BDC
MCID: CLL002
MIFTS: 44

Collecting Duct Carcinoma (BDC) malady

Rare diseases, Nephrological diseases, Cancer diseases categories

Summaries for Collecting Duct Carcinoma

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Sources:
9Disease Ontology, 66Wikipedia, 34MalaCards
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Disease Ontology:9 Collecting duct carcinoma is a renal cell carcinoma described as a rare and aggressive type of renal cell carcinoma. the cancerous cells form irregular tubes inside the tumor. collecting duct carcinoma is more common among young people and unfortunately is diagnosed in most cases when the cancer has metastasized (spread inside the body).

MalaCards: Collecting Duct Carcinoma, also known as collecting duct carcinoma of the kidney, is related to renal cell carcinoma and hepatitis. An important gene associated with Collecting Duct Carcinoma is LZTS1 (leucine zipper, putative tumor suppressor 1). The compounds forskolin and oligonucleotide have been mentioned in the context of this disorder. Affiliated tissues include kidney, bone and thyroid, and related mouse phenotypes are renal/urinary system and growth/size/body.

Wikipedia:66 Bellini duct carcinoma (BDC, also known as low-grade collecting duct carcinoma and tubulocystic... more...

Aliases & Classifications for Collecting Duct Carcinoma

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9Disease Ontology, 44NIH Rare Diseases, 11DISEASES, 50Orphanet, 63UMLS, 41NCIt, 59SNOMED-CT, 36MeSH, 60SNOMED-CT via Orphanet, 64UMLS via Orphanet, 37MESH via Orphanet, 27ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Nephrological diseases


Characteristics (Orphanet epidemiological data):

50
collecting duct carcinoma:
Inheritance: Sporadic; Age of onset: Adulthood


Aliases & Descriptions:

collecting duct carcinoma 9 44 11 50
collecting duct carcinoma of the kidney 44 63
renal medullary carcinoma 9 50
cdc 44 50
renal carcinoma, collecting duct type 9
carcinoma of renal collecting duct 9
renal collecting duct carcinoma 44
bellini duct carcinoma 50
brachydactyly type c 63
bellini carcinoma 50
bdc 50


External Ids:

Disease Ontology9 DOID:4464
NCIt41 C7572, C6194
MeSH36 D002292
SNOMED-CT via Orphanet60 128669006
SNOMED-CT59 128669006
UMLS via Orphanet64 C1266044
MESH via Orphanet37 D002292
ICD10 via Orphanet27 C64

Related Diseases for Collecting Duct Carcinoma

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Collecting Duct Carcinoma:



Diseases related to collecting duct carcinoma

Symptoms for Collecting Duct Carcinoma

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Drugs & Therapeutics for Collecting Duct Carcinoma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Collecting Duct Carcinoma

Drug clinical trials:

Search ClinicalTrials for Collecting Duct Carcinoma

Search NIH Clinical Center for Collecting Duct Carcinoma

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Genetic Tests for Collecting Duct Carcinoma

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Anatomical Context for Collecting Duct Carcinoma

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34MalaCards
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MalaCards organs/tissues related to Collecting Duct Carcinoma:

34
Kidney, Bone, Thyroid, Salivary gland

Animal Models for Collecting Duct Carcinoma or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Collecting Duct Carcinoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.5PAX8, AQP3, OCRL
2MP:00053788.0PAX8, AQP3, AMACR, OCRL
3MP:00107688.0PAX8, AQP3, AMACR, OCRL
4MP:00053767.7OCRL, AMACR, AQP3, PAX8

Publications for Collecting Duct Carcinoma

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Sources:
53PubMed
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Articles related to Collecting Duct Carcinoma:

(show top 50)    (show all 103)
idTitleAuthorsYear
1
Collecting duct carcinoma of the kidney: Imaging observations of a rare tumor. (24396480)
2014
2
Triple combination of bevacizumab, gemcitabine and platinum salt in metastatic collecting duct carcinoma. (24190963)
2013
3
Renal collecting duct carcinoma: report of a case with unusual imaging findings regarding renal function. (23771391)
2013
4
Renal collecting duct carcinoma with extensive coagulative necrosis mimicking anemic infarct: report of a case and the literature review. (23866935)
2013
5
Active targeted therapy for metastatic collecting duct carcinoma of the kidney: a case report and review of the literature. (23686671)
2013
6
The MSCT and MRI findings of collecting duct carcinoma. (23726725)
2013
7
Thyroid transcription factor 1 expression in a case of renal collecting duct carcinoma. (22703591)
2012
8
Collecting duct carcinoma: a rare renal tumor. (22805397)
2012
9
A case report of collecting duct carcinoma of the kidney coexistent with giant adrenal myelolipoma. (22511446)
2012
10
Tubulocystic renal carcinoma (low grade collecting duct carcinoma). (23154610)
2012
11
Metastatic collecting duct carcinoma of the kidney responded to sunitinib. (20686910)
2011
12
Sarcomatoid collecting duct carcinoma of kidney diagnosed with urine and renal pelvic lavage cytology. (20014307)
2010
13
Renal collecting duct carcinoma in a dog. (18587095)
2008
14
Renal collecting duct carcinoma and concomitant bladder urothelial carcinoma: a case report. (18364277)
2008
15
Collecting duct carcinoma: an incidental finding in a non functional kidney secondary to nephrolithiasis. (17432025)
2007
16
Sarcomatoid collecting-duct carcinoma of the kidney. (18272028)
2007
17
Collecting duct carcinoma associated with renal stones]. (17373248)
2007
18
Collecting duct carcinoma arising from multicystic dysplastic kidney disease. (18947667)
2006
19
Collecting duct carcinoma of kidney producing alpha-fetoprotein. (16126361)
2005
20
Synchronous collecting duct carcinoma and papillary renal cell carcinoma: a case report and review of the literature. (15816631)
2005
21
Low-grade renal collecting duct carcinoma. A case report with histochemical, immunohistochemical, and ultrastructural study. (15692951)
2005
22
Cortically located collecting duct carcinoma. (15922425)
2005
23
Collecting duct carcinoma: an entity to be redefined? (15480763)
2004
24
Fine needle aspiration cytology of collecting duct carcinoma of the kidney: report of a case with distinctive features and differential diagnosis. (15581171)
2004
25
Collecting duct carcinoma of the kidney with retroperitoneal lymph mass. (15074793)
2004
26
Collecting duct carcinoma of the kidney: a clinicopathological study of 9 cases. (14501710)
2003
27
New cytological findings on fine-needle aspiration of renal collecting duct carcinoma. (14506682)
2003
28
The collecting duct carcinoma of the kidney: a cytogenetical study. (12767370)
2003
29
Immunohistochemical study of bcl-2, p53 and Ki-67 expressions in collecting duct carcinoma of the kidney. Five cases and review of the literature on bcl-2, p53 and Ki-67 expressions in renal cell carcinoma and transitional cell carcinoma. (12119441)
2002
30
Active chemotherapy for collecting duct carcinoma of the kidney: a case report and review of the literature. (11815966)
2002
31
Collecting duct carcinoma with long survival treated by partial nephrectomy. (11442664)
2001
32
A case of collecting duct carcinoma (Bellini duct carcinoma) producing carcinoembryonic antigen]. (11329960)
2001
33
Long-term remission in a patient with metastatic collecting duct carcinoma treated with taxol/carboplatin and surgery. (11744492)
2001
34
Collecting duct carcinoma of the kidney: are imaging findings suggestive of the diagnosis? (11222193)
2001
35
Renal collecting duct carcinoma. Report of a case with cytologic findings on fine needle aspiration. (10833995)
2000
36
Collecting duct carcinoma arising in a solitary kidney: imaging findings. (10416089)
1999
37
Bellini duct (collecting duct) carcinoma of the kidney. (10195859)
1998
38
Low-grade collecting duct carcinoma of the kidney: report of 13 cases of low-grade mucinous tubulocystic renal carcinoma of possible collecting duct origin. (9372874)
1997
39
Collecting-duct carcinoma presenting as upper tract lesion with abnormal urine cytology. (9099549)
1997
40
Bellini duct (collecting duct) carcinoma of the kidney. (8677593)
1996
41
Cytopathology of retrograde renal pelvis brush specimens: an analysis of 40 cases with emphasis on collecting duct carcinoma and low-intermediate grade transitional cell carcinoma. (8982587)
1996
42
Collecting duct carcinoma. An unusual renal tumour. (8936632)
1996
43
Collecting duct carcinoma of kidney: a cytological study and case report. (8872437)
1996
44
Cytologic findings of collecting duct carcinoma of the kidney. (8599913)
1995
45
Renal collecting duct carcinoma. Report of a case with urinary cytologic findings. (8091912)
1994
46
Fine-needle aspiration biopsy of renal collecting duct carcinoma. (7956666)
1994
47
Collecting duct carcinoma of the kidney. (8044515)
1994
48
Sarcomatoid collecting duct carcinoma: a clinicopathologic and immunohistochemical study of five cases. (7504649)
1993
49
Collecting duct carcinoma: cytogenetic characterization. (1505933)
1992
50
Collecting duct carcinoma of the kidney. (3542784)
1986

Variations for Collecting Duct Carcinoma

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1 National Center for Biotechnology Information (Clinvar)
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Clinvar genetic disease variations for Collecting Duct Carcinoma:

1
id Gene Name Type Significance SNP ID Assembly Location
1GDF5NM_000557.4(GDF5): c.901C> T (p.Arg301Ter)single nucleotide variantPathogenicrs74315386GRCh37Chr 20, 34022312: 34022312
2GDF5NM_000557.4(GDF5): c.517A> G (p.Met173Val)single nucleotide variantPathogenicrs28936397GRCh37Chr 20, 34025192: 34025192
3GDF5NM_000557.4(GDF5): c.1461T> G (p.Tyr487Ter)single nucleotide variantPathogenicrs121909348GRCh37Chr 20, 34021752: 34021752

Expression for genes affiliated with Collecting Duct Carcinoma

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Collecting Duct Carcinoma

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Pathways for genes affiliated with Collecting Duct Carcinoma

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Compounds for genes affiliated with Collecting Duct Carcinoma

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Sources:
46Novoseek, 52PharmGKB, 12DrugBank
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Compounds related to Collecting Duct Carcinoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1forskolin46 52 1211.4PAX8, AQP3
2oligonucleotide468.5PAX8, AQP3, AMACR
3chloride468.4AQP3, AMACR, OCRL

GO Terms for genes affiliated with Collecting Duct Carcinoma

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Products for genes affiliated with Collecting Duct Carcinoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Collecting Duct Carcinoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet