MCID: CNG069
MIFTS: 18

Congenital Cytomegalovirus malady

Summaries for Congenital Cytomegalovirus

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32MalaCards
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MalaCards: Congenital Cytomegalovirus is related to sensorineural hearing loss and enlarged vestibular aqueduct. An important gene associated with Congenital Cytomegalovirus is GJB2 (gap junction protein, beta 2, 26kDa), and among its related pathways is Gap junction trafficking. The compounds 10panx and scrambled 10panx have been mentioned in the context of this disorder.

Aliases & Classifications for Congenital Cytomegalovirus

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42NIH Rare Diseases
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Aliases & Descriptions:

congenital cytomegalovirus 42


Related Diseases for Congenital Cytomegalovirus

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17GeneCards, 18GeneDecks
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Diseases related to Congenital Cytomegalovirus via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 73)
idRelated DiseaseScoreTop Affiliating Genes
1sensorineural hearing loss30.6GJB2, GJB6
2enlarged vestibular aqueduct29.8GJB6, GJB2
3cerebritis10.2
4chorioretinitis10.1
5retinitis10.1
6hydrocephalus10.0
7hypertension10.0
8labyrinthitis10.0
9oligohydramnios10.0
10pneumonia10.0
11fetal cytomegalovirus syndrome10.0
12erythrokeratodermia variabilis10.0GJB2
13cystic fibrosis10.0GJB2
14melanoma10.0GJB2
15palmoplantar keratosis10.0GJB6
16keratoderma10.0GJB2
17usher syndrome10.0GJB2
18cryoglobulinemic vasculitis10.0CD40LG
19cryoglobulinemia10.0CD40LG
20dfnb 1 nonsyndromic hearing loss and deafness10.0GJB2, GJB6
21dfna 3 nonsyndromic hearing loss and deafness10.0GJB2, GJB6
22bart-pumphrey syndrome10.0GJB2, GJB6
23hidrotic ectodermal dysplasia 210.0GJB2, GJB6
24dfnb110.0GJB6, GJB2
25clouston syndrome10.0GJB2, GJB6
26colorectal cancer10.0RNASET2, GJB2
27cholecystitis10.0GPT
28rubella10.0CD40LG
29hyperuricemia10.0GPT
30cholelithiasis10.0GPT
31scrub typhus10.0CD40LG, GPT
32autoimmune hepatitis10.0GPT, CD40LG
33hepatitis e10.0GPT, CD40LG
34primary biliary cirrhosis10.0GPT, CD40LG
35periventricular leukomalacia9.9
36leukemoid reaction9.9
37twin-to-twin transfusion syndrome9.9
38autistic disorder9.9
39wiskott-aldrich syndrome9.9
40systemic lupus erythematosus9.9
41diabetes insipidus9.9
42thyroid hormone resistance syndrome9.9
43microcephaly9.9
44neuronitis9.9
45microphthalmia9.9
46acquired immunodeficiency syndrome9.9
47parotitis9.9
48congenital toxoplasmosis9.9
49horner's syndrome9.9
50hydranencephaly9.9

Graphical network of the top 20 diseases related to Congenital Cytomegalovirus:



Diseases related to congenital cytomegalovirus

Clinical Features for Congenital Cytomegalovirus

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Drugs & Therapeutics for Congenital Cytomegalovirus

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Congenital Cytomegalovirus

Drug clinical trials:

Search ClinicalTrials for Congenital Cytomegalovirus

Search NIH Clinical Center for Congenital Cytomegalovirus

Search CenterWatch for Congenital Cytomegalovirus

Genetic Tests for Congenital Cytomegalovirus

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Anatomical Context for Congenital Cytomegalovirus

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Animal Models for Congenital Cytomegalovirus or affiliated genes

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Publications for Congenital Cytomegalovirus

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Genetic Variations for Congenital Cytomegalovirus

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Expression for genes affiliated with Congenital Cytomegalovirus

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Congenital Cytomegalovirus

Search GEO for disease gene expression data for Congenital Cytomegalovirus.

Pathways for genes affiliated with Congenital Cytomegalovirus

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53Reactome
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Pathways related to Congenital Cytomegalovirus according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.6GJB2, GJB6

Compounds for genes affiliated with Congenital Cytomegalovirus

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59Tocris Bioscience, 28IUPHAR, 24HMDB, 44Novoseek, 11DrugBank, 2BitterDB, 49PharmGKB
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Compounds related to Congenital Cytomegalovirus according to GeneCards/GeneDecks:

(show all 18)
idCompoundScoreTop Affiliating Genes
110panx5910.0GJB2, GJB6
2scrambled 10panx5910.0GJB2, GJB6
3carbenoxolone disodium599.9GJB2, GJB6
4gap 27599.9GJB2, GJB6
5octanol28 2410.9GJB6, GJB2
6carbenoxolone28 44 1111.9GJB2, GJB6
7ca2+289.9GJB2, GJB6
8flufenamic acid44 28 2 1112.9GJB6, GJB2
9ursodeoxycholic acid44 11 2411.3GPT, CD40LG
10mycophenolate mofetil44 49 1111.2CD40LG, GPT
11valproate449.2GPT, CD40LG
12fenofibrate44 49 1111.2GPT, CD40LG
13ribavirin44 49 1111.1CD40LG, GPT
14ivig449.1GPT, CD40LG
15vitamin b12449.0CD40LG, GPT
16pravastatin44 49 28 11 2413.0GPT, CD40LG
17neopterin448.9GPT, CD40LG
18aspartate448.4GPT, GJB2, CD40LG

GO Terms for genes affiliated with Congenital Cytomegalovirus

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16Gene Ontology
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Cellular components related to Congenital Cytomegalovirus according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1connexon complexGO:0059229.6GJB2, GJB6

Products for genes affiliated with Congenital Cytomegalovirus

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Congenital Cytomegalovirus

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet