Cleft Palate, Isolated malady
Genetic diseases, Oral diseases, Fetal diseases, Rare diseases categories
OMIM:45 Cleft palate as an isolated malformation behaves as an entity distinct from cleft lip with or without cleft palate (see... (119540) more...
MalaCards based summary: Cleft Palate, Isolated, also known as cleft palate, is related to cleft lip +/- cleft palate and mental retardation, and has symptoms including non-midline cleft lip, autosomal dominant inheritance and cleft palate. An important gene associated with Cleft Palate, Isolated is UBB (ubiquitin B). Related mouse phenotype endocrine/exocrine gland.
Cleft Palate, Isolated, Aliases & Descriptions:
Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Fetal diseases, Rare diseases
Anatomical: Oral diseases
ICD10: 26 25
Developmental anomalies during embryogenesis
Characteristics (Orphanet epidemiological data):47
Inheritance: Multigenic/multifactorial,Not applicable; Prevalence: 1-5/10000 (Europe),1-5/10000 (Austria),1-5/10000 (Belgium),1-5/10000 (Croatia),>1/1000 (Denmark),1-5/10000 (France),1-5/10000 (Germany),6-9/10000 (Hungary),1-5/10000 (Ireland),1-5/10000 (Italy),6-9/10000 (Malta),1-5/10000 (Netherlands),6-9/10000 (Norway),1-5/10000 (Poland),1-5/10000 (Portugal),1-5/10000 (Spain),1-5/10000 (Switzerland),6-9/10000 (United Kingdom),1-5/10000 (Ukraine); Age of onset: Antenatal,Neonatal; Age of death: normal life expectancy
Symptoms by clinical synopsis from OMIM:119540
Clinical features from OMIM:119540
HPO human phenotypes related to Cleft Palate, Isolated:(show all 9)
Search GEO for disease gene expression data for Cleft Palate, Isolated.
Biological processes related to Cleft Palate, Isolated according to GeneCards Suite gene sharing:
26ICD10 via Orphanet
34MESH via Orphanet
46OMIM via Orphanet
56SNOMED-CT via Orphanet
61UMLS via Orphanet