MCID: CHR466
MIFTS: 35

Chronic Thromboembolic Pulmonary Hypertension malady

Respiratory diseases, Rare diseases, Blood diseases categories

Aliases & Classifications for Chronic Thromboembolic Pulmonary Hypertension

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Sources:
47Orphanet, 60UMLS, 61UMLS via Orphanet
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Chronic Thromboembolic Pulmonary Hypertension, Aliases & Descriptions:

Name: Chronic Thromboembolic Pulmonary Hypertension 47 60
 
Cteph 47


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Respiratory diseases, Blood diseases


Characteristics (Orphanet epidemiological data):

47
chronic thromboembolic pulmonary hypertension:
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: Adult


External Ids:

Orphanet47 70591
UMLS via Orphanet61 C2363973

Summaries for Chronic Thromboembolic Pulmonary Hypertension

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MalaCards based summary: Chronic Thromboembolic Pulmonary Hypertension, also known as cteph, is related to pulmonary hypertension and dysfibrinogenemia. An important gene associated with Chronic Thromboembolic Pulmonary Hypertension is NFKBIL1 (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1), and among its related pathways are Response to elevated platelet cytosolic Ca2+ and Cell adhesion ECM remodeling. The compounds batroxobin and sucralfate have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and endothelial.

Related Diseases for Chronic Thromboembolic Pulmonary Hypertension

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Graphical network of the top 20 diseases related to Chronic Thromboembolic Pulmonary Hypertension:



Diseases related to chronic thromboembolic pulmonary hypertension

Symptoms for Chronic Thromboembolic Pulmonary Hypertension

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Drugs & Therapeutics for Chronic Thromboembolic Pulmonary Hypertension

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Drug clinical trials:

Search ClinicalTrials for Chronic Thromboembolic Pulmonary Hypertension

Search NIH Clinical Center for Chronic Thromboembolic Pulmonary Hypertension

Genetic Tests for Chronic Thromboembolic Pulmonary Hypertension

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Anatomical Context for Chronic Thromboembolic Pulmonary Hypertension

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MalaCards organs/tissues related to Chronic Thromboembolic Pulmonary Hypertension:

31
Lung, Heart, Endothelial, Brain, Lymph node, Spleen, Smooth muscle, Testes, Monocytes, Neutrophil

Animal Models for Chronic Thromboembolic Pulmonary Hypertension or affiliated genes

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Publications for Chronic Thromboembolic Pulmonary Hypertension

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Articles related to Chronic Thromboembolic Pulmonary Hypertension:

(show top 50)    (show all 415)
idTitleAuthorsYear
1
Balloon pulmonary angioplasty using contrast agents improves impaired renal function in patients with chronic thromboembolic pulmonary hypertension. (25880583)
2015
2
Recent advances of pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension including Japanese experiences. (24068659)
2014
3
Operability Assessment and Postoperative Outcome in Chronic Thromboembolic Pulmonary Hypertension. (24401572)
2014
4
Dual-energy CT perfusion and angiography in chronic thromboembolic pulmonary hypertension: diagnostic accuracy and concordance with radionuclide scintigraphy. (23982287)
2014
5
Balloon pulmonary angioplasty in patients with inoperable chronic thromboembolic pulmonary hypertension. (23846611)
2013
6
Clinical outcomes of thromboendarterectomy for chronic thromboembolic pulmonary hypertension: 12-year experience. (23423163)
2013
7
Optical coherence tomography is superior to intravascular ultrasound for diagnosis of distal-type chronic thromboembolic pulmonary hypertension. (23386271)
2013
8
Right ventricular longitudinal deformation parameters and exercise capacity : Prognosis of patients with chronic thromboembolic pulmonary hypertension. (23740084)
2013
9
Chronic thromboembolic pulmonary hypertension due to upper-extremity deep vein thrombosis caused by thoracic outlet syndrome. (22138476)
2012
10
Evolving surgical techniques for pulmonary endarterectomy according to the changing features of chronic thromboembolic pulmonary hypertension patients during 17-year single-center experience. (22498087)
2012
11
Characterization of proximal pulmonary arterial cells from chronic thromboembolic pulmonary hypertension patients. (22452949)
2012
12
Chronic thromboembolic pulmonary hypertension with pulmonary infarction occuring in a hypertensive. (21970224)
2011
13
Clinical course of unoperated mild chronic thromboembolic pulmonary hypertension. (21594826)
2011
14
The incidence of recurrent venous thromboembolism and chronic thromboembolic pulmonary hypertension following a first episode of pulmonary embolism. (21743331)
2011
15
Surgical outcome of two difficult cases with predominant proximal pulmonary artery lesions of chronic thromboembolic pulmonary hypertension. (23555449)
2011
16
Recent advances in chronic thromboembolic pulmonary hypertension. (21620730)
2011
17
Chronic thromboembolic pulmonary hypertension (CTEPH): updated Recommendations of the Cologne Consensus Conference 2011. (22221974)
2011
18
Single photon emission computed tomography in chronic thromboembolic pulmonary hypertension. (20920137)
2011
19
Clinical and haemodynamic evaluation of chronic thromboembolic pulmonary hypertension patients scheduled for pulmonary thromboendarterectomy: Is schistosomiasis hypertension an important confounding factor? (21243290)
2010
20
Clinical features and management of chronic thromboembolic pulmonary hypertension in Thai. (20364561)
2010
21
Bosentan for chronic thromboembolic pulmonary hypertension: findings from a systematic review and meta-analysis. (20172593)
2010
22
Long-term outcome after pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension: a single institution experience. (19272789)
2009
23
HLA-DPB1 and NFKBIL1 may confer the susceptibility to chronic thromboembolic pulmonary hypertension in the absence of deep vein thrombosis. (19165231)
2009
24
Role for staphylococci in misguided thrombus resolution of chronic thromboembolic pulmonary hypertension. (18239156)
2008
25
Thromboendarterectomy for severe chronic thromboembolic pulmonary hypertension. (17540993)
2007
26
Role of NT-proBNP and 6MWD in chronic thromboembolic pulmonary hypertension. (17706409)
2007
27
Long-term bosentan in chronic thromboembolic pulmonary hypertension. (16699254)
2007
28
Chronic thromboembolic pulmonary hypertension - assessment by magnetic resonance imaging. (16838142)
2007
29
Six-minute walk distance as parameter of functional outcome after pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension. (17258590)
2007
30
Effects of pulmonary thromboendarterectomy on right-sided echocardiographic parameters in patients with chronic thromboembolic pulmonary hypertension. (16770978)
2006
31
Assessment of operability in chronic thromboembolic pulmonary hypertension. (16963538)
2006
32
Angiotensin-converting enzyme gene polymorphisms and prognosis in chronic thromboembolic pulmonary hypertension. (16936432)
2006
33
Pulmonary artery-to-pulmonary artery anastomoses: angiographic demonstration in patients with chronic thromboembolic pulmonary hypertension. (16488207)
2006
34
Long-term recovery of exercise ability after pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension. (16996930)
2006
35
The efficacy of bosentan in inoperable chronic thromboembolic pulmonary hypertension: a 1-year follow-up study. (16611652)
2006
36
Bosentan in inoperable chronic thromboembolic pulmonary hypertension. (16061720)
2005
37
Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension. (15735803)
2005
38
Chronic thromboembolic pulmonary hypertension. (15302364)
2004
39
High prevalence of elevated clotting factor VIII in chronic thromboembolic pulmonary hypertension. (12958604)
2003
40
Thrombophilic factors in chronic thromboembolic pulmonary hypertension. (11555695)
2001
41
Chronic thromboembolic pulmonary hypertension. (11590849)
2001
42
Plasma monocyte chemoattractant protein-1 and pulmonary vascular resistance in chronic thromboembolic pulmonary hypertension. (11463608)
2001
43
Three-dimensional visualization of pulmonary thromboemboli in chronic thromboembolic pulmonary hypertension with multiple detector-row spiral computed tomography. (11413092)
2001
44
Surgical treatment of chronic thromboembolic pulmonary hypertension. (10700671)
2000
45
Chronic Thromboembolic Pulmonary Hypertension. (11096519)
2000
46
Surgical treatment for chronic thromboembolic pulmonary hypertension under profound hypothermia and circulatory arrest in 24 patients. (10875595)
1999
47
A successful case of pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension with a thrombus in the right ventricle. (10333425)
1999
48
Lupus anticoagulant, heparin use, and thrombocytopenia in patients with chronic thromboembolic pulmonary hypertension: a preliminary report. (7573095)
1995
49
Acute pulmonary embolism and chronic thromboembolic pulmonary hypertension: is there a relationship? (2044728)
1991
50
Chronic thromboembolic pulmonary hypertension following ventriculo-atrial shunting. (282858)
1978

Variations for Chronic Thromboembolic Pulmonary Hypertension

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Expression for genes affiliated with Chronic Thromboembolic Pulmonary Hypertension

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Search GEO for disease gene expression data for Chronic Thromboembolic Pulmonary Hypertension.

Pathways for genes affiliated with Chronic Thromboembolic Pulmonary Hypertension

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Compounds for genes affiliated with Chronic Thromboembolic Pulmonary Hypertension

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Compounds related to Chronic Thromboembolic Pulmonary Hypertension according to GeneCards Suite gene sharing:

(show all 20)
idCompoundScoreTop Affiliating Genes
1batroxobin439.7FGB, FGA
2sucralfate43 1210.7FGB, FGA
3rsai439.7FGB, FGA
4hirudin439.6FGB, FGA
5ptca439.5NPPB, FGA
6thallium439.5NPPB, FABP3
7mibg439.4NPPB, FABP3
8dipyridamole43 59 28 1212.4FGA, NPPB
9p00001439.4NPPB, FABP3
10aprotinin43 1210.3FGA, NPPB
11aspirin43 49 28 2412.2FGA, NPPB
12p003439.1NPPB, FABP3
13p002439.0FABP3, NPPB
14norepinephrine43 24 1210.9FABP3, NPPB, FGA
15prostacyclin438.9FGA, NPPB
16lactate438.9FABP3, NPPB, FGA
17nacl438.9NPPB, FGA, FGB
18creatinine438.9FABP3, NPPB, FGA
19heparin43 28 24 1211.7FGB, FGA, NPPB
20tyrosine438.2FABP3, NPPB, FGA, FGB

GO Terms for genes affiliated with Chronic Thromboembolic Pulmonary Hypertension

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Cellular components related to Chronic Thromboembolic Pulmonary Hypertension according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1fibrinogen complexGO:00055779.5FGB, FGA
2platelet alpha granuleGO:00310919.5FGA, FGB
3platelet alpha granule lumenGO:00310939.5FGA, FGB
4cell cortexGO:00059389.4FGB, FGA
5external side of plasma membraneGO:00098979.4FGA, FGB
6blood microparticleGO:00725629.3FGB, FGA
7extracellular spaceGO:00056158.3NPPB, FGA, FGB

Biological processes related to Chronic Thromboembolic Pulmonary Hypertension according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein polymerizationGO:00512589.4FGB, FGA
2platelet activationGO:00301689.4FGB, FGA
3response to calcium ionGO:00515929.3FGB, FGA
4platelet degranulationGO:00025769.1FGB, FGA

Molecular functions related to Chronic Thromboembolic Pulmonary Hypertension according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein binding, bridgingGO:00306749.4FGB, FGA
2receptor bindingGO:00051028.3FGB, FGA, NPPB

Products for genes affiliated with Chronic Thromboembolic Pulmonary Hypertension

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  • Antibodies
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Sources for Chronic Thromboembolic Pulmonary Hypertension

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet