MCID: CHR415
MIFTS: 37

Chronic Venous Leg Ulcers malady

Aliases & Classifications for Chronic Venous Leg Ulcers

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Aliases & Descriptions for Chronic Venous Leg Ulcers:

Name: Chronic Venous Leg Ulcers 35 50

Summaries for Chronic Venous Leg Ulcers

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MalaCards based summary: Chronic Venous Leg Ulcers is related to autoimmune polyendocrine syndrome type 1 and chondrodysplasia punctata, rhizomelic, type 1. An important gene associated with Chronic Venous Leg Ulcers is TIMP1 (TIMP Metallopeptidase Inhibitor 1), and among its related pathways are Cell adhesion_ECM remodeling and Angiogenesis (CST). Affiliated tissues include skin, neutrophil and testes, and related mouse phenotypes are Decreased Salmonella-containing vacuole maturation and respiratory system.

Related Diseases for Chronic Venous Leg Ulcers

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Diseases related to Chronic Venous Leg Ulcers via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)
idRelated DiseaseScoreTop Affiliating Genes
1autoimmune polyendocrine syndrome type 110.2MMP9, TIMP1
2chondrodysplasia punctata, rhizomelic, type 110.2MMP9, TIMP1
3appendix carcinoid tumor10.2MMP9, TIMP1
4schwannomatosis10.1MMP9, TIMP1
5striated muscle rhabdoid tumor10.1MMP9, TIMP1
6maxillary neoplasm10.1MMP9, TIMP1
7adenoid squamous cell carcinoma10.1MMP9, TIMP1
8retinal drusen10.1MMP9, TIMP1
9nodular cutaneous amyloidosis10.1MMP9, TIMP1
10penis agenesis10.1ITGA4, MMP9
11chordoid meningioma10.1MMP9, TIMP1
12perrault syndrome10.1ITGA4, TIMP1
13breast abscess10.1MMP9, TIMP1
14kernicterus due to isoimmunization10.1ITGA4, LTA
15renal oncocytoma10.1MMP9, TIMP1
16burns10.1MMP9, TIMP1
17polyneuropathy in collagen vascular disease10.1FASLG, MMP9
18optic nerve neoplasm10.0MMP9, TIMP1
19lysosomal storage disease10.0MYC, TIMP1
20mixed ductal-endocrine carcinoma10.0MMP9, TIMP1
21neonatal jaundice10.0MMP9, TIMP1
22breast adenomyoepithelioma9.9FASLG, MMP9, TIMP1
23aortic aneurysm, familial thoracic 69.9FASLG, MMP9, TIMP1
24advanced sleep phase syndrome, familial, 19.9ITGA4, LTA, MMP9
25central nervous system teratoma9.9MMP9, TIMP1
26chronic venous insufficiency9.9
27venous insufficiency9.9
28thrombophilia9.9
29breast papillary carcinoma9.9MMP9, MYC, TIMP1
30progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 39.8MMP9, MYC, TIMP1
31pituitary carcinoma9.8FASLG, MYC
32hemochromatosis9.7
33reflex sympathetic dystrophy9.7
34squamous cell carcinoma9.7
35post-thrombotic syndrome9.7
36dermatitis9.7
37atopic dermatitis9.7
38nail disorder, nonsyndromic congenital, 3,9.7FASLG, MMP9, MYC
39congenital hypomyelination neuropathy9.2FASLG, ITGA4, LTA, MMP9, MYC, TIMP1

Graphical network of the top 20 diseases related to Chronic Venous Leg Ulcers:



Diseases related to chronic venous leg ulcers

Symptoms & Phenotypes for Chronic Venous Leg Ulcers

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GenomeRNAi Phenotypes related to Chronic Venous Leg Ulcers according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00133-A-210.0ITGA4, MYC

MGI Mouse Phenotypes related to Chronic Venous Leg Ulcers according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053889.2FASLG, LTA, MMP9, TIMP1
2MP:00053719.1LTA, MMP9, MYC, TIMP1
3MP:00020068.9FASLG, MMP9, MYC, TIMP1
4MP:00053858.0FASLG, ITGA4, LTA, MMP9, MYC, TIMP1
5MP:00053978.0FASLG, ITGA4, LTA, MMP9, MYC, TIMP1
6MP:00053877.9FASLG, ITGA4, LTA, MMP9, MYC, TIMP1
7MP:00107687.9FASLG, ITGA4, LTA, MMP9, MYC, TIMP1
8MP:00053907.6FASLG, LTA, MMP9, MYC, TIMP1

Drugs & Therapeutics for Chronic Venous Leg Ulcers

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Drugs for Chronic Venous Leg Ulcers (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 164)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
PetrolatumapprovedPhase 4938009-03-8
Synonyms:
Multi-hydrocarbon
Paraffinum album
Paraffinum flavum
Petrolatum base
Petrolatum, white
 
Petrolatum,amber
Petrolatum,white
Petroleum jelly
Soft paraffin
White petrolatum
White, soft paraffin
Yellow soft paraffin
2
Coal tarapprovedPhase 42028007-45-2
Synonyms:
 
Coal tars
Tar, coal
3Anti-Infective AgentsPhase 4, Phase 3, Phase 2, Phase 122062
4
BismuthPhase 4, Phase 11407440-69-916682734, 105143
Synonyms:
17034_FLUKA
24267-48-9
25243-76-9
264008_ALDRICH
265462_ALDRICH
265470_ALDRICH
452386_ALDRICH
556130_ALDRICH
7440-69-9
83Bi
95372_ALDRICH
95372_FLUKA
95375_FLUKA
AC1NSDYX
AC1O4PN8
AR-1I0647
BISMUTH, 99.95%
 
BISMUTH, 99.999%
Bi
Bismut
Bismuth standard for AAS
Bismuth standard for ICP
Bismuth(III) nitrate solution
Bismuth, elemental
Bismuth-209
C15471
CHEBI:33301
CID5359367
EINECS 231-177-4
HSDB 2078
LS-44708
LTBB002773
MolPort-003-925-759
Wismut
bismuth
bismuto
5MitogensPhase 4, Phase 3, Phase 1, Phase 21617
6Carboxymethylcellulose SodiumPhase 4, Phase 3185
7HemostaticsPhase 4, Phase 31443
8CatharticsPhase 4, Phase 3537
9Gastrointestinal AgentsPhase 4, Phase 3, Phase 18402
10LaxativesPhase 4, Phase 3537
11CoagulantsPhase 4, Phase 31500
12AminaftonePhase 41
13
Nitric OxideapprovedPhase 3, Phase 161710102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
14
Isosorbide DinitrateapprovedPhase 35987-33-26883
Synonyms:
1,4:3, 6-Dianhydro-D-glucitol dinitrate
1,4:3,6-Dianhydro-D-glucitol dinitrate
1,4:3,6-Dianhydrosorbitol 2, 5-dinitrate
1,4:3,6-Dianhydrosorbitol 2,5-dinitrate
1,4:3,6-dianhydro-2,5-di-O-nitro-D-glucitol
54650-95-2
59812_ALDRICH
59812_FLUKA
6659-58-1
87-33-2
AB00513900
AC-12153
AC1L1NIG
Angidil
Astridine
BPBio1_001021
BSPBio_000927
BSPBio_002080
BiDil
C07456
C6H8N2O8
CCRIS 1910
CHEBI:6061
CID6883
Cardio 10
Cardis
Cardonit 40
Carvanil
Carvasin
Cedocard
Cedocard Retard
Cedocard retard
Claodical
Cornilat
Coronex
Corosorbide
Corovliss
D-Glucitol, 1,4:3,6-dianhydro-, 2,5-dinitrate
D-Glucitol, 1,4:3,6-dianhydro-, dinitrate
D-Isosorbide dinitrate
D-Isosorbide dinitrate-Lactose mixture
D00516
D007548
DB00883
Dianhydrosorbitol 2,5-dinitrate
Difutrat
Dignionitrat
Dilatrate
Dilatrate SR
Dilatrate-SR
Dilatrate-sr (TN)
Diniket
Dinitrate d'isosorbide
Dinitrate d'isosorbide [INN-French]
Dinitrate, Isosorbide
Dinitrato de isosorbida
Dinitrato de isosorbida [INN-Spanish]
Dinitroisosorbide
Dinitrosorbide
Disorlon
DivK1c_000436
EINECS 201-740-9
Emoper
EureCor
Flindix
Frandol
Glucitol, 1,4:3, 6-dianhydro-, dinitrate,
HMS1570O09
HMS1920H15
HMS2091P05
HMS501F18
HSDB 3417
Harrical
IBD 20
IDI1_000436
ISD
ISDN
ISOSORBIDE DINITRATE
Ismotic
Iso Bid
Iso-Bid
Iso-Mack
Iso-Puren
IsoBid
Isochron
Isodinit
Isoket
Isoket Retard 120
Isoket Retard-120
Isoket Retard120
 
Isoket retard 40
Isomak R
Isorbid
Isordil
Isordil (TN)
Isordil Tembids
Isosorbide 2,5-dinitrate
Isosorbide dinitrate
Isosorbide dinitrate (JP15/USP/INN)
Isosorbide dinitrate [USAN:INN:BAN:JAN]
Isosorbide dinitrate mixture with not <60% lactose, mannose, starch or calcium hydrogen phosphate [UN2907] [Flammable solid]
Isosorbide dinitrate mixture with not <60% lactose, mannose, starch or calcium hydrogen phosphate [UN2907] [Flammable solid]
Isosorbide dinitrato
Isosorbide dinitrato [DCIT]
Isosorbidi dinitras
Isosorbidi dinitras [INN-Latin]
Isosorbidi nitras
Isostat
Isotrate
KBio1_000436
KBio2_000643
KBio2_003211
KBio2_005779
KBio3_001580
KBioGR_000429
KBioSS_000643
Korodil
LS-71376
Langoran
Laserdil
Lomilan
MLS001333561
MLS001333562
Maycor
MolPort-003-666-213
Myorexon
NCGC00178830-01
NCGC00178830-02
NINDS_000436
NSC 80038
NSC80038
Nitrosorbid
Nitrosorbide
Nitrosorbon
Nosim
Prestwick0_000714
Prestwick1_000714
Prestwick2_000714
Prestwick3_000714
Prestwick_81
Resoidan
Rifloc Retard
Rigedal
SDM No. 40
SDM No. 50
SMR000857256
SPBio_001058
SPBio_002848
SPECTRUM1500358
SST-101
Sorate-10
Sorate-5
Sorbangil
Sorbide
Sorbide T.D.
Sorbide nitrate
Sorbide, dinitrate
Sorbidi nitras
Sorbidilat
Sorbidinitrate
Sorbidnitrate
Sorbislo
Sorbitrate
Sorbonit
Sorquad
Sorquat
Spectrum2_001069
Spectrum3_000600
Spectrum4_000025
Spectrum5_001057
Spectrum_000163
TYB 3215
Tinidil
Titradose
UN2907
UNII-IA7306519N
Vascardin
Vasodilat
Vasorbate
Xanyl
ZINC18089317
[(3S,3aS,6R,6aS)-3-nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate
15
SorbitolapprovedPhase 33450-70-45780
Synonyms:
(-)-Sorbitol
(−)-sorbitol
D-(−)-sorbitol
D-Glucitol
D-Sorbit
D-Sorbitol
D-Sorbol
D-glucitol
Diakarmon
Esasorb
Foodol D 70
G-ol
Glucarine
Glucitol
Karion
Karion instant
Kyowa Powder 50M
L-Gulitol
Multitol
Neosorb
Neosorb 20/60DC
Neosorb 70/02
Neosorb 70/70
Neosorb P 20/60
Neosorb P 60
Neosorb P 60W
Nivitin
Resulax
Sionit
Sionit K
Sionite
 
Sionon
Siosan
Sorbex M
Sorbex R
Sorbex Rp
Sorbex S
Sorbex X
Sorbilande
Sorbilax
Sorbit
Sorbit D 70
Sorbit D-Powder
Sorbit DP
Sorbit DP 50
Sorbit Kyowa Powder 50M
Sorbit L 70
Sorbit S
Sorbit T 70
Sorbit W 70
Sorbit W-Powder
Sorbit W-Powder 50
Sorbit WP
Sorbite
Sorbitol F
Sorbitol FK
Sorbitol FP
Sorbitol S
Sorbitol syrup C
Sorbitur
Sorbo
Sorbogem 712
Sorbol
Sorbostyl
16
IbuprofenapprovedPhase 351815687-27-13672
Synonyms:
(4-isobutylphenyl)-α-methylacetic acid
(RS)-ibuprofen
(±)-2-(p-isobutylphenyl)propionic acid
(±)-ibuprofen
(±)-p-isobutylhydratropic acid
(±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid
139466-08-3
15687-27-1
2-(4-isobutylphenyl)propanoic acid
4-isobutylhydratropic acid
58560-75-1
AC-11312
AC1L1GGE
AC1Q1P84
AC1Q1P85
ACHES-N-PAIN
ARONIS23835
Act-3
Actiprofen
Adex 200
Adran
Advil
Advil (TN)
Advil Liqui-Gels
Ak+C2278tren
Alaxan
Algofen
Am-Fam 400
Amelior
Amersol
Amibufen
Anafen
Anco
Andran
Anflagen
Antagil
Antalfene
Antarene
Antiflam
Apo-Ibuprofen
Apsifen
Apsifen-F
Artofen
Artril
Artril 300
BB_SC-1358
BIDD:GT0050
BRN 2049713
Balkaprofen
Betaprofen
Bloom
Bluton
Brofen
Brufanic
Brufen
Brufen 400
Bruflam
Brufort
Buburone
Bufeno
Bufigen
Bukrefen
Bupron
Buracaps
Burana
Butylenin
C01588
C13H18O2
CCRIS 3223
CHEBI:5855
CHEMBL521
CID3672
CPD000058184
Cap-Profen
Carol
Cesra
Children's Advil
Children's Elixsure
Children's Ibuprofen
Children's Motrin
Citalgan
Cobo
Codral
Combiflam
Cunil
D00126
D007052
DB01050
DOLO PUREN
Daiprophen
Dalsy
Dansida
Deep Relief
Dentigoa
Dibufen
Dignoflex
Dolgin
Dolgirid
Dolgit
Dolibu
Dolmaral
Dolo-Dolgit
Dolocyl
Dolofen
Dolofen-F
Dolofin
Dolofort
Dologel
Dolomax
Doloren
Dolormin
Doltibil
Dolven
Donjust B
Dorival
Drin
Duafen
Duobrus
Dura-Ibu
Duralbuprofen
Dysdolen
EU-0100691
Easifon
Ebufac
Emflam
Emflam-200
Emodin
Epobron
Eputex
Ergix
Esprenit
Exneural
Faspic
Femadon
Femafen
Femapirin
Femidol
Fenbid
Fenbid Spansule
Fendol
Fenspan
Fibraflex
Gelufene
Gofen
Grefen
Gynofug
HMS1920F15
HMS2089P05
HMS2091N03
HMS502M09
HSDB 3099
Haltran
I 4883
I01-7039
I0415
I4883_SIGMA
I7905_SIAL
IB-100
IDI1_000887
IP 82
IP-82
IP82
Ibol
Ibren
Ibu
Ibu-Attritin
Ibu-Slo
Ibu-Tab
Ibu-Tab 200
Ibu-slo
Ibu-slow
Ibubest
Ibubeta
Ibucasen
Ibudol
Ibudolor
 
Ibufen
Ibuflamar
Ibufug
Ibugel
Ibugen
Ibugesic
Ibuhexal
Ibulagic
Ibular
Ibulav
Ibuleve
Ibulgan
Ibumed
Ibumerck
Ibumetin
Ibupirac
Ibuprin
Ibuprocin
Ibuprofene
Ibuprofeno
Ibuprofenum
Ibuprohm
Ibuprophen
Ibusal
Ibutid
Ifen
Inabrin
Inflam
Inoven
Ipren
Irfen
Isodol
Jenaprofen
Junifen
Junior Strength Advil
Junior Strength Ibuprofen
Junior Strength Motrin
KBio1_000887
KBio2_001329
KBio2_003897
KBio2_006465
KBio3_001390
Kesan
Kratalgin
LS-7454
Lamidon
Lebrufen
Librofem
Lidifen
Liptan
Lopane
MLS000069733
MLS001146965
Malafene
Manypren
Medipren
Melfen
Mensoton
Midol
Midol 200
Moment
Motrin
Motrin (TN)
Motrin IB
Mynosedin
NCI60_002065
NINDS_000887
NSC 256857
NSC256857
Nagifen-D
Napacetin
Narfen
Neo-Helvagit
Neo-Mindol
NeoProfen
Neobrufen
Nerofen
Noalgil
Nobafon
Nobfelon
Nobfen
Nobgen
Noritis
Norton
Novadol
Novo-Profen
Novogent
Novogent N
Novoprofen
Nuprilan
Nuprin
Nurofen
Optifen
Opturem
Oralfene
Ostarin
Ostofen
Ozonol
P-Isobutylhydratropic Acid
Paduden
Panafen
Pantrop
Para-Isobutylhydratropic Acid
Paxofen
Pedia-Profen
PediaProfen
Pediaprofen
Pediatric Advil
Perofen
Proartinal
Profen
Proflex
Provon
Quadrax
R.D. 13621
RD 13621
Rafen
Ranofen
Rebugen
Relcofen
Rhinadvil
Rofen
Roidenin
Rufen
Rufin
Rupan
SAM002264619
SMR000058184
SPBio_000178
STK177358
Sadefen
Salivia
Salprofen
Seclodin
Sednafen
Seklodin
Seskafen
Siyafen
Solpaflex
Solufen
Stelar
Sugafen
Suprafen
Suspren
Syntofene
TL8001184
Tab-Profen
Tabalon
Tabalon 400
Tatanal
Tempil
Tofen
Togal N
Tonal
Trendar
U 18573
U-18,573
U-18573
UCB 79171
Unipron
Upfen
Uprofen
Urem
VUFB 9649
Zafen
Zofen
alpha-(4-Isobutylphenyl)propionate
alpha-(4-Isobutylphenyl)propionic acid
alpha-p-Isobutylphenylpropionate
alpha-p-Isobutylphenylpropionic acid
ibuprofen
p-Isobutyl-2-phenylpropionate
p-Isobutyl-2-phenylpropionic acid
p-Isobutylhydratropate
p-Isobutylhydratropic acid
α-(4-isobutylphenyl)propionic acid
α-(p-isobutylphenyl)propionic acid
17
Glucosamineapproved, NutraceuticalPhase 3, Early Phase 11913416-24-8439213
Synonyms:
(+)-2-amino-2-deoxy-D-glucopyranose
(2R,3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol
(2S,5R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol
(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol
14257-69-3
2-Amino-2-deoxy-D-Glucose
2-Amino-2-deoxy-D-glucopyranose
2-Amino-2-deoxy-D-glucose
2-Amino-2-deoxy-beta-D-glucopyranose
2-Amino-2-deoxyglucose
2-Aminoglucose
2-Deoxy-2-amino-D-glucose
2-Deoxy-2-aminoglucose
2-amino-2-deoxy-D-glucopyranose
2-amino-2-deoxyglucose
2351-15-7
28905-10-4
2B4D44B2-D5AC-4DA4-9BE6-A4AE9574E4A6
3416-24-8
4-04-00-02017 (Beilstein Handbook Reference)
58-87-7
58267-75-7
6490-70-6
880765-44-6
90-77-7
911653-84-4
AC1L2D1C
AC1L96WB
AC1L9B8P
AC1Q4UBH
BRN 1724602
BSPBio_002086
C00329
C08349
CHEBI:28393
CHEBI:47977
CHEMBL234432
CID18897
CID439213
CID441477
CPD0-1193
Chitosamine
Cosamin
D-(+)-Glucosamine
 
D-Glucosamine
D-glucosamine
D04334
DB01296
DivK1c_000261
EINECS 222-311-2
GCS
Glucosamina
Glucosamina [INN-Spanish]
Glucosamine (USAN/INN)
Glucosamine [USAN:INN]
Glucosaminum
Glucosaminum [INN-Latin]
HMS500N03
HSDB 7469
IDI1_000261
InChI=1/C6H13NO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1,7H2/t2-,3-,4-,5-,6-/m1/s1
KBio1_000261
KBio2_001311
KBio2_003879
KBio2_006447
KBio3_001306
KBioGR_000970
KBioSS_001311
LS-71671
MolPort-002-507-091
MolPort-003-944-937
NCGC00164421-01
NCGC00178826-01
NINDS_000261
SPBio_000477
STK801823
Spectrum2_000519
Spectrum3_000443
Spectrum4_000565
Spectrum5_000756
Spectrum_000831
Viartril-S
beta-D-Glucosamine
bmse000247
chitosamine
glucosamine
nchembio.189-comp4
nchembio.2007.41-comp7
nchembio.412-comp5
partially N-deacetylated poly-beta-1,6-N-acetyl-D-glucosamine
18Pharmaceutical SolutionsPhase 3, Phase 2, Phase 18192
19Calcium, DietaryPhase 3, Phase 1, Phase 25713
20Vasodilator AgentsPhase 3, Phase 13543
21Bone Density Conservation AgentsPhase 3, Phase 23376
22Angiogenesis Modulating AgentsPhase 3, Phase 14185
23Platelet-derived growth factor BBPhase 3, Phase 128
24Chelating AgentsPhase 31423
25Nitric Oxide DonorsPhase 3, Phase 1114
26Angiogenesis Inducing AgentsPhase 3, Phase 140
27Anticholesteremic AgentsPhase 32025
28IsosorbidePhase 359
29Hypolipidemic AgentsPhase 32785
30diureticsPhase 31418
31AntimetabolitesPhase 312054
32isosorbide-5-mononitratePhase 359
33Natriuretic AgentsPhase 31697
34Lipid Regulating AgentsPhase 32766
35
protease inhibitorsPhase 3, Phase 15471
Synonyms:
 
protease inhibitors
36ThrombinPhase 3304
37HIV Protease InhibitorsPhase 3, Phase 15470
38Anti-HIV AgentsPhase 33162
39Antiviral AgentsPhase 39967
40Anti-Retroviral AgentsPhase 33296
41Calcium DobesilatePhase 38
42CitrateNutraceuticalPhase 3, Phase 1, Phase 21160
43
ChitosanNutraceuticalPhase 3479012-76-471853
Synonyms:
CTA 4
Chicol
Chitopearl 3510
Chitopearl BC 3000
Chitopearl BCW 2500
Chitopearl BCW 3000
Chitopearl BCW 3500
Chitopearl BCW 3505
Chitopearl BCW 3507
Deacetylchitin
Flonac C
Flonac N
 
Kimitsu Chitosan F
Kimitsu Chitosan F 2
Kimitsu Chitosan H
Kimitsu Chitosan L
Kimitsu Chitosan M
Kytex H
Kytex M
Poliglusam
Sea Cure F
Sea Cure Plus
YEA
beta-1,4-Poly-D-glucosamine
beta-1,4-Poly-delta-glucosamine
44
Citric Acidnutraceutical, vet_approvedPhase 3, Phase 1, Phase 2116077-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
45
Aspirinapproved, vet_approvedPhase 2115250-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalicylsäure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide acetylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Aloxiprimum
Asacard
Asagran
Asatard
Ascoden-30
Aspalon
Aspec
Aspergum
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin [BAN:JAN]
Aspirina 03
Aspirine
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Aspirin 8 Hour
Bayer Buffered
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Plus
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Bufferin
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Cemirit
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ecolen
Ecotrin
Empirin
Empirin with Codeine
Endosprin
Endydol
Entericin
Enterophen
 
Enterosarein
Enterosarine
Entrophen
Extren
Globentyl
Globoid
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Helicon
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Levius
Lopac-A-5376
Lopac0_000038
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medisyl
Micristin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Persistin
Pharmacin
Pirseal
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
Supac
Tasprin
Temperal
Toldex
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
acide 2-(acétyloxy)benzoïque
acide acétylsalicylique
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
salicylic acid acetate
ácido acetilsalicílico
46
TimololapprovedPhase 225226839-75-833624, 5478
Synonyms:
(-)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole
(2S)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(2S)-1-[(1,1-dimethylethyl)amino]-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(S)-1-(1,1-(Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
(S)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol
(S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(S)-timolol
131628-37-0
194288-09-0
26839-75-8
26921-17-5 (maleate (1:1) salt)
AB00513729
AC1L1PYN
AC1Q59QM
Apo-Timol
Apo-Timop
Aquanil
BIDD:GT0073
BPBio1_001008
BRD-K08806317-050-03-6
BSPBio_000916
Betim
Betimol
Betimol (TN)
Blocadren
C07141
C13H24N4O3S
CAS-26921-17-5
CHEBI:9599
CHEMBL499
CID33624
CPD001456519
D08600
DB00373
DB08625
EINECS 248-032-6
HMS2089I11
HSDB 6533
Istalol
L-714,465
LS-122231
Lopac-T-6394
Lopac0_001189
MK-950
NCGC00016038-01
 
NCGC00016038-02
NCGC00016798-01
NCGC00016798-07
NCGC00022033-02
NCGC00022033-04
NCGC00022033-05
Novo-Timol
Nu-Timolol
Oprea1_640981
Optimol
Phoxal-timolol
Prestwick0_000948
Prestwick1_000948
Prestwick2_000948
Prestwick3_000948
Proflax
S(-)-Timolol maleate
S-(-)-3-(3-tert-Butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole
SAM002564238
SPBio_003075
ST072193
TIM
Temserin
Tenopt
Tim-AK
Timacar
Timacor
Timolol
Timolol (INN)
Timolol (TN)
Timolol GFS
Timolol Maleate, (1:1) Salt
Timolol [USAN]
Timolol anhydrous
Timolol maleate
Timololo
Timololum
Timololum [INN-Latin]
Timopic
Timoptic
Timoptic OcuDose
Timoptic in Ocudose
Timoptic-XE
Timoptol
Tocris-0649
UNII-817W3C6175
timolol
47
Methyl salicylateapproved, vet_approvedPhase 212119-36-84133
Synonyms:
2-(Methoxycarbonyl)phenol
2-Carbomethoxyphenol
2-Hydroxybenzoic acid methyl ester
AI3-00090
Benzoic acid, 2-hydroxy-, methyl ester
FEMA 2745
 
Methyl 2-hydroxybenzoate
Methyl O-hydroxybenzoate
Methyl ester 2-hydroxy-benzoic acid
Methyl o-hydroxybenzoate
Methyl salicylate, 8CI
Methylester kyseliny salicylove
O-Hydroxybenzoic acid, methyl ester
48
Folic Acidapproved, nutraceutical, vet_approvedPhase 2, Phase 1439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
49
Pyridoxineapproved, nutraceutical, vet_approvedPhase 218865-23-61054
Synonyms:
(5-hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphate
12001-78-4
2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine
2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridine
2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin
2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin [German]
2-Methyl-3-hydroxy-4,5-dihydroxymethylpyridine
2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine
2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl) pyridine
2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine
2-methyl-4,5-dimethylol-pyridin-3-ol
2B3E07D2-E4CC-4CC5-B085-6070BA01F9F0
3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride
3-Hydroxy-2-Picoline-4,5-dimethanol
3-Hydroxy-4,5-dihydroxymethyl-2-methylpyridine hydrochloride
3-Hydroxy-4,5-dimethylol-.alpha.-picoline hydrochloride
3-Hydroxy-4,5-dimethylol-alpha-picoline
3-Hydroxy-4,5-dimethylol-alpha-picoline hydrochloride
3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine
4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol
4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride
4,5-bis(hydroxymethyl)-2-methyl-3-pyridinol hydrochloride
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol
4,5-bis(hydroxymethyl)-2-methylpyridine-3-ol
4-Deoxypyridoxine 5'-phosphate
47862_SUPELCO
5-Hydroxy-6-methyl-3,4-pyridinedicarbinol hydrochloride
5-Hydroxy-6-methyl-3,4-pyridinedimethanol
5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride
5-Hydroxy-6-methyl-3,4-pyridinedimethanol, hydrochloride
58-56-0
58-56-0 (HCL)
58-56-0 (hydrochloride)
65-23-6
65-23-6 (Parent)
8059-24-3
85078-23-5
AC-12024
AC-14512
AC-907/25014218
AC1L1AMH
AC1L1LMI
AC1L2XK2
AC1Q22HP
AC1Q2G66
AC1Q3F63
AI3-19016
AIDS-006784
AIDS006784
AR-1A6363
AR-1J1632
Adermin hydrochloride
Adermine
Adermine hydrochloride
Aderomine hydrochloride
Aderoxin
Aderoxine
Alestrol
BB_NC-0050
BIDD:PXR0180
BPBio1_000646
BSPBio_000586
Becilan
Beesix
Benadon
Bonasanit
C00314
C8H11NO3
CAS-58-56-0
CBDivE_015627
CCRIS 1903
CHEBI:16709
CHEBI:30961
CHEMBL1200756
CHEMBL1364
CID104817
CID1054
CID6019
CPD0-1221
Campoviton 6
Cernevit-12
D02179
D025101
D08454
DB00165
EINECS 200-386-2
EINECS 200-603-0
EINECS 232-503-8
Godabion
Gravidox
HMS1569N08
HMS2093L07
HSDB 1212
Hexa-Betalin
Hexa-Betalin (R)
Hexa-betalin (TN)
Hexabetalin
Hexabione hydrochloride
 
Hexavibex
Hexermin
Hexermine
Hexobion
Hydoxin
I02-1897
I02-2297
KST-1A8556
LS-134393
LS-187072
LS-2332
MLS001074329
MLS002153915
MolPort-002-137-856
MolPort-002-319-991
MolPort-005-933-330
NCGC00016261-01
NCGC00164317-01
NCGC00180946-01
NSC 36225
NSC36225
NSC36225 (HCL)
Nestrex
Oprea1_061614
P0561
P4722_SIAL
P5669_SIGMA
P6280_SIGMA
P8666_SIGMA
P9755_SIAL
PN
PN HCl
PYRIDOXINE HYDROCHLORIDE
PYRIDOXINE HYDROCHLORIDE, U.S.P.
Paxadon
Piridossina
Piridossina [DCIT]
Piridoxina
Piridoxina [INN-Spanish]
Prestwick0_000623
Prestwick1_000623
Prestwick2_000623
Prestwick3_000623
Prestwick_925
Pydox
Pyridipca
Pyridox
Pyridoxin
Pyridoxin hydrochloride
Pyridoxine
Pyridoxine (INN)
Pyridoxine HCl
Pyridoxine Hydrochloride (B6)
Pyridoxine [INN:BAN]
Pyridoxine chloride
Pyridoxine hydrochloride (JP15/USP)
Pyridoxine hydrochloride [USAN:JAN]
Pyridoxine hydrogen chloride
Pyridoxine monohydrochloride
Pyridoxine, hydrochloride
Pyridoxine-HCl Microencapsulated
Pyridoxinium chloride
Pyridoxinum
Pyridoxinum [INN-Latin]
Pyridoxinum hydrochloricum
Pyridoxinum hydrochloricum (Hungarian)
Pyridoxol
Pyridoxol hydrochloride
Pyridoxol, hydrochloride
Pyridoxolum
Rodex
Rodex (R)
Rodex TD
SMP2_000230
SMR000674613
SPBio_002805
STK177324
STOCK1N-08684
Spondylonal
Tex Six T.R.
TimTec1_000657
UNII-68Y4CF58BV
UNII-KV2JZ1BI6Z
Vitamin B 6
Vitamin B6
Vitamin B6-hydrochloride
Vitamin V6
Vitamin V6 (TN)
Vitamin-?B6
Vitamin-?B6 hydrochloride
Vitaped
WLN: T6NJ B1 CQ D1Q E1Q &GH
ZINC00049154
ZINC21983293
bmse000288
c1302
component of Alestrol
nchembio.93-comp1
pyridoxine
vitamin B6
50
Pyridoxalapproved, nutraceuticalPhase 218766-72-81050
Synonyms:
2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine
3-Hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde
3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde
 
3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde
3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde
Piridoxal
Pyridoxal
Pyridoxaldehyde

Interventional clinical trials:

(show top 50)    (show all 139)
idNameStatusNCT IDPhase
1Clinical Evaluation of the SNaP Wound Care SystemUnknown statusNCT01113658Phase 4
2AQUACEL® Ag Dressing and Urgotul® Silver Dressing on Healing of Chronic Venous Leg UlcersCompletedNCT01084577Phase 4
3DermACELL in Subjects With Chronic Wounds of the Lower ExtremitiesCompletedNCT01970163Phase 4
4Neuromuscular Electrical Therapy in Venous UlcersCompletedNCT01372020Phase 4
5A Pilot Trial of the Use of ReCell® Autologous Cell Harvesting Device for Venous Leg UlcersCompletedNCT01743053Phase 4
6Iliac Vein Stenting in Advanced Chronic Venous InsufficiencyCompletedNCT02149212Phase 4
7Effectiveness of Aurix Therapy in Venous Leg UlcersRecruitingNCT02352454Phase 4
8ACTICOAT™ for the Treatment of Burns and Chronic WoundsNot yet recruitingNCT02852148Phase 4
9TruSkin®: Study for Treatment of Chronic Venous Leg UlcersTerminatedNCT02936128Phase 4
10Effectiveness of Aurix Therapy in Venous Leg UlcersWithdrawnNCT02940587Phase 4
11A Post-Marketing Clinical Study of Apligraf for Venous Leg UlcersWithdrawnNCT00648674Phase 4
12A Comparison of OASIS Wound Matrix With Approved Dressings for Skin Graft Donor SitesWithdrawnNCT02994589Phase 4
13Chronic Venous ULcer TReatment Analyzing Bio-Electrical Stimulation TherapyUnknown statusNCT00678847Phase 2, Phase 3
14Biatain Ibu vs. Biatain in Painful Chronic Venous Leg UlcersCompletedNCT00627094Phase 3
15THERMES ET VEINES: Spa for Prevention of Leg UlcersCompletedNCT00838500Phase 3
16Study to Evaluate the Performance of AQUACEL® Extra™ in Venous Leg UlcersCompletedNCT01591434Phase 3
17Pivotal Trial of Dermagraft(R) to Treat Venous Leg UlcersCompletedNCT00909870Phase 3
18Open Multi-centre Investigation to Evaluate Signs and Symptoms of Local Inflammation/Infection on Chronic Ulcers and Partial Thickness Burns When Using Mepilex Border Ag as an Anti-microbial Wound DressingCompletedNCT01214811Phase 3
19Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot UlcersCompletedNCT02789033Phase 3
20Safety And Efficacy Of Topical Platelet Rich Plasma And Thrombin CoagulumRecruitingNCT02802995Phase 3
21Evaluation of CureXcell® in Treating Chronic Venous Leg UlcersActive, not recruitingNCT02130310Phase 3
22PRP ULCERAS: Clinical Trial Phase IIIActive, not recruitingNCT02213952Phase 3
23Clinical Trial of ECLIPSE PRP™ Wound Biomatrix in Chronic Non-Healing Venous Leg UlcersNot yet recruitingNCT02312518Phase 2, Phase 3
24Study of Combined Topical Growth Factor and Protease Inhibitor in Chronic Wound HealingNot yet recruitingNCT02845466Phase 3
25Calcium Dobesilate for Chronic Venous WoundsSuspendedNCT00979836Phase 3
26Safety and Efficacy Trial of HP802-247 in the Treatment of Chronic Venous Leg UlcersTerminatedNCT01853384Phase 3
27Clinical Effectiveness of Topical Autologous Platelet Gel for the Treatment of Venous UlcersWithdrawnNCT00273234Phase 3
28A Prospective Randomized, Double-Blind, Placebo-Controlled Trial Comparing VitroGro® ECM to Placebo in Patients With Venous Leg UlcersWithdrawnNCT01982318Phase 2, Phase 3
29Phase I/II Dose Ranging CHRONSEAL® Study in Venous Leg UlcersUnknown statusNCT00797706Phase 1, Phase 2
30Nursing Care With Patients With Venous Leg UlcersUnknown statusNCT02224300Phase 2
31Adipose Derived Regenerative Cellular Therapy of Chronic WoundsUnknown statusNCT02092870Phase 2
32Non-Healing Ulcers Without Critical Limb IschemiaUnknown statusNCT01666093Phase 2
33Surface NeuroMuscular Electrical Stimulation in the Treatment of Chronic Venous Leg UlcersCompletedNCT01801891Phase 2
34EASH Dressing on Chronic Venous Leg UlcersCompletedNCT01497210Phase 2
35The Effect of the Cosmetic Cream NMBM on Leg Ulcers - a Pilot StudyCompletedNCT01770509Phase 1, Phase 2
36Assessment of the Safety and Efficacy of DERMASTREAM™ - ENZYSTREAM™ System for the Treatment of Chronic Venous UlcersCompletedNCT00485329Phase 1, Phase 2
37Clinical Trial to Investigate Treatment With Photodynamic Therapy to Reduce Levels of Bacteria in Leg UlcersCompletedNCT00825760Phase 2
38Feasibility and Safety and Evaluation of the Potential Efficacy of Autologous Platelet-rich Plasma in the Treatment of Vascular Venous UlcersCompletedNCT01817218Phase 1, Phase 2
39Extracorporeal Shockwave Treatment for Chronic Soft Tissue WoundsCompletedNCT00545896Phase 2
40The Efficacy of Venavine Intensive® on the Quality of Life in Females With Chronic Venous InsufficiencyCompletedNCT02498327Phase 2
41Evaluation of Safety and Activity of Celaderm in Healing Venous Leg UlcersCompletedNCT00399308Phase 1, Phase 2
42Community RCT of the Effectiveness of Two Compression Bandaging TechnologiesCompletedNCT00202267Phase 2
43Evaluation of a Ionic Silver and Honey Preparation to Treat Chronic Wounds of the Lower LegsCompletedNCT01111695Phase 2
44A Study to Investigate the Efficacy, Safety and Tolerability of Nexagon® as a Topical Treatment for Subjects With Venous Leg UlcersCompletedNCT01199588Phase 2
45SNaP Wound Care System Versus Traditional NPWT Device for Treatment of Chronic WoundsCompletedNCT00951080Phase 2
46Safety Trial of the RedDress Wound Care System (RD1) in Management of Texas 1a or 2a Neuropathic Diabetic Foot Ulcers.CompletedNCT01396837Phase 2
47Study of VF001-DP in Patients With Chronic Venous Leg UlcersRecruitingNCT02973893Phase 2
48Clinical Trial to Investigate Efficacy and Safety of the IMP in Patients With Non Healing Wounds Originating From UlcersRecruitingNCT02742844Phase 1, Phase 2
49Efficacy of TR 987, Beta-1,3-1,6-D-glucan, in the Treatment of Chronic Venous Insufficiency UlcersRecruitingNCT03154619Phase 2
50Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer RecurrenceRecruitingNCT02626156Phase 2

Search NIH Clinical Center for Chronic Venous Leg Ulcers

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Chronic Venous Leg Ulcers cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Chronic Venous Leg Ulcers:
Apligraf
Embryonic/Adult Cultured Cells Related to Chronic Venous Leg Ulcers:
Bilayered bioengineered skin substitute (Apligraf, PMIDs: 12055943, 12463767, 20849380, 18615798

Genetic Tests for Chronic Venous Leg Ulcers

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Anatomical Context for Chronic Venous Leg Ulcers

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MalaCards organs/tissues related to Chronic Venous Leg Ulcers:

36
Skin, Neutrophil, Testes

Publications for Chronic Venous Leg Ulcers

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Articles related to Chronic Venous Leg Ulcers:

(show top 50)    (show all 123)
idTitleAuthorsYear
1
Phase 3 Evaluation of HP802-247 in the Treatment of Chronic Venous Leg Ulcers. (27495869)
2016
2
Estimating the Clinical Outcomes and Cost Differences Between Standard Care With and Without Cadexomer Iodine in the Management of Chronic Venous Leg Ulcers Using a Markov Model. (27356144)
2016
3
Safety and performance evaluation of a next-generation antimicrobial dressing in patients with chronic venous leg ulcers. (26095122)
2015
4
Medical grade honey in the management of chronic venous leg ulcers. (26050953)
2015
5
Healing of Recalcitrant Chronic Venous Leg Ulcers by Punch Grafts Harvested From the Scalp. (26262948)
2015
6
Randomized, controlled study of innovative spray formulation containing ozonated oil and I+-bisabolol in the topical treatment of chronic venous leg ulcers. (26280699)
2015
7
Cost analysis of negative-pressure wound therapy with instillation for wound bed preparation preceding split-thickness skin grafts for massive (>100A cm(2)) chronic venous leg ulcers. (25595397)
2015
8
Squamous cell carcinomas in chronic venous leg ulcers. Data of the German Marjolin Registry and review. (26408463)
2015
9
Nutritional profile of older adults with chronic venous leg ulcers: AA pilot study. (26141998)
2015
10
Extracellular matrix assessment of infected chronic venous leg ulcers: role of metalloproteinases and inflammatory cytokines. (24618232)
2014
11
Chronic venous leg ulcers: is topical zinc the answer? A review of the literature. (24343393)
2014
12
Chronic venous leg ulcers: is topical zinc the answer? A review of the literature. (24343392)
2014
13
Alleviation of chronic venous leg ulcers with a hand-held dielectric barrier discharge plasma generator (PlasmaDerm(Ar) VU-2010): results of a monocentric, two-armed, open, prospective, randomized and controlled trial (NCT01415622). (24666170)
2014
14
Maggots as a wound debridement agent for chronic venous leg ulcers under graduated compression bandages: a randomised controlled trial. (25300315)
2014
15
Efficacy and cost-effectiveness of octenidine wound gel in the treatment of chronic venous leg ulcers in comparison to modern wound dressings. (24589044)
2014
16
Cost-Effective Use of Silver Dressings for the Treatment of Hard-to-Heal Chronic Venous Leg Ulcers. (24945381)
2014
17
Randomized standard-of-care-controlled trial of a silica gel fibre matrix in the treatment of chronic venous leg ulcers. (24839984)
2014
18
The Effect of a Connexin43-Based Peptide on the Healing of Chronic Venous Leg Ulcers: A Multicenter, Randomized Trial. (25072595)
2014
19
Cost-effectiveness of three adjunct cellular/tissue-derived products used in the management of chronic venous leg ulcers. (25498775)
2014
20
Factors that influence healing of chronic venous leg ulcers: a retrospective cohort. (24937814)
2014
21
A topical haemoglobin spray for oxygenating chronic venous leg ulcers: a pilot study. (25382133)
2014
22
Chronic venous leg ulcers: Effects of foam sclerotherapy on healing and recurrence. (25351907)
2014
23
Comparative effectiveness of advanced wound dressings for patients with chronic venous leg ulcers: a systematic review. (24635169)
2014
24
Autologous platelet-rich plasma in treatment of chronic venous leg ulcers: A prospective case series. (25492574)
2014
25
The impact of chronic venous leg ulcers: a systematic review. (25492276)
2014
26
Healing rates following venous surgery for chronic venous leg ulcers in an independent specialist vein unit. (22833505)
2013
27
Neutrophil activity in chronic venous leg ulcers--a target for therapy? (23551462)
2013
28
Effect of foam sclerotherapy on healing and long-term recurrence in chronic venous leg ulcers. (22422794)
2013
29
Catheter-directed foam sclerotherapy for chronic venous leg ulcers. (24072751)
2013
30
Chronic venous leg ulcers are associated with high levels of metalloproteinases-9 and neutrophil gelatinase-associated lipocalin. (23531093)
2013
31
Proteolytic activity by multiple bacterial species isolated from chronic venous leg ulcers degrades matrix substrates. (23118301)
2013
32
Identification of Symptom Clusters in Patients With Chronic Venous Leg Ulcers. (23998779)
2013
33
Durability of healing from spray-applied cell therapy with human allogeneic fibroblasts and keratinocytes for the treatment of chronic venous leg ulcers: A 6-month follow-up. (23927847)
2013
34
Healing of chronic venous leg ulcers could be affected by an interaction of the hemochromatosis gene polymorphism HFE H63D with the strength of compression treatment--a re-analysis of patients from previous studies. (22150832)
2012
35
Chronic venous leg ulcers: the future of cell-based therapies. (22863327)
2012
36
Spray-applied cell therapy with human allogeneic fibroblasts and keratinocytes for the treatment of chronic venous leg ulcers: a phase 2, multicentre, double-blind, randomised, placebo-controlled trial. (22863328)
2012
37
A prospective, multi-centre, randomised, open label, parallel, comparative study to evaluate effects of AQUACELAr Ag and UrgotulAr Silver dressing on healing of chronic venous leg ulcers. (22066961)
2012
38
Exploratory study on the effectiveness of a standardized extract from Ageratina pichinchensis in patients with chronic venous leg ulcers. (22174074)
2012
39
Effectiveness and tissue compatibility of a 12-week treatment of chronic venous leg ulcers with an octenidine based antiseptic--a randomized, double-blind controlled study. (22074592)
2012
40
Skin grafting followed by low-molecular-weight heparin long-term therapy in chronic venous leg ulcers. (22018697)
2012
41
Increased Lipoprotein (a) concentrations in patients with chronic venous leg ulcers: a study on patients with or without postthrombotic syndrome. (21362083)
2011
42
Duration of wound fluid secretion from chronic venous leg ulcers is critical for interleukin-1I+, interleukin-1I^, interleukin-8 levels and fibroblast activation. (21786164)
2011
43
Insufficient and incomplete shaving in chronic venous leg ulcers leads to a poor prognosis of the skin graft: a histomorphological analysis. (21893960)
2011
44
Thrombophilia in patients with chronic venous leg ulcers-a study on patients with or without post-thrombotic syndrome. (21392126)
2011
45
Relationship between the seasonal onset of chronic venous leg ulcers and climatic factors. (21371131)
2011
46
Success rate of split-thickness skin grafting of chronic venous leg ulcers depends on the presence of Pseudomonas aeruginosa: a retrospective study. (21655269)
2011
47
Managing chronic venous leg ulcers: time for a new approach? (20216491)
2010
48
Characterization of tumor necrosis factor-I+ block haplotypes associated with susceptibility to chronic venous leg ulcers in Caucasian patients. (20854863)
2010
49
Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. (20558044)
2010
50
Managing chronic venous leg ulcers part 2: time for a new pragmatic approach? (20559185)
2010

Variations for Chronic Venous Leg Ulcers

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Expression for genes affiliated with Chronic Venous Leg Ulcers

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Search GEO for disease gene expression data for Chronic Venous Leg Ulcers.

Pathways for genes affiliated with Chronic Venous Leg Ulcers

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Pathways related to Chronic Venous Leg Ulcers according to GeneCards Suite gene sharing:

(show all 26)
idSuper pathwaysScoreTop Affiliating Genes
19.6MMP9, TIMP1
2
Show member pathways
9.6MMP9, TIMP1
39.6MMP9, TIMP1
49.6MMP9, TIMP1
59.4ITGA4, LTA
69.4ITGA4, LTA
7
Show member pathways
9.3FASLG, LTA
89.3FASLG, ITGA4
9
Show member pathways
9.2MYC, TIMP1
10
Show member pathways
9.2MMP9, MYC
119.2MMP9, MYC
129.2MMP9, MYC
13
Show member pathways
9.1ITGA4, MMP9, TIMP1
149.0FASLG, MYC
15
Show member pathways
8.8FASLG, ITGA4, LTA
168.6FASLG, MMP9, MYC
178.6FASLG, MMP9, MYC
18
Show member pathways
8.5FASLG, LTA, MYC
19
Show member pathways
8.5FASLG, LTA, MYC
208.5FASLG, ITGA4, MYC
21
Show member pathways
8.4FASLG, ITGA4, LTA, TIMP1
228.2FASLG, MMP9, MYC, TIMP1
23
Show member pathways
7.6FASLG, LTA, MMP9, MYC, TIMP1
24
Show member pathways
7.6FASLG, ITGA4, LTA, MYC, TIMP1
25
Show member pathways
7.1FASLG, ITGA4, LTA, MMP9, MYC, TIMP1
26
Show member pathways
7.1FASLG, ITGA4, LTA, MMP9, MYC, TIMP1

GO Terms for genes affiliated with Chronic Venous Leg Ulcers

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Cellular components related to Chronic Venous Leg Ulcers according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.5FASLG, LTA, MMP9, TIMP1

Biological processes related to Chronic Venous Leg Ulcers according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1extracellular matrix disassemblyGO:002261710.3MMP9, TIMP1
2endodermal cell differentiationGO:003598710.2ITGA4, MMP9
3negative regulation of fibroblast proliferationGO:00481479.8LTA, MYC
4positive regulation of epidermal growth factor receptor signaling pathwayGO:00457429.8FASLG, MMP9
5positive regulation of DNA bindingGO:00433889.7MMP9, MYC
6positive regulation of apoptotic processGO:00430659.5FASLG, LTA, MMP9
7negative regulation of apoptotic processGO:00430669.5MMP9, MYC, TIMP1
8positive regulation of glial cell proliferationGO:00602529.4LTA, MYC
9positive regulation of cell proliferationGO:00082849.1FASLG, MYC, TIMP1
10response to growth factorGO:00708489.0FASLG, MYC

Molecular functions related to Chronic Venous Leg Ulcers according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:00051649.3FASLG, LTA
2cytokine activityGO:00051259.3FASLG, LTA, TIMP1

Sources for Chronic Venous Leg Ulcers

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet