MCID: CLN015
MIFTS: 41

Colon Adenocarcinoma malady

Summaries for Colon Adenocarcinoma

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Colorectal cancer, also known as colon cancer, rectal cancer, or bowel cancer, is a cancer from... more...

MalaCards: Colon Adenocarcinoma, also known as adenocarcinoma of colon, is related to adenocarcinoma and adenoma. An important gene associated with Colon Adenocarcinoma is RPS3 (ribosomal protein S3). The compounds progesterone and tyrosine have been mentioned in the context of this disorder.

Aliases & Classifications for Colon Adenocarcinoma

Sources:
8Disease Ontology, 45Novoseek, 61UMLS, 40NCIt, 57SNOMED-CT
See all sources

Aliases & Descriptions:

colon adenocarcinoma 8 45
adenocarcinoma of colon 8 61
colonic adenocarcinoma 8


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Disease Ontology8 DOID:234
SNOMED-CT57 255082000
NCIt40 C4349

Related Diseases for Colon Adenocarcinoma

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Colon Adenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 127)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma32.1CEACAM5, CALB2, VIP, RPS3, S100A4, TNFRSF6B
2adenoma30.4CEACAM5, CEACAM7, ACSL4, KRT20, SI, EIF4E
3signet ring cell adenocarcinoma30.3MUC2, KRT20, CEACAM5
4squamous cell carcinoma30.2CALB2, S100A4, AREG, TYMS, MUC2, CDX1
5stomach cancer30.0CDX1, MUC2, TYMS, AREG, TNFRSF6B, S100A4
6colon lymphoma10.3
7submucosal invasive colon adenocarcinoma10.2
8hypoxia10.2
9neuroendocrine carcinoma10.1
10colon squamous cell carcinoma10.1
11chronic myeloid leukemia10.1
12imperforate anus10.1
13mucinous adenocarcinoma10.1
14colon signet ring adenocarcinoma10.1
15ureter adenocarcinoma10.1
16peutz-jeghers syndrome10.1
17colon mucinous adenocarcinoma10.1
18anus adenocarcinoma10.1
19breast adenocarcinoma10.1
20t-cell leukemia10.1
21peutz–jeghers syndrome10.1
22cushing's syndrome10.0
23muir-torre syndrome10.0
24pelger-huet anomaly10.0
25sebaceous adenocarcinoma10.0
26apocrine adenocarcinoma10.0
27colon cancer10.0HPSE, CDX1, MUC2, TYMS, AREG, TNFRSF6B
28colorectal cancer10.0S100A4, AREG, TYMS, MUC2, CDX1, SI
29breast cancer10.0VIP, S100A4, AREG, TYMS, MUC2, HPSE
30hepatocellular carcinoma10.0VIP, TNFRSF6B, AREG, MUC2, HPSE, ACSL4
31gastric adenocarcinoma10.0VIP, S100A4, TYMS, MUC2, KRT20, CEACAM7
32non-small cell lung carcinoma10.0S100A4, AREG, TYMS, MUC2, HPSE, CEACAM7
33malignant mesothelioma10.0CALB2, AREG, TYMS, HPSE, KRT20, CEACAM5
34ovarian cancer10.0VIP, CALB2, AREG, TYMS, HPSE, EIF4E
35prostate cancer10.0VIP, S100A4, AREG, MUC2, HPSE, EIF4E
36melanoma10.0CALB2, S100A4, AREG, HPSE, EIF4E, CEACAM7
37burkitt's lymphoma10.0CALB2, S100A4, TYMS, HPSE, EIF4E, FUT4
38leukemia10.0FUT4, EIF4E, HPSE, TYMS, AREG, RPS3
39lung adenocarcinoma10.0CEACAM5, CEACAM7, KRT20, S100A4, CALB2
40lung small cell carcinoma10.0VIP, CALB2, KRT20, CEACAM7, CEACAM5
41gallbladder cancer10.0CEACAM5, HPSE, MUC2, TYMS
42cholangiocarcinoma10.0MUC2, EIF4E, KRT20, CEACAM5
43bronchiolo-alveolar adenocarcinoma10.0MUC2, EIF4E, KRT20, CEACAM5
44adenosquamous carcinoma10.0MUC2, KRT20, CEACAM7, CEACAM5
45papillary carcinoma10.0CALB2, S100A4, MUC2, KRT20
46cervical adenocarcinoma10.0CALB2, KRT20, CEACAM7, CEACAM5
47glioblastoma multiforme10.0S100A4, TNFRSF6B, AREG, EIF4E
48carcinoid syndrome10.0VIP, CALB2, KRT20, CEACAM5
49cystadenocarcinoma10.0CEACAM5, MUC2, AREG
50inflammatory bowel disease10.0VIP, AREG, MUC2, SI

Graphical network of the top 20 diseases related to Colon Adenocarcinoma:



Diseases related to colon adenocarcinoma

Clinical Features for Colon Adenocarcinoma

Drugs & Therapeutics for Colon Adenocarcinoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Colon Adenocarcinoma

Drug clinical trials:

Search ClinicalTrials for Colon Adenocarcinoma

Search NIH Clinical Center for Colon Adenocarcinoma

Search CenterWatch for Colon Adenocarcinoma

Genetic Tests for Colon Adenocarcinoma

Anatomical Context for Colon Adenocarcinoma

Animal Models for Colon Adenocarcinoma or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Colon Adenocarcinoma

Sources:
51PubMed
See all sources

Articles related to Colon Adenocarcinoma:

(show top 50)    (show all 860)
idTitleAuthorsYear
1
Oncogenic osteomalacia due to FGF23-expressing colon adenocarcinoma. (23393166)
2013
2
Leptomeningeal metastasis from occult signet-ring cell colon adenocarcinoma presenting with isolated headache. (23477876)
2013
3
Cytotoxic and apoptotic effects of chalcone derivatives of 2-acetyl thiophene on human colon adenocarcinoma cells. (22987398)
2013
4
Human PXR-mediated induction of intestinal CYP3A4 attenuates 1I+,25-dihydroxyvitamin Da88 function in human colon adenocarcinoma LS180 cells. (22562045)
2012
5
Clinical significance of incidental colonic 18F-FDG uptake on PET/CT images in patients with gastric adenocarcinoma. (22752472)
2012
6
Extensively infiltrating colon adenocarcinoma similar to Crohn's disease: a case report. (22326249)
2012
7
Metastatic seeding of colon adenocarcinoma manifesting as synchronous breast and chest wall localization: report of a case. (21264761)
2011
8
Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adenocarcinoma cells without inducing apoptosis. (21965738)
2011
9
Colon mucinous adenocarcinoma in childhood: a case report with emphasis on image findings. (20369060)
2010
10
Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma. (19737943)
2009
11
Two-dimensional electrophoretic analysis of nuclear matrix proteins in human colon adenocarcinoma. (19274585)
2009
12
Isolation of Acremonium strictum from pleural fluid of a patient with colon adenocarcinoma. (18627474)
2009
13
The proapoptotic C16-ceramide-dependent pathway requires the death-promoting factor Btf in colon adenocarcinoma cells. (19705920)
2009
14
Matrix metalloproteinase-9 associated with heparan sulphate chains of GPI-anchored cell surface proteoglycans mediates motility of murine colon adenocarcinoma cells. (18216069)
2008
15
Heat shock protein 72 associated with CD44v6 in human colonic adenocarcinoma. (18387829)
2008
16
MicroRNA expression in colon adenocarcinoma. (18544721)
2008
17
Synergistic anti-tumor effect of recombinant chicken fibroblast growth factor receptor-1-mediated anti-angiogenesis and low-dose gemcitabine in a mouse colon adenocarcinoma model. (17552033)
2007
18
Laryngeal metastasis from sigmoid colon adenocarcinoma followed by peristomal recurrence. (16720454)
2006
19
Elevation of radiolabelled thymidine uptake in RIF-1 fibrosarcoma and HT29 colon adenocarcinoma cells after treatment with thymidylate synthase inhibitors. (16568206)
2006
20
5alpha,8alpha-Epidioxy-22E-ergosta-6,9(11),22-trien-3beta-ol from an edible mushroom suppresses growth of HL60 leukemia and HT29 colon adenocarcinoma cells. (16595913)
2006
21
Nitric oxide impairs the 17beta-estradiol-induced apoptosis in human colon adenocarcinoma cells. (16728582)
2006
22
Hypersialylation of beta1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility. (15930282)
2005
23
A Phase I trial of preoperative eniluracil plus 5-fluorouracil and radiation for locally advanced or unresectable adenocarcinoma of the rectum and colon. (14967434)
2004
24
Identification of genes responsive to intracellular zinc depletion in the human colon adenocarcinoma cell line HT-29. (14704293)
2004
25
Liver transplantation for metastatic colon adenocarcinoma: report of a case with 10 years of follow-up without recurrence. (12802483)
2003
26
Transcriptional regulation of human beta-galactoside alpha2,6-sialyltransferase (hST6Gal I) gene in colon adenocarcinoma cell line. (12878221)
2003
27
The role of galactose, lactose, and galactose valency in the biorecognition of N-(2-hydroxypropyl)methacrylamide copolymers by human colon adenocarcinoma cells. (12240936)
2002
28
Increased apoptosis in metastatic human colonic adenocarcinomas. (12170764)
2002
29
Poorly differentiated adenocarcinoma and mucinous carcinoma of the colon and rectum show higher rates of loss of heterozygosity and loss of E-cadherin expression due to methylation of promoter region. (12397640)
2002
30
Colocalization of BAX with BID and VDAC-1 in nimesulide-induced apoptosis of human colon adenocarcinoma COLO 205 cells. (12439336)
2002
31
Inhibition of proliferation of HT-29 colon adenocarcinoma cells by carboxylate NSAIDs and their acyl glucuronides. (11764005)
2001
32
Elevated expression of caveolin-1 in adenocarcinoma of the colon. (11345836)
2001
33
Calretinin and calretinin-22k increase resistance toward sodium butyrate-induced differentiation in CaCo-2 colon adenocarcinoma cells. (11461122)
2001
34
Increased expression of cFLIP(L) in colonic adenocarcinoma. (11329136)
2001
35
Sp1 and Sp3 activate p21 (WAF1/CIP1) gene transcription in the Caco-2 colon adenocarcinoma cell line. (11064455)
2000
36
Gastrocolic fistula due to adenocarcinoma of the colon: simulation of primary gastric leiomyosarcoma on CT. (10665346)
1999
37
Human mannose-binding lectin preferentially binds to human colon adenocarcinoma cell lines expressing high amount of Lewis A and Lewis B antigens. (10328552)
1999
38
Effects of sulindac, sulindac metabolites, and aspirin on the activity of detoxification enzymes in HT-29 human colon adenocarcinoma cells. (10660094)
1999
39
Reduced metastatic potential and c-myc overexpression of colon adenocarcinoma cells (Colon 26 line) transfected with nm23-R2/rat nucleoside diphosphate kinase alpha isoform. (9854145)
1998
40
Sulindac sulfide alters the expression of cyclin proteins in HT-29 colon adenocarcinoma cells. (9533768)
1998
41
Detection and quantitation of thymidylate synthase mRNA in human colon adenocarcinoma cell line resistant to 5-fluorouracil by competitive PCR. (9673356)
1998
42
Expression of Fas ligand in liver metastases of human colonic adenocarcinomas. (9177233)
1997
43
Characterization of a clonal human colon adenocarcinoma line intrinsically resistant to doxorubicin. (9218735)
1997
44
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in colonic adenomas-adenocarcinomas. (8918435)
1996
45
Active transport of glutathione S-conjugate in human colon adenocarcinoma cells. (8950221)
1996
46
Quinone-induced apoptosis in human colon adenocarcinoma cells via DT-diaphorase mediated bioactivation. (8653808)
1996
47
Potentiation of 5-fluorouracil-leucovorin activity by alpha2a-interferon in colon adenocarcinoma xenografts. (9815884)
1995
48
Anti-colony-stimulating factor-1 antibody staining in primary breast adenocarcinomas correlates with marked inflammatory cell infiltrates and prognosis. (8271294)
1994
49
Comparative tumor morphogenesis of two human colon adenocarcinoma cell clones xenografted in the immunosuppressed newborn rat. (7903648)
1993
50
Smoldering DIC associated with widespread colonic mucinous adenocarcinoma. (7400696)
1980

Genetic Variations for Colon Adenocarcinoma

Expression for genes affiliated with Colon Adenocarcinoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Colon Adenocarcinoma

Search GEO for disease gene expression data for Colon Adenocarcinoma.

Pathways for genes affiliated with Colon Adenocarcinoma

Compounds for genes affiliated with Colon Adenocarcinoma

Sources:
45Novoseek, 60Tocris Bioscience, 29IUPHAR, 11DrugBank, 24HMDB, 50PharmGKB
See all sources

Compounds related to Colon Adenocarcinoma according to GeneCards/GeneDecks:

(show all 33)
idCompoundScoreTop Affiliating Genes
1progesterone45 60 29 11 2415.9CALB2, S100A4, AREG, MUC2, EIF4E, KRT20
2tyrosine4511.9VIP, CALB2, S100A4, AREG, EIF4E, SI
3calcium45 50 11 2414.8VIP, CALB2, S100A4, AREG, MUC2, HPSE
4thymidine45 2412.8VIP, CALB2, AREG, TYMS, SI, LGALS4
5retinoic acid45 2412.8S100A4, AREG, MUC2, CDX1, EIF4E, LGALS4
6polysaccharide4511.7AREG, TYMS, HPSE, SI, LGALS4, FUT4
7vegf4511.6VIP, AREG, TYMS, HPSE, EIF4E, KRT20
8cysteine4511.6VIP, TYMS, MUC2, EIF4E, SI, LGALS4
9steroid4511.4LGALS4, ACSL4, EIF4E, S100A4, CALB2
10paraffin4511.4CEACAM5, KRT20, SI, MUC2, CALB2
11mucicarmine4511.3CALB2, KRT20, CEACAM7, CEACAM5
12glucose4511.3MUC2, HPSE, EIF4E, SI, LGALS4, CEACAM5
13b 7234511.3CALB2, KRT20, CEACAM7, CEACAM5
14hematoxylin4511.3CALB2, MUC2, KRT20, CEACAM5
15gefitinib45 50 1113.3AREG, TYMS, CEACAM7, CEACAM5
16carbohydrates4511.3MUC2, SI, FUT4, CEACAM5
175-aza-2deoxycytidine4511.2S100A4, MUC2, CDX1, HPSE
18estrogen4511.2CEACAM7, SI, CALB2
19butyrate4511.2CEACAM7, SI, CALB2
205fluorouracil4511.2TYMS, MUC2, CEACAM7, CEACAM5
21serine4511.2VIP, AREG, TYMS, MUC2, HPSE, EIF4E
22crcs4511.2MUC2, CDX1, CEACAM5
23testosterone45 60 11 2414.1VIP, CALB2, AREG, KRT20, LGALS4
24lactose45 1112.1FUT4, LGALS4, SI
25triiodothyronine4511.0SI, LGALS4, CEACAM7
262,2,5,5-TETRAMETHYL-3-(SULFANYLMETHYL)-2,5-DIHYDRO-1H-PYRROL-1-OL1111.0CEACAM5, EIF4E
27n-acetylglucosamine4511.0CEACAM5, FUT4, HPSE
285-fluorocytosine4510.9CEACAM5, TYMS
29actinomycin d4510.9CEACAM7, EIF4E, MUC2, AREG
30galactose4510.9FUT4, LGALS4, MUC2
315-deoxy-5-fluorouridine4510.9CEACAM5, TYMS
32mitomycin c4510.8CEACAM5, TYMS, AREG
33oligonucleotide4510.8S100A4, AREG, MUC2, HPSE, EIF4E

GO Terms for genes affiliated with Colon Adenocarcinoma

Products for genes affiliated with Colon Adenocarcinoma

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  • Proteins
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  • Antibodies

Sources for Colon Adenocarcinoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet