Common Cold

Categories: Respiratory diseases, Infectious diseases

Aliases & Classifications for Common Cold

MalaCards integrated aliases for Common Cold:

Name: Common Cold 12 52 41 3 42 14 69
Acute Nasopharyngitis [common Cold] 12
Acute Viral Rhinopharyngitis 12
Nasopharyngitis - Acute 12
Nasopharyngitis, Acute 12
Acute Nasopharyngitis 12
Rhino-Sinusitis 12
Acute Rhinitis 12
Acute Coryza 12


External Ids:

Disease Ontology 12 DOID:10459
ICD10 33 J00
ICD9CM 35 460
MeSH 42 D003139
UMLS 69 C0009443

Summaries for Common Cold

MedlinePlus : 41 sneezing, sore throat, a stuffy nose, coughing - everyone knows the symptoms of the common cold. it is probably the most common illness. in the course of a year, people in the united states suffer 1 billion colds. you can get a cold by touching your eyes or nose after you touch surfaces with cold germs on them. you can also inhale the germs. symptoms usually begin 2 or 3 days after infection and last 2 to 14 days. washing your hands and staying away from people with colds will help you avoid colds. there is no cure for the common cold. for relief, try getting plenty of rest drinking fluids gargling with warm salt water using cough drops or throat sprays taking over-the-counter pain or cold medicines however, do not give aspirin to children. and do not give cough medicine to children under four. nih: national institute of allergy and infectious diseases

MalaCards based summary : Common Cold, also known as acute nasopharyngitis [common cold], is related to myocardial infarction and asthma, and has symptoms including coughing, fever and pruritus. An important gene associated with Common Cold is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Montelukast and Ethanol have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and bone, and related phenotypes are hematopoietic system and homeostasis/metabolism

CDC : 3 Common colds are the main reason that children miss school and adults miss work. Each year in the United States, there are millions of cases of the common cold. Adults have an average of 2-3 colds per year, and children have even more.

Disease Ontology : 12 An upper respiratory tract disease which involves inflammation of the mucous membranes of the nose, throat, eyes, and eustachian tubes with watery then purulent discharge. This is an acute contagious disease caused by rhinoviruses, human parainfluenza viruses, human respiratory syncytial virus, influenza viruses, adenoviruses, enteroviruses, or metapneumovirus.

Wikipedia : 72 The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory... more...

Related Diseases for Common Cold

Diseases related to Common Cold via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 170)
id Related Disease Score Top Affiliating Genes
1 myocardial infarction 28.9 ALB CCL5 ICAM1 LDLR SELP
2 asthma 24.8 CCL11 CCL5 CXCL8 ICAM1 IL13 IL1R1
3 nasopharyngitis 11.3
4 rhinitis 11.1
5 influenza 11.0
6 otosalpingitis 10.9
7 hidradenitis suppurativa 10.6 CCL11 CCL5 CXCL8
8 viral infectious disease 10.6
9 pertussis 10.6
10 congenital diaphragmatic hernia 10.6 CXCL8 ICAM1
11 cytomegalovirus retinitis 10.6 CXCL8 ICAM1
12 penis agenesis 10.6 CCL11 IL5
13 myopathy 10.5 CXCL8 IFNA2 IL1R1
14 carcinoma arising in nasal papillomatosis 10.5 ALB CCL5 CXCL8
15 vulvar disease 10.5 CCL5 RNASE3 SELP
16 late yaws 10.5 ALB CCL5 TLR9
17 dysphagia 10.5 CCL5 CXCL8 ICAM1
18 lymph node palisaded myofibroblastoma 10.4 CCL11 CXCL8
19 papillary follicular thyroid adenocarcinoma 10.4 IL5 RNASE3
20 alopecia 10.4 ALB CXCL8 ICAM1
21 noninfectious dermatoses of eyelid 10.4 ALB IFNA2 TLR9
22 intra-abdominal lymph node mast cell malignancy 10.4 CXCL8 ICAM1 SELP
23 common peroneal nerve lesion 10.4 CXCL8 IL5
24 angiokeratoma 10.4 ICAM1 SELP TLR9
25 scabies 10.4 ALB CXCL8 ICAM1
26 sheehan syndrome 10.4 ALB CXCL8 TLR9
27 diabetic encephalopathy 10.4 CXCL8 ICAM1 SELP
28 capillary leak syndrome 10.3 ALB CXCL8
29 cytoplasmic body myopathy 10.3 IL13 IL5
30 endometrial clear cell adenocarcinoma 10.3 ALB CXCL8 TLR9
31 psychotic disorder 10.3 CCL11 CXCL8 IL4
32 retinal vascular disease 10.3 CCL11 CXCL8 IL4
33 chronic endophthalmitis 10.3 ALB CCL5 CXCL8 ICAM1
34 gonococcal endophthalmia 10.3 CCL5 IL5 TLR9
35 signet ring cell adenocarcinoma 10.3 IL1R1 IL5 RNASE3
36 anterior dislocation of lens 10.3 CCL11 IL4 RNASE3
37 skin disease 10.3 CXCL8 IL5 RNASE3
38 peripheral artery disease 10.2 ALB ICAM1 LDLR SELP
39 tuberculum sellae meningioma 10.2 ALB CCL11 CXCL8 TLR9
40 pulmonary embolism 10.2 ALB CXCL8 TLR9
41 hypercementosis 10.2 CCL5 IL13 IL5
42 basidiobolomycosis 10.2 CXCL8 IL4
43 vascular dementia 10.2 CCL5 IL4 TLR9
44 cholesteatoma of middle ear 10.2 CCL11 IL13 IL5
45 lymphocytic gastritis 10.2 ALB CCL11 IL5 RNASE3
46 aortic arch interruption 10.2 IL13 IL5
47 bartholin's duct cyst 10.2 CCL11 IL5 RNASE3
48 exudative vitreoretinopathy 2, x-linked 10.2 ALB IL13 IL5
49 mikulicz disease 10.2 ALB IL4 TLR9
50 ileitis 10.2 ICAM1 IL4

Comorbidity relations with Common Cold via Phenotypic Disease Network (PDN):

Bronchitis Heart Disease

Graphical network of the top 20 diseases related to Common Cold:

Diseases related to Common Cold

Symptoms & Phenotypes for Common Cold

UMLS symptoms related to Common Cold:

coughing, fever, pruritus, snoring, sore throat, vertigo/dizziness, equilibration disorder, rhinorrhea, catarrh

MGI Mouse Phenotypes related to Common Cold:

id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.1 CCL11 CCL5 ICAM1 IL13 IL1R1 IL33
2 homeostasis/metabolism MP:0005376 10.03 ALB ICAM1 IL13 IL1R1 IL33 IL4
3 digestive/alimentary MP:0005381 10.02 IL13 IL33 IL4 IL5 LDLR TLR9
4 immune system MP:0005387 9.93 TLR9 TSLP CCL11 CCL5 ICAM1 IL13
5 integument MP:0010771 9.56 ICAM1 IL13 IL1R1 IL33 IL4 LDLR
6 respiratory system MP:0005388 9.23 CCL11 IL13 IL1R1 IL33 IL4 IL5

Drugs & Therapeutics for Common Cold

Drugs for Common Cold (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 228)
id Name Status Phase Clinical Trials Cas Number PubChem Id
Montelukast Approved Phase 4,Phase 3 158966-92-8 5281040
Ethanol Approved Phase 4 64-17-5 702
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
Acetaminophen Approved Phase 4,Phase 3,Phase 2 103-90-2 1983
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 299-42-3 9294
Guaifenesin Approved, Vet_approved Phase 4,Phase 3,Phase 2 93-14-1 3516
Histamine Approved, Investigational Phase 4,Phase 3,Phase 1 75614-87-8, 51-45-6 774
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 90-82-4 7028
Oxymetazoline Approved Phase 4,Phase 3,Phase 1 1491-59-4 4636
Phenylephrine Approved Phase 4,Phase 3,Phase 1 59-42-7 6041
Aspirin Approved, Vet_approved Phase 4,Phase 3 50-78-2 2244
Ipratropium Approved Phase 4 22254-24-6, 60205-81-4 43232
Dextromethorphan Approved Phase 4 125-71-3 5360696 5362449
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3 55-56-1 9552079 2713
Azelastine Approved Phase 4,Phase 3 58581-89-8 2267
Capsaicin Approved Phase 4,Phase 2 404-86-4 1548943
Caffeine Approved, Nutraceutical Phase 4,Phase 3 58-08-2 2519
Vitamin C Approved, Nutraceutical Phase 4,Phase 3 50-81-7 5785 54670067
Ginseng Approved, Nutraceutical Phase 4 50647-08-0
20 Orange Approved, Nutraceutical Phase 4
Thyme Approved, Nutraceutical Phase 4
Maleic acid Experimental Phase 4,Phase 3 110-16-7 444266
BCG vaccine Investigational Phase 4
24 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2
25 Hormone Antagonists Phase 4,Phase 3
26 Hormones Phase 4,Phase 3
27 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3
28 Leukotriene Antagonists Phase 4,Phase 3
29 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
30 Antifungal Agents Phase 4
31 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
Sodium Benzoate Phase 4
33 Analgesics Phase 4,Phase 3,Phase 2
34 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2
35 Antipyretics Phase 4,Phase 3,Phase 2
36 Central Nervous System Stimulants Phase 4,Phase 3
37 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
38 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
39 Anti-Inflammatory Agents Phase 4,Phase 3
40 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1
42 Anti-Allergic Agents Phase 4,Phase 3,Phase 2,Phase 1
43 Antipruritics Phase 4,Phase 3,Phase 2,Phase 1
Chlorpheniramine Phase 4,Phase 3,Phase 2 113-92-8, 132-22-9 2725
45 Chlorpheniramine, phenylpropanolamine drug combination Phase 4,Phase 3,Phase 2
46 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
47 Histamine Antagonists Phase 4,Phase 3,Phase 1
48 Histamine H1 Antagonists Phase 4,Phase 3,Phase 1
Histamine Phosphate Phase 4,Phase 3,Phase 1 51-74-1 65513
50 Nasal Decongestants Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 207)

id Name Status NCT ID Phase Drugs
1 A Study of Arbidol (Umifenovir) for Treatment and Prophylaxis of Influenza and Common Cold Unknown status NCT01651663 Phase 4 Arbidol (Umifenovir);Arbidol (Umifenovir)
2 Singulair Use in Non-Allergic Rhinitis Eosinophil Syndrome (NARES) Unknown status NCT00406094 Phase 4 montelukast;placebo
3 Bromelin, a Compound Prepared With Ananas Comocus Extract and Honey, for Acute Cough Unknown status NCT01356693 Phase 4 Bromelin;Placebo
4 Montelukast for Persistent Cough in Young People and Adults Unknown status NCT01279668 Phase 4 Montelukast;Placebo
5 Effects of a Common Cold Treatment on Cognitive Function Completed NCT01466348 Phase 4 Paracetamol and Caffeine;Paracetamol
6 Symptomatic Treatment of Common Cold Symptoms Completed NCT01033526 Phase 4 Aspirin (Acetylsalicylic acid, BAYE4465);Placebo
7 Safety Trial of Atrovent® in Pediatric Patients With Rhinorrhea Associated With a Common Cold or Allergy Completed NCT02238210 Phase 4 Atrovent®
8 Iota-Carrageenan Nasal Spray in Common Cold Completed NCT01944631 Phase 4
9 The Effect of Paracetamol, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Tablets Compared to Placebo in Subjects Suffering From the Common Cold or Influenza. Completed NCT02246166 Phase 4 Test tablet
10 Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Throat Associated With a Common Cold Completed NCT01465009 Phase 4 Acetylsalicylic acid (Aspirin, BAYE4465);Paracetamol;Placebo
11 Efficacy and Safety of Sinutab on Subjects in the Setting of a Common Cold Completed NCT00378144 Phase 4 Pseudoephedrine/Paracetamol
12 A Comparison of Solid and Soluble Forms of Cold and Influenza Remedies Completed NCT01332578 Phase 4 Paracetamol;Phenylephrine;Ascorbic Acid
13 Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction Completed NCT01847131 Phase 4 oxymetazoline;Placebo nasal spray
14 Effectiveness of a Handwashing Programme in the Prevention of School Absenteeism Due to Respiratory Infections Completed NCT01728090 Phase 4
15 Comparison of Efficacy and Tolerability of Two Cough Syrups in Cough Due to Cold in Children. Completed NCT01968434 Phase 4 carbocisteine cough syrup
16 Efficacy and Safety Study of Ingavirin® 90 mg Once Daily to Treat Influenza and Other Acute Viral Infections in Adults Completed NCT03154515 Phase 4 Ingavirin;Placebo
17 Efficacy and Safety of Imuneks 10 mg Capsules in the Prophylaxis of Cold Completed NCT02807220 Phase 4 Imuneks 10mg
18 Evaluate the Potential of Montelukast to Prevent Nasal Symptomatology During Colds Completed NCT00189475 Phase 4 Montelukast
19 Echinacea Safety Study Completed NCT01021995 Phase 4 echinacea;placebo
20 Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. Completed NCT01694108 Phase 4
21 Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis Completed NCT00000411 Phase 4
22 Prevention of RSV Infections in Bone Marrow Transplant Recipients Completed NCT00001903 Phase 4 RSV Polyclonal Immunoglobulin
23 Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis Completed NCT00979615 Phase 4 Olopatadine HCL (Patanase) Nasal Spray, 0.6%;Azelastine HCl (Astelin) Nasal Spray, 137 mcg
24 Effect of OM-85 BV on Wheezing Related Morbidity in Children With Recurrent Wheezing Completed NCT00733226 Phase 4 OM-85 BV (Broncho-Vaxom);OM-85 BV (placebo)
25 Trial of Chinese Herbal Medicine in the Treatment of Upper Respiratory Tract Infections (URTIs) Completed NCT00887172 Phase 4 Jing Fang Bai Du san;Placebo;Ying Qiao san
26 Placebo and Active Controlled Study to Compare the Antipyretic Efficacy of Aspirin® in Patients With Acute Febrile Upper Respiratory Tract Infections Suspected to be of Viral Origin Completed NCT01464944 Phase 4 Acetylsalicylic acid (Aspirin, BAYE4465);Acetylsalicylic acid (Aspirin, BAYE4465);Paracetamol;Paracetamol;Placebo
27 Echinaforce Junior Bioavailability Trial Recruiting NCT03070314 Phase 4 Echinaforce junior
28 Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis Recruiting NCT02288156 Phase 4 Capsaicin;placebo
29 Dextromethorphan Pediatric Acute Cough Study Recruiting NCT02651116 Phase 4 Dextromethorphan Hydrobromide;Placebo
30 PEAC: Phytus Efficacy in Acute Cough Not yet recruiting NCT02981147 Phase 4 Phytus (Cisti, Thyme and Ivy Leaves)
31 Effect of Oxymetazoline Hydrochloride in Comibination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea Not yet recruiting NCT02630121 Phase 4 Oxymetazoline Hydrochloride;Placebo
32 Acute Cough Study In Children Terminated NCT01257542 Phase 4 Dextromethorphan;Placebo
33 Study Of RV-39 In Patients Who Also Have Asthma Terminated NCT00503009 Phase 4 fluticasone propionate/salmeterol;fluticasone propionate;placebo
34 Efficacy and Safety Assessment of an Anti-Cold Preparation in the Symptomatic Treatment of Common Cold and Flu-Like Syndrome Unknown status NCT00940836 Phase 3 Resfenol;Placebo;Co interventional acetaminophen
35 Efficacy of Nasal Naphazoline Hydrocloride + Pheniramine Maleate + Panthenol Compared With Naphazoline Hydrocloride in the Symptomatic Control of Nasal Congestion and Nasopharyngeal Unknown status NCT01533220 Phase 3 naphazoline hydrocloride;Naphazoline hydrocloride + Pheniramine Maleate + Panthenol
36 Effectiveness and Safety of the of Guaifenesin, Doxylamine Succinate and Hydrochloride Etafedrine Syrup in Improvement of Symptoms Resulting From Acute Respiratory Infections. Unknown status NCT00857987 Phase 3 EMS Expectorant
37 Mepolizumab Treatment for Rhinovirus-induced Asthma Exacerbations Unknown status NCT01520051 Phase 3 Mepolizumab;Placebo
38 Montelukast as Prophylaxis for Upper Respiratory Tract Infections in Children: a Randomised, Double-blind, Placebo-controlled Study Unknown status NCT00551382 Phase 3 Muntelukast;Placebo
39 Decongestant Effect, Timing of Effect and Impact on Sleep and General Well-Being of Xylometazoline in Subjects With a Common Cold Completed NCT00452270 Phase 3 Xylometazoline
40 Effects of Two Doses of a Common Cold Treatment on Alertness Completed NCT01686646 Phase 3 paracetamol + caffeine;paracetamol
41 Echinacea Versus Placebo Effect in Common Cold (Physician Echinacea Placebo) Completed NCT00065715 Phase 3
42 Evaluation of Efficacy and Safety of Oral Solution Resfenol in Reducing Symptoms of Common Cold And Flu Completed NCT01158326 Phase 3 Resfenol
43 A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold Completed NCT01744106 Phase 3 pseudoephedrine hydrochloride 30 mg tablets;Placebo tablets
44 Pomegranate Products for Prevention of Common Cold Completed NCT00617318 Phase 3
45 Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common Cold Completed NCT01361399 Phase 3 Acetylsalicylic acid (Aspirin, BAYE4465) & Lidocain;Acetylsalicylic Acid (Aspirin, BAYE4465);Lidocain;Placebo
46 Efficacy and Safety of Paracetamol, Chlorpheniramine and Phenylephrine in the Treatment of Common Cold and Flu Syndrome Completed NCT01389518 Phase 3 Active;Placebo
47 Acetylsalicylic Acid Combined With Pseudoephedrine in Common Cold Completed NCT00963443 Phase 3 Acetylsalicylic Acid (Aspirin, BAYE4465);Pseudoephedrine;Placebo
48 Efficacy and Safety of a Sore Throat Lozenge Containing Lidocaine and Cetylpyridinium Chloride in Patients With Sore Throat Due to a Common Cold. Completed NCT01265446 Phase 3 Lidocaine 8mg + CPC 2mg;Lidocaine 1mg + CPC 2mg
49 Safety and Intake Effect of EPs® 7630 (an Extract of the Roots of Pelargonium Sidoides) Completed NCT02174653 Phase 3 EPs® 7630;Placebo
50 Study to Evaluate the Safety and Tolerability of a Nasal Spray in Patients With Chronic Allergic or Nonallergic Rhinitis Completed NCT00783432 Phase 3 Astepro Nasal Spray (0.1% azelastine hydrochloride);Astelin Nasal Spray (0.1% azelastine hydrochloride)

Search NIH Clinical Center for Common Cold

Inferred drug relations via UMLS 69 / NDF-RT 48 :

Cochrane evidence based reviews: common cold

Genetic Tests for Common Cold

Anatomical Context for Common Cold

MalaCards organs/tissues related to Common Cold:

Eye, Testes, Bone, Bone Marrow, T Cells, Lung, Monocytes

Publications for Common Cold

Articles related to Common Cold:

(show top 50) (show all 575)
id Title Authors Year
MEWDS, Common Cold of the Retina. ( 28540002 )
Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage. ( 28515951 )
Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold: CHEST Expert Panel Report. ( 28837801 )
Heated, humidified air for the common cold. ( 28849871 )
Is Corticosteroid of No Use for Pediatric Patients with Common Cold Undergoing Anesthesia? A Randomized, Double-Blind, Clinical Trial. ( 28824868 )
Vaccines for the common cold. ( 28516442 )
Offspring of parents who were separated and not speaking to one another have reduced resistance to the common cold as adults. ( 28584098 )
Duration of the common cold and similar continuous outcomes should be analyzed on the relative scale: a case study of two zinc lozenge trials. ( 28494765 )
Rhinovirus - not just the common cold. ( 28646961 )
Zinc Acetate Lozenges May Improve the Recovery Rate of Common Cold Patients: An Individual Patient Data Meta-Analysis. ( 28480298 )
Trend Of Irrational Medication Among The Students Of Department Of Pharmacy Abbottabad University Of Science And Technology In Common Cold And Flu. ( 28712182 )
Hopes and challenges for the common cold. ( 28238227 )
Common cold among pre-school children in China - associations with ambient PM10 and dampness, mould, cats, dogs, rats and cockroaches in the home environment. ( 28351766 )
Efficacy and safety of Lian-Ju-Gan-Mao capsules for treating the common cold with wind-heat syndrome: study protocol for a randomized controlled trial. ( 28057058 )
How does rhinovirus cause the common cold cough? ( 26835135 )
Two interferon-independent double-stranded RNA-induced host defense strategies suppress the common cold virus at warm temperature. ( 27402752 )
Prevention and Treatment of Influenza, Influenza-Like Illness, and Common Cold by Herbal, Complementary, and Natural Therapies. ( 27055821 )
Factors associated with efficacy of an ibuprofen/pseudoephedrine combination drug in pharmacy customersA with common cold symptoms. ( 27925348 )
Notice of Retraction: Das RR, Singh M. Oral Zinc for the Common Cold. JAMA. 2014;311(14):1440-1441. ( 28027374 )
Common Cold - an Umbrella Term for Acute Infections of Nose, Throat, Larynx and Bronchi. ( 27912214 )
Viral entry pathways: the example of common cold viruses. ( 27174165 )
Characterization of urge to cough and cough symptoms associated with the common cold: results of a US internet survey. ( 27177045 )
Zinc acetate lozenges for treating the common cold: an individual patient data meta-analysis. ( 27378206 )
Thomas Chalmers, vitamin C and the common cold. ( 26880652 )
Nasal decongestants in monotherapy for the common cold. ( 27748955 )
Knowledge, Attitude And Practice Of Common Cold And Its Management Among Doctors Of Pakistan. ( 28712227 )
Many continuous variables such as the duration of the common cold should be analyzed using the relative scale. ( 27060387 )
Effects of Lactobacillus casei Shirota ingestion on common cold infection and herpes virus antibodies in endurance athletes: a placebo-controlled, randomized trial. ( 27294502 )
Echinacea purpurea: A Proprietary Extract of Echinacea purpurea Is Shown to be Safe and Effective in the Prevention of the Common Cold. ( 26633727 )
Dispositional Affect Moderates the Stress-Buffering Effect of Social Support on Risk for Developing the Common Cold. ( 27468129 )
Analysis of a common cold virus and its subviral particles by gas-phase electrophoretic mobility molecular analysis and native mass spectrometry. ( 26221912 )
Behaviorally Assessed Sleep and Susceptibility to the Common Cold. ( 26118561 )
Usage of Over-the-Counter and Herbal Products in Common Cold in Poland: Findings from Consumer Survey. ( 26285612 )
Self-medication for cough and the common cold: information needs of consumers. ( 26590496 )
Impact of cough and common cold on productivity, absenteeism, and daily life in the United States: ACHOO Survey. ( 26073933 )
The effectiveness of high dose zinc acetate lozenges on various common cold symptoms: a meta-analysis. ( 25888289 )
Compound Formulas of Traditional Chinese Medicine for the Common Cold: Systematic Review of Randomized, Placebo-controlled Trials. ( 26567449 )
Common Cold Treatment Using Zinc--Reply. ( 26284729 )
Corticosteroids for the common cold. ( 26461493 )
Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells. ( 25561542 )
Non-steroidal anti-inflammatory drugs for the common cold. ( 26387658 )
Self-Rated Health in Healthy Adults and Susceptibility to the Common Cold. ( 26397938 )
Efficacy and safety of iota-carrageenan nasal spray versus placebo in early treatment of the common cold in adults: the ICICC trial. ( 26438038 )
Tear Fluid SIgA as a Noninvasive Biomarker of Mucosal Immunity and Common Cold Risk. ( 26496418 )
Re: "Zinc lozenges and vitamin C for the common cold are not examples of placebo effect in action". ( 26279402 )
Antihistamines for the common cold. ( 26615034 )
Treatment of Acute Cough Due to the Common Cold: Multi-component, Multi-symptom Therapy is Preferable to Single-Component, Single-Symptom Therapy-A Pro/Con Debate. ( 26420163 )
Heterogeneity in the prognosis of major depression: from the common cold to a highly debilitating and recurrent illness. ( 26081748 )
Overuse of antibiotics for the common cold - attitudes and behaviors among doctors in rural areas of Shandong Province, China. ( 25884702 )
Zinc lozenges and vitamin C for the common cold are not examples of placebo effect in action. ( 26071891 )

Variations for Common Cold

Expression for Common Cold

Search GEO for disease gene expression data for Common Cold.

Pathways for Common Cold

Pathways related to Common Cold according to GeneCards Suite gene sharing:

(show all 35)
id Super pathways Score Top Affiliating Genes
Show member pathways
Show member pathways
13.62 CCL11 CCL5 CXCL8 IFNA2 IL13 IL1R1
Show member pathways
Show member pathways
13.37 CCL11 CCL5 CXCL8 IL13 IL1R1 IL4
Show member pathways
Show member pathways
13.25 CCL11 CCL5 CXCL8 IL13 IL1R1 IL4
Show member pathways
12.95 CCL5 CXCL8 IFNA2 IL1R1 IL33 TLR9
Show member pathways
12.75 CCL11 CXCL8 ICAM1 IFNA2 IL13 IL4
Show member pathways
12.66 CCL5 CXCL8 ICAM1 IFNA2 IL13 IL33
Show member pathways
12.32 CCL11 CXCL8 IL13 IL4 IL5
Show member pathways
12.29 CCL11 CCL5 CXCL8 ICAM1
Show member pathways
12.21 IFNA2 IL13 IL4 IL5 TSLP
Show member pathways
12.17 CCL11 CXCL8 IL1R1 IL4 TLR9
Show member pathways
12.13 CXCL8 IFNA2 IL13 IL4 IL5
Show member pathways
12.01 IL13 IL1R1 IL5 TLR9
16 11.99 CXCL8 ICAM1 IL1R1 IL4 SELP
17 11.95 CCL11 CXCL8 ICAM1 IL13 IL4
Show member pathways
11.84 IL1R1 IL4 TLR9
19 11.83 IL1R1 IL4 IL5
20 11.82 CXCL8 ICAM1 IL1R1
21 11.79 CCL5 CXCL8 ICAM1
22 11.74 CXCL8 ICAM1 IL13 IL4 IL5
23 11.73 ICAM1 IL4 IL5 TLR9
Show member pathways
11.71 CXCL8 IL4 IL5
25 11.67 CCL11 IL4 IL5 SELP
26 11.54 IL13 IL1R1 IL33 IL4 IL5 TSLP
27 11.53 CXCL8 ICAM1 SELP TLR9
28 11.39 CCL11 IL13 IL33 IL4 IL5
29 11.26 IL13 IL4 IL5
30 11.23 CCL11 CCL5 CXCL8 IL13 IL4 IL5
31 11.19 IL13 IL4 IL5
32 11.16 CCL11 CCL5 CXCL8 IL13 IL4 IL5
33 11.16 IL13 IL33 IL4 IL5 TSLP
34 10.9 IL13 IL4 IL5
35 10.79 CCL5 CXCL8 ICAM1 IL13 IL1R1 IL4

GO Terms for Common Cold

Cellular components related to Common Cold according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.8 ALB CCL11 CCL5 CXCL8 IFNA2 IL13
2 external side of plasma membrane GO:0009897 9.55 ICAM1 IL13 IL4 LDLR SELP
3 extracellular space GO:0005615 9.55 ALB CCL11 CCL5 CXCL8 ICAM1 IFNA2
4 endolysosome membrane GO:0036020 9.26 LDLR TLR9

Biological processes related to Common Cold according to GeneCards Suite gene sharing:

(show all 29)
id Name GO ID Score Top Affiliating Genes
1 chemotaxis GO:0006935 9.81 CCL11 CCL5 CXCL8 IL4
2 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.8 ICAM1 IL4 IL5
3 cholesterol metabolic process GO:0008203 9.8 IL4 LDLR VLDLR
4 immune response GO:0006955 9.8 CCL11 CCL5 CXCL8 IL13 IL1R1 IL4
5 chemokine-mediated signaling pathway GO:0070098 9.77 CCL11 CCL5 CXCL8
6 cellular response to tumor necrosis factor GO:0071356 9.76 CCL11 CCL5 CXCL8 ICAM1
7 neutrophil chemotaxis GO:0030593 9.74 CCL11 CCL5 CXCL8
8 positive regulation of inflammatory response GO:0050729 9.73 IL33 LDLR TLR9
9 cellular response to interferon-gamma GO:0071346 9.71 CCL11 CCL5 ICAM1
10 cellular response to interleukin-1 GO:0071347 9.67 CCL11 CCL5 CXCL8 ICAM1
11 positive regulation of macrophage activation GO:0043032 9.64 IL13 IL33
12 microglial cell activation GO:0001774 9.64 IL13 IL4
13 response to molecule of bacterial origin GO:0002237 9.63 CXCL8 TLR9
14 positive regulation of immunoglobulin secretion GO:0051024 9.62 IL33 IL5
15 negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 9.61 CCL5 CXCL8
16 defense response to Gram-negative bacterium GO:0050829 9.61 SELP TLR9
17 negative regulation of endothelial cell apoptotic process GO:2000352 9.61 ICAM1 IL13 IL4
18 positive regulation of mast cell degranulation GO:0043306 9.6 IL13 IL4
19 neutrophil activation GO:0042119 9.58 CCL5 CXCL8
20 eosinophil chemotaxis GO:0048245 9.58 CCL11 CCL5
21 leukocyte cell-cell adhesion GO:0007159 9.58 CCL5 ICAM1 SELP
22 positive regulation of interleukin-13 production GO:0032736 9.55 IL33 IL4
23 type 2 immune response GO:0042092 9.52 IL33 IL4
24 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.5 CCL5 IFNA2 IL4
25 regulation of proton transport GO:0010155 9.49 IL13 IL4
26 negative regulation of complement-dependent cytotoxicity GO:1903660 9.48 IL13 IL4
27 inflammatory response GO:0006954 9.23 CCL11 CCL5 CXCL8 IFNA2 IL13 IL5
28 positive regulation of immunoglobulin production GO:0002639 9.16 IL13 IL4
29 positive regulation of B cell proliferation GO:0030890 9.13 IL13 IL4 IL5

Molecular functions related to Common Cold according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.43 CCL11 CCL5 CXCL8
2 low-density lipoprotein receptor activity GO:0005041 9.32 LDLR VLDLR
3 cytokine activity GO:0005125 9.28 CCL11 CCL5 CXCL8 IFNA2 IL13 IL33
4 very-low-density lipoprotein particle receptor activity GO:0030229 9.16 LDLR VLDLR
5 cytokine receptor binding GO:0005126 9.13 IFNA2 IL13 IL4

Sources for Common Cold

9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
32 HPO
33 ICD10
34 ICD10 via Orphanet
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
52 Novoseek
55 OMIM via Orphanet
59 PubMed
66 SNOMED-CT via Orphanet
68 Tocris
70 UMLS via Orphanet
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