MCID: CHY006
MIFTS: 48

Chylous Ascites malady

Rare diseases, Cardiovascular diseases categories

Summaries for Chylous Ascites

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48OMIM, 34MalaCards
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MalaCards: Chylous Ascites, also known as congenital chylous ascites, is related to pancreatitis and liver cirrhosis, and has symptoms including neoplasms/tumors, ascitis and lymphedema. An important gene associated with Chylous Ascites is SST (somatostatin). The compounds gelofusine and terlipressin have been mentioned in the context of this disorder. Affiliated tissues include liver, lymph node and colon, and related mouse phenotype digestive/alimentary.

Description from OMIM:48 208300

Aliases & Classifications for Chylous Ascites

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44NIH Rare Diseases, 50Orphanet, 48OMIM, 63UMLS, 46Novoseek, 37MESH via Orphanet, 27ICD10 via Orphanet, 60SNOMED-CT via Orphanet, 64UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

chylous ascites 44 50 48 63
congenital chylous ascites 44 63
ascites chylous 46


External Ids:

OMIM48 208300
MESH via Orphanet37 D002915
ICD10 via Orphanet27 I89.8
SNOMED-CT via Orphanet60 52985009
UMLS via Orphanet64 C0008732

Related Diseases for Chylous Ascites

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Chylous Ascites:



Diseases related to chylous ascites

Symptoms for Chylous Ascites

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48OMIM, 50Orphanet
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Symptoms by clinical synopsis from OMIM:

208300

Clinical features from OMIM:

208300

Symptoms:

50 (show all 7)
  • neoplasms/tumors
  • ascitis
  • lymphedema
  • pancreatitis
  • glaucoma
  • intestinal/colonic anomaly
  • subcutaneous nodules/lipomas/tumefaction/swelling

Drugs & Therapeutics for Chylous Ascites

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Chylous Ascites

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Anatomical Context for Chylous Ascites

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34MalaCards
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MalaCards organs/tissues related to Chylous Ascites:

34
Liver, Lymph node, Colon, Heart, Testis, Pancreas, Breast, Testes, Lung, Prostate, Kidney, Ovary, Small intestine, B cells, T cells

Animal Models for Chylous Ascites or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Chylous Ascites:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.1ALB, SST

Publications for Chylous Ascites

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53PubMed
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Articles related to Chylous Ascites:

(show top 50)    (show all 494)
idTitleAuthorsYear
1
Chylous ascites and chylothorax as presentation of a systemic progression of discoid lupus. (23364658)
2013
2
Chylous ascites after laparoscopic hand-assisted donor nephrectomy: Is it specific for the left-side? (23662011)
2013
3
Chylous ascites mimicking peritonitis after laparoscopic Roux-en-Y gastric bypass for morbid obesity. (20947450)
2012
4
Congenital chylous ascites and lymphedema in Down's syndrome. (22418947)
2012
5
Diagnosis and management of congenital neonatal chylous ascites. (23935276)
2012
6
Atraumatic chylous ascites: systematic review on symptoms and causes. (21398159)
2011
7
Cholelithiasis in a neonate with chylous ascites. (20182428)
2010
8
Congenital plaque-type glomuvenous malformation associated with chylous ascites. (21510024)
2010
9
Chylous ascites following laparoscopic adrenalectomy: case report and literature review. (21121441)
2010
10
Fatal chylous ascites, pericarditis and extensive venous thrombosis, due to an aggressive T cell non-Hodgkin lymphoma. (18679682)
2009
11
Coughing may lead to spontaneous chylothorax and chylous ascites. (21487566)
2007
12
Voluminous fetal chylous ascites: a case of complete spontaneous prenatal regression. (17135749)
2007
13
Chylous ascites following operation for para-aortic lymph node dissection in a patient with cervical cancer. (16515637)
2006
14
A female with hemihypertrophy and chylous ascites - Klippel-Trenaunay syndrome or Proteus syndrome: a diagnostic dilemma. (16957479)
2006
15
Chylous ascites: an unusual complication of percutaneous peritoneal catheter implantation. (17047246)
2006
16
Octreotide therapy for chylous ascites in a chronic dialysis patient. (16109079)
2005
17
A curious case of ascites. Chylous ascites caused by Kaposi's sarcoma. (12647476)
2003
18
The diagnosis and management of postoperative chylous ascites. (11792897)
2002
19
A case of primary chylous ascites resolved within 4 months by exclusive breast-feeding. (10936987)
2000
20
Chylous ascites: a rare complication of radical gastrectomy. (10829366)
2000
21
Chylous ascites caused by an occult pancreatic malignancy. (10868546)
1999
22
Ruptured lymphocele as a cause of chylous ascites: demonstration by lymphoscintigraphy. (9890497)
1999
23
Successful management of chylous ascites after laparoscopic presacral neurectomy. (9782151)
1998
24
An unusual case of gastroschisis with gallbladder evisceration and late postrepair chylous ascites. (9434035)
1997
25
Menetrier's disease: report of a transient case associated with chylous ascites. (9260809)
1997
26
Small cell carcinoma of the lung presenting as chylous ascites: a unique case. (9646203)
1997
27
Neonatal chylous ascites--report of three cases and review of the literature. (9099650)
1997
28
Rapid resolution of chylous ascites after liver transplantation using somatostatin analog and total parenteral nutrition. (8629307)
1996
29
Postcaval thrombosis and delayed shunt migration after pleuro-peritoneal venous shunting for concurrent chylothorax and chylous ascites in a dog. (9012108)
1996
30
Chylothorax and chylous ascites due to malignant lymphoma. (7725834)
1995
31
Chylous ascites in cats: nine cases (1978-1993). (7890576)
1994
32
Chylous ascites: A rare complication of liver cirrhosis. (17590704)
1993
33
Recessively determined chylous ascites--a case report and possible mouse model. (1342868)
1992
34
Chylous ascites in three dogs. (1537695)
1992
35
Aspergillus hepatosplenic abscesses and chylous ascites: successful treatment with fluconazole. (1341456)
1992
36
Chylous ascites: a rare complication of vagotomy. Case report. (1676311)
1991
37
Chylous ascites and continuous ambulatory peritoneal dialysis. (1745391)
1991
38
Chylous ascites as a presenting sign of prostatic adenocarcinoma. (2077299)
1990
39
Chronic lymphocytic leukemia presenting with massive chylous ascites. (2186618)
1990
40
Chylous ascites and encapsulating peritonitis: unusual complications of spontaneous bacterial peritonitis. (3578227)
1987
41
Chylous ascites following retroperitoneal lymph node dissection successfully treated with peritoneovenous shunt. (3682840)
1987
42
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 20-1986. A 68-year-old man with a malabsorption, chylous ascites, and mesenteric mass. (3702943)
1986
43
Sonographic appearance of chylous ascites. (6427292)
1984
44
Total parenteral nutrition in post-Warren shunt chylous ascites. (107924)
1979
45
Chylous ascites: the first reported surgical cure by direct ligation. (671201)
1978
46
Hairy cell leukemia with chylous ascites. (578227)
1977
47
CONGENITAL MULTILOCULAR MESENTERIC CYST WITH CHYLOUS ASCITES. (14208042)
1964
48
CHYLOUS ASCITES IN NEWBORN MICE. (14205977)
1964
49
Acute chylous ascites. (14470562)
1962
50
Chylous ascites: an analysis of its etiology. (14405264)
1960

Variations for Chylous Ascites

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Expression for genes affiliated with Chylous Ascites

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Chylous Ascites

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Pathways for genes affiliated with Chylous Ascites

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Compounds for genes affiliated with Chylous Ascites

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46Novoseek, 12DrugBank, 62Tocris Bioscience, 52PharmGKB, 30IUPHAR, 25HMDB
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Compounds related to Chylous Ascites according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1gelofusine469.4ALB, SST
2terlipressin46 1210.3ALB, SST
3dtpa469.3SST, ALB
4captopril46 62 52 30 1213.3ALB, SST
5naloxone46 30 52 1212.2ALB, SST
6thyroxine46 2510.2SST, ALB
7histamine46 30 2511.1ALB, SST
8glucose469.1ALB, SST
9lactate469.0ALB, SST
10testosterone46 62 25 1211.8ALB, SST

GO Terms for genes affiliated with Chylous Ascites

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17Gene Ontology
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Cellular components related to Chylous Ascites according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055769.1ALB, SST
2extracellular spaceGO:0056158.8ALB, SST

Biological processes related to Chylous Ascites according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to nutrientGO:0075849.1ALB, SST

Products for genes affiliated with Chylous Ascites

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Chylous Ascites

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet