MCID: CCC001
MIFTS: 55

Coccidioidomycosis malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Coccidioidomycosis

Aliases & Descriptions for Coccidioidomycosis:

Name: Coccidioidomycosis 12 50 56 52 3 42 14 69
Valley Fever 50 56 41 3
Primary Extrapulmonary Coccidioidomycosis 12 69
Coccidiosis 50 69
Primary Pulmonary Coccidioidomycosis 69
Coccidioides Immitis Infection 50
San Joaquin Valley Fever 56
Acute Coccidioidomycosis 69
Coccidioides Infection 56
Enteric Coccidiosis 69
California Disease 56
San Joaquin Fever 50
Desert Rheumatism 56
Desert Fever 56

Characteristics:

Orphanet epidemiological data:

56
coccidioidomycosis
Inheritance: Not applicable; Age of onset: All ages;

Classifications:

Orphanet: 56  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:13450
ICD10 33 B38 B38.9
ICD9CM 35 114 114.9
MeSH 42 D003047
NCIt 47 C84642
Orphanet 56 ORPHA228123
MESH via Orphanet 43 D003047
UMLS via Orphanet 70 C0009186
UMLS 69 C0009186

Summaries for Coccidioidomycosis

MedlinePlus : 41 valley fever is a disease caused by a fungus (or mold) called coccidioides. the fungi live in the soil of dry areas like the southwestern u.s. you get it from inhaling the spores of the fungus. the infection cannot spread from person to person. anyone can get valley fever. but it's most common among older adults, especially those 60 and older. people who have recently moved to an area where it occurs are at highest risk for infection. other people at higher risk include workers in jobs that expose them to soil dust. these include construction workers, agricultural workers, and military forces doing field training. african americans and asians women in their third trimester of pregnancy people with weak immune systems valley fever is often mild, with no symptoms. if you have symptoms, they may include a flu-like illness, with fever, cough, headache, rash, and muscle aches. most people get better within several weeks or months. a small number of people may develop a chronic lung or widespread infection. valley fever is diagnosed by testing your blood, other body fluids, or tissues. many people with the acute infection get better without treatment. in some cases, doctors may prescribe antifungal drugs for acute infections. severe infections require antifungal drugs. centers for disease control and prevention

MalaCards based summary : Coccidioidomycosis, also known as valley fever, is related to tuberculosis and cryptococcosis, and has symptoms including conjunctivitis, arthritis and chest pain. An important gene associated with Coccidioidomycosis is IFNGR1 (Interferon Gamma Receptor 1), and among its related pathways/superpathways are Innate Immune System and Toll-like Receptor Signaling Pathway. The drugs Bevacizumab and Fluconazole have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and skin, and related phenotypes are hematopoietic system and digestive/alimentary

Disease Ontology : 12 A primary systemic mycosis that results_in systemic fungal infection, has material basis in Coccidioides immitis, transmitted_by airborne spores and has symptom conjunctivitis, has symptom arthritis, has symptom chest pain and results_in_formation_of skin nodules.

CDC : 3 Valley fever, also called coccidioidomycosis, is an infection caused by the fungus Coccidioides. The fungus is known to live in the soil in the southwestern United States and parts of Mexico and Central and South America. The fungus was also recently found in south-central Washington. People can get Valley fever by breathing in the microscopic fungal spores from the air, although most people who breathe in the spores don’t get sick. Usually, people who get sick with Valley fever will get better on their own within weeks to months, but some people will need antifungal medication. Certain groups of people are at higher risk for becoming severely ill. It’s difficult to prevent exposure to Coccidioides in areas where it’s common in the environment, but people who are at higher risk for severe Valley fever should try to avoid breathing in large amounts of dust if they’re in these areas.

Wikipedia : 71 Coccidioidomycosis (/kɒkˌsɪdiɔɪdoʊmaɪˈkoʊsɪs/, kok-sid-ee-oy-doh-my-KOH-sis), commonly known... more...

Related Diseases for Coccidioidomycosis

Diseases related to Coccidioidomycosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 172)
id Related Disease Score Top Affiliating Genes
1 tuberculosis 29.6 CD4 CD40LG
2 cryptococcosis 29.3 CD4 CD40LG
3 rift valley fever 12.6
4 coccidiosis 12.4
5 cryptosporidiosis 11.1
6 sarcocystosis 11.1
7 toxoplasmosis 10.8
8 cystoisosporiasis 10.8
9 cyclosporiasis 10.8
10 ethmoid sinus cancer 10.2 STAT1 TLR4
11 pseudoainhum 10.2 MBL2 TLR4
12 transient tic disorder 10.2 CD4 IFNGR1
13 nephropathy familial with hyperuricemia 10.2 MBL2 TLR4
14 hypoparathyroidism-retardation-dysmorphism syndrome 10.2 CD4 TLR4
15 parasitic ichthyosporea infectious disease 10.2 CD4 TLR4
16 rheumatoid factor-negative juvenile idiopathic arthritis without anti-nuclear antibodies 10.2 CD4 TLR4
17 spotted fever 10.2 CD40LG TLR4
18 hypertensive heart disease 10.2 CD40LG TLR4
19 phlyctenulosis 10.1 CD4 MBL2
20 gastric leiomyoma 10.1 CD40LG TLR4
21 megaloblastic anemia 10.1 CD40LG TLR4
22 indomethacin antenatal infection 10.1 CD40LG MBL2
23 omsk hemorrhagic fever 10.1 CD40LG TLR4
24 lateral cystocele 10.1 CD40LG TLR4
25 glycogen storage disease viii 10.1 CD40LG TLR4
26 breast adenomyoepithelioma 10.1 CD4 STAT1
27 isolated growth hormone deficiency 10.1 IFNGR1 STAT1 TLR4
28 dieulafoy lesion 10.1 CD4 MBL2
29 good syndrome 10.1 CD40LG MBL2
30 prostate carcinoma in situ 10.1 CD4 CD40LG
31 colloid adenoma 10.1 CD4 CD40LG
32 retinal microaneurysm 10.1 CD4 CD40LG
33 chronic duodenal ileus 10.1 CD4 CD40LG
34 cysticercosis 10.1 CD4 CD40LG
35 rickettsialpox 10.1 CD40LG TLR4
36 atypical breast papilloma 10.1 CD4 CD40LG
37 angiolipoma 10.1 CD4 CD40LG
38 infundibulocystic basal cell carcinoma 10.1 CD4 CD40LG
39 generalized atherosclerosis 10.1 CD4 CD40LG
40 bursitis 10.1 CD4 CD40LG
41 syphilis 10.1 CD4 CD40LG
42 dermatitis herpetiformis 10.1 CD4 CD40LG
43 immunoglobulin beta deficiency 10.1 CD4 CD40LG
44 hydronephrosis 10.1 CD4 CD40LG
45 cerebellar liponeurocytoma 10.1 CD40LG STAT1
46 facial paralysis 10.1 CD4 CD40LG
47 polyneuropathy due to drug 10.1 CD4 CD40LG
48 neuropathy, hereditary thermosensitive 10.1 CD4 CD40LG
49 human immunodeficiency virus infectious disease 10.1 CD4 CD40LG
50 thrombophlebitis migrans 10.1 CD4 CD40LG

Graphical network of the top 20 diseases related to Coccidioidomycosis:



Diseases related to Coccidioidomycosis

Symptoms & Phenotypes for Coccidioidomycosis

Symptoms:

12
  • conjunctivitis
  • arthritis
  • chest pain

UMLS symptoms related to Coccidioidomycosis:


fever, pruritus

MGI Mouse Phenotypes related to Coccidioidomycosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.86 STAT1 TLR4 CD4 CD40LG CD69 CLEC7A
2 digestive/alimentary MP:0005381 9.72 CD4 CLEC7A IFNGR1 STAT1 TLR4
3 homeostasis/metabolism MP:0005376 9.7 CD4 CD40LG CLEC7A IFNGR1 MBL2 STAT1
4 immune system MP:0005387 9.56 CD4 CD40LG CD69 CLEC7A IFNGR1 MBL2
5 integument MP:0010771 9.02 CD4 CD40LG IFNGR1 STAT1 TLR4

Drugs & Therapeutics for Coccidioidomycosis

Drugs for Coccidioidomycosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 96)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bevacizumab Approved, Investigational Phase 4 216974-75-3
2
Fluconazole Approved Phase 4,Phase 3 86386-73-4 3365
3
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 22916-47-8 4189
4
Levoleucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1 68538-85-2
5
Pyrimethamine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 58-14-0 4993
6
Spiramycin Approved Phase 4,Phase 3,Phase 1 24916-50-5
7
Sulfadiazine Approved, Vet_approved Phase 4,Phase 3,Phase 2 68-35-9 5215
8
Valproic Acid Approved, Investigational Phase 4 99-66-1 3121
9
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 59-30-3 6037
10
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 58-05-9 54575, 6560146 143
11 Anti-Infective Agents Phase 4,Phase 3,Phase 1,Phase 2
12 Antiparasitic Agents Phase 4,Phase 3,Phase 1,Phase 2
13 Angiogenesis Inhibitors Phase 4,Phase 1,Phase 2
14 Angiogenesis Modulating Agents Phase 4,Phase 1,Phase 2
15 Antifungal Agents Phase 4,Phase 3,Phase 1,Phase 2
16 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Phase 3,Phase 1
17 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
18 Hormone Antagonists Phase 4,Phase 3
19 Hormones Phase 4,Phase 3
20 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3
21 Steroid Synthesis Inhibitors Phase 4,Phase 3
22 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
23 Antidotes Phase 4,Phase 2,Phase 1
24 Antimalarials Phase 4,Phase 3,Phase 2,Phase 1
25 Antiprotozoal Agents Phase 4,Phase 3,Phase 1,Phase 2
26 Calcium, Dietary Phase 4,Phase 2,Phase 1
27 Folic Acid Antagonists Phase 4,Phase 3,Phase 2,Phase 1
28 Protective Agents Phase 4,Phase 2,Phase 1
29 Vitamin B Complex Phase 4,Phase 3,Phase 2,Phase 1
30 Bone Density Conservation Agents Phase 4
31 Micronutrients Phase 4
32 Trace Elements Phase 4
33 Vitamins Phase 4
34 Anticonvulsants Phase 4
35 Antimanic Agents Phase 4
36 Central Nervous System Depressants Phase 4
37 GABA Agents Phase 4
38 Neurotransmitter Agents Phase 4,Phase 2
39 Psychotropic Drugs Phase 4,Phase 2
40 Tranquilizing Agents Phase 4
41 Folate Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1
42 Vitamin B9 Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1
43
Nitazoxanide Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 55981-09-4 41684
44
Posaconazole Approved, Investigational, Vet_approved Phase 3 171228-49-2 147912
45
Clotrimazole Approved, Vet_approved Phase 3 23593-75-1 2812
46
Sulfamethoxazole Approved Phase 3 723-46-6 5329
47
Trimethoprim Approved, Vet_approved Phase 3 738-70-5 5578
48 Renal Agents Phase 3
49 Trimethoprim, Sulfamethoxazole Drug Combination Phase 3
50
Atovaquone Approved Phase 2,Phase 1 95233-18-4 74989

Interventional clinical trials:

(show top 50) (show all 56)
id Name Status NCT ID Phase
1 Intravitreal Bevacizumab in Recalcitrant Inflammatory Ocular Neovascularization Completed NCT00645697 Phase 4
2 Early Fluconazole Treatment for Coccidiodomycosis Pneumonia Recruiting NCT02663674 Phase 4
3 Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis Recruiting NCT00004317 Phase 4
4 Pilot Trial of Valproate as Adjunctive Treatment for Toxoplasma Gondii Infection in Early Course Schizophrenia Active, not recruiting NCT02011750 Phase 4
5 Assessment of Two Therapeutic Strategies in the Treatment of Children With Congenital Toxoplasmosis Unknown status NCT01202500 Phase 3
6 POS vs FLU for First Line Treatment of Coccidioidomycosis (Study P04558Am1)(COMPLETED) Completed NCT00423267 Phase 3
7 A Multi-center Study of Spherule-Derived Coccidioidin Completed NCT00690092 Phase 3
8 Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081) Completed NCT00000676 Phase 3
9 Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During Pregnancy Completed NCT01189448 Phase 3
10 Influence of Trimethoprim-Sulfamethoxazole for the Recurrence of Ocular Toxoplasmosis Completed NCT01449877 Phase 3
11 Safety and Effectiveness of Nitazoxanide for the Treatment of Cryptosporidiosis in AIDS Patients Terminated NCT00004986 Phase 3
12 Safety/Immunogenicity/Genetic Drift of MP-12 Rift Valley Fever Vaccine Completed NCT00415051 Phase 2
13 Safety and Immunogenicity Study of Rift Valley Fever Vaccine Completed NCT00584194 Phase 2
14 Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine in Tanzanian Infants Completed NCT00289185 Phase 2
15 Double-blind Study of Safety and Immunogenicity of Two Candidate Malaria Vaccines in Gabonese Children Completed NCT00307021 Phase 2
16 Nitazoxanide for the Treatment of Chronic Diarrhea in HIV Infected Children Completed NCT00055107 Phase 1, Phase 2
17 A Study of Nitazoxanide in Patients With AIDS and Diarrhea Caused by Cryptosporidium Completed NCT00001081 Phase 2
18 Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic Encephalitis Completed NCT00000794 Phase 2
19 A Double-Blind, Placebo-Controlled Trial of Paromomycin for Treatment of Cryptosporidiosis in Patients With Advanced HIV Disease and CD4 Counts Under 150 Cells/mm3 Completed NCT00000771 Phase 2
20 Primary Prophylaxis of Cerebral Toxoplasmosis in HIV-Infected Patients Completed NCT00000643 Phase 2
21 Safety and Immunogenicity Study of Rift Valley Fever Vaccine, Inactivated Enrolling by invitation NCT00869713 Phase 2
22 Sertraline in Addition to Standard of Care Treatment for Coccidioidomycosis Not yet recruiting NCT02908334 Phase 2
23 Safety and PK of Nikkomycin Z for Coccidioides Pneumonia Treatment Terminated NCT00614666 Phase 1, Phase 2
24 Interleukin 12 (IL-12) for the Treatment of Cryptosporidiosis in AIDS Patients Terminated NCT00057486 Phase 1, Phase 2
25 Antiretroviral Drug Interaction Study in Volunteers With HIV Completed NCT01479361 Phase 1
26 A Randomized, Multicenter, Double-Blind, Parallel-Group, Placebo-Controlled Trial of the Efficacy and Safety of Bovine Anti-Cryptosporidium Immunoglobulin (BACI) in the Treatment of Cryptosporidium Enteritis in AIDS Patients Completed NCT00002248 Phase 1
27 A Study of Letrazuril in the Treatment of AIDS-Related Diarrhea Completed NCT00001018 Phase 1
28 A Study of Spiramycin in the Treatment of Patients With AIDS-Related Diarrhea Completed NCT00000980 Phase 1
29 A Study of Pyrimethamine in the Treatment of Infection by a Certain Parasite in HIV-Positive Patients Completed NCT00000973 Phase 1
30 A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDS Completed NCT00000966 Phase 1
31 Breast Milk Composition and HIV-exposed/Unexposed Early Infant Growth and Infectious Disease Events Unknown status NCT01699841
32 A Study to Evaluate the Use of Nitazoxanide to Treat Cryptosporidiosis Unknown status NCT00002158
33 Risk of Coccidioidomycosis in Patients Receiving Anti-TNF and Other Biologic Agents for an Inflammatory Arthritis Completed NCT00796809
34 Rift Valley Fever in Kenya Completed NCT00287014
35 A Study of Fluconazole in the Prevention of Fungal Infections in HIV-Infected Patients Living in Areas Where Fungal Infections Are Common Completed NCT00002325
36 Open, Non-Comparative Study of Fluconazole in Patients With Coccidioidal Meningitis Completed NCT00002010
37 Cerebral Toxoplasmosis and AIDS Completed NCT00803621
38 Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis Completed NCT02843438
39 Transmission and the Respiratory Tract in Cryptosporidiosis Completed NCT00507871
40 Trial of Ceramic Water Filters to Reduce Cryptosporidium Infection in Kenya Completed NCT01695304
41 Azithromycin in the Treatment of Cryptosporidiosis in Patients Who Have Not Had Success With Other Drugs Completed NCT00002328
42 A 28-Day Study of Diclazuril in the Treatment of Cryptosporidiosis in Patients With AIDS Completed NCT00002278
43 The Effectiveness of Cow's Milk Immune Globulin in the Treatment of AIDS-Related Diarrhea Completed NCT00002264
44 Azithromycin in the Treatment of Cryptosporidiosis in Patients With Acquired Immune Deficiency Syndrome (AIDS): A Randomized, Multi-Center, Placebo-Controlled, Double-Blind Study Completed NCT00002082
45 Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse Completed NCT00002064
46 Open-Label "Compassionate" Use Study of Spiramycin for the Treatment of Diarrhea Due to Chronic Cryptosporidiosis in Immunocompromised Patients Completed NCT00002062
47 Protocol For the Treatment of Cryptosporidiosis in AIDS Patients With Diclazuril (R64,433) Completed NCT00002027
48 A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-Sulfadiazine Completed NCT00001994
49 A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDS Completed NCT00000674
50 A Randomized Prospective Study of Pyrimethamine Therapy for Prevention of Toxoplasmic Encephalitis in HIV-Infected Individuals With Serologic Evidence of Latent Toxoplasma Gondii Infection Completed NCT00000666

Search NIH Clinical Center for Coccidioidomycosis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: coccidioidomycosis

Genetic Tests for Coccidioidomycosis

Anatomical Context for Coccidioidomycosis

MalaCards organs/tissues related to Coccidioidomycosis:

39
Lung, Testes, Skin, Liver, Prostate, Brain, Bone

Publications for Coccidioidomycosis

Articles related to Coccidioidomycosis:

(show top 50) (show all 594)
id Title Authors Year
1
Fluoroquinolone therapy could influence the clinical signs of pulmonary coccidioidomycosis. ( 28081876 )
2017
2
What to Do for the Asymptomatic Pulmonary Coccidioidal Nodule or Cavity in Immunosuppressed Patients? A Focus in the Recent Coccidioidomycosis Guidelines. ( 27986674 )
2017
3
Disseminated coccidioidomycosis presenting with intramedullary spinal cord abscesses: Management challenges. ( 28053850 )
2017
4
Large-Scale Land Development, Fugitive Dust, and Increased Coccidioidomycosis Incidence in the Antelope Valley of California, 1999-2014. ( 28084574 )
2017
5
ENHANCED ANTIBODY DETECTION AND DIAGNOSIS OF COCCIDIOIDOMYCOSIS WITH THE MIRAVISTA IGG AND IGM DETECTION ENZYME IMMUNOASSAY. ( 28053216 )
2017
6
Coccidioidomycosis: Surgical Issues and Implications. ( 27740893 )
2016
7
Integrative Medicine Preferences Among Coccidioidomycosis (Valley Fever) Patients. ( 27557127 )
2016
8
Coccidioidomycosis with Pericardial Involvement: Case Report and Literature Review. ( 26642905 )
2016
9
Rare Dysuria: Prostatic Abscess due to Disseminated Coccidioidomycosis. ( 27617214 )
2016
10
Coccidioidomycosis: Experience From a Children's Hospital in an Area of Endemicity. ( 26908496 )
2016
11
Cold subcutaneous abscesses as the first manifestation of disseminated coccidioidomycosis in an immunocompromised host. ( 26607200 )
2016
12
Awareness and Environmental Exposures Related to Coccidioidomycosis Among Inmates at Two California Prisons, 2013. ( 26984139 )
2016
13
Management of temporomandibular joint Coccidioidomycosis. ( 27077269 )
2016
14
Coccidioidomycosis. ( 26739609 )
2016
15
Coccidioidomycosis Transmission Through Organ Transplantation: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee. ( 27376472 )
2016
16
Presentations of coccidioidomycosis in the ED. ( 26952967 )
2016
17
Complications and Yield of Computed Tomography-Guided Transthoracic Core Needle Biopsy of Lung Nodules at a High-Volume Academic Center in an Endemic Coccidioidomycosis Area. ( 26980483 )
2016
18
Coccidioidomycosis with diffuse miliary pneumonia. ( 26722164 )
2016
19
Coccidioidomycosis in Patients with Selected Solid Organ Cancers: A Case Series and Review of Medical Literature. ( 27492230 )
2016
20
Reactivation of coccidioidomycosis: a prosthetic joint infection in Spain. ( 26638217 )
2016
21
Cytologic diagnosis of coccidioidomycosis: Spectrum of findings in Southern Arizona patients over a 10 year period. ( 26800146 )
2016
22
Risk Factors and Epidemiology of Coccidioidomycosis Demonstrated by a Case of Spontaneous Pulmonary Rupture of Cavitary Coccidioidomycosis. ( 26904326 )
2016
23
Coccidioidomycosis in infants: A retrospective case series. ( 26829719 )
2016
24
Effect of Geography on the Analysis of Coccidioidomycosis-Associated Deaths, United States. ( 27649029 )
2016
25
PET/CT: First-Line Exam To Assess Disease Extent of Disseminated Coccidioidomycosis. ( 27102664 )
2016
26
2016 Infectious Diseases Society of America (IDSA) Clinical Practice Guideline for the Treatment of Coccidioidomycosis. ( 27470238 )
2016
27
Executive Summary: 2016 Infectious Diseases Society of America (IDSA) Clinical Practice Guideline for the Treatment of Coccidioidomycosis. ( 27559032 )
2016
28
Hospitalized burden and outcomes of coccidioidomycosis: A nationwide analysis, 2005-2012. ( 27703017 )
2016
29
Case of coccidioidomycosis in Ireland. ( 27516109 )
2016
30
Primary Cutaneous Coccidioidomycosis Presenting as a Recurrent Preauricular Cyst. ( 27319963 )
2016
31
Clinicopathologic and Histopathologic Renal Abnormalities in Dogs with Coccidioidomycosis. ( 27717191 )
2016
32
Treatment considerations in pulmonary coccidioidomycosis. ( 27635942 )
2016
33
Risk Factors and Spatial Distribution of Canine Coccidioidomycosis in California, 2005-2013. ( 26801836 )
2016
34
Coccidioidomycosis-Associated Deaths in California, 2000-2013. ( 27453596 )
2016
35
Coccidioidomycosis and Blastomycosis: Endemic Mycotic Co-Infections in the HIV Patient. ( 25584108 )
2015
36
Mini-Review of Published Reports on Coccidioidomycosis in China. ( 26354712 )
2015
37
Disseminated cutaneous coccidioidomycosis in a liver transplant patient. ( 27051736 )
2015
38
Whole glucan particles as a vaccine against systemic coccidioidomycosis. ( 26297127 )
2015
39
Coccidioidomycosis and the skin: a comprehensive review. ( 26560205 )
2015
40
Empyema necessitatis: unique presentation in a coccidioidomycosis case. ( 25876208 )
2015
41
Coccidioidomycosis in Biopsies with Presumptive Diagnosis of Malignancy in Dogs: Report of Three Cases and Comparative Discussion of Published Reports. ( 26419685 )
2015
42
Chronic Interstitial Granulomatous Dermatitis in Coccidioidomycosis. ( 26574343 )
2015
43
Diagnosis, treatment, and outcomes of coccidioidomycosis in allogeneic stem cell transplantation. ( 25682795 )
2015
44
Universal fungal prophylaxis and risk of coccidioidomycosis in liver transplant recipients living in an endemic area. ( 25482428 )
2015
45
444: DISSEMINATED COCCIDIOIDOMYCOSIS IN CHILDREN. ( 26570105 )
2015
46
Gastrointestinal Coccidioidomycosis. ( 25887112 )
2015
47
THE TREATMENT OF COCCIDIOIDOMYCOSIS. ( 26465370 )
2015
48
Coccidioidomycosis Presented as a Pelvic Mass in an Otherwise Healthy Female. ( 26586713 )
2015
49
Coccidioidomycosis Masquerading as Eosinophilic Ascites. ( 26266062 )
2015
50
Evaluation of the Specificity of Two Enzyme Immunoassays for Coccidioidomycosis by Using Sera from a Region of Endemicity and a Region of Nonendemicity. ( 26245352 )
2015

Variations for Coccidioidomycosis

Expression for Coccidioidomycosis

Search GEO for disease gene expression data for Coccidioidomycosis.

Pathways for Coccidioidomycosis

Pathways related to Coccidioidomycosis according to GeneCards Suite gene sharing:

(show all 18)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.65 CD4 CD40LG CLEC7A IFNGR1 MBL2 STAT1
2
Show member pathways
12.6 IFNGR1 MBL2 STAT1 TLR4
3
Show member pathways
12.27 CD4 CD40LG IFNGR1 STAT1
4
Show member pathways
12.16 CD4 IFNGR1 STAT1 TLR4
5
Show member pathways
11.97 IFNGR1 STAT1 TLR4
6
Show member pathways
11.87 IFNGR1 STAT1 TLR4
7 11.85 IFNGR1 STAT1 TLR4
8 11.79 CLEC7A MBL2 TLR4
9
Show member pathways
11.73 CD40LG IFNGR1 STAT1 TLR4
10
Show member pathways
11.59 CD4 STAT1 TLR4
11
Show member pathways
11.58 IFNGR1 STAT1
12 11.51 CLEC7A IFNGR1 STAT1 TLR4
13 11.27 CD40LG TLR4
14 11.16 CD4 CD40LG CD69
15 11.13 CD4 CD40LG
16 11.12 IFNGR1 STAT1
17 11.08 CD40LG TLR4
18
Show member pathways
10.95 CD4 IFNGR1 STAT1 TLR4

GO Terms for Coccidioidomycosis

Cellular components related to Coccidioidomycosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.55 CD4 CD40LG CD69 IFNGR1 TLR4
2 cell surface GO:0009986 9.26 CD4 CD40LG MBL2 TLR4
3 external side of plasma membrane GO:0009897 8.92 CD4 CD40LG CD69 TLR4

Biological processes related to Coccidioidomycosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 defense response to Gram-negative bacterium GO:0050829 9.37 CD4 TLR4
2 T cell activation GO:0042110 9.32 CD4 CLEC7A
3 positive regulation of interleukin-12 production GO:0032735 9.26 CD40LG TLR4
4 immune system process GO:0002376 9.26 CD4 CLEC7A MBL2 TLR4
5 positive regulation of interleukin-10 production GO:0032733 9.16 CD40LG TLR4
6 regulation of interferon-gamma-mediated signaling pathway GO:0060334 8.62 IFNGR1 STAT1

Molecular functions related to Coccidioidomycosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 9.33 CD4 CD69 TLR4
2 tumor necrosis factor receptor binding GO:0005164 8.96 CD40LG STAT1
3 carbohydrate binding GO:0030246 8.8 CD69 CLEC7A MBL2

Sources for Coccidioidomycosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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