CPI
MCID: CLF027
MIFTS: 55

Cleft Palate, Isolated (CPI) malady

Categories: Genetic diseases (common), Oral diseases, Neuronal diseases, Mental diseases

Aliases & Classifications for Cleft Palate, Isolated

About this section

Aliases & Descriptions for Cleft Palate, Isolated:

Name: Cleft Palate, Isolated 52 24 68
Cleft Palate 11 27 50 39 13 68
Cleft Palate Isolated 70 27
Isolated Cleft Palate 11 13
Uranostaphyloschisis 11 68
 
Cleft Palate Isolated with Mental Retardation 70
Palatoschisis 11
Cleft Velum 11
Cpi 70
Cp 70

Characteristics:

HPO:

64
cleft palate, isolated:
Inheritance: autosomal dominant inheritance

Classifications:



Summaries for Cleft Palate, Isolated

About this section
UniProtKB/Swiss-Prot:70 Cleft palate isolated: A congenital fissure of the soft and/or hard palate, due to faulty fusion. Isolated cleft palate is not associated with cleft lips. Some patients may manifest other craniofacial dysmorphic features, mental retardation, and osteoporosis.

MalaCards based summary: Cleft Palate, Isolated, also known as cleft palate, is related to orofacial cleft 6 and cleft lip +/- cleft palate, and has symptoms including seizures, seizures and cleft palate. An important gene associated with Cleft Palate, Isolated is UBB (Ubiquitin B), and among its related pathways are Hypothetical Craniofacial Development Pathway and Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers. Related mouse phenotypes are no phenotypic analysis and endocrine/exocrine gland.

Disease Ontology:11 An orofacial cleft characterized by a fissure of the soft and/or hard palate, due to faulty fusion of the two plates of the skull that form the hard palate.

OMIM:52 Cleft palate as an isolated malformation behaves as an entity distinct from cleft lip with or without cleft palate (see... (119540) more...

Related Diseases for Cleft Palate, Isolated

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Diseases related to Cleft Palate, Isolated via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 148)
idRelated DiseaseScoreTop Affiliating Genes
1orofacial cleft 632.6IRF6, SATB2, TP63
2cleft lip +/- cleft palate12.3
3cleft palate with ankyloglossia12.3
4microtia, hearing impairment, and cleft palate12.2
5cleft palate, psychomotor retardation, and distinctive facial features12.1
6hydrocephalus-cleft palate-joint contractures syndrome12.1
7submucosal cleft palate12.1
8cleft palate, cardiac defect, genital anomalies, and ectrodactyly12.0
9syngnathia cleft palate12.0
10omphalocele-cleft palate syndrome, lethal12.0
11cleft palate x-linked12.0
12dominant cleft palate11.9
13ankyloblepharon filiforme adnatum and cleft palate11.9
14acromegaloid features, overgrowth, cleft palate, and hernia11.9
15hydronephrosis, congenital, with cleft palate, characteristic facies, hypotonia, and mental retardation11.9
16cleft palate, midfacial hypoplasia, triangular facies, and sensorineural hearing loss11.9
17palant cleft palate syndrome11.9
18native american myopathy11.9
19spondyloepiphyseal dysplasia with coronal craniosynostosis, cataracts, cleft palate, and mental retardation11.8
20cleft palate, deafness, and oligodontia11.8
21cleft palate short stature vertebral anomalies11.8
22dysmorphism cleft palate loose skin11.8
23hypotelorism cleft palate hypospadias11.8
24anophthalmia cleft palate micrognathia11.8
25cleft palate cardiac defect ectrodactyly11.8
26cleft palate colobomata radial synostosis deafness11.8
27cleft palate heart disease polydactyly absent tibia11.8
28cleft palate stapes fixation oligodontia11.8
29craniosynostosis arthrogryposis cleft palate11.8
30cystic hygroma lethal cleft palate11.8
31hirschsprung microcephaly cleft palate11.8
32mesomelic dwarfism cleft palate camptodactyly11.8
33short limbs subluxed knees cleft palate11.8
34short stature monodactylous ectrodactyly cleft palate11.8
35microcephaly-cleft palate syndrome11.8
36blepharoptosis-cleft palate-ectrodactyly-dental anomalies syndrome11.8
37auricular abnormalities-cleft lip with or without cleft palate-ocular abnormalities syndrome11.8
38cleft soft palate11.8
39syngnathia11.7
40cleft lip/palate11.7
41orofacial cleft 1111.7
42aceruloplasminemia11.7
43mandibulofacial dysostosis, guion-almeida type11.7
44pierre robin syndrome11.6
45abruzzo-erickson syndrome11.6
46bamforth-lazarus syndrome11.6
47arthrogryposis, distal, type 311.6
48cleft lip/palate-ectodermal dysplasia syndrome11.5
49isolated pierre robin sequence11.5
50rapp-hodgkin syndrome11.5

Graphical network of the top 20 diseases related to Cleft Palate, Isolated:



Diseases related to cleft palate, isolated

Symptoms & Phenotypes for Cleft Palate, Isolated

About this section

Symptoms by clinical synopsis from OMIM:

119540

Clinical features from OMIM:

119540

Human phenotypes related to Cleft Palate, Isolated:

 64 (show all 8)
id Description HPO Frequency HPO Source Accession
1 cleft palate64 HP:0000175
2 gingival overgrowth64 HP:0000212
3 micrognathia64 HP:0000347
4 seizures64 HP:0001250
5 intellectual disability, profound64 HP:0002187
6 anterior open-bite malocclusion64 HP:0009102
7 overbite64 HP:0011094
8 non-midline cleft lip64 HP:0100335

UMLS symptoms related to Cleft Palate, Isolated:


seizures

MGI Mouse Phenotypes related to Cleft Palate, Isolated according to GeneCards Suite gene sharing:

41 (show all 17)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030129.3BMP4, FGFR1, FGFR2, FOXC2, GABRB3, MSX1
2MP:00053799.1BMP4, FGFR1, FGFR2, FOXE1, MSX1, SATB2
3MP:00028739.1BMP4, COL2A1, FGFR1, FGFR2, FOXC2, GABRB3
4MP:00053808.8BMP4, COL2A1, FGFR1, FGFR2, FOXC2, IRF6
5MP:00053858.7BMP4, COL2A1, FGFR1, FGFR2, FOXC2, MSX1
6MP:00107718.7BMP4, FGFR1, FGFR2, FOXE1, IRF6, MSX1
7MP:00053718.7BMP4, COL11A1, COL2A1, FGFR1, FGFR2, IRF6
8MP:00053888.7BMP4, COL11A1, COL2A1, FGFR2, FOXC2, MSX1
9MP:00053778.6BMP4, COL11A1, COL11A2, COL2A1, FGFR1, FGFR2
10MP:00036318.6BMP4, COL11A1, COL2A1, FGFR1, FGFR2, FOXC2
11MP:00053768.2BMP4, COL2A1, FGFR1, FGFR2, FOXC2, FOXE1
12MP:00053817.5BMP4, COL11A1, COL2A1, FGFR1, FGFR2, FOXC2
13MP:00053917.3BMP4, COL2A1, FGFR1, FGFR2, FOXC2, MSX1
14MP:00107687.2BMP4, COL11A1, COL2A1, FGFR1, FGFR2, FOXC2
15MP:00053907.0BMP4, COL11A1, COL11A2, COL2A1, FGFR1, FGFR2
16MP:00053826.8BMP4, COL11A1, COL11A2, COL2A1, FGFR1, FGFR2
17MP:00053786.6BMP4, COL11A1, COL11A2, COL2A1, FGFR1, FGFR2

Drugs & Therapeutics for Cleft Palate, Isolated

About this section

Drugs for Cleft Palate, Isolated (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 89)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Tranexamic AcidapprovedPhase 42771197-18-85526
Synonyms:
08455_FLUKA
1197-17-7
1197-18-8
1ceb
3-14-00-00868 (Beilstein Handbook Reference)
4-(Aminomethyl)-Cyclohexanecarboxylic Acid
4-(Aminomethyl)cyclohexanecarboxylic acid
4-(aminomethyl)cyclohexane-1-carboxylic acid
857653_ALDRICH
A0236
AB00052260
AB1003647
AC-4687
AC1L1KJH
AC1Q50F3
AC1Q546D
AC1Q5U04
ALBB-006013
AMCA
AMCHA
AMH
AR-1F6595
Acide tranexamique
Acide tranexamique [INN-French]
Acido tranexamico
Acido tranexamico [INN-Spanish]
Acidum tranexamicum
Acidum tranexamicum [INN-Latin]
Amikapron
Amstat
Anvitoff
BAY 3517
BPBio1_000069
BRN 2207452
BSPBio_000061
BSPBio_002837
CAS-1197-18-8
CHEBI:48669
CHEMBL292500
CHEMBL877
CID5526
CL 65336
CL-65336
Carxamin
Cyclocapron
Cyklokapron
Cyklokapron (TN)
D01136
DB00302
DV 79
DV-79
DV79
DivK1c_000655
EINECS 214-818-2
Emorhalt
Exacyl
Frenolyse
HMS1568D03
HMS1921F08
HMS2092P03
HMS502A17
Hexapromin
Hexatron
I04-0993
IDI1_000655
KABI 2161
KBio1_000655
KBio2_001871
KBio2_004439
KBio2_007007
KBio3_002337
KBioGR_000511
 
KBioSS_001871
LS-56611
LS-56612
LT00159441
Mastop
MolPort-001-792-390
MolPort-002-512-008
NCGC00016569-01
NCGC00016569-02
NCGC00016569-03
NCGC00094944-01
NCGC00094944-02
NINDS_000655
NSC 291305
NSC291305
Oprea1_786414
Prestwick0_000171
Prestwick1_000171
Prestwick2_000171
Prestwick3_000171
Prestwick_476
RP 18,429
Rikavarin
Rikavarin (TN)
Rikavarin-S
SPBio_000689
SPBio_001982
SPECTRUM1502026
STK503668
STOCK1N-16183
Spectrum2_000655
Spectrum3_001189
Spectrum4_000046
Spectrum5_001258
Spectrum_001391
Spiramin
Tamcha
Tranex
Tranexamate
Tranexamic acid (JP15/USAN/INN)
Tranexamic acid [USAN:INN:BAN:JAN]
Tranexamic acid cis-form
Tranexamsaeure
Tranexan
Tranexmic acid
Tranhexamic acid
Trans AMCHA
Trans-1-(Aminomethyl)cyclohexane-4-carboxylic acid
Trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid
Trans-p-(Aminomethyl)cyclohexanecarboxylic
Transamin
Transamin (TN)
Transamlon
Trasamlon
UNII-6T84R30KC1
Ugurol
WLN: L6TJ AVQ D1Z -T
cis-4-(Aminomethyl)cyclohexanecarboxylic acid
cis-4-Aminomethylcyclohexane-1-carboxylic acid
cis-AMCHA
t-AMCHA
tranexamic acid
tranexmic acid
trans-1-Aminomethylcyclohexane-4-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-1-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-carboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid ester
trans-4-Aminomethylcyclohexane-1-carboxylic acid
trans-4-aminomethylcyclohexane-1-carboxylic acid
trans-Amcha
trans-Tranexamic acid
trans-p-(Aminomethyl)cyclohexanecarboxylic acid
2
Codeineapproved, illicitPhase 47776-57-35284371
Synonyms:
(-)-Codeine
(5alpha,6alpha)-17-methyl-3-(methyloxy)-7,8-didehydro-4,5-epoxymorphinan-6-ol
(5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
(5α,6α)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
(6alpha,13alpha)-3-methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6-ol
(−)-Codeine
3-Methylmorphin
3-methoxy-17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-6alpha-ol
3-methylmorphine
3-o-methylmorphine monohydrate
41444-62-6 (PO4)
7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methylmorphinan-6-alpha-ol
7,8-didehydro-4,5-ep oxy-3-methoxy-17-methylmorphinan-6-ol
7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-(5alpha, 6alpha)-morphinan 6-ol
7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methylmorphinan-6alpha-ol
7,8-didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol
76-57-3
AC-11114
AC1Q4DTD
Actacode
Ardinex
C06174
C1653_FLUKA
C1653_SIGMA
C5901_FLUKA
C5901_SIGMA
CCRIS 7555
CHEBI:16714
CHEMBL485
CID5284371
CODEINE (SEE ALSO: CODEINE PHOSPHATE (CAS 52-28-8))
CODEINE BASE
Calcidrine
Codalgin Forte Codate
Codein
Codeine
Codeine (anhydrous)
Codeine [BAN]
Codeine anhydrous
Codeine solution
 
Codeinum
Codeína
Codicept
Coducept
Codéine
DB00318
EINECS 200-969-1
HSDB 3043
Isocodeine
L-Codeine
LS-1695
Methylmorphine
MolPort-002-506-913
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5-alpha,6-alpha)- (9CI)
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)- (9CI)
Morphinan-6alpha-ol, 7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methyl- (8CI)
Morphine 3-methyl ether
Morphine monomethyl ether
Morphine-3-methyl ester
Morphine-3-methyl ether
N-Methylmorphine
N-methyl norcodine
N-methylnorcodeine
Norcodeine, N-Methyl
Norcodeine, N-methyl
Norcodine, N-Methyl
Norcodine, N-methyl
Novahistine DH
O(3)-methylmorphine
O3-Methylmorphine
Robitussin AC
STOCK1N-42851
codeina
codeine
codeinum
l-Codeine
metilmorfina
morphine 3-methyl ether
morphine monomethy l ether
morphine monomethyl ether
morphine-3-methyl ether
nchembio.317-comp2
3
Guaifenesinapproved, vet_approvedPhase 464193-14-13516
Synonyms:
3-(2-Methoxyphenoxy)-1,2-propanediol
3-(O-Methoxyphenoxy)-1,2-propanediol
3-(O-Methoxyphenoxy)-propanediol-1,2
3-O-Methoxyphenoxypropane 1:2-diol
Actifed C
Aeronesin
Amonidren
Amonidrin
Aresol
Benylin-E
Bronchol
Glycerin ether
Glycerin guaiacolate
Glycero-guaiacol ether
Glycerol a-(2-methoxyphenyl) ether
Glycerol a-(O-methoxyphenyl)ether
Glycerol a-guaiacyl ether
Glycerol a-guiacyl ether
Glycerol a-monoguaiacol ether
Glycerol guaiacolate
Glycerol mono(2-methoxyphenyl) ether
Glycerol-a-guajakolether
Glycerol-alpha-guajakolether
Glyceryl guaiacol
Glyceryl guaiacol ether
Glyceryl guaiacolate
Glyceryl guaiacolate ether
Glyceryl guaiacyl ether
Glyceryl guaicolate
Glyceryl guiacolate
 
Glycerylguaiacol
Guaiacol glycerol ether
Guaiacol glyceryl ether
Guaiacolglicerinetere
Guaiacuran
Guaiacurane
Guaiacyl glyceryl ether
Guaiamar
Guaianesin
Guaicol glycerine ether
Guaicol glyceryl ether
Guaifenesin
Guaifenesine
Guaiphenesin
Guaiphenesine
Guaiphesin
Hustosil
Methoxypropanediol
Methphenoxydiol
Metossipropandiolo
O-Methoxyphenyl glyceryl ether
Organidin NR
Pneumomist
Propanosedyl
Reduton
Robitussin
a-Glyceryl guaiacol ether
a-Glyceryl guaiacolate ether
alpha-Glyceryl guaiacol ether
alpha-Glyceryl guaiacolate ether
guaiphenesin
p-Cresyl acetate
4
Amoxicillinapproved, vet_approvedPhase 446526787-78-033613, 2171
Synonyms:
(-)-6-(2-Amino-2-(P-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo-(3.2.0)heptane-2-carboxylic acid
(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
26787-78-0
33911-69-2
34642-77-8 (mono-hydrochloride salt)
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-(p-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-, D- (8CI)
6-(D-(-)-alpha-Amino-p-hydroxyphenylacetamido)penicillanic acid
6-(D-(-)-p-Hydroxy-alpha-aminobenzyl)penicillin
6-(a-Amino-4-hydroxyphenylacetamido)penicillanic acid
6-(p-Hydroxy-alpha-aminophenylacetamido)penicillanic acid
6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid
6-[[Amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 9CI
61336-70-7 (TRIHYDRATE)
6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carbonyl
6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid
71447-36-4
81030-75-3
AC-12263
AC1L1PY2
AMC
AMOXICILLIN CRYSTALLINE
AMOXICILLIN PEDIATRIC
AMPC
AUGMENTIN '125'
AUGMENTIN '200'
AUGMENTIN '250'
AUGMENTIN '400'
AUGMENTIN '500'
AUGMENTIN '875'
AUGMENTIN ES-600
AX
Actimoxi
Almodan
Ambap26787-78-0
Amix
Amoclen
Amolin
Amopen
Amopenixin
Amoram
Amox
Amox 250 Cap 250mg
Amox 500 Cap 500mg
Amox S 125 Sus 125mg/5ml
Amox S 250 Sus 250mg/5ml
Amoxi
Amoxi-Mast
Amoxi-mast
Amoxibiotic
Amoxicaps
Amoxicilina
Amoxicilina [INN-Spanish]
Amoxicillin (INN)
Amoxicillin (TN)
Amoxicillin (anhydrous)
Amoxicillin (inn)
Amoxicillin Trihydrate
Amoxicillin and clavulanate potassium
Amoxicillin anhydrous
Amoxicillin pediatric
Amoxicillin trihydrate
Amoxicillin(usan)
Amoxicilline
Amoxicilline [INN-French]
Amoxicilline [INN]
Amoxicilline [inn]
Amoxicillinum
Amoxicillinum [INN-Latin]
Amoxid
Amoxiden
Amoxil
Amoxivet
Amoxycillin
Amoxycillin Trihydrate
Amoxycillin trihydrate
Amoxycillin, BAN
Amoxymed
Amrit
Anemolin
Apo-Amoxi
Apo-Amoxi Cap 250mg
Apo-Amoxi Cap 500mg
Apo-Amoxi Pwr for Susp 125mg/5ml
Apo-Amoxi Pwr for Susp 250mg/5ml
Apo-amoxi
Apo-amoxi sugar free
Aspenil
BL-P 1410
BLP 1410
BPBio1_000499
BRD-K55044200-001-03-9
BRL 2333
BRL-2333
BSPBio_000453
 
Biomox
Bristamox
C06827
CHEBI:2676
CHEBI:53712
CHEMBL1082
CID33613
CPD000058707
Cemoxin
Clamoxyl
Clamoxyl (SKB)
D-(-)-alpha-Amino-p-hydroxybenzyl penicillin
D-(-)-alpha-Amino-p-hydroxybenzylpenicillin
D-(alpha-Amino-p-hydroxybenzyl)penicillin
D-2-Amino-2-(4-hydroxyphenyl)acetamidopenicillanic acid
D-Amoxicillin
D07452
DB01060
Delacillin
DisperMox
Dispermox
EINECS 248-003-8
Efpenix
Flemoxin
Galenamox
Gen-Amoxicillin 250mg
Gen-Amoxicillin 500mg
HMS1569G15
HSDB 3204
Hiconcil
Histocillin
Hydroxyampicillin
Ibiamox
Imacillin
LS-149721
Lamoxy
Larotid
MLS000028632
MLS002222248
Metafarma capsules
Metifarma capsules
MolPort-003-981-182
MolPort-005-933-687
Moxacin
Moxal
Moxatag
NCGC00179554-01
NSC 277174
NSC277174
Novamoxin Cap 250mg
Novamoxin Cap 500mg
Novamoxin Sus 125mg/5ml
Novamoxin Sus 250mg/5ml
Nu-Amoxi Cap 250mg
Nu-Amoxi Cap 500mg
Nu-Amoxi Sus 125/5ml
Nu-Amoxi Sus 250mg/5ml
Ospamox
P-Hydroxyampicillin
PHL-amoxicillin
PMS-amoxicillin
Pamoxicillin
Piramox
Polymox
Prestwick0_000357
Prestwick1_000357
Prestwick2_000357
Prestwick3_000357
Prestwick_713
Prevpac
Pro Amox Pwr for Oral Susp 125mg/5ml
Pro Amox-250 Cap 250mg
Pro Amox-500 Cap 500mg
Pro-Amox-250 Orl Sus 250mg/5ml
R-Hydroxyampicillin
Rimoxallin
Ro 10-8756
Robamox
SAM002264592
SMR000058707
SPBio_002374
Sauracillin
Sawamox PM
Sumox
Tolodina
Trimox
Unicillin
Utimox
Vetramox
Wymox
Zimox
alpha-Amino-p-hydroxybenzylpenicillin
amoxicillanyl
amoxicillin
p-Hydroxyampicillin
α-amino-p-hydroxybenzylpenicillin
5
Propofolapproved, investigational, vet_approvedPhase 410822078-54-84943
Synonyms:
2, 6-Diisopropylphenol
2,6 Diisopropylphenol
2,6-Bis(1-methylethyl)phenol
2,6-Bis(Isopropyl)-phenol
2,6-DIISOPROPYLPHENOL
2,6-Diisopropyl phenol
2,6-Diisopropylphenol
2,6-bis(1-methylethyl)-phenol
2,6-di(propan-2-yl)phenol
2078-54-8
28449-97-0
4-06-00-03435 (Beilstein Handbook Reference)
50356-15-5
AB00513968
AC-2038
AC1L1J9Y
AC1Q1OUI
AI3-26295
AM-149
Abbott Brand of Propofol
Alpha Brand of Propofol
Ampofol
Aquafol
Astra Brand of Propofol
AstraZeneca Brand of Propofol
BIDD:GT0436
BPBio1_000950
BPBio1_000969
BRD-K82255054-001-03-5
BRN 1866484
BSPBio_000862
Biomol-NT_000248
Braun Brand of Propofol
C07523
C12H18O
CAS-2078-54-8
CCRIS 9000
CHEBI:44915
CHEMBL526
CID4943
CPD-11437
CPD000059151
Curamed Brand of Propofol
D00549
D015742
D0617
D126608
D126608_ALDRICH
DB00818
DDS-04F
Diisopropylphenol
Dipravan
Diprivan
Diprivan (TN)
Diprivan Injectable emulsion
Disoprivan
Disoprofol
EINECS 218-206-6
EU-0100437
Fresenius Brand of Propofol
Fresenius Kabi Brand of Propofol
Fresofol
HMS1570L04
HMS2089O21
HMS2094E17
 
HSDB 7123
ICI 35,868
ICI 35868
ICI-35,868
ICI-35868
ICI35,868
ICI35868
InChI=1/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H
Ivofol
Jsp004266
Juste Brand of Propofol
LS-996
Lopac-D126608
Lopac0_000437
MLS001066348
MLS001335999
MLS002454360
MolPort-001-794-517
NCGC00015389-01
NCGC00015389-02
NCGC00015389-04
NCGC00015389-09
NCGC00091538-01
NCGC00091538-02
NCGC00091538-03
NCGC00091538-04
NCGC00091538-05
NCGC00091538-06
NSC 5105
NSC5105
PFL
Parnell Brand of Propofol
Pisa Brand of Propofol
Prestwick0_000931
Prestwick1_000931
Prestwick2_000931
Prestwick3_000931
Propofol
Propofol (JAN/USAN/INN)
Propofol Abbott
Propofol Fresenius
Propofol IDD-D
Propofol MCT
Propofol Rovi
Propofol [USAN:INN:BAN]
Propofol(2,6-Diisopropylphenol)
Propofol-Lipuro
Propofolum
Propofolum [Latin]
Rapinovet
Recofol
Rovi Brand of Propofol
S01-0189
SAM002264610
SMR000059151
SPBio_003031
SPECTRUM1505022
ST50405911
Schering Brand of Propofol
UNII-YI7VU623SF
W505102_ALDRICH
ZD-0859
ZINC00968303
Zeneca Brand of Propofol
ghl.PD_Mitscher_leg0.558
nchembio.552-comp7
propofol
6
Sevofluraneapproved, vet_approvedPhase 450828523-86-65206
Synonyms:
1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane
28523-86-6
AC-15484
AC1L1JU0
BRN 2041023
Bax 3084
C009250
C07520
C4H3F7O
CHEBI:9130
CHEMBL1200694
CID5206
D00547
DB01236
F0691
Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl Ether
Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
I14-13357
LS-67851
MR6S4
 
MR_6S4
MolPort-001-775-746
NCGC00167421-01
PC4681
Sevofluran
Sevoflurane
Sevoflurane (JAN/USAN/INN)
Sevoflurane [USAN:INN:BAN:JAN]
Sevoflurano
Sevoflurano [INN-Spanish]
Sevofluranum
Sevofluranum [INN-Latin]
Sevofrane
Sevorane
Sojourn
UNII-38LVP0K73A
Ultane
Ultane (TN)
ZINC01530810
fluoromethyl hexafluoroisopropyl ether
fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
sevoflurane
7
Dexmedetomidineapproved, vet_approvedPhase 459276631-46-4, 113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
 
Dexdor (T)
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex (TN)
Tocris-2023
ZINC04632106
8AnalgesicsPhase 4, Phase 3, Phase 211733
9Antibiotics, AntitubercularPhase 4, Phase 27180
10Anti-Infective AgentsPhase 4, Phase 222062
11AnestheticsPhase 4, Phase 2, Phase 3, Phase 19596
12Analgesics, Non-NarcoticPhase 4, Phase 3, Phase 26501
13Anti-Bacterial AgentsPhase 4, Phase 211226
14Anesthetics, GeneralPhase 42934
15Antitubercular AgentsPhase 4, Phase 21343
16Anesthetics, IntravenousPhase 42538
17NarcoticsPhase 43646
18Chlorpheniramine, phenylpropanolamine drug combinationPhase 4641
19Antitussive AgentsPhase 4542
20Central Nervous System DepressantsPhase 4, Phase 2, Phase 313403
21HemostaticsPhase 41443
22Analgesics, OpioidPhase 43238
23CoagulantsPhase 41500
24Antifibrinolytic AgentsPhase 4484
25Respiratory System AgentsPhase 44997
26Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 3, Phase 123689
27Hypnotics and SedativesPhase 42616
28Neurotransmitter AgentsPhase 4, Phase 1, Phase 218340
29Fibrin Tissue AdhesivePhase 4148
30Anesthetics, InhalationPhase 4684
31Platelet Aggregation InhibitorsPhase 42516
32Adrenergic alpha-AgonistsPhase 41734
33Adrenergic alpha-2 Receptor AgonistsPhase 4980
34Adrenergic AgentsPhase 45352
35Adrenergic AgonistsPhase 43027
36
KetorolacapprovedPhase 332374103-06-3, 66635-83-43826
Synonyms:
(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
(+-)-Ketorolac
(+-)-isomer
(.+/-.)-2,3-Dihydro-5-benzoyl-1H-pyrrolizine-1-carboxylic acid
1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro
5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
5-Benzoyl-1,2-dihydro-3H-pyrrolo(1,2a)pyrrole-1-carboxylic acid
5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
66635-83-4
74103-06-3
AB00053682
AC-545
AC1L1GSW
BRD-A40639672-234-05-7
C07062
CHEBI:105080
CHEMBL469
CID3826
D020910
D08104
DB00465
 
I14-2832
Ketoralac
Ketorolac
Ketorolac (INN)
Ketorolac Tromethamine
Ketorolac [INN:BAN]
Ketorolaco
Ketorolaco [Spanish]
Ketorolacum
Ketorolacum [Latin]
Kétorolac
LS-139094
Macril
MolPort-005-933-093
NCGC00185990-01
RS 37619
RS-37619
SBB067312
STL018674
Toradol (TN)
UNII-YZI5105V0L
ketorolac
rac-Ketorolac
37
LevobupivacaineapprovedPhase 2, Phase 317227262-47-192253
Synonyms:
(-)-Bupivacaine
(-)-bupivacaine
(2S)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(S)-1-Butyl-2',6'-pipecoloxylidide
(S)-Bupivacaine
(S)-bupivacaine
27262-47-1
27262-48-2
AC1L3NQM
BIDD:GT0471
C07887
C18H28N2O
CAS-18010-40-7
CHEBI:6149
CID92253
D08116
 
DB01002
L(-)-Bupivacaine
L-(-)-1-Butyl-2',6'-pipecoloxylidide
L-(-)-Bupivacaine
L-(-)-bupivacaine
LS-109843
LS-187025
LS-187789
Levobupivacaine
Levobupivacaine (INN)
Levobupivacaine [INN:BAN]
Levobupivacaine hydrochloride
MolPort-004-959-713
NCGC00016733-01
NCGC00159482-02
Novabupi
Novabupi (TN)
38
Epinephrineapproved, vet_approvedPhase 398551-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
39
Bupivacaineapproved, investigationalPhase 2, Phase 312332180-92-9, 38396-39-32474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
(±)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
 
DepoBupivacaine
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
racemic bupivacaine
40
leucovorinapproved, NutraceuticalPhase 3323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
41
Folic Acidapproved, nutraceutical, vet_approvedPhase 3439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
42Cyclooxygenase InhibitorsPhase 32870
43Antirheumatic AgentsPhase 310956
44RacepinephrinePhase 3985
45Anti-Inflammatory Agents, Non-SteroidalPhase 34443
46Pharmaceutical SolutionsPhase 3, Phase 28192
47Epinephryl boratePhase 3985
48Ketorolac TromethaminePhase 3323
49Vitamin B ComplexPhase 34337
50Anesthetics, LocalPhase 2, Phase 33492

Interventional clinical trials:

(show top 50)    (show all 91)
idNameStatusNCT IDPhase
1Double Blind Randomized Study Into the Efficacy of Codeine Phosphate Analgesia After Cleft Palate Repair in InfantsCompletedNCT00386269Phase 4
2Acid Tranexamic Effectiveness in Reducing the Intraoperative Bleeding in PalatoplastyCompletedNCT02422056Phase 4
3The Role of Antibiotic Prophylaxis in Cleft Palate and Velopharyngeal Insufficiency RepairRecruitingNCT02688634Phase 4
4The Use of Fibrin Sealant to Reduce Post Operative Pain in Cleft Palate SurgeryRecruitingNCT02953145Phase 4
5Does Sevoflurane Cause Genomic DamageRecruitingNCT03109119Phase 4
6Dexmedetomidine vs Placebo for Pediatric Cleft Palate RepairNot yet recruitingNCT02915042Phase 4
7Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate SurgeryCompletedNCT02923869Phase 2, Phase 3
8Oral Cleft Prevention Trial in BrazilCompletedNCT00098319Phase 3
9Oral Cleft Prevention ProgramCompletedNCT00397917Phase 3
10A Comparison of Bupivacaine and Ketorolac for Postoperative Analgesia After Iliac Crest Bone HarvestingCompletedNCT00405262Phase 3
11Assessing the Results of Lip Surgery in Patients With Cleft Lip and PalateCompletedNCT00070811Phase 2, Phase 3
12Phase II Study of Dietary Cholesterol for Smith-Lemli-Opitz SyndromeUnknown statusNCT00004347Phase 2
13Preoperative Antibiotics StudyCompletedNCT00760006Phase 2
14Cleft Palate Surgery and Speech DevelopmentCompletedNCT00004639Phase 2
15Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?CompletedNCT00930124Phase 2
16Cell Therapy for Craniofacial Bone DefectsCompletedNCT01616953Phase 1, Phase 2
17Does Use of Rigid Fixation After Removing Distraction Osteogenesis Device Reduce the Relapse?CompletedNCT02350803Phase 2
18Short-term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz SyndromeCompletedNCT00114634Phase 2
19Treatment of the Cholesterol Defect in Smith-Lemli-Opitz SyndromeCompletedNCT00272844Phase 1, Phase 2
20Prenatal Screening For Smith-Lemli-Opitz SyndromeCompletedNCT00070850Phase 2
21Simvastatin Therapy in Smith-Lemli-Opitz SyndromeCompletedNCT00064792Phase 2
22Furlow Palatoplasty With Tensor TenopexyRecruitingNCT01535131Phase 2
23Improvement of the Appearance of Cleft Lip Scars Using BotoxRecruitingNCT02247193Phase 1, Phase 2
24Ambrisentan in Single VentricleRecruitingNCT02080637Phase 2
25IV Acetaminophen in Children Undergoing PalatoplastyWithdrawnNCT01760330Phase 2
26The Use of Self Inflating Tissue Expanders In The Treatment Of Alveolar CleftActive, not recruitingNCT03010345Phase 1
27An Investigation for the Optimal Timing of a Cleft Palate RepairUnknown statusNCT00779961Early Phase 1
28FaceBase BiorepositoryUnknown statusNCT01252264
29Oxygen Insuflation and ArterialDesaturation During Tracheal Intubation in ChildrenUnknown statusNCT01664234
303D Imaging of Hard and Soft Tissue in Orthognathic SurgeryUnknown statusNCT00285714
31Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate PatientsUnknown statusNCT01932164
32SLOS: The Effect of Simvastatin in Patients Receiving Cholesterol SupplementationUnknown statusNCT01434745
33Sterol and Isoprenoid Disease Research Consortium: Smith-Lemli-Opitz SyndromeUnknown statusNCT01356420
34Alveolar Bone Grafting Outcome Between Patient With and Without Orthodontic TreatmentUnknown statusNCT02454998
35One-Piece Le Fort I Osteotomy Versus Segmental Le Fort I OsteotomyUnknown statusNCT01871623
36Osteogenesis and Dental Eruption Through Electrical StimuliUnknown statusNCT00975208
37IAN Injury After BSSO in Oral CleftsUnknown statusNCT01875965
38Comparison of Two Nasoalveolar Molding Techniques in Complete Unilateral Cleft Lip PatientUnknown statusNCT01883726
39Functional Nasal Surgery at the Time of Le Fort I Osteotomy: A Prospective, Single-blind, Randomized TrialUnknown statusNCT01883687
40Sleep and Behavior in Children With Cleft PalateCompletedNCT01046591
41Retrospective Study on the Outcome of Cleft Palate Repair: Comparing US Surgical and Ethicon Suture MaterialsCompletedNCT00584272
42Efficacy of Oral Versus Intravenous Acetaminophen for Primary Pediatric Cleft Palate RepairCompletedNCT01500109
43Relational Development in Children With Cleft Lips and Palates: Influence of the Waiting Period Prior to the First Surgical Intervention and the Parents' Psychological Perception of the AbnormalityCompletedNCT00993993
44Using of Acellular Dermal Matrix in Cleft Palatal Fistula and Compare With Use of Conchal CartolageCompletedNCT03170505
45Postoperative Complications After Cleft Palate Closure in Patients With Pierre Robin Sequence: Operative ConsiderationsCompletedNCT02658318
46Pilot Study Evaluating Characteristic Closure Patterns of the Normal Velopharyngeal PortalCompletedNCT00773994
47Tympanometric Analysis in Cleft PalateCompletedNCT01820689
48Primary Palatoplasty in Pediatric Patients - A Retrospective Review of Surgical OutcomesCompletedNCT01380171
49Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate PatientsCompletedNCT02329509
50Svangerskap, Arv, og Miljo (Pregnancy, Heredity and Environment)CompletedNCT00340977

Search NIH Clinical Center for Cleft Palate, Isolated


Cochrane evidence based reviews: cleft palate

Genetic Tests for Cleft Palate, Isolated

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Genetic tests related to Cleft Palate, Isolated:

id Genetic test Affiliating Genes
1 Cleft Palate, Isolated27 24
2 Cleft Palate27

Anatomical Context for Cleft Palate, Isolated

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Publications for Cleft Palate, Isolated

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Variations for Cleft Palate, Isolated

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Copy number variations for Cleft Palate, Isolated from CNVD:

6
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
143412104640034651237832Deletioncleft palate
2161497221906280919791607Deletioncleft palate
3161606221941203319790830Duplicationcleft palate

Expression for genes affiliated with Cleft Palate, Isolated

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Search GEO for disease gene expression data for Cleft Palate, Isolated.

Pathways for genes affiliated with Cleft Palate, Isolated

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GO Terms for genes affiliated with Cleft Palate, Isolated

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Cellular components related to Cleft Palate, Isolated according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1collagen type XI trimerGO:000559210.6COL11A1, COL11A2
2collagen trimerGO:000558110.4COL11A1, COL11A2, COL2A1
3endoplasmic reticulum lumenGO:000578810.2BMP4, COL11A1, COL11A2, COL2A1
4extracellular regionGO:00055767.8BMP4, COL11A1, COL11A2, COL2A1, FGFR1, FGFR2

Biological processes related to Cleft Palate, Isolated according to GeneCards Suite gene sharing:

(show top 50)    (show all 68)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225510.9MSX1, UBB
2BMP signaling pathway involved in heart developmentGO:006131210.9BMP4, MSX1
3epithelial to mesenchymal transition involved in endocardial cushion formationGO:000319810.9BMP4, MSX1
4keratinocyte proliferationGO:004361610.8IRF6, TP63
5positive regulation of SMAD protein import into nucleusGO:006039110.8BMP4, TGFB3
6embryonic skeletal joint morphogenesisGO:006027210.8BMP4, COL2A1
7embryonic organ morphogenesisGO:004856210.8FGFR2, FOXE1
8cloacal septationGO:006019710.8BMP4, TP63
9branching involved in prostate gland morphogenesisGO:006044210.7BMP4, FGFR2
10bud elongation involved in lung branchingGO:006044910.7BMP4, FGFR2
11membranous septum morphogenesisGO:000314910.7BMP4, FGFR2
12mesodermal cell differentiationGO:004833310.7BMP4, FGFR2
13limb bud formationGO:006017410.7COL2A1, FGFR2
14BMP signaling pathwayGO:003050910.7BMP4, MSX1, TGFB3
15organ inductionGO:000175910.7BMP4, FGFR1
16branching involved in salivary gland morphogenesisGO:006044510.7FGFR1, FGFR2
17fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex developmentGO:003560710.6FGFR1, FGFR2
18lung-associated mesenchyme developmentGO:006048410.6FGFR1, FGFR2
19mesenchymal cell differentiationGO:004876210.6FGFR1, FGFR2
20prostate gland morphogenesisGO:006051210.6BMP4, FGFR2
21regulation of branching involved in prostate gland morphogenesisGO:006068710.6BMP4, FGFR2
22regulation of cell fate commitmentGO:001045310.6BMP4, FGFR2
23salivary gland morphogenesisGO:000743510.6FGFR1, TGFB3
24soft palate developmentGO:006002310.6COL11A2, FOXE1
25orbitofrontal cortex developmentGO:002176910.6FGFR1, FGFR2
26positive regulation of phospholipase activityGO:001051810.6FGFR1, FGFR2
27regulation of morphogenesis of a branching structureGO:006068810.6BMP4, FGFR2
28regulation of smooth muscle cell differentiationGO:005115010.6BMP4, FGFR2
29proteoglycan metabolic processGO:000602910.6COL11A1, COL2A1
30odontogenesis of dentin-containing toothGO:004247510.6BMP4, MSX1, TP63
31smooth muscle tissue developmentGO:004874510.6BMP4, TP63
32lung alveolus developmentGO:004828610.5BMP4, FGFR2, TGFB3
33hair follicle morphogenesisGO:003106910.5FGFR2, FOXE1, TP63
34bone developmentGO:006034810.5BMP4, COL2A1, FGFR2
35fibroblast growth factor receptor signaling pathwayGO:000854310.5FGFR1, FGFR2, UBB
36squamous basal epithelial stem cell differentiation involved in prostate gland acinus developmentGO:006052910.5FGFR2, TP63
37midbrain developmentGO:003090110.5FGFR1, FGFR2, MSX1
38embryonic cranial skeleton morphogenesisGO:004870110.5BMP4, FGFR2, FOXC2
39collagen catabolic processGO:003057410.4COL11A1, COL11A2, COL2A1
40lung developmentGO:003032410.4BMP4, FGFR1, FGFR2
41ventricular zone neuroblast divisionGO:002184710.4FGFR1, FGFR2
42odontogenesisGO:004247610.3BMP4, FGFR2, MSX1, TGFB3
43positive regulation of mesenchymal cell proliferationGO:000205310.3FGFR1, FGFR2, TP63
44positive regulation of cell divisionGO:005178110.3FGFR2, TGFA, TGFB3
45positive regulation of epithelial cell proliferationGO:005067910.3BMP4, FGFR2, TGFA
46in utero embryonic developmentGO:000170110.3FGFR1, FGFR2, MSX1, TGFB3
47embryonic limb morphogenesisGO:003032610.3BMP4, FGFR1, MSX1, TP63
48heart morphogenesisGO:000300710.2COL11A1, COL2A1, FOXC2, MSX1
49chondrocyte differentiationGO:000206210.2BMP4, COL11A2, COL2A1, FGFR1
50negative regulation of transcription, DNA-templatedGO:004589210.2BMP4, FOXE1, MSX1, TBX22, TP63

Molecular functions related to Cleft Palate, Isolated according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrix structural constituent conferring tensile strengthGO:003002010.1COL11A2, COL2A1
2extracellular matrix structural constituentGO:00052019.9COL11A1, COL11A2, COL2A1
3fibroblast growth factor-activated receptor activityGO:00050079.9FGFR1, FGFR2

Sources for Cleft Palate, Isolated

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet