MCID: CLN041
MIFTS: 9

Cln14 Disease

Categories: Genetic diseases, Neuronal diseases

Aliases & Classifications for Cln14 Disease

MalaCards integrated aliases for Cln14 Disease:

Name: Cln14 Disease 24 29
Kctd7-Related Neuronal Ceroid-Lipofuscinosis 24

Classifications:



Summaries for Cln14 Disease

MalaCards based summary : Cln14 Disease, is also known as kctd7-related neuronal ceroid-lipofuscinosis. An important gene associated with Cln14 Disease is KCTD7 (Potassium Channel Tetramerization Domain Containing 7). The drugs Belinostat and Doxorubicin have been mentioned in the context of this disorder.

Related Diseases for Cln14 Disease

Symptoms & Phenotypes for Cln14 Disease

Drugs & Therapeutics for Cln14 Disease

Drugs for Cln14 Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Belinostat Approved, Investigational Phase 1, Phase 2 866323-14-0
2
Doxorubicin Approved, Investigational Phase 1, Phase 2 23214-92-8 31703
3
Doxil Approved June 1999 Phase 1, Phase 2 31703
4 Anti-Bacterial Agents Phase 1, Phase 2
5 Antibiotics, Antitubercular Phase 1, Phase 2
6 Histone Deacetylase Inhibitors Phase 1, Phase 2
7 Topoisomerase Inhibitors Phase 1, Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 A Phase I/II Clinical Trial of PXD101 in Combination With Doxorubicin in Patients With Soft Tissue Sarcomas Completed NCT00878800 Phase 1, Phase 2 PXD101;Doxorubicin

Search NIH Clinical Center for Cln14 Disease

Genetic Tests for Cln14 Disease

Genetic tests related to Cln14 Disease:

id Genetic test Affiliating Genes
1 Cln14 Disease 29 24 KCTD7

Anatomical Context for Cln14 Disease

Publications for Cln14 Disease

Variations for Cln14 Disease

Expression for Cln14 Disease

Search GEO for disease gene expression data for Cln14 Disease.

Pathways for Cln14 Disease

GO Terms for Cln14 Disease

Sources for Cln14 Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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