MCID: CRR011
MIFTS: 14

Cirrhosis, Noncryptogenic malady

Summaries for Cirrhosis, Noncryptogenic

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47OMIM, 33MalaCards
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MalaCards: Cirrhosis, Noncryptogenic is related to pulmonary fibrosis and hepatoblastoma. An important gene associated with Cirrhosis, Noncryptogenic is KRT18 (keratin 18), and among its related pathways are Cytoskeletal Signaling and EGFR1 Signaling Pathway. The compounds griseofulvin and fitc have been mentioned in the context of this disorder.

Description from OMIM:47 215600

Aliases & Classifications for Cirrhosis, Noncryptogenic

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47OMIM
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Aliases & Descriptions:

cirrhosis, noncryptogenic 47


Related Diseases for Cirrhosis, Noncryptogenic

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Cirrhosis, Noncryptogenic:



Diseases related to cirrhosis, noncryptogenic

Clinical Features for Cirrhosis, Noncryptogenic

Sources:
47OMIM
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Clinical features from OMIM:

215600

Drugs & Therapeutics for Cirrhosis, Noncryptogenic

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Cirrhosis, Noncryptogenic

Drug clinical trials:

Search ClinicalTrials for Cirrhosis, Noncryptogenic

Search NIH Clinical Center for Cirrhosis, Noncryptogenic

Search CenterWatch for Cirrhosis, Noncryptogenic

Genetic Tests for Cirrhosis, Noncryptogenic

Anatomical Context for Cirrhosis, Noncryptogenic

Animal Models for Cirrhosis, Noncryptogenic or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Cirrhosis, Noncryptogenic

Genetic Variations for Cirrhosis, Noncryptogenic

Expression for genes affiliated with Cirrhosis, Noncryptogenic

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cirrhosis, Noncryptogenic

Search GEO for disease gene expression data for Cirrhosis, Noncryptogenic.

Pathways for genes affiliated with Cirrhosis, Noncryptogenic

Sources:
4Cell Signaling Technology, 38NCBI BioSystems Database, 12EMD Millipore
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Pathways related to Cirrhosis, Noncryptogenic according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1KRT8, KRT18
29.1KRT8, KRT18
39.1KRT8, KRT18

Compounds for genes affiliated with Cirrhosis, Noncryptogenic

Sources:
45Novoseek, 11DrugBank, 24HMDB, 50PharmGKB
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Compounds related to Cirrhosis, Noncryptogenic according to GeneCards/GeneDecks:

(show all 22)
idCompoundScoreTop Affiliating Genes
1griseofulvin45 1110.5KRT8, KRT18
2fitc459.5KRT8, KRT18
3diethyl dithiocarbamate459.5KRT18, KRT8
4hematoxylin459.5KRT8, KRT18
5n-acetylglucosamine459.5KRT8, KRT18
6urea45 11 2411.4KRT18, KRT8
7gold459.4KRT8, KRT18
8bromodeoxyuridine459.4KRT8, KRT18
9sucrose45 11 2411.4KRT18, KRT8
10agar459.4KRT8, KRT18
11retinoid459.4KRT8, KRT18
12matrigel459.4KRT18, KRT8
13butyrate459.4KRT8, KRT18
14ethanol45 50 11 2412.3KRT8, KRT18
15doxorubicin45 50 1111.3KRT18, KRT8
16glycogen45 2410.3KRT8, KRT18
17actinomycin d459.2KRT18, KRT8
18paraffin459.2KRT8, KRT18
19forskolin45 50 1111.1KRT8, KRT18
20creatinine459.1KRT8, KRT18
21iron45 2410.0KRT18, KRT8
22lactate458.8KRT8, KRT18

GO Terms for genes affiliated with Cirrhosis, Noncryptogenic

Sources:
16Gene Ontology
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Cellular components related to Cirrhosis, Noncryptogenic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058829.1KRT8, KRT18
2keratin filamentGO:0450958.8KRT8, KRT18

Biological processes related to Cirrhosis, Noncryptogenic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1modulation by virus of host morphology or physiologyGO:0190489.1KRT8, KRT18
2tumor necrosis factor-mediated signaling pathwayGO:0332098.8KRT8, KRT18

Molecular functions related to Cirrhosis, Noncryptogenic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural molecule activityGO:0051989.1KRT8, KRT18
2scaffold protein bindingGO:0971108.8KRT8, KRT18

Products for genes affiliated with Cirrhosis, Noncryptogenic

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cirrhosis, Noncryptogenic

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet