MCID: CHY006
MIFTS: 48

Chylous Ascites malady

Rare diseases, Cardiovascular diseases categories
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Summaries for Chylous Ascites

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MalaCards based summary: Chylous Ascites, also known as congenital chylous ascites, is related to pancreatitis and liver cirrhosis, and has symptoms including ascitis, lymphedema and subcutaneous nodules/lipomas/tumefaction/swelling. An important gene associated with Chylous Ascites is SST (somatostatin). The compounds gelofusine and terlipressin have been mentioned in the context of this disorder. Affiliated tissues include liver, lymph node and heart, and related mouse phenotype digestive/alimentary.

Description from OMIM:46 208300

Aliases & Classifications for Chylous Ascites

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Sources:
42NIH Rare Diseases, 44Novoseek, 48Orphanet, 46OMIM, 62UMLS, 35MESH via Orphanet, 26ICD10 via Orphanet, 63UMLS via Orphanet
See all sources

Chylous Ascites, Aliases & Descriptions:

Name: Chylous Ascites 42 48 46 62
Congenital Chylous Ascites 42 62
 
Ascites Chylous 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Cardiovascular diseases


External Ids:

OMIM46 208300
MESH via Orphanet35 D002915
ICD10 via Orphanet26 I89.8
UMLS via Orphanet63 C0008732

Related Diseases for Chylous Ascites

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Graphical network of the top 20 diseases related to Chylous Ascites:



Diseases related to chylous ascites

Symptoms for Chylous Ascites

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Symptoms by clinical synopsis from OMIM:

208300

Clinical features from OMIM:

208300

Symptoms:

48 (show all 7)
  • ascitis
  • lymphedema
  • subcutaneous nodules/lipomas/tumefaction/swelling
  • glaucoma
  • intestinal/colonic anomaly
  • pancreatitis
  • neoplasms/tumors

HPO human phenotypes related to Chylous Ascites:

(show all 10)
id Description Frequency HPO Source Accession
1 lymphedema hallmark (90%) HP:0001004
2 ascites hallmark (90%) HP:0001541
3 abnormality of the skin typical (50%) HP:0000951
4 glaucoma occasional (7.5%) HP:0000501
5 pancreatitis occasional (7.5%) HP:0001733
6 abnormality of the intestine occasional (7.5%) HP:0002242
7 neoplasm occasional (7.5%) HP:0002664
8 autosomal recessive inheritance HP:0000007
9 glaucoma HP:0000501
10 chylous ascites HP:0012281

Drugs & Therapeutics for Chylous Ascites

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Drug clinical trials:

Search ClinicalTrials for Chylous Ascites

Search NIH Clinical Center for Chylous Ascites

Genetic Tests for Chylous Ascites

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Anatomical Context for Chylous Ascites

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MalaCards organs/tissues related to Chylous Ascites:

32
Liver, Lymph node, Heart, Colon, Testis, Pancreas, Kidney, Lung, Breast, Prostate, Testes, Small intestine, Ovary, T cells, B cells

Animal Models for Chylous Ascites or affiliated genes

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MGI Mouse Phenotypes related to Chylous Ascites:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.1ALB, SST

Publications for Chylous Ascites

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Articles related to Chylous Ascites:

(show top 50)    (show all 510)
idTitleAuthorsYear
1
Change of Chylous Ascites During Low-Density Lipoprotein Apheresis in a Patient With Idiopathic Nephrotic Syndrome. (25256915)
2014
2
Chylous ascites and chylothorax as presentation of a systemic progression of discoid lupus. (23364658)
2013
3
Chylous ascites after laparoscopic hand-assisted donor nephrectomy: Is it specific for the left-side? (23662011)
2013
4
Successful management of chylous ascites with total parenteral nutrition and octreotide in children. (24506391)
2013
5
Chylous ascites mimicking peritonitis after laparoscopic Roux-en-Y gastric bypass for morbid obesity. (20947450)
2012
6
Congenital chylous ascites and lymphedema in Down's syndrome. (22418947)
2012
7
Diagnosis and management of congenital neonatal chylous ascites. (23935276)
2012
8
Atraumatic chylous ascites: systematic review on symptoms and causes. (21398159)
2011
9
Cholelithiasis in a neonate with chylous ascites. (20182428)
2010
10
Congenital plaque-type glomuvenous malformation associated with chylous ascites. (21510024)
2010
11
Chylous ascites following laparoscopic adrenalectomy: case report and literature review. (21121441)
2010
12
Fatal chylous ascites, pericarditis and extensive venous thrombosis, due to an aggressive T cell non-Hodgkin lymphoma. (18679682)
2009
13
Coughing may lead to spontaneous chylothorax and chylous ascites. (21487566)
2007
14
Voluminous fetal chylous ascites: a case of complete spontaneous prenatal regression. (17135749)
2007
15
Chylous ascites following operation for para-aortic lymph node dissection in a patient with cervical cancer. (16515637)
2006
16
Chylous ascites: an unusual complication of percutaneous peritoneal catheter implantation. (17047246)
2006
17
Octreotide therapy for chylous ascites in a chronic dialysis patient. (16109079)
2005
18
A curious case of ascites. Chylous ascites caused by Kaposi's sarcoma. (12647476)
2003
19
The diagnosis and management of postoperative chylous ascites. (11792897)
2002
20
A case of primary chylous ascites resolved within 4 months by exclusive breast-feeding. (10936987)
2000
21
Chylous ascites: a rare complication of radical gastrectomy. (10829366)
2000
22
Chylous ascites caused by an occult pancreatic malignancy. (10868546)
1999
23
Ruptured lymphocele as a cause of chylous ascites: demonstration by lymphoscintigraphy. (9890497)
1999
24
An unusual case of gastroschisis with gallbladder evisceration and late postrepair chylous ascites. (9434035)
1997
25
Menetrier's disease: report of a transient case associated with chylous ascites. (9260809)
1997
26
Small cell carcinoma of the lung presenting as chylous ascites: a unique case. (9646203)
1997
27
Neonatal chylous ascites--report of three cases and review of the literature. (9099650)
1997
28
Rapid resolution of chylous ascites after liver transplantation using somatostatin analog and total parenteral nutrition. (8629307)
1996
29
Postcaval thrombosis and delayed shunt migration after pleuro-peritoneal venous shunting for concurrent chylothorax and chylous ascites in a dog. (9012108)
1996
30
Chylothorax and chylous ascites due to malignant lymphoma. (7725834)
1995
31
Chylous ascites in cats: nine cases (1978-1993). (7890576)
1994
32
Chylous ascites: A rare complication of liver cirrhosis. (17590704)
1993
33
Recessively determined chylous ascites--a case report and possible mouse model. (1342868)
1992
34
Chylous ascites in three dogs. (1537695)
1992
35
Aspergillus hepatosplenic abscesses and chylous ascites: successful treatment with fluconazole. (1341456)
1992
36
Chylous ascites: a rare complication of vagotomy. Case report. (1676311)
1991
37
Chylous ascites and continuous ambulatory peritoneal dialysis. (1745391)
1991
38
Chylous ascites as a presenting sign of prostatic adenocarcinoma. (2077299)
1990
39
Chronic lymphocytic leukemia presenting with massive chylous ascites. (2186618)
1990
40
Chylous ascites and encapsulating peritonitis: unusual complications of spontaneous bacterial peritonitis. (3578227)
1987
41
Chylous ascites following retroperitoneal lymph node dissection successfully treated with peritoneovenous shunt. (3682840)
1987
42
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 20-1986. A 68-year-old man with a malabsorption, chylous ascites, and mesenteric mass. (3702943)
1986
43
Sonographic appearance of chylous ascites. (6427292)
1984
44
Total parenteral nutrition in post-Warren shunt chylous ascites. (107924)
1979
45
Chylous ascites: the first reported surgical cure by direct ligation. (671201)
1978
46
Hairy cell leukemia with chylous ascites. (578227)
1977
47
CONGENITAL MULTILOCULAR MESENTERIC CYST WITH CHYLOUS ASCITES. (14208042)
1964
48
CHYLOUS ASCITES IN NEWBORN MICE. (14205977)
1964
49
Acute chylous ascites. (14470562)
1962
50
Chylous ascites: an analysis of its etiology. (14405264)
1960

Variations for Chylous Ascites

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Expression for genes affiliated with Chylous Ascites

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Expression patterns in normal tissues for genes affiliated with Chylous Ascites

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Pathways for genes affiliated with Chylous Ascites

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Compounds for genes affiliated with Chylous Ascites

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Compounds related to Chylous Ascites according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1gelofusine449.4ALB, SST
2terlipressin44 1110.3ALB, SST
3dtpa449.3SST, ALB
4captopril44 61 50 28 1113.3ALB, SST
5naloxone44 28 50 1112.2ALB, SST
6thyroxine44 2410.2SST, ALB
7histamine44 28 2411.1ALB, SST
8glucose449.1ALB, SST
9lactate449.0ALB, SST
10testosterone44 61 24 1111.8ALB, SST

GO Terms for genes affiliated with Chylous Ascites

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Cellular components related to Chylous Ascites according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055769.1ALB, SST
2extracellular spaceGO:0056158.8ALB, SST

Biological processes related to Chylous Ascites according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to nutrientGO:0075849.1ALB, SST

Products for genes affiliated with Chylous Ascites

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  • Antibodies
  • Proteins
  • Lysates

Sources for Chylous Ascites

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet