MCID: CCT002
MIFTS: 51

Cicatricial Pemphigoid malady

Categories: Rare diseases, Eye diseases, Skin diseases

Aliases & Classifications for Cicatricial Pemphigoid

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Sources:
11Disease Ontology, 13DISEASES, 29ICD10, 30ICD10 via Orphanet, 31ICD9CM, 38MeSH, 44NCIt, 47NIH Rare Diseases, 49Novoseek, 53Orphanet, 61SNOMED-CT, 67UMLS
See all MalaCards sources

Aliases & Descriptions for Cicatricial Pemphigoid:

Name: Cicatricial Pemphigoid 11 47 13
Benign Mucous Membrane Pemphigoid with Ocular Involvement 11 67
Pemphigoid, Benign Mucous Membrane 38 67
Ocular Pemphigoid 11 53
Cicatricial Pemphigoid with Ocular Involvement 11
 
Benign Mucous Membrance Pemphigoid 47
Benign Mucous Membrane Pemphigoid 11
Benign Mucosal Pemphigoid 47
Pemphigoid Cicatricial 49
Ocular Pemphigus 11

Classifications:

Orphanet: 53 
Rare eye diseases


External Ids:

Disease Ontology11 DOID:11656
ICD1029 L12.1, H13.3
ICD9CM31 694.6, 694.61
MeSH38 D010390
NCIt44 C34907
Orphanet53 ORPHA99922
ICD10 via Orphanet30 L12+, H13.3*

Summaries for Cicatricial Pemphigoid

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Disease Ontology:11 A bullous skin disease characterized by skin lesions and scaring and located in mucous membranes and located in skin.

MalaCards based summary: Cicatricial Pemphigoid, also known as benign mucous membrane pemphigoid with ocular involvement, is related to lichen sclerosus and ocular cicatricial pemphigoid, and has symptoms including exanthema, discharge from eye and coma blister. An important gene associated with Cicatricial Pemphigoid is COL17A1 (Collagen Type XVII Alpha 1 Chain), and among its related pathways are a6b1 and a6b4 Integrin signaling and Validated transcriptional targets of AP1 family members Fra1 and Fra2. Affiliated tissues include mucous membranes, skin and skin, and related mouse phenotypes are craniofacial and digestive/alimentary.

Wikipedia:70 Cicatricial pemphigoid (also known as \"Mucous Membrane Pemphigoid\", \"MMP\", \"Benign mucosal... more...

Related Diseases for Cicatricial Pemphigoid

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Diseases related to Cicatricial Pemphigoid via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 96)
idRelated DiseaseScoreTop Affiliating Genes
1lichen sclerosus30.0COL17A1, DST, ITGB4
2ocular cicatricial pemphigoid12.6
3brunsting-perry syndrome11.5
4giant ganglionic hyperplasia10.4COL17A1, DST
5submandibular gland cancer10.4COL17A1, DST
6bullous pemphigoid10.4
7tinea cruris10.3COL17A1, DST
8spinocerebellar ataxia 2310.3DST, ITGB4
9epidermolysis bullosa10.3
10cirrhotic cardiomyopathy10.3COL17A1, DST
118p11.2 deletion syndrome10.3LAMA3, LAMC2
12epidermolysis bullosa acquisita10.2
13epidermolysis bullosa, junctional, herlitz type10.2LAMA3, LAMC2
14gingivitis10.2
15laryngitis10.2
16geniculate herpes zoster10.2COL17A1, DST
17ankylosis10.2CD79A, SERPINH1
18artery disease10.1CD79A, SERPINH1
19rheumatoid arthritis10.1
20arthritis10.1
21psoriasis10.1CD79A, TNFRSF1B
22peptic esophagitis10.1CD79A, TNFRSF1B
23pemphigus10.1
24tetanus10.1CD79A, TNFRSF1B
25familial retinoblastoma10.1COL17A1, DST, ITGB4
26fetal erythroblastosis10.1CD79A, TNFRSF1B
27vaginal squamous tumor10.1CD79A, TNFRSF1B
28cataract10.1
29esophagitis10.1
30linear iga disease10.1
31salpingitis10.1CD79A, TNFRSF1B
32crest syndrome10.1CD79A, TNFRSF1B
33spondylosis10.0CD79A, TNFRSF1B
34pemphigus vulgaris10.0
35entropion10.0
36large cell acanthoma10.0ITGB4, LAMA3, SERPINH1
37malignant histiocytosis10.0CD79A, COL17A1, DST
38early congenital syphilis10.0CD79A, TNFRSF1B
39blood group incompatibility10.0CD79A, COL17A1, DST
40diabetic macular edema10.0CD79A, COL17A1, DST
41lacrimal system cancer10.0CD79A, TNFRSF1B
42conjunctivitis10.0
43achilles bursitis9.9CD79A, TNFRSF1B
44sternum lymphoma9.9CD79A, TNFRSF1B
45keratitis9.9
46erythema multiforme9.9
47lymphoma9.9
48corneal ulcer9.9
49lupus erythematosus9.9
50mesangial proliferative glomerulonephritis9.9CD79A, CFP

Comorbidity relations with Cicatricial Pemphigoid via Phenotypic Disease Network (PDN):


Corneal Ulcer

Graphical network of the top 20 diseases related to Cicatricial Pemphigoid:



Diseases related to cicatricial pemphigoid

Symptoms for Cicatricial Pemphigoid

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UMLS symptoms related to Cicatricial Pemphigoid:


exanthema, discharge from eye, coma blister

Drugs & Therapeutics for Cicatricial Pemphigoid

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Drugs for Cicatricial Pemphigoid (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Mycophenolic acidapprovedPhase 393924280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
2
Mycophenolate mofetilapproved, investigationalPhase 3939128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
3Immunosuppressive AgentsPhase 312770
4Antibiotics, AntitubercularPhase 36972
5Anti-Bacterial AgentsPhase 310884
6
rituximabapprovedPhase 1, Phase 21654174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
7
InfliximabapprovedPhase 1, Phase 2378170277-31-3
Synonyms:
 
Ig gamma-1 chain C region
Remicade
8
Riboflavinapproved, nutraceutical, vet_approvedPhase 1, Phase 216583-88-5493570
Synonyms:
(-)-Riboflavin
1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol
1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol
6,7-Dimethyl-9-D-ribitylisoalloxazine
6,7-Dimethyl-9-ribitylisoalloxazine
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-Benzo[g]pteridine-2,4(3H,10H)-dione
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine
7,8-Dimethyl-10-ribitylisoalloxazine
Beflavin
Beflavine
Benzo[g]pteridine riboflavin deriv.
E 101
E101
Flavaxin
Flavin BB
Flaxain
Food Yellow 15
 
Hyre
Lactobene
Lactoflavin
Lactoflavine
Ribipca
Ribocrisina
Riboderm
Riboflavina
Riboflavine
Riboflavinum
Ribosyn
Ribotone
Ribovel
Russupteridine yellow III
San Yellow B
Vitaflavine
Vitamin B2
Vitamin G
Vitasan B2
9
Folic Acidapproved, nutraceutical, vet_approvedPhase 1, Phase 2427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
10Antirheumatic AgentsPhase 1, Phase 210627
11Trace ElementsPhase 1, Phase 25802
12Vitamin B ComplexPhase 1, Phase 24229
13VitaminsPhase 1, Phase 25095
14Pharmaceutical SolutionsPhase 1, Phase 27793
15Dermatologic AgentsPhase 1, Phase 25674
16MicronutrientsPhase 1, Phase 25802
17Photosensitizing AgentsPhase 1, Phase 2476
18Gastrointestinal AgentsPhase 1, Phase 28109
19FolateNutraceuticalPhase 1, Phase 24279
20Vitamin B9NutraceuticalPhase 1, Phase 24279
21Vitamin B2NutraceuticalPhase 1, Phase 2165
22ImmunoglobulinsPhase 16045
23AntibodiesPhase 16045
24Autoantibodies126

Interventional clinical trials:

(show all 12)
idNameStatusNCT IDPhase
1Pharmacokinetics Study of Mycophenolic Acid in Patients With an Autoimmune Bullous Dermatose, Pemphigus or Cicatricial Pemphigoid.Not yet recruitingNCT02993133Phase 3
2Clinical Trial Evaluating Rituximab in Ocular Cicatricial PemphigoidCompletedNCT00584935Phase 1, Phase 2
3Limbal Epithelial Stem Cell Transplantation: a Phase II Multicenter TrialRecruitingNCT02318485Phase 2
4Use of Cross-linked Donor Corneas as Carriers for the Boston KeratoprosthesisRecruitingNCT01582880Phase 1, Phase 2
5Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet TransplantationAvailableNCT02149732Phase 1, Phase 2
6Topical Infliximab in Autoimmune Eyes With KeratoprosthesisEnrolling by invitationNCT02126020Phase 1, Phase 2
7The Improvement of Limbal Epithelial Culture Technique by Using Collagenase to Isolate Limbal Stem CellsUnknown statusNCT02202642Phase 1
8Topical Infliximab for Sterile Corneal MeltNot yet recruitingNCT02987686Phase 1
9Subconjunctival IVIg (Gamunex-C) Injection for Corneal Neovascularization and Inflammatory ConditionsWithdrawnNCT02042027Phase 1
10Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort StudyCompletedNCT00116090
11Genetic Susceptibility and Influence of the Microbiomae in Bullous PemphigoidRecruitingNCT02874079
12Immune Responses to Antigens in Non-infectious Eye Inflammatory DiseasesEnrolling by invitationNCT00357071

Search NIH Clinical Center for Cicatricial Pemphigoid


Cochrane evidence based reviews: pemphigoid, benign mucous membrane

Genetic Tests for Cicatricial Pemphigoid

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Anatomical Context for Cicatricial Pemphigoid

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MalaCards organs/tissues related to Cicatricial Pemphigoid:

35
Skin, Eye, Testes, Lung, Neutrophil, T cells, Pancreas

FMA organs/tissues related to Cicatricial Pemphigoid:

17
Mucous membranes, Skin

Animal Models for Cicatricial Pemphigoid or affiliated genes

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MGI Mouse Phenotypes related to Cicatricial Pemphigoid:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.7ITGB4, LAMA3, LAMC2, SERPINH1, TNFRSF1B
2MP:00053818.6ITGB4, LAMA3, LAMC2, SERPINH1, TNFRSF1B

Publications for Cicatricial Pemphigoid

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Articles related to Cicatricial Pemphigoid:

(show top 50)    (show all 431)
idTitleAuthorsYear
1
IgM ocular cicatricial pemphigoid: a unique insight into the immune system. (26632795)
2015
2
Membrane array analysis of tear proteins in ocular cicatricial pemphigoid. (21552176)
2011
3
Cicatricial pemphigoid in accompany with rheumatoid arthritis: a case report. (21180281)
2010
4
Early onset childhood cicatricial pemphigoid: a case report and review of the literature. (20537062)
2010
5
Cyclophosphamide and amniotic membrane transplantation in the management of ocular disease in a case of antiepiligrin cicatricial pemphigoid. (19747320)
2009
6
Intravenous immunoglobulin therapy for refractory ocular cicatricial pemphigoid: case report. (18724167)
2008
7
Ocular involvement in anti-epiligrin cicatricial pemphigoid. (17191196)
2006
8
Cicatricial pemphigoid with widespread bullous eruption. (17040507)
2006
9
Cicatricial pemphigoid and dry eye. (16020349)
2005
10
Human mast cell subtypes in conjunctiva of patients with atopic keratoconjunctivitis, ocular cicatricial pemphigoid and Stevens-Johnson syndrome. (14566647)
2003
11
Role of connective tissue growth factor in the pathogenesis of conjunctival scarring in ocular cicatricial pemphigoid. (12714635)
2003
12
Cicatricial pemphigoid--a case report. (17664749)
2001
13
Interleukin 1 components in cicatricial pemphigoid. Role in intravenous immunoglobulin therapy. (11448121)
2001
14
Image interpretation session: 1999. Benign mucous membrane pemphigoid (cicatricial pemphigoid). (10682788)
2000
15
Chronic graft-vs.-host disease with severe cicatrizing conjunctivitis mimicking cicatricial pemphigoid. (10886174)
2000
16
Anti-epiligrin cicatricial pemphigoid with antibodies against the gamma2 subunit of laminin 5. (10052402)
1999
17
Linear IgA dermatosis mimicking ocular cicatricial pemphigoid. (10555732)
1999
18
Treatment of ocular cicatricial pemphigoid with intravenous gammaglobulin. (9689316)
1998
19
Conjunctival scarring after eyelid surgery as first sign of ocular cicatricial pemphigoid. (9076789)
1997
20
Ocular cicatricial pemphigoid and ocular manifestations of pemphigus vulgaris. (9269598)
1997
21
Four Japanese patients with cicatricial pemphigoid showing both IgG and IgA antibodies against the 180 kDa bullous pemphigoid antigen. (9292089)
1997
22
Cicatricial pemphigoid treated with intravenous immunoglobulin. (9349361)
1997
23
Management of airway obstruction in cicatricial pemphigoid. (8699892)
1996
24
Progression of disease in ocular cicatricial pemphigoid. (8703876)
1996
25
Cicatricial pemphigoid autoantibodies react with multiple sites on the BP180 extracellular domain. (8592065)
1996
26
Barium studies in esophageal cicatricial pemphigoid. (7787730)
1995
27
Ocular cicatricial pemphigoid. A case report of monozygotic twins discordant for the disease. (7864752)
1995
28
Autoantibodies from patients with cicatricial pemphigoid target different sites in epidermal basement membrane. (7861004)
1995
29
Retractor plication for lower lid entropion in ocular cicatricial pemphigoid. (8333940)
1993
30
Vulvar cicatricial pemphigoid as a lichen sclerosus imitator. A case report. (1619612)
1992
31
Results of buccal mucosal grafting for patients with medically controlled ocular cicatricial pemphigoid. (1565450)
1992
32
Salt-split human skin substrate for the immunofluorescent screening of serum from patients with cicatricial pemphigoid and a new method of immunoprecipitation with IgA antibodies. (1869683)
1991
33
Cicatricial pemphigoid. Identification of two distinct sets of epidermal antigens by IgA and IgG class circulating autoantibodies. (2241199)
1990
34
Immunopathology of cicatricial pemphigoid affecting the conjunctiva. (1979435)
1990
35
Mast cells in conjunctiva affected by cicatricial pemphigoid. (2671849)
1989
36
Cicatricial pemphigoid of upper digestive and respiratory tracts. (3552189)
1987
37
Cicatricial pemphigoid. A case of onset at age 5. (3511219)
1986
38
Localized cicatricial pemphigoid (Brunsting-Perry syndrome). (3536333)
1986
39
Ocular cicatricial pemphigoid with granular IgA and complement deposition. (3904684)
1985
40
Occurrence of cicatricial pemphigoid and leiomyosarcoma in a psoriatic patient. (3891438)
1985
41
Cicatricial pemphigoid of the vulva. (3895957)
1985
42
Childhood cicatricial pemphigoid with linear IgA deposits: a case report. (2413697)
1985
43
Cicatricial pemphigoid and erythema multiforme. (6337967)
1983
44
Juvenile cicatricial pemphigoid with persistent bullous eruption: a new entity? (6754929)
1982
45
Case 32, part 2. Cicatricial pemphigoid (benign mucous membrane pemphigoid). (6999138)
1980
46
Association of cicatricial pemphigoid and rheumatoid arthritis. (367284)
1979
47
Enigma of ocular cicatricial pemphigoid. A comparative study of clinical and immunological findings. (398602)
1979
48
Immunologic aspects of cicatricial pemphigoid. (1090180)
1975
49
Letter: Cicatricial pemphigoid. (4814935)
1974
50
Pemphigus-like antibodies in cicatricial pemphigoid. (4592565)
1974

Variations for Cicatricial Pemphigoid

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Expression for genes affiliated with Cicatricial Pemphigoid

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Search GEO for disease gene expression data for Cicatricial Pemphigoid.

Pathways for genes affiliated with Cicatricial Pemphigoid

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Pathways related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

(show all 12)
idSuper pathwaysScoreTop Affiliating Genes
19.7COL17A1, ITGB4
29.7ITGB4, LAMA3
39.6LAMA3, LAMC2
49.4LAMC2, TNFRSF1B
5
Show member pathways
9.2ITGB4, LAMA3, LAMC2
6
Show member pathways
9.2ITGB4, LAMA3, LAMC2
79.2ITGB4, LAMA3, LAMC2
8
Show member pathways
8.5COL17A1, DST, ITGB4, LAMA3, LAMC2
98.5COL17A1, DST, ITGB4, LAMA3, LAMC2
10
Show member pathways
8.4CD79A, COL17A1, ITGB4, LAMA3, LAMC2
11
Show member pathways
7.8COL17A1, DST, ITGB4, LAMA3, LAMC2, SERPINH1
12
Show member pathways
7.8COL17A1, DST, ITGB4, LAMA3, LAMC2, SERPINH1

GO Terms for genes affiliated with Cicatricial Pemphigoid

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Cellular components related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1basement membraneGO:00056049.9COL17A1, DST, LAMA3
2hemidesmosomeGO:00300569.9COL17A1, DST, ITGB4
3cell leading edgeGO:00312529.9DST, ITGB4
4endoplasmic reticulum lumenGO:00057888.9CFP, COL17A1, SERPINH1
5membrane raftGO:00451218.6CD79A, SERPINH1, TNFRSF1B
6extracellular regionGO:00055767.9CFP, COL17A1, LAMA3, LAMC2, TNFRSF1B

Biological processes related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell motilityGO:004887010.0DST, ITGB4
2epidermis developmentGO:00085449.5COL17A1, LAMA3, LAMC2
3hemidesmosome assemblyGO:00315819.3COL17A1, ITGB4, LAMA3, LAMC2
4extracellular matrix organizationGO:00301989.2ITGB4, LAMA3, LAMC2
5cell adhesionGO:00071558.8DST, ITGB4, LAMA3, LAMC2

Sources for Cicatricial Pemphigoid

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
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33KEGG
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40MGI
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66Tumor Gene Family of Databases
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