MCID: CMB003
MIFTS: 17

Combined T Cell and B Cell Immunodeficiency malady

Immune diseases category

Summaries for Combined T Cell and B Cell Immunodeficiency

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Disease Ontology:9 A primary immunodeficiency disease that involves multiple components of the immune system, including both humoral immunity and cell-mediated immunity.

MalaCards based summary: Combined T Cell and B Cell Immunodeficiency, also known as congenital combined immunodeficiency, is related to adenosine deaminase deficiency and gamma chain deficiency. Affiliated tissues include t cells and b cells.

Aliases & Classifications for Combined T Cell and B Cell Immunodeficiency

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Combined T Cell and B Cell Immunodeficiency, Aliases & Descriptions:

Name: Combined T Cell and B Cell Immunodeficiency 9
Congenital Combined Immunodeficiency 9 60
X-Linked Combined Immunodeficiency Diseases 60
 
X-Linked Combined Immunodeficiency 9
Combined Immunodeficiency 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Immune diseases


External Ids:

Disease Ontology9 DOID:628
NCIt38 C27871
SNOMED-CT55 191003005
ICD9CM27 279.2

Related Diseases for Combined T Cell and B Cell Immunodeficiency

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Diseases related to Combined T Cell and B Cell Immunodeficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 220)
idRelated DiseaseScoreTop Affiliating Genes
1adenosine deaminase deficiency10.9
2gamma chain deficiency10.8
3hematopoietic stem cell transplantation10.6
4leukemia10.6
5achondroplasia and severe combined immunodeficiency10.6
6obesity10.5
7severe combined immunodeficiency, athabascan type10.5
8zap70-related severe combined immunodeficiency10.5
9severe combined immunodeficiency due to ikk2 deficiency10.4
10severe immunodeficiency, autosomal recessive, t-cell negative, b-cell negative, nk cell-positive10.4
11prostatitis10.4
12combined immunodeficiency, x-linked, moderate10.4
13lymphopenia10.4
14thyroiditis10.4
15zap-70 deficiency10.4
16omenn syndrome10.4
17immunodeficiency due to purine nucleoside phosphorylase deficiency10.4
18severe combined immunodeficiency10.4
19cd40 ligand deficiency10.4
20cd40 deficiency10.4
21dna ligase iv deficiency10.4
22reticular dysgenesis10.3
23lung cancer10.3
24severe combined immunodeficiency, t cell-negative, b-cell/natural killer-cell positive10.3
25severe combined immunodeficiency, b cell-negative10.3
26severe combined immunodeficiency, x-linked10.3
27severe combined immunodeficiency due to ada deficiency10.3
28intestinal atresia10.3
29severe combined immunodeficiency, atypical10.3
30combined immunodeficiency with skin granulomas10.3
31severe combined immunodeficiency due to lck deficiency10.3
32combined immunodeficiency due to dock8 deficiency10.3
33severe combined immunodeficiency due to coro1a deficiency10.3
34combined immunodeficiency t+ b+ due to partial rag1 deficiency10.3
35combined immunodeficiency due to malt1 deficiency10.3
36severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation10.3
37hepatitis10.3
38myeloma10.3
39combined immunodeficiency due to crac channel dysfunction10.3
40combined immunodeficiency due to cd3gamma deficiency10.3
41t-b+ severe combined immunodeficiency due to il-7ralpha deficiency10.3
42t-b+ severe combined immunodeficiency due to cd3delta/cd3epsilon/cd3zeta10.3
43t-b+ severe combined immunodeficiency due to cd45 deficiency10.3
44severe combined immunodeficiency due to complete rag1/2 deficiency10.3
45combined immunodeficiency due to orai1 deficiency10.3
46severe combined immunodeficiency due to dna-pkcs deficiency10.3
47combined immunodeficiency due to stim1 deficiency10.3
48combined immunodeficiency due to stk4 deficiency10.3
49severe combined immunodeficiency due to card11 deficiency10.3
50t-b+ severe combined immunodeficiency due to jak3 deficiency10.3

Graphical network of the top 20 diseases related to Combined T Cell and B Cell Immunodeficiency:



Diseases related to combined t cell and b cell immunodeficiency

Symptoms for Combined T Cell and B Cell Immunodeficiency

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Drugs & Therapeutics for Combined T Cell and B Cell Immunodeficiency

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Drug clinical trials:

Search ClinicalTrials for Combined T Cell and B Cell Immunodeficiency

Search NIH Clinical Center for Combined T Cell and B Cell Immunodeficiency

Genetic Tests for Combined T Cell and B Cell Immunodeficiency

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Anatomical Context for Combined T Cell and B Cell Immunodeficiency

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MalaCards organs/tissues related to Combined T Cell and B Cell Immunodeficiency:

31
T cells, B cells

Animal Models for Combined T Cell and B Cell Immunodeficiency or affiliated genes

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Publications for Combined T Cell and B Cell Immunodeficiency

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Variations for Combined T Cell and B Cell Immunodeficiency

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Expression for genes affiliated with Combined T Cell and B Cell Immunodeficiency

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Search GEO for disease gene expression data for Combined T Cell and B Cell Immunodeficiency.

Pathways for genes affiliated with Combined T Cell and B Cell Immunodeficiency

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Compounds for genes affiliated with Combined T Cell and B Cell Immunodeficiency

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GO Terms for genes affiliated with Combined T Cell and B Cell Immunodeficiency

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Products for genes affiliated with Combined T Cell and B Cell Immunodeficiency

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Combined T Cell and B Cell Immunodeficiency

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet