MCID: CLR019
MIFTS: 46

Color Blindness malady

Eye diseases category
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Summaries for Color Blindness

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Sources:
8Disease Ontology, 34MedlinePlus, 65Wikipedia, 33MalaCards
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MedlinePlus:34 Most of us see our world in color. we enjoy looking at a lush green lawn or a red rose in full bloom. if you have a color vision defect, you may see these colors differently than most people. there are three main kinds of color vision defects. red-green color vision defects are the most common. this type occurs in men more than in women. the other major types are blue-yellow color vision defects and a complete absence of color vision. most of the time, color blindness is genetic. there is no treatment, but most people adjust and the condition doesn't limit their activities.

MalaCards: Color Blindness, also known as colour vision deficiency, is related to blue cone monochromacy and blue color blindness. An important gene associated with Color Blindness is OPN1SW (opsin 1 (cone pigments), short-wave-sensitive), and among its related pathways are Potassium transporters inward current and Opsins. The compounds hypoxanthine and Cyclic GMP have been mentioned in the context of this disorder. Affiliated tissues include testes, eye and liver, and related mouse phenotype vision/eye.

Disease Ontology:8 A blindness that is characterized by the inability or decreased ability to see color, or perceive color differences, under normal lighting conditions.

Wikipedia:65 Color blindness, or color vision deficiency, is the inability or decreased ability to see color, or... more...

Aliases & Classifications for Color Blindness

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Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 34MedlinePlus, 62UMLS, 58SNOMED-CT, 35MeSH, 40NCIt, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

color blindness 8 10 45 34 62
colour vision deficiency 8
color blindness nos 8
colour blindness 8
blindness color 8


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Disease Ontology8 DOID:13399
MeSH35 D003117
NCIt40 C3891
ICD9CM27 368.5
ICD1025 H53.5

Related Diseases for Color Blindness

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Color Blindness:



Diseases related to color blindness

Symptoms for Color Blindness

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Drugs & Therapeutics for Color Blindness

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Color Blindness

Search NIH Clinical Center for Color Blindness

Genetic Tests for Color Blindness

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Anatomical Context for Color Blindness

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Sources:
33MalaCards
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MalaCards organs/tissues related to Color Blindness:

33
Testes, Eye, Liver, Retina, Prostate

Animal Models for Color Blindness or affiliated genes

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Sources:
37MGI
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MGI Mouse Phenotypes related to Color Blindness:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053919.1OPN1MW, OPA1, OPN1SW, CNGA3, CNGB3

Publications for Color Blindness

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Sources:
52PubMed
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Articles related to Color Blindness:

(show top 50)    (show all 180)
idTitleAuthorsYear
1
More on color blindness. (22036741)
2011
2
The incidence of color blindness among some school children of Pokhara, Western Nepal. (20677611)
2010
3
On the malleability of ideology: motivated construals of color blindness. (19309207)
2009
4
Gene therapy for color blindness. (20018970)
2009
5
Congenital color blindness in young Turkish men. (16019694)
2005
6
Statistical and molecular analyses of evolutionary significance of red-green color vision and color blindness in vertebrates. (15647522)
2005
7
Red laser pointers and color blindness. (10076196)
1999
8
Cortical color blindness is not "blindsight for color". (9787052)
1998
9
A two-and-a-half color rainbow. Color blindness in physicians. (7980102)
1994
10
Ethambutol-induced color-blindness in goldfish: a behavioral, electrophysiological and morphological study. (1798615)
1991
11
Bicuculline produces reversible red-green color blindness in goldfish, as revealed by monocular behavioral testing. (1663295)
1991
12
Spectral characteristics of early receptor potential in congenital red-green color blindness. (3488889)
1986
13
Testing for degrees of color blindness. (6604891)
1983
14
Color blindness linkage to bipolar manic-depressive illness. New evidence. (316316)
1979
15
A new type of mucolipidosis associated with hereditary thrombocytopathy and color blindness. (200061)
1977
16
X chromosome and color blindness. (304200)
1977
17
A dominant X-linked factor in manic-depressive illness: studies with color blindness. (1080856)
1975
18
Prevalence of color blindness. (4541344)
1973
19
Considerations in regard to a proposed association of alcoholism and color blindness. (4537695)
1972
20
Visual acuity and color blindness among Brazilian Cayapo Indians. (4537649)
1972
21
Relationship of color blindness to alcoholic liver damage. (5312721)
1970
22
Lack of association between color blindness and alcoholism. (5312326)
1970
23
Genetic studies of the Seneca Indians: haptoglobins, transferrins, G-6-PD deficiency, hemoglobinopathy, color blindness, morphological traits and dermatoglyphics. (5301686)
1968
24
Red/green color blindness in the Niger delta. (5298588)
1967
25
The genetics of alcoholism and color blindness. (5343138)
1967
26
Frequency of color blindness among East Kentish children. (5297641)
1966
27
TOTAL COLOR BLINDNESS AND ALBINISM. TWO CAUSES OF SUBNORMAL VISUAL ACUITY IN CHILDREN. (14256521)
1965
28
Human color vision and color blindness. (4956617)
1965
29
COLOR BLINDNESS AMONG INDIANS FROM SANTA CATARINA, BRAZIL. (14220463)
1964
30
Congenital total color blindness: a clincopathological report. (13711836)
1960
31
Color-blindness among the Chinese. (13537225)
1958
32
Graham's theory of color blindness. (13571371)
1958
33
Imbecility and color blindness. (13444323)
1957
34
The denial of color-blindness. (13478654)
1957
35
Color-blindness among the Chinese; a survey in Canton. (13141347)
1953
36
What do the color blind see; a report on monocular color blindness. (12985793)
1952
37
Sex-linked nystagmus associated with red-green color-blindness. (17948382)
1949
38
An experiment in pursuit of color-blindness. (18119756)
1949
39
Incidence of color-blindness among psychotic subjects. (18893198)
1948
40
Industrial use of the Ishihara tests for color blindness. (20288890)
1947
41
Report on the effect of training in color blindness. (20239993)
1947
42
Hysterical color blindness; caused by infantile sexual guilt. (20279116)
1946
43
VITAMIN A FOR COLOR-BLINDNESS. (17790871)
1942
44
THE INCIDENCE OF COLOR-BLINDNESS AMONG JEWISH MALES. (17740625)
1936
45
ON COLOR BLINDNESS. (17816900)
1898
46
Color-Blindness. (17748195)
1889
47
COLOR-BLINDNESS. (17771530)
1889
48
Color-Blindness. (17788453)
1888
49
TESTS FOR COLOR-BLINDNESS. (17775197)
1881
50
ON COLOR BLINDNESS. (17736206)
1880

Variations for Color Blindness

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Expression for genes affiliated with Color Blindness

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Color Blindness

Search GEO for disease gene expression data for Color Blindness.

Pathways for genes affiliated with Color Blindness

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Sources:
50PathCards, 12EMD Millipore, 55Reactome, 38NCBI BioSystems Database, 30KEGG, 53QIAGEN
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Compounds for genes affiliated with Color Blindness

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Sources:
45Novoseek, 24HMDB, 11DrugBank, 51PharmGKB
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Compounds related to Color Blindness according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1hypoxanthine45 24 1111.9G6PD, F9
2Cyclic GMP249.5PDE6H, CNGA3, CNGB3
3midazolam45 51 1111.1GABRA3, G6PD

GO Terms for genes affiliated with Color Blindness

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16Gene Ontology
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Cellular components related to Color Blindness according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1photoreceptor outer segment membraneGO:0426229.5OPN1LW, OPN1SW, CNGA3
2integral component of plasma membraneGO:0058878.1OPN1LW, OPN1SW, GABRA3, CNGA3, CNGB3, XG

Biological processes related to Color Blindness according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1protein-chromophore linkageGO:01829810.1OPN1SW, OPN1LW
2regulation of membrane potentialGO:0423919.9CNGA3, CNGB3
3potassium ion transmembrane transportGO:0718059.8CNGB3, CNGA3
4retinoid metabolic processGO:0015239.7OPN1LW, OPN1SW
5phototransduction, visible lightGO:0076039.5OPN1LW, OPN1SW, CNGA3, CNGB3
6transportGO:0068109.1GABRA3, CNGA3, CNGB3
7visual perceptionGO:0076018.9OPN1LW, CNGB3, CNGA3, PDE6H, OPN1SW, OPA1

Molecular functions related to Color Blindness according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1photoreceptor activityGO:0098819.9OPN1SW, OPN1LW
2intracellular cGMP activated cation channel activityGO:0052239.9CNGA3, CNGB3
3voltage-gated potassium channel activityGO:0052499.9CNGA3, CNGB3
4cGMP bindingGO:0305539.6PDE6H, CNGA3, CNGB3
5intracellular cAMP activated cation channel activityGO:0052229.6CNGB3, CNGA3

Products for genes affiliated with Color Blindness

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Sources for Color Blindness

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet