Aliases & Classifications for Common Wart

Summaries for Common Wart

Disease Ontology : 12 A viral infectious disease that results_in infection located in skin, has material basis in human papillomavirus (types 2 and 4). This infection has symptom raised wart with roughened surface, most common on hands, but can grow anywhere on the body.

MalaCards based summary : Common Wart is related to haemophilus influenzae and mycobacterium abscessus, and has symptoms including raised wart An important gene associated with Common Wart is CLEC7A (C-Type Lectin Domain Containing 7A), and among its related pathways/superpathways are Innate Immune System and Toll-Like receptor Signaling Pathways. The drugs Miconazole and Salicylic acid have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and testes, and related phenotypes are hematopoietic system and immune system

Related Diseases for Common Wart

Graphical network of the top 20 diseases related to Common Wart:



Diseases related to Common Wart

Symptoms & Phenotypes for Common Wart

Symptoms:

12
  • raised wart

MGI Mouse Phenotypes related to Common Wart:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 CD40 CD80 CLEC4E CLEC6A CLEC7A LGALS3
2 immune system MP:0005387 9.17 CD40 CD80 CLEC4E CLEC6A CLEC7A LGALS3

Drugs & Therapeutics for Common Wart

Drugs for Common Wart (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 133)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 22916-47-8 4189
2
Salicylic acid Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 69-72-7 338
3
Imiquimod Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 99011-02-6 57469
4
Zinc Approved, Investigational Phase 4,Phase 2,Phase 3 7440-66-6 32051 23994
5
Fluorouracil Approved Phase 4 51-21-8 3385
6 Analgesics Phase 4,Phase 2,Phase 3
7 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 3
8 Antifungal Agents Phase 4,Phase 2,Phase 3
9 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1
10 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3
11 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 2,Phase 3
12 Antirheumatic Agents Phase 4,Phase 2,Phase 3
13 Cyclooxygenase Inhibitors Phase 4,Phase 2,Phase 3
14 Dermatologic Agents Phase 4,Phase 2,Phase 3
15 Keratolytic Agents Phase 4,Phase 2,Phase 3
16 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
17 Salicylates Phase 4,Phase 2,Phase 3
18 Liver Extracts Phase 4,Phase 3
19 Vaccines Phase 4,Phase 3,Phase 2,Phase 1
20 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
21 Adjuvants, Immunologic Phase 4,Phase 3,Phase 2,Phase 1
22 Interferon Inducers Phase 4,Phase 3,Phase 2,Phase 1
23 interferons Phase 4,Phase 3,Phase 2,Phase 1
24 Antibodies Phase 4,Phase 1
25 Immunoglobulins Phase 4,Phase 1
26 Micronutrients Phase 4,Phase 2,Phase 3
27 Trace Elements Phase 4,Phase 2,Phase 3
28 Antimetabolites Phase 4,Phase 1,Phase 2
29 Antimetabolites, Antineoplastic Phase 4,Phase 1,Phase 2
30 pyruvate Nutraceutical Phase 4,Phase 2,Phase 3
31
Catechin Nutraceutical Phase 4,Phase 1 154-23-4 9064
32
Epicatechin Investigational, Nutraceutical Phase 4,Phase 1 490-46-0 72276
33 Tea Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1
34
Ethanol Approved Phase 2, Phase 3 64-17-5 702
35
Petrolatum Approved, Investigational Phase 2, Phase 3 8009-03-8
36
Aminolevulinic acid Approved Phase 3 106-60-5 137
37
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
38
Pancrelipase Approved, Investigational Phase 3 53608-75-6
39
Benzocaine Approved, Investigational Phase 3 1994-09-7, 94-09-7 2337
40
Furosemide Approved, Vet_approved Phase 3,Phase 2 54-31-9 3440
41
Lenograstim Approved, Investigational Phase 3 135968-09-1
42 Zinc sulfate Approved, Investigational Phase 3 7733-02-0
43 tannic acid Approved, Nutraceutical Phase 3
44 Pharmaceutical Solutions Phase 2, Phase 3, Phase 1
45 Alkylating Agents Phase 3
46 Methyl 5-aminolevulinate Phase 3
47 Photosensitizing Agents Phase 3
48 pancreatin Phase 3
49 Anti-HIV Agents Phase 3,Phase 1
50 Anti-Retroviral Agents Phase 3,Phase 1

Interventional clinical trials:

(show top 50) (show all 185)

# Name Status NCT ID Phase Drugs
1 17% Salicylate Versus 17% Salicylate-Ethyl Pyruvate for Plantar Foot Warts Unknown status NCT01712295 Phase 4 17% Salicylate with ethyl pyruvate;Salicylates
2 Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls? Unknown status NCT01101750 Phase 4
3 Imiquimod 5% Cream in the Treatment of External Genital or Perianal Warts in HIV+ Patients Completed NCT00761371 Phase 4 Imiquimod 5% cream
4 Pulsed 1064nm Nd:YAG in the Treatment of Verruca Vulgaris Versus Conventional Therapy With Liquid Nitrogen Cryotherapy Completed NCT01609530 Phase 4
5 Study of Imiquimod Cream Prior to Ablative Therapy in External Ano-Genital Warts Completed NCT00189293 Phase 4 Imiquimod
6 Pharmacokinetic Study of Topically Applied Veregen 15% Compared With Oral Intake of Green Tea Beverage Completed NCT01082302 Phase 4 Polyphenon E (Veregen) 15% ointment
7 Investigating Veregen ™ 15% Ointment Treatment For Non-facial Verrucae in Pediatric Patients: A Pilot Study Completed NCT02622568 Phase 4 Veregen only
8 Alternate Dosing Schedules Study for HPV Vaccine (ADS) Completed NCT02280642 Phase 4
9 Alternate Dosing Schedules Study for HPV Vaccine Completed NCT00862810 Phase 4
10 Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts Recruiting NCT03183765 Phase 4 Measles-Mumps-Rubella Vaccine
11 Scientific Evaluation of One or Two Doses of the Bivalent or Nonavalent Prophylactic HPV Vaccines Recruiting NCT03180034 Phase 4
12 HPV (Human Papilloma Virus) Vaccination After Treatment of Anal Intraepithelial Neoplasia (AIN) Recruiting NCT02087384 Phase 4 Placebo
13 Immunogenicity and Safety of Human Papilloma Virus Vaccine in Solid Organ Transplant Recipients Active, not recruiting NCT02624349 Phase 4 Quadravalent human papillomavirus vaccine
14 A RTC to Examine the Effectiveness of 400 mg of Oral Zinc Gluconate as Adjunctive Therapy for Ano-genital Warts Terminated NCT01468636 Phase 4 Oral Zinc;Placebo
15 Comparison of Five Treatments in Patients With Plantar Warts Terminated NCT01059110 Phase 4 Salicylate ointment;Imiquimod;5-Fluoro-Uracil;Cryotherapy
16 Pyruvic Acid Versus Salicylic Acid Preparation in Treatment of Plantar Warts Unknown status NCT02151630 Phase 2, Phase 3 Pyruvic acid;Salicylic Acid
17 Efficacy of Laser Versus Cryotherapy in the Treatment of Warts Unknown status NCT01808443 Phase 3
18 Topical 5-ALA Photodynamic Therapy for the Treatment of Verruca Vulgaris Unknown status NCT00155584 Phase 3
19 Two-dose Schedule of Quadrivalent HPV Recombinant Vaccine in 11-year-old Boys in Mexico City Unknown status NCT02382900 Phase 3
20 Phase 3 Study of Imiquimod Creams in the Treatment of External Genital Warts Completed NCT00735462 Phase 3 2.5% imiquimod cream;3.75% imiquimod cream;Placebo cream
21 Safety and Effectiveness Study of Imiquimod Creams in the Treatment of External Genital Warts Completed NCT00674739 Phase 3 Imiquimod;3.75% imiquimod cream;placebo cream
22 Oral Zinc Gluconate as Treatment for Recalcitrant Cutaneous Warts: A Randomized, Double-blind, Placebo-controlled Trial Completed NCT01783353 Phase 2, Phase 3
23 Low Dose Cyclophosphamide Treats Genital Warts Completed NCT00999986 Phase 3 cyclophosphamide
24 Glizigen-Viudid-External Anogenital Warts in Children and Adolescents Completed NCT01111344 Phase 3
25 Cervical Intraepithelial Neoplasm (CIN)-Warts Efficacy Trial in Women (Gardasil)(V501-013)(COMPLETED) Completed NCT00092521 Phase 3
26 An Investigational Study of Gardasil™ (qHPV, V501) Vaccine in Reducing the Incidence of Anogenital Warts in Young Men (V501-020) Completed NCT00090285 Phase 3
27 Efficacy and Safety Study of Polyphenon E to Treat External Genital Warts Completed NCT00449982 Phase 3 Polyphenon E Ointment 10%, Polyphenon E Ointment 15%
28 PDT With Metvix® 160 mg/g Cream in Organ Transplant Recipients With Non-melanoma Skin Cancer Completed NCT00472459 Phase 3
29 Study to Test the Safety of HPV Vaccine in Women (V501-011)(COMPLETED) Completed NCT00517309 Phase 3
30 A Controlled Trial to Assess the Immunogenicity of a Proposed Paediatric Dosing Schedule of Human Papillomavirus Vaccine Completed NCT00501137 Phase 3
31 Cervical Intraepithelial Neoplasm (CIN) in Women (Gardasil)(V501-015) Completed NCT00092534 Phase 3
32 Study of an Investigational Vaccine in Pre-Adolescents and Adolescents (Gardasil)(V501-016) Completed NCT00092495 Phase 3
33 Immunogenicity Bridge Between an Investigational Monovalent Vaccine and the Equivalent Component of Gardasil (V501) a Quadrivalent Vaccine (V501-012)(COMPLETED) Completed NCT00092482 Phase 3
34 Evaluation of Long Term Immunity Following HPV Vaccination Completed NCT02276521 Phase 2, Phase 3
35 A Study of V503, a 9-valent Human Papillomavirus (9vHPV) Vaccine in Females 12-26 Years of Age Who Have Previously Received GARDASIL™ (V503-006) Completed NCT01047345 Phase 3
36 Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003) Completed NCT01651949 Phase 3
37 Safety and Immunogenicity of Human Papillomavirus (HPV) Vaccine in Solid Organ Transplant Recipients Completed NCT00677677 Phase 3
38 Protecting Young Special Risk Females From Cervical Cancer Through Human Papilloma Virus (HPV) Vaccination Completed NCT00964210 Phase 3 Licensed quadrivalent HPV vaccine, Gardasil
39 Immunogenicity of GlaxoSmithKline Biological's Human Papillomavirus (HPV) Vaccine (580299) Versus Merck's Gardasil® in Healthy Females 18-45 Years of Age Completed NCT00423046 Phase 3
40 Topical Green Tea Ointment in Treatment of Superficial Skin Cancer Completed NCT02029352 Phase 2, Phase 3 Sinecatechins 10%;Placebo
41 Broad Spectrum HPV (Human Papillomavirus) Vaccine Study in 16-to 26-Year-Old Women (V503-001) Completed NCT00543543 Phase 3
42 A Study to Evaluate the Safety, Immune Response, and Efficacy of Gardasil (V501, qHPV) in Mid-Adult Women (V501-019) Completed NCT00090220 Phase 3
43 GARDASIL™ Study in Healthy Females Between 9 and 26 Years of Age in Sub-Saharan Africa (V501-046) Completed NCT01245764 Phase 3
44 A Study of Gardasil (V501) in Preadolescents and Adolescents (V501-018) Completed NCT00092547 Phase 3
45 A Study to Evaluate the Safety and Efficacy of CLS006 Versus Vehicle in Subjects 2 Years of Age or Older With Cutaneous Common Warts Recruiting NCT03259620 Phase 3 CLS006;CLS006 Vehicle
46 Efficacy of Quadrivalent HPV Vaccine to Prevent Relapses of Genital Warts After Initial Therapeutic Response Recruiting NCT03296397 Phase 3
47 Plerixafor Versus G-CSF in the Treatment of People With WHIM Syndrome Recruiting NCT02231879 Phase 3 Plerixafor;G-CSF
48 A Trial of X4P-001 in Patients With WHIM Syndrome Recruiting NCT03005327 Phase 2, Phase 3 X4P-001;Placebo
49 Radiotherapy or Imiquimod in Complex Lentigo Maligna Recruiting NCT02394132 Phase 3 Imiquimod
50 Immunogenicity and Tolerability of Broad Spectrum Human Papillomavirus (HPV) Vaccine in Adult and Young Adult Women (V503-004) Recruiting NCT03158220 Phase 3

Search NIH Clinical Center for Common Wart

Genetic Tests for Common Wart

Anatomical Context for Common Wart

The Foundational Model of Anatomy Ontology organs/tissues related to Common Wart:

18
Skin

MalaCards organs/tissues related to Common Wart:

38
Skin, Testes, Liver, Kidney, Bone

Publications for Common Wart

Articles related to Common Wart:

(show all 29)
# Title Authors Year
1
Hyperkeratotic acral melanoma mimicking a common wart. ( 25973355 )
2015
2
Measles, mumps, and rubella vaccine: a new option to treat common warts? ( 23786798 )
2013
3
Keratotic horn on left fifth fingertip: congenital ectopic nail misdiagnosed as a common wart. ( 22277059 )
2013
4
Comparative study of topical 80% trichloroacetic acid with 35% trichloroacetic acid in the treatment of the common wart. ( 23135096 )
2012
5
Intralesional immunotherapy of common warts: successful treatment with mumps, measles and rubella vaccine. ( 20202055 )
2010
6
Treatment options for the common wart. ( 18210913 )
2007
7
Plantar verrucous carcinoma (epithelloma cuniculatum): rare form of the common wart. ( 17214114 )
2006
8
Human leukocyte antigen class II alleles and natural history of HPV 2/27/57-induced common warts. ( 15257408 )
2004
9
Molecular analysis of the effect of topical imiquimod treatment of HPV 2/27/57-induced common warts. ( 15452412 )
2004
10
The efficacy of duct tape vs cryotherapy in the treatment of verruca vulgaris (the common wart). ( 12361440 )
2002
11
Is duct tape occlusion therapy as effective as cryotherapy for the treatment of the common wart? ( 12361441 )
2002
12
Human papillomavirus associated Bowen's disease of the foot: unique clinical features mimicking a common wart. ( 11525958 )
2001
13
Self-administered topical 5% imiquimod for the treatment of common warts and molluscum contagiosum. ( 11069514 )
2000
14
Simultaneously detected aberrant p53 tumor suppressor protein and HPV-DNA localize mostly in separate keratinocytes in anogenital and common warts. ( 8734914 )
1996
15
Efficacious treatment of the common wart (verruca vulgaris). ( 1462533 )
1992
16
[Systemic treatment of common warts with beta-interferon]. ( 1917463 )
1991
17
Common wart causing longitudinal groove in nail. ( 28150682 )
1986
18
Characterization of two HPV-3 related papillomaviruses from common warts that are distinct clinically from flat warts or epidermodysplasia verruciformis. ( 6302170 )
1983
19
Transformation of the common wart into squamous cell carcinoma in a patient with primary lymphedema. ( 7248909 )
1981
20
Stump the experts. A common wart. ( 7338585 )
1981
21
An unusual transformation of a common wart in a child. ( 6269499 )
1981
22
The common wart: intralesional treatment with bleomycin sulfate. ( 6159138 )
1980
23
Treatment of the common wart by induced allergic inflammation. ( 7389963 )
1980
24
Treatment of the common wart with a virus vaccine. ( 14477428 )
1962
25
Morphological characterization of the virus of the human common wart (verruca vulgaris). ( 13785470 )
1961
26
Aralen and plaquenil in treatment of the common wart. ( 13726985 )
1961
27
Common wart conjunctivitis. ( 13196997 )
1954
28
Treatment of the common wart by x-ray therapy. ( 13164671 )
1954
29
Contact x-ray therapy of the common wart. ( 14914174 )
1952

Variations for Common Wart

Expression for Common Wart

Search GEO for disease gene expression data for Common Wart.

Pathways for Common Wart

GO Terms for Common Wart

Biological processes related to Common Wart according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 innate immune response GO:0045087 9.55 CD209 CLEC4E CLEC6A CLEC7A LGALS3
2 neutrophil chemotaxis GO:0030593 9.43 CXCL8 LGALS3
3 T cell activation GO:0042110 9.4 CD80 CLEC7A
4 positive regulation of cytokine secretion GO:0050715 9.37 CLEC4E CLEC6A
5 defense response to protozoan GO:0042832 9.32 CD40 CLEC7A
6 regulation of T cell proliferation GO:0042129 9.26 CD209 LGALS3
7 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.26 CD209 CLEC4E CLEC6A CLEC7A
8 immune system process GO:0002376 9.1 CD209 CD40 CLEC4E CLEC6A CLEC7A LGALS3

Molecular functions related to Common Wart according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 carbohydrate binding GO:0030246 9.02 CD209 CLEC4E CLEC6A CLEC7A LGALS3

Sources for Common Wart

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
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29 HGMD
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32 ICD10
33 ICD10 via Orphanet
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42 MESH via Orphanet
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65 SNOMED-CT via HPO
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67 TGDB
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70 UMLS via Orphanet
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