|1|Germline and somatic polymerase I/ and I' mutations define a new class of hypermutated colorectal and endometrial cancers. (23447401)
Briggs S.... Tomlinson I.
|2|Somatic mutations, allele loss, and DNA methylation of the Cub and Sushi Multiple Domains 1 (CSMD1) gene reveals association with early age of diagnosis in colorectal cancer patients. (23505554)
Shull A.Y.... Buckhaults P.J.
|3|Postmenopausal hormone therapy and colorectal cancer risk in relation to somatic KRAS mutation status among older women. (22337533)
Limburg P.J.... Cerhan J.R.
|4|A meta-analysis of the prevalence of somatic mutations in the hMLH1 and hMSH2 genes in colorectal cancer. (21988782)
Zhang R.... Li C.X.
|5|Somatic mutation of a tumor suppressor gene BAP1 is rare in breast, prostate, gastric and colorectal cancers. (22958294)
Je E.M.... Yoo N.J.
|6|Somatic MED12 mutations in uterine leiomyosarcoma and colorectal cancer. (23132392)
KAompjAorvi K.... Vahteristo P.
|7|Somatic mutations of caspase-2 gene in gastric and colorectal cancers. (21940110)
Kim M.S.... Lee S.H.
|8|BRAF p.Val600Glu (V600E) somatic mutation is mainly associated with MSS phenotype in metastatic colorectal cancer. (21289333)
Qiu J.... Olschwang S.
|9|Somatic mutations and germline sequence variants in patients with familial colorectal cancer. (21351276)
Gylfe A.E.... Aaltonen L.A.
|10|Somatic frameshift mutations of bone morphogenic protein receptor 2 gene in gastric and colorectal cancers with microsatellite instability. (20955454)
Park S.W.... Lee S.H.
|11|Somatic hypermethylation of MSH2 is a frequent event in Lynch Syndrome colorectal cancers. (20388775)
Nagasaka T.... Goel A.
|12|Somatic mutation of EXO1 gene in gastric and colorectal cancers with microsatellite instability. (20429728)
Kim Y.R.... Lee S.H.
|13|Smoking, gender, and ethnicity predict somatic BRAF mutations in colorectal cancer. (20200438)
Rozek L.S.... Gruber S.B.
|14|Somatic mutations and losses of expression of microRNA regulation-related genes AGO2 and TNRC6A in gastric and colorectal cancers. (20198652)
Kim M.S.... Lee S.H.
|15|Prognostic significance of interaction between somatic APC mutations and 5-fluorouracil adjuvant chemotherapy in Taiwanese colorectal cancer subjects. (19307944)
Chen S.P.... Harn H.J.
|16|Somatic APC inactivation mechanisms in sporadic colorectal cancer cases in Hungary. (18369740)
KA!mory E.... Csuka O.
|17|Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype. (18628431)
English D.R.... Giles G.G.
|18|Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer. (18541649)
Ito Y.... Murrell A.
|19|Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD). (18186519)
Bentivegna S.... Seymour A.B.
|20|Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. (18804418)
Linardou H.... Murray S.
|21|May the APC gene somatic mutations in tumor tissues influence the clinical features of Chinese sporadic colorectal cancers? (17653897)
Liu X.... Wang Y.
|22|MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer. (17621591)
Ogino S.... Fuchs C.S.
|23|Somatic mutation of MutYH in Tunisian patients with sporadic colorectal cancer. (18022921)
Bougatef K.... Ben Ammar Elgaaied A.
|24|Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer. (17453358)
Loughrey M.B.... Dobrovic A.
|25|Novel germline and somatic mutations of the MSH2 gene in hereditary non-polyposis colorectal cancer. (17250671)
Ding D.C.... Chu T.Y.
|26|Low somatic K-ras mutation frequency in colorectal cancer diagnosed under the age of 45 years. (16765042)
Alsop K.... Southey M.C.
|27|Somatic BRAF-V600E mutations in familial colorectal cancer. (17119056)
Vandrovcova J.... Lindblom A.
|28|Analysis of somatic molecular changes, clinicopathological features, family history, and germline mutations in colorectal cancer families: evidence for efficient diagnosis of HNPCC and for the existence of distinct groups of non-HNPCC families. (15788729)
Johnson V.... Tomlinson I.P.
|29|Chromosome 7q31 allelic imbalance and somatic mutations of RAY1/ST7 gene in colorectal cancer. (14670621)
Haddad R.... Gallinger S.
|30|Multiple epithelial and nonepithelial tumors in hereditary nonpolyposis colorectal cancer: characterization of germline and somatic mutations of the MSH2 gene and heterogeneity of replication error phenotypes. (15350299)
Huang R.L.... Chu T.Y.
|31|Somatic mutations of APC gene in carcinomas from hereditary non-polyposis colorectal cancer patients. (15040027)
Huang J.... Zhang S.Z.
|32|Novel germline hMSH2 genomic deletion and somatic hMSH2 mutations in a hereditary nonpolyposis colorectal cancer family. (15063132)
Miyaki M.... Mori T.
|33|Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers. (12707038)
Halford S.E.... Tomlinson I.P.
|34|hMLH1 and hMSH2 somatic inactivation mechanisms in sporadic colorectal cancer patients. (14688830)
KA!mory E.... Csuka O.
|35|Germline, somatic and epigenetic events underlying mismatch repair deficiency in colorectal and HNPCC-related cancers. (12386821)
Yuen S.T.... Leung S.Y.
|36|Involvement of hMSH6 in the development of hereditary and sporadic colorectal cancer revealed by immunostaining is based on germline mutations, but rarely on somatic inactivation. (11807791)
Plaschke J.... Schackert H.K.
|37|Germline and somatic mutation analyses in the DNA mismatch repair gene MLH3: evidence for somatic mutation in colorectal cancers. (11317354)
Lipkin S.M.... Collins F.S.
|38|Somatic alterations of the DPC4 and Madr2 genes in colorectal cancers and relationship to metastasis. (11172591)
Ohtaki N.... Urano T.
|39|Germline and somatic mutation analysis of MLH3 in MSI-positive colorectal cancer. (10934138)
Loukola A.... Aaltonen L.A.
|40|Absence of somatic alterations of the EB1 gene adenomatous polyposis coli-associated protein in human sporadic colorectal cancers. (9823979)
JaA^s P.... Bressac-de Paillerets B.
|41|Somatic alterations of the SMAD-2 gene in human colorectal cancers. (9820171)
Takagi Y.... Saji S.
|42|Somatic frameshift mutations in DNA mismatch repair and proapoptosis genes in hereditary nonpolyposis colorectal cancer. (9500462)
Yamamoto H.... Perucho M.
|43|Somatic mutations, acetylator status, and prognosis in colorectal cancer. (9659162)
Hardingham J.E.... Roberts-Thomson I.C.
|44|Hereditary nonpolyposis colorectal cancer: causative role of a germline missense mutation in the hMLH1 gene confirmed by the independent occurrence of the same somatic mutation in tumour tissue. (9272156)
Wang Y.... Propping P.
|45|Frequent somatic mutations of hMSH3 with reference to microsatellite instability in hereditary nonpolyposis colorectal cancers. (9240418)
Akiyama Y.... Yuasa Y.
|46|Somatic alterations of the DPC4 gene in human colorectal cancers in vivo. (8898652)
Takagi Y.... Saji S.
|47|Loss or somatic mutations of hMSH2 occur in hereditary nonpolyposis colorectal cancers with hMSH2 germline mutations. (8613431)
Lu S.L.... Yuasa Y.