MCID: CLR083
MIFTS: 24

Colorectal Cancer 8 malady

Categories: Cancer diseases, Genetic diseases, Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Colorectal Cancer 8

Aliases & Descriptions for Colorectal Cancer 8:

Name: Colorectal Cancer 8 54 29
Colorectal Cancer, Susceptibility to, 8 13

Classifications:



External Ids:

OMIM 54 612589

Summaries for Colorectal Cancer 8

MalaCards based summary : Colorectal Cancer 8, also known as colorectal cancer, susceptibility to, 8, is related to colorectal cancer, hereditary nonpolyposis, type 8 and epcam-related lynch syndrome. An important gene associated with Colorectal Cancer 8 is CRCS8 (Colorectal Cancer, Susceptibility To, 8). The drugs Iron and Fluorouracil have been mentioned in the context of this disorder.

Description from OMIM: 612589

Related Diseases for Colorectal Cancer 8

Symptoms & Phenotypes for Colorectal Cancer 8

Clinical features from OMIM:

612589

Drugs & Therapeutics for Colorectal Cancer 8

Drugs for Colorectal Cancer 8 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 434)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Iron Approved Phase 4 7439-89-6 23925
2
Fluorouracil Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-21-8 3385
3
Oxaliplatin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 61825-94-3 5310940 9887054 6857599, 9887054 43805
4
Capecitabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 154361-50-9 60953
5
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 772 46507594
6
Cetuximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 205923-56-4 56842117 2333
7
Irinotecan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 97682-44-5, 100286-90-6 60838
8
Benzocaine Approved Phase 4 1994-09-7, 94-09-7 2337
9
Bisacodyl Approved Phase 4 603-50-9
10
Cefuroxime Approved Phase 4 55268-75-2 5361202 5479529
11
Metronidazole Approved Phase 4,Phase 3,Phase 1 443-48-1 4173
12
Sulfamethoxazole Approved Phase 4 723-46-6 5329
13
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
14
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 58-05-9 54575, 6560146 143
15
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 59-30-3 6037
16
Menadione Approved, Nutraceutical Phase 4,Phase 2 58-27-5 4055
17
Phytonadione Approved, Nutraceutical Phase 4,Phase 2 84-80-0 4812 5284607
18 tannic acid Approved, Nutraceutical Phase 4
19 Ferrous fumarate Phase 4
20 Micronutrients Phase 4,Phase 3,Phase 2,Phase 1
21 Trace Elements Phase 4,Phase 3,Phase 2,Phase 1
22 Antimetabolites Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
23 Antimetabolites, Antineoplastic Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
24 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
25 calcium heparin Phase 4,Phase 3,Phase 2
26 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
27 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1,Phase 2
28 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1
29 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
30 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
31 Antimalarials Phase 4,Phase 2
32 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Phase 1
33 Antiprotozoal Agents Phase 4,Phase 3,Phase 2,Phase 1
34 Vitamin B Complex Phase 4,Phase 3,Phase 2,Phase 1
35 Antibodies Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
36 Antibodies, Monoclonal Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
37 Immunoglobulins Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
38 Vitamin K 1 Phase 4,Phase 2
39 Vitamins Phase 4,Phase 3,Phase 2,Phase 1
40 Adjuvants, Immunologic Phase 4,Phase 3,Phase 2,Phase 1
41 interferons Phase 4,Phase 3,Phase 1,Phase 2
42 Cathartics Phase 4,Phase 2,Phase 1
43 Laxatives Phase 4,Phase 2,Phase 1
44 cefuroxime axetil Phase 4
45 Cytochrome P-450 Enzyme Inhibitors Phase 4
46 Folic Acid Antagonists Phase 4,Phase 2,Phase 1
47 Renal Agents Phase 4
48 Trimethoprim, Sulfamethoxazole Drug Combination Phase 4
49 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
50
Serotonin Phase 4,Phase 3,Phase 2 50-67-9 5202

Interventional clinical trials:

(show top 50) (show all 645)
id Name Status NCT ID Phase
1 Trial Comparing Ferric(III)Carboxymaltose Infusion With Oral Iron Suppletion as Treatment of Anaemia Unknown status NCT02243735 Phase 4
2 Oxaliplatine Based Adjuvant Chemotherapy for Stage II/III Colorectal Cancer: 8 Cycles Versus 12 Cycles Completed NCT00868816 Phase 4
3 Nutrition for Colorectal Cancer Patients and Neutrophil Functions Completed NCT01831310 Phase 4
4 A Study of Capecitabine (Xeloda) in the Adjuvant Treatment of Participants With Resected Colon Cancer Completed NCT02581423 Phase 4
5 Safety of Orectalip® (Oxaliplatin) as Adjuvant Treatment for High-risk Stage-Ⅱ Colorectal Cancer Completed NCT02284529 Phase 4
6 Pharmacology-driven Dosing of Fluoropyrimidines in Cancer Patients Completed NCT01641458 Phase 4
7 Improvement of Fluid Balance in Patients Undergoing Surgery of the Colon and Rectum Completed NCT01175317 Phase 4
8 Efficacy of 2-Liter Mixed Preparation With Bisacodyl Plus Polyethylene Glycol and 4-Liter Polyethylene Glycol for Colon Cleansing in Patients With Prior History of Colorectal Resection Completed NCT01887158 Phase 4
9 Orally Administered Trimethoprim-sulfamethoxazole and Metronidazole as Prophylaxis of Infection Following Elective Colorectal Surgery Completed NCT00613769 Phase 4
10 Phase IV Panitumumab Study in Indian Subjects With Metastatic Colorectal Cancer Recruiting NCT02301962 Phase 4
11 Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery Recruiting NCT02056405 Phase 4
12 FOLFIRI in Combination With Cetuximab in the First-line Treatment of Metastatic Colorectal Cancer Including a Regular Dermal Prophylaxis to Prevent Acneiforme Follicular Exanthema Active, not recruiting NCT01315990 Phase 4
13 Anal Dysplasia Study of Men Who Have Sex With Men Living With HIV Withdrawn NCT01663558 Phase 4
14 FOLFIRI or mFOLFOX6 in Adjuvant Chemotherapy in Advanced Colorectal Cancer Unknown status NCT01566942 Phase 3
15 Trial of FOLF(HA)Iri Versus FOLFIRI in mCRC Unknown status NCT01290783 Phase 3
16 Comparison of Laparoscopic Colectomy Versus Open Colectomy for Colorectal Cancer: … A Prospective Randomized Trial Unknown status NCT00155727 Phase 3
17 Trial of Preoperative Hepatic and Regional Arterial Chemotherapy (PHRAC) to Prevent Postoperative Liver Metastasis of Colorectal Cancer Unknown status NCT00643877 Phase 3
18 ONE WEEK VERSUS FOUR WEEK HEPARIN PROPHYLAXIS AFTER LAPAROSCOPIC SURGERY FOR COLORECTAL CANCER. Unknown status NCT01589146 Phase 3
19 Fluorouracil and Irinotecan With or Without Leucovorin Compared With Observation in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer Unknown status NCT00091312 Phase 3
20 Preoperative Radiotherapy and Local Excision in Rectal Cancer Unknown status NCT00738790 Phase 3
21 Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer Unknown status NCT01167725 Phase 3
22 Transrectal Vacuum Assisted Drainage: A New Method of Treating Anastomotic Leakage After Rectal Resection Unknown status NCT00773981 Phase 3
23 5-FU, Folinic Acid and Irinotecan (FOLFIRI) Plus Cetuximab Versus FOLFIRI Plus Bevacizumab in First Line Treatment Colorectal Cancer (CRC) Unknown status NCT00433927 Phase 3
24 Biological Therapy With Combination Chemotherapy in Patients With Colorectal Cancer Unknown status NCT00003063 Phase 3
25 The Randomised Study of Preoperative Radiotherapy With Consolidating Chemotherapy for Unresectable Rectal Cancer Unknown status NCT00833131 Phase 3
26 Preoperative Downstaging of Extraperitoneal T3 Rectal Cancer: XELOXRT Versus XELACRT. A Multicenter, Phase III Study Unknown status NCT01653301 Phase 3
27 A Trial of High Intensity Versus Low Intensity Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Unknown status NCT01064999 Phase 2, Phase 3
28 Trial Of Irinotecan In Combination With Three Methods Of Administration Of Fluoropyrimidine. Completed NCT00101686 Phase 3
29 XENOX – Evaluation of the Efficacy of Xaliproden in Reducing the Neurotoxicity of the Oxaliplatin + 5-FU/LV Chemotherapy Completed NCT00272051 Phase 3
30 Cetuximab Combined With Irinotecan in First-line Therapy for Metastatic Colorectal Cancer (CRYSTAL) Completed NCT00154102 Phase 3
31 Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy With 5-Fluorouracil and Oxaliplatin Versus 5-Fluorouracil Alone in Rectal Cancer Completed NCT00349076 Phase 3
32 Aspirin/Folate Prevention of Large Bowel Polyps Completed NCT00272324 Phase 2, Phase 3
33 Combination Chemotherapy in Treating Patients With Colorectal Cancer Completed NCT00006103 Phase 3
34 Cetuximab, Capecitabine, Oxaliplatin and Bevacizumab in Advanced Colorectal Cancer Completed NCT00208546 Phase 3
35 Study of Cetuximab, Oxaliplatin, 5-FU/LV Versus Oxaliplatin, 5-FU/LV in Patients With Previously Treated Metastatic, EGFR-Positive Colorectal Cancer Completed NCT00061815 Phase 3
36 A Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon Cancer Completed NCT00069121 Phase 3
37 Chemotherapy and Radiation Therapy Before Surgery Followed by Capecitabine With or Without Oxaliplatin in Treating Patients With Locally Advanced Rectal Cancer Completed NCT00766155 Phase 3
38 ABCSG 8 - Adjuvant Treatment in Patients With Hormone Receptor-positive Breast Cancer With Good to Moderate Differentiation. Completed NCT00291759 Phase 3
39 A Study of Xeloda (Capecitabine) in Patients With Metastatic Colorectal Cancer Completed NCT00069108 Phase 3
40 FLOX in Combination With Cetuximab in First-line Treatment of Colorectal Cancer Completed NCT00145314 Phase 3
41 S9415 Chemotherapy in Patients With Stage II or III Colon Cancer That Has Been Surgically Removed Completed NCT00002593 Phase 3
42 Radiation Therapy With or Without Chemotherapy Before Surgery in Treating Patients With Stage II or Stage III Rectal Cancer Completed NCT00296608 Phase 3
43 The Safety and Efficacy of Methylene Blue MMX® Modified Release Tablets Administered to Subjects Undergoing Screening or Surveillance Colonoscopy Completed NCT01694966 Phase 3
44 Combination Chemotherapy With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for High Risk Stage II or Stage III Colon Cancer Completed NCT00112918 Phase 3
45 Combination Chemotherapy With or Without Cetuximab in Treating Patients With Stage III Colon Cancer That Was Completely Removed By Surgery Completed NCT00265811 Phase 3
46 A Study of Xeloda (Capecitabine) Compared With 5-Fluorouracil in Combination With Low-Dose Leucovorin in Patients Who Have Undergone Surgery for Colon Cancer Completed NCT00009737 Phase 3
47 Tegafur-Uracil and Leucovorin or S-1 in Treating Patients With Stage III Colon Cancer That Has Been Completely Removed by Surgery Completed NCT00660894 Phase 3
48 A Trial Comparing Adjuvant Oral UFT/LV to 5-FU/l-LV in Stage III Colorectal Cancer (JCOG-0205-MF) Completed NCT00190515 Phase 3
49 Study Evaluating the Efficacy and Safety of Intranasal Administration of 100, 200, and 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi Directional Device in Subjects With Bilateral Nasal Polyposis Followed by an 8-Week Open-Label Exten Completed NCT01622569 Phase 3
50 A Study in Second Line Metastatic Colorectal Cancer Completed NCT01183780 Phase 3

Search NIH Clinical Center for Colorectal Cancer 8

Genetic Tests for Colorectal Cancer 8

Genetic tests related to Colorectal Cancer 8:

id Genetic test Affiliating Genes
1 Colorectal Cancer 8 29

Anatomical Context for Colorectal Cancer 8

Publications for Colorectal Cancer 8

Variations for Colorectal Cancer 8

Expression for Colorectal Cancer 8

Search GEO for disease gene expression data for Colorectal Cancer 8.

Pathways for Colorectal Cancer 8

GO Terms for Colorectal Cancer 8

Sources for Colorectal Cancer 8

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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