MCID: CLR017
MIFTS: 50

Clear Cell Sarcoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Clear Cell Sarcoma

MalaCards integrated aliases for Clear Cell Sarcoma:

Name: Clear Cell Sarcoma 12 14
Sarcoma, Clear Cell 41 69
Adult Soft Part Clear Cell Sarcoma 12
Malignant Melanoma of Soft Tissues 12
Melanoma, Malignant, of Soft Parts 12
Clear Cell Sarcoma of Soft Parts 12
Malignant Melanoma of Soft Parts 12
Sarcoma Clear Cell 51

Classifications:



External Ids:

Disease Ontology 12 DOID:4233
MeSH 41 D018227
NCIt 46 C27370 C3745

Summaries for Clear Cell Sarcoma

Disease Ontology : 12 A sarcoma that is characterized by solid nests and fascicles of tumor cells with clear cytoplasm and prominent nucleoli. It presents as a slow growing mass that especially affects tendons and aponeuroses and it is deeply situated.

MalaCards based summary : Clear Cell Sarcoma, also known as sarcoma, clear cell, is related to kidney clear cell sarcoma and melanoma of soft tissue. An important gene associated with Clear Cell Sarcoma is ATF1 (Activating Transcription Factor 1), and among its related pathways/superpathways are Tyrosine Kinases / Adaptors and ErbB1 downstream signaling. The drugs Carboplatin and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include kidney, bone and lung, and related phenotypes are cellular and embryo

Wikipedia : 72 Clear-cell sarcoma (formerly known as malignant melanoma of the soft parts) is a rare form of cancer... more...

Related Diseases for Clear Cell Sarcoma

Diseases in the Small Cell Sarcoma family:

Clear Cell Sarcoma

Diseases related to Clear Cell Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 138)
# Related Disease Score Top Affiliating Genes
1 kidney clear cell sarcoma 34.0 BCOR WT1 YWHAE
2 melanoma of soft tissue 33.1 ATF1 CREB1 EWSR1
3 melanoma 30.6 ATF1 EWSR1 KIT MITF S100B
4 sarcomatosis 30.3 ATF1 WT1
5 malignant spindle cell melanoma 30.1 KIT MITF
6 myxoid liposarcoma 29.8 ATF1 EWSR1 FUS
7 small intestinal sarcoma 29.8 IGF2 KIT
8 rhabdomyosarcoma 29.5 ENO2 EWSR1 IGF2
9 hereditary wilms' tumor 29.4 IGF2 WT1
10 congenital mesoblastic nephroma 29.3 IGF2 KIT WT1
11 neuroblastoma 29.2 CREB1 ENO2 IGF2 KIT
12 ewing sarcoma 27.1 ATF1 BCOR ENO2 EWSR1 FUS IGF2
13 sarcoma 11.0
14 wilms tumor 1 11.0
15 conventional central osteosarcoma 10.5 BCOR EWSR1
16 lentigo maligna melanoma 10.5 MITF S100B
17 intracranial cysts 10.5 ENO2 S100B
18 bednar tumor 10.5 ENO2 S100B
19 orbital cancer 10.5 ENO2 EWSR1
20 askin's tumor 10.5 ENO2 EWSR1
21 epithelioid malignant peripheral nerve sheath tumor 10.5 ENO2 S100B
22 middle cerebral artery infarction 10.5 ENO2 S100B
23 ossifying fibromyxoid tumor 10.5 ENO2 S100B
24 head injury 10.4 ENO2 S100B
25 myxoid leiomyosarcoma 10.4 BCOR YWHAE
26 reticular perineurioma 10.4 KIT S100B
27 pineocytoma 10.4 ENO2 S100B
28 mixed type thymoma 10.4 KIT S100B
29 aggressive digital papillary adenocarcinoma 10.4 KIT S100B
30 papillary ependymoma 10.4 ENO2 S100B
31 breast angiosarcoma 10.4 KIT MITF
32 amelanotic melanoma 10.3 KIT S100B
33 endometrial stromal nodule 10.3 BCOR YWHAE
34 vulvar melanoma 10.3 ATF1 KIT
35 plexiform schwannoma 10.3 ENO2 KIT
36 conventional fibrosarcoma 10.3 ENO2 KIT
37 endometrial small cell carcinoma 10.3 ENO2 KIT
38 rete testis adenocarcinoma 10.3 ENO2 KIT
39 mesenchymal cell neoplasm 10.3 EWSR1 KIT
40 myxofibrosarcoma 10.3 FUS S100B
41 angiomyoma 10.3 ENO2 KIT
42 subependymal giant cell astrocytoma 10.3 ENO2 S100B
43 perineurioma 10.3 KIT S100B
44 juxtacortical chondroma 10.3 EWSR1 FUS
45 small cell neuroendocrine carcinoma 10.3 ENO2 KIT
46 olfactory neuroblastoma 10.3 ENO2 EWSR1 S100B
47 small cell osteogenic sarcoma 10.3 BCOR ENO2 EWSR1
48 extraosseous ewing's sarcoma 10.3 ENO2 EWSR1 S100B
49 testicular gonadoblastoma 10.3 KIT WT1
50 mucosal melanoma 10.3 KIT MITF

Graphical network of the top 20 diseases related to Clear Cell Sarcoma:



Diseases related to Clear Cell Sarcoma

Symptoms & Phenotypes for Clear Cell Sarcoma

MGI Mouse Phenotypes related to Clear Cell Sarcoma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.91 YWHAE BCOR CREB1 ENO2 ERBB3 IGF2
2 embryo MP:0005380 9.7 BCOR CREB1 ERBB3 IGF2 KIT MITF
3 muscle MP:0005369 9.43 YWHAE CREB1 ERBB3 IGF2 KIT WT1
4 respiratory system MP:0005388 9.1 CREB1 ENO2 ERBB3 IGF2 KIT WT1

Drugs & Therapeutics for Clear Cell Sarcoma

Drugs for Clear Cell Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 112)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 38904 498142
2
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
3
Dactinomycin Approved, Investigational Phase 3,Phase 2 50-76-0 457193 2019
4
Doxorubicin Approved, Investigational Phase 3,Phase 2 23214-92-8 31703
5
Etoposide Approved Phase 3,Phase 2,Phase 1 33419-42-0 36462
6
Vincristine Approved, Investigational Phase 3,Phase 2 2068-78-2, 57-22-7 5978
7
Lenograstim Approved, Investigational Phase 3,Phase 2,Phase 1 135968-09-1
8
Sulfamethoxazole Approved Phase 3 723-46-6 5329
9
Trimethoprim Approved, Vet_approved Phase 3 738-70-5 5578
10
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
11
Methylphenidate Approved, Investigational Phase 3 20748-11-2, 113-45-1 4158
12
Morphine Approved, Investigational Phase 3 57-27-2 5288826
13
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
14
Mechlorethamine Approved, Investigational Phase 3,Phase 2,Phase 1 51-75-2 4033
15
Cyproheptadine Approved Phase 3 129-03-3 2913
16
Histamine Approved, Investigational Phase 3 51-45-6, 75614-87-8 774
17
Doxil Approved June 1999 Phase 3,Phase 2 31703
18 Pancreatic Polypeptide Investigational Phase 3 59763-91-6
19 Alkylating Agents Phase 3,Phase 2,Phase 1
20 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
21 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
22 Anti-Infective Agents Phase 3,Phase 2,Phase 1
23 Antimitotic Agents Phase 3,Phase 2,Phase 1
24 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
25 Antirheumatic Agents Phase 3,Phase 2,Phase 1
26 Etoposide phosphate Phase 3,Phase 2,Phase 1
27 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
28 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
29 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
30 Adjuvants, Immunologic Phase 3,Phase 2,Phase 1
31 Liver Extracts Phase 3,Phase 1,Phase 2
32 Adjuvants, Anesthesia Phase 3
33 Analgesics Phase 3
34 Analgesics, Opioid Phase 3
35 Anesthetics Phase 3
36 Anesthetics, General Phase 3
37 Anesthetics, Intravenous Phase 3
38 Central Nervous System Depressants Phase 3
39 Narcotics Phase 3
40 Peripheral Nervous System Agents Phase 3
41 Epoetin alfa Phase 3 113427-24-0
42 Isophosphamide mustard Phase 3,Phase 2,Phase 1 0
43 Anti-Allergic Agents Phase 3
44 Antipruritics Phase 3
45 Dermatologic Agents Phase 3
46 Gastrointestinal Agents Phase 3
47 Histamine Antagonists Phase 3
48 Histamine H1 Antagonists Phase 3
49
Histamine Phosphate Phase 3 51-74-1 65513
50 Neurotransmitter Agents Phase 3

Interventional clinical trials:

(show all 35)

# Name Status NCT ID Phase Drugs
1 Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney Tumors Completed NCT00002610 Phase 3 carboplatin;cyclophosphamide;doxorubicin hydrochloride;etoposide;vincristine sulfate
2 Combination Chemotherapy Alone or With Radiation Therapy in Treating Children With Kidney Cancer Completed NCT00002611 Phase 3 cyclophosphamide;doxorubicin hydrochloride;etoposide;vincristine sulfate
3 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
4 E-MOSAIC Electronic Tool to Monitor Symptoms Completed NCT00477919 Phase 3
5 Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma Completed NCT00002764 Phase 3 doxorubicin hydrochloride;ifosfamide
6 Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00002641 Phase 3 doxorubicin hydrochloride;ifosfamide;isolated perfusion
7 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Recruiting NCT02180867 Phase 2, Phase 3 Doxorubicin Hydrochloride;Ifosfamide;Pazopanib Hydrochloride
8 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
9 Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplant in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the Kidney Unknown status NCT00025103 Phase 2 carboplatin;cyclophosphamide;doxorubicin hydrochloride;etoposide;melphalan;vincristine sulfate
10 Phase 2 Study in Patients With MiT Tumors Completed NCT00557609 Phase 2 ARQ 197
11 A Study of R1507 in Participants With Recurrent or Refractory Sarcoma Completed NCT00642941 Phase 2 RG1507
12 Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors Completed NCT00335556 Phase 2 Doxorubicin Hydrochloride;Irinotecan Hydrochloride;Cyclophosphamide;Etoposide;Carboplatin;Vincristine Sulfate
13 Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery Completed NCT01553539 Phase 2 therapeutic angiotensin-(1-7)
14 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2 Gamma-Secretase Inhibitor RO4929097;Vismodegib
15 Chemotherapy in Treating Patients With Solid Tumors Completed NCT00003103 Phase 1, Phase 2 docetaxel
16 High-dose ICE With Amifostine Completed NCT00003657 Phase 2 Amifostine;Carboplatin;Etoposide;Ifosfamide
17 Second Line ColoRectal Cancer Therapy in Combination With Combination of FOL- Folinic Acid(Leucovorin), F - Fluorouracil and OX - Oxaliplatin (FOLFOX) Completed NCT00278889 Phase 2 AZD2171;5-fluorouracil;Leucovorin;Oxaliplatin;Bevacizumab
18 QUILT-3.031: AMG 337 in Subjects With Advanced or Metastatic Clear Cell Sarcoma Recruiting NCT03132155 Phase 2 AMG 337
19 Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors Recruiting NCT02867592 Phase 2 Cabozantinib S-malate
20 CREATE: Cross-tumoral Phase 2 With Crizotinib Active, not recruiting NCT01524926 Phase 2 Crizotinib (PF-02341066)
21 Sunitinib Malate With or Without Gemcitabine Hydrochloride in Treating Patients With Advanced Kidney Cancer That Cannot Be Removed By Surgery Active, not recruiting NCT01164228 Phase 2 gemcitabine hydrochloride;sunitinib malate
22 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
23 Dalteparin and Sunitinib Malate as First-Line Therapy in Treating Patients With Kidney Cancer That is Metastatic or Cannot Be Removed by Surgery Completed NCT01061411 Phase 1 Dalteparin;Sunitinib Malate
24 Thalidomide and Docetaxel in Treating Patients With Advanced Cancer Completed NCT00049296 Phase 1 docetaxel;thalidomide
25 Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors Recruiting NCT02390843 Phase 1 Simvastatin;Cyclophosphamide;Topotecan;Myeloid growth factor
26 Vaccine Trial for Clear Cell Sarcoma, Pediatric Renal Cell Carcinoma, Alveolar Soft Part Sarcoma and Children With Stage IV Melanoma Active, not recruiting NCT00258687 Phase 1
27 Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors Active, not recruiting NCT01331135 Phase 1 sirolimus
28 Study of Information Received About Fertility and Infertility in Patients Who Have Finished Treatment for Cancer Unknown status NCT01295463
29 Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom Unknown status NCT00757614
30 Biomarkers in Tissue Samples From Patients With High-Risk Wilms Tumor Completed NCT01118078
31 Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer Patients Completed NCT00253383
32 Molecular-Guided Therapy for Childhood Cancer Recruiting NCT02162732
33 Study of Kidney Tumors in Younger Patients Recruiting NCT00898365
34 Studying Biomarkers in Samples From Younger Patients With Kidney Cancer Withdrawn NCT01642095
35 Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Refractory Solid Tumors Withdrawn NCT00499291 paclitaxel albumin-stabilized nanoparticle formulation

Search NIH Clinical Center for Clear Cell Sarcoma

Cochrane evidence based reviews: sarcoma, clear cell

Genetic Tests for Clear Cell Sarcoma

Anatomical Context for Clear Cell Sarcoma

MalaCards organs/tissues related to Clear Cell Sarcoma:

38
Kidney, Bone, Lung, Liver, Lymph Node, Myeloid, Tongue

Publications for Clear Cell Sarcoma

Articles related to Clear Cell Sarcoma:

(show top 50) (show all 459)
# Title Authors Year
1
Dysregulated mitogen-activated protein kinase signalling as an oncogenic basis for clear cell sarcoma of the kidney. ( 29243812 )
2018
2
Cutaneous Melanocytoma With CRTC1-TRIM11 Fusion: Report of 5 Cases Resembling Clear Cell Sarcoma. ( 29240581 )
2018
3
Establishment and proteomic characterization of patient-derived clear cell sarcoma xenografts and cell lines. ( 29197033 )
2018
4
Clear Cell Sarcoma of the Tongue on MRI and PET/CT. ( 29401145 )
2018
5
Bladder Recurrence of Clear Cell Sarcoma of the Kidney Seven Years After Initial Presentation. ( 28438624 )
2017
6
Clear cell sarcoma-like tumor of the gastrointestinal tract: A clinicopathological review. ( 28887884 )
2017
7
Imprint cytology of clear cell sarcoma-like tumor of the gastrointestinal tract in the small intestine: A case report. ( 28695686 )
2017
8
Primary Renal Sarcomas With BCOR-CCNB3 Gene Fusion: A Report of 2 Cases Showing Histologic Overlap With Clear Cell Sarcoma of Kidney, Suggesting Further Link Between BCOR-related Sarcomas of the Kidney and Soft Tissues. ( 28817404 )
2017
9
Complete response of mediastinal clear cell sarcoma to pembrolizumab with radiotherapy. ( 28725344 )
2017
10
A case of clear cell sarcoma-A rare malignancy. ( 28587971 )
2017
11
Clear cell sarcoma of kidney involving a horseshoe kidney and harboring EGFR internal tandem duplication. ( 28440018 )
2017
12
Primary mediastinal clear cell sarcoma: a case report and review of the literature. ( 28086809 )
2017
13
Subcutaneous pigmented clear cell sarcoma as a challenging simulator of melanoma. ( 28815555 )
2017
14
Malignant melanocytic neoplasm of pancreas with liver metastasis: Is it malignant melanoma or clear cell sarcoma? ( 28195103 )
2017
15
Diagnostic utility of cyclin D1 in the diagnosis of small round blue cell tumors in children and adolescents: beware of cyclin D1 expression in clear cell sarcoma of the kidney and CIC-DUX4 fusion-positive sarcomas. Comment on Magro et al (2016). ( 28499544 )
2017
16
Diagnostic utility of cyclin D1 in the diagnosis of small round blue cell tumors in children and adolescents: beware of cyclin D1 expression in clear cell sarcoma of the kidney and CIC-DUX4 fusion-positive sarcomas. Comment on Magro et al (2016)-reply. ( 28499546 )
2017
17
Clear cell sarcoma of the scalp: A case report. ( 28791725 )
2017
18
Concurrent occurrence of neuroblastoma and clear cell sarcoma of kidney in an infant: Is it a random event? ( 28195107 )
2017
19
Primary Clear Cell Sarcoma of the Dermis Mimicking Malignant Melanoma. ( 29072181 )
2017
20
Brain metastasis from gastrointestinal clear cell sarcoma. ( 27719746 )
2017
21
Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma. ( 28745431 )
2017
22
Dual tumor - Clear cell sarcoma of kidney with differentiating neuroblastoma: A rare case with review of literature. ( 28195106 )
2017
23
Renal Clear Cell Sarcoma - Anaplastic Variant: A Rare Entity. ( 28273978 )
2017
24
Clear cell sarcoma with intraepidermal nests requiring the differential diagnosis of malignant melanoma. ( 28256744 )
2017
25
Activity and safety of crizotinib in patients with advanced clear cell sarcoma with MET alterations. European Organization for Research and Treatment of Cancer phase 2 trial 90101 "CREATE". ( 28950372 )
2017
26
FNAC aided diagnosis of clear cell sarcoma of kidney: Report of two cases in infants. ( 28421721 )
2017
27
Mutually exclusive BCOR internal tandem duplications and YWHAE-NUTM2 fusions in clear cell sarcoma of kidney: not the full story. ( 27000436 )
2016
28
Clear cell sarcoma of the paraspinal ligament - A rare tumor at an unusual location: A review. ( 27381137 )
2016
29
Gastrointestinal clear cell sarcoma-like tumour of the ascending colon. ( 26890846 )
2016
30
Clear cell sarcoma of vulva. A case report. ( 27869448 )
2016
31
Aberrant epigenetic regulation in clear cell sarcoma of the kidney featuring distinct DNA hypermethylation and EZH2 overexpression. ( 26848979 )
2016
32
Recurrent BCOR Internal Tandem Duplication and YWHAE-NUTM2B Fusions in Soft Tissue Undifferentiated Round Cell Sarcoma of Infancy: Overlapping Genetic Features With Clear Cell Sarcoma of Kidney. ( 26945340 )
2016
33
Primary pulmonary clear cell sarcoma-the first two reported cases. ( 27112339 )
2016
34
Whole-exome sequencing identifies a somatic missense mutation of NBN in clear cell sarcoma of the salivary gland. ( 27109316 )
2016
35
BCOR internal tandem duplications in clear cell sarcoma of the kidney. ( 26874462 )
2016
36
Biology and management of clear cell sarcoma: state of the art and future perspectives. ( 27253849 )
2016
37
Intraperitoneal Rosai-Dorfman disease associated with clear cell sarcoma: first case report. ( 27814905 )
2016
38
A giant clear cell sarcoma on right scapular: A case report. ( 27452744 )
2016
39
Primary clear cell sarcoma of the head and neck: a case series with review of the literature. ( 27264732 )
2016
40
Revealing the role of VEGFA in clear cell sarcoma of the kidney by protein-protein interaction network and significant pathway analysis. ( 26893674 )
2016
41
Melan-A/MART-1 immunity in a EWS-ATF1 translocated clear cell sarcoma patient treated with sunitinib: a case report. ( 25880253 )
2015
42
Activation of human telomerase reverse transcriptase through gene fusion in clear cell sarcoma of the kidney. ( 25481751 )
2015
43
Boron neutron capture therapy (BNCT) as a new approach for clear cell sarcoma (CCS) treatment: Trial using a lung metastasis model of CCS. ( 26337135 )
2015
44
Whole transcriptome sequencing identifies BCOR internal tandem duplication as a common feature of clear cell sarcoma of the kidney. ( 26516930 )
2015
45
BCOR internal tandem duplication and YWHAE-NUTM2B/E fusion are mutually exclusive events in clear cell sarcoma of the kidney. ( 26493387 )
2015
46
Clear cell sarcoma of the penis: a case report. ( 26069887 )
2015
47
Visual Diagnosis: 8-year-old Male with a Skin Mass and Inguinal Lymphadenopathy. Clear Cell Sarcoma. ( 26232472 )
2015
48
TCF21 hypermethylation in genetically quiescent clear cell sarcoma of the kidney. ( 26158413 )
2015
49
Clear cell sarcoma-like tumor of the gastrointestinal tract: an evolving entity. ( 25724038 )
2015
50
Clear cell sarcoma of the pancreas: a case report and review of literature. ( 25973121 )
2015

Variations for Clear Cell Sarcoma

Expression for Clear Cell Sarcoma

Search GEO for disease gene expression data for Clear Cell Sarcoma.

Pathways for Clear Cell Sarcoma

GO Terms for Clear Cell Sarcoma

Biological processes related to Clear Cell Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.56 ATF1 BCOR CREB1 EWSR1 FUS IGF2
2 positive regulation of protein kinase B signaling GO:0051897 9.43 ERBB3 IGF2 KIT
3 melanocyte differentiation GO:0030318 9.16 KIT MITF
4 positive regulation of cardiac muscle tissue development GO:0055025 8.62 CREB1 ERBB3

Molecular functions related to Clear Cell Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.77 ATF1 BCOR CREB1 ENO2 ERBB3 EWSR1
2 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003705 9.33 ATF1 CREB1 MITF
3 identical protein binding GO:0042802 9.17 ATF1 CREB1 ERBB3 EWSR1 FUS S100B

Sources for Clear Cell Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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