BDC
MCID: CLL002
MIFTS: 45

Collecting Duct Carcinoma (BDC) malady

Categories: Rare diseases, Nephrological diseases, Cancer diseases

Aliases & Classifications for Collecting Duct Carcinoma

Aliases & Descriptions for Collecting Duct Carcinoma:

Name: Collecting Duct Carcinoma 12 50 56 14
Renal Medullary Carcinoma 12 50 56
Collecting Duct Carcinoma of the Kidney 50 69
Kidney Medullary Carcinoma 50 69
Bellini Duct Carcinoma 50 56
Bellini Carcinoma 50 56
Bdc 50 56
Cdc 50 56
Renal Carcinoma, Collecting Duct Type 12
Carcinoma of Renal Collecting Duct 12
Renal Collecting Duct Carcinoma 50
Bellini’s Duct Carcinoma 50

Characteristics:

Orphanet epidemiological data:

56
collecting duct carcinoma
Inheritance: Not applicable; Age of onset: Adult;

Classifications:

Orphanet: 56  
Rare renal diseases


External Ids:

Disease Ontology 12 DOID:4464
MeSH 42 D002292
NCIt 47 C6194
SNOMED-CT 64 128669006
ICD10 via Orphanet 34 C64
MESH via Orphanet 43 D002292
UMLS via Orphanet 70 C1266044
UMLS 69 C1266044

Summaries for Collecting Duct Carcinoma

NIH Rare Diseases : 50 collecting duct carcinoma (cdc) is a rare and aggressive form of kidney cancer that begins in the collecting duct of the kidney. many people with cdc have no signs or symptoms until the cancer is at an advanced stage. symptoms may include flank pain, unexplained weight loss, or blood in the urine. although it can affect people of all ages, cdc tends to occur in younger patients. the exact cause of cdc is unknown. it usually occurs in people with no family history of the condition. treatment options for cdc may include surgery and/or chemotherapy. last updated: 3/28/2016

MalaCards based summary : Collecting Duct Carcinoma, also known as renal medullary carcinoma, is related to sarcomatoid renal cell carcinoma and renal cell carcinoma, and has symptoms including flank pain An important gene associated with Collecting Duct Carcinoma is SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily B, Member 1). The drugs Bexxar and Unituxin have been mentioned in the context of this disorder. Affiliated tissues include kidney, b cells and bone, and related phenotypes are homeostasis/metabolism and embryo

Disease Ontology : 12 Collecting duct carcinoma is a renal cell carcinoma described as a rare and aggressive type of renal cell carcinoma. The cancerous cells form irregular tubes inside the tumor. Collecting duct carcinoma is more common among young people and unfortunately is diagnosed in most cases when the cancer has metastasized (spread inside the body).

Wikipedia : 71 Collecting duct carcinoma (CDC) (also known as Bellini duct carcinoma), is a type of kidney cancer that... more...

Related Diseases for Collecting Duct Carcinoma

Diseases related to Collecting Duct Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 119)
id Related Disease Score Top Affiliating Genes
1 sarcomatoid renal cell carcinoma 29.1 FHIT MME PBRM1 SETD2 VIM
2 renal cell carcinoma 11.5
3 brachydactyly, type c 11.1
4 chikungunya 11.0
5 renal cell carcinoma, papillary 11.0
6 bazex syndrome 10.8
7 conotruncal heart malformations 10.8
8 hereditary angioedema 10.8
9 epidermolytic ichthyosis 10.8
10 pancreatitis, hereditary 10.6
11 porphyria, acute hepatic 10.6
12 citrullinemia 10.6
13 carney complex variant 10.6
14 dravet syndrome 10.6
15 anogenital venereal wart 10.6
16 rabies 10.6
17 tetanus 10.6
18 duane retraction syndrome 10.6
19 hantavirus pulmonary syndrome 10.6
20 ebola hemorrhagic fever 10.6
21 folliculitis 10.6
22 toxocariasis 10.6
23 acute flaccid myelitis 10.6
24 neurosyphilis 10.6
25 nodding syndrome 10.6
26 zika virus infection 10.6
27 myxopapillary ependymoma 10.2 SMARCB1 VIM
28 progressive multifocal leukoencephalopathy 10.2 AMACR VIM
29 progeria 10.2 PAX8 VIM
30 spastic ataxia 5 10.2 PAX8 VIM
31 klinefelter's syndrome 10.2 PAX8 VIM
32 liver angiosarcoma 10.2 MME VIM
33 uterine hypoplasia 10.2 MME VIM
34 lymphangiosarcoma 10.2 MME VIM
35 superficial urinary bladder cancer 10.2 AMACR PAX8
36 lung benign neoplasm 10.2 SMARCB1 VIM
37 sebaceous adenoma 10.2 MME VIM
38 conjunctival intraepithelial neoplasm 10.1 MME PAX8
39 subareolar duct papillomatosis 10.1 MME PAX8
40 renal pelvis carcinoma 10.1 AMACR PAX8
41 thymus gland disease 10.1 AMACR PAX8
42 pericardial mesothelioma 10.1 PBRM1 SMARCB1 VIM
43 fuchs' heterochromic uveitis 10.1 AMACR PAX8
44 pilar sheath acanthoma 10.1 MME VIM
45 cleft palate cardiac defect ectrodactyly 10.1 PBRM1 SETD2
46 cranial nerve disease 10.1 MME PAX8
47 scirrhous adenocarcinoma 10.1 AMACR VIM
48 sarcomatoid mesothelioma 10.1 AMACR MME
49 van regemorter pierquin vamos syndrome 10.1 MME SMARCB1
50 ovarian brenner tumor 10.0 FHIT PBRM1 SETD2

Graphical network of the top 20 diseases related to Collecting Duct Carcinoma:



Diseases related to Collecting Duct Carcinoma

Symptoms & Phenotypes for Collecting Duct Carcinoma

UMLS symptoms related to Collecting Duct Carcinoma:


flank pain

MGI Mouse Phenotypes related to Collecting Duct Carcinoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.76 AMACR FHIT MME OCRL PAX8 SETD2
2 embryo MP:0005380 9.65 PAX8 PBRM1 SETD2 SMARCB1 VIM
3 mortality/aging MP:0010768 9.56 AMACR FHIT OCRL PAX8 PBRM1 SETD2
4 vision/eye MP:0005391 9.02 OCRL PAX8 SETD2 SMARCB1 VIM

Drugs & Therapeutics for Collecting Duct Carcinoma

FDA approved drugs:

id Drug Name Active Ingredient(s) 17 Company Approval Date
1
Bexxar 17 46 TOSITUMOMAB; IODINE I 131 TOSITUMOMAB Corixa Approved June 2003
2
Unituxin 17 46 DINUTUXIMAB United Therapeutics Approved March 2015

Drugs for Collecting Duct Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 171)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tamoxifen Approved Phase 3,Phase 2 10540-29-1 2733526
2
Oxybutynin Approved, Investigational Phase 3 5633-20-5 4634
3
Anastrozole Approved, Investigational Phase 3 120511-73-1 2187
4
Exemestane Approved, Investigational Phase 3 107868-30-4 60198
5
Letrozole Approved, Investigational Phase 3 112809-51-5 3902
6 Calcium, Dietary Phase 3,Phase 1,Phase 2
7 Calcimimetic Agents Phase 3
8 Cinacalcet Hydrochloride Phase 3
9 Hormone Antagonists Phase 3,Phase 2,Phase 1
10 Hormones Phase 3,Phase 2,Phase 1
11 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
12 Anti-Infective Agents Phase 3,Phase 1,Phase 2
13 Peripheral Nervous System Agents Phase 3,Phase 1,Phase 2
14 Anticoagulants Phase 3,Phase 2
15 Antineoplastic Agents, Hormonal Phase 3,Phase 2
16 Bone Density Conservation Agents Phase 3,Phase 2
17 Chelating Agents Phase 3,Phase 2
18 Estrogen Antagonists Phase 3,Phase 2
19 Estrogen Receptor Modulators Phase 3,Phase 2
20 Estrogens Phase 3,Phase 2
21 Selective Estrogen Receptor Modulators Phase 3,Phase 2
22 Autonomic Agents Phase 3
23 Cholinergic Agents Phase 3
24 Cholinergic Antagonists Phase 3
25 Mandelic Acids Phase 3
26 Muscarinic Antagonists Phase 3
27 Neurotransmitter Agents Phase 3
28 Parasympatholytics Phase 3
29 Renal Agents Phase 3
30 Aromatase Inhibitors Phase 3
31 Steroid Synthesis Inhibitors Phase 3
32 Citrate Nutraceutical Phase 3,Phase 2
33
Citric Acid Nutraceutical, Vet_approved Phase 3,Phase 2 77-92-9 311
34
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
35
Loperamide Approved Phase 1, Phase 2 53179-11-6 3955
36
Fluvastatin Approved Phase 2 93957-54-1 1548972
37
Carboplatin Approved Phase 2,Phase 1 41575-94-4 10339178 498142 38904
38
Paclitaxel Approved, Vet_approved Phase 2,Phase 1 33069-62-4 36314
39
chloroquine Approved, Vet_approved Phase 1, Phase 2 54-05-7 2719
40
Cyclophosphamide Approved, Investigational Phase 2 50-18-0, 6055-19-2 2907
41
Melphalan Approved Phase 2 148-82-3 4053 460612
42
Thiotepa Approved Phase 2 52-24-4 5453
43
Trastuzumab Approved, Investigational Phase 2,Phase 1 180288-69-1 9903
44
Bevacizumab Approved, Investigational Phase 2 216974-75-3
45
Histamine Approved, Investigational Phase 1, Phase 2 75614-87-8, 51-45-6 774
46
Salmon Calcitonin Approved, Investigational Phase 2,Phase 1 47931-85-1 16129616
47
Everolimus Approved Phase 2,Phase 1 159351-69-6 6442177
48
Miconazole Approved, Investigational, Vet_approved Phase 2,Phase 1 22916-47-8 4189
49
Sirolimus Approved, Investigational Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
50
Gemcitabine Approved Phase 2,Phase 1 95058-81-4 60750

Interventional clinical trials:

(show top 50) (show all 73)
id Name Status NCT ID Phase
1 Electronic Xoft Intersociety Brachytherapy Trial: Electronic Brachytherapy (EBT) For Treatment of Early Stage Breast Cancer Completed NCT00742222 Phase 4
2 Genetic Counseling or Usual Care in Helping Women With Newly Diagnosed Ductal Carcinoma In Situ or Stage I, Stage II, or Stage IIIA Breast Cancer Make Treatment Decisions Completed NCT00262899 Phase 3
3 Cinacalcet to Treat Familial Primary Hyperparathyroidism Completed NCT00325104 Phase 3
4 Oxybutynin Chloride in Managing Hot Flashes Recruiting NCT02961790 Phase 3
5 Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer Recruiting NCT01272037 Phase 3
6 Trial Of Sunitinib In Advanced Non-Clear Cell Type Renal Cell Carcinoma Unknown status NCT01219751 Phase 2
7 The Efficacy of CASAD in Patients With Diarrhea Related to Medullary Thyroid Cancer Unknown status NCT01739634 Phase 1, Phase 2
8 Sunitinib Malate in Patients With Non-Clear Cell Renal Cell Cancer Completed NCT00465179 Phase 2
9 Effect of Fluvastatin on Biomarkers in Women Who Are Undergoing Surgery for Ductal Carcinoma In Situ or Stage I Breast Cancer Completed NCT00416403 Phase 2
10 Paclitaxel and Carboplatin in Treating Patients With Locally Advanced or Metastatic Renal Cell Cancer Completed NCT00077129 Phase 2
11 Study of the Efficacy of Chloroquine in the Treatment of Ductal Carcinoma in Situ (The PINC Trial) Completed NCT01023477 Phase 1, Phase 2
12 4-Hydroxytamoxifen or Tamoxifen Citrate in Treating Women With Newly Diagnosed Ductal Breast Carcinoma in Situ Completed NCT00952731 Phase 2
13 Combination Chemotherapy With or Without Trastuzumab Followed By an Autologous Stem Cell Transplant and Radiation Therapy in Treating Patients With Stage III or Stage IV Breast Cancer Completed NCT00182793 Phase 2
14 EPO906 Therapy in Patients With Advanced Kidney Cancer Completed NCT00035243 Phase 2
15 Bevacizumab and Erlotinib Hydrochloride in Treating Patients With Metastatic or Unresectable Biliary Tumors Completed NCT00356889 Phase 2
16 ImmunoTEP for Patients With Medullary Thyroid Carcinoma. Completed NCT01730638 Phase 1, Phase 2
17 Phase II Two-step Radioimmunotherapy Clinical Study in Medullary Thyroid Carcinoma Completed NCT00467506 Phase 2
18 Study of Gemcitabine+Platinium Salt+Bevacizumab Combination for Metastatic Collecting Duct Carcinoma (BEVABEL) Recruiting NCT02363751 Phase 2
19 Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney Cancer Recruiting NCT01767636 Phase 2
20 Conjugated Estrogens/Bazedoxifene in Treating Patients With Ductal Carcinoma in Situ Undergoing Surgery Recruiting NCT02694809 Phase 2
21 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
22 A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma Recruiting NCT02601950 Phase 2
23 Study for the Evaluation of Efficacy of Pembrolizumab (MK-3475) in Patients With Rare Tumors Recruiting NCT02721732 Phase 2
24 Study of LOXO-101 (Larotrectinib) in Subjects With NTRK Fusion Positive Solid Tumors (NAVIGATE) Recruiting NCT02576431 Phase 2
25 Sorafenib Combined With Chemotherapy for Renal Collecting Duct Carcinoma Active, not recruiting NCT01762150 Phase 2
26 Everolimus Versus Sunitinib in Non-Clear Cell Renal Cell Carcinoma Active, not recruiting NCT01185366 Phase 2
27 Open Label Study to Evaluate Efficacy and Long Term Safety of LUM001 in the Treatment of Cholestatic Liver Disease in Patients With Progressive Familial Intrahepatic Cholestasis Active, not recruiting NCT02057718 Phase 2
28 Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer Active, not recruiting NCT00027820 Phase 1, Phase 2
29 Cabozantinib for Advanced Urothelial Cancer Active, not recruiting NCT01688999 Phase 2
30 Pasireotide & Everolimus in Adult Patients With Radioiodine-Refractory Differentiated & Medullary Thyroid Cancer Active, not recruiting NCT01270321 Phase 2
31 177Lutetium-DOTA-Octreotate Therapy in Somatostatin Receptor-Expressing Neuroendocrine Neoplasms Active, not recruiting NCT01237457 Phase 2
32 A Study of Atezolizumab in Participants With Programmed Death - Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer Active, not recruiting NCT02031458 Phase 2
33 Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors Not yet recruiting NCT02867592 Phase 2
34 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) Completed NCT00031681 Phase 1
35 Liposomal Doxorubicin Before Mastectomy in Treating Women With Invasive Breast Cancer Completed NCT00290732 Phase 1
36 Study of XL184 (Cabozantinib) in Adults With Advanced Malignancies Completed NCT00215605 Phase 1
37 NGR-TNF in Treating Patients With Advanced Solid Tumors Completed NCT00098943 Phase 1
38 Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu Completed NCT00004074 Phase 1
39 Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors Completed NCT01155258 Phase 1
40 Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer Completed NCT00005842 Phase 1
41 A Phase 1 Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma Recruiting NCT02601937 Phase 1
42 177Lu-PP-F11N for Receptor Targeted Therapy and Imaging of Metastatic Thyroid Cancer. Recruiting NCT02088645 Phase 1
43 Gemcitabine Hydrochloride, Oxaliplatin, and Erlotinib Hydrochloride in Treating Patients With Advanced Biliary Tract Cancer, Pancreatic Cancer, Duodenal Cancer, or Ampullary Cancer Active, not recruiting NCT00987766 Phase 1
44 Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors Active, not recruiting NCT00655655 Phase 1
45 Topical MTS-01 for Dermatitis During Radiation and Chemotherapy for Anal Cancer Terminated NCT01324141 Phase 1
46 Veliparib, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced Biliary, Pancreatic, Urothelial, or Non-Small Cell Lung Cancer Terminated NCT01282333 Phase 1
47 Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer Terminated NCT00002947 Phase 1
48 Study of Biomarkers in Blood and/or Tumor Tissue Samples From Patients With Ductal Carcinoma in Situ and From Healthy Volunteers Unknown status NCT00935233
49 LUDEC Study - Pilot Study of the Lavage of the Uterine Cavity for the Diagnosis of Endometrial Carcinoma Unknown status NCT02387645
50 Studying Cells Collected Through Ductal Lavage in Women Undergoing Surgery for Ductal Carcinoma In Situ or Other Breast Cancer Completed NCT00896857

Search NIH Clinical Center for Collecting Duct Carcinoma

Genetic Tests for Collecting Duct Carcinoma

Anatomical Context for Collecting Duct Carcinoma

MalaCards organs/tissues related to Collecting Duct Carcinoma:

39
Kidney, B Cells, Bone, Thyroid, Salivary Gland

Publications for Collecting Duct Carcinoma

Articles related to Collecting Duct Carcinoma:

(show top 50) (show all 124)
id Title Authors Year
1
Sarcomatoid Renal Cell Carcinoma and Collecting Duct Carcinoma: Discrimination From Common Renal Cell Carcinoma Subtypes and Benign RCC Mimics on Multiphasic MDCT. ( 28528853 )
2017
2
Targeted Therapy in Collecting Duct Carcinoma of the Kidney: A Case Report and Literature Review. ( 26684811 )
2016
3
Enhanced MRI and 18F-FDG PET/CT Findings of Preoperative Primary Renal Collecting Duct Carcinoma. ( 27775947 )
2016
4
A renal adenocarcinoma in a corn snake (Pantherophis guttatus) resembling human collecting duct carcinoma. ( 27493139 )
2016
5
Collecting duct carcinoma of the kidney is associated with CDKN2A deletion and SLC family gene up-regulation. ( 27144525 )
2016
6
Collecting Duct Carcinoma With Cardiac Metastases: A Case Report &A Literature Review. ( 26977410 )
2016
7
Anti-programmed Death Receptor 1 Blockade Induces Clinical Response in a Patient With Metastatic Collecting Duct Carcinoma. ( 27021586 )
2016
8
Comparative study of CT appearances in mucinous tubular and spindle cell carcinoma and collecting duct carcinoma of the kidney. ( 26435393 )
2015
9
Collecting duct carcinoma of the kidney: A case report. ( 26137167 )
2015
10
Papillary renal cell carcinoma and collecting duct carcinoma combination. A case report and review of synchronous renal cell carcinoma subtypes in the same kidney. ( 26170866 )
2015
11
Retraction Note: Collecting duct carcinoma of the kidney: a clinicopathological study of five cases. ( 25884188 )
2015
12
Characterization of Clinical Cases of Collecting Duct Carcinoma of the Kidney Assessed by Comprehensive Genomic Profiling. ( 26149668 )
2015
13
Collecting duct carcinoma of the kidney. A contribution of 4 new cases. ( 25306992 )
2014
14
Collision tumor of the kidney composed of clear cell carcinoma and collecting duct carcinoma: report of a case with unusual morphology and clinical follow-up. ( 24589208 )
2014
15
Composite chromophobe renal cell carcinoma with sarcomatoid differentiation containing osteosarcoma, chondrosarcoma, squamous metaplasia and associated collecting duct carcinoma: a case report. ( 25291862 )
2014
16
Clinical features and treatment of collecting duct carcinoma of the kidney from the korean cancer study group genitourinary and gynecology cancer committee. ( 24851105 )
2014
17
Collecting duct carcinoma versus renal medullary carcinoma: an appeal for nosologic and biological clarity. ( 24805860 )
2014
18
A collecting duct carcinoma producing carcinoembryonic antigen and Ca-125 in a 29-year-old woman. ( 24531923 )
2014
19
Collecting duct carcinoma of the kidney: Imaging observations of a rare tumor. ( 24396480 )
2014
20
Treatment of collecting duct carcinoma: current status and future perspectives. ( 24511050 )
2014
21
Management of renal collecting duct carcinoma: a systematic review and the McMaster experience. ( 23737692 )
2013
22
Renal collecting duct carcinoma with extensive coagulative necrosis mimicking anemic infarct: report of a case and the literature review. ( 23866935 )
2013
23
Renal collecting duct carcinoma: report of a case with unusual imaging findings regarding renal function. ( 23771391 )
2013
24
Salivary gland-type renal carcinoma, a subset of collecting duct carcinoma: case report and meta-analysis of the entity. ( 23339365 )
2013
25
Triple combination of bevacizumab, gemcitabine and platinum salt in metastatic collecting duct carcinoma. ( 24190963 )
2013
26
Active targeted therapy for metastatic collecting duct carcinoma of the kidney: a case report and review of the literature. ( 23686671 )
2013
27
Collecting duct carcinoma of the kidney: a clinicopathological study of five cases. ( 23773436 )
2013
28
The MSCT and MRI findings of collecting duct carcinoma. ( 23726725 )
2013
29
The multislice CT findings of renal carcinoma associated with XP11.2 translocation/TFE gene fusion and collecting duct carcinoma. ( 23446748 )
2013
30
Collecting duct carcinoma: a rare malignancy. ( 23575082 )
2013
31
A case report of collecting duct carcinoma of the kidney coexistent with giant adrenal myelolipoma. ( 22511446 )
2012
32
Collecting duct carcinoma presenting uncommon metastatic features. ( 23235769 )
2012
33
Thyroid transcription factor 1 expression in a case of renal collecting duct carcinoma. ( 22703591 )
2012
34
Tubulocystic renal carcinoma (low grade collecting duct carcinoma). ( 23154610 )
2012
35
Collecting duct carcinoma: a rare renal tumor. ( 22805397 )
2012
36
Distal ureteral seeding metastasis of collecting duct carcinoma manifesting as deep vein thrombosis. ( 22513238 )
2012
37
HER2 blockade in metastatic collecting duct carcinoma (CDC) of the kidney: a case report. ( 23207624 )
2012
38
Metastatic collecting duct carcinoma of the kidney treated with sunitinib. ( 21752265 )
2011
39
Immunohistochemical analysis of SMARCB1/INI-1 expression in collecting duct carcinoma. ( 21705046 )
2011
40
Retraction: Metastatic collecting duct carcinoma of the kidney treated with Sunitinib. ( 22024397 )
2011
41
Metastatic collecting duct carcinoma of the kidney responded to sunitinib. ( 20686910 )
2011
42
Undiagnosed collecting duct carcinoma presenting as meningeal carcinomatosis and multiple bone metastases. ( 20686287 )
2010
43
PAX8 (+)/p63 (-) immunostaining pattern in renal collecting duct carcinoma (CDC): a useful immunoprofile in the differential diagnosis of CDC versus urothelial carcinoma of upper urinary tract. ( 20463571 )
2010
44
Inhibition of pleural metastasis of collecting duct carcinoma of the kidney by modified cytokine-induced killer cells: A case report and review of the literature. ( 22870094 )
2010
45
Sarcomatoid collecting duct carcinoma of kidney diagnosed with urine and renal pelvic lavage cytology. ( 20014307 )
2010
46
Genetic alterations and chemosensitivity profile in newly established human renal collecting duct carcinoma cell lines. ( 19154479 )
2009
47
Sorafenib induces therapeutic response in a patient with metastatic collecting duct carcinoma of kidney. ( 19209019 )
2009
48
Influence of demographic factors on outcome of collecting duct carcinoma: a Surveillance, Epidemiology, and End Results (SEER) database analysis. ( 19692318 )
2009
49
Comparison of gene expression profiles in tubulocystic carcinoma and collecting duct carcinoma of the kidney. ( 19390420 )
2009
50
Collecting duct carcinoma with acquired cystic disease of the kidney in a long-term hemodialysis patient. ( 18184183 )
2008

Variations for Collecting Duct Carcinoma

Cosmic variations for Collecting Duct Carcinoma:

9 (show all 21)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA Conf
1 COSM25676 VHL kidney,NS,carcinoma,renal cell c.485G>T p.C162F 30
2 COSM27269 UMPS kidney,NS,carcinoma,renal cell c.528G>A p.L176L 30
3 COSM30474 TRIO kidney,NS,carcinoma,renal cell c.9008A>G p.N3003S 30
4 COSM26594 RNF144A kidney,NS,carcinoma,renal cell c.410C>T p.A137V 30
5 COSM26987 RGS7 kidney,NS,carcinoma,renal cell c.169T>C p.F57L 30
6 COSM26614 RABGAP1 kidney,NS,carcinoma,renal cell c.1533T>A p.H511Q 30
7 COSM30530 PTPN22 kidney,NS,carcinoma,renal cell c.209G>C p.R70P 30
8 COSM27618 KMT2A kidney,NS,carcinoma,renal cell c.5711C>T p.A1904V 30
9 COSM30502 ITPR3 kidney,NS,carcinoma,renal cell c.4574G>T p.C1525F 30
10 COSM28415 DOCK1 kidney,NS,carcinoma,renal cell c.1306G>T p.D436Y 30
11 COSM30531 COPS4 kidney,NS,carcinoma,renal cell c.385G>C p.G129R 30
12 COSM25654 CDC5L kidney,NS,carcinoma,renal cell c.1196G>A p.R399Q 30
13 COSM30471 ARHGAP20 kidney,NS,carcinoma,renal cell c.1355A>G p.D452G 30
14 COSM17957 VHL kidney,NS,carcinoma,renal cell carcinoma unclassified c.292T>G p.Y98D 28
15 COSM17875 VHL kidney,NS,carcinoma,renal cell carcinoma unclassified c.234T>G p.N78K 28
16 COSM14305 VHL kidney,NS,carcinoma,renal cell carcinoma unclassified c.266T>A p.L89H 28
17 COSM17983 VHL kidney,NS,carcinoma,renal cell carcinoma unclassified c.500G>A p.R167Q 28
18 COSM14312 VHL kidney,NS,carcinoma,renal cell carcinoma unclassified c.353T>C p.L118P 28
19 COSM14425 VHL kidney,NS,carcinoma,renal cell carcinoma unclassified c.341-2A>T p.? 28
20 COSM14382 VHL kidney,NS,carcinoma,renal cell carcinoma unclassified c.245G>C p.R82P 28
21 COSM52899 PBRM1 kidney,NS,carcinoma,renal cell carcinoma unclassified c.3805A>T p.K1269* 28

Expression for Collecting Duct Carcinoma

Search GEO for disease gene expression data for Collecting Duct Carcinoma.

Pathways for Collecting Duct Carcinoma

GO Terms for Collecting Duct Carcinoma

Cellular components related to Collecting Duct Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 BAF-type complex GO:0090544 8.62 PBRM1 SMARCB1

Biological processes related to Collecting Duct Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.63 FHIT LZTS1 PAX8 PBRM1 SETD2 SMARCB1
2 covalent chromatin modification GO:0016569 9.13 PBRM1 SETD2 SMARCB1
3 transcription, DNA-templated GO:0006351 9.1 FHIT LZTS1 PAX8 PBRM1 SETD2 SMARCB1

Sources for Collecting Duct Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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