MCID: CLL021
MIFTS: 38

Collagenous Colitis malady

Categories: Rare diseases, Gastrointestinal diseases

Aliases & Classifications for Collagenous Colitis

About this section

Aliases & Descriptions for Collagenous Colitis:

Name: Collagenous Colitis 11 47 49 13
Colitis, Collagenous 38 67
 
Microscopic Colitis, Collagenous Type 47

Classifications:



External Ids:

Disease Ontology11 DOID:0060183
ICD1029 K52.89
SNOMED-CT61 19311003
MeSH38 D046729
NCIt44 C27021

Summaries for Collagenous Colitis

About this section
Wikipedia:70 Collagenous colitis is an inflammatory bowel disease affecting the colon specifically with peak... more...

MalaCards based summary: Collagenous Colitis, also known as colitis, collagenous, is related to eosinophilic gastritis and polyarteritis nodosa. An important gene associated with Collagenous Colitis is RNASE3 (Ribonuclease A Family Member 3). Affiliated tissues include colon, small intestine and t cells.

Disease Ontology:11 A colitis characterized by a distinctive thickening of the subepithelial collagen table.

Related Diseases for Collagenous Colitis

About this section

Diseases related to Collagenous Colitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 117)
idRelated DiseaseScoreTop Affiliating Genes
1eosinophilic gastritis29.4CHGA, NOS2
2polyarteritis nodosa29.4CD79A, MPO
3clostridium difficile colitis25.7CD79A, CHGA, CHGB, COL14A1, EPX, MPO
4lymphocytic colitis11.3
5microscopic colitis11.3
6colitis10.8
7paratyphoid fever10.4MPO, RNASE3
8winchester syndrome10.4EPX, RNASE3
9cecum adenoma10.4EPX, RNASE3
10fungal gastritis10.4EPX, RNASE3
11eosinophilic cystitis10.3EPX, MPO
12motor peripheral neuropathy10.3EPX, MPO
13olfactory neural tumor10.3EPX, MPO
14melanoacanthoma10.3EPX, RNASE3
15osteoblastoma10.3CHGA, EPX
16loeffler syndrome10.2EPX, RNASE3
17atypical follicular adenoma10.2MPO, NOS2
18blind hypotensive eye10.2EPX, RNASE3
19glucosidase acid-1,4-alpha deficiency10.1CHGA, CHGB
20chronic cystitis10.1CD79A, RNASE3
21crustacean allergy10.1CD79A, RNASE3
22osteoclast-like giant cell neoplasm of the pancreas10.1CHGA, CHGB
23ulcerative colitis10.1
24apple allergy10.1CD79A, RNASE3
25arthritis10.1
26transmitted_by10.1EPX, RNASE3
27benign meningioma10.1CD79A, MPO
28arteriosclerosis10.1CD79A, MPO
29acute porphyria10.1EPX, MPO, RNASE3
30peanut allergy10.1CD79A, RNASE3
31proliferative glomerulonephritis10.1CD79A, MPO
32gait apraxia10.1CD79A, RNASE3
33acquired thrombocytopenia10.1CD79A, MPO
34autoimmune neuropathy10.0CD79A, RNASE3
35eosinophilic fasciitis10.0CD79A, MPO
36diarrhea10.0
37suppurative uveitis10.0CD79A, MPO
38chromoblastomycosis10.0CD79A, MPO
39complex partial epilepsy10.0CD79A, MPO
40meibomian cyst10.0CD79A, MPO
41lung squamous cell carcinoma10.0CD79A, MPO
42vaginitis10.0CD79A, RNASE3
43yellow fever10.0CD79A, MPO
44pulmonary alveolar proteinosis10.0CD79A, MPO
45geotrichosis10.0CD79A, RNASE3
46borst-jadassohn intraepidermal carcinoma10.0CD79A, RNASE3
47epidermolysis bullosa simplex superficialis10.0CD79A, RNASE3
48sporotrichosis10.0CD79A, RNASE3
49chemical colitis10.0CD79A, CHGA
50sarcoid meningitis10.0CD79A, RNASE3

Graphical network of the top 20 diseases related to Collagenous Colitis:



Diseases related to collagenous colitis

Symptoms for Collagenous Colitis

About this section

Drugs & Therapeutics for Collagenous Colitis

About this section

Drugs for Collagenous Colitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
BudesonideapprovedPhase 342251333-22-363006, 5281004
Synonyms:
(11-beta,16-alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione
(11beta,16alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione
(4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
(R,S)-11b,16a,17,21,tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with buty raldehyde
(RS)-(11beta,16alpha)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione
(RS)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with butyraldehyde
(S)-16alpha,17-(Butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione
11beta,21-dihydroxy-16alpha,17alpha-(butane-1,1-diyldioxy)pregna-1,4-diene-3,20-dione
16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione
16,17-Butylidenebis(oxy)-11-,21-dihydroxypregna-1,4-diene-3,20-dione
16-alpha,17-alpha-Butylidenedioxy-11-beta,21-dihydroxy-1,4-pregnadiene-3,20-dione
16alpha(R),17-(Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione
16alpha-,17alpha--butylidenedioxypregna-1,4-diene-11beta-,21-diol-3,20-dione
51333-22-3
AC-4697
AC1L1DQE
AC1L1Y6Y
AC1L22VC
AC1MHWI7
B 7777
B7777_SIGMA
BPBio1_000523
BRD-A34299591-001-03-4
BRD-A82238138-001-01-7
BSPBio_000475
BSPBio_002160
Bidien
Bio-0010
Budecort Inhaler
Budenofalk
Budeson
Budesonide (JAN/USAN/INN)
Budesonide Easyhaler
Budesonide MMX
Budesonide [USAN:INN:BAN:JAN]
Budesonido
Budesonido [INN-Spanish]
Budesonidum
Budesonidum [INN-Latin]
Budiair
Budicort
C25H34O6
CCRIS 5230
CHEBI:3207
CHEBI:656601
CHEMBL1370
CID2462
CID3033890
CID40000
CID5281004
CID63006
CPD000058337
Cortivent
D00246
DB01222
Desowen
Dexbudesonide
Dexbudesonide [INN]
DivK1c_000475
EINECS 257-139-7
EINECS 257-160-1
EINECS 257-161-7
EU-0100174
Entocort
Entocort EC
Entocort EC (TN)
Giona Easyhaler
HMS1569H17
HMS1921I22
HMS2094I13
HMS501H17
Horacort
 
IDI1_000475
Inflammide
KBio1_000475
KBio3_001660
KBioGR_001361
LS-187734
LS-7235
Lopac0_000174
MAP-0010
MLS000028507
MLS001077323
MLS002207112
Micronyl
Miflonide
MolPort-002-529-265
MolPort-003-666-332
MolPort-003-986-909
NCGC00015165-03
NCGC00021318-03
NCGC00021318-06
NCGC00089747-02
NCGC00089747-03
NCGC00089747-04
NCGC00178789-01
NINDS_000475
Noex
Preferid
Pregna-1,4-diene-3,20-dione, 16,17-butylidenebis(oxy)-11,21-dihydroxy-, (11beta,16alpha(R))-, and 16alpha,17-((S)-Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione
Prestwick0_000518
Prestwick1_000518
Prestwick2_000518
Prestwick3_000518
Prestwick_840
Pulmaxan
Pulmaxan turbohaler
Pulmicort
Pulmicort (TN)
Pulmicort Flexhaler
Pulmicort Nebuamp
Pulmicort Respules
Pulmicort Topinasal
Pulmicort Turbuhaler
Pulmicort turbuhaler
Respules
Rhinocort
Rhinocort Aqua
Rhinocort Turbuhaler
Rhinocort alpha
Rhinocort, Pulmicort , Entocort, Symbicort, Noex. Entocort EC, Budesonide
Rhinosol
S 1320
S-1320
S1286_Selleck
SAM002699898
SMR000058337
SPBio_000586
SPBio_002396
SPECTRUM1500813
ST51039033
Spectrum2_000623
Spectrum3_000620
Spectrum4_000821
Spectrum5_001738
Spirocort
TL8003397
Tridesilon
UDB
UNII-168L5HT37P
UNII-2HI1006KPH
UNII-Q3OKS62Q6X
Unit dose budesonide
ZINC03938751
ZINC04097286
budesonide
2HormonesPhase 313979
3Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 312767
4Peripheral Nervous System AgentsPhase 322776
5Anti-Asthmatic AgentsPhase 33369
6Hormone AntagonistsPhase 312778
7Respiratory System AgentsPhase 34818
8glucocorticoidsPhase 34920
9Anti-Inflammatory AgentsPhase 310355
10Autonomic AgentsPhase 39774
11Bronchodilator AgentsPhase 32856
12MesalaminePhase 316089-57-6
13Anti-Inflammatory Agents, Non-SteroidalPhase 34295
14Antirheumatic AgentsPhase 310627
15AnalgesicsPhase 311287
16Analgesics, Non-NarcoticPhase 36260
17Pharmaceutical Solutions7793
18Gastrointestinal Agents8109
19
Bismuth1297440-69-916682734, 105143
Synonyms:
17034_FLUKA
24267-48-9
25243-76-9
264008_ALDRICH
265462_ALDRICH
265470_ALDRICH
452386_ALDRICH
556130_ALDRICH
7440-69-9
83Bi
95372_ALDRICH
95372_FLUKA
95375_FLUKA
AC1NSDYX
AC1O4PN8
AR-1I0647
BISMUTH, 99.95%
 
BISMUTH, 99.999%
Bi
Bismut
Bismuth standard for AAS
Bismuth standard for ICP
Bismuth(III) nitrate solution
Bismuth, elemental
Bismuth-209
C15471
CHEBI:33301
CID5359367
EINECS 231-177-4
HSDB 2078
LS-44708
LTBB002773
MolPort-003-925-759
Wismut
bismuth
bismuto
20Anti-Ulcer Agents1767
21Antacids1767
22ColaNutraceutical1881

Interventional clinical trials:

idNameStatusNCT IDPhase
1Long-Term Treatment of Collagenous Colitis With BudesonideUnknown statusNCT00139165Phase 3
2Budesonide for Maintenance Treatment of Collagenous ColitisCompletedNCT00180076Phase 3
3Budesonide Capsules vs. Mesalazine Granules vs. Placebo in Collagenous ColitisCompletedNCT00450086Phase 3
4SOIBD Collagenous Colitis Maintenance StudyCompletedNCT01278082Phase 3
5Case-Control Study to Identify Risk Factors for Microscopic ColitisCompletedNCT01928667
6Usefulness of Chromoendoscopy in Diagnosing Microscopic ColitisRecruitingNCT01504048
7Treatment of Microscopic ColitisTerminatedNCT00184171

Search NIH Clinical Center for Collagenous Colitis


Cochrane evidence based reviews: colitis, collagenous

Genetic Tests for Collagenous Colitis

About this section

Anatomical Context for Collagenous Colitis

About this section

MalaCards organs/tissues related to Collagenous Colitis:

35
Colon, Small intestine, T cells, Endothelial, Kidney, Heart, Liver

Animal Models for Collagenous Colitis or affiliated genes

About this section

Publications for Collagenous Colitis

About this section

Articles related to Collagenous Colitis:

(show top 50)    (show all 436)
idTitleAuthorsYear
1
Anti-PD1-induced collagenous colitis in a melanoma patient. (26990271)
2016
2
Pseudomembranes Carpet the Right Colon as a Result of Collagenous Colitis. (27725290)
2016
3
Fecal stream diversion and mucosal cytokine levels in collagenous colitis: A case report. (26019474)
2015
4
Collagenous Colitis Associated with Rabeprazole in a Peritoneal Dialysis Patient. (26450480)
2015
5
Acute onset collagenous colitis with unique endoscopic findings. (25610672)
2014
6
Clinical characteristics of collagenous colitis with linear ulcerations. (23560988)
2014
7
Computer aided measurement of sub-epithelial collagen band in colon biopsies for collagenous colitis diagnosis. (23200274)
2013
8
A case of lansoprazole-associated collagenous colitis with longitudinal ulcer. (23539406)
2013
9
Extracolonic gastrointestinal tract morphologic findings in a case of pseudomembranous collagenous colitis. (22658854)
2013
10
Collagenous colitis with mucosal tears in two proton pump inhibitors and non-steroidal naive patients who developed metachronous cancer. (23134231)
2013
11
An epidemiological study of collagenous colitis in southern Sweden from 2001-2010. (22719191)
2012
12
Is smoking a risk factor for collagenous colitis? (21854096)
2011
13
Fecal eosinophil cationic protein as a marker of active disease and treatment outcome in collagenous colitis: a pilot study. (21557718)
2011
14
Systemic sclerosis and collagenous colitis in a patient with retroperitoneal fibrosis. (21453186)
2011
15
Connective tissue growth factor expression is increased in collagenous colitis and coeliac disease. (20840672)
2010
16
NSAID-induced collagenous colitis. (21041266)
2010
17
Mucosal tear in collagenous colitis. (18691941)
2009
18
Lansoprazole-associated collagenous colitis: unique presentation, similar to ischemic colitis. (19866430)
2009
19
Interventions for treating collagenous colitis. (18425892)
2008
20
Colonic perforation as a complication of collagenous colitis in a series of 12 patients. (18702648)
2008
21
Linear mucosal defect may be characteristic of lansoprazole-associated collagenous colitis. (18513560)
2008
22
Collagenous colitis in a Japanese woman: successful treatment with mesalazine. (18577853)
2008
23
Collagenous colitis: oral low-dose methotrexate for patients with difficult symptoms: long-term outcomes. (17845686)
2007
24
Collagenous colitis and eosinophilic gastritis in a 4-year old girl: a case report and review of the literature. (17718794)
2007
25
Detection of inflammatory markers in stools from patients with irritable bowel syndrome and collagenous colitis. (16373277)
2006
26
Interventions for treating collagenous colitis: a Cochrane Inflammatory Bowel Disease Group systematic review of randomized trials. (15571596)
2004
27
Fractured colon: an endoscopically distinctive lesion associated with colonic perforation following colonoscopy in patients with collagenous colitis. (15087693)
2004
28
Association of common variable immunodeficiency with atypical collagenous colitis. (12923382)
2003
29
Further report of familial occurrence of collagenous colitis. (12374242)
2002
30
Budesonide in collagenous colitis: a double-blind placebo-controlled trial with histologic follow-up. (11781276)
2002
31
Histamine content and histamine secretion of the colonic mucosa in patients with collagenous colitis. (12013399)
2002
32
A family with collagenous colitis, ulcerative colitis, and Crohn's disease. (11151908)
2000
33
Microscopic and collagenous colitis in treated celiac disease due to food allergy? (10029639)
1999
34
Collagenous colitis: a long-term follow-up study. (10755251)
1999
35
Olsalazine in collagenous colitis. (8031693)
1994
36
Collagenous colitis: an unusual endoscopic appearance. (8495846)
1993
37
Unusual endoscopic appearance of collagenous colitis. (8409306)
1993
38
Collagenous colitis in children. (8335221)
1993
39
Sequential histologic evaluations in collagenous colitis. Correlations with disease behavior and sampling strategy. (1361906)
1992
40
Diarrhoea caused by collagenous colitis. (2774620)
1989
41
Collagenous colitis. (3337067)
1988
42
Increased subepithelial collagen deposition is not specific for collagenous colitis. (3237709)
1988
43
Collagenous colitis with rapid response to sulphasalazine. (2901742)
1988
44
Collagenous colitis: physiologic and histopathologic studies in seven patients. (3789577)
1987
45
Chronic colitis with thickening of the subepithelial collagen layer (collagenous colitis): histopathologic findings in 15 patients. (3610134)
1987
46
Microscopic and collagenous colitis: different names for the same condition? (3770384)
1986
47
Collagenous colitis--a relapsing and remitting disease. (3699568)
1986
48
Collagenous colitis: the clinical and morphological features. (7122380)
1982
49
Collagenous colitis: a distinctive and potentially reversible disorder. (7068925)
1982
50
Collagenous colitis: a case report and review of the literature. (7155639)
1982

Variations for Collagenous Colitis

About this section

Expression for genes affiliated with Collagenous Colitis

About this section
Search GEO for disease gene expression data for Collagenous Colitis.

Pathways for genes affiliated with Collagenous Colitis

About this section

GO Terms for genes affiliated with Collagenous Colitis

About this section

Cellular components related to Collagenous Colitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1secretory granuleGO:00301419.4CHGA, CHGB, MPO
2extracellular spaceGO:00056158.4CHGA, COL14A1, MPO, RNASE3, SCG2

Biological processes related to Collagenous Colitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1innate immune response in mucosaGO:000222710.0NOS2, RNASE3
2hydrogen peroxide catabolic processGO:004274410.0EPX, MPO
3defense response to Gram-positive bacteriumGO:00508309.7CHGA, RNASE3
4defense response to fungusGO:00508329.5CHGA, MPO
5defense response to Gram-negative bacteriumGO:00508299.4CHGA, NOS2

Molecular functions related to Collagenous Colitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1peroxidase activityGO:000460110.1EPX, MPO
2heme bindingGO:00200379.2EPX, MPO, NOS2

Sources for Collagenous Colitis

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet