Aliases & Classifications for Cleft Lip

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Aliases & Descriptions for Cleft Lip:

Name: Cleft Lip 11 50 39 13
Cleft Lip, Unilateral, Complete 11
Complete Unilateral Cleft Lip 11
 
Labium Leporinum 11
Cheiloschisis 11
Hare Lip 11

Classifications:



External Ids:

Disease Ontology11 DOID:9296
ICD1030 Q36, Q36.9
MeSH39 D002971
NCIt45 C87175

Summaries for Cleft Lip

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MalaCards based summary: Cleft Lip, also known as cleft lip, unilateral, complete, is related to orofacial cleft 6 and fibrous dysplasia. An important gene associated with Cleft Lip is CLPTM1 (CLPTM1, Transmembrane Protein), and among its related pathways are Defective MTR causes methylmalonic aciduria and homocystinuria type cblG and Angiogenesis (CST). Affiliated tissues include bone, heart and skin, and related mouse phenotypes are hearing/vestibular/ear and respiratory system.

Related Diseases for Cleft Lip

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Diseases related to Cleft Lip via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 310)
idRelated DiseaseScoreTop Affiliating Genes
1orofacial cleft 632.6IRF6, SATB2, TP63
2fibrous dysplasia29.6IRF6, MSX1, MTHFR, SATB2, TGFB3, TP63
3cleft lip/palate12.5
4cleft lip/palate-ectodermal dysplasia syndrome12.4
5cleft lip +/- cleft palate12.3
6ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 312.2
7coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or mental retardation12.2
8isolated cleft lip12.1
9cleft lip and alveolus12.1
10median cleft lip/mandibule12.0
11arthrogryposis, ectodermal dysplasia, cleft lip/palate, and developmental delay12.0
12orofacial cleft 1112.0
13hay-wells syndrome11.9
14cleft lip/palate with abnormal thumbs and microcephaly11.9
15ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome 111.9
16coloboma, cleft lip/palate and mental retardation syndrome11.9
17polydactyly cleft lip palate psychomotor retardation11.9
18van der woude syndrome11.9
19eec syndrome11.9
20cleft lip/palate with characteristic facies, intestinal malrotation, and lethal congenital heart disease11.9
21microcephaly, corpus callosum dysgenesis and cleft lip-palate11.9
22cleft lip, congenital healed11.9
23amelia cleft lip palate hydrocephalus iris coloboma11.8
24anophthalmia cleft lip palate hypothalamic disorder11.8
25cleft lip and palate malrotation cardiopathy11.8
26cleft lip and/or palate with mucous cysts of lower11.8
27cleft lip palate dysmorphism kumar type11.8
28cleft lip palate mental retardation corneal opacity11.8
29cleft lip palate oligodontia syndactyly pili torti11.8
30cleft lip palate pituitary deficiency11.8
31cleft lip palate-tetraphocomelia11.8
32craniosynostosis cleft lip palate arthrogryposis11.8
33holoprosencephaly ectrodactyly cleft lip palate11.8
34lagophthalmia cleft lip palate11.8
35microbrachycephaly ptosis cleft lip11.8
36multiple congenital anomalies mental retardation, growth failure and cleft lip palate11.8
37syndactyly ectodermal dysplasia cleft lip palate hand foot11.8
38tibial hemimelia cleft lip palate11.8
39cleft lip/palate-deafness-sacral lipoma syndrome11.8
40cleft lip-retinopathy syndrome11.8
41auriculoocular anomalies-cleft lip syndrome11.8
42auricular abnormalities-cleft lip with or without cleft palate-ocular abnormalities syndrome11.8
43rapp-hodgkin syndrome11.8
44roberts syndrome11.7
45hartsfield syndrome11.7
46popliteal pterygium syndrome 111.6
47orofacial cleft 511.6
48orofacial cleft 1011.6
49vici syndrome11.6
50blepharocheilodontic syndrome11.6

Graphical network of the top 20 diseases related to Cleft Lip:



Diseases related to cleft lip

Symptoms & Phenotypes for Cleft Lip

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MGI Mouse Phenotypes related to Cleft Lip according to GeneCards Suite gene sharing:

41 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.6BMP4, FGFR1, IRF6, MSX1, PAX9, RARA
2MP:00053889.5BMP4, MSX1, PAX9, RARA, SATB2, TGFB3
3MP:00107719.4BMP4, FGFR1, IRF6, MSX1, MTHFR, NECTIN1
4MP:00053699.4BMP4, FGFR1, MID1, MSX1, PAX9, RARA
5MP:00028739.3BMP4, FGFR1, MID1, PAX9, RARA, TBX10
6MP:00053808.9BMP4, FGFR1, IRF6, MID1, MSX1, PAX9
7MP:00053718.8BMP4, FGFR1, IRF6, MSX1, MTHFR, PAX9
8MP:00053818.7BMP4, FGFR1, IRF6, MSX1, PAX9, RARA
9MP:00053908.5BMP4, FGFR1, IRF6, MSX1, MTHFR, PAX9
10MP:00053828.5BMP4, FGFR1, IRF6, MSX1, NECTIN1, PAX9
11MP:00053918.2BMP4, FGFR1, MSX1, MTHFR, NECTIN1, RARA
12MP:00107687.8BMP4, FGFR1, IRF6, MID1, MSX1, MTHFR
13MP:00053787.7BMP4, FGFR1, IRF6, MID1, MSX1, MTHFR

Drugs & Therapeutics for Cleft Lip

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Drugs for Cleft Lip (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 82)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Propofolapproved, investigational, vet_approvedPhase 410822078-54-84943
Synonyms:
2, 6-Diisopropylphenol
2,6 Diisopropylphenol
2,6-Bis(1-methylethyl)phenol
2,6-Bis(Isopropyl)-phenol
2,6-DIISOPROPYLPHENOL
2,6-Diisopropyl phenol
2,6-Diisopropylphenol
2,6-bis(1-methylethyl)-phenol
2,6-di(propan-2-yl)phenol
2078-54-8
28449-97-0
4-06-00-03435 (Beilstein Handbook Reference)
50356-15-5
AB00513968
AC-2038
AC1L1J9Y
AC1Q1OUI
AI3-26295
AM-149
Abbott Brand of Propofol
Alpha Brand of Propofol
Ampofol
Aquafol
Astra Brand of Propofol
AstraZeneca Brand of Propofol
BIDD:GT0436
BPBio1_000950
BPBio1_000969
BRD-K82255054-001-03-5
BRN 1866484
BSPBio_000862
Biomol-NT_000248
Braun Brand of Propofol
C07523
C12H18O
CAS-2078-54-8
CCRIS 9000
CHEBI:44915
CHEMBL526
CID4943
CPD-11437
CPD000059151
Curamed Brand of Propofol
D00549
D015742
D0617
D126608
D126608_ALDRICH
DB00818
DDS-04F
Diisopropylphenol
Dipravan
Diprivan
Diprivan (TN)
Diprivan Injectable emulsion
Disoprivan
Disoprofol
EINECS 218-206-6
EU-0100437
Fresenius Brand of Propofol
Fresenius Kabi Brand of Propofol
Fresofol
HMS1570L04
HMS2089O21
HMS2094E17
 
HSDB 7123
ICI 35,868
ICI 35868
ICI-35,868
ICI-35868
ICI35,868
ICI35868
InChI=1/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H
Ivofol
Jsp004266
Juste Brand of Propofol
LS-996
Lopac-D126608
Lopac0_000437
MLS001066348
MLS001335999
MLS002454360
MolPort-001-794-517
NCGC00015389-01
NCGC00015389-02
NCGC00015389-04
NCGC00015389-09
NCGC00091538-01
NCGC00091538-02
NCGC00091538-03
NCGC00091538-04
NCGC00091538-05
NCGC00091538-06
NSC 5105
NSC5105
PFL
Parnell Brand of Propofol
Pisa Brand of Propofol
Prestwick0_000931
Prestwick1_000931
Prestwick2_000931
Prestwick3_000931
Propofol
Propofol (JAN/USAN/INN)
Propofol Abbott
Propofol Fresenius
Propofol IDD-D
Propofol MCT
Propofol Rovi
Propofol [USAN:INN:BAN]
Propofol(2,6-Diisopropylphenol)
Propofol-Lipuro
Propofolum
Propofolum [Latin]
Rapinovet
Recofol
Rovi Brand of Propofol
S01-0189
SAM002264610
SMR000059151
SPBio_003031
SPECTRUM1505022
ST50405911
Schering Brand of Propofol
UNII-YI7VU623SF
W505102_ALDRICH
ZD-0859
ZINC00968303
Zeneca Brand of Propofol
ghl.PD_Mitscher_leg0.558
nchembio.552-comp7
propofol
2
Sevofluraneapproved, vet_approvedPhase 450828523-86-65206
Synonyms:
1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane
28523-86-6
AC-15484
AC1L1JU0
BRN 2041023
Bax 3084
C009250
C07520
C4H3F7O
CHEBI:9130
CHEMBL1200694
CID5206
D00547
DB01236
F0691
Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl Ether
Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
I14-13357
LS-67851
MR6S4
 
MR_6S4
MolPort-001-775-746
NCGC00167421-01
PC4681
Sevofluran
Sevoflurane
Sevoflurane (JAN/USAN/INN)
Sevoflurane [USAN:INN:BAN:JAN]
Sevoflurano
Sevoflurano [INN-Spanish]
Sevofluranum
Sevofluranum [INN-Latin]
Sevofrane
Sevorane
Sojourn
UNII-38LVP0K73A
Ultane
Ultane (TN)
ZINC01530810
fluoromethyl hexafluoroisopropyl ether
fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
sevoflurane
3
Amoxicillinapproved, vet_approvedPhase 446526787-78-033613, 2171
Synonyms:
(-)-6-(2-Amino-2-(P-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo-(3.2.0)heptane-2-carboxylic acid
(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
26787-78-0
33911-69-2
34642-77-8 (mono-hydrochloride salt)
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-(p-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-, D- (8CI)
6-(D-(-)-alpha-Amino-p-hydroxyphenylacetamido)penicillanic acid
6-(D-(-)-p-Hydroxy-alpha-aminobenzyl)penicillin
6-(a-Amino-4-hydroxyphenylacetamido)penicillanic acid
6-(p-Hydroxy-alpha-aminophenylacetamido)penicillanic acid
6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid
6-[[Amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 9CI
61336-70-7 (TRIHYDRATE)
6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carbonyl
6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid
71447-36-4
81030-75-3
AC-12263
AC1L1PY2
AMC
AMOXICILLIN CRYSTALLINE
AMOXICILLIN PEDIATRIC
AMPC
AUGMENTIN '125'
AUGMENTIN '200'
AUGMENTIN '250'
AUGMENTIN '400'
AUGMENTIN '500'
AUGMENTIN '875'
AUGMENTIN ES-600
AX
Actimoxi
Almodan
Ambap26787-78-0
Amix
Amoclen
Amolin
Amopen
Amopenixin
Amoram
Amox
Amox 250 Cap 250mg
Amox 500 Cap 500mg
Amox S 125 Sus 125mg/5ml
Amox S 250 Sus 250mg/5ml
Amoxi
Amoxi-Mast
Amoxi-mast
Amoxibiotic
Amoxicaps
Amoxicilina
Amoxicilina [INN-Spanish]
Amoxicillin (INN)
Amoxicillin (TN)
Amoxicillin (anhydrous)
Amoxicillin (inn)
Amoxicillin Trihydrate
Amoxicillin and clavulanate potassium
Amoxicillin anhydrous
Amoxicillin pediatric
Amoxicillin trihydrate
Amoxicillin(usan)
Amoxicilline
Amoxicilline [INN-French]
Amoxicilline [INN]
Amoxicilline [inn]
Amoxicillinum
Amoxicillinum [INN-Latin]
Amoxid
Amoxiden
Amoxil
Amoxivet
Amoxycillin
Amoxycillin Trihydrate
Amoxycillin trihydrate
Amoxycillin, BAN
Amoxymed
Amrit
Anemolin
Apo-Amoxi
Apo-Amoxi Cap 250mg
Apo-Amoxi Cap 500mg
Apo-Amoxi Pwr for Susp 125mg/5ml
Apo-Amoxi Pwr for Susp 250mg/5ml
Apo-amoxi
Apo-amoxi sugar free
Aspenil
BL-P 1410
BLP 1410
BPBio1_000499
BRD-K55044200-001-03-9
BRL 2333
BRL-2333
BSPBio_000453
 
Biomox
Bristamox
C06827
CHEBI:2676
CHEBI:53712
CHEMBL1082
CID33613
CPD000058707
Cemoxin
Clamoxyl
Clamoxyl (SKB)
D-(-)-alpha-Amino-p-hydroxybenzyl penicillin
D-(-)-alpha-Amino-p-hydroxybenzylpenicillin
D-(alpha-Amino-p-hydroxybenzyl)penicillin
D-2-Amino-2-(4-hydroxyphenyl)acetamidopenicillanic acid
D-Amoxicillin
D07452
DB01060
Delacillin
DisperMox
Dispermox
EINECS 248-003-8
Efpenix
Flemoxin
Galenamox
Gen-Amoxicillin 250mg
Gen-Amoxicillin 500mg
HMS1569G15
HSDB 3204
Hiconcil
Histocillin
Hydroxyampicillin
Ibiamox
Imacillin
LS-149721
Lamoxy
Larotid
MLS000028632
MLS002222248
Metafarma capsules
Metifarma capsules
MolPort-003-981-182
MolPort-005-933-687
Moxacin
Moxal
Moxatag
NCGC00179554-01
NSC 277174
NSC277174
Novamoxin Cap 250mg
Novamoxin Cap 500mg
Novamoxin Sus 125mg/5ml
Novamoxin Sus 250mg/5ml
Nu-Amoxi Cap 250mg
Nu-Amoxi Cap 500mg
Nu-Amoxi Sus 125/5ml
Nu-Amoxi Sus 250mg/5ml
Ospamox
P-Hydroxyampicillin
PHL-amoxicillin
PMS-amoxicillin
Pamoxicillin
Piramox
Polymox
Prestwick0_000357
Prestwick1_000357
Prestwick2_000357
Prestwick3_000357
Prestwick_713
Prevpac
Pro Amox Pwr for Oral Susp 125mg/5ml
Pro Amox-250 Cap 250mg
Pro Amox-500 Cap 500mg
Pro-Amox-250 Orl Sus 250mg/5ml
R-Hydroxyampicillin
Rimoxallin
Ro 10-8756
Robamox
SAM002264592
SMR000058707
SPBio_002374
Sauracillin
Sawamox PM
Sumox
Tolodina
Trimox
Unicillin
Utimox
Vetramox
Wymox
Zimox
alpha-Amino-p-hydroxybenzylpenicillin
amoxicillanyl
amoxicillin
p-Hydroxyampicillin
α-amino-p-hydroxybenzylpenicillin
4Anti-Infective AgentsPhase 4, Phase 2, Phase 122062
5Central Nervous System DepressantsPhase 4, Phase 2, Phase 313403
6Anesthetics, GeneralPhase 4, Phase 2, Phase 32934
7Anesthetics, IntravenousPhase 4, Phase 2, Phase 32538
8Antibiotics, AntitubercularPhase 4, Phase 17180
9AnestheticsPhase 4, Phase 2, Phase 39596
10Anti-Bacterial AgentsPhase 4, Phase 111226
11Anesthetics, InhalationPhase 4684
12Antitubercular AgentsPhase 41343
13Platelet Aggregation InhibitorsPhase 42516
14Hypnotics and SedativesPhase 42616
15
AcetylcholineapprovedPhase 3, Phase 1, Phase 280551-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
16
Ketamineapproved, vet_approvedPhase 2, Phase 35696740-88-13821
Synonyms:
(+-)-Ketamine
(+/-)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
(+/-)-2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
(+/-)-Ketamine
(-)-Ketamine
(S)-(-)-Ketamine
(S)-Ketamine
(±)-ketamine
100477-72-3
2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone
2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one
2-(Methylamino)-2-(2-chlorophenyl)cyclohexanone
2-(methylamino)-2-(2-chlorophenyl)cyclohexanone
2-(o-Chlorophenyl)-2-(methylamino)-cyclohexanone
2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
2-(o-chlorophenyl)-2-(methylamino)-cyclohexanone
33643-45-7
6740-88-1
79499-51-7
AC1L1GSH
AC1Q40UR
AKOS001053247
BRN 2216965
C07525
C13H16ClNO
CHEBI:138833
CHEBI:6121
CHEMBL742
CI 581 base
CI-581
CID3821
CLSTA 20
Calypsol
Cetamina
Cetamina [INN-Spanish]
Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)- (9CI)
Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)- (9CI)
Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, (+/-)- (8CI)
D08098
DB01221
 
DEA No. 7285
DL-ketamine
DivK1c_000217
EINECS 229-804-1
Esketamine
Green
IDI1_000217
KBio1_000217
KETAMINE HCL
Ketaject
Ketalar
Ketalar base
Ketamina
Ketamine (INN)
Ketamine Base
Ketamine HCL
Ketamine [INN:BAN]
Ketaminum
Ketaminum [INN-Latin]
Ketanest
Ketoject
Ketolar
Kétamine
L-Ketamine
LS-57301
MLS001331674
MolPort-001-838-070
NCGC00159480-02
NCGC00159480-03
NINDS_000217
NMDA
NSC 70151
NSC70151
SMR000238141
Special K
Special K [street name]
T385
Tekam
Tekam (TN)
UNII-690G0D6V8H
dl-Ketamine
ketamine
l-Ketamine
17
Fentanylapproved, illicit, investigational, vet_approvedPhase 3821437-38-73345
Synonyms:
1-Phenethyl-4-(N-phenylpropionamido)piperidine
1-Phenethyl-4-N-propionylanilinopiperidine
1-phenethyl-4-N-propionylanilinopiperidine
437-38-7
5-22-08-00049 (Beilstein Handbook Reference)
80832-90-2
990-73-8 (citrate)
AC1L1FQ2
Actiq
BIDD:GT0555
BRN 0494484
CHEBI:119915
CHEMBL596
CID3345
D00320
DB00813
Duragesic
Duragesic (TN)
Duragesic-100
Duragesic-12
Duragesic-25
Duragesic-50
Duragesic-75
Durogesic
EINECS 207-113-6
Fentanest
Fentanil
Fentanil [DCIT]
Fentanila
Fentanila [INN-Spanish]
Fentanilo
Fentanyl
Fentanyl (JAN/USAN/INN)
Fentanyl CII
Fentanyl [INN:BAN]
Fentanyl citrate
Fentanyl-100
Fentanyl-12
Fentanyl-25
 
Fentanyl-50
Fentanyl-75
Fentanylum
Fentanylum [INN-Latin]
HSDB 3329
IONSYS
JNS020QD
L001275
LS-124439
Matrifen
MolPort-003-847-369
N-(1-Phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-Phenethyl-4-piperidyl)propionanilide
N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide
N-(1-Phenethylpiperidin-4-yl)-N-phenylpropionamide
N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-phenethyl-4-piperidyl)propionanilide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropanamide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide
N-Phenethyl-4-(N-propionylanilino)piperidine
N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenethyl-4-(N-propionylanilino)piperidine
N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
NCGC00168252-01
Nasalfent
Oprea1_152073
Oprea1_207148
PDSP1_000860
PDSP2_000846
Pentanyl
Phentanyl
Propanamide, N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)- (9CI)
R 4263
Rapinyl
Sentonil
Sublimase
Sublimaze
UNII-UF599785JZ
fentanyl
18
Bupivacaineapproved, investigationalPhase 2, Phase 312332180-92-9, 38396-39-32474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
(±)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
 
DepoBupivacaine
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
racemic bupivacaine
19
LevobupivacaineapprovedPhase 2, Phase 317227262-47-192253
Synonyms:
(-)-Bupivacaine
(-)-bupivacaine
(2S)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(S)-1-Butyl-2',6'-pipecoloxylidide
(S)-Bupivacaine
(S)-bupivacaine
27262-47-1
27262-48-2
AC1L3NQM
BIDD:GT0471
C07887
C18H28N2O
CAS-18010-40-7
CHEBI:6149
CID92253
D08116
 
DB01002
L(-)-Bupivacaine
L-(-)-1-Butyl-2',6'-pipecoloxylidide
L-(-)-Bupivacaine
L-(-)-bupivacaine
LS-109843
LS-187025
LS-187789
Levobupivacaine
Levobupivacaine (INN)
Levobupivacaine [INN:BAN]
Levobupivacaine hydrochloride
MolPort-004-959-713
NCGC00016733-01
NCGC00159482-02
Novabupi
Novabupi (TN)
20
Folic Acidapproved, nutraceutical, vet_approvedPhase 3439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
21
leucovorinapproved, NutraceuticalPhase 3323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
22abobotulinumtoxinAPhase 3, Phase 1, Phase 2652
23Botulinum Toxins, Type APhase 3, Phase 1, Phase 2657
24Botulinum ToxinsPhase 3, Phase 1, Phase 2697
25Liver ExtractsPhase 3, Phase 2, Phase 14067
26Cholinergic AgentsPhase 3, Phase 1, Phase 23992
27Neurotransmitter AgentsPhase 3, Phase 2, Phase 118340
28onabotulinumtoxinAPhase 3, Phase 1, Phase 2652
29Peripheral Nervous System AgentsPhase 3, Phase 2, Phase 123689
30incobotulinumtoxinAPhase 3, Phase 1, Phase 2662
31Neuromuscular AgentsPhase 3, Phase 1, Phase 21180
32VitaminsPhase 35282
33Adjuvants, AnesthesiaPhase 31674
34Analgesics, OpioidPhase 33238
35Vitamin B ComplexPhase 34337
36pancreatic polypeptidePhase 320
37NarcoticsPhase 33646
38MicronutrientsPhase 36001
39Anesthetics, LocalPhase 2, Phase 33492
40Anesthetics, DissociativePhase 2, Phase 3544
41AnalgesicsPhase 2, Phase 311733
42Excitatory Amino Acid AntagonistsPhase 2, Phase 31347
43Excitatory Amino AcidsPhase 2, Phase 31362
44Trace ElementsPhase 36001
45HematinicsPhase 31684
46ColaNutraceuticalPhase 3, Phase 2, Phase 11946
47Vitamin B9NutraceuticalPhase 34392
48FolateNutraceuticalPhase 34392
49
IndinavirapprovedPhase 2110150378-17-95362440
Synonyms:
(1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-Pentonamide
(1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-pentonamide
(2S)-1-[(2S,4S)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide
150378-17-9
157810-81-6
157810-81-6 (sulfate (1:1) (salt))
166746-42-5
1c6y
1hsg
1hsh
1k6c
1sdt
1sdu
1sdv
1sgu
216884-06-9
2avo
2avs
2avv
2bpx
AC-20034
AC1L1U7I
AKOS000280989
BIDD:GT0378
BIDD:PXR0141
C07051
 
C36H47N5O4
CHEBI:44032
Compound J
Crixivan
Crixivan (TM)
DB00224
IDV
Indinavir (*1:1 Sulfate salt*)
Indinavir [USAN]
Indinavir anhydrous
Indinavir sulfate
Indinavir sulphate
Indinavir, Sulfate (1:1)
L 735524
L-735 524
L-735,524
L-735524
LS-173382
MK-639
MolPort-000-883-804
N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
NCGC00159460-02
NSC697197
Propolis & 4-Hydroxy-N-(2-hydroxy-2,3-dihydro-1H-1-indanyl)-N'-(1,1-dimethylethyl)-2-phenylmethyl-5-[4-(3-pyridylmethyl)-1-piperzinyl]hexanediamide
Propolis+Indinavir
RS-253
UNII-9MG78X43ZT
indinavir
50
Ritonavirapproved, investigationalPhase 2883155213-67-5392622
Synonyms:
1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
155213-67-5
1hxw
1sh9
5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S)-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate
5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate
538, ABT
A-84538
ABBOTT-84538
ABT 538
ABT 84538
ABT-538
ABT538
AC-733
AC1L94GB
AKOS000280930
Abbott 84538
BIDD:GT0387
BIDD:PXR0023
Bio-0093
C07240
C37H48N6O5S2
CHEBI:45409
CHEMBL163
CID392622
CPD000466395
D00427
D019438
 
DB00503
DRG-0244
FT-0082824
HMS2051B08
HSDB 7160
LS-148860
MLS000759541
MLS001424063
MolPort-000-883-877
N-[(2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl]-N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-L-valinamide
NCGC00159462-02
NSC693184
Norvir
Norvir (TM)
Norvir (TN)
Norvir Sec
RIT
RTV
Ritonavir
Ritonavir (JAN/USAN/INN)
Ritonavir [USAN]
Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS.
Ritonavirum
S1185_Selleck
SAM001246783
SMR000466395
STK634209
ZINC03944422
ritonavir

Interventional clinical trials:

(show top 50)    (show all 65)
idNameStatusNCT IDPhase
1The Role of Antibiotic Prophylaxis in Cleft Palate and Velopharyngeal Insufficiency RepairRecruitingNCT02688634Phase 4
2Does Sevoflurane Cause Genomic DamageRecruitingNCT03109119Phase 4
3Botulinum Toxin to Improve Results in Cleft Lip RepairUnknown statusNCT01429402Phase 3
4Assessing the Results of Lip Surgery in Patients With Cleft Lip and PalateCompletedNCT00070811Phase 2, Phase 3
5Infra-orbital Nerve Block for Post Operative Analgesia in Children Undergoing Cleft Lip Surgery.CompletedNCT02514980Phase 2, Phase 3
6Oral Cleft Prevention Trial in BrazilCompletedNCT00098319Phase 3
7Oral Cleft Prevention ProgramCompletedNCT00397917Phase 3
8Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate SurgeryCompletedNCT02923869Phase 2, Phase 3
9Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer PainCompletedNCT00538850Phase 3
10External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain MetastasesUnknown statusNCT00637637Phase 2
11Cleft Palate Surgery and Speech DevelopmentCompletedNCT00004639Phase 2
12Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?CompletedNCT00930124Phase 2
13Improvement of the Appearance of Cleft Lip Scars Using BotoxRecruitingNCT02247193Phase 1, Phase 2
14Effect of Platelet Rich Plasma (PRP) on the Esthetic Outcome and Scar Formation of Unilateral Cleft Lip RepairNot yet recruitingNCT02958306Phase 2
15Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced CancerCompletedNCT00045006Phase 1
16Motexafin Gadolinium and Doxorubicin in Treating Patients With Advanced CancerCompletedNCT00036790Phase 1
17MS-275 in Treating Patients With Advanced Solid Tumors or LymphomaCompletedNCT00020579Phase 1
18Thalidomide and Docetaxel in Treating Patients With Advanced CancerCompletedNCT00049296Phase 1
19Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate PatientsUnknown statusNCT01932164
20Comparison of Two Nasoalveolar Molding Techniques in Complete Unilateral Cleft Lip PatientUnknown statusNCT01883726
21Alveolar Bone Grafting Outcome Between Patient With and Without Orthodontic TreatmentUnknown statusNCT02454998
22Osteogenesis and Dental Eruption Through Electrical StimuliUnknown statusNCT00975208
23One-Piece Le Fort I Osteotomy Versus Segmental Le Fort I OsteotomyUnknown statusNCT01871623
24FaceBase BiorepositoryUnknown statusNCT01252264
25Functional Nasal Surgery at the Time of Le Fort I Osteotomy: A Prospective, Single-blind, Randomized TrialUnknown statusNCT01883687
263D Imaging of Hard and Soft Tissue in Orthognathic SurgeryUnknown statusNCT00285714
27IAN Injury After BSSO in Oral CleftsUnknown statusNCT01875965
28Articulation and Phonology in Children With Unilateral Cleft Lip and PalateCompletedNCT00829101
29A Study to Examine the Relationship Between Sleep Apnea and Cleft Lip/PalateCompletedNCT00156442
30Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate PatientsCompletedNCT02329509
31Effect Of Combination of Morphine+Fentanyl on Emergence Delirium in Patients of Cleft Lip and Palate RepairCompletedNCT03010540
32Primary Palatoplasty in Pediatric Patients - A Retrospective Review of Surgical OutcomesCompletedNCT01380171
33Tympanometric Analysis in Cleft PalateCompletedNCT01820689
34Systematic Pediatric Care for Oral Clefts - South AmericaCompletedNCT00097149
35Relational Development in Children With Cleft Lips and Palates: Influence of the Waiting Period Prior to the First Surgical Intervention and the Parents' Psychological Perception of the AbnormalityCompletedNCT00993993
36Svangerskap, Arv, og Miljo (Pregnancy, Heredity and Environment)CompletedNCT00340977
37Genetic Analysis of Fraser Syndrome and Fryns SyndromeCompletedNCT00032877
38Positive Exposure: A Photography and Video Intervention for Individuals With Craniofacial DifferencesCompletedNCT00340964
39Child's Adipose Cells: Capacity of Tissue RegenerationCompletedNCT02779205
40Study of the Experiences and Needs of Parents Continuing a Pregnancy Following a Prenatal Diagnosis of HolopresencephalyCompletedNCT00005016
41Sleep and Behavior in Children With Cleft PalateCompletedNCT01046591
42Genetic Analysis of Neural Tube and Orofacial Cleft Defects in the Irish PopulationCompletedNCT00341068
43Child and Infant Learning ProjectCompletedNCT00077831
44Physician-Initiated Stop-Smoking Program for Patients Receiving Treatment for Early-Stage CancerCompletedNCT00002520
45Study of Previously Collected and Stored Tissue Samples From Patients Previously Enrolled in a Completed National Cancer Institute Clinical TrialCompletedNCT00904514
46Clinical Effectiveness of Late Maxillary Protraction for Cleft Lip and PalateRecruitingNCT02789787
47Nasoalveolar Molding for Egyptian Cleft Lip Palate InfantsRecruitingNCT03029195
48Follow Ups of Parents With Infants With Cleft Lip and PalateRecruitingNCT02415361
49Biochemical and Histological Comparison of Nasal and Auricular Cartilage in the Fetus and Newborn With Cleft Lip CarrierRecruitingNCT02505360
50Efficiency of Novel Nasoalveolar Molding Method on Parents' Satisfaction in Unilateral Cleft InfantsRecruitingNCT02845193

Search NIH Clinical Center for Cleft Lip


Cochrane evidence based reviews: cleft lip

Genetic Tests for Cleft Lip

About this section

Anatomical Context for Cleft Lip

About this section

MalaCards organs/tissues related to Cleft Lip:

36
Bone, Heart, Skin, Breast, Kidney, Pituitary, Brain

Publications for Cleft Lip

About this section

Articles related to Cleft Lip:

(show top 50)    (show all 1134)
idTitleAuthorsYear
1
Imputation of Orofacial Clefting Data Identifies Novel Risk Loci and Sheds Light on the Genetic Background of Cleft Lip A+ Cleft Palate and Cleft Palate Only. (28087736)
2017
2
Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate. (28054174)
2017
3
Effect of Presurgical Nasoalveolar Molding on Nasal Symmetry in Unilateral Complete Cleft Lip/Palate Patients After Primary Cheiloplasty Without Concomitant Nasal Cartilage Dissection: Early Childhood Evaluation. (28085515)
2017
4
International multiphase mixed methods study protocol to develop a cross-cultural patient-reported outcome instrument for children and young adults with cleft lip and/or palate (CLEFT-Q). (28077415)
2017
5
Intraflagellar transport 88 (IFT88) is crucial for craniofacial development in mice and is a candidate gene for human cleft lip and palate. (28069795)
2017
6
Polymorphic variants in VAX1 and the risk of nonsyndromic cleft lip with or without cleft palate in a population from northern China. (28383424)
2017
7
Evaluation of lip force in patients with unilateral and bilateral cleft lip. (28087210)
2017
8
Assessment of complete unilateral cleft lip and palate patients: Determination of factors effecting dental arch relationships. (28012538)
2017
9
Association of single-nucleotide polymorphisms of CDH1 with nonsyndromic cleft lip with or without cleft palate in a northern Chinese Han population. (28151848)
2017
10
Dynamic facial asymmetry in patients with repaired cleft lip using 4D imaging (video stereophotogrammetry). (28011182)
2017
11
Skoog Primary Periosteoplasty versus Secondary Alveolar Bone Grafting in Unilateral Cleft Lip and Alveolus: Long-Term Effects on Alveolar Bone Formation and Maxillary Growth. (28027239)
2017
12
Comparing Modified Huddart-Bodenham Scoring System and GOSLON Yardstick to Assess Dental Arch Relationships in Unilateral Cleft Lip and Palate Patients. (28092164)
2017
13
Sequence variation in folate pathway genes and risks of human cleft lip with or without cleft palate. (27604992)
2016
14
Decolonisation of meticillin-resistant Staphylococcus aureus (MRSA) carriage in adopted children with cleft lip and palate. (27563747)
2016
15
Columellar Reconstruction: A New Technique for Median Cleft Lip Repair. (28005651)
2016
16
Reply to the Letters to the Editor Concerning the Article: Ana Isabel Costa, HAclder Morgado, Carlos Mariz, JosAc Manuel EstevALo-Costa. Secondary Alveolar Grafting and Cleft Lip and Palate. Acta Med Port 2016;29:210-6. (27649024)
2016
17
Phonology in Swedish-speaking 5-year-olds born with unilateral cleft lip and palate and the relationship with consonant production at 3 years of age. (27172850)
2016
18
Massively Increased Caries Susceptibility in an Irf6 Cleft Lip/Palate Model. (27927890)
2016
19
Unfavorable outcome of unilateral cleft lip repair. (27563597)
2016
20
Cleft sidedness and congenitally missing teeth in patients with cleft lip and palate patients. (27135068)
2016
21
Identification of Novel Variants in the PVRL1 Gene in Patients With Nonsyndromic Cleft Lip With or Without Cleft Palate. (26953873)
2016
22
Digital Three-Dimensional Automation of the Modified Huddart and Bodenham Scoring System for Patients With Cleft Lip and Palate. (27136074)
2016
23
Presurgical Nasoalveolar Molding Therapy Using Figueroa's NAM Technique in Unilateral Cleft Lip and Palate Patients: A Preliminary Study. (27617383)
2016
24
Presurgical nasoalveolar moulding: A boon in the management of cleft lip and palate. (28050103)
2016
25
Asymmetric Dental Development Investigated by Cone-Beam Computed Tomography in Patients With Unilateral Cleft Lip and Alveolus. (26274901)
2016
26
Survey of Parent Experiences in Prenatal Visits for Infants With Cleft Lip and Palate. (27632760)
2016
27
Comparison of dental arch dimensions in models of preschool children with cleft lip/palate repaired by means of surgery alone versus controls. (27749647)
2016
28
Measuring Symmetry in Children With Cleft Lip. Part 3: Quantifying Nasal Symmetry and Nasal Normalcy Before and After Unilateral Cleft Lip Repair. (27580380)
2016
29
Computer-Assisted Orthognathic Surgery for Patients with Cleft Lip/Palate: From Traditional Planning to Three-Dimensional Surgical Simulation. (27002726)
2016
30
Preliminary Analysis of the 3-Dimensional Morphology of the Upper Lip Configuration at the Completion of Facial Expressions in Healthy Japanese Young Adults and Patients With Cleft Lip. (27129635)
2016
31
MSX1 gene polymorphisms in Mexican patients with non-syndromic cleft lip/palate. (27729116)
2016
32
Suboptimal Performance in Cleft Lip/Palate Children- Who is Responsible? (27891420)
2016
33
Association of MSX1 c.*6Ca88>a88T Variant with Nonsyndromic Cleft Lip With or Without Cleft Palate in Turkish Patients. (27228008)
2016
34
MTR, MTRR, and MTHFR Gene Polymorphisms and Susceptibility to Nonsyndromic Cleft Lip With or Without Cleft Palate. (27167580)
2016
35
Assessing Angle's malocclusion among cleft lip and/or palate patients in Jammu. (27195223)
2016
36
Fordyce Happiness Program and Happiness in Mothers of Children with a Cleft Lip and Palate. (28008390)
2016
37
Discussion on: Nasoalveolar Molding Therapy for the Treatment of Unilateral Cleft Lip and Palate Improves Nasal Symmetry and Maxillary Alveolar Dimensions. (28005738)
2016
38
Gene Interactions Provide Evidence for Signaling Pathways Involved in Cleft Lip/Palate in Humans. (27154735)
2016
39
Rescue of lip switch flap at risk of necrosis due to venous congestion for cleft lip deformity. (27583269)
2016
40
Modified Activation Technique for Nasal Stent of Nasoalveolar Molding Appliance for Columellar Lengthening in Bilateral Cleft Lip/Palate. (27002917)
2016
41
Time trend of incidence rates of cleft lip/palate in Taiwan from 1994 to 2013. (27372171)
2016
42
The Slav-cleft: A three-center study of the outcome of treatment of cleft lip and palate. Part 1: Craniofacial morphology. (27663676)
2016
43
Quantitative assessment of healthy and reconstructed cleft lip using ultrasonography. (27134448)
2016
44
Irf6 directly regulates Klf17 in zebrafish periderm and Klf4 in murine oral epithelium, and dominant-negative KLF4 variants are present in patients with cleft lip and palate. (26692521)
2016
45
Parental experience caring for cleft lip and palate infants with nasoalveolar moulding. (27144651)
2016
46
The Role of the Velopharyngeal Sphincter in the Speech of Patients with Cleft Palate or Cleft Lip and Palate Using Perceptual Methods. (28028412)
2016
47
Three-dimensional Printing of Models of Cleft Lip and Palate. (27200251)
2016
48
Management of feeding Problem in a Patient with Cleft Lip/Palate. (27365936)
2016
49
Recurrence of split hand/foot malformation, cleft lip/palate, and severe urogenital abnormalities due to germline mosaicism for TP63 mutation. (27351625)
2016
50
Novel variant in the TP63 gene associated to ankyloblepharon-ectodermal dysplasia-cleft lip/palate (AEC) syndrome. (27485918)
2016

Variations for Cleft Lip

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Expression for genes affiliated with Cleft Lip

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Search GEO for disease gene expression data for Cleft Lip.

Pathways for genes affiliated with Cleft Lip

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GO Terms for genes affiliated with Cleft Lip

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Biological processes related to Cleft Lip according to GeneCards Suite gene sharing:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1keratinocyte proliferationGO:004361610.9IRF6, TP63
2BMP signaling pathway involved in heart developmentGO:006131210.8BMP4, MSX1
3epithelial to mesenchymal transition involved in endocardial cushion formationGO:000319810.8BMP4, MSX1
4anatomical structure formation involved in morphogenesisGO:004864610.8BMP4, TP63
5cloacal septationGO:006019710.8BMP4, TP63
6middle ear morphogenesisGO:004247410.8FGFR1, MSX1
7camera-type eye morphogenesisGO:004859310.8BMP4, NECTIN1
8positive regulation of SMAD protein import into nucleusGO:006039110.8BMP4, TGFB3
9folic acid metabolic processGO:004665510.7MTHFR, MTRR
10methionine metabolic processGO:000655510.7MTHFR, MTRR
11face morphogenesisGO:006032510.7MSX1, PAX9, TGFB3
12methionine biosynthetic processGO:000908610.7MTR, MTRR
13organ inductionGO:000175910.6BMP4, FGFR1
14BMP signaling pathwayGO:003050910.6BMP4, MSX1, TGFB3
15odontogenesis of dentin-containing toothGO:004247510.6BMP4, MSX1, TP63
16regulation of odontogenesisGO:004248110.6MSX1, PAX9
17palate developmentGO:006002110.5MSX1, SATB2, TGFB3
18smooth muscle tissue developmentGO:004874510.5BMP4, TP63
19cartilage developmentGO:005121610.5BMP4, MSX1, SATB2
20salivary gland morphogenesisGO:000743510.5FGFR1, TGFB3
21prostate gland developmentGO:003085010.4RARA, TP63
22embryonic limb morphogenesisGO:003032610.4BMP4, FGFR1, MSX1, TP63
23odontogenesisGO:004247610.3BMP4, MSX1, PAX9, TGFB3
24sulfur amino acid metabolic processGO:000009610.3MTR, MTRR
25positive regulation of neuron differentiationGO:004566610.3BMP4, FGFR1, RARA
26negative regulation of apoptotic processGO:004306610.1BMP4, MSX1, RARA, TGFA, TP63
27negative regulation of cell proliferationGO:000828510.1BMP4, IRF6, MSX1, RARA, TGFB3
28negative regulation of transcription, DNA-templatedGO:004589210.0BMP4, MSX1, PAX9, RARA, TP63
29positive regulation of transcription, DNA-templatedGO:00458939.8BMP4, IRF6, RARA, TGFB3, TP63
30negative regulation of transcription from RNA polymerase II promoterGO:00001229.6BMP4, FGFR1, MSX1, RARA, SATB2, TP63
31ureteric bud developmentGO:00016579.5BMP4, FGFR1, RARA
32positive regulation of transcription from RNA polymerase II promoterGO:00459449.4BMP4, MSX1, PAX9, RARA, SATB2, TGFB3

Molecular functions related to Cleft Lip according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulatory region DNA bindingGO:00009759.9IRF6, RARA

Sources for Cleft Lip

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet