
Chronic Monocytic Leukemia Subacute Monocytic Leukemia

Diseases related to Chronic Monocytic Leukemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
id Related Disease Score Top Affiliating Genes
1 myeloid leukemia 11.5
2 leukemia, chronic myeloid, somatic 11.0
3 atypical chronic myeloid leukemia 11.0
4 myeloid/lymphoid or mixed lineage leukemia 11.0
5 leukemia, acute myeloid 10.9
6 cyclotropia 10.2 C3 MPO
7 dermatomycosis 10.2 C3 MPO
8 adult spinal cord ependymoma 10.2 CD34 MPO
9 omsk hemorrhagic fever 10.2 ITGAM MPO
10 freemartinism 10.2 CD34 PTPRC
11 rectum leiomyoma 10.2 F2 PTPRC
12 dermoid cyst 10.2 CD34 PTEN
13 dislocation of ear ossicle 10.2 C3 MPO
14 heel spur 10.2 CD34 PTPRC
15 rhabdoid cancer 10.1 CD34 PTPRC
16 demyelinating disease 10.1 CD34 PTEN
17 laryngeal adenoid cystic carcinoma 10.1 CD34 PTPRC
18 geniculate herpes zoster 10.1 CD34 PTPRC
19 hemopneumothorax 10.1 CD34 F2
20 choriocarcinoma of ovary 10.1 CD34 PTPRC
21 bone leiomyosarcoma 10.1 CD34 PTPRC
22 atrophic vulva 10.1 C3 F2 MPO
23 cerebral arterial disease 10.1 CD34 PTPRC
24 neurofibromatosis 10.1 MPO PTPRC
25 tubular adenocarcinoma 10.1 CD34 F2
26 grix blankenship peterson syndrome 10.1 ITGAM MPO
27 macrodactyly of the foot 10.0 ITGAM ITGAX
28 malignant testicular leydig cell tumor 10.0 CD34 MPO
29 leukemia 10.0
30 monocytic leukemia 10.0
31 immune-complex glomerulonephritis 10.0 C3 MPO
32 proctitis 10.0 CD34 F2 PTEN
33 myocardial infarction 9.8 CD34 F2 ITGAM MPO
34 cranioectodermal dysplasia 1 9.6 CD34 ITGAM ITGAX MPO PTPRC
35 hodgkin's lymphoma, lymphocytic depletion 8.6 C3 CD34 F2 ITGAD ITGAM ITGAX

Graphical network of the top 20 diseases related to Chronic Monocytic Leukemia:



Diseases related to Chronic Monocytic Leukemia

Symptoms & Phenotypes for Chronic Monocytic Leukemia

GenomeRNAi Phenotypes related to Chronic Monocytic Leukemia according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-109 9.44 PTPRC
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-112 9.44 ITGAM
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-116 9.44 ITGAM
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-119 9.44 PTPRC
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-165 9.44 PTPRC
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-213 9.44 PTPRC
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-66 9.44 PTEN
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.44 PTPRC
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 9.44 F2
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-87 9.44 PTPRC F2 ITGAM PTEN

MGI Mouse Phenotypes related to Chronic Monocytic Leukemia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.81 C3 CD34 F2 ITGAD ITGAM ITGAX
2 homeostasis/metabolism MP:0005376 9.61 C3 CD34 F2 ITGAD ITGAM LGALS1
3 immune system MP:0005387 9.32 PTEN PTPRC C3 CD34 F2 ITGAD

Drugs & Therapeutics for Chronic Monocytic Leukemia

Drugs for Chronic Monocytic Leukemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 677)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-02-2 5743
2
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 79217-60-0, 59865-13-3 5284373 6435893
3
Mitoxantrone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 65271-80-9 4212
4
Daunorubicin Approved Phase 4,Phase 2,Phase 3,Phase 1 20830-81-3 30323
5
Etoposide Approved Phase 4,Phase 3,Phase 2,Phase 1 33419-42-0 36462
6
Idarubicin Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 58957-92-9 42890
7
Topotecan Approved, Investigational Phase 4,Phase 2,Phase 1 119413-54-6, 123948-87-8 60700
8
Cytarabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 147-94-4 6253
9
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
10
Amsacrine Approved Phase 4,Phase 3,Phase 1,Phase 2 51264-14-3 2179
11
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
12
Dasatinib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 302962-49-8 3062316
13
Fludarabine Approved Phase 4,Phase 3,Phase 2,Phase 1 21679-14-1, 75607-67-9 30751
14
Vidarabine Approved Phase 4,Phase 3,Phase 2,Phase 1 24356-66-9 32326 21704
15
Busulfan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 55-98-1 2478
16
Histamine Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 75614-87-8, 51-45-6 774
17
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 22916-47-8 4189
18
Thiotepa Approved Phase 4,Phase 3,Phase 2,Phase 1 52-24-4 5453
19
Lenograstim Approved Phase 4,Phase 3,Phase 2,Phase 1 135968-09-1
20
Lenalidomide Approved Phase 4,Phase 3,Phase 2,Phase 1 191732-72-6 216326
21
Azacitidine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 320-67-2 9444
22
Decitabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 2353-33-5 451668
23
Aldesleukin Approved Phase 4,Phase 3,Phase 2,Phase 1 85898-30-2, 110942-02-4
24
Arsenic trioxide Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 1327-53-3 518740
25
Nicotine Approved Phase 4 54-11-5 942 89594
26
Sorafenib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 284461-73-0 216239 406563
27
Posaconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 171228-49-2 147912
28
Benzocaine Approved Phase 4,Phase 2,Phase 3,Phase 1 1994-09-7, 94-09-7 2337
29
Micafungin Approved, Investigational Phase 4,Phase 2 235114-32-6 3081921 477468
30
Tretinoin Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 302-79-4 5538
31
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 59-30-3 6037
32
Niacin Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 59-67-6 938
33
Vitamin C Approved, Nutraceutical Phase 4,Phase 2,Phase 1 50-81-7 5785 54670067
34
Nicotinamide Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 98-92-0 936
35 tannic acid Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Phase 1
36
Aclarubicin Investigational Phase 4,Phase 2,Phase 1 57576-44-0 451415
37
Histamine Phosphate Phase 4,Phase 3,Phase 1,Phase 2 51-74-1 65513
38 Dexamethasone acetate Phase 4,Phase 3,Phase 2,Phase 1 1177-87-3
39 Imatinib Mesylate Phase 4,Phase 3,Phase 2,Phase 1 123596
40 Interleukin-2 Phase 4,Phase 3,Phase 2,Phase 1
41 interferons Phase 4,Phase 3,Phase 2,Phase 1
42 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
43 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
44 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
45 topoisomerase I inhibitors Phase 4,Phase 2,Phase 1
46 Adjuvants, Immunologic Phase 4,Phase 3,Phase 2,Phase 1
47 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
48 Neurotransmitter Agents Phase 4,Phase 3,Phase 1,Phase 2
49 Gemtuzumab Phase 4,Phase 2,Phase 3,Phase 1
50 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 2988)
id Name Status NCT ID Phase
1 Idarubicin at Different Dosages as Induction Therapy for Newly Diagnosed Acute Myeloid Leukaemia Unknown status NCT02277847 Phase 4
2 AML1-ETO Acute Myeloid Leukemia With Fludarabine and Cytarabine Chemotherapy Unknown status NCT02024308 Phase 4
3 3 Anthracyclines, 2 Types of Consolidation With Different ARA-C Doses and Maintenance in Adult Acute Myeloid Leukemia Unknown status NCT01587430 Phase 4
4 Compliance: Role Emerges for Success in Chronic Myelogenous Leukaemia (CML): Evaluation aND Optimisation Unknown status NCT01243489 Phase 4
5 Decitabine for Myelodysplastic Syndromes and Acute Myeloid Leukemia Before Allogeneic Hematopoietic Cell Transplantation Unknown status NCT01806116 Phase 4
6 Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission Unknown status NCT01901666 Phase 4
7 Efficacy of G-CSF-Priming in Elderly AML Patients Unknown status NCT00199147 Phase 4
8 AIDA2000 - Risk-Adapted Therapy for Patients With Acute Promyelocytic Leukemia Unknown status NCT00180128 Phase 4
9 Treatment Protocol for Relapsed Acute Promyelocytic Leukemia (APL) With Arsenic Unknown status NCT00196768 Phase 4
10 Study to Evaluate Nilotinib in Chronic Myelogenous Leukemia (CML) Patients With SubOptimal Response Completed NCT01043874 Phase 4
11 Fludarabine, Cytarabine, Topotecan in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia Completed NCT00488709 Phase 4
12 Glivec® (Imatinib Mesylate, STI571) in Monotherapy Versus Glivec®-Interferon Alpha in the Treatment of Chronic-Phase Chronic Myeloid Leukaemia Completed NCT00390897 Phase 4
13 Study of Oral AMN107 (Nilotinib) in Adult Patients With Imatinib - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase Previously Enrolled to CAMN107A2109 Trial Completed NCT01368523 Phase 4
14 Study of Molecular Response in Adult Patients on Nilotinib With Philadelphia Chromosome Positive Chronic Myelogenous Leukemia (Ph+ CML) in Chronic Phase and a Suboptimal Molecular Response to Imatinib Completed NCT00644878 Phase 4
15 Study of Treatment With Nilotinib in Adult Patients With Imatinib - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase Completed NCT00786812 Phase 4
16 Phase IV, Open-label, Multicenter Study of Dasatinib in Chronic-Phase Chronic Myeloid Leukemia (CP-CML) Patients With Chronic, Low-grade Non-Hematologic Toxicity to Imatinib Completed NCT01660906 Phase 4
17 LAM07: Study to Analyze the Efficacy of a Risk Adapted Treatment Strategy, Including Gemtuzumab Ozogamicin (GO) During Consolidation, for Patients With Acute Myeloid Leukemia (AML) Completed NCT01041040 Phase 4
18 AML2003 - Standard-Therapy vs Intensified Therapy for Adult Acute Myeloid Leukemia Patients <= 60 Years Completed NCT00180102 Phase 4
19 An Exploratory Trial to Assess the Improvement of Adverse Events in Chronic Myelogenous Leukemia Patients Treated With Imatinib When Switched to Nilotinib Treatment Completed NCT00980018 Phase 4
20 Study Comparing Standard Dose and High-dose Imatinib Mesylate in Patients With Chronic Phase Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia (CML) Completed NCT00171899 Phase 4
21 Gleevec Trial in Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia Completed NCT00081926 Phase 4
22 Maintenance Therapy With Ceplene® (Histamine) and IL-2 on Immune Response and MRD in Acute Myeloid Leukemia Completed NCT01347996 Phase 4
23 CMR Rate of Newly Diagnosed CML-CP Patients Treated With Nilotinib Completed NCT01227577 Phase 4
24 AML96 - Risk-Adapted and Randomized Postremission-Therapy for Adult Acute Myeloid Leukemia Patients Completed NCT00180115 Phase 4
25 Glivec in Pediatric Chronic Myeloid Leukemia (CML) Completed NCT00845221 Phase 4
26 Therapy of Acute Myeloid Leukemia in Patients Over the Age of 60 : DA Versus Mitoxantrone With Intermittent AraC Completed NCT00180167 Phase 4
27 Study Evaluating Mylotarg (Gemtuzumab Ozogamicin) in Usual Care Completed NCT00161668 Phase 4
28 Nilotinib in Newly Diagnosed Adult Philadelphia Chromosome & /or BCR-ABL Positive Chronic Myeloid Leukaemia in Chronic Phase Completed NCT01061177 Phase 4
29 Study Evaluating the Effect of Corticosteroids on Mylotarg® Infusion-Related Adverse Events in Patients With Leukemia Completed NCT00304447 Phase 4
30 Tasigna in Glivec-resistant or Intolerant Patients in CML Completed NCT01206088 Phase 4
31 Oral Posaconazole in High Risk Patients With Gastrointestinal Dysfunction (Study P05115) Completed NCT00686543 Phase 4
32 Treatment of the Acute Myeloblastic Leukaemia in Patients Over 65 Years Completed NCT00464217 Phase 4
33 Treatment of Acute Myeloblastic Leukemia in Younger Patients Completed NCT00390715 Phase 4
34 Treatment of Relapsed Promyelocytic Leukemia With Arsenic Trioxide (ATO) Completed NCT00504764 Phase 4
35 Treatment of Acute Promyelocytic Leukemia With All-Trans Retinoic Acid (ATRA) and Idarubicin (AIDA) Completed NCT00465933 Phase 4
36 Treatment of Newly Diagnosed Patients With Acute Promyelocytic Leukemia (PETHEMA LPA 2005) Completed NCT00408278 Phase 4
37 A Study for Dacogen Treatment in Patients With Myelodysplastic Syndrome Completed NCT01041846 Phase 4
38 Bone Marrow Transplantation in Treating Patients With Hematologic Cancer Completed NCT00003398 Phase 4
39 SMD_FLAG-IDA_98: FLAG-IDA in Induction Treatment of High Risk Myelodysplastic Syndromes or Secondary Acute Myeloblastic Leukemia Completed NCT00487448 Phase 4
40 Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking Completed NCT00365508 Phase 4
41 Safety And Efficacy Study Of Bosutinib In Patients With Philadelphia Chromosome Positive Chronic Myeloid Leukemia Previously Treated With One Or More Tyrosine Kinase Inhibitors Recruiting NCT02228382 Phase 4
42 Therapy of Early Chronic Phase Chronic Myelogenous Leukemia (CML) With Dasatinib Recruiting NCT02689440 Phase 4
43 Sorafenib for Prophylaxis of Leukemia Relapse in Allo-HSCT Recipients With FLT3-ITD Positive AML Recruiting NCT02474290 Phase 4
44 Early Tapering of Immunosuppressive Agents to Immunomodulation to Improve Survival of AML Patients Recruiting NCT03150134 Phase 4
45 Fludarabine and Cytarabine Versus High-dose Cytarabine for CBF-AML Recruiting NCT02926586 Phase 4
46 Interferon for the Intervention of Molecular Relapse in t (8; 21) AML After Allo-HSCT Recruiting NCT02027064 Phase 4
47 Study Assessing Deep Molecular Response in Adult Patients With CML in Chronic Phase Treated With Nilotinib Firstline. Recruiting NCT02546674 Phase 4
48 Efficacy and Safety of rhTPO for the Treatment of Thrombocytopenia After Chemotherapy in AML Patients Recruiting NCT02267993 Phase 4
49 Pharmacokinetics of Posaconazole (Noxafil®) as Prophylaxis for Invasive Fungal Infections Recruiting NCT02805946 Phase 4
50 Identification of New Immune Factors Specific of Relapse in Childhood B Lineage Acute Lymphoblastic Leukemia Recruiting NCT02618109 Phase 4

Search NIH Clinical Center for Chronic Monocytic Leukemia

Cochrane evidence based reviews: leukemia, myeloid

Genetic Tests for Chronic Monocytic Leukemia

Anatomical Context for Chronic Monocytic Leukemia

MalaCards organs/tissues related to Chronic Monocytic Leukemia:

39
Monocytes, Myeloid

Publications for Chronic Monocytic Leukemia

Articles related to Chronic Monocytic Leukemia:

id Title Authors Year
1
Partial cytogenetic response with toceranib and prednisone treatment in a young dog with chronic monocytic leukemia. ( 23995854 )
2013
2
BCR-ABL translocation in a dog with chronic monocytic leukemia. ( 21143615 )
2011
3
Chronic monocytic leukemia terminating in blastic transformation. ( 3465380 )
1986
4
Chronic monocytic leukemia in adults. ( 6945897 )
1981
5
Chronic monocytic leukemia. ( 276262 )
1978
6
Chronic monocytic leukemia: a case with an eight-year survival. ( 5240097 )
1967
7
Chronic monocytic leukemia in childhood. ( 13576375 )
1958

Variations for Chronic Monocytic Leukemia

Expression for Chronic Monocytic Leukemia

Search GEO for disease gene expression data for Chronic Monocytic Leukemia.

Pathways for Chronic Monocytic Leukemia

Pathways related to Chronic Monocytic Leukemia according to GeneCards Suite gene sharing:

(show all 21)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.68 ITGAD ITGAM ITGAX PTEN
2
Show member pathways
12.65 ITGAD ITGAM ITGAX PTEN
3
Show member pathways
12.62 ITGAD ITGAM ITGAX PTEN
4 12.34 F2 ITGAD ITGAM ITGAX
5 12.23 CD34 LGALS1 MPO PTPRC
6
Show member pathways
12.18 ITGAD ITGAM ITGAX
7
Show member pathways
12 F2 ITGAM ITGAX
8 11.99 C3 ITGAM ITGAX
9 11.91 C3 ITGAM MPO
10
Show member pathways
11.89 ITGAD ITGAM ITGAX
11 11.85 CD34 ITGAM PTPRC
12
Show member pathways
11.8 C3 ITGAM ITGAX
13 11.78 ITGAD ITGAM ITGAX PTEN
14 11.7 ITGAD ITGAM ITGAX
15 11.7 C3 F2 ITGAM ITGAX
16 11.62 CD34 ITGAM PTPRC
17 11.48 CD34 ITGAM PTPRC
18 11.39 C3 ITGAD ITGAM ITGAX
19 11.29 ITGAD ITGAM ITGAX
20 11.14 CD34 ITGAM ITGAX PTPRC
21 11.09 CD34 ITGAM ITGAX MPO PTPRC

GO Terms for Chronic Monocytic Leukemia

Cellular components related to Chronic Monocytic Leukemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.46 CD34 F2 ITGAX PTPRC
2 integrin complex GO:0008305 9.13 ITGAD ITGAM ITGAX
3 cell surface GO:0009986 9.1 CD34 ITGAD ITGAM ITGAX LGALS1 PTPRC

Biological processes related to Chronic Monocytic Leukemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.71 CD34 ITGAD ITGAM ITGAX
2 cellular protein metabolic process GO:0044267 9.54 C3 F2 LGALS1
3 extracellular matrix organization GO:0030198 9.5 ITGAD ITGAM ITGAX
4 integrin-mediated signaling pathway GO:0007229 9.33 ITGAD ITGAM ITGAX
5 heterotypic cell-cell adhesion GO:0034113 9.26 ITGAD ITGAX
6 leukocyte migration GO:0050900 9.26 CD34 F2 ITGAM ITGAX
7 neutrophil degranulation GO:0043312 9.02 C3 ITGAM ITGAX MPO PTPRC

Sources for Chronic Monocytic Leukemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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