MCID: CCT002
MIFTS: 51

Cicatricial Pemphigoid malady

Categories: Rare diseases, Eye diseases, Skin diseases

Aliases & Classifications for Cicatricial Pemphigoid

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Sources:
11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 32ICD9CM, 39MeSH, 45NCIt, 48NIH Rare Diseases, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS
See all MalaCards sources

Aliases & Descriptions for Cicatricial Pemphigoid:

Name: Cicatricial Pemphigoid 11 48 13
Benign Mucous Membrane Pemphigoid with Ocular Involvement 11 68
Pemphigoid, Benign Mucous Membrane 39 68
Ocular Pemphigoid 11 54
Cicatricial Pemphigoid with Ocular Involvement 11
 
Benign Mucous Membrance Pemphigoid 48
Benign Mucous Membrane Pemphigoid 11
Benign Mucosal Pemphigoid 48
Pemphigoid Cicatricial 50
Ocular Pemphigus 11

Classifications:

Orphanet: 54 
Rare eye diseases


External Ids:

Disease Ontology11 DOID:11656
ICD1030 L12.1, H13.3
ICD9CM32 694.6, 694.61
MeSH39 D010390
NCIt45 C34907
Orphanet54 ORPHA99922
ICD10 via Orphanet31 L12+, H13.3*

Summaries for Cicatricial Pemphigoid

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NIH Rare Diseases:48 Cicatricial pemphigoid is a rare, chronic, blistering and scarring disease that affects the oral and ocular mucosa. Other mucosal sites that might be affected include the nasopharnyx, larynx, genitalia, rectum, and esophagus. The condition usually begins in late adulthood (e.g. 50's or 60's), affects more women than men, and has a variable prognosis. Scarring of the affected  mucosa of the eye may lead to blindness and tends to be the most feared complication. A combination of environmental and genetic factors appear to play a role in the susceptibility of developing cicatricial pemphigoid. Although the specific causes of this condition have not been identified, it is considered an autoimmune disease that is characterized by the production of autoantibodies against basement membrane zone antigens such as BP180, BP230, and laminin 5.  Treatment is dependent on the person's specific symptoms. Last updated: 11/14/2014

MalaCards based summary: Cicatricial Pemphigoid, also known as benign mucous membrane pemphigoid with ocular involvement, is related to lichen sclerosus and ocular cicatricial pemphigoid, and has symptoms including exanthema, discharge from eye and coma blister. An important gene associated with Cicatricial Pemphigoid is COL17A1 (Collagen Type XVII Alpha 1 Chain), and among its related pathways are a6b1 and a6b4 Integrin signaling and Validated transcriptional targets of AP1 family members Fra1 and Fra2. Affiliated tissues include mucous membranes, skin and skin, and related mouse phenotypes are Increased shRNA abundance and craniofacial.

Disease Ontology:11 A bullous skin disease characterized by skin lesions and scaring and located in mucous membranes and located in skin.

Wikipedia:71 Cicatricial pemphigoid (also known as \"Mucous Membrane Pemphigoid\", \"MMP\", \"Benign mucosal... more...

Related Diseases for Cicatricial Pemphigoid

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Diseases related to Cicatricial Pemphigoid via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 96)
idRelated DiseaseScoreTop Affiliating Genes
1lichen sclerosus30.0COL17A1, DST, ITGB4
2ocular cicatricial pemphigoid12.6
3brunsting-perry syndrome11.5
4giant ganglionic hyperplasia10.4COL17A1, DST
5submandibular gland cancer10.4COL17A1, DST
6bullous pemphigoid10.4
7tinea cruris10.3COL17A1, DST
8spinocerebellar ataxia 2310.3DST, ITGB4
9epidermolysis bullosa10.3
10cirrhotic cardiomyopathy10.3COL17A1, DST
118p11.2 deletion syndrome10.3LAMA3, LAMC2
12epidermolysis bullosa acquisita10.2
13epidermolysis bullosa, junctional, herlitz type10.2LAMA3, LAMC2
14gingivitis10.2
15laryngitis10.2
16geniculate herpes zoster10.2COL17A1, DST
17ankylosis10.2CD79A, SERPINH1
18artery disease10.1CD79A, SERPINH1
19rheumatoid arthritis10.1
20arthritis10.1
21psoriasis10.1CD79A, TNFRSF1B
22peptic esophagitis10.1CD79A, TNFRSF1B
23pemphigus10.1
24tetanus10.1CD79A, TNFRSF1B
25familial retinoblastoma10.1COL17A1, DST, ITGB4
26fetal erythroblastosis10.1CD79A, TNFRSF1B
27vaginal squamous tumor10.1CD79A, TNFRSF1B
28cataract10.1
29esophagitis10.1
30linear iga disease10.1
31salpingitis10.1CD79A, TNFRSF1B
32crest syndrome10.1CD79A, TNFRSF1B
33spondylosis10.0CD79A, TNFRSF1B
34pemphigus vulgaris10.0
35entropion10.0
36large cell acanthoma10.0ITGB4, LAMA3, SERPINH1
37malignant histiocytosis10.0CD79A, COL17A1, DST
38early congenital syphilis10.0CD79A, TNFRSF1B
39blood group incompatibility10.0CD79A, COL17A1, DST
40diabetic macular edema10.0CD79A, COL17A1, DST
41lacrimal system cancer10.0CD79A, TNFRSF1B
42conjunctivitis10.0
43achilles bursitis9.9CD79A, TNFRSF1B
44sternum lymphoma9.9CD79A, TNFRSF1B
45keratitis9.9
46erythema multiforme9.9
47lymphoma9.9
48corneal ulcer9.9
49lupus erythematosus9.9
50mesangial proliferative glomerulonephritis9.9CD79A, CFP

Comorbidity relations with Cicatricial Pemphigoid via Phenotypic Disease Network (PDN):


Corneal Ulcer

Graphical network of the top 20 diseases related to Cicatricial Pemphigoid:



Diseases related to cicatricial pemphigoid

Symptoms & Phenotypes for Cicatricial Pemphigoid

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UMLS symptoms related to Cicatricial Pemphigoid:


exanthema, discharge from eye, coma blister

GenomeRNAi Phenotypes related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00327-A9.1CD79A, DST, SERPINH1

MGI Mouse Phenotypes related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.7ITGB4, LAMA3, LAMC2, SERPINH1, TNFRSF1B
2MP:00053818.6ITGB4, LAMA3, LAMC2, SERPINH1, TNFRSF1B

Drugs & Therapeutics for Cicatricial Pemphigoid

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Drugs for Cicatricial Pemphigoid (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Mycophenolic acidapprovedPhase 393924280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
2
Mycophenolate mofetilapproved, investigationalPhase 3939128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
3Immunosuppressive AgentsPhase 312770
4Antibiotics, AntitubercularPhase 36972
5Anti-Bacterial AgentsPhase 310884
6
rituximabapprovedPhase 1, Phase 21654174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
7
InfliximabapprovedPhase 1, Phase 2378170277-31-3
Synonyms:
 
Ig gamma-1 chain C region
Remicade
8
Riboflavinapproved, nutraceutical, vet_approvedPhase 1, Phase 216583-88-5493570
Synonyms:
(-)-Riboflavin
1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol
1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol
6,7-Dimethyl-9-D-ribitylisoalloxazine
6,7-Dimethyl-9-ribitylisoalloxazine
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-Benzo[g]pteridine-2,4(3H,10H)-dione
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine
7,8-Dimethyl-10-ribitylisoalloxazine
Beflavin
Beflavine
Benzo[g]pteridine riboflavin deriv.
E 101
E101
Flavaxin
Flavin BB
Flaxain
Food Yellow 15
 
Hyre
Lactobene
Lactoflavin
Lactoflavine
Ribipca
Ribocrisina
Riboderm
Riboflavina
Riboflavine
Riboflavinum
Ribosyn
Ribotone
Ribovel
Russupteridine yellow III
San Yellow B
Vitaflavine
Vitamin B2
Vitamin G
Vitasan B2
9
Folic Acidapproved, nutraceutical, vet_approvedPhase 1, Phase 2427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
10Antirheumatic AgentsPhase 1, Phase 210627
11Trace ElementsPhase 1, Phase 25802
12Vitamin B ComplexPhase 1, Phase 24229
13VitaminsPhase 1, Phase 25095
14Pharmaceutical SolutionsPhase 1, Phase 27793
15Dermatologic AgentsPhase 1, Phase 25674
16MicronutrientsPhase 1, Phase 25802
17Photosensitizing AgentsPhase 1, Phase 2476
18Gastrointestinal AgentsPhase 1, Phase 28109
19FolateNutraceuticalPhase 1, Phase 24279
20Vitamin B9NutraceuticalPhase 1, Phase 24279
21Vitamin B2NutraceuticalPhase 1, Phase 2165
22ImmunoglobulinsPhase 16045
23AntibodiesPhase 16045
24Autoantibodies126

Interventional clinical trials:

(show all 12)
idNameStatusNCT IDPhase
1Pharmacokinetics Study of Mycophenolic Acid in Patients With an Autoimmune Bullous Dermatose, Pemphigus or Cicatricial Pemphigoid.Not yet recruitingNCT02993133Phase 3
2Clinical Trial Evaluating Rituximab in Ocular Cicatricial PemphigoidCompletedNCT00584935Phase 1, Phase 2
3Limbal Epithelial Stem Cell Transplantation: a Phase II Multicenter TrialRecruitingNCT02318485Phase 2
4Use of Cross-linked Donor Corneas as Carriers for the Boston KeratoprosthesisRecruitingNCT01582880Phase 1, Phase 2
5Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet TransplantationAvailableNCT02149732Phase 1, Phase 2
6Topical Infliximab in Autoimmune Eyes With KeratoprosthesisEnrolling by invitationNCT02126020Phase 1, Phase 2
7The Improvement of Limbal Epithelial Culture Technique by Using Collagenase to Isolate Limbal Stem CellsUnknown statusNCT02202642Phase 1
8Topical Infliximab for Sterile Corneal MeltNot yet recruitingNCT02987686Phase 1
9Subconjunctival IVIg (Gamunex-C) Injection for Corneal Neovascularization and Inflammatory ConditionsWithdrawnNCT02042027Phase 1
10Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort StudyCompletedNCT00116090
11Genetic Susceptibility and Influence of the Microbiomae in Bullous PemphigoidRecruitingNCT02874079
12Immune Responses to Antigens in Non-infectious Eye Inflammatory DiseasesEnrolling by invitationNCT00357071

Search NIH Clinical Center for Cicatricial Pemphigoid


Cochrane evidence based reviews: pemphigoid, benign mucous membrane

Genetic Tests for Cicatricial Pemphigoid

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Anatomical Context for Cicatricial Pemphigoid

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MalaCards organs/tissues related to Cicatricial Pemphigoid:

36
Skin, Eye, Testes, Lung, Neutrophil, T cells, Pancreas

FMA organs/tissues related to Cicatricial Pemphigoid:

17
Mucous membranes, Skin

Publications for Cicatricial Pemphigoid

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Articles related to Cicatricial Pemphigoid:

(show top 50)    (show all 431)
idTitleAuthorsYear
1
Clinical features and in vivo confocal microscopy assessment in 12 patients with ocular cicatricial pemphigoid. (27275431)
2016
2
Autoimmune bullous diseases with skin and eye involvement: Cicatricial pemphigoid, pemphigus vulgaris, and pemphigus paraneoplastica. (26903186)
2016
3
Update on ocular cicatricial pemphigoid and emerging treatments. (26708362)
2016
4
IgM ocular cicatricial pemphigoid: a unique insight into the immune system. (26632795)
2015
5
Esophageal Cicatricial Pemphigoid as an Isolated Involvement Treated with Mycophenolate Mofetil. (26557393)
2015
6
NGF Modulates trkANGFR/p75NTR in I+SMA-Expressing Conjunctival Fibroblasts from Human Ocular Cicatricial Pemphigoid (OCP). (26569118)
2015
7
Characteristics of patients with ocular cicatricial pemphigoid referred to major tertiary hospital. (25863854)
2015
8
Cicatricial pemphigoid vegetans in a Polish woman. (26147045)
2015
9
Remission of anti-epiligrin cicatricial pemphigoid after excision of cervical adenocarcinoma. (24766621)
2014
10
Low-dose pulsed intravenous cyclophosphamide for severe ocular cicatricial pemphigoid in elderly patients. (25014147)
2014
11
Neutrophil collagenase, gelatinase, and myeloperoxidase in tears of patients with stevens-johnson syndrome and ocular cicatricial pemphigoid. (23962653)
2014
12
Brunsting-perry type cicatricial pemphigoid with IgG autoantibodies to LAD-1. (24124894)
2013
13
Outcomes of cataract surgery in ocular cicatricial pemphigoid. (23941520)
2013
14
Polymicrobial and microsporidial keratitis in a patient using Boston scleral contact lens for Sjogren's syndrome and ocular cicatricial pemphigoid. (23123433)
2013
15
Hypopharyngeal presentation of cicatricial pemphigoid: videofluorographic and direct laryngoscopic findings. (23442384)
2013
16
Coexistence of ocular cicatricial pemphigoid with Stevens Johnson syndrome. (23826544)
2013
17
A case of cicatricial pemphigoid of the larynx successfully treated with plasmapheresis therapy. (24170474)
2013
18
Ocular cicatricial pemphigoid masquerading as chronic conjunctivitis: a case report. (23269857)
2012
19
Ocular and oral mucous membrane pemphigoid (cicatricial pemphigoid). (22137224)
2012
20
Profile of local interleukin expression in a cohort of ocular cicatricial pemphigoid patients. (23081979)
2012
21
The frequency of other autoimmune disorders in patients with ocular cicatricial pemphigoid. (21595864)
2012
22
Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda. (23118521)
2012
23
Membrane array analysis of tear proteins in ocular cicatricial pemphigoid. (21552176)
2011
24
Cicatricial pemphigoid of the scalp mimicking discoid lupus erythematosus. (21920254)
2011
25
Pentoxifylline (anti-tumor necrosis factor drug): effective adjuvant therapy in the control of ocular cicatricial pemphigoid. (21279976)
2011
26
Ocular cicatricial pemphigoid: a review of clinical features, immunopathology, differential diagnosis, and current management. (21958173)
2011
27
Peripheral ulcerative keratitis after cataract surgery in a patient with ocular cicatricial pemphigoid. (21822128)
2011
28
Cicatricial pemphigoid in accompany with rheumatoid arthritis: a case report. (21180281)
2010
29
Early onset childhood cicatricial pemphigoid: a case report and review of the literature. (20537062)
2010
30
Transscleral diode laser cyclophotocoagulation and ocular cicatricial pemphigoid. (20635815)
2010
31
A tooth for an eye: cicatricial pemphigoid and the osteo-odonto-keratoprosthesis. (20956670)
2010
32
Anterior lamellar excision and laissez-faire healing for aberrant lashes in ocular cicatricial pemphigoid. (19911023)
2010
33
Scleral lenses and ocular cicatricial pemphigoid. (20697280)
2010
34
Recalcitrant cicatricial pemphigoid treated with the anti-TNF-alpha agent etanercept. (20120429)
2010
35
Combination of rituximab and intravenous immunoglobulin for recalcitrant ocular cicatricial pemphigoid: a preliminary report. (20045562)
2010
36
Transnasal endoscopy in a patient with cicatricial pemphigoid. (20524762)
2010
37
Cyclophosphamide and amniotic membrane transplantation in the management of ocular disease in a case of antiepiligrin cicatricial pemphigoid. (19747320)
2009
38
Ocular cicatricial pemphigoid: the role of scleral lenses in disease management. (19770718)
2009
39
T-helper 17 lymphocytes in ocular cicatricial pemphigoid. (19641634)
2009
40
Multiple mucosal involvement in cicatricial pemphigoid. (20161882)
2009
41
Combination treatment of intravenous immunoglobulin and cultivated oral mucosal epithelial transplantation for ocular cicatricial pemphigoid. (21686527)
2009
42
Transscleral diode laser cyclophotocoagulation in a patient with ocular cicatricial pemphigoid. (19928727)
2009
43
Laser light may improve the symptoms of oral lesions of cicatricial pemphigoid: a case report. (19878031)
2009
44
Intravenous immunoglobulin therapy for refractory ocular cicatricial pemphigoid: case report. (18724167)
2008
45
Exacerbation of undiagnosed ocular cicatricial pemphigoid after repair of involutional entropion. (18356734)
2008
46
Two cases of anti-epiligrin cicatricial pemphigoid with and without associated malignancy. (18779887)
2008
47
Ocular cicatricial pemphigoid. (18762085)
2008
48
A quick and simple serum test to differentiate bullous pemphigoid, epidermolysis bullosa acquisita, and anti-epiligrin cicatricial pemphigoid. (18718187)
2008
49
Brunsting-Perry cicatricial pemphigoid associated with autoantibodies to the C-terminal domain of BP180. (18637895)
2008
50
Ocular manifestations in a case of childhood cicatricial pemphigoid. (18609489)
2008

Variations for Cicatricial Pemphigoid

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Expression for genes affiliated with Cicatricial Pemphigoid

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Search GEO for disease gene expression data for Cicatricial Pemphigoid.

Pathways for genes affiliated with Cicatricial Pemphigoid

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Pathways related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

(show all 12)
idSuper pathwaysScoreTop Affiliating Genes
19.7COL17A1, ITGB4
29.7ITGB4, LAMA3
39.6LAMA3, LAMC2
49.4LAMC2, TNFRSF1B
5
Show member pathways
9.2ITGB4, LAMA3, LAMC2
6
Show member pathways
9.2ITGB4, LAMA3, LAMC2
79.2ITGB4, LAMA3, LAMC2
8
Show member pathways
8.5COL17A1, DST, ITGB4, LAMA3, LAMC2
98.5COL17A1, DST, ITGB4, LAMA3, LAMC2
10
Show member pathways
8.4CD79A, COL17A1, ITGB4, LAMA3, LAMC2
11
Show member pathways
7.8COL17A1, DST, ITGB4, LAMA3, LAMC2, SERPINH1
12
Show member pathways
7.8COL17A1, DST, ITGB4, LAMA3, LAMC2, SERPINH1

GO Terms for genes affiliated with Cicatricial Pemphigoid

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Cellular components related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell leading edgeGO:003125210.4DST, ITGB4
2basement membraneGO:000560410.2COL17A1, DST, LAMA3
3hemidesmosomeGO:00300569.9COL17A1, DST, ITGB4
4endoplasmic reticulum lumenGO:00057889.5CFP, COL17A1, SERPINH1
5membrane raftGO:00451218.9CD79A, SERPINH1, TNFRSF1B
6extracellular regionGO:00055768.5CFP, COL17A1, LAMA3, LAMC2, TNFRSF1B

Biological processes related to Cicatricial Pemphigoid according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell motilityGO:004887010.3DST, ITGB4
2epidermis developmentGO:00085449.9COL17A1, LAMA3, LAMC2
3extracellular matrix organizationGO:00301989.4ITGB4, LAMA3, LAMC2
4cell adhesionGO:00071559.4DST, ITGB4, LAMA3, LAMC2
5hemidesmosome assemblyGO:00315818.8COL17A1, ITGB4, LAMA3, LAMC2

Sources for Cicatricial Pemphigoid

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet