MCID: CMM008
MIFTS: 36

Communicating Hydrocephalus malady

Categories: Neuronal diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Communicating Hydrocephalus

Aliases & Descriptions for Communicating Hydrocephalus:

Name: Communicating Hydrocephalus 12 29 52 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:1573
ICD10 33 G91.0
ICD9CM 35 331.3
MeSH 42 D006849
NCIt 47 C34501
SNOMED-CT 64 271569006 59013007
UMLS 69 C0009451

Summaries for Communicating Hydrocephalus

MalaCards based summary : Communicating Hydrocephalus is related to congenital communicating hydrocephalus and congenital non-communicating hydrocephalus. An important gene associated with Communicating Hydrocephalus is TGFB1 (Transforming Growth Factor Beta 1), and among its related pathways/superpathways is Alzheimers Disease Pathway. Affiliated tissues include testes, brain and b cells.

Related Diseases for Communicating Hydrocephalus

Diseases in the Communicating Hydrocephalus family:

Congenital Communicating Hydrocephalus

Diseases related to Communicating Hydrocephalus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 90)
id Related Disease Score Top Affiliating Genes
1 congenital communicating hydrocephalus 12.1
2 congenital non-communicating hydrocephalus 12.0
3 hydrocephalus, endocardial fibroelastosis, and cataracts 11.0
4 kozlowski brown hardwick syndrome 11.0
5 cole-carpenter syndrome 10.8
6 chiari malformation 10.8
7 coenurosis 10.8
8 hydrocephalus 10.7
9 keratosis palmoplantaris striata 10.1 APOE MAPT
10 bone dysplasia azouz type 10.0 APOE MAPT
11 cerebritis 10.0
12 meningitis 10.0
13 dementia 10.0
14 limited scleroderma 9.9 APOE PTGDS SERPINA3
15 arachnoiditis 9.9
16 meckel syndrome 10 9.9 APOE MAPT SERPINA3
17 machado-joseph disease 9.9 CCDC88C MPDZ
18 coenzyme q10 deficiency, primary, 1 9.9 ADAMTS2 APOE MAPT
19 severe congenital nemaline myopathy 9.9 APOE MAPT
20 contagious pustular dermatitis 9.9 APOE MAPT SERPINA3
21 cardiomyopathy, dilated, 1u 9.9 ADAMTS2 APOE MAPT
22 central bilateral macrogyria 9.8 CCDC88C HYDIN MPDZ
23 allergic bronchopulmonary aspergillosis, familial 9.8 APOE MAPT SERPINA3
24 personality disorder 9.8 ADAMTS2 APOE MAPT
25 choroiditis 9.8
26 glioblastoma 9.8
27 lupus erythematosus 9.7
28 aneurysm 9.7
29 intracranial hypertension 9.7
30 ependymoma 9.7
31 systemic lupus erythematosus 9.7
32 papilledema 9.7
33 transposition of the great arteries 9.7
34 cerebellar hypoplasia 9.7
35 glioblastoma multiforme 9.7
36 arachnoid cysts 9.7
37 glioma 9.7
38 hydrops fetalis 9.7
39 tetralogy of fallot 9.5
40 cellular ependymoma 9.5
41 metachromatic leukodystrophy 9.5
42 thrombosis 9.5
43 normal pressure hydrocephalus 9.5
44 peritonitis 9.5
45 vascular malformation 9.5
46 coffin-lowry syndrome 9.5
47 congenital myopathy 9.5
48 hepatitis c 9.5
49 eosinophilic meningitis 9.5
50 gaucher's disease 9.5

Comorbidity relations with Communicating Hydrocephalus via Phenotypic Disease Network (PDN):


Acute Cystitis Alzheimer Disease
Decubitus Ulcer Deficiency Anemia
Hypertension, Essential Hypothyroidism
Obstructive Hydrocephalus Parkinson Disease, Late-Onset
Schizophreniform Disorder Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Communicating Hydrocephalus:



Diseases related to Communicating Hydrocephalus

Symptoms & Phenotypes for Communicating Hydrocephalus

Drugs & Therapeutics for Communicating Hydrocephalus

Interventional clinical trials:


id Name Status NCT ID Phase
1 A Randomised Controlled Trial of Lumbar Drainage to Treat Communicating Hydrocephalus After Severe Intraventricular Hemorrhage Completed NCT01041950 Phase 2, Phase 3
2 ETV Versus Shunt Surgery in Normal Pressure Hydrocephalus Terminated NCT00946127 Phase 3
3 Third Ventriculostomy Versus Shunt for Children With Hydrocephalus Completed NCT01801267
4 Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in Life Completed NCT01367977
5 Improved Analysis Methods for Infusion Tests Completed NCT01319136
6 Keyhole Surgery for the Positioning of the Distal Catheter in Ventricular Peritoneal Shunt Placement Completed NCT01739179
7 Study of Choroid Plexus Cauderization in Patients With Hydrocephalus Recruiting NCT02900222
8 Prospective Shunt Complication Study Recruiting NCT02778997
9 Head Circumference Growth in Children Who Develop Multiple Sclerosis Later in Life Withdrawn NCT01377805

Search NIH Clinical Center for Communicating Hydrocephalus

Genetic Tests for Communicating Hydrocephalus

Genetic tests related to Communicating Hydrocephalus:

id Genetic test Affiliating Genes
1 Communicating Hydrocephalus 29

Anatomical Context for Communicating Hydrocephalus

MalaCards organs/tissues related to Communicating Hydrocephalus:

39
Testes, Brain, B Cells

Publications for Communicating Hydrocephalus

Articles related to Communicating Hydrocephalus:

(show top 50) (show all 296)
id Title Authors Year
1
Secondary communicating hydrocephalus management by implantation of external ventricular shunt and minimal gradual increase of cerebrospinal fluid pressure. ( 28484529 )
2017
2
Cerebrospinal fluid dynamics study in communicating hydrocephalus. ( 28484522 )
2017
3
Evaluation of the flow of cerebrospinal fluid as well as gender and age characteristics in patients with communicating hydrocephalus, using phase-contrast magnetic resonance imaging. ( 26848963 )
2016
4
Communicating Hydrocephalus Due to Traumatic Lumbar Spine Injury: Case Report and Literature Review. ( 27323322 )
2016
5
Intraventricular administration of urokinase as a novel therapeutic approach for communicating hydrocephalus. ( 27614013 )
2016
6
Communicating hydrocephalus associated with small- to medium-sized vestibular schwannomas: clinical significance of the tumor apparent diffusion coefficient map. ( 27423198 )
2016
7
Analysis of risk factors to predict communicating hydrocephalus following gamma knife radiosurgery for intracranial schwannoma. ( 27882725 )
2016
8
Communicating Hydrocephalus Associated with Intracranial Schwannoma Treated by Gamma Knife Radiosurgery. ( 26585729 )
2016
9
Imaging of Communicating Hydrocephalus. ( 27063660 )
2016
10
Ventricular Volume Load Reveals the Mechanoelastic Impact of Communicating Hydrocephalus on Dynamic Cerebral Autoregulation. ( 27415784 )
2016
11
New concept of the pathogenesis and therapeutic orientation of acquired communicating hydrocephalus. ( 27115894 )
2016
12
The prevalence of cardiovascular disease in non-communicating hydrocephalus. ( 27455422 )
2016
13
Diffusion tensor imaging with direct cytopathological validation: characterisation of decorin treatment in experimental juvenile communicating hydrocephalus. ( 27246837 )
2016
14
Surgical management of non-communicating hydrocephalus in patients: meta-analysis and comparison of endoscopic third ventriculostomy and ventriculoperitoneal shunt. ( 25699529 )
2015
15
Communicating hydrocephalus, a long-term complication of dural tear during lumbar spine surgery. ( 26521076 )
2015
16
Persistent communicating hydrocephalus in adult tuberous sclerosis patients: a possible therapeutic role for everolimus. ( 25524658 )
2015
17
Association between ventricular volume measures and pulsatile and static intracranial pressure scores in non-communicating hydrocephalus. ( 25680584 )
2015
18
A hypothesis of traumatic subdural effusion associated with communicating hydrocephalus in infants and its management. ( 25675020 )
2015
19
A severe case of systemic lupus erythematosus with increased pressure communicating hydrocephalus. ( 27708931 )
2015
20
Communicating hydrocephalus in systemic lupus erythematosus. ( 25031142 )
2014
21
Pemetrexed and communicating hydrocephalus. ( 24940146 )
2014
22
Communicating hydrocephalus following eosinophilic meningitis is pathogenic for chronic Viliuisk encephalomyelitis in Northeastern Siberia. ( 24586232 )
2014
23
Infantile holocord cellular ependymoma with communicating hydrocephalus: unusual presentation of a rare case. ( 23512254 )
2014
24
Early manifestation of communicating hydrocephalus after fractionated stereotactic radiotherapy for aggressive giant atypical prolactinoma. ( 24778068 )
2014
25
Microgravity environment and compensatory: Decompensatory phases for intracranial hypertension form new perspectives to explain mechanism underlying communicating hydrocephalus and its related disorders. ( 24891884 )
2014
26
Changes in neural stem cells in the subventricular zone in a rat model of communicating hydrocephalus. ( 24996196 )
2014
27
Communicating hydrocephalus with reversible cognitive impairment. ( 24589982 )
2014
28
Thrombin-induced TGF-I^1 pathway: a cause of communicating hydrocephalus post subarachnoid hemorrhage. ( 23338707 )
2013
29
Communicating hydrocephalus accompanied by arachnoid cyst in aneurismal subarachnoid hemorrhage. ( 24729958 )
2013
30
Molecular targets for neonatal communicating hydrocephalus, putting shunts out to pasture? ( 23511831 )
2013
31
Aqueductal flow of cerebrospinal fluid (CSF) and anatomical configuration of the cerebral aqueduct (AC) in patients with communicating hydrocephalus--the trumpet sign. ( 23318053 )
2013
32
Communicating hydrocephalus in metachromatic leukodystrophy. ( 23830584 )
2013
33
Procollagen Type I C-terminal propeptide, procollagen Type III N-terminal propeptide, hyaluronic acid, and laminin in the cerebrospinal fluid of rats with communicating hydrocephalus. ( 23560698 )
2013
34
Is endoscopic third ventriculostomy superior to shunts in patients with non-communicating hydrocephalus? A systematic review and meta-analysis of the evidence. ( 23456239 )
2013
35
Comparative study of lumboperitoneal shunt versus ventriculoperitoneal shunt in post meningitis communicating hydrocephalus in children. ( 24262455 )
2013
36
Gravity assisted vs. medium pressure valves for communicating hydrocephalus show similar valve-revision rates. ( 23989996 )
2013
37
Hearing loss following ventriculoperitoneal shunt in communicating hydrocephalus patients: a pilot study. ( 24318317 )
2013
38
Communicating hydrocephalus caused by an unruptured perimedullary arteriovenous fistula in the lumbar region of an infant. ( 23240850 )
2013
39
Clinical characteristics and neuroimaging findings in 12 cases of recurrent glioblastoma with communicating hydrocephalus. ( 23883558 )
2013
40
Decorin prevents the development of juvenile communicating hydrocephalus. ( 23983032 )
2013
41
Communicating hydrocephalus and vestibular schwannomas: etiology, treatment, and long-term follow-up. ( 24436891 )
2013
42
Communicating hydrocephalus due to cerebral venous sinus thrombosis treated with ventriculoperitoneal shunt. ( 23349607 )
2012
43
Neocortical capillary flow pulsatility is not elevated in experimental communicating hydrocephalus. ( 21934694 )
2012
44
Reactive gliosis and neuroinflammation in rats with communicating hydrocephalus. ( 22583796 )
2012
45
Successful medical treatment in a child with E. coli ESBL meningitis with acute communicating hydrocephalus and ventricular empyema: a case report. ( 23513480 )
2012
46
Atypical presentation of delayed communicating hydrocephalus after supratentorial glioma resection with opening of the ventricles. ( 21973062 )
2012
47
Historical considerations of the predominance of lumboperitoneal shunt for treatment of adult communicating hydrocephalus in Kumamoto, Japan. ( 22397970 )
2012
48
Morphological and behavioral changes in the pathogenesis of a novel mouse model of communicating hydrocephalus. ( 22291910 )
2012
49
The risk factors of symptomatic communicating hydrocephalus after stereotactic radiosurgery for unilateral vestibular schwannoma: the implication of brain atrophy. ( 22494587 )
2012
50
The role of endoscopic third ventriculostomy in the treatment of communicating hydrocephalus. ( 22120350 )
2012

Variations for Communicating Hydrocephalus

Expression for Communicating Hydrocephalus

Search GEO for disease gene expression data for Communicating Hydrocephalus.

Pathways for Communicating Hydrocephalus

Pathways related to Communicating Hydrocephalus according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.28 APOE MAPT

GO Terms for Communicating Hydrocephalus

Cellular components related to Communicating Hydrocephalus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 blood microparticle GO:0072562 8.8 APOE SERPINA3 TGFB1

Biological processes related to Communicating Hydrocephalus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytoplasmic microtubule organization GO:0031122 9.26 CCDC88C MAPT
2 response to radiation GO:0009314 9.16 OGG1 TGFB1
3 negative regulation of blood vessel endothelial cell migration GO:0043537 8.96 APOE TGFB1
4 positive regulation of superoxide anion generation GO:0032930 8.62 MAPT TGFB1

Molecular functions related to Communicating Hydrocephalus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 microtubule binding GO:0008017 9.13 CCDC88C MAPT OGG1
2 lipoprotein particle binding GO:0071813 8.62 APOE MAPT

Sources for Communicating Hydrocephalus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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