MCID: CLF027
MIFTS: 56

Cleft Palate, Isolated malady

Categories: Genetic diseases (common), Oral diseases, Neuronal diseases, Mental diseases

Aliases & Classifications for Cleft Palate, Isolated

About this section

Aliases & Descriptions for Cleft Palate, Isolated:

Name: Cleft Palate, Isolated 51 24 67
Cleft Palate 11 26 49 38 13 67
Cleft Palate Isolated 69 26
Uranostaphyloschisis 11 67
Cleft Palate Isolated with Mental Retardation 69
 
Isolated Cleft Palate 11
Palatoschisis 11
Cleft Velum 11
Cpi 69
Cp 69

Characteristics:

HPO:

63
cleft palate, isolated:
Inheritance: autosomal dominant inheritance

Classifications:



Summaries for Cleft Palate, Isolated

About this section
UniProtKB/Swiss-Prot:69 Cleft palate isolated: A congenital fissure of the soft and/or hard palate, due to faulty fusion. Isolated cleft palate is not associated with cleft lips. Some patients may manifest other craniofacial dysmorphic features, mental retardation, and osteoporosis.

MalaCards based summary: Cleft Palate, Isolated, also known as cleft palate, is related to cleft lip +/- cleft palate and cleft palate with ankyloglossia, and has symptoms including non-midline cleft lip, cleft palate and gingival overgrowth. An important gene associated with Cleft Palate, Isolated is UBB (Ubiquitin B), and among its related pathways are Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include bone, and related mouse phenotypes are no phenotypic analysis and muscle.

Disease Ontology:11 An orofacial cleft characterized by a fissure of the soft and/or hard palate, due to faulty fusion of the two plates of the skull that form the hard palate.

OMIM:51 Cleft palate as an isolated malformation behaves as an entity distinct from cleft lip with or without cleft palate (see... (119540) more...

Related Diseases for Cleft Palate, Isolated

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Diseases related to Cleft Palate, Isolated via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 115)
idRelated DiseaseScoreTop Affiliating Genes
1cleft lip +/- cleft palate12.3
2cleft palate with ankyloglossia12.3
3microtia, hearing impairment, and cleft palate12.2
4cleft palate, psychomotor retardation, and distinctive facial features12.1
5submucosal cleft palate12.1
6cleft palate, cardiac defect, genital anomalies, and ectrodactyly12.0
7syngnathia cleft palate12.0
8omphalocele-cleft palate syndrome, lethal12.0
9cleft palate x-linked12.0
10dominant cleft palate11.9
11ankyloblepharon filiforme adnatum and cleft palate11.9
12acromegaloid features, overgrowth, cleft palate, and hernia11.9
13hydronephrosis, congenital, with cleft palate, characteristic facies, hypotonia, and mental retardation11.9
14cleft palate, midfacial hypoplasia, triangular facies, and sensorineural hearing loss11.9
15palant cleft palate syndrome11.9
16native american myopathy11.9
17spondyloepiphyseal dysplasia with coronal craniosynostosis, cataracts, cleft palate, and mental retardation11.8
18cleft palate, deafness, and oligodontia11.8
19cleft palate short stature vertebral anomalies11.8
20dysmorphism cleft palate loose skin11.8
21hypotelorism cleft palate hypospadias11.8
22anophthalmia cleft palate micrognathia11.8
23cleft palate cardiac defect ectrodactyly11.8
24cleft palate colobomata radial synostosis deafness11.8
25cleft palate heart disease polydactyly absent tibia11.8
26cleft palate stapes fixation oligodontia11.8
27craniosynostosis arthrogryposis cleft palate11.8
28cystic hygroma lethal cleft palate11.8
29hirschsprung microcephaly cleft palate11.8
30hydrocephalus-cleft palate-joint contractures syndrome11.8
31mesomelic dwarfism cleft palate camptodactyly11.8
32short limbs subluxed knees cleft palate11.8
33short stature monodactylous ectrodactyly cleft palate11.8
34microcephaly-cleft palate syndrome11.8
35blepharoptosis-cleft palate-ectrodactyly-dental anomalies syndrome11.8
36auricular abnormalities-cleft lip with or without cleft palate-ocular abnormalities syndrome11.8
37cleft soft palate11.8
38cleft lip/palate11.7
39syngnathia11.7
40orofacial cleft 1111.7
41mandibulofacial dysostosis, guion-almeida type11.7
42pierre robin syndrome11.6
43abruzzo-erickson syndrome11.6
44bamforth-lazarus syndrome11.6
45arthrogryposis, distal, type 311.6
46cleft lip/palate-ectodermal dysplasia syndrome11.6
47isolated pierre robin sequence11.6
48rapp-hodgkin syndrome11.5
49orofacial cleft 611.5
50orofacial cleft 511.5

Graphical network of the top 20 diseases related to Cleft Palate, Isolated:



Diseases related to cleft palate, isolated

Symptoms for Cleft Palate, Isolated

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Symptoms by clinical synopsis from OMIM:

119540

Clinical features from OMIM:

119540

Human phenotypes related to Cleft Palate, Isolated:

 63 (show all 8)
id Description HPO Frequency HPO Source Accession
1 non-midline cleft lip63 occasional (7.5%) HP:0100335
2 cleft palate63 HP:0000175
3 gingival overgrowth63 HP:0000212
4 micrognathia63 HP:0000347
5 seizures63 HP:0001250
6 intellectual disability, profound63 HP:0002187
7 anterior open-bite malocclusion63 HP:0009102
8 overbite63 HP:0011094

UMLS symptoms related to Cleft Palate, Isolated:


seizures

Drugs & Therapeutics for Cleft Palate, Isolated

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Drugs for Cleft Palate, Isolated (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 84)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Tranexamic AcidapprovedPhase 42571197-18-85526
Synonyms:
08455_FLUKA
1197-17-7
1197-18-8
1ceb
3-14-00-00868 (Beilstein Handbook Reference)
4-(Aminomethyl)-Cyclohexanecarboxylic Acid
4-(Aminomethyl)cyclohexanecarboxylic acid
4-(aminomethyl)cyclohexane-1-carboxylic acid
857653_ALDRICH
A0236
AB00052260
AB1003647
AC-4687
AC1L1KJH
AC1Q50F3
AC1Q546D
AC1Q5U04
ALBB-006013
AMCA
AMCHA
AMH
AR-1F6595
Acide tranexamique
Acide tranexamique [INN-French]
Acido tranexamico
Acido tranexamico [INN-Spanish]
Acidum tranexamicum
Acidum tranexamicum [INN-Latin]
Amikapron
Amstat
Anvitoff
BAY 3517
BPBio1_000069
BRN 2207452
BSPBio_000061
BSPBio_002837
CAS-1197-18-8
CHEBI:48669
CHEMBL292500
CHEMBL877
CID5526
CL 65336
CL-65336
Carxamin
Cyclocapron
Cyklokapron
Cyklokapron (TN)
D01136
DB00302
DV 79
DV-79
DV79
DivK1c_000655
EINECS 214-818-2
Emorhalt
Exacyl
Frenolyse
HMS1568D03
HMS1921F08
HMS2092P03
HMS502A17
Hexapromin
Hexatron
I04-0993
IDI1_000655
KABI 2161
KBio1_000655
KBio2_001871
KBio2_004439
KBio2_007007
KBio3_002337
KBioGR_000511
 
KBioSS_001871
LS-56611
LS-56612
LT00159441
Mastop
MolPort-001-792-390
MolPort-002-512-008
NCGC00016569-01
NCGC00016569-02
NCGC00016569-03
NCGC00094944-01
NCGC00094944-02
NINDS_000655
NSC 291305
NSC291305
Oprea1_786414
Prestwick0_000171
Prestwick1_000171
Prestwick2_000171
Prestwick3_000171
Prestwick_476
RP 18,429
Rikavarin
Rikavarin (TN)
Rikavarin-S
SPBio_000689
SPBio_001982
SPECTRUM1502026
STK503668
STOCK1N-16183
Spectrum2_000655
Spectrum3_001189
Spectrum4_000046
Spectrum5_001258
Spectrum_001391
Spiramin
Tamcha
Tranex
Tranexamate
Tranexamic acid (JP15/USAN/INN)
Tranexamic acid [USAN:INN:BAN:JAN]
Tranexamic acid cis-form
Tranexamsaeure
Tranexan
Tranexmic acid
Tranhexamic acid
Trans AMCHA
Trans-1-(Aminomethyl)cyclohexane-4-carboxylic acid
Trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid
Trans-p-(Aminomethyl)cyclohexanecarboxylic
Transamin
Transamin (TN)
Transamlon
Trasamlon
UNII-6T84R30KC1
Ugurol
WLN: L6TJ AVQ D1Z -T
cis-4-(Aminomethyl)cyclohexanecarboxylic acid
cis-4-Aminomethylcyclohexane-1-carboxylic acid
cis-AMCHA
t-AMCHA
tranexamic acid
tranexmic acid
trans-1-Aminomethylcyclohexane-4-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-1-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-carboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid ester
trans-4-Aminomethylcyclohexane-1-carboxylic acid
trans-4-aminomethylcyclohexane-1-carboxylic acid
trans-Amcha
trans-Tranexamic acid
trans-p-(Aminomethyl)cyclohexanecarboxylic acid
2
Guaifenesinapproved, vet_approvedPhase 461693-14-13516
Synonyms:
3-(2-Methoxyphenoxy)-1,2-propanediol
3-(O-Methoxyphenoxy)-1,2-propanediol
3-(O-Methoxyphenoxy)-propanediol-1,2
3-O-Methoxyphenoxypropane 1:2-diol
Actifed C
Aeronesin
Amonidren
Amonidrin
Aresol
Benylin-E
Bronchol
Glycerin ether
Glycerin guaiacolate
Glycero-guaiacol ether
Glycerol a-(2-methoxyphenyl) ether
Glycerol a-(O-methoxyphenyl)ether
Glycerol a-guaiacyl ether
Glycerol a-guiacyl ether
Glycerol a-monoguaiacol ether
Glycerol guaiacolate
Glycerol mono(2-methoxyphenyl) ether
Glycerol-a-guajakolether
Glycerol-alpha-guajakolether
Glyceryl guaiacol
Glyceryl guaiacol ether
Glyceryl guaiacolate
Glyceryl guaiacolate ether
Glyceryl guaiacyl ether
Glyceryl guaicolate
Glyceryl guiacolate
 
Glycerylguaiacol
Guaiacol glycerol ether
Guaiacol glyceryl ether
Guaiacolglicerinetere
Guaiacuran
Guaiacurane
Guaiacyl glyceryl ether
Guaiamar
Guaianesin
Guaicol glycerine ether
Guaicol glyceryl ether
Guaifenesin
Guaifenesine
Guaiphenesin
Guaiphenesine
Guaiphesin
Hustosil
Methoxypropanediol
Methphenoxydiol
Metossipropandiolo
O-Methoxyphenyl glyceryl ether
Organidin NR
Pneumomist
Propanosedyl
Reduton
Robitussin
a-Glyceryl guaiacol ether
a-Glyceryl guaiacolate ether
alpha-Glyceryl guaiacol ether
alpha-Glyceryl guaiacolate ether
guaiphenesin
p-Cresyl acetate
3
Codeineapproved, illicitPhase 47476-57-35284371
Synonyms:
(-)-Codeine
(5alpha,6alpha)-17-methyl-3-(methyloxy)-7,8-didehydro-4,5-epoxymorphinan-6-ol
(5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
(5α,6α)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
(6alpha,13alpha)-3-methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6-ol
(−)-Codeine
3-Methylmorphin
3-methoxy-17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-6alpha-ol
3-methylmorphine
3-o-methylmorphine monohydrate
41444-62-6 (PO4)
7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methylmorphinan-6-alpha-ol
7,8-didehydro-4,5-ep oxy-3-methoxy-17-methylmorphinan-6-ol
7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-(5alpha, 6alpha)-morphinan 6-ol
7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methylmorphinan-6alpha-ol
7,8-didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol
76-57-3
AC-11114
AC1Q4DTD
Actacode
Ardinex
C06174
C1653_FLUKA
C1653_SIGMA
C5901_FLUKA
C5901_SIGMA
CCRIS 7555
CHEBI:16714
CHEMBL485
CID5284371
CODEINE (SEE ALSO: CODEINE PHOSPHATE (CAS 52-28-8))
CODEINE BASE
Calcidrine
Codalgin Forte Codate
Codein
Codeine
Codeine (anhydrous)
Codeine [BAN]
Codeine anhydrous
Codeine solution
 
Codeinum
Codeína
Codicept
Coducept
Codéine
DB00318
EINECS 200-969-1
HSDB 3043
Isocodeine
L-Codeine
LS-1695
Methylmorphine
MolPort-002-506-913
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5-alpha,6-alpha)- (9CI)
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)- (9CI)
Morphinan-6alpha-ol, 7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methyl- (8CI)
Morphine 3-methyl ether
Morphine monomethyl ether
Morphine-3-methyl ester
Morphine-3-methyl ether
N-Methylmorphine
N-methyl norcodine
N-methylnorcodeine
Norcodeine, N-Methyl
Norcodeine, N-methyl
Norcodine, N-Methyl
Norcodine, N-methyl
Novahistine DH
O(3)-methylmorphine
O3-Methylmorphine
Robitussin AC
STOCK1N-42851
codeina
codeine
codeinum
l-Codeine
metilmorfina
morphine 3-methyl ether
morphine monomethy l ether
morphine monomethyl ether
morphine-3-methyl ether
nchembio.317-comp2
4
Amoxicillinapproved, vet_approvedPhase 444126787-78-033613, 2171
Synonyms:
(-)-6-(2-Amino-2-(P-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo-(3.2.0)heptane-2-carboxylic acid
(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
26787-78-0
33911-69-2
34642-77-8 (mono-hydrochloride salt)
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-(p-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-, D- (8CI)
6-(D-(-)-alpha-Amino-p-hydroxyphenylacetamido)penicillanic acid
6-(D-(-)-p-Hydroxy-alpha-aminobenzyl)penicillin
6-(P-Hydroxy-alpha-aminophenylacetamido)penicillanic acid
6-(a-Amino-4-hydroxyphenylacetamido)penicillanic acid
6-(p-Hydroxy-alpha-aminophenylacetamido)penicillanic acid
6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid
6-[[Amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 9CI
61336-70-7 (TRIHYDRATE)
6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carbonyl
6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid
71447-36-4
81030-75-3
AC-12263
AC1L1PY2
AMC
AMOXICILLIN CRYSTALLINE
AMOXICILLIN PEDIATRIC
AMPC
AUGMENTIN '125'
AUGMENTIN '200'
AUGMENTIN '250'
AUGMENTIN '400'
AUGMENTIN '500'
AUGMENTIN '875'
AUGMENTIN ES-600
AX
Actimoxi
Almodan
Ambap26787-78-0
Amix
Amoclen
Amolin
Amopen
Amopenixin
Amoram
Amox
Amox 250 Cap 250mg
Amox 500 Cap 500mg
Amox S 125 Sus 125mg/5ml
Amox S 250 Sus 250mg/5ml
Amoxi
Amoxi-Mast
Amoxi-mast
Amoxibiotic
Amoxicaps
Amoxicilina
Amoxicilina [INN-Spanish]
Amoxicillin (INN)
Amoxicillin (TN)
Amoxicillin (anhydrous)
Amoxicillin (inn)
Amoxicillin Trihydrate
Amoxicillin and clavulanate potassium
Amoxicillin anhydrous
Amoxicillin pediatric
Amoxicillin trihydrate
Amoxicillin(usan)
Amoxicilline
Amoxicilline [INN-French]
Amoxicilline [INN]
Amoxicilline [inn]
Amoxicillinum
Amoxicillinum [INN-Latin]
Amoxid
Amoxiden
Amoxil
Amoxivet
Amoxycillin
Amoxycillin Trihydrate
Amoxycillin trihydrate
Amoxycillin, BAN
Amoxymed
Amrit
Anemolin
Apo-Amoxi
Apo-Amoxi Cap 250mg
Apo-Amoxi Cap 500mg
Apo-Amoxi Pwr for Susp 125mg/5ml
Apo-Amoxi Pwr for Susp 250mg/5ml
Apo-amoxi
Apo-amoxi sugar free
Aspenil
BL-P 1410
BLP 1410
BPBio1_000499
BRD-K55044200-001-03-9
BRL 2333
BRL-2333
BSPBio_000453
 
Biomox
Bristamox
C06827
CHEBI:2676
CHEBI:53712
CHEMBL1082
CID33613
CPD000058707
Cemoxin
Clamoxyl
Clamoxyl (SKB)
D-(-)-alpha-Amino-p-hydroxybenzyl penicillin
D-(-)-alpha-Amino-p-hydroxybenzylpenicillin
D-(alpha-Amino-p-hydroxybenzyl)penicillin
D-2-Amino-2-(4-hydroxyphenyl)acetamidopenicillanic acid
D-Amoxicillin
D07452
DB01060
Delacillin
DisperMox
Dispermox
EINECS 248-003-8
Efpenix
Flemoxin
Galenamox
Gen-Amoxicillin 250mg
Gen-Amoxicillin 500mg
HMS1569G15
HSDB 3204
Hiconcil
Histocillin
Hydroxyampicillin
Ibiamox
Imacillin
LS-149721
Lamoxy
Larotid
MLS000028632
MLS002222248
Metafarma capsules
Metifarma capsules
MolPort-003-981-182
MolPort-005-933-687
Moxacin
Moxal
Moxatag
NCGC00179554-01
NSC 277174
NSC277174
Novamoxin Cap 250mg
Novamoxin Cap 500mg
Novamoxin Sus 125mg/5ml
Novamoxin Sus 250mg/5ml
Nu-Amoxi Cap 250mg
Nu-Amoxi Cap 500mg
Nu-Amoxi Sus 125/5ml
Nu-Amoxi Sus 250mg/5ml
Ospamox
P-Hydroxyampicillin
PHL-amoxicillin
PMS-amoxicillin
Pamoxicillin
Piramox
Polymox
Prestwick0_000357
Prestwick1_000357
Prestwick2_000357
Prestwick3_000357
Prestwick_713
Prevpac
Pro Amox Pwr for Oral Susp 125mg/5ml
Pro Amox-250 Cap 250mg
Pro Amox-500 Cap 500mg
Pro-Amox-250 Orl Sus 250mg/5ml
R-Hydroxyampicillin
Rimoxallin
Ro 10-8756
Robamox
SAM002264592
SMR000058707
SPBio_002374
Sauracillin
Sawamox PM
Sumox
Tolodina
Trimox
Unicillin
Utimox
Vetramox
Wymox
Zimox
alpha-Amino-p-hydroxybenzylpenicillin
alpha-amino-P-Hydroxybenzylpenicillin
amoxicillanyl
amoxicillin
p-Hydroxyampicillin
α-amino-p-hydroxybenzylpenicillin
5
Dexmedetomidineapproved, vet_approvedPhase 454076631-46-4, 113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
 
Dexdor (T)
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex (TN)
Tocris-2023
ZINC04632106
6Anti-Bacterial AgentsPhase 4, Phase 210884
7Antibiotics, AntitubercularPhase 4, Phase 26972
8AnalgesicsPhase 4, Phase 3, Phase 211287
9Anti-Infective AgentsPhase 4, Phase 221402
10HemostaticsPhase 41359
11Antitubercular AgentsPhase 4, Phase 21272
12CoagulantsPhase 41428
13Central Nervous System DepressantsPhase 4, Phase 2, Phase 312806
14Antitussive AgentsPhase 4520
15Analgesics, OpioidPhase 43091
16Analgesics, Non-NarcoticPhase 4, Phase 3, Phase 26260
17Chlorpheniramine, phenylpropanolamine drug combinationPhase 4616
18Antifibrinolytic AgentsPhase 4459
19NarcoticsPhase 43486
20Respiratory System AgentsPhase 44818
21Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 3, Phase 122776
22Neurotransmitter AgentsPhase 4, Phase 1, Phase 217734
23Fibrin Tissue AdhesivePhase 4145
24Hypnotics and SedativesPhase 42485
25Adrenergic AgonistsPhase 42877
26Adrenergic alpha-AgonistsPhase 41625
27Adrenergic AgentsPhase 45140
28Adrenergic alpha-2 Receptor AgonistsPhase 4911
29
Bupivacaineapproved, investigationalPhase 2, Phase 311312180-92-9, 38396-39-32474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
(±)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
 
DepoBupivacaine
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
racemic bupivacaine
30
LevobupivacaineapprovedPhase 2, Phase 316527262-47-192253
Synonyms:
(-)-Bupivacaine
(-)-bupivacaine
(2S)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(S)-1-Butyl-2',6'-pipecoloxylidide
(S)-Bupivacaine
(S)-bupivacaine
27262-47-1
27262-48-2
AC1L3NQM
BIDD:GT0471
C07887
C18H28N2O
CAS-18010-40-7
CHEBI:6149
CID92253
D08116
 
DB01002
L(-)-Bupivacaine
L-(-)-1-Butyl-2',6'-pipecoloxylidide
L-(-)-Bupivacaine
L-(-)-bupivacaine
LS-109843
LS-187025
LS-187789
Levobupivacaine
Levobupivacaine (INN)
Levobupivacaine [INN:BAN]
Levobupivacaine hydrochloride
MolPort-004-959-713
NCGC00016733-01
NCGC00159482-02
Novabupi
Novabupi (TN)
31
Epinephrineapproved, vet_approvedPhase 393351-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
32
KetorolacapprovedPhase 330474103-06-3, 66635-83-43826
Synonyms:
(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
(+-)-Ketorolac
(+-)-isomer
(.+/-.)-2,3-Dihydro-5-benzoyl-1H-pyrrolizine-1-carboxylic acid
1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro
5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
5-Benzoyl-1,2-dihydro-3H-pyrrolo(1,2a)pyrrole-1-carboxylic acid
5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
66635-83-4
74103-06-3
AB00053682
AC-545
AC1L1GSW
BRD-A40639672-234-05-7
C07062
CHEBI:105080
CHEMBL469
CID3826
D020910
D08104
DB00465
 
I14-2832
Ketoralac
Ketorolac
Ketorolac (INN)
Ketorolac Tromethamine
Ketorolac [INN:BAN]
Ketorolaco
Ketorolaco [Spanish]
Ketorolacum
Ketorolacum [Latin]
Kétorolac
LS-139094
Macril
MolPort-005-933-093
NCGC00185990-01
RS 37619
RS-37619
SBB067312
STL018674
Toradol (TN)
UNII-YZI5105V0L
ketorolac
rac-Ketorolac
33
Folic Acidapproved, nutraceutical, vet_approvedPhase 3427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
34VitaminsPhase 35095
35Trace ElementsPhase 35802
36HematinicsPhase 31630
37MicronutrientsPhase 35802
38Vitamin B ComplexPhase 34229
39Cyclooxygenase InhibitorsPhase 32778
40RacepinephrinePhase 3933
41Epinephryl boratePhase 3933
42Ketorolac TromethaminePhase 3304
43Pharmaceutical SolutionsPhase 3, Phase 27793
44Anti-Inflammatory AgentsPhase 310355
45Antirheumatic AgentsPhase 310627
46Anesthetics, LocalPhase 2, Phase 33272
47AnestheticsPhase 2, Phase 3, Phase 19001
48Anti-Inflammatory Agents, Non-SteroidalPhase 34295
49FolateNutraceuticalPhase 34279
50Vitamin B9NutraceuticalPhase 34279

Interventional clinical trials:

(show top 50)    (show all 83)
idNameStatusNCT IDPhase
1Double Blind Randomized Study Into the Efficacy of Codeine Phosphate Analgesia After Cleft Palate Repair in InfantsCompletedNCT00386269Phase 4
2Acid Tranexamic Effectiveness in Reducing the Intraoperative Bleeding in PalatoplastyCompletedNCT02422056Phase 4
3The Role of Antibiotic Prophylaxis in Cleft Palate and Velopharyngeal Insufficiency RepairRecruitingNCT02688634Phase 4
4The Use of Fibrin Sealant to Reduce Post Operative Pain in Cleft Palate SurgeryRecruitingNCT02953145Phase 4
5Dexmedetomidine vs Placebo for Pediatric Cleft Palate RepairNot yet recruitingNCT02915042Phase 4
6Oral Cleft Prevention ProgramUnknown statusNCT00397917Phase 3
7Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate SurgeryCompletedNCT02923869Phase 2, Phase 3
8Oral Cleft Prevention Trial in BrazilCompletedNCT00098319Phase 3
9A Comparison of Bupivacaine and Ketorolac for Postoperative Analgesia After Iliac Crest Bone HarvestingCompletedNCT00405262Phase 3
10Assessing the Results of Lip Surgery in Patients With Cleft Lip and PalateCompletedNCT00070811Phase 2, Phase 3
11Phase II Study of Dietary Cholesterol for Smith-Lemli-Opitz SyndromeUnknown statusNCT00004347Phase 2
12Preoperative Antibiotics StudyCompletedNCT00760006Phase 2
13Cleft Palate Surgery and Speech DevelopmentCompletedNCT00004639Phase 2
14Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?CompletedNCT00930124Phase 2
15Cell Therapy for Craniofacial Bone DefectsCompletedNCT01616953Phase 1, Phase 2
16Does Use of Rigid Fixation After Removing Distraction Osteogenesis Device Reduce the Relapse?CompletedNCT02350803Phase 2
17Short-term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz SyndromeCompletedNCT00114634Phase 2
18Treatment of the Cholesterol Defect in Smith-Lemli-Opitz SyndromeCompletedNCT00272844Phase 1, Phase 2
19Prenatal Screening For Smith-Lemli-Opitz SyndromeCompletedNCT00070850Phase 2
20Simvastatin Therapy in Smith-Lemli-Opitz SyndromeCompletedNCT00064792Phase 2
21Furlow Palatoplasty With Tensor TenopexyRecruitingNCT01535131Phase 2
22Improvement of the Appearance of Cleft Lip Scars Using BotoxRecruitingNCT02247193Phase 1, Phase 2
23Ambrisentan in Single VentricleRecruitingNCT02080637Phase 2
24IV Acetaminophen in Children Undergoing PalatoplastyWithdrawnNCT01760330Phase 2
25The Use of Self Inflating Tissue Expanders In The Treatment Of Alveolar CleftActive, not recruitingNCT03010345Phase 1
26An Investigation for the Optimal Timing of a Cleft Palate RepairUnknown statusNCT00779961Early Phase 1
27FaceBase BiorepositoryUnknown statusNCT01252264
28Oxygen Insuflation and ArterialDesaturation During Tracheal Intubation in ChildrenUnknown statusNCT01664234
293D Imaging of Hard and Soft Tissue in Orthognathic SurgeryUnknown statusNCT00285714
30Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate PatientsUnknown statusNCT01932164
31SLOS: The Effect of Simvastatin in Patients Receiving Cholesterol SupplementationUnknown statusNCT01434745
32Sterol and Isoprenoid Disease Research Consortium: Smith-Lemli-Opitz SyndromeUnknown statusNCT01356420
33One-Piece Le Fort I Osteotomy Versus Segmental Le Fort I OsteotomyUnknown statusNCT01871623
34Osteogenesis and Dental Eruption Through Electrical StimuliUnknown statusNCT00975208
35Comparison of Two Nasoalveolar Molding Techniques in Complete Unilateral Cleft Lip PatientUnknown statusNCT01883726
36Sleep and Behavior in Children With Cleft PalateCompletedNCT01046591
37Retrospective Study on the Outcome of Cleft Palate Repair: Comparing US Surgical and Ethicon Suture MaterialsCompletedNCT00584272
38Efficacy of Oral Versus Intravenous Acetaminophen for Primary Pediatric Cleft Palate RepairCompletedNCT01500109
39Relational Development in Children With Cleft Lips and Palates: Influence of the Waiting Period Prior to the First Surgical Intervention and the Parents' Psychological Perception of the AbnormalityCompletedNCT00993993
40Postoperative Complications After Cleft Palate Closure in Patients With Pierre Robin Sequence: Operative ConsiderationsCompletedNCT02658318
41Pilot Study Evaluating Characteristic Closure Patterns of the Normal Velopharyngeal PortalCompletedNCT00773994
42Tympanometric Analysis in Cleft PalateCompletedNCT01820689
43Primary Palatoplasty in Pediatric Patients - A Retrospective Review of Surgical OutcomesCompletedNCT01380171
44Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate PatientsCompletedNCT02329509
45Svangerskap, Arv, og Miljo (Pregnancy, Heredity and Environment)CompletedNCT00340977
46Articulation and Phonology in Children With Unilateral Cleft Lip and PalateCompletedNCT00829101
47Systematic Pediatric Care for Oral Clefts - South AmericaCompletedNCT00097149
48A Study to Examine the Relationship Between Sleep Apnea and Cleft Lip/PalateCompletedNCT00156442
49Effect Of Combination of Morphine+Fentanyl on Emergence Delirium in Patients of Cleft Lip and Palate RepairCompletedNCT03010540
50Velocardiofacial (VCFS; 22q11.2; DiGeorge) Syndrome StudyCompletedNCT00105274

Search NIH Clinical Center for Cleft Palate, Isolated


Cochrane evidence based reviews: cleft palate

Genetic Tests for Cleft Palate, Isolated

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Genetic tests related to Cleft Palate, Isolated:

id Genetic test Affiliating Genes
1 Cleft Palate, Isolated26 24
2 Cleft Palate26

Anatomical Context for Cleft Palate, Isolated

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MalaCards organs/tissues related to Cleft Palate, Isolated:

35
Bone

Animal Models for Cleft Palate, Isolated or affiliated genes

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Publications for Cleft Palate, Isolated

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Variations for Cleft Palate, Isolated

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Clinvar genetic disease variations for Cleft Palate, Isolated:

5
id Gene Variation Type Significance SNP ID Assembly Location
1GNB1NM_002074.4(GNB1): c.239T> C (p.Ile80Thr)SNVPathogenicrs752746786GRCh37Chr 1, 1737942: 1737942

Copy number variations for Cleft Palate, Isolated from CNVD:

6
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
143412104640034651237832Deletioncleft palate
2161497221906280919791607Deletioncleft palate
3161606221941203319790830Duplicationcleft palate

Expression for genes affiliated with Cleft Palate, Isolated

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Search GEO for disease gene expression data for Cleft Palate, Isolated.

Pathways for genes affiliated with Cleft Palate, Isolated

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Pathways related to Cleft Palate, Isolated according to GeneCards Suite gene sharing:

(show all 14)
idSuper pathwaysScoreTop Affiliating Genes
19.8BMP4, COL2A1, TGFB3
29.7BMP4, IRF6, MSX1, TP63
39.6FGFR1, TGFB3, TGFBR2
4
Show member pathways
9.3FGFR1, FGFR2, TGFA, TGFB3
59.2BMP4, COL2A1, FGFR1, FGFR2, MSX1
6
Show member pathways
9.2FGFR1, FGFR2, GABRB3, TGFBR2
7
Show member pathways
9.2BMP4, FGFR2, GNB1, TGFB3, TGFBR2
8
Show member pathways
8.8BMP4, FGFR1, FGFR2, TGFA, TGFB3, UBB
9
Show member pathways
8.8BMP4, FGFR1, FGFR2, GNB1, TGFA, TGFB3
108.8BMP4, FGFR1, FGFR2, GNB1, TGFA, TGFB3
11
Show member pathways
8.6BMP4, FGFR1, FGFR2, TGFA, TGFB3, TGFBR2
128.4BMP4, FGFR1, FGFR2, GNB1, TGFA, TGFB3
13
Show member pathways
8.3BMP4, FGFR1, FGFR2, GNB1, TGFA, TGFB3
14
Show member pathways
8.2BMP4, COL11A1, COL2A1, FGFR1, FGFR2, GNB1

GO Terms for genes affiliated with Cleft Palate, Isolated

About this section

Biological processes related to Cleft Palate, Isolated according to GeneCards Suite gene sharing:

(show all 50)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225510.8MSX1, UBB
2embryonic organ morphogenesisGO:004856210.7FGFR2, FOXE1
3BMP signaling pathway involved in heart developmentGO:006131210.7BMP4, MSX1
4squamous basal epithelial stem cell differentiation involved in prostate gland acinus developmentGO:006052910.7FGFR2, TP63
5cloacal septationGO:006019710.6BMP4, TP63
6fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex developmentGO:003560710.6FGFR1, FGFR2
7regulation of cell fate commitmentGO:001045310.6BMP4, FGFR2
8regulation of morphogenesis of a branching structureGO:006068810.6BMP4, FGFR2
9prostate gland morphogenesisGO:006051210.6BMP4, FGFR2
10branching involved in prostate gland morphogenesisGO:006044210.6BMP4, FGFR2
11regulation of smooth muscle cell differentiationGO:005115010.6BMP4, FGFR2
12bud elongation involved in lung branchingGO:006044910.6BMP4, FGFR2
13regulation of branching involved in prostate gland morphogenesisGO:006068710.6BMP4, FGFR2
14lung lobe morphogenesisGO:006046310.5FGFR2, TGFBR2
15common-partner SMAD protein phosphorylationGO:000718210.5BMP4, TGFBR2
16bronchus developmentGO:006043310.5BMP4, TGFBR2
17trachea formationGO:006044010.4BMP4, TGFBR2
18ventricular zone neuroblast divisionGO:002184710.4FGFR1, FGFR2
19lung alveolus developmentGO:004828610.3BMP4, FGFR2, TGFB3
20bone developmentGO:006034810.3BMP4, COL2A1, FGFR2
21hair follicle morphogenesisGO:003106910.3FGFR2, FOXE1, TP63
22chondrocyte differentiationGO:000206210.2BMP4, COL2A1, FGFR1
23ventricular cardiac muscle tissue morphogenesisGO:005501010.2COL11A1, FGFR2, FOXC2
24positive regulation of cell divisionGO:005178110.2FGFR2, TGFA, TGFB3
25odontogenesisGO:004247610.1BMP4, FGFR2, MSX1, TGFB3
26digestive tract developmentGO:004856510.1FGFR2, TGFB3, TGFBR2
27blood vessel developmentGO:000156810.0BMP4, FOXC2, TGFBR2
28midbrain developmentGO:003090110.0FGFR1, FGFR2, MSX1
29collagen fibril organizationGO:003019910.0COL11A1, COL2A1, FOXC2
30embryonic limb morphogenesisGO:00303269.9BMP4, FGFR1, MSX1, TP63
31embryonic skeletal system morphogenesisGO:00487049.9BMP4, COL11A1, FOXC2, SATB2
32heart morphogenesisGO:00030079.9COL11A1, COL2A1, FOXC2, MSX1
33skeletal system morphogenesisGO:00487059.9COL11A1, COL2A1, FGFR1, FGFR2
34orbitofrontal cortex developmentGO:00217699.9FGFR1, FGFR2
35ureteric bud developmentGO:00016579.8BMP4, FGFR1, FGFR2, FOXC2
36Notch signaling pathwayGO:00072199.8FOXC2, TGFBR2, TP63, UBB
37positive regulation of mesenchymal cell proliferationGO:00020539.8FGFR1, FGFR2, TGFBR2, TP63
38embryonic cranial skeleton morphogenesisGO:00487019.8BMP4, FGFR2, FOXC2, TGFBR2
39inner ear morphogenesisGO:00424729.7COL11A1, COL2A1, FGFR1, FGFR2
40cartilage developmentGO:00512169.7COL11A1, COL2A1, MSX1, SATB2, TGFBR2
41lung developmentGO:00303249.7BMP4, FGFR1, FGFR2, TGFBR2
42in utero embryonic developmentGO:00017019.6FGFR1, FGFR2, MSX1, TGFB3, TGFBR2
43sensory perception of soundGO:00076059.6COL11A1, COL2A1, FGFR1, GABRB3
44positive regulation of transcription, DNA-templatedGO:00458939.6BMP4, FOXC2, FOXE1, IRF6, TGFB3, TP63
45wound healingGO:00420609.5BMP4, TGFA, TGFB3, TGFBR2
46skeletal system developmentGO:00015019.3BMP4, COL2A1, FGFR1, FOXC2, TCOF1, TP63
47palate developmentGO:00600219.3COL2A1, FOXE1, GABRB3, MSX1, SATB2, TGFB3
48regulation of gene expressionGO:00104689.2BMP4, COL2A1, FGFR1, SATB2, TGFBR2
49positive regulation of transcription from RNA polymerase II promoterGO:00459448.7BMP4, FGFR2, FOXC2, MSX1, SATB2, TGFB3
50negative regulation of transcription from RNA polymerase II promoterGO:00001227.9BMP4, FGFR1, FGFR2, FOXC2, FOXE1, MSX1

Molecular functions related to Cleft Palate, Isolated according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1fibroblast growth factor-activated receptor activityGO:000500710.5FGFR1, FGFR2
2type I transforming growth factor beta receptor bindingGO:003471310.5TGFB3, TGFBR2
3transforming growth factor beta bindingGO:005043110.4TGFB3, TGFBR2
4sequence-specific DNA bindingGO:00435659.4FOXC2, FOXE1, MSX1, SATB2, TP63

Sources for Cleft Palate, Isolated

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
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31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
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40MGI
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44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
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57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet