MCID: CMM008
MIFTS: 37

Communicating Hydrocephalus malady

Categories: Neuronal diseases, Blood diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Communicating Hydrocephalus

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Aliases & Descriptions for Communicating Hydrocephalus:

Name: Communicating Hydrocephalus 11 27 50 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:1573
ICD1030 G91.0
ICD9CM32 331.3
SNOMED-CT62 271569006, 59013007
MeSH39 D006849
NCIt45 C34501

Summaries for Communicating Hydrocephalus

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MalaCards based summary: Communicating Hydrocephalus is related to congenital communicating hydrocephalus and congenital non-communicating hydrocephalus. An important gene associated with Communicating Hydrocephalus is TGFB1 (Transforming Growth Factor Beta 1), and among its related pathways is Alzheimers Disease Pathway. Affiliated tissues include testes, brain and b cells, and related mouse phenotype behavior/neurological.

Related Diseases for Communicating Hydrocephalus

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Diseases in the Communicating Hydrocephalus family:

Congenital Communicating Hydrocephalus

Diseases related to Communicating Hydrocephalus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 97)
idRelated DiseaseScoreTop Affiliating Genes
1congenital communicating hydrocephalus12.1
2congenital non-communicating hydrocephalus12.0
3hydrocephalus, endocardial fibroelastosis, and cataracts11.0
4kozlowski brown hardwick syndrome11.0
5chiari malformation type ii10.9
6coenurosis10.9
7cole-carpenter syndrome10.9
8hydrocephalus10.7
9cholesterol embolism10.3NEXN, OGG1
10gynecomastia10.3OGG1, TGFB1
11chronic recurrent multifocal osteomyelitis10.3NEXN, OGG1
12asbestosis10.2OGG1, TGFB1
13fibrosclerosis of breast10.2SERPINA3, TGFB1
14ichthyosis lamellar 110.2HYDIN, PTGDS, TGFB1
15postinfectious vasculitis10.1APOE, MAPT
16testicular seminoma10.0APOE, MAPT
17cerebritis10.0
18colon kaposi sarcoma10.0ADAMTS2, MAPT
19dementia10.0
20meningitis10.0
21arachnoiditis9.9
22anti-p200 pemphigoid9.9APOE, MAPT
23microsporidiosis9.8APOE, MAPT
24choroiditis9.8
25glioblastoma9.8
26gemistocytic astrocytoma9.8APOE, MAPT, TGFB1
27systemic lupus erythematosus9.7
28lupus erythematosus9.7
29intracranial hypertension9.7
30ependymoma9.7
31aneurysm9.7
32rheumatic disease9.7APOE, PTGDS, SERPINA3
33parkinson disease 19.7ADAMTS2, APOE, MAPT
34pick disease9.7ADAMTS2, APOE, MAPT
35avoidant personality disorder9.7ADAMTS2, APOE, MAPT
36meier-gorlin syndrome 59.7APOE, MAPT
37vaginal tubular adenoma9.7ADAMTS2, APOE, MAPT
38angiomyolipoma9.7ADAMTS2, APOE, MAPT
39cerebellar hypoplasia9.7
40papilledema9.7
41glioblastoma multiforme9.7
42arachnoid cysts9.7
43glioma9.7
44hydrops fetalis9.7
45transposition of the great arteries9.7
46anaerobic pneumonia9.6APOE, MAPT, SERPINA3
47allergic bronchopulmonary aspergillosis, familial9.6APOE, MAPT, SERPINA3
48nosophobia9.5APOE, MAPT
49schizophrenia9.5
50tetralogy of fallot9.5

Comorbidity relations with Communicating Hydrocephalus via Phenotypic Disease Network (PDN):


Alzheimer DiseaseAcute Cystitis
Decubitus UlcerHypertension, Essential
Obstructive HydrocephalusParkinson Disease, Late-Onset
Transient Cerebral IschemiaDeficiency Anemia
HypothyroidismSchizophreniform Disorder

Graphical network of the top 20 diseases related to Communicating Hydrocephalus:



Diseases related to communicating hydrocephalus

Symptoms & Phenotypes for Communicating Hydrocephalus

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MGI Mouse Phenotypes related to Communicating Hydrocephalus according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053867.6APOE, HYDIN, MAPT, OGG1, PTGDS, SNPH

Drugs & Therapeutics for Communicating Hydrocephalus

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Interventional clinical trials:

idNameStatusNCT IDPhase
1A Randomised Controlled Trial of Lumbar Drainage to Treat Communicating Hydrocephalus After Severe Intraventricular HemorrhageCompletedNCT01041950Phase 2, Phase 3
2ETV Versus Shunt Surgery in Normal Pressure HydrocephalusTerminatedNCT00946127Phase 3
3Third Ventriculostomy Versus Shunt for Children With HydrocephalusCompletedNCT01801267
4Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in LifeCompletedNCT01367977
5Improved Analysis Methods for Infusion TestsCompletedNCT01319136
6Keyhole Surgery for the Positioning of the Distal Catheter in Ventricular Peritoneal Shunt PlacementCompletedNCT01739179
7Prospective Shunt Complication StudyRecruitingNCT02778997
8Study of Choroid Plexus Cauderization in Patients With HydrocephalusNot yet recruitingNCT02900222
9Head Circumference Growth in Children Who Develop Multiple Sclerosis Later in LifeWithdrawnNCT01377805

Search NIH Clinical Center for Communicating Hydrocephalus

Genetic Tests for Communicating Hydrocephalus

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Genetic tests related to Communicating Hydrocephalus:

id Genetic test Affiliating Genes
1 Communicating Hydrocephalus27

Anatomical Context for Communicating Hydrocephalus

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MalaCards organs/tissues related to Communicating Hydrocephalus:

36
Testes, Brain, B cells

Publications for Communicating Hydrocephalus

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Articles related to Communicating Hydrocephalus:

(show top 50)    (show all 294)
idTitleAuthorsYear
1
Analysis of risk factors to predict communicating hydrocephalus following gamma knife radiosurgery for intracranial schwannoma. (27882725)
2016
2
The prevalence of cardiovascular disease in non-communicating hydrocephalus. (27455422)
2016
3
Evaluation of the flow of cerebrospinal fluid as well as gender and age characteristics in patients with communicating hydrocephalus, using phase-contrast magnetic resonance imaging. (26848963)
2016
4
New concept of the pathogenesis and therapeutic orientation of acquired communicating hydrocephalus. (27115894)
2016
5
Imaging of Communicating Hydrocephalus. (27063660)
2016
6
Intraventricular administration of urokinase as a novel therapeutic approach for communicating hydrocephalus. (27614013)
2016
7
Communicating Hydrocephalus Associated with Intracranial Schwannoma Treated by Gamma Knife Radiosurgery. (26585729)
2016
8
Diffusion tensor imaging with direct cytopathological validation: characterisation of decorin treatment in experimental juvenile communicating hydrocephalus. (27246837)
2016
9
Ventricular Volume Load Reveals the Mechanoelastic Impact of Communicating Hydrocephalus on Dynamic Cerebral Autoregulation. (27415784)
2016
10
Communicating Hydrocephalus Due to Traumatic Lumbar Spine Injury: Case Report and Literature Review. (27323322)
2016
11
Communicating hydrocephalus associated with small- to medium-sized vestibular schwannomas: clinical significance of the tumor apparent diffusion coefficient map. (27423198)
2016
12
A severe case of systemic lupus erythematosus with increased pressure communicating hydrocephalus. (27708931)
2015
13
Association between ventricular volume measures and pulsatile and static intracranial pressure scores in non-communicating hydrocephalus. (25680584)
2015
14
Communicating hydrocephalus, a long-term complication of dural tear during lumbar spine surgery. (26521076)
2015
15
Persistent communicating hydrocephalus in adult tuberous sclerosis patients: a possible therapeutic role for everolimus. (25524658)
2015
16
Surgical management of non-communicating hydrocephalus in patients: meta-analysis and comparison of endoscopic third ventriculostomy and ventriculoperitoneal shunt. (25699529)
2015
17
A hypothesis of traumatic subdural effusion associated with communicating hydrocephalus in infants and its management. (25675020)
2015
18
Communicating hydrocephalus in systemic lupus erythematosus. (25031142)
2014
19
Communicating hydrocephalus following eosinophilic meningitis is pathogenic for chronic Viliuisk encephalomyelitis in Northeastern Siberia. (24586232)
2014
20
Pemetrexed and communicating hydrocephalus. (24940146)
2014
21
Microgravity environment and compensatory: Decompensatory phases for intracranial hypertension form new perspectives to explain mechanism underlying communicating hydrocephalus and its related disorders. (24891884)
2014
22
Early manifestation of communicating hydrocephalus after fractionated stereotactic radiotherapy for aggressive giant atypical prolactinoma. (24778068)
2014
23
Communicating hydrocephalus with reversible cognitive impairment. (24589982)
2014
24
Changes in neural stem cells in the subventricular zone in a rat model of communicating hydrocephalus. (24996196)
2014
25
Infantile holocord cellular ependymoma with communicating hydrocephalus: unusual presentation of a rare case. (23512254)
2014
26
Aqueductal flow of cerebrospinal fluid (CSF) and anatomical configuration of the cerebral aqueduct (AC) in patients with communicating hydrocephalus--the trumpet sign. (23318053)
2013
27
Communicating hydrocephalus caused by an unruptured perimedullary arteriovenous fistula in the lumbar region of an infant. (23240850)
2013
28
Comparative study of lumboperitoneal shunt versus ventriculoperitoneal shunt in post meningitis communicating hydrocephalus in children. (24262455)
2013
29
Hearing loss following ventriculoperitoneal shunt in communicating hydrocephalus patients: a pilot study. (24318317)
2013
30
Communicating hydrocephalus in metachromatic leukodystrophy. (23830584)
2013
31
Procollagen Type I C-terminal propeptide, procollagen Type III N-terminal propeptide, hyaluronic acid, and laminin in the cerebrospinal fluid of rats with communicating hydrocephalus. (23560698)
2013
32
Molecular targets for neonatal communicating hydrocephalus, putting shunts out to pasture? (23511831)
2013
33
Clinical characteristics and neuroimaging findings in 12 cases of recurrent glioblastoma with communicating hydrocephalus. (23883558)
2013
34
Decorin prevents the development of juvenile communicating hydrocephalus. (23983032)
2013
35
Communicating hydrocephalus accompanied by arachnoid cyst in aneurismal subarachnoid hemorrhage. (24729958)
2013
36
Is endoscopic third ventriculostomy superior to shunts in patients with non-communicating hydrocephalus? A systematic review and meta-analysis of the evidence. (23456239)
2013
37
Communicating hydrocephalus and vestibular schwannomas: etiology, treatment, and long-term follow-up. (24436891)
2013
38
Thrombin-induced TGF-I^1 pathway: a cause of communicating hydrocephalus post subarachnoid hemorrhage. (23338707)
2013
39
Gravity assisted vs. medium pressure valves for communicating hydrocephalus show similar valve-revision rates. (23989996)
2013
40
Successful medical treatment in a child with E. coli ESBL meningitis with acute communicating hydrocephalus and ventricular empyema: a case report. (23513480)
2012
41
Neocortical capillary flow pulsatility is not elevated in experimental communicating hydrocephalus. (21934694)
2012
42
Efficacy of endoscopic third ventriculostomy in non-communicating hydrocephalus. (24397077)
2012
43
Atypical presentation of delayed communicating hydrocephalus after supratentorial glioma resection with opening of the ventricles. (21973062)
2012
44
The risk factors of symptomatic communicating hydrocephalus after stereotactic radiosurgery for unilateral vestibular schwannoma: the implication of brain atrophy. (22494587)
2012
45
Morphological and behavioral changes in the pathogenesis of a novel mouse model of communicating hydrocephalus. (22291910)
2012
46
Communicating hydrocephalus due to cerebral venous sinus thrombosis treated with ventriculoperitoneal shunt. (23349607)
2012
47
Micro-fabricated shunt to mimic arachnoid granulations for the treatment of communicating hydrocephalus. (22327701)
2012
48
The role of endoscopic third ventriculostomy in the treatment of communicating hydrocephalus. (22120350)
2012
49
Historical considerations of the predominance of lumboperitoneal shunt for treatment of adult communicating hydrocephalus in Kumamoto, Japan. (22397970)
2012
50
Reactive gliosis and neuroinflammation in rats with communicating hydrocephalus. (22583796)
2012

Variations for Communicating Hydrocephalus

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Expression for genes affiliated with Communicating Hydrocephalus

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Search GEO for disease gene expression data for Communicating Hydrocephalus.

Pathways for genes affiliated with Communicating Hydrocephalus

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Pathways related to Communicating Hydrocephalus according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.4APOE, MAPT

GO Terms for genes affiliated with Communicating Hydrocephalus

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Cellular components related to Communicating Hydrocephalus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:00725629.1APOE, SERPINA3, TGFB1

Biological processes related to Communicating Hydrocephalus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of blood vessel endothelial cell migrationGO:004353710.0APOE, TGFB1
2response to radiationGO:00093149.9OGG1, TGFB1

Molecular functions related to Communicating Hydrocephalus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lipoprotein particle bindingGO:00718139.4APOE, MAPT

Sources for Communicating Hydrocephalus

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet