MCID: CMM003
MIFTS: 48

Common Wart malady

Summaries for Common Wart

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8Disease Ontology, 32MalaCards
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Disease Ontology:8 A viral infectious disease that results in infection located in skin, has material basis in human papillomavirus (types 2 and 4). this infection has symptom raised wart with roughened surface, most common on hands, but can grow anywhere on the body.

MalaCards: Common Wart is related to measles and rubella, and has symptoms including raised wart An important gene associated with Common Wart is HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1), and among its related pathways are Cytokines and Inflammatory Response and Immune response MIF-mediated glucocorticoid regulation. The drugs cantharidin and formaldehyde and the compounds dpa 1 and anaphylatoxin have been mentioned in the context of this disorder. Affiliated tissues include skin and skin, and related mouse phenotypes are nervous system and skeleton.

Aliases & Classifications for Common Wart

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH, 27ICD9CM, 39NCIt
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Aliases & Descriptions:

common wart 8 10 60


Related Diseases for Common Wart

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Common Wart:



Diseases related to common wart

Clinical Features for Common Wart

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Sources:
8Disease Ontology
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Symptoms:

8
  • raised wart

Drugs & Therapeutics for Common Wart

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Genetic Tests for Common Wart

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Anatomical Context for Common Wart

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Sources:
32MalaCards, 14FMA
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MalaCards organs/tissues related to Common Wart:

32
Skin

FMA organs/tissues related to Common Wart:

14
Skin

Animal Models for Common Wart or affiliated genes

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Sources:
36MGI
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MGI Mouse Phenotypes related to Common Wart:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036319.2NFIC, NFIX, HLA-DQB1
2MP:00053909.0NFIX, NFIC, IL6
3MP:00053977.4TP53, IL6, IL8, HLA-DQA1, HLA-DQB1, IFNB1
4MP:00053877.1IFNB1, HLA-DQB1, HLA-DQA1, IL8, IL6, TP53

Publications for Common Wart

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Sources:
50PubMed
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Articles related to Common Wart:

(show all 29)
idTitleAuthorsYear
1
Measles, mumps, and rubella vaccine: a new option to treat common warts? (23786798)
2013
2
Keratotic horn on left fifth fingertip: congenital ectopic nail misdiagnosed as a common wart. (22277059)
2013
3
Comparative study of topical 80% trichloroacetic acid with 35% trichloroacetic acid in the treatment of the common wart. (23135096)
2012
4
Intralesional immunotherapy of common warts: successful treatment with mumps, measles and rubella vaccine. (20202055)
2010
5
Treatment options for the common wart. (18210913)
2007
6
Role of human papilloma virus (HPV) in common and genital warts and its relation to P53 expression. (17496936)
2006
7
Plantar verrucous carcinoma (epithelloma cuniculatum): rare form of the common wart. (17214114)
2006
8
Human leukocyte antigen class II alleles and natural history of HPV 2/27/57-induced common warts. (15257408)
2004
9
Molecular analysis of the effect of topical imiquimod treatment of HPV 2/27/57-induced common warts. (15452412)
2004
10
The efficacy of duct tape vs cryotherapy in the treatment of verruca vulgaris (the common wart). (12361440)
2002
11
Is duct tape occlusion therapy as effective as cryotherapy for the treatment of the common wart? (12361441)
2002
12
Human papillomavirus associated Bowen's disease of the foot: unique clinical features mimicking a common wart. (11525958)
2001
13
Self-administered topical 5% imiquimod for the treatment of common warts and molluscum contagiosum. (11069514)
2000
14
Drug treatment of common STDs: Part II. Vaginal infections, pelvic inflammatory disease and genital warts. (10537386)
1999
15
Simultaneously detected aberrant p53 tumor suppressor protein and HPV-DNA localize mostly in separate keratinocytes in anogenital and common warts. (8734914)
1996
16
Efficacious treatment of the common wart (verruca vulgaris). (1462533)
1992
17
Systemic treatment of common warts with beta-interferon]. (1917463)
1991
18
Characterization of two HPV-3 related papillomaviruses from common warts that are distinct clinically from flat warts or epidermodysplasia verruciformis. (6302170)
1983
19
An unusual transformation of a common wart in a child. (6269499)
1981
20
Transformation of the common wart into squamous cell carcinoma in a patient with primary lymphedema. (7248909)
1981
21
Stump the experts. A common wart. (7338585)
1981
22
The common wart: intralesional treatment with bleomycin sulfate. (6159138)
1980
23
Treatment of the common wart by induced allergic inflammation. (7389963)
1980
24
Treatment of the common wart with a virus vaccine. (14477428)
1962
25
Morphological characterization of the virus of the human common wart (verruca vulgaris). (13785470)
1961
26
Aralen and plaquenil in treatment of the common wart. (13726985)
1961
27
Treatment of the common wart by x-ray therapy. (13164671)
1954
28
Common wart conjunctivitis. (13196997)
1954
29
Contact x-ray therapy of the common wart. (14914174)
1952

Genetic Variations for Common Wart

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Expression for genes affiliated with Common Wart

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Common Wart

Search GEO for disease gene expression data for Common Wart.

Pathways for genes affiliated with Common Wart

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Sources:
37NCBI BioSystems Database, 12EMD Millipore, 53Reactome, 51QIAGEN, 29KEGG, 55SinoBiological, 52R&D Systems
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Pathways related to Common Wart according to GeneCards/GeneDecks:

(show all 43)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.0HLA-DRB1
29.5IL6, IL8
39.5IL6, IL8
49.3TP53, IL6
5
Immune response NFAT in immune response
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9.3HLA-DQA1, HLA-DRB1, HLA-DQB1
6
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9.3HLA-DQA1, HLA-DRB1, HLA-DQB1
7
Hide members
9.3HLA-DQA1, HLA-DRB1, HLA-DQB1
89.3HLA-DQB1, HLA-DRB1, HLA-DQA1
99.3HLA-DQA1, HLA-DRB1, HLA-DQB1
109.3HLA-DQA1, HLA-DRB1, HLA-DQB1
11
Hide members
9.3HLA-DQB1, HLA-DRB1, HLA-DQA1
12
Hide members
9.3HLA-DQA1, HLA-DRB1, HLA-DQB1
139.3HLA-DQB1, HLA-DRB1, HLA-DQA1
149.3HLA-DQA1, HLA-DRB1, HLA-DQB1
15
Hide members
9.3HLA-DQA1, HLA-DRB1, HLA-DQB1
169.3HLA-DQB1, HLA-DRB1, HLA-DQA1
17
Immune response ICOS pathway in T-helper cell
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9.3HLA-DQB1, HLA-DRB1, HLA-DQA1
18
Immune response Antigen presentation by MHC class II
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9.3HLA-DQA1, HLA-DRB1, HLA-DQB1
199.3HLA-DQB1, HLA-DRB1, HLA-DQA1
20
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9.3HLA-DQB1, HLA-DRB1, HLA-DQA1
219.2IL8, IFNB1
22
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9.2TP53, HLA-DQA1, HLA-DQB1
239.1IL6, IFNB1
24
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9.0TP53, IFNB1
25
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8.9IL8, IL6, TP53
268.9TP53, IL6, IL8
278.9TP53, IL6, IL8
28
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8.8IL6, HLA-DQA1, HLA-DRB1, HLA-DQB1
29
Hide members
8.8HLA-DQB1, HLA-DRB1, HLA-DQA1, IL6
308.7IL6, IL8, IFNB1
31
Hide members
8.7IFNB1, IL8, IL6
328.7IFNB1, IL8, IL6
338.7HLA-DQB1, HLA-DRB1, HLA-DQA1, TP53
348.6TP53, IL8, IFNB1
358.6TP53, IL8, IFNB1
368.2TP53, IL6, HLA-DQA1, HLA-DRB1, HLA-DQB1
37
Hide members
8.2TP53, IL6, HLA-DQA1, HLA-DRB1, HLA-DQB1
38
Hide members
8.1IFNB1, IL8, IL6, TP53
39
Hide members
8.1IFNB1, IL8, IL6, TP53
408.0IFNB1, HLA-DQB1, HLA-DRB1, HLA-DQA1, IL6
41
Hide members
8.0IFNB1, HLA-DQB1, HLA-DRB1, HLA-DQA1, IL6
42
Hide members
8.0IL6, HLA-DQA1, HLA-DRB1, HLA-DQB1, IFNB1
43
Hide members
6.9TP53, IL6, IL8, HLA-DQA1, HLA-DRB1, HLA-DQB1

Compounds for genes affiliated with Common Wart

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Sources:
44Novoseek, 11DrugBank, 49PharmGKB, 28IUPHAR, 2BitterDB, 59Tocris Bioscience, 24HMDB
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Compounds related to Common Wart according to GeneCards/GeneDecks:

(show all 49)
idCompoundScoreTop Affiliating Genes
1dpa 14410.1HLA-DRB1, HLA-DQA1
2anaphylatoxin4410.1IL8
3emedastine44 1111.0IL6, IL8
4tepoxalin4410.0IL8, IL6
5cycloheximide4410.0IFNB1
6lapatinib44 49 1112.0HLA-DQA1, HLA-DRB1
7sivelestat4410.0IL8, IL6
8rebamipide449.9IL6, IL8
9olopatadine44 1110.9IL8, IL6
10taurine chloramine449.9IL8, IL6
11gabexate mesilate449.9IL6, IL8
12u0126449.9IL8, IL6
13mcp 1449.9IL8, IL6
14gold sodium thiomalate449.9HLA-DRB1, IL8
15hbd2449.9IL8, IL6
16mip 1alpha449.9IL6, IL8
17il-12449.8IL8, IL6
18tpck449.7IL8, IL6
19polymyxin b449.5IL8, IL6
20glatiramer acetate44 1110.5IFNB1, HLA-DRB1
21flagellin44 2810.5IFNB1, IL8
22groalpha449.4IL6, IL8
23acnu449.4TP53, IFNB1
24triptolide449.4IL8, IL6, TP53
25parthenolide44 210.4TP53, IL6, IL8
26hpvs449.4TP53, IFNB1
27pdtc449.3TP53, IL6, IL8
28sp 60012544 5910.3TP53, IL6, IL8
29rantes449.2IL6, IFNB1
30temozolomide44 1110.2TP53, IFNB1
31curcumin449.2TP53, IL6, IL8
32hcec449.2IL6, IL8, IFNB1
33imiquimod44 28 59 1112.2IL6, IL8, IFNB1
34lipoteichoic acid449.2IL6, IL8, IFNB1
35polyinosinic-polycytidylic acid449.2IFNB1, IL8, IL6
36poly(i-c)449.2IL6, IL8, IFNB1
37il 10449.2IFNB1, IL8, IL6
38peptidoglycan44 2810.1IL6, IL8, IFNB1
39ccl344 2810.1IL6, IL8, IFNB1
40neopterin449.1IL6, IL8, IFNB1
41simvastatin44 49 59 28 11 2414.1IL6, IL8, IFNB1
42herbimycin a44 5910.1IFNB1, IL8, IL6
43methotrexate44 49 1110.9IL6, HLA-DRB1, IFNB1
44n acetylcysteine448.6TP53, IL6, IL8
45sb 20358044 599.5IFNB1, IL8, IL6, TP53
46ly294002448.5IFNB1, IL8, IL6, TP53
47actinomycin d448.5IFNB1, IL8, IL6, TP53
48oligonucleotide448.3TP53, HLA-DQA1, HLA-DRB1, HLA-DQB1, IFNB1
49vegf448.2TP53, IL6, IL8, IFNB1

GO Terms for genes affiliated with Common Wart

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Sources:
16Gene Ontology
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Cellular components related to Common Wart according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:0426139.5HLA-DQA1, HLA-DRB1, HLA-DQB1
2clathrin-coated endocytic vesicle membraneGO:0306699.5HLA-DQA1, HLA-DRB1, HLA-DQB1
3integral to lumenal side of endoplasmic reticulum membraneGO:0715569.4HLA-DQB1, HLA-DRB1, HLA-DQA1
4transport vesicle membraneGO:0306589.4HLA-DQB1, HLA-DRB1, HLA-DQA1
5ER to Golgi transport vesicle membraneGO:0125079.3HLA-DQB1, HLA-DRB1, HLA-DQA1
6lysosomal membraneGO:0057659.3HLA-DQA1, HLA-DRB1, HLA-DQB1
7trans-Golgi network membraneGO:0325889.2HLA-DQA1, HLA-DRB1, HLA-DQB1
8endocytic vesicle membraneGO:0306669.0HLA-DQB1, HLA-DRB1, HLA-DQA1

Biological processes related to Common Wart according to GeneCards/GeneDecks:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1immunoglobulin production involved in immunoglobulin mediated immune responseGO:0023819.8HLA-DRB1, HLA-DQB1
2interferon-gamma-mediated signaling pathwayGO:0603339.5HLA-DQB1, HLA-DRB1, HLA-DQA1
3humoral immune response mediated by circulating immunoglobulinGO:0024559.5HLA-DRB1, HLA-DQB1
4T cell costimulationGO:0312959.5HLA-DQA1, HLA-DRB1, HLA-DQB1
5T cell receptor signaling pathwayGO:0508529.4HLA-DQA1, HLA-DRB1, HLA-DQB1
6protein tetramerizationGO:0512629.4TP53, HLA-DRB1
7antigen processing and presentation of exogenous peptide antigen via MHC class IIGO:0198869.4HLA-DQB1, HLA-DRB1, HLA-DQA1
8immune responseGO:0069559.1HLA-DQB1, HLA-DRB1, HLA-DQA1, IL8
9response to antibioticGO:0466779.0TP53, IL6
10cytokine-mediated signaling pathwayGO:0192218.2IL6, HLA-DQA1, HLA-DRB1, HLA-DQB1, IFNB1
11negative regulation of cell proliferationGO:0082858.1IFNB1, IL8, IL6, TP53
12positive regulation of transcription from RNA polymerase II promoterGO:0459447.9IFNB1, NFIX, NFIC, IL6, TP53

Molecular functions related to Common Wart according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MHC class II receptor activityGO:0323959.3HLA-DQA1, HLA-DRB1, HLA-DQB1

Products for genes affiliated with Common Wart

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Common Wart

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet