MCID: CCT002
MIFTS: 50

Cicatricial Pemphigoid malady

Categories: Rare diseases, Eye diseases, Skin diseases

Aliases & Classifications for Cicatricial Pemphigoid

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Sources:
11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 32ICD9CM, 39MeSH, 45NCIt, 48NIH Rare Diseases, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS
See all MalaCards sources

Aliases & Descriptions for Cicatricial Pemphigoid:

Name: Cicatricial Pemphigoid 11 48 13
Benign Mucous Membrane Pemphigoid with Ocular Involvement 11 68
Pemphigoid, Benign Mucous Membrane 39 68
Ocular Pemphigoid 11 54
Cicatricial Pemphigoid with Ocular Involvement 11
 
Benign Mucous Membrance Pemphigoid 48
Benign Mucous Membrane Pemphigoid 11
Benign Mucosal Pemphigoid 48
Pemphigoid Cicatricial 50
Ocular Pemphigus 11

Classifications:

Orphanet: 54 
Rare eye diseases


External Ids:

Disease Ontology11 DOID:11656
ICD1030 L12.1, H13.3
ICD9CM32 694.6, 694.61
MeSH39 D010390
NCIt45 C34907
Orphanet54 ORPHA99922
ICD10 via Orphanet31 L12+, H13.3*

Summaries for Cicatricial Pemphigoid

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NIH Rare Diseases:48 Cicatricial pemphigoid is a rare, chronic, blistering and scarring disease that affects the oral and ocular mucosa. other mucosal sites that might be affected include the nasopharnyx, larynx, genitalia, rectum, and esophagus. the condition usually begins in late adulthood (e.g. 50's or 60's), affects more women than men, and has a variable prognosis. scarring of the affected  mucosa of the eye may lead to blindness and tends to be the most feared complication. a combination of environmental and genetic factors appear to play a role in the susceptibility of developing cicatricial pemphigoid. although the specific causes of this condition have not been identified, it is considered an autoimmune disease that is characterized by the production of autoantibodies against basement membrane zone antigens such as bp180, bp230, and laminin 5.  treatment is dependent on the person's specific symptoms. last updated: 11/14/2014

MalaCards based summary: Cicatricial Pemphigoid, also known as benign mucous membrane pemphigoid with ocular involvement, is related to rheumatoid arthritis and ocular cicatricial pemphigoid. An important gene associated with Cicatricial Pemphigoid is COL17A1 (Collagen Type XVII Alpha 1 Chain), and among its related pathways are a6b1 and a6b4 Integrin signaling and Validated transcriptional targets of AP1 family members Fra1 and Fra2. Affiliated tissues include mucous membranes, skin and skin, and related mouse phenotypes are Decreased viability and Increased shRNA abundance.

Disease Ontology:11 A bullous skin disease characterized by skin lesions and scaring and located in mucous membranes and located in skin.

Wikipedia:71 Cicatricial pemphigoid (also known as \"Mucous Membrane Pemphigoid\", \"MMP\", \"Benign mucosal... more...

Related Diseases for Cicatricial Pemphigoid

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Diseases related to Cicatricial Pemphigoid via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 101)
idRelated DiseaseScoreTop Affiliating Genes
1rheumatoid arthritis29.8CD79A, HLA-DQB1, SERPINH1, TNFRSF1B
2ocular cicatricial pemphigoid12.6
3brunsting-perry syndrome11.5
4bullous pemphigoid10.4
5epidermolysis bullosa10.3
6epidermolysis bullosa acquisita10.2
7peptidic growth factors deficiency10.2COL17A1, DST
8dyskinesia of esophagus10.2COL17A1, DST
9spinocerebellar ataxia 2310.2DST, ITGB4
10gingivitis10.2
11laryngitis10.2
12vulvovaginal candidiasis10.2CD79A, SERPINH1
13lin-gettig syndrome10.1COL17A1, HLA-DQB1
14artery disease10.1CD79A, SERPINH1
15arthritis10.1
16blackwater fever10.1CD79A, CFP
17linear hamartoma syndrome10.1COL17A1, DST, ITGB4
18nemaline myopathy 910.1COL17A1, DST, ITGB4
19primary lacrimal atrophy10.1CD79A, TNFRSF1B
20intraocular retinoblastoma10.1COL17A1, DST, ITGB4
21pneumocystosis10.1CD79A, TNFRSF1B
22pemphigus10.1
23thrombophlebitis migrans10.1CD79A, TNFRSF1B
24angiokeratoma10.1CD79A, CFP
25good syndrome10.1CD79A, HLA-DQB1
26clostridium difficile colitis10.1CD79A, HLA-DQB1
27cataract10.1
28mucositis10.1
29esophagitis10.1
30linear iga disease10.1
31conjunctival vascular disease10.1CD79A, TNFRSF1B
32oral cavity cancer10.1CD79A, COL17A1, DST
33inclusion conjunctivitis10.0CD79A, TNFRSF1B
34pompholyx10.0CD79A, COL17A1, DST
3546,xy partial gonadal dysgenesis10.0LAMA3, LAMC2
36epidermolysis bullosa, junctional, non-herlitz type10.0LAMA3, LAMC2
37bronchiolitis10.0CD79A, CFP
38cryptococcosis10.0HLA-DQB1, TNFRSF1B
39pemphigus vulgaris10.0
40entropion10.0
41acinic cell breast carcinoma10.0CD79A, TNFRSF1B
42anaerobic meningitis10.0CD79A, HLA-DQB1
43folinic acid-responsive seizures10.0COL17A1, DST, HLA-DQB1
44newcastle disease10.0CD79A, TNFRSF1B
45peripheral nervous system neoplasm10.0COL17A1, DST
46conjunctivitis9.9
47lipoblastoma9.9CD79A, COL17A1, DST, ITGB4
48hypertrophic elongation of cervix9.9CD79A, TNFRSF1B
49barbiturate abuse9.9CD79A, HLA-DQB1
50atypical autism9.9CD79A, COL17A1, DST, LAMA3

Comorbidity relations with Cicatricial Pemphigoid via Phenotypic Disease Network (PDN):


Corneal Ulcer

Graphical network of the top 20 diseases related to Cicatricial Pemphigoid:



Diseases related to cicatricial pemphigoid

Symptoms & Phenotypes for Cicatricial Pemphigoid

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GenomeRNAi Phenotypes related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00381-A-19.9CD79A, HLA-DQB1, SERPINH1
2GR00327-A9.5CD79A, DST, HLA-DQB1, SERPINH1

MGI Mouse Phenotypes related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.0ITGB4, LAMA3, LAMC2, SERPINH1, TNFRSF1B
2MP:00053678.8CD79A, HLA-DQB1, ITGB4, LAMC2, TNFRSF1B
3MP:00053818.4HLA-DQB1, ITGB4, LAMA3, LAMC2, SERPINH1, TNFRSF1B
4MP:00053877.7CD79A, CFP, HLA-DQB1, ITGB4, LAMA3, LAMC2
5MP:00053887.6HLA-DQB1, ITGB4, LAMA3, LAMC2, SERPINH1, TNFRSF1B

Drugs & Therapeutics for Cicatricial Pemphigoid

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Drugs for Cicatricial Pemphigoid (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Mycophenolic acidapprovedPhase 395224280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
2
Mycophenolate mofetilapproved, investigationalPhase 3952128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
3Immunosuppressive AgentsPhase 313086
4Antibiotics, AntitubercularPhase 37180
5Anti-Bacterial AgentsPhase 311226
6
rituximabapprovedPhase 1, Phase 21692174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
7
InfliximabapprovedPhase 1, Phase 2392170277-31-3
Synonyms:
 
Ig gamma-1 chain C region
Remicade
8
Riboflavinapproved, nutraceutical, vet_approvedPhase 1, Phase 217483-88-5493570
Synonyms:
(-)-Riboflavin
1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol
1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol
6,7-Dimethyl-9-D-ribitylisoalloxazine
6,7-Dimethyl-9-ribitylisoalloxazine
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-Benzo[g]pteridine-2,4(3H,10H)-dione
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine
7,8-Dimethyl-10-ribitylisoalloxazine
Beflavin
Beflavine
Benzo[g]pteridine riboflavin deriv.
E 101
E101
Flavaxin
Flavin BB
Flaxain
Food Yellow 15
 
Hyre
Lactobene
Lactoflavin
Lactoflavine
Ribipca
Ribocrisina
Riboderm
Riboflavina
Riboflavine
Riboflavinum
Ribosyn
Ribotone
Ribovel
Russupteridine yellow III
San Yellow B
Vitaflavine
Vitamin B2
Vitamin G
Vitasan B2
9
Folic Acidapproved, nutraceutical, vet_approvedPhase 1, Phase 2439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
10Antirheumatic AgentsPhase 1, Phase 210956
11Trace ElementsPhase 1, Phase 26001
12Vitamin B ComplexPhase 1, Phase 24337
13VitaminsPhase 1, Phase 25282
14Pharmaceutical SolutionsPhase 1, Phase 28192
15Dermatologic AgentsPhase 1, Phase 25806
16MicronutrientsPhase 1, Phase 26001
17Photosensitizing AgentsPhase 1, Phase 2492
18Gastrointestinal AgentsPhase 1, Phase 28402
19FolateNutraceuticalPhase 1, Phase 24392
20Vitamin B9NutraceuticalPhase 1, Phase 24392
21Vitamin B2NutraceuticalPhase 1, Phase 2174
22ImmunoglobulinsPhase 16394
23AntibodiesPhase 16394
24Autoantibodies130

Interventional clinical trials:

(show all 12)
idNameStatusNCT IDPhase
1Pharmacokinetics Study of Mycophenolic Acid in Patients With an Autoimmune Bullous Dermatose, Pemphigus or Cicatricial Pemphigoid.Not yet recruitingNCT02993133Phase 3
2Clinical Trial Evaluating Rituximab in Ocular Cicatricial PemphigoidCompletedNCT00584935Phase 1, Phase 2
3Limbal Epithelial Stem Cell Transplantation: a Phase II Multicenter TrialRecruitingNCT02318485Phase 2
4Use of Cross-linked Donor Corneas as Carriers for the Boston KeratoprosthesisRecruitingNCT01582880Phase 1, Phase 2
5Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet TransplantationAvailableNCT02149732Phase 1, Phase 2
6Topical Infliximab in Autoimmune Eyes With KeratoprosthesisWithdrawnNCT02126020Phase 1, Phase 2
7The Improvement of Limbal Epithelial Culture Technique by Using Collagenase to Isolate Limbal Stem CellsUnknown statusNCT02202642Phase 1
8Topical Infliximab for Sterile Corneal MeltNot yet recruitingNCT02987686Phase 1
9Subconjunctival IVIg (Gamunex-C) Injection for Corneal Neovascularization and Inflammatory ConditionsWithdrawnNCT02042027Phase 1
10Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort StudyCompletedNCT00116090
11Genetic Susceptibility and Influence of the Microbiomae in Bullous PemphigoidRecruitingNCT02874079
12Immune Responses to Antigens in Non-infectious Eye Inflammatory DiseasesEnrolling by invitationNCT00357071

Search NIH Clinical Center for Cicatricial Pemphigoid


Cochrane evidence based reviews: pemphigoid, benign mucous membrane

Genetic Tests for Cicatricial Pemphigoid

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Anatomical Context for Cicatricial Pemphigoid

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MalaCards organs/tissues related to Cicatricial Pemphigoid:

36
Skin, Eye, Testes, Lung, Neutrophil, T cells, Pancreas

FMA organs/tissues related to Cicatricial Pemphigoid:

17
Mucous membranes, Skin

Publications for Cicatricial Pemphigoid

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Articles related to Cicatricial Pemphigoid:

(show top 50)    (show all 431)
idTitleAuthorsYear
1
Clinical features and in vivo confocal microscopy assessment in 12 patients with ocular cicatricial pemphigoid. (27275431)
2016
2
Update on ocular cicatricial pemphigoid and emerging treatments. (26708362)
2016
3
Autoimmune bullous diseases with skin and eye involvement: Cicatricial pemphigoid, pemphigus vulgaris, and pemphigus paraneoplastica. (26903186)
2016
4
Characteristics of patients with ocular cicatricial pemphigoid referred to major tertiary hospital. (25863854)
2015
5
Esophageal Cicatricial Pemphigoid as an Isolated Involvement Treated with Mycophenolate Mofetil. (26557393)
2015
6
NGF Modulates trkANGFR/p75NTR in I+SMA-Expressing Conjunctival Fibroblasts from Human Ocular Cicatricial Pemphigoid (OCP). (26569118)
2015
7
Cicatricial pemphigoid vegetans in a Polish woman. (26147045)
2015
8
IgM ocular cicatricial pemphigoid: a unique insight into the immune system. (26632795)
2015
9
Low-dose pulsed intravenous cyclophosphamide for severe ocular cicatricial pemphigoid in elderly patients. (25014147)
2014
10
Neutrophil collagenase, gelatinase, and myeloperoxidase in tears of patients with stevens-johnson syndrome and ocular cicatricial pemphigoid. (23962653)
2014
11
Remission of anti-epiligrin cicatricial pemphigoid after excision of cervical adenocarcinoma. (24766621)
2014
12
Coexistence of ocular cicatricial pemphigoid with Stevens Johnson syndrome. (23826544)
2013
13
Brunsting-perry type cicatricial pemphigoid with IgG autoantibodies to LAD-1. (24124894)
2013
14
Outcomes of cataract surgery in ocular cicatricial pemphigoid. (23941520)
2013
15
Hypopharyngeal presentation of cicatricial pemphigoid: videofluorographic and direct laryngoscopic findings. (23442384)
2013
16
Polymicrobial and microsporidial keratitis in a patient using Boston scleral contact lens for Sjogren's syndrome and ocular cicatricial pemphigoid. (23123433)
2013
17
A case of cicatricial pemphigoid of the larynx successfully treated with plasmapheresis therapy. (24170474)
2013
18
The frequency of other autoimmune disorders in patients with ocular cicatricial pemphigoid. (21595864)
2012
19
Ocular cicatricial pemphigoid masquerading as chronic conjunctivitis: a case report. (23269857)
2012
20
Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda. (23118521)
2012
21
Ocular and oral mucous membrane pemphigoid (cicatricial pemphigoid). (22137224)
2012
22
Profile of local interleukin expression in a cohort of ocular cicatricial pemphigoid patients. (23081979)
2012
23
Membrane array analysis of tear proteins in ocular cicatricial pemphigoid. (21552176)
2011
24
Cicatricial pemphigoid of the scalp mimicking discoid lupus erythematosus. (21920254)
2011
25
Pentoxifylline (anti-tumor necrosis factor drug): effective adjuvant therapy in the control of ocular cicatricial pemphigoid. (21279976)
2011
26
Peripheral ulcerative keratitis after cataract surgery in a patient with ocular cicatricial pemphigoid. (21822128)
2011
27
Ocular cicatricial pemphigoid: a review of clinical features, immunopathology, differential diagnosis, and current management. (21958173)
2011
28
Recalcitrant cicatricial pemphigoid treated with the anti-TNF-alpha agent etanercept. (20120429)
2010
29
Cicatricial pemphigoid in accompany with rheumatoid arthritis: a case report. (21180281)
2010
30
Scleral lenses and ocular cicatricial pemphigoid. (20697280)
2010
31
Transnasal endoscopy in a patient with cicatricial pemphigoid. (20524762)
2010
32
Early onset childhood cicatricial pemphigoid: a case report and review of the literature. (20537062)
2010
33
A tooth for an eye: cicatricial pemphigoid and the osteo-odonto-keratoprosthesis. (20956670)
2010
34
Anterior lamellar excision and laissez-faire healing for aberrant lashes in ocular cicatricial pemphigoid. (19911023)
2010
35
Transscleral diode laser cyclophotocoagulation and ocular cicatricial pemphigoid. (20635815)
2010
36
Combination of rituximab and intravenous immunoglobulin for recalcitrant ocular cicatricial pemphigoid: a preliminary report. (20045562)
2010
37
Laser light may improve the symptoms of oral lesions of cicatricial pemphigoid: a case report. (19878031)
2009
38
Multiple mucosal involvement in cicatricial pemphigoid. (20161882)
2009
39
Transscleral diode laser cyclophotocoagulation in a patient with ocular cicatricial pemphigoid. (19928727)
2009
40
T-helper 17 lymphocytes in ocular cicatricial pemphigoid. (19641634)
2009
41
Ocular cicatricial pemphigoid: the role of scleral lenses in disease management. (19770718)
2009
42
Cyclophosphamide and amniotic membrane transplantation in the management of ocular disease in a case of antiepiligrin cicatricial pemphigoid. (19747320)
2009
43
Combination treatment of intravenous immunoglobulin and cultivated oral mucosal epithelial transplantation for ocular cicatricial pemphigoid. (21686527)
2009
44
Ocular manifestations in a case of childhood cicatricial pemphigoid. (18609489)
2008
45
Ocular cicatricial pemphigoid. (18762085)
2008
46
Intravenous immunoglobulin therapy for refractory ocular cicatricial pemphigoid: case report. (18724167)
2008
47
A quick and simple serum test to differentiate bullous pemphigoid, epidermolysis bullosa acquisita, and anti-epiligrin cicatricial pemphigoid. (18718187)
2008
48
Exacerbation of undiagnosed ocular cicatricial pemphigoid after repair of involutional entropion. (18356734)
2008
49
Two cases of anti-epiligrin cicatricial pemphigoid with and without associated malignancy. (18779887)
2008
50
Brunsting-Perry cicatricial pemphigoid associated with autoantibodies to the C-terminal domain of BP180. (18637895)
2008

Variations for Cicatricial Pemphigoid

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Expression for genes affiliated with Cicatricial Pemphigoid

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Search GEO for disease gene expression data for Cicatricial Pemphigoid.

Pathways for genes affiliated with Cicatricial Pemphigoid

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Pathways related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

(show all 11)
idSuper pathwaysScoreTop Affiliating Genes
19.8COL17A1, ITGB4
29.7ITGB4, LAMA3
39.4LAMC2, TNFRSF1B
4
Show member pathways
9.3ITGB4, LAMA3, LAMC2
5
Show member pathways
9.3ITGB4, LAMA3, LAMC2
6
Show member pathways
9.3ITGB4, LAMA3, LAMC2
7
Show member pathways
9.2HLA-DQB1, LAMA3, LAMC2
8
Show member pathways
8.6COL17A1, DST, ITGB4, LAMA3, LAMC2
9
Show member pathways
8.6CD79A, COL17A1, ITGB4, LAMA3, LAMC2
10
Show member pathways
8.1COL17A1, DST, ITGB4, LAMA3, LAMC2, SERPINH1
11
Show member pathways
8.1COL17A1, DST, ITGB4, LAMA3, LAMC2, SERPINH1

GO Terms for genes affiliated with Cicatricial Pemphigoid

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Cellular components related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell leading edgeGO:003125210.4DST, ITGB4
2hemidesmosomeGO:003005610.0COL17A1, DST, ITGB4
3basement membraneGO:00056049.7COL17A1, DST, LAMA3, LAMC2
4endoplasmic reticulum lumenGO:00057889.4CFP, COL17A1, SERPINH1
5membrane raftGO:00451219.0CD79A, SERPINH1, TNFRSF1B

Biological processes related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell motilityGO:004887010.3DST, ITGB4
2epidermis developmentGO:000854410.0COL17A1, LAMA3, LAMC2
3cell adhesionGO:00071559.6DST, ITGB4, LAMA3, LAMC2
4extracellular matrix organizationGO:00301989.5ITGB4, LAMA3, LAMC2
5hemidesmosome assemblyGO:00315819.0COL17A1, ITGB4, LAMA3, LAMC2

Sources for Cicatricial Pemphigoid

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet